Archive for the ‘Viruses’ Category

TBD Serochip Will Identify Six Tick Borne Pathogens

https://www.mailman.columbia.edu/public-health-now/news/first-multiplex-test-tick-borne-diseases

INFECTIOUS DISEASE Feb. 16 2018

First Multiplex Test for Tick-Borne Diseases

PROMISING TO REVOLUTIONIZE DIAGNOSIS, A SINGLE BLOOD TEST CAN NOW ACCURATELY DETECT IF SOMEONE HAS LYME DISEASE AND/OR ONE OF SEVEN OTHER TICK-BORNE DISEASES

A new blood test called the Tick-Borne Disease Serochip (TBD Serochip) promises to revolutionize the diagnosis of tick-borne disease by offering a single test to identify and distinguish between Borrelia burgdorferi, the pathogen responsible for Lyme disease, and seven other tick-borne pathogens. Led by scientists at the Center for Infection and Immunity (CII) at Columbia University’s Mailman School of Public Health, the research team reports details on the new test in the journal Nature Scientific Reports.

The researchers—who also include scientists from the Centers for Disease Control and Prevention, National Institute of Allergy and Infectious Diseases, Roche Sequencing Solutions, Farmingdale State College, and Stony Brook University—sought to improve on existing tests for tick-borne diseases (TBDs), which have limited diagnostic accuracy and cannot test for more than one infection simultaneously. Currently, diagnosis of Lyme disease, the most common TBD, requires two separate tests. This cumbersome approach also relies on subjective criteria for the interpretation of results, and accurately identifies fewer than 40 percent of patients with early disease and results in false positives 28 percent of the time. The accuracy of the method used to diagnose TBDs Babesia, Anaplasma, Ehrlichia, and Rickettsia varies widely among testing laboratories. And for other tick-borne agents, specific blood tests are not yet available, or in the case of the potentially deadly Powassan virus or Heartland virus, are only performed in specialized laboratories.

“The number of Americans diagnosed with tick-borne disease is steadily increasing as tick populations have expanded geographically,” says Rafal Tokarz, PhD. “Each year, approximately 3 million clinical specimens are tested for TBDs in the U.S. Nonetheless, the true incidence of TBDs is likely greatly underestimated, as patients with presumed TBDs are rarely tested for the full range of tick-borne agents, and only a fraction of positive cases are properly reported,” adds Nischay Mishra, PhD. Co-lead authors Tokarz and Mishra are associate research scientists in the Center for Infection and Immunity.

The TBD Serochip can simultaneously test for the presence of antibodies in blood to more than 170,000 individual protein fragments. Version 1.0 can identify exposure to eight tick-borne pathogens present in the U.S., including Anaplasma phagocytophilum (agent of human granulocytic anaplasmosis), Babesia microti (babesiosis), Borrelia burgdorferi (Lyme disease), Borrelia miyamotoi, Ehrlichia chaffeensis (human monocytic ehrlichiosis), Rickettsia rickettsii (Rocky Mountain spotted fever), Heartland virus and Powassan virus. The researchers also included Long Island tick rhabdovirus, a novel virus they recently discovered in Amblyomma americanum ticks. As new tick-borne infectious agents are discovered, the TBD-Serochip will be modified to target them—a process the researchers say can be done in less than four weeks.

The TBD Serochip is also able to identify whether an individual is infected with more than one tick-borne pathogen. Individual ticks are frequently infected with more than one agent; Ixodes scapularis ticks alone can transmit at least five human pathogens. Evidence of exposure to other tick-borne pathogens in patients with Lyme disease has been well documented. In the new paper, the researchers report finding antibodies to another agent in 26 percent of blood specimens from patients with TBD.

In addition to its utility as a diagnostic platform, the TBD Serochip also provides a powerful research tool for studies of TBDs. The technology can be employed to discriminate individual antibody responses in patients with TBD and thus examine the interplay of TBD agents on disease manifestation and progression. It can also be used to assess the impact of genetic diversity of tick-borne pathogens on the host immune response.

“Diagnosing tick-borne illness is a difficult journey for patients, delaying effecting treatment,” says senior author W. Ian Lipkin, MD, director of CII and John Snow Professor of Epidemiology at Columbia University’s Mailman School of Public Health. “The TBD Serochip promises to make diagnosis far easier, offering a single, accurate test for eight different TBDs. Early detection of infection enables rapid and appropriate treatment.”

Co-authors include Thomas Briese, Teresa Tagliafierro, Stephen Sameroff, Adrian Caciula, Lokendrasingh Chauhan, of CII; Jigar Patel and Eric Sullivan of Roche Sequencing Solutions, Madison, WI; Azad Gucwa of Farmingdale State College, Farmingdale, NY; Brian Fallon of Columbia University; Marc Golightly of Stony Brook University; Claudia Molins and Martin Schriefer of Centers for Disease Control and Prevention; and Adriana Marques of National Institute of Allergy and Infectious Diseases.

This study was funded through grants from the Steven & Alexandra Cohen Foundation and the National Institutes of Allergy and Infectious Diseases (AI109761). The content of study does not necessarily reflect the views or policies of the Department of Health and Human Services, nor does mention of trade names, commercial products, or organizations imply endorsement by the U.S. government. CII has filed an invention report and provisional patent application for the technology.

Study Shows 630% More Aerosolized Flu Virus Particles Emitted by Flu-Vaccinated – A Message to Ethical MD’s

http://www.pnas.org/content/115/5/1081

Infectious virus in exhaled breath of symptomatic seasonal influenza cases from a college community

Jing YanMichael GranthamJovan PantelicP. Jacob Bueno de MesquitaBarbara AlbertFengjie LiuSheryl EhrmanDonald K. Milton and EMIT Consortium
  1. Edited by Peter Palese, Icahn School of Medicine at Mount Sinai, New York, NY, and approved December 15, 2017 (received for review September 19, 2017)

Significance

Lack of human data on influenza virus aerosol shedding fuels debate over the importance of airborne transmission. We provide overwhelming evidence that humans generate infectious aerosols and quantitative data to improve mathematical models of transmission and public health interventions. We show that sneezing is rare and not important for—and that coughing is not required for—influenza virus aerosolization. Our findings, that upper and lower airway infection are independent and that fine-particle exhaled aerosols reflect infection in the lung, opened a pathway for a deeper understanding of the human biology of influenza infection and transmission. Our observation of an association between repeated vaccination and increased viral aerosol generation demonstrated the power of our method, but needs confirmation.

Abstract

Little is known about the amount and infectiousness of influenza virus shed into exhaled breath. This contributes to uncertainty about the importance of airborne influenza transmission. We screened 355 symptomatic volunteers with acute respiratory illness and report 142 cases with confirmed influenza infection who provided 218 paired nasopharyngeal (NP) and 30-minute breath samples (coarse >5-µm and fine ≤5-µm fractions) on days 1–3 after symptom onset. We assessed viral RNA copy number for all samples and cultured NP swabs and fine aerosols. We recovered infectious virus from 52 (39%) of the fine aerosols and 150 (89%) of the NP swabs with valid cultures. The geometric mean RNA copy numbers were 3.8 × 104/30-minutes fine-, 1.2 × 104/30-minutes coarse-aerosol sample, and 8.2 × 108 per NP swab. Fine- and coarse-aerosol viral RNA were positively associated with body mass index and number of coughs and negatively associated with increasing days since symptom onset in adjusted models. Fine-aerosol viral RNA was also positively associated with having influenza vaccination for both the current and prior season. NP swab viral RNA was positively associated with upper respiratory symptoms and negatively associated with age but was not significantly associated with fine- or coarse-aerosol viral RNA or their predictors. Sneezing was rare, and sneezing and coughing were not necessary for infectious aerosol generation. Our observations suggest that influenza infection in the upper and lower airways are compartmentalized and independent.

The association of current and prior year vaccination with increased shedding of influenza A might lead one to speculate that certain types of prior immunity promote lung inflammation, airway closure, and aerosol generation. This first observation of the phenomenon needs confirmation. If confirmed, this observation, together with recent literature suggesting reduced protection with annual vaccination, would have implications for influenza vaccination recommendations and policies.

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https://jameslyonsweiler.com/2018/02/02/a-message-to-ethical-mds-the-problem-with-the-2017-8-flu-vaccine-is-the-2016-7-flu-vaccine/  (Please read entire article here by James Lyons Weiler)

Letter to ethical MD’s (snippets below):

The last time the flu vaccine was 60-70% effective was eight years ago.

fluave

“This is the CDC’s data  https://www.cdc.gov/flu/professionals/vaccination/effectiveness-studies.htm  Clearly, Gupta’s “Years” is, in immunological memory, a singular “Year”. Only once out of the last 14 years was the flu vaccine above 59% – that the value was not 60-70%, it was 60%.

This type of misrepresentation is a consistent penchant within the media and of course from the CDC to exaggerate and highly emphasize only positive views and diminish, dismiss, or ignore any negative views on the safety and efficacy of vaccines.

The Jury is In: The Flu Vaccine Reduces its Own Efficacy

Too many studies now exist that have independently come to the same conclusion: increases in the uptake of flu vaccine reduces that vaccine’s effectiveness in the following year – and some studies show the negative effects of mass influenza vaccination last two years.

The studies reporting those results are reviewed in my article, “Diseases with Unknown Etiology Trace Back to Mass Vaccination Against Influenza in 1976“, and they are extensive and damning. https://jameslyonsweiler.com/2018/01/31/diseases-with-unknown-etiology-trace-back-to-mass-vaccination-against-influenza-in-1976/

Patients have a right to know the specific nature of their infections, and survivors in families of those who die from respiratory infections deserve an accurate cause of death. Coroners should certainly be required to provide an accurate cause of death in so-called “flu” mortalities. Health departments should be required to count only deaths due to confirmed influenza infection as “flu” – otherwise their numbers perpetuate misperception on the risk of influenza infection, and cause fear leading to increased vaccination. How is this seen as a good thing? The population deserves good and honest doctors and stewards of public health.

HHS could demand swab results for all suspected cases of “flu deaths” with a press release and enforce them with random audits. This annual ritual of fear-mongering over “flu-deaths” hides the fact that as long as thimerosal is injected into patients, they are at increased risk of other infections. And due to heterologous immunity, even without thimerosal, flu vaccines can confuse the immune system and muddle up ineffective immune response by trying to re-purpose B-cells trained on the wrong virus, hobbling the immune system making it unresponsive to similar viruses. Such as next year’s flu strain.

We do need objectivity to arise immediately throughout the public health system in the US, starting with HHS, then to CDC and to all Health Departments around the country. Many studies have also found problems with Tamiflu. But no emergency epidemiological study is addressing the question – why are so many young people dying from “flu”? Many of the reports I’ve seen include mention that they person had not only been vaccinated, they also had taken Tamiflu. And many had taken Tylenol. It’s time to ask the tough questions. The science is there on problems with Tylenol for vaccine-induced fever, and it must be taken into consideration. Fever due to respiratory infections after flu vaccination is still vaccine-induced.

A look at the issues with Tamiflu (see primary scientific literature reviewed here) shows that we cannot ignore the possibility that the human immune system is not infinitely resilient, and that medicine’s approaches to tackling “the flu” is imprecise, not evidence-based, and self-defeating. I’m not talking about the number of antigens the human body can take; I’m talking about the amount of tweaking it can tolerate, especially given the aluminum-dense childhood vaccination schedule. The allopathic medical community would do very well to heed the studies that show that Vitamin D helps alleviate both vaccine injury and severity of viral infections. It helps resolve the unfolded protein response without killing the cells. And the science of ER stress (endoplasmic reticulum stress) shows that Thimerosal is, after all, not safe for human use. Same for aluminum.

Real Reform is Coming – It’s a Mathematical Certainty

Vaccines injure people every day, and kill people every week. Each injury and death informs family members, co-workers, and schoolmates. The flaws in vaccines, combined with misinformation campaigns on safety, fuel the fire and build the vaccine risk aware army. It’s a peaceful army, filled with individuals who are hurt so badly, they do not want others to suffer the same fate. They are altruistic. And under informed, ethical and distributed leadership, they are finding their momentum.

Vaccine safety science reform means removing those in the CDC and HHS that perpetuated the debacle as it grew to proportions that even they could no longer easily deny it. And that’s fine. Let them go. There are many excellent professionals capable of replacing them – people who have not been involved in cooking studies to alter the public’s perception of vaccine risk. People who have withstood unwarranted and unfair criticism by those who live in cowardice of reality. People who now no longer afraid to publish their views. An important question is who among my colleagues in Academic Public Health, and which doctors in Pediatric medicine are willing to #bebrave and take on a debacle as huge as a failed national immunization program? Who will stand up to the AAP and tell them they are wrong?

If you are that type of doctor, it will be easier if you trust those who have worked at this for years. Read Dr. Paul Thomas’ book, The Vaccine Friendly Plan. After the resignations, have him come and teach the entire CDC and HHS what he knows. Consider Dr. Alvin Moss’s wisdom – ask him to create a Conflicts of Interest Policy for CDC and HHS, as he has done for the rest of academic medicine. Bring in Dr. Bob Sears from California, who was willing to stare down threats of the loss of his license to practice medicine because he dared to continue to practice medicine in the face of wanton misinformation and pressure from the AAP. Consider Dr. Richard Frye, and Dr. Chris Exley from the UK, who care first and foremost about the truths that impact total health. Dr. Frye would be great as the new NIH Director, in my opinion. Let these people form a new national public health direction that overrides existing contracts. There are others. Like Dr. Judy Mikovits whose character stands much taller than those who tried – and failed – to silence her – on the issue of adventitious agents in viral vaccines (specifically and quite problematic: retroviruses). Ask Dr. Ted Fogarty about Ethical Vaccinomics, and testing for vaccine injuries. Bring in Dr. John Piesse from Australia and end his persecution there, and put his good will toward safety to work here. We would be lucky to have him.

Create a Manhattan Project focused on reducing vaccine injuries, not on making currently licensed vaccines safer. They are old, and stale, and tired, and they, too, need to go. Bring in exciting new developments in artificial immunization like microneedle patches. Bring in Dr. Kanduc to screen epitopes that are unsafe. Drop aluminum, as many have now called for, and bring in calcium carbonate – if needed at all. Let those pharmaceutical companies who created the disaster make good on their promises to stop making their vaccines. Then we will see new approaches to artificial immunization that compete on the platform of safety.

Don’t just end COIs at ACIP: End ACIP. Create a Vaccine Safety Commission that enforces Science Integrity. Open up the markets. Let ideas thrive. Let consumers choose. Let the FDA do its job. Let the people’s experiences be heard. Establish a paradigm in which the end consumer has a say in the quality of the product. Strip the CDC of the ability to hold patents. End the CDC Foundation. End the differences between drugs and biologics and require randomized clinical trials – with proper placebos, not aluminum hydroxide – for vaccines. Repeal the 1986 Act that protects drug companies from liability for faulty vaccines. Perform random spot checks of vaccines in practices for contamination. The total sum of policies in the National Immunization Program, and the burden of morbidity on the population is a serious threat to our National Security.

Let some new faces and voices drive this reform. Bring in Dr. Dan Neides who had to escape the Cleveland Clinic after speaking his conscience. Let him oversee the transition. Bring in Dr. Brian Hooker to personally issue the pink slips to those who must now go from the CDC. Let all of those named here share his or her experience with Congress. Have Dr. Thompson testify. We need truth and reconciliation. And we need it 42 years ago.

There are MDs who sit in the shadows, silent, and afraid of job loss, sanction, ridicule. Step up. Let your views be known to the current Administration. Join Physicians for Informed Consent. You are not alone. You can help be part of the solution. Attend Health Department meetings and speak up for Informed Consent. Speak up for vaccine exclusions for kids in homes with high lead levels. Speak up for spacing out vaccines and skipping them. Speak up for tolerance and understanding of the pain and anguish parents of kids with autism experience when they are told it’s genetic, they know it’s environmental, and they are told they have to vaccinate their other babies. Speak up against calling CPS for parents who want to take the time they have under the law to consider vaccinations. And, of course, do right by your patients. Listen to their concerns. Inform them of both risks and benefits, as required by Federal Regulations. Let them know they are enrolling themselves or their children (and unborn baby) in post-licensure vaccine safety clinical trials (as required by Federal Regulations). Provide medical and philosophical exemptions for school waivers as required by the laws of your state and the rule of your own conscience. The AAP does not represent the rights and will of the people of the United States of America. Our legislation does.

Let’s aim to not make 2020 vaccination look anything like 2019. We have solutions. We’re now aiming for Healthy People 2050, and the current vaccines have very little to do with our vision. By the way, these ideas don’t come (exclusively) from me. They are shared by hundreds of thousands of American citizens, many of whom have been made sick or lost loved ones to vaccines. #werenotgoingaway #releasetheothermemos #hearthiswell #notmine #Vaxxed #cdctruth #saveourbabies #bebrave #ipak #cdcwhistleblower #rfkcommission #educatebeforeyouvaccinate #vaxxed #learntherisk #wedid #cdclied #stopmandatoryvaccination #learntherisk.”

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**Comment**

More just keeps popping out of Pandora’s Box regarding vaccines.

This recent talk shows how vaccines are causing Lyme/MSIDS patients to relapse as well as worsen:  https://madisonarealymesupportgroup.com/2018/02/04/dr-muth-immune-issues-and-lyme-msids/

https://madisonarealymesupportgroup.com/2017/12/02/scottish-doctor-gives-insight-on-lyme-msids/  Scottish doctor treating a number of young women who fell ill after their HPV vaccination, which seems to have stimulated a latent Lyme infection to reactivate.

https://madisonarealymesupportgroup.com/2016/04/24/gardasil-and-bartonella/  Asymptomatic girls after receiving Gardasil activated dormant Bartonella which was confirmed by testing.

Great video on the flu vaccine’s ineffectiveness:  https://madisonarealymesupportgroup.com/2015/11/08/flu-vaccine-causes-the-flu/

I could go on and on to infinity.  Something must be done.  Be a part of the solution.

 

 

 

 

 

 

Dr. Muth – Immune Issues and Lyme/MSIDS

Published January, 2018

Dr. Debra Muth, ND, WHNP, BSNH, MSNH, ARNP, BAAHP spoke at the Madison Area Lyme Support Group  She discusses various bacterial, viral and immunological effects that activate the immune system and cause symptoms to increase, as an over active immune system can mimic Lyme/MSIDS symptoms. She believes it’s important to look at all angles of the immune system and how it affects patients.

She reviews how Marcon’s, Viruses, Heavy Metals and vaccines activate the immune system and cause increased brain inflammation. She discusses treatment options available to date, including the RK protocol and how it can assist with Lyme treatment, as well as how it fits in with treatment successes in her practice.

Vaccne and inlammation Madison Support Group 2018  Accompanying pdf

Forget Ebola, Sars and Zika: Ticks are the Next Global Health Threat

https://www.theguardian.com/science/blog/2018/jan/25/forget-ebola-sars-and-zika-ticks-are-the-next-global-health-threat

Forget Ebola, Sars and Zika: ticks are the next global health threat

Ticks carry a wide array of pathogens – and environmental changes mean they are spreading

A blacklegged tick - also known as a deer tick.

Since the beginning of our species we have been at war. It’s a continuous, neverending fight against the smallest of adversaries: armies of pathogens and parasites. As we have developed new ways to survive and stop them, they have evolved ever more complex and ingenious methods to thwart our efforts.

Humans have faced numerous attempts to challenge our dominance on planet Earth and from the Black Death to the Spanish flu, we have weathered them all. However, since the start of the 21st century, with its trend towards global interconnectedness, these onslaughts are ever-increasing. In the past 17 years we have battled Sars, the Ebola virusMers, and more recently the mysterious mosquito-borne Zika virus. These diseases seeming to appear from nowhere and rapidly ravage our populations. One commonality is that they almost always originate in animals before jumping across to people, and few parasites are as good at jumping between animals and people as the tick.

Ticks could be best described as the used syringes of the natural world due to their promiscuous feeding habits. Most ticks go through three stages in their lives and feed on a different host at each stage, whilst simultaneously collecting hitchhiking microbes in their blood meals. Ticks also have one of the widest distributions of any vector on Earth – they can be found on every continent, including frigid Antarctica. This combination of ubiquity and a bad habit for accumulating pathogenic microbes make ticks some of the most dangerous vectors on the planet.

So why ticks? And why now?

Partly, it’s because ticks have been understudied for so long that only recently have we begun to realise just how much they affect our health. It took until 1975 for the infamous Lyme disease even to be formally described, and today the list of microbes found within ticks grows ever larger every year as numerous new species are discovered.

An engorged tick removed from a host.
An engorged tick removed from a host. Photograph: Astrid860/Getty Images/iStockphoto

Changing ecosystems are also forcing ticks into closer contact with humans. Perhaps the most immediate changes are being driven by land clearing, which is forcing wildlife into closer contact with humans; with wildlife come ticks and the diseases they carry. Climate change has also been implicated: as the climate gets warmer, some ticks are expanding their ranges into places where cool winter temperatures previously limited their distribution. Geographical boundaries are also being eroded as rapid transport links environments which were previously isolated from one another. This presents easy opportunity for ticks to cross borders and spread to new habitats they may not have previously occupied.

In short, our manipulation of the environment has set the stage for a tick-driven health crisis.

Ticks can carry an extremely wide array of human pathogens, including bacteria, viruses, and protozoa. Within the long list of human ailments caused by ticks, several dangerous diseases stand out.

https://interactive.guim.co.uk/uploader/embed/2017/08/ticks_lyme_disease/giv-3902DdVd63hb2z2v/

While the recognition of Lyme disease has led to a greater study of the bacteria which cause it and more frequent testing for patients, it has been a double-edged sword, as its notoriety has overshadowed equally important diseases like tick-borne rickettsiosis (TBR). TBR is caused by a number of different bacteria distributed across the globe. Unfortunately, TBR often presents with signs and symptoms similar to Lyme disease, such as rashes, joint and muscle pain, and fatigue. Although deaths are rare when TBR is treated with antibiotics like doxycycline, when the disease is incorrectly diagnosed or adequate medical infrastructure is lacking, mortalities can still occur.

Babesiosis is an emerging tick-borne disease caused by a protozoan called Babesia, a species related to the microbe which causes malaria. The disease is rarely tested for by doctors and the global levels of human infection are unknown, although some researchers believe that they may be much higher than present rates of diagnosis indicate. Infections can be highly variable, with about a quarter of infected adults showing no signs of the disease, while others will die from the infection. In truth the disease is still poorly understood in humans, which is compounded by the fact that several species of Babesia cause the disease and the signs and symptoms can be wide-ranging and often include fever, fatigue, anaemia, and nausea – all common features of other illnesses.

The distinctive “bullseye” marking caused by a bite from a deer tick.
The distinctive “bullseye” marking caused by a bite from a deer tick. Photograph: anakopa/Getty Images/iStockphoto

Crimean-Congo haemorrhagic fever (CCHF) is perhaps the most terrifying disease spread by ticks, as there are no treatments available, and mortality rates can be as high as 40% in infected humans. To put it into perspective, that mortality rate is similar to untreated cases of Ebola or the bubonic plague. The World Health Organisation views CCHF virus as having a high chance of causing human disease epidemics and has accordingly directed considerable funding towards finding a treatment, although to date none have been developed. The wide distribution of tick vectors capable of spreading the disease coupled with the ability of common domestic animals such as sheep and cattle to maintain the CCHF virus in their blood at high levels means the potential for CCHF to expand into new regions like Europe is highly probable.

While only discovered in 2009, SFTS virus (severe fever with thrombocytopenia syndrome) has sparked widespread fear through much of Asia, especially in Japan where 57 people have died of the disease since 2013. Signs of the disease can range in severity from relatively mild, like fever and diarrhoea, to severe, which can include multiple organ failure. The fact that the epidemiology of the disease is so poorly known makes predicting and controlling its spread difficult. It is also known to be carried by at least two cosmopolitan tick species which are spread throughout the world from the UK, to the US, and even Australia. That might sounds bad enough, but things are even worse: although the disease typically gets to humans via a tick, from there it can spread to other humans or their pets and back again into ticks who feed on infected hosts.

Ticks are ubiquitous, dangerous, and are coming into ever greater contact with us. We must recognise that the next public health crisis may come from our backyards rather than a remote equatorial jungle in Africa or Asia.

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**Comment**

I’m thankful the article points out that other pathogens are involved.  For those with Lyme as well as these other pathogens (which is common), they typically have more severe cases and require longer and more extensive treatment.  

Ticks carry many viruses, and tick bites as well as vaccines can ignite dormant viruses in the body:  https://madisonarealymesupportgroup.com/2017/12/02/scottish-doctor-gives-insight-on-lyme-msids/

https://madisonarealymesupportgroup.com/2017/11/04/24514/  Many Lyme/MSIDS patients have reactivated Epstein Bar Virus (EBV).

https://madisonarealymesupportgroup.com/2018/01/16/a-strange-itch-trouble-breathing-then-anaphylactic-shock/

The Cabal still denies ticks transmit Bart; however, many feel otherwise.  This is why all the research in the world put out by the Cabal will never touch Bart.  It doesn’t fit the narrative.  The fly in the ointment is similar to sexual transmission for Lyme, the organisms have been found but there isn’t conclusive proof of transmission.  Many of these pathogens are fastidious and hard to study in a lab.  All case studies are ignored.

I’m always fascinated that Bartonella and Mycoplasma are rarely mentioned in regards to coinfections by mainstream news – as according to experts Dr. Nicholson and Dr. Breitshwerdt, they are probably the TOP coinfections with Lyme.  

More on Bartonella:  

https://www.northcarolinahealthnews.org/2013/12/05/bartonella-is-everywhere-so-why-dont-we-know-more-about-it/  Bartonella is a bacteria transmitted by fleas, ticks, animals, even spiders, but few people know about it.

https://madisonarealymesupportgroup.com/2016/01/03/bartonella-treatment/

https://madisonarealymesupportgroup.com/2017/11/03/first-report-of-bartonella-quintana-immune-reconstitution-inflammatory-syndrome-complicated-by-jarisch-herxheimer-reaction/

https://madisonarealymesupportgroup.com/2017/10/23/opthalmic-manifestations-of-bartonella-infection/

More on Myco:  https://madisonarealymesupportgroup.com/2016/02/07/mycoplasma-treatment/

https://madisonarealymesupportgroup.com/2015/08/12/connecting-dots-mycoplasma/

https://wwwnc.cdc.gov/eid/article/3/1/97-0103_article  This 1997 article even implicates Myco with Gulf War Syndrome, despite the CDC denying, denying, denying it.

https://madisonarealymesupportgroup.com/2017/08/26/interstitial-cystitis-and-lyme-disease/

 

Cure a Cold Fast – It’s Not the Flu Vaccine

Lyme/MSIDS patients have impaired immune systems due to serious bacterial and often viral and fungal infections, so when a cold or flu strikes, we are sitting ducks.  Recent research shows that just breathing is enough to spread the flu:  http://www.pnas.org/content/early/2018/01/17/1716561115  This information is being used to frighten and push the flu vaccine which Dr. Mercola explains is about 10% effective this year due to viral mismatches and growth substrates where viruses can mutate:  https://articles.mercola.com/sites/articles/archive/2017/12/19/flu-vaccine-likely-worthless.aspx

Then there’s that pesky detail of not having enough studies on the effectiveness of formaldehyde killing the virus making it “inactive” which explains why some get the flu after getting the vaccine:  http://www.thevaccinereaction.org/2018/01/formaldehyde-doesnt-always-kill-viruses/  This happened before when 40,000 kids were given the Salk IPV and got polio.  OOPS!

What authorities don’t tell you about vaccines for the immunocompromised, such as Lyme/MSIDS patients, is that a vaccine which is created to lower your immune system so that your body mounts an immune response can activate latent infections.  https://madisonarealymesupportgroup.com/2017/12/02/scottish-doctor-gives-insight-on-lyme-msids/  Within this link you will also see a connection between the HPV vaccine and Bartonella.  I just finished “Lyme Madness,” by Lori Dennis.  Her son’s Lyme/MSIDS activated after a flu shot.  I hear these stories over and over.  

And then there’s the damning retroviral connection:  https://madisonarealymesupportgroup.com/2017/10/15/vaccines-and-retroviruses-a-whistleblower-reveals-what-the-government-is-hiding/

Often the first sign of immune dysregulation is an adverse reaction to a vaccine:  https://articles.mercola.com/sites/articles/archive/2014/04/26/vaccines-adverse-reaction.aspx  All it took was a tetanus shot for engineer Eric Gladen to get major neurological symptoms.  After going on a protocol for about 6 months to remove mercury, his symptoms vanished.  This led him on a journey and gave us the documentary “Trace Amounts,” which is about mercury-based thimerosal & autism.  http://www.wnd.com/2015/04/rfk-jr-decries-holocaust-of-forced-vaccination/

https://madisonarealymesupportgroup.com/2017/09/19/autism-aluminum-adjuvant-link-corroborated/

The flu vaccine in particular often contains high amounts of thimerosal, which is 50% mercury.  Many vaccines also contain aluminum, a neurotoxin.  Research is growing on how these metals accumulate in the brain over time.  https://madisonarealymesupportgroup.com/2017/09/21/aluminum-flawed-assumptions-fueling-autoimmune-disease-and-lyme/

https://madisonarealymesupportgroup.com/2017/11/28/biological-mechanisms-of-vaccine-injury/

https://madisonarealymesupportgroup.com/2017/12/06/mechanisms-of-vaccine-injury-part-2/

http://vaxtruth.org/2012/01/aluminum-toxicity-and-a-primer-on-the-vic/  Great article on aluminum toxicity.

So rather than be frightened and reach for what seems like an easy button, this article will hopefully give you practical tools to use at home to lower your flu risk or lessen infection time.

The following video by NPR shows how viruses turn our cells into mini viral reproductive factories.

 Approx. 3.5 Min

Approx. 6 Min

In this video Dr. Axe shares his top seven remedies to cure a cold fast. These specific remedies can help you get rid of your cold in 24 hours or less.  They are most effective when taken upon initial flu/cold symptoms.

1. Echinacea

The research using Echinacea tea is not consistent. The studies that demonstrated the best effect at shortening the length of a cold occurred when you drink two to three cups of Echinacea tea per day starting on the first or second day of your cold.

2. Elderberry Syrup or Extract

In one study, elderberry syrup reduced the severity of flu symptoms and shortened their duration by about four days. Elderberry extract is also known for inducing sweating, and helps relieve congestion.
3. Vitamin C (1000mg 5x day)
A very potent antioxidant; use a natural form such as acerola, which contains associated micronutrients.  You can take several grams every hour (use the liposomal form so you don’t get loose stools), till you are better. 

4. Garlic (capsules or cloves)

In the singular study identified by the Cochrane group, those who took garlic daily for three months had fewer colds than those who took a placebo, and, when they did come down with a cold, the duration of illness was shorter — an average of 4.5 days compared to 5.5 days for the placebo group.

5. Oregano Oil/ Oil of Oregano (4-5 drops in water)
The higher the carvacrol concentration, the more effective and most active antimicrobial agent in oregano oil which has potent antibacterial and antiviral effects. In one study, researchers found when in spray form in combination with four other aromatic plants it could immediately reduce the side effects of a cold. This treatment was no longer effective after three days of use. Oil of oregano should not be used by children, women who are pregnant or nursing or who plan to become pregnant.
6. Zinc (100mg a day)
A Cochrane Database Review of the medical research on zinc found that when taken within one day of the first symptoms, zinc can cut down the time you have a cold by about 24 hours.  Zinc was also found to greatly reduce the severity of symptoms. Zinc was not recommended for anyone with an underlying health condition, like lowered immune function, asthma or chronic illness.  Dr. Mercola does not recommend taking more than 50 mg a day, and does not recommend taking zinc on a daily basis for preventive purposes as you could easily develop a copper imbalance that way.

7. Apple Cider Vinegar (2 Tbsp in water 3x a day)

Cold viruses increase the acidity of your body.  Apple Cider vinegar reduces the acidity and has acetic acid that helps prevent the growth of viruses.
Eliminate sugars from your diet, add in a real vegetable soup a day, consume chicken broth, and citrus fruits. For more information on getting rid of a cold check out this article: http://draxe.com/natural-cold-remedies/
Since it’s a fat-soluble vitamin, it can be toxic, which is why it’s important to test your level at least yearly.  It’s also more effective than the flu-vaccine:  https://articles.mercola.com/sites/articles/archive/2017/02/27/vitamin-d-better-than-flu-vaccine.aspx

https://articles.mercola.com/sites/articles/archive/2017/02/06/natural-cold-remedies.aspx  Dr. Mercola adds to this list:

1. Meditation – has significant positive effects on heart rate, brain function, stress reduction and blood pressure.  Research also has demonstrated lasting positive effects on brain function and immune system.  Imaging demonstrated an increase in activation in the left frontal region of the brain associated with lower anxiety, and blood work showed larger increases in antibody production in participants who meditated in the study. 

2. Exercise – if all symptoms are above the neck, such as sneezing, sniffling and watery eyes, then breaking out in a sweat is generally considered safe. The immune system functions better when you exercise regularly and is a good preventative measure.  Walking, jogging, yoga and slow biking are among the best exercises when you have a cold, while endurance sports, team sports, weightlifting and exercising in the cold weather are among the worst.  Exercise may help you feel better but may not shorten the length of your cold. If you are involved in strenuous exercise it depletes the energy needed to fight the virus and can actually make your symptoms worse.

3. Sleep – Sleep has a strong regulatory influence on your immune system and promotes the influence of cytokines stimulating the interaction between antigen-presenting cells and T-helper cells necessary for your body to fight virus infections.  Most people need between about eight hours of sleep a night and plenty of rest during the day.

4. Nasal Saline Rinse – Although researchers can only speculate how saline nasal washes are effective in treating and preventing virus infections and recurrences, the fact is they are effective.  Use only sterile normal saline water in the rinse.  Tap water can increase the inflammatory response in the sinus passages and carry parasites that can infect your brain.

5. Hydrogen Peroxide – In 1928, Dr. Richard Simmons hypothesized that the cold virus entered your body through the ear canal and not the nose. His theory was dismissed by the medical community; however, in 1938, German researchers had great success using hydrogen peroxide in the ear canal to treat colds and the flu.  You must start treatment in the first 24 hours to have a significant impact on reducing the length of the cold. Take a capful of hydrogen peroxide and while lying on your side, pour it in, letting it bubble for a few minutes.  Switch sides and repeat.

6. Chicken Soup – A team of researchers from the University of Nebraska Medical Center found evidence that chicken soup — both homemade and from the can — had anti-inflammatory properties that could prevent the side effects of a cold.  Avoid the canned varieties in favor of a home-cooked version with homemade broth.

9. Coconut Oil – has both antibacterial and antiviral properties.  Rub coconut oil over your skin. It is readily absorbed into your body and, as an added benefit, will soften your skin too. Add one-half teaspoon to your coffee or tea when you have a cold and cook with it.

10. Baking Soda – reduces the acidity of your body in the treatment of colds and flu. However, I have pushed the body pH in the opposite direction and achieved the same results, shortening the length of an infection.  The administration of baking soda is simple, relatively harmless and easy to test on your own cold. Simply dissolve the recommended amount of baking soda in a glass of cold water and drink it. Recommended dosages from the Arm & Hammer Company for colds and influenza back in 1925 were:

Day 1 — Take six doses of one-half teaspoon of baking soda in glass of cool water, at about two-hour intervals
Day 2 —Take four doses of one-half teaspoon of baking soda in glass of cool water, at the same intervals
Day 3 — Take two doses of one-half teaspoon of baking soda in glass of cool water morning and evening, and thereafter ½ teaspoon in glass of cool water each morning until cold symptoms are gone
This should only be used as an occasional (not chronic) treatment, however, and be careful not to consume excessive amounts, which can cause serious electrolyte and acid/base imbalances.

11. Lifestyle Choices – eliminate or drastically reduce your alcohol intake and smoking. Both of these factors negatively impact your immune system, making it more difficult for your body to fight the viral infection.

12. Steam – will not shorten the length of your cold, but it will help to break up the mucous secretions in your sinuses, reduce the inflammation in your nasal passages and help you to breathe better.

13. Stress Reduction – Practicing meditation, yoga or Emotional Freedom Techniques (EFT) are simple and effective practices to support your immune system and prevent other damage caused by stress.

14. Hand Washing – is a deterrent for infection by viruses and against further infection while you are sick. It will also reduce the spread of the virus to other family members, but it will not shorten the length of your cold. Remember that too much hand washing is almost as bad as not enough. Frequent washing strips your skin of protective oils, causing the skin to crack and bleed.

15. Eat Real Food – and avoiding processed foods will give your body the necessary tools to fight a viral infection. It will also reduce the potential you’ll suffer a quick recurrence of the infection.

https://vitalplan.com/blog/flu-alert-how-to-prep-for-a-bad-season?

In this article Dr. Rawls gives some more great advice:

  1. Isolate the sick & stay in bed
  2. Wash your hands
  3. Maintain a healthy immune system
  4. Drink lots of fluids
  5. Take Vitamin C (1,000 mg up to 4X/day)
  6. Take herbal therapy to support your immune system
  7. Apple cider vinegar (2 Tbs with 8oz water and 1-2 tsp local honey – drink several X/day)
  8. Reduce food intake
  9. Inhale steam before bed (can use essential oils in steam)
  10. Antiviral drugs can reduce severity and duration  Please see this news story first:  http://dfw.cbslocal.com/2018/01/12/unexpected-side-effects-tamiflu/

 

 

New Powassan Test – 89% Sensitive

Development and Validation of a Serologic Test Panel for Detection of Powassan Virus Infection in U.S. Patients Residing in Regions Where Lyme
Disease Is Endemic

Thomm AM, Schotthoefer AM, Dupuis AP II, Kramer LD, Frost HM, Fritsche
TR, Harrington YA, Knox KK, Kehl SC.
/mSphere/. 2018 Jan 10;3(1). pii: e00467-17. eCollection 2018 Jan-Feb.

https://doi.org/10.1128/mSphere.00467-17

Abstract

Powassan virus (POWV) is an emerging tick-borne arbovirus presenting a
public health threat in North America. POWV lineage II, also known as
deer tick virus, is the strain of the virus most frequently found in
/Ixodes scapularis/ ticks and is implicated in most cases of POWV
encephalitis in the United States. Currently, no commercial tests are
available to detect POWV exposure in tick-borne disease (TBD) patients.

We describe here the development and analytical validation of a
serologic test panel to detect POWV infections. The panel uses an
indirect enzyme immunoassay (EIA) to screen. EIA-positive samples reflex
to a laboratory-developed, POWV-specific immunofluorescence assay (IFA).

The analytical sensitivity of the test panel was 89%, and the limit of
detection was a plaque reduction neutralization test (PRNT) titer of
1:20. The analytical specificity was 100% for the IgM assay and 65% for
the IgG assay when heterologous-flavivirus-positive samples were tested.

On samples collected from regions where Lyme disease is endemic,
seroprevalence for POWV in TBD samples was 9.4% (10 of 106) versus 2%
when tested with non-TBD samples (2 of 100, /P/ = 0.034). No evidence of
POWV infection was seen in samples collected from a region where Lyme
disease was not endemic (0 of 22).

This test panel provides a sensitive and specific platform for detecting
a serologic response to POWV early in the course of infection when
neutralizing antibodies may not be detectable. Combined with clinical
history, the panel is an effective tool for identifying acute POWV
infection.

*Importance*
Approximately 100 cases of POWV disease were reported in the United
States over the past 10 years. Most cases have occurred in the Northeast
(52) and Great Lakes (45) regions
(https://www.cdc.gov/powassan/statistics.html). The prevalence of POWV
in ticks and mammals is increasing, and POWV poses an increasing threat
in a greater geographical range.

In areas of the Northeast and Midwest where Lyme disease is endemic,
POWV testing is recommended for patients with a recent tick bite,
patients with Lyme disease who have been treated with antibiotics, or
patients with a tick exposure who have tested negative for Lyme disease
or other tick-borne illnesses and have persistent symptoms consistent
with posttreatment Lyme disease. Testing could also benefit patients
with tick exposure and unexplained neurologic symptoms and chronic
fatigue syndrome (CFS) patients with known tick exposure.

Until now, diagnostic testing for Powassan virus has not been
commercially available and has been limited to patients presenting with
severe, neurologic complications. The lack of routine testing for
Powassan virus in patients with suspected tick-borne disease means that
little information is available regarding the overall prevalence of the
virus and the full spectrum of clinical symptoms associated with
infection. As /Ixodes scapularis/ is the tick vector for Powassan virus
and multiple other tick-borne pathogens, including the Lyme disease
bacterium, /Borrelia burgdorferi/, the clinical presentations and
long-term outcomes of Powassan virus infection and concurrent infection
with other tick-borne disease pathogens remain unknown.

_______________

More on Powassan:  https://madisonarealymesupportgroup.com/2017/06/28/powassan-can-kill/

https://madisonarealymesupportgroup.com/2017/05/05/powassan-another-reason-to-avoid-ticks/

https://madisonarealymesupportgroup.com/2017/05/18/powassan-and-bb-infection-in-wisconsin-and-u-s-tick-populations/

https://madisonarealymesupportgroup.com/2017/04/29/more-powassan-in-maine/

 

A Strange Itch, Trouble Breathing, Then Anaphylactic Shock

https://www.nytimes.com/2018/01/04/magazine/a-strange-itch-trouble-breathing-then-anaphylactic-shock.html?_r=1

A Strange Itch, Trouble Breathing, Then Anaphylactic Shock

By LISA SANDERS, M.D. JAN. 4, 2018

“I can’t breathe,” the woman panted, her voice a husky monotone. Her sister looked anxiously at the clerk at the triage desk at the University of Iowa hospital emergency room. The woman’s breath was rapid and coarse. Her chest heaved with the work of simply breathing. She pulled at the neck of her sweatshirt — suddenly it was too tight. She pulled it over her head and dropped it to the floor. She was naked beneath the top; she had been in bed when this attack came on.

The 54-year-old woman was helped into a wheelchair and whisked into the inner sanctum of the E.R. What followed was a blur of concerned faces, needles and medical data. Her blood pressure was dangerously low; her heart was racing. She was given epinephrine and steroids, but it was hours before she could explain what had happened that night.

She was staying at her mother’s house in rural Iowa, she told the doctors. Just as she was going to bed, she felt a sudden tingling in the palms of her hands. She recognized the sensation immediately: Twice in the past eight years, she had felt the same strange itch on her hands and sometimes her feet. Each time it was quickly followed by a terrifying sense of her throat closing.

Anaphylactic Shock

She had driven herself to her sister’s house, several miles away, and her sister drove her the rest of the way to the hospital. She opened the car window to let in the frigid winter night air. She struggled to breathe. Black spots swam before her eyes, but she willed herself not to pass out.

She had had this kind of allergic reaction twice before but never as severely. She knew from her own research that this was anaphylactic shock — a potentially deadly allergic reaction. After she got the medications, the woman’s symptoms resolved. She stayed in the hospital overnight, and when it was clear that the episode was over, she went back to her mother’s house. She made an appointment to see a local allergy specialist right away.

A Mystified Allergist

The specialist spent nearly two hours going over everything the woman had been exposed to — food, plants, toxins, anything that might have triggered this nearly fatal allergic reaction. There were no new exposures that day, nothing she hadn’t eaten or touched many times before and after this latest attack. The most common cause of severe allergic reactions in adults is food, but the allergist couldn’t identify any likely suspects. He was mystified. He asked her to share her diagnosis when she got one.

For months after returning to her home on Long Island, the woman was anxious about everything she ate, and she worried every night when she went to bed. She always kept a bottle of Benadryl and an EpiPen with her, but still she was terrified about what might happen if she was too far from a hospital the next time.

‘I Need a Nurse!’

When her next attack happened — just 10 months later — she was already in Brookhaven Memorial Hospital in East Patchogue, N.Y. She was being treated with antibiotics for a devastating case of gastroenteritis due to salmonella. Her first meal, after days of nothing but clear liquids, was beef brisket with potatoes and carrots. It smelled good, but she had no appetite. She made herself eat a few bites anyway, knowing it was her first step toward going home.

A couple of hours later, she felt a strange itch on the top of her head. She scratched reflexively. Then the recognition hit her like a slap: Not now, she thought. She grabbed the IV pole, still dripping fluids into her system, and ran out into the hallway. “I need a nurse,” she shouted. Her heart was pounding, and she knew what was coming next. Hospital staffers in scrubs descended on her. Was she having a panic attack? No, an allergy attack, she told them.

They helped her back into bed and gave her oxygen, Benadryl and steroids. “What happened?” someone asked. She told the whole story, plus something she now realized — every one of her attacks seemed to come a few hours after she ate beef. She didn’t go through this every time she had a hamburger or steak; meat was a regular and much-loved part of her diet. But she was pretty sure that she had steak — or beef brisket, this time — before each episode.

Her doctors were dubious. New food allergies — especially severe ones like hers — are uncommon in adults. This was much more likely to be an allergic response to one of the antibiotics they were giving her. The patient, though, found that theory hard to swallow. It might explain this episode, but what about the earlier ones? She hadn’t been on antibiotics then. The doctors had no answer.

Was a Tick to Blame?

A nurse had a different theory about what happened, one the patient had heard before but never believed. There was some kind of tick, the nurse told her, whose bite could make you allergic to meat. She didn’t know much about it. But, the nurse suggested, she should check it out.

The woman had been bitten by ticks before — who on Long Island hasn’t? But was it really possible for a bite to produce this crazy reaction? Indeed it was, she discovered, when she got home and began doing some research. The bite of the lone star tick — named for a white spot shaped like Texas on the arachnid’s back — could cause an allergic reaction to mammalian meat. The trigger was a sugar, identified as galactose-α-1,3-galactose and more casually known as alpha-gal, a carbohydrate found in the flesh of all nonprimate mammals.

How the tick bite triggers this allergy is not yet known. The link between the tick — whose range extends from southern Florida to Maine and as far west as Iowa — and the resulting alpha-gal allergy was first described in 2009 by Thomas Platts-Mills, a professor at the University of Virginia, who himself developed the disorder. Unlike most food allergies, in which symptoms occur within minutes of consuming the allergen, the alpha-gal reaction is delayed. The symptoms — ranging from a rash to nausea to shortness of breath and even anaphylaxis — can appear four to six hours after a meal containing meat. Stranger still, the reaction doesn’t occur after every exposure.

A Diet Changed Forever

The diagnosis of mammalian meat allergy (M.M.A.) can be confirmed with a blood test that identifies antibodies to alpha-gal. The patient contacted Diane Cymerman, an allergist she had seen years earlier for seasonal allergies. Cymerman asked her to list all the foods she consumed before her last episode in the hospital and had her blood tested for antibodies to everything on the list, down to the black pepper and parsley seasoning. And to alpha-gal.

The first results came back the following week: She had a moderate allergy to beef, but everything else was normal. The following month, the test results for alpha-gal antibodies came back. She was wildly allergic to galactose-α-1,3-galactose. Cymerman called the patient with the news. She had to avoid eating meat from mammals — and everything derived from them, including Jell-O and other foods and medications made from gelatin. Even safe foods cooked on a grill that has also been used for meat can be contaminated with enough alpha-gal to trigger a reaction.

The patient contacted the allergist back in Iowa and told him what she had. He was amazed. He had only recently heard a lecture on this phenomenon. He had never seen it before her case.

It hasn’t been easy for this Iowa transplant to give up beef and other meat that comes from mammals. Some days, she tells me, just thinking about a juicy hamburger or steak makes her stomach growl. But she remembers her terror and that long drive to the Iowa hospital and sticks to chicken, fish and vegetables.

Lisa Sanders, M.D., is a contributing writer for the magazine and the author of “Every Patient Tells a Story: Medical Mysteries and the Art of Diagnosis.” If you have a solved case to share with Dr. Sanders, write her at Lisa.Sandersmd@gmail.com.

________________

**Comment**

For more on Alpha-Gal:  http://alpha-gal.org

https://madisonarealymesupportgroup.com/2017/01/12/tick-related-red-meat-allergy-found-in-minnesota-wisconsin/

Approx. 5 Min.

Great video by Dr. Greger at nutritionfacts.org on tick bites, meat allergies, and chronic urticaria

https://madisonarealymesupportgroup.com/2016/02/05/paralysis-tick-the-immune-system/  Australian allergy specialist Sheryl van Nunen got her red meat allergy mystery solved when there was a surge in allergic reactions in the U.S. to a drug, Cetuximab, used to treat colorectal cancer developed using a mouse cell line, also containing alpha-gal.

Pause

If you haven’t read the articles on vaccines, please do.
https://madisonarealymesupportgroup.wordpress.com/2015/06/19/a-word-on-vaccines/ and https://madisonarealymesupportgroup.wordpress.com/2015/07/15/vaccines-continued/
Some vaccines used to be run through mouse brains. This is important to know as mice are one of the biggest reservoirs for borrelia, the causative agent known to cause Lyme Disease.

More damning evidence of the mouse/vaccine connection:  https://madisonarealymesupportgroup.com/2017/10/15/vaccines-and-retroviruses-a-whistleblower-reveals-what-the-government-is-hiding/