Archive for the ‘Babesia’ Category

When Babesiosis Turns Deadly

https://danielcameronmd.com/when-babesiosis-turns-deadly/

WHEN BABESIOSIS TURNS DEADLY

babesiosis-turns-deadly
In their case report “Fatal Babesiosis in an Immunocompetent Patient,” Selig and colleagues describe a 48-year-old man who died within days of being admitted to the hospital from babesiosis and yet, he didn’t have any significant risk factors for severe presentation of the illness. [1]

By Dr. Daniel Cameron

The man presented to the emergency department with fatigue, generalized weakness and intermittent subjective fevers. The symptoms had worsened over a 2-week period.

The patient also complained of headaches, vision changes, nausea, vomiting and diarrhea. And had a medical history of type 2 diabetes and intermittent asthma.

“He denied any known recent tick or animal exposures, any recent travel, or previous blood transfusions,” the authors write. 

“On arrival to the ED, the patient was tachycardic, afebrile, and normotensive,” the authors write. “A blood parasite smear returned with small ring-form parasites with 25% [red blood cells] infected, consistent with babesiosis.”

“Human babesiosis is an emerging infectious disease with a progressively rising number of cases in the Northeast over the last few decades.”

The patient was admitted to the intensive care unit and began treatment with azithromycin and atovaquone, along with doxycycline for any co-infections, such as Lyme disease.

However, the next day, the patient’s conditioned deteriorated and he required endotracheal intubation with mechanical ventilation. Several days later, he died.

“A few days following the patient’s death, babesia studies returned with PCR positive for B. microti and positive anti body findings (IgG 1:128 and IgM 1:160) confirming the babesiosis diagnosis,” the authors write.

PODCAST: Delayed onset Babesia

The authors suggest, “Clinicians should be aware that even in patients without the classic risk factors of asplenia, advanced age, and immunocompromised status for severe presentations of babesiosis, a deadly case can present.”

They noted that although their patient suffered from type 2 diabetes, an immunocompromised condition, diabetes has not previously been shown to be a significant risk factor for severe babesiosis.

25 Specialists for 3 Infections: The Realities of Tick-Borne Disease

https://www.globallymealliance.org/blog/devin-wethauser?

Devin Wethauser shares her story of fighting Lyme disease, Bartonella, and Babesia in an effort to spread awareness.

It all started with the most intense stomach ache I’ve ever had, six days before my sixteenth birthday. That was the beginning of a journey I had never imagined would become my life. My symptoms were random and involved every part of my body, which sent me to over 25 different specialists. In my senior year of college, while under the care of an integrative medicine doctor, my diagnosis of Lyme, Bartonellosis and Babesiosis was confirmed.

thumbnail_image0I have had almost every symptom in the book, but specifically for Bartonella, I have had and continue to endure headaches, pain behind the eyes, muscle pain, poor appetite, swollen glands, horrible fatigue, random fevers, tachycardia, exacerbation of anxiety and depression, and severe brain fog.

Under the care of my LLMD, I have experimented with so many treatments, which unfortunately for me, have yet to help my conditions. These treatments have included the typical ciprofloxacin, ceftriaxone, doxycycline, herbals, low dose immunotherapy, and disulfiram. I am now on a combination of dapsone, rifampin, and doxycycline.

I have also developed some difficult mental health issues that made me seek out therapy. This experience, in particular, gave me purpose in my life. I realized that being a therapist, specifically for chronically ill people, is how I take the best of me and my experiences to help others.

The disease has completely changed my life. Since I’ve been sick for over a decade, I don’t remember what it’s like to feel healthy and pain free. I learned that the path I had originally carved out for me was no longer available. I’m not able to work full time as I don’t have the energy to do so. I have also developed some difficult mental health issues that made me seek out therapy. This experience, in particular, gave me purpose in my life. I realized that being a therapist, specifically for chronically ill people, is how I take the best of me and my experiences to help others. I graduated with an undergraduate degree in entrepreneurship thinking I’ll be starting a fashion business. However, now I’m currently working on my graduate degree to become a licensed professional clinical counselor and a licensed drug and alcohol counselor.

Screen Shot 2022-08-16 at 3-05-16 PMThe advice I’d share with others is that you must recognize every single person diagnosed with tick-borne infections is going to have a completely different journey. One person will be in remission from doxy while another (me) has yet to get there after trying countless treatments. At times, hope can be fleeting, but it’s important to hang on to that small sliver. I also think it’s extremely important to seek out therapy to process, build perspective and develop tools. Having these illnesses and diseases causes grief and trauma. Using professional help to navigate all this was critical for my journey.

In addition, you will have many non-believers, including those in the medical profession. I recently went to the emergency room for low oxygen saturation. The ER doctor said “you’re too young to be on all of these medications. What kind of treatment is this for LYMES disease? I’m going to cure you tonight.” This is a perfect example of why we need GLA and other organizations to fund research for better treatments. Once there’s a better treatment that LLMD’s can use and prove it works, then we can start educating ignorant doctors like the ER doctor in my story.

To read more blogs, click here.

The above material is provided for information purposes only. The material (a) is not nor should be considered, or used as a substitute for, medical advice, diagnosis, or treatment, nor (b) does it necessarily represent endorsement by or an official position of Global Lyme Alliance, Inc. or any of its directors, officers, advisors or volunteers. Advice on the testing, treatment or care of an individual patient should be obtained through consultation with a physician who has examined that patient or is familiar with that patient’s medical history. 
GLA Contributor

Devin Wethauser

GLA Contributor

*Opinions expressed by contributors are their own. Devin is currently working as a personal stylist and shopper as she’s completing her Master’s Degree in Counseling and Psychology. In her free time, she binge-watches The Office or Seinfeld, goes fishing, or cuddles with her two Rottweilers named Mack and Biggie.

Email: dwville@gmail.com

Hottest Lyme Disease Treatment Update 2022

https://www.treatlyme.net/guide/hottest-lyme-treatment-updates-2022  Video Here (Approx. 11 Min)

Hottest Lyme Disease Treatment Updates in 2022

Marty Ross MD on Top Lyme Treatment Updates of 2022

In the video in the link above Marty Ross MD describes the latest Lyme disease treatment updates in his integrative medicine practice. For more information about the topics discussed in the video article see the following resources:

Dr. Ross’s new book, Hacking Lyme Disease: An Action Guide to Wellness, will be released by early December 2022.

Disclaimer

The ideas and recommendations on this website and in this article are for informational purposes only. For more information about this, see the sitewide Terms & Conditions.

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**Comment**

Dr. Ross discusses peptides. These are not antimicrobials but help the body in fighting off infections and restoring the issues infections cause.  Ross as well as Dr. Holtdorf is evidently having a lot of success with them.

Ross also discusses biofilm busters such as lumbrokinase, which helps improve circulation, decrease muscle pain, and improve medicine delivery deep into tissues.  Those with hypercoagulation would also do well to check it out.  

A golden nugget he discussed was the finding that cryptolepis, a drug normally given for Babesia, also has action against Lyme (in vitro – or the lab, which may not transfer over to the human body or in vivo) This study also found that black walnut, Japanese knotweed, sweet wormwood, ccat’s claw, Cistus incanus, and Chinese skullcap at 1% extracts had good activity against Bb’s stationary phase compared to control antibiotics doxycycline and cefuroxime.

Important note: The minimum inibitory concentration (MIC) values of Artemisia annua, Juglans nigra, and Uncaria tomentosa were quite high for the growing phase of Bb, despite their strong activity against the non-growing stationary phase. On the other hand, the top two active herbs, Cryptolepis and Japanese Knotweed showed strong activity against both growing Bb and non-growing stationary phase.  In subculture studies, only 1% Cryptolepis extract caused complete eradication, while doxycycline and cefuroxime and other active herbs could not eradicate B. burgdorferi stationary phase cells as many spirochetes were visible after 21-day subculture.

Ross states both herbs are helpful for Bartonella as well as diflucan/fluconazole.  My LLMD had us pulse diflucan twice a week throughout our entire treatment (5 years).  I can say with experience we herxed on this drug, often.  It is a known anti-fungal; however, Dr. Hoffman (RIP) stated he believed it did far more than that, and I tend to agree having taken it.

In contrast, the study showed that Stevia rebaudiana, Andrographis paniculata, Grapefruit seed extract, colloidal silver, monolaurin, and antimicrobial peptide LL37 had little or no activity against stationary phase B. burgdorferi A few years ago all kinds of headlines came out that stevia cured Lyme. Nothing could be further from the truth.  Per usual, if something seems too good to be true, it usually is.

Dr. Klinghardt uses a sublingual form of Hyaluronic Acid to fool the cyst forms to open and become spirochetes so they can be killed by antimicrobials.  For more on Klinghardt’s treatment:  Klinghardt Lyme Protocol.

Hyaluronic Acid is a type of sugar molecule.  Many other Lyme literate doctors also use forms of sugar such as Stevia or Erythritol as “cyst busters,” in their treatment regimens.  Look for reputable sources of Erythritol as it is most commonly made with GMO cornstarch.

For more:

Anaplasma, Babesia odocoilei, and Lyme in Ticks – Found Widely Across Eastern Canada

https://www.jelsciences.com/articles/jbres1586.pdf

Tick-Borne Pathogens Anaplasma phagocytophilum, Babesia odocoilei, and Borrelia burgdorferi Sensu Lato in Blacklegged Ticks Widespread across Eastern Canada

John D Scott1 *, Elena McGoey2 and Risa R Pesapane2,3*

Corresponding author(s) John D Scott, Upper Grand Tick Centre, 365 St. David Street South, Fergus, Ontario N1M 2L7, Canada E-mail: jkscott@bserv.com DOI: 10.37871/jbres1586 Submitted: 13 October 2022 Accepted: 26 October 2022 Published: 27 October 2022 Copyright: © 2022 Scott JD, et al. Distributed under Creative Commons CC-BY 4.0

Abstract

Blacklegged ticks, Ixodes scapularis, can transmit single or multiple infections during a tick bite. These tick-borne, zoonotic infections can become chronic and cause insidious diseases in patients.

In the present tick-pathogen study, 138 (48.9%) of 282 ticks collected from 17 sites in 6 geographic area in eastern Canada harbored various combinations of Borrelia burgdorferi sensu lato (Lyme disease), Anaplasma phagocytophilum (human anaplasmosis), and Babesia spp. (human babesiosis). Overall, 167 microbial infections were detected and, of these, 25 ticks had co-infections and two ticks had polymicrobial infections.

  • the prevalence of Babesia spp. was 15.2%
  • the ratio of Babesia odocoilei to Babesia microti was 41 to 1 with this sole B. microti being detected in Nova Scotia
  • we provide the first documentation of B. odocoilei in the Maritimes
  • Eastern Ontario had an infection prevalence for B. odocoilei of 25%―the highest among the areas surveyed in this study
  • the predominant Babesia sp. was B. odocoilei

Based on our findings, health-care practitioners need to recognize that I. scapularis ticks removed from patients may be carrying multiple tick-borne pathogens.  (See link for article)

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For more:

  • https://madisonarealymesupportgroup.com/2021/05/28/study-shows-babesia-odocoilei-is-pathogenic-to-humans/  Study found B. odocoilei in two of 19 participants. DNA amplicons from these two patients are almost identical matches with the type strains of B. odocoilei in GenBank. In addition, the same two human subjects had the hallmark symptoms of human babesiosis, including night sweats, chills, fevers, and profound fatigue. Based on symptoms and molecular identification, we provide substantive evidence that B. odocoilei is pathogenic to humans. Dataset reveals that B. odocoilei serologically cross-reacts with Babesia duncani.

9 EpiPens in a Month: The Burden of Lyme, AGS, & More

https://www.lymedisease.org/9-epi-pen-a-month-mccord/

“Nine EpiPens in a month.” The burdens of Lyme, AGS, and more.

Cortney McCord delivered the following public comment at the Oct. 25 meeting of the federal Tick-Borne Disease Working Group.

I’m Cortney McCord, a registered nurse from Tupelo, Mississippi. Since May 8, 2021, I have been in a battle for my life against alpha-gal syndrome, Lyme borreliosis, bartonellosis, babesiosis, and mast cell activation syndrome.

I developed the most severe clinical presentation of alpha-gal syndrome: I react to airborne and contact exposures as well as dietary exposures to alpha-gal.

For me, it’s way more than just a meat allergy.

In January 2022, my infectious burden grew after I contracted COVID. COVID sent me into full-blown mast cell activation syndrome and made asthma and chronic urticaria a part of my daily life.

After being gaslighted by a local allergist who was ignorant of mast cell activation syndrome and airborne alpha-gal reactions, I made an appointment with expert allergist and former Working Group member Dr. Scott Commins. I am thankful to have him in my corner even if it takes a 12-hour drive to see him..

Patients like me do not have the luxury of time to sift through a myriad of ignorant doctors to find someone familiar with their condition. Because symptoms of tick-borne infections, alpha-gal syndrome, and mast cell activation syndrome are manifested in every organ system, physicians in every medical discipline should be literate in these conditions. Nobody deserves to be gaslighted because of a lack of physician education.

Another tick bite

I was bitten by another larval lone star tick at the end of this past August. In September alone, I had to use nine EpiPens. All of this from a tick the size of a speck of dirt.

In addition to long Lyme, I believe I have long COVID complicating my clinical picture.

Long COVID and long Lyme are very similar. Both Sars-CoV-2 and Borrelia burgdorferi are persistent in tissues. Both affect the host’s immune system. Both can cause mast cell activation syndrome. The medical world has no problem saying that COVID is a persistent “long” disease. Why is that not the case for persistent ‘long” Lyme borreliosis? There are stacks of good science supporting persistent “long” Lyme infection–some of which was done by current working group member Dr. Monica Embers.

I refuse to believe that this is the best that our medical and scientific community can do. Testing for both mast cell activation syndrome and tick-borne diseases is abysmal. That has to change. There should be a law requiring alpha-gal to be listed as a major allergen on every medicine, food, and consumable product that Americans have contact with. We need the Tick-borne Disease Working Group to continue in perpetuity because tick-borne conditions will affect more and more Americans as our planet warms.

Please help me. Ask Congress to address these needs. Thank you.

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**Comment**

This is truly a complicated case, but most are in my experience.

While all patients deserve to be heard and treated properly, throwing yet more money at the TBDWG which is filled with people who do not believe in chronic infection, and which has done ZERO to help  patients is not helpful.  IF, and I mean IF any money is appropriated to study this, IMO – whoever is doing the work needs needs to be independently funded.  Researchers can not be the regular cast of characters – receiving grants from corrupt public health agencies, that is literally a Cabal regurgitating old, outdated, highly myopic work which is designed for a pre-determined outcome and completely ignores a huge subset of people.

Unfortunately many patients and even advocates are oblivious to the sordid backstory of the corrupt agencies controlling research and funding.  Insanity truly is doing the same thing over and over and expecting different results.  Time to ditch the public health monopoly and public health agencies controlling research, funding, doctors, testing, treatments, and “vaccines.”

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