Archive for the ‘Mast Cell Activation Syndrome (MCAS)’ Category

9 EpiPens in a Month: The Burden of Lyme, AGS, & More

“Nine EpiPens in a month.” The burdens of Lyme, AGS, and more.

Cortney McCord delivered the following public comment at the Oct. 25 meeting of the federal Tick-Borne Disease Working Group.

I’m Cortney McCord, a registered nurse from Tupelo, Mississippi. Since May 8, 2021, I have been in a battle for my life against alpha-gal syndrome, Lyme borreliosis, bartonellosis, babesiosis, and mast cell activation syndrome.

I developed the most severe clinical presentation of alpha-gal syndrome: I react to airborne and contact exposures as well as dietary exposures to alpha-gal.

For me, it’s way more than just a meat allergy.

In January 2022, my infectious burden grew after I contracted COVID. COVID sent me into full-blown mast cell activation syndrome and made asthma and chronic urticaria a part of my daily life.

After being gaslighted by a local allergist who was ignorant of mast cell activation syndrome and airborne alpha-gal reactions, I made an appointment with expert allergist and former Working Group member Dr. Scott Commins. I am thankful to have him in my corner even if it takes a 12-hour drive to see him..

Patients like me do not have the luxury of time to sift through a myriad of ignorant doctors to find someone familiar with their condition. Because symptoms of tick-borne infections, alpha-gal syndrome, and mast cell activation syndrome are manifested in every organ system, physicians in every medical discipline should be literate in these conditions. Nobody deserves to be gaslighted because of a lack of physician education.

Another tick bite

I was bitten by another larval lone star tick at the end of this past August. In September alone, I had to use nine EpiPens. All of this from a tick the size of a speck of dirt.

In addition to long Lyme, I believe I have long COVID complicating my clinical picture.

Long COVID and long Lyme are very similar. Both Sars-CoV-2 and Borrelia burgdorferi are persistent in tissues. Both affect the host’s immune system. Both can cause mast cell activation syndrome. The medical world has no problem saying that COVID is a persistent “long” disease. Why is that not the case for persistent ‘long” Lyme borreliosis? There are stacks of good science supporting persistent “long” Lyme infection–some of which was done by current working group member Dr. Monica Embers.

I refuse to believe that this is the best that our medical and scientific community can do. Testing for both mast cell activation syndrome and tick-borne diseases is abysmal. That has to change. There should be a law requiring alpha-gal to be listed as a major allergen on every medicine, food, and consumable product that Americans have contact with. We need the Tick-borne Disease Working Group to continue in perpetuity because tick-borne conditions will affect more and more Americans as our planet warms.

Please help me. Ask Congress to address these needs. Thank you.



This is truly a complicated case, but most are in my experience.

While all patients deserve to be heard and treated properly, throwing yet more money at the TBDWG which is filled with people who do not believe in chronic infection, and which has done ZERO to help  patients is not helpful.  IF, and I mean IF any money is appropriated to study this, IMO – whoever is doing the work needs needs to be independently funded.  Researchers can not be the regular cast of characters – receiving grants from corrupt public health agencies, that is literally a Cabal regurgitating old, outdated, highly myopic work which is designed for a pre-determined outcome and completely ignores a huge subset of people.

Unfortunately many patients and even advocates are oblivious to the sordid backstory of the corrupt agencies controlling research and funding.  Insanity truly is doing the same thing over and over and expecting different results.  Time to ditch the public health monopoly and public health agencies controlling research, funding, doctors, testing, treatments, and “vaccines.”

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Ask A Lyme Doctor: Q & A With Dr. Tania Dempsey

Dr. Tania Dempsey is an expert in chronic disease, autoimmune disorders and mast cell activation syndrome. In this blog, she is answering Lyme related questions that GLA followers submitted via social media.
Are you seeing cases where Covid has re-activated Lyme or ignited new auto-immune diseases or mast cell activation syndrome? -Kimberly H.

We are just at the beginning of really understanding how COVID interacts with our immune system. Since there are few studies that have been published that give us complete clarity on this, much of what I discuss is based on my experience with my patients. What seems clear to me is there is often some sort of vulnerability or predisposition in the patient, like an autoimmune potential, underlying dysfunctional mast cells, or a history of chronic infections, that leads to the complications that we are seeing post-COVID. I have not yet seen post-COVID patients who did not have some hint of an underlying issue prior to COVID. I have patients who have a history of Lyme disease that is well controlled for a number of years but after COVID they see a recurrence in the symptoms that pre-dated their Lyme treatment. Some of these patients have new symptoms and I postulate that it could be related to their underlying old infection that reactivated in a new location in their body or the new symptoms represent a worsening of their immune dysfunction. COVID seems to both stimulate and suppress the immune system, depending on the timing of the infection and on the susceptibility of the person. If the patient has a history of Lyme disease that is chronic/persistent, we know that their immune system continues to be affected. The vast majority of Chronic Lyme patients (in my practice) have underlying dysfunction of their mast cells, even if they have not been formally diagnosed with mast cell activation syndrome. Many of them had a predisposition before being infected with Lyme, which was worsened by the infection. Since infections of various kinds are known to trigger mast cells, chronic infection can cause chronic mast cell activation that then can be triggered further by a new infection, such as COVID. The relationship between mast cells and other immune cells has been well described and MCAS can be a driver of the development of autoimmunity.

How should I deal with post Lyme flare ups? -Debra C.

There are three main scenarios that I see as contributors for “post-Lyme flares”.

  1. Mast Cell Activation Syndrome (MCAS) is a leading culprit for increased symptoms after Lyme treatment. Whether there is underlying primary MCAS or secondary MCAS triggered by the infection, mast cells often continue to be dysfunctional even after the infection is cleared. Mast Cell Targeted Therapy can be very helpful in stabilizing mast cells, minimizing mediator release and thereby minimizing inflammation.
  2. Another important possibility to consider when patients have flares of symptoms after treatment for Lyme, is the presence of “co-infections.” Treating Lyme can make room for other infections to reactivate, like viruses (EBV, HHV-6, etc), Babesia, Bartonella, and many other microbes. It is important to look for other infections while treating Lyme, so as to not miss the need for other types of treatment.
  3. Persister Lyme is a major cause of  “Post-Lyme flares.” The bacteria that causes Lyme, Borrelia Burgdorferi, can exist in a slow-growing, persister form that is resistant to antibiotics and other anti-microbial treatment. Even aggressive treatment for Lyme disease can leave behind these persister organisms that can continue to wreak havoc on the body.
What are the best current treatment for “stubborn” Bartonella? -Deb T.

Bartonella is probably one of the most difficult chronic infections that I’ve had to treat in my practice. It is necessary to use a multi-pronged approach in treatment of Bartonella. Some patients have other co-infections, which complicates the treatment as well. While I don’t think there is a “best” treatment for Bartonella yet, in my practice what I have found helpful is a combination of modalities, which could include SOT therapy (Supportive Oligonucleotide Technique), Ozone therapy, Herbal protocols and/or Antibiotics, and other therapies.

GLA is currently fundraising for The Bartonella Discovery Program, a research project bringing together some of the top researchers world-wide who are experts on Bartonellosis. These researchers will learn more about the bacteria and which treatments are most likely to cure patients.

How do you heal the nervous system after neurological Lyme and Bartonella ravage it? -Katie M.

Healing the nervous system after Lyme, Bartonella or other infections is a complicated process.  Reducing inflammation, not just by treating the infections, but also by targeting the immune cells that can continue to cause inflammation, is key. We have a considerable amount of evidence that mast cells in the central nervous system are in constant communication with other immune cells like astrocytes and microglial cells and together can be a major driver of neuroinflammation. There is no cure for neuroinflammation but there are a vast number of drugs and natural treatments that have been studied and some show promise in reducing the neuroinflammatory process. Some strategies include mast cell targeted therapy, treatment with natural compounds such as proresolving mediators (SPMs), PEA (palmitoylethinolamide), resveratrol, turmeric, and others, and various drugs like low-dose naltrexone, minocycline, NSAIDS, and steroids. Treatment needs to be individualized and other confounding medical conditions should be taken into account when choosing a protocol against neuroinflammation.

The above material is provided for information purposes only. The material (a) is not nor should be considered, or used as a substitute for, medical advice, diagnosis, or treatment, nor (b) does it necessarily represent endorsement by or an official position of Global Lyme Alliance, Inc. or any of its directors, officers, advisors or volunteers. Advice on the testing, treatment or care of an individual patient should be obtained through consultation with a physician who has examined that patient or is familiar with that patient’s medical history.
GLA Contributor

Dr. Tania Dempsey

GLA Contributor

*Opinions expressed by contributors are their own. Dr. Tania Dempsey is an expert in chronic disease, autoimmune disorders and mast cell activation syndrome. She received her MD from The Johns Hopkins University School of Medicine and her BS degree from Cornell University. Dr. Dempsey completed her Residency at NYU Medical Center/ Bellevue Hospital. She is Board Certified in Internal Medicine and a Diplomate of the American Board of Integrative and Holistic Medicine. Dr. Dempsey opened the AIM Center for Personalized Medicine, where she currently practices.


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When Parents are Unjustly Accused of Harming Their Sick Child

TOUCHED BY LYME: When parents are unjustly accused of harming their sick child

If your child has chronic Lyme disease, PANS/PANDAS, mast cell activation syndrome, POTS, or any number of other “medically complex conditions” – you have probably experienced being disbelieved by many people.

You may be a decent, well-intentioned parent doing everything you can to figure out your child’s puzzling medical problems.

You may scour the internet to learn more about the child’s condition, track the ups and downs of his or her symptoms, and carry binders full of medical records to appointments with various specialists—many of them far from your home.

But, in a cruelly ironic twist, those very activities can get you in trouble.

Physicians who have little experience with your child’s medically complex condition may feel you are “overmedicalizing” your child.

School officials may think you’re intentionally keeping your child out of class for reasons they consider invalid.

Neighbors and even family members may believe you’re exaggerating your child’s health problems—and, in their opinion, going about things the wrong way.

And, unfortunately, any one of these people might report you to Child Protection Services. And then your problems will escalate dramatically.

Now, it goes without saying that sometimes children ARE abused by parents, and there is, of course, a legitimate role for CPS investigations.

But medically complex conditions are fraught with issues that can unfairly entangle parents—and the more they fight to free themselves, the more tied up in legal knots they may become.

For an idea of how bad things can get, consider what happened to then-teenager Justina Pelletier and her family. In 2013, her parents lost custody of their daughter after Boston Children’s Hospital disagreed with how she was being treated at a different medical center. (Read more about Justina’s situation here.)

What to do?

Beth Alison Maloney, Attorney/Author

According to Beth Alison Maloney, there are things you can do now to minimize the possibility of running afoul of CPS in the future. And, if you’re already caught up in the system, there are things you can do to get out of it.

Her thorough and well-researched advice on this subject is laid out in a new book called Protecting Your Child from the Child Protection System.

Maloney is an attorney and the mother of a child who suffered from the strep-caused autoimmune condition known as PANDAS—back before practically anybody even knew what that was.

Theirs was a complicated journey. But her son finally got better and now is a well-functioning adult. She wrote their family’s story in her 2009 book, Saving Sammy: Curing the Boy Who Caught OCD.

In 2013, she wrote another instructive book, called Childhood Interrupted: The Complete Guide to PANDAS and PANS. It primarily focuses on the medical information you need to help your child recover from these conditions.

Over the past two decades, Maloney has worked as a lawyer, guardian ad litem, and nationwide consultant in the field of child protection laws. She has seen firsthand how innocent families are sometimes presumed guilty of all manner of abuse. She has seen the rise of “child abuse pediatricians”–specialists that she believes sometimes jump to unwarranted conclusions, to the detriment of the families involved.

She wrote this book so parents of sick children can understand what they are potentially up against and how they can help themselves. As she states in the introduction, “Too much is at stake for you to plunge in without being informed.”

(Please go to top link for an excerpt from the book)

Maloney’s book is divided into six parts:

  1. An overview of the Child Protection System and how it functions.
  2. How to navigate the maze and what to do if you find yourself accused
  3. The special challenges facing parents of medically complex children
  4. Building a team—lawyer, family, friends
  5. A deeper dive into the court system
  6. Rebuilding your lives after being falsely accused of abusing your child.

No parent wants to think about the possibility of losing custody of their child–especially when that child is seriously ill. But parents of medically complex children should familiarize themselves with the issues involved and take steps to head off trouble.

Knowledge is power. And if you’re falsely accused of abusing your child, you need all the power you can get.

For more information, see Beth Alison Maloney’s website.

TOUCHED BY LYME is written by Dorothy Kupcha Leland,’s Vice-president and Director of Communications. She is co-author of When Your Child Has Lyme Disease: A Parent’s Survival Guide. Contact her at



Very important information within this article, and book.  I highly advise any parent, grandparent, or concerned person who knows of a family struggling with Lyme to get this book to be educated. This is a wonderful resource and would make an excellent gift as well.

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What Can Chronic Lyme Disease Teach Us About Long COVID?

What can chronic Lyme disease teach us about long COVID?

By Daniel Kinderlehrer, MD

One-third of patients who were sick with COVID-19 have come down with chronic symptoms, now known as long COVID or long hauler syndrome or post-COVID syndrome.1

For the most part, these are people who had mild SARS-CoV-2 infections. And although vaccinations mostly protect patients from serious illness and death, recent data suggests that breakthrough cases of vaccinated people who catch the virus are at the same risk of developing long COVID as the unvaccinated.2 As yet, we don’t have data on the Omicron variant and long COVID.

Distressingly familiar symptoms

The symptoms of long COVID are distressingly familiar to patients who suffer from persistent illness with Lyme disease: severe fatigue, muscle aches and joint pains, impaired cognition (“brain fog”), insomnia, headaches, sleep disorders, cough and shortness of breath, palpitations and lightheadedness.3,4 Many patients have also reported mood issues with anxiety, depression, and even psychosis.3-5

Like the condition we call chronic Lyme, long COVID can be totally disabling, with people exhausted or short of breath after walking across the room. Sometimes these symptoms last a few months, but some folks are still ill for over a year without respite. There are now reported suicides among those who were suffering from long COVID.6

Those of us who are treating patients with chronic tick-borne infections witness these same symptoms every day in our patients. It is likely that these disorders have similar pathogenesis.

In patients with chronic Lyme, the issue is not microbes invading tissue, the way we imagine a strep throat or a wound infection, essentially disrupting cellular hardware.

Chaos in the immune system

Instead, these patients have a software or regulatory problem. Chaos in the immune system leads to immune suppression, autoimmunity and systemic inflammation;7,8 hormonal imbalances lead to fatigue and decreased resistance to infection;9 disorders of the nervous system results in impaired cognition, sleep disorders, and neuropsychiatric symptoms.10

No matter the cause, chronic inflammation has severe consequences. It often results in dysautonomia: disorder in the autonomic nervous system (ANS). In a healthy individual, the ANS employs the sympathetic arm (mostly stimulatory), with the parasympathetic (calming), to keep us well-balanced, in homeostasis.

But when the ANS is inflamed and out of balance, the result is fluctuations in pulse and blood pressure—with palpitations, lightheadedness and passing out. Dysautonomia can also trigger a myriad of other symptoms including shortness of breath, heat and cold intolerance, sweats and anxiety.11

Further downstream effects of systemic inflammation manifest as sensitivity syndromes, particularly to foods and mold. Mast cells are primitive white blood cells that evolved to protect our mucous membranes from invasion. When they become trigger-happy, they discharge histamine and a squadron of other inflammatory mediators called cytokines.

Mast cells

This is called mast cell activation syndrome. MCAS causes an array of symptoms including hives, flushing, itching, swelling, headaches, brain fog and pain syndromes. The cytokines released by MCAS stimulate the vagus nerve (the tenth cranial nerve), which can worsen symptoms of dysautonomia, impair cognition, and trigger neuropsychiatric symptoms, gastrointestinal syndromes, and breathing problems.12

And compounding the felony, the vagus nerve can further trigger mast cells to degranulate and release their inflammatory messengers.13 It’s a self-perpetuating cycle that leads to even more inflammation, disabling symptoms, and disability.

Patients with chronic Lyme frequently have endocrine issues. The most common are dysregulation of the adrenal glands and abnormal thyroid metabolism. Not only will these contribute to fatigue, but also to immune suppression.14,15

Meanwhile, immune suppression can result in activation of previously dormant viral infections like Epstein-Barr virus, which in turn contributes to fatigue, pain and inflammation.16

In addition, chronic inflammation and infection can result in hyperviscosity issues, in which “thick blood” slows circulation, reducing delivery of oxygen and nutrients to cells.17

Finally, chronic inflammation results in oxidative stress, in which highly reactive molecules called free radicals interfere with normal metabolism, like mitochondrial function.18 Mitochondria are the energy producing organelles in each of our cells, and mitochondrial dysfunction can result in debilitating fatigue.

These same issues are present in the unfortunate thousands of people suffering from long COVID.

Similarities between chronic Lyme and long COVID

In its acute stages, SARS-CoV-2 can invade tissues and cause life-threatening organ damage. But in its chronic stage, the pathophysiology appears similar to chronic Lyme—targeting software, not hardware. The result is pandemonium in our regulatory systems, with immune, endocrine, and nervous system dysfunction, and all the downstream issues associated with chronic inflammation.

As with patients with chronic Lyme, those with long COVID suffer from autoimmune inflammation. Antibodies to SARS-CoV-2 cross-react with multiple tissues including the gut, lung, heart and brain.19 There are now reports of SARS-CoV-2 infection resulting in PANS, Pediatric Acute-onset Neuropsychiatric Syndrome—autoimmune inflammation of the brain resulting in severe mood and behavioral symptoms in children and adolescents.20

According to most clinical descriptions of long COVID patients, the majority suffer from severe dysautonomia, with wild fluctuations in pulse and blood pressure.21 In addition, many patients have evidence of adrenal insufficiency and thyroid dysregulation, with elevations in thyroid antibodies and increased reverse T3.22-24

And, consistent with their excess inflammation and hyperreactive state, many long COVID patients have developed food sensitivities and suffer from excessive mast cell activation.25 And no surprise, SARS-CoV-2 infection creates oxidative stress that impairs mitochondrial function.26

SARS-CoV-2 can also result in hyperviscosity syndromes, sometimes severe enough to require anticoagulation.27

Latent viruses re-emerge

As with chronic Lyme, immune dysregulation promoted by SARS-CoV-2 infection can result in reactivation of latent viruses. Researchers in the United States and Turkey found that two-thirds of patients with long COVID had a reactivated Epstein-Barr virus infection compared to only 10% of controls.28

Here is something to think about: How many patients with long COVID actually have chronic Lyme that was activated by the viral insult? This has been reported to me by my colleagues. The two microbes most associated with this activation phenomenon are Bartonella and Mycoplasma, both capable of causing serious autoimmune problems.29,30 And some folks suffering from chronic Lyme have relapsed after getting COVID-19.

In other words, it’s complicated. Inflammation is widespread and there are imbalances throughout the body. There is no single intervention that can heal those who suffer from long COVID.

Medical detective work needed

Long COVID patients require careful medical detective work that uncovers the underlying imbalances. Interventions include decreasing inflammation; normalizing endocrine function; stabilizing the autonomic nervous system; supporting mitochondrial function; uncovering sensitivity syndromes; addressing mast cell activation syndrome and vagal nerve dysfunction; and treating reactivated infections.

One more thought. It is now clear that some patients with long COVID improve when they are vaccinated.31 This suggests that these folks may still have active infection with the corona virus. We know that SARS-CoV-2 has the capacity to disable and evade the immune response,32 and some patients do not successfully clear the virus over long periods of time.33,34

As we learn more, it may be appropriate to treat persistent SARS-CoV-2 infection in patients with long COVID with anti-viral drugs that are now becoming available. While the Infectious Disease Society of America maintains otherwise, there is a wealth of data and clinical experience that antibiotics are effective in treating patients with chronic Lyme.33

The good news is that we have been largely successful treating our patients with chronic Lyme. Ninety percent of my patients get 80 to 100% better, even after being ill for years. It’s a careful process that involves detective work, trial and error, curiosity and determination. Let’s hope the same is true for those with long COVID.

Dr. Daniel Kinderlehrer is an internal medicine physician in Denver, Colorado, with a practice devoted to treating patients with tick-borne illness. He is the author of  Recovery From Lyme Disease: The Integrative Medicine Guide to the Diagnosis and Treatment of Tick-Borne Illness.


  1. Logue JK, Franko NM, McCulloch DJ, et al. Sequelae in Adults at 6 Months After COVID-19 Infection. JAMA Netw Open.2021;4(2):e210830.
  2. (Accessed November 9, 2021)
  3.,within%20a%20few%20weeks. (Accessed November 30, 2021)
  4. Taquet M, Dercon Q, Luciano S, Geddes JR, Husain M, Harrison PJ. Incidence, co-occurrence, and evolution of long-COVID features: A 6-month retrospective cohort study of 273,618 survivors of COVID-19. PLoS Med. 2021;18(9):e1003773. doi:10.1371/journal.pmed.1003773
  5. Varatharaj A, Thomas N, Ellul MA, et al. Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study [published correction appears in Lancet Psychiatry. 2020 Jul 14;:]. Lancet Psychiatry. 2020;7(10):875-882. doi:10.1016/S2215-0366(20)30287-X
  6. Sher L. Post-COVID syndrome and suicide risk. QJM. 2021;114(2):95-98. doi:10.1093/qjmed/hcab007
  7. Singh SK, Girschick HJ. Lyme borreliosis: from infection to autoimmunity. Clin Microbiol Infect. 2004;10(7):598-614. doi:10.1111/j.1469-0691.2004.00895.x
  8. Lochhead RB, Strle K, Arvikar SL, Weis JJ, Steere AC. Lyme arthritis: linking infection, inflammation and autoimmunity. Nat Rev Rheumatol. 2021;17(8):449-461. doi:10.1038/s41584-021-00648-5
  9. Silverman MN, Heim CM, Nater UM, Marques AH, Sternberg EM. Neuroendocrine and immune contributors to fatigue. PM R. 2010;2(5):338-346. doi:10.1016/j.pmrj.2010.04.008
  10. Pegah Touradji, John N Aucott, Ting Yang, Alison W Rebman, Kathleen T Bechtold, Cognitive Decline in Post-treatment Lyme Disease Syndrome, Arch Clin Neuropsychol. 2019;34(4):455–465,
  11. (Accessed November 30, 2021)
  12. Aken C. Mast cell activation syndromes. J Allergy Clin Immunol. 2017;140:349-55.
  13. Stead RH, Colley EC, Wang B, et al. Vagal influences over mast cells. Auton Neurosci. 2006;125(1-2):53-61. doi:10.1016/j.autneu.2006.01.002
  14. Bancos I, Hazeldine J, Chortis V, et al. Primary adrenal insufficiency is associated with impaired natural killer cell function: a potential link to increased mortality. Eur J Endocrinol. 2017;176(4):471-480. doi:10.1530/EJE-16-0969
  15. Schoenfeld PS, Myers JW, Myers L, LaRocque JC. Suppression of cell-mediated immunity in hypothyroidism. South Med J. 1995;88(3):347–349.
  16. Koester TM, Meece JK, Fritsche TR, Frost HM. Infectious Mononucleosis and Lyme Disease as Confounding Diagnoses: A Report of 2 Cases. Clin Med Res. 2018;16(3-4):66-68.
  17. Sloop GD, De Mast Q, Pop G, Weidman JJ, St Cyr JA. The Role of Blood Viscosity in Infectious Diseases. Cureus. 2020;12(2):e7090.
  18. Peacock BN, Gherezghiher TB, Hilario JD, Kellermann GH. New insights into Lyme disease. Redox Biol. 2015;5:66-70.
  19. Taefehshokr N, Taefehshokr S, Hemmat N, Heit, B. Covid-19: perspectives on innate immune evasion.  Immunol.2020;11:580641.
  20. Pavone P, Ceccarelli M, Marino S, Caruso D, Falsaperla R, Berretta M, Rullo EV, Nunnari G. SARS-CoV-2 related paediatric acute-onset neuropsychiatric syndrome. Lancet Child Adolesc Health. 2021 Jun;5(6):e19-e21.
  21. Barizien, N., Le Guen, M., Russel, S. et al.Clinical characterization of dysautonomia in long COVID-19 patients. Sci Rep. 2021;11:14042.
  22. Akbas MA, Akbas N. Adrenal Insufficiency in the Covid-19 Era. Am J Physiol Endocrinol Metab 320: E784–E785, 2021.
  23. Lui DTW, Lee CH, Chow WS, et al. Long COVID in Patients With Mild to Moderate Disease: Do Thyroid Function and Autoimmunity Play a Role?. Endocr Pract. 2021;27(9):894-902.
  24. Khoo B, Tan T, Clarke SA, et al. Thyroid Function Before, During, and After COVID-19, J Clin Endocrinol Metab. 2021;106(2):e803-e811.
  25. Afrin LB, Weinstock LB, Molderings GJ. Covid-19 hyperinflammation and post-Covid-19 illness may be rooted in mast cell activation syndrome. Int J Infect Dis. 2020 Nov;100:327-332.
  26. Wood E, Hall KH, Tate W. Role of mitochondria, oxidative stress and the response to antioxidants in myalgic encephalomyelitis/chronic fatigue syndrome: A possible approach to SARS-CoV-2 ‘long-haulers’?.Chronic Dis Transl Med. 2021;7(1):14-26.
  27. Maier CL, Truong AD, Auld SC, Polly DM, Tanksley CL, Duncan A. COVID-19-associated hyperviscosity: a link between inflammation and thrombophilia?. Lancet. 2020;395(10239):1758-1759.
  28. Gold JE, Okyay RA, Licht WE, Hurley DJ. Investigation of Long COVID Prevalence and Its Relationship to Epstein-Barr Virus Reactivation. Pathogens. 2021;10(6):763.
  29. Kinderlehrer DA. Is Bartonella a Cause of Primary Sclerosing Cholangitis? A Case Study. Gastrointest Disord. 2020;2(1):48-57.
  30. Biberfeld G. Autoimmune reactions associated with Mycoplasma pneumoniae infection. Zentralbl Bakteriol Orig A. 1979;245(1-2):144-149.
  31. (Accessed January 21, 2022)
  32. Taefehshokr N, Taefehshokr S, Hemmat N, Heit, B. Covid-19: perspectives on innate immune evasion.  Immunol.2020;11:580641.
  33. Vibholm LK, Nielsen SSF, Pahus MH, et al. SARS-CoV-2 persistence is associated with antigen-specific CD8 T-cell responses. EBioMedicine. 2021;64:103230.
  34. Sun J, Xiao J, Sun R, et al. Prolonged Persistence of SARS-CoV-2 RNA in Body Fluids. Emerg Infect Dis. 2020;26(8):1834-1838.
  35. Kinderlehrer, D.A. Recovery From Lyme Disease: The Integrative Medicine Guide to Diagnosing and Treating Tick-Borne Illness, Skyhorse Publishing, 2021, p.15-30.


Go here to read about a Lyme patient’s journey with COVID.

I beg you to do your homework before agreeing to be a lab rat in an ongoing experiment. Lyme/MSIDS patients are disadvantaged as their bodies are already fighting an epic war. Adding an experimental, fast-tracked, gene therapy injection that doesn’t protect you from getting COVID or stop you from transmitting it is questionable at best and unbelievably dangerous at worst. Further, it’s been proven time and time again that natural immunity is far superior to an injection that only works on certain variants, and poorly at that.

And of course, the BIG elephant in the room is that there are effective, cheap, successful treatments for COVID – thereby nullifying the need for a “vaccine”. The reason the EUA for these injections is still in play is due to the censorship and banning of effective treatments, and the horrific conflicts of interest in public health.

Chronic UTIs and Interstitial Cystitis

Why You Should Listen

In this episode, you will learn about chronic UTIs and Interstitial Cystitis.

Watch The Show

Listen To The Show

About My Guest

My guest for this episode is Ruth Kriz. Utilizing her functional medicine background as well as experience in microbiology and teaching pharmacology, Ruth Kriz, MSN, APRN has spent the majority of her professional career as a Nurse Practitioner working with Chronic UTI and Interstitial Cystitis patients. Her practice expanded to patients from almost all the states in the US as well as from 35 countries who came to her seeking answers beyond symptom management. Through molecular testing, an understanding of the genetics common to these patients, and an understanding of how this contributes to chronic infection and biofilms, she has been able to successfully treat this population. These factors have broad implications for other chronic infections (sinus, prostate, ear infections, wounds, etc.) as well as fibromyalgia, cardiovascular disease, and other conditions in which biofilms are an important contributor. She has closed her medical practice, but she has reinvented as a consultant to help practitioners learn how to utilize her approach for curing these patients.

Key Takeaways

  • How do chronic UTIs evolve into Interstitial Cystitis (IC) over time?
  • What are the primary contributors to chronic UTIs and IC?
  • How is the potential for infection best explored in these conditions?
  • What types of microbes are commonly found in these patients?
  • Do chronic Lyme disease and mold illness play a role in these conditions?
  • What are the key genetic contributors?
  • What role does ammonia play in creating the right environment for microbial overgrowth?
  • How might Nrf2 support be helpful in treating these conditions?
  • What is the role of hypercoagulation and biofilm?
  • How does vitamin D impact these conditions?
  • Is MCAS involved in chronic UTIs and IC?
  • Are oxalates a primary contributor?
  • What are some of the treatment options to explore?
  • Why is detoxification support important?
  • What is the prognosis for those dealing with chronic UTIs and IC?

Connect With My Guest

See link for transcript

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