Archive for the ‘Mast Cell Activation Syndrome (MCAS)’ Category

Chronic UTIs and Interstitial Cystitis

Why You Should Listen

In this episode, you will learn about chronic UTIs and Interstitial Cystitis.

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About My Guest

My guest for this episode is Ruth Kriz. Utilizing her functional medicine background as well as experience in microbiology and teaching pharmacology, Ruth Kriz, MSN, APRN has spent the majority of her professional career as a Nurse Practitioner working with Chronic UTI and Interstitial Cystitis patients. Her practice expanded to patients from almost all the states in the US as well as from 35 countries who came to her seeking answers beyond symptom management. Through molecular testing, an understanding of the genetics common to these patients, and an understanding of how this contributes to chronic infection and biofilms, she has been able to successfully treat this population. These factors have broad implications for other chronic infections (sinus, prostate, ear infections, wounds, etc.) as well as fibromyalgia, cardiovascular disease, and other conditions in which biofilms are an important contributor. She has closed her medical practice, but she has reinvented as a consultant to help practitioners learn how to utilize her approach for curing these patients.

Key Takeaways

  • How do chronic UTIs evolve into Interstitial Cystitis (IC) over time?
  • What are the primary contributors to chronic UTIs and IC?
  • How is the potential for infection best explored in these conditions?
  • What types of microbes are commonly found in these patients?
  • Do chronic Lyme disease and mold illness play a role in these conditions?
  • What are the key genetic contributors?
  • What role does ammonia play in creating the right environment for microbial overgrowth?
  • How might Nrf2 support be helpful in treating these conditions?
  • What is the role of hypercoagulation and biofilm?
  • How does vitamin D impact these conditions?
  • Is MCAS involved in chronic UTIs and IC?
  • Are oxalates a primary contributor?
  • What are some of the treatment options to explore?
  • Why is detoxification support important?
  • What is the prognosis for those dealing with chronic UTIs and IC?

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See link for transcript

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MCAS – The Better Approach to Healing Chronic Illnesses


Mast Cell Activation Syndrome – The Better Approach To Healing Chronic Illnesses | Dr. Eric Gordon

Dec 3, 2021
Dr. Eric Gordon joins us to chat about COVID, Lyme Disease, Chronic Fatigue Syndrome, and Mast Cell Activation Syndrome.
  • 00:00Intro
  • 01:48 – Dr. Gordon’s journey in medicine
  • 04:17 – What is keeping you ill
  • 10:53 – Public Health vs. Medicine
  • 15:30 – Rebalancing the immune system
  • 21:48 – All about Mast Cell Activation Syndrome
  • 28:01 – Chronic Fatigue Syndrome
  • 32:32What your body is telling you
  • 35:27 – How stress makes you sick but also gets you well
Additional Resources 👉 Connect with Dr. Eric Gordon here: ———
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Dr. Afrin recently related the story of a patient,

“who in the first year of his life had been perfectly normal and then, within hours of his first DTP vaccine at age one, developed into just a terrible multi-system inflammatory mess, including essentially acute onset autism.” When he was 20 years old, biopsies tested positive for mast cells. He was subsequently treated for MCAS with remarkable improvement.73

Most babies in the U.S. are being given 25 doses of nine different vaccines (or more) by their first birthday and can receive eight or more vaccines simultaneously.74 As mentioned previously, there are ingredients in vaccines that provoke inflammatory responses in the body that involve mast cell activation.75

Although for the past several decades, most pediatricians and public health officials have rejected the possibility of a relationship between vaccination and the development of allergic and autoimmune disorders,76 the apparent increase in mast cell dysregulation in highly vaccinated populations deserves more in-depth investigation.

Mold As a Root Cause of MCAS  Go here for entire article, video, and audio

Why You Should Listen

In this episode, you will learn about mold and mycotoxins as a root cause of Mast Cell Activation Syndrome.

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About My Guest

My guest for this episode is Beth O’Hara.  Beth O’Hara, FN is a Functional Naturopath specializing in complex chronic immune conditions related to Mast Cell Activation Syndrome and Histamine Intolerance.  She is the founder and owner of Mast Cell 360, a Functional Naturopathy Practice designed to look at all factors surrounding health conditions: genetic, epigenetic, biochemical, physiological, environmental, and emotional.  Her subspecialties are Mold Toxicity and Genetic Analysis in the area of Mast Cell Activation and Histamine Intolerance.  She designed Mast Cell 360 to be the kind of practice she wished had existed when she was severely ill with Mast Cell Activation Syndrome, Histamine Intolerance, Neural Inflammation, Lyme, Mold Toxicity, Fibromyalgia, and Chronic Fatigue.  Her mission today is to be a guiding light for others with Mast Cell Activation Syndrome, Histamine Intolerance and these related conditions in their healing journeys.  Through her Mast Cell 360 Root Cause process, she discovers the unique root factors affecting each of her clients’ health issues, building personalized, effective roadmaps for healing.  She holds a doctorate in Functional Naturopathy, a Master’s degree in Marriage and Family Therapy, and a Bachelor’s degree in Physiological Psychology.  She is certified in Functional Genomic Analysis and is a Research Adviser for the Nutrigenetic Research Institute.

Key Takeaways

  • How common is mold as a trigger for MCAS?
  • What internal and external testing options are helpful for exploring mold?
  • What environments are common contributors to mold exposure?
  • What factors have created the perfect storm for mold toxicity?
  • Are some conditions difficult to fix or resistant to treatment if mold has not been addressed first?
  • What is the connection between mold illness and salicylate intolerance?
  • What role do chemicals and pesticides play in terms of toxicant contribution to chronic illness?
  • Does finding Actinomycetes in a water-damaged building change the course of treatment?
  • Are most clients stuck in a Cell Danger Response?
  • What are some seemingly good interventions that may backfire when one is stuck in CDR?
  • What is Beth’s 8 step approach to addressing mold illness?
  • How important is a focus on the nervous system, vagus nerve, and limbic system in support of recovery?
  • Can most clients remediate, or do they need to move?
  • How important is a low lectin diet?
  • What are some tips for improving hydration and constipation?
  • What are some of her favorite tools for stabilizing mast cells?
  • Which binders have been most helpful for her clients?
  • How are detoxification and drainage supported?
  • What tools may be helpful for addition colonization?
  • What does recovery look like?

Connect With My Guest

Related Resources

MC360 Precision Mold Master Class Course
10% off with code BETTERHEALTH

Mast Cell Nervous System Reboot Course
10% off with code BETTERHEALTH

See link for transcript

Lyme Disease: Acute and Chronic-Defined & “It Ain’t Just One Thing”

Samuel M Shor, MD

Objective: Chronic Lyme disease has been a poorly defined term and often dismissed as a fictitious entity. In this paper, the International Lyme and Associated Diseases Society (ILADS) provides its evidence-based definition of chronic Lyme disease.

Definition: ILADS defines chronic Lyme disease (CLD) as a multisystem illness with a wide range of symptoms and/or signs that are either continuously or intermittently present for a minimum of six months. The illness is the result of an active and ongoing infection by any of several pathogenic members of the Borrelia burgdorferi sensu lato complex (Bbsl). The infection has variable latency periods and signs and symptoms may wax, wane and migrate. CLD has two subcategories,

  • CLD, untreated (CLD-U)
  • CLD, previously treated (CLD-PT)

The latter requires that CLD manifestations persist or recur following treatment and are present continuously or in a relapsing/remitting pattern for a duration of six months or more.

Methods: Systematic review of over 250 peer reviewed papers in the international literature to characterize the clinical spectrum of CLD-U and CLD-PT.

Conclusion: This evidence-based definition of chronic Lyme disease clarifies the term’s meaning and the literature review validates that chronic and ongoing Bbsl infections can result in chronic disease.

Use of this CLD definition will promote a better understanding of the infection and facilitate future research of this infection.



Words matter.

This, right here, is a main difference between what mainstream medicine ascribes to and what a Lyme literate doctor ascribes to.  The difference is life-changing to say the least.  Those in the former camp will treat patients with the woefully inadequate 21 days of doxycycline while the latter camp realizes this illness can wax, wane, and linger – and this isn’t even taking into account the many coinfections that can also wax, wane, and linger.  

If patients have numerous persisting infections they have more severe cases for a longer duration of time, requiring numerous medications for far longer than the unscientific CDC Lyme guidelines.

For more:

http://  Approx. 42 Min.

Sept. 30, 2020

It Ain’t Just One Thing

David Kaufman, MD; Ilene Ruhoy, MD, PhD

Chronic Lyme Disease (CLD) is a complex chronic illness. Controversy exists regarding whether it represents persistent Lyme infection or a post-infectious, possibly autoimmune syndrome, or a combination of both. This is an important topic as a greater understanding of CLD can help guide treatment options for these patients who suffer sometimes for decades and are often turned away from healthcare providers. Effective treatment has been notoriously difficult. Importantly, patients with CLD generally meet all the criteria for a diagnosis of ME/CFS. Interestingly as discussed below, these same patients very often present with similar signs, symptoms, and diagnoses that are seen in a large majority of ME/CFS patients regardless of any history of CLD.

We will discuss the diagnostic concept of a Septad which includes:

  • Autoimmune disease
  • Mast Cell Activation Syndrome
  • Dysautonomia including small and large fiber neuropathy
  • Dysmotility/Dysbiosis/SIBO
  • hypermobility Ehler Danlos Syndrome (hEDS)
  • Cranial Cervical Instability (CCI)/Tethered Cord (TC)
  • Infection including especially tick borne diseases, viral reactivation, and mycoplasma

The Septad concept provides a guide for both physician and patient regarding both the work up and the treatment plans. The identification of these particular entities can be made with objective data and can assist physicians in implementing management options. This presentation will briefly discuss each of these disorders including symptoms, evaluation, and possible treatment suggestions.

How Lyme and Hidden Infections Sabotage Our Clinical Outcomes

This article, although a year old, has some great insights.

How Lyme and Hidden Infections Sabotage Our Clinical Outcomes

By Jason Bachewich, ND

What if I told you that as a clinician, you were potentially misdiagnosing a large percentage of your autoimmune patients?  What if the arthritis, Alzheimer’s, cancer, or Grave’s disease was actually caused by an infection?   The research is starting to show that perhaps our bodies are not flawed or simply have bad luck but rather sabotaged by chronic and hidden infections.  Our treatment plans would be different, and our outcomes more positive.  This is the beginning of a whole new understanding of chronic disease, and the potential is hugely exciting.

Lyme disease has been gaining a lot of attention in the media lately.   Doctors are becoming more aware of the symptoms, but why just look at Lyme disease?  There are multiple bacterial, viral, and other parasitic infections that can sabotage our clinical outcomes and have been ignored or assumed to be benign. This article is going to help you to identify those key symptoms to look for, how to test for the infections, and familiarize you with the most common hidden infections that we are not taught about in medical school. (See link for article)



Time for the one germ one drug paradigm to die.  Patients present with complex clinical pictures that can not be explained away simply, but demand astute observation and lengthy medical histories.  It is not uncommon for patients to have multiple things going on simultaneously.

For more:


For the first time, Garg et al. show a 85% probability for multiple infectionsincluding not only tick-borne pathogens but also opportunistic microbes such as EBV and other viruses.

I’m thankful they included Bartonella as that one is often omitted but definitely a player.  I’m also thankful for the mention of viruses as they too are in the mix.  The mention of the persister form must be recognized as well as many out there deny its existence.

Key Quote:  Our findings recognize that microbial infections in patients suffering from TBDs do not follow the one microbe, one disease Germ Theory as 65% of the TBD patients produce immune responses to various microbes.”

Many patients also struggle with mold and mast cell issues:

For more: