Archive for the ‘Bartonella’ Category

10 Top Causes of Symptoms in Chronic Lyme Disease

https://www.prohealth.com/library/ten-common-causes-of-symptoms-in-chronic-lyme-disease-8558

10 Top Causes Of Symptoms In Chronic Lyme Disease

(Please see link above for full article.  Excerpts below)

1) Mold toxicity

Real Time labs is among the most accurate of labs for mold testing. Effective mold toxin binders include the medication cholestyramine and activated charcoal.

2) Parasitic Infections

Parasitic infections are often not detectable on conventional lab tests, and may not even show up in sophisticated stool tests; therefore, using multiple forms of testing to detect parasites, such as electrodermal screening tools such as the Zyto or muscle testing, is important, along with lab testing with reputable labs such as Doctors’ Data.

3) Hormone and Neurotransmitter Imbalances

Replenishing the body’s stores of these chemicals can therefore profoundly support the healing process and Lyme doctors will commonly prescribe bio-identical hormones such as pregnenolone, DHEA and thyroid hormone to their patients, along with amino acids such as L-tyrosine, GABA and 5-HTP, which the body uses to make neurotransmitters. To make these amino acids work in the body, supplemental co-factors such as P5P, SAMe, and methyl B-12 are also sometimes important.

4) Vitamin and Mineral Deficiencies

Common deficiencies include magnesium, Vitamins D, C and B-vitamins; zinc and iron—among others. Supplementation with these nutrients can help to support the body during healing. (For more information on common nutritional deficiencies in Lyme disease and supplements that support the body, I encourage you to check out my 2012 book Beyond Lyme Disease).

5) Inflammation

Reducing inflammation involves mitigating all of its causes, such as removing pathogens and toxins from the body, and downregulating the immune response with nutrients and tools such as low-dose immunotherapy. High-quality, natural anti-inflammatory substances such as curcumin may also be helpful for supporting the body’s inflammatory response.

6) Mitochondrial Dysfunction

Supporting the mitochondria with supplements such as L-carnitine and CO Q-10 can help to mitigate fatigue and other symptoms related to mitochondrial dysfunction.

7) Emotional Trauma

Many studies have proven that trauma suppresses immune function and when prolonged, can open the door to chronic health challenges.

8) A Poor Diet

Removing allergenic foods and consuming fresh, organic “real” food, such as non-GMO, antibiotic, pesticide, and hormone-free meats, poultry, eggs, and other proteins; non-starchy veggies and low-glycemic fruits, along with healthy fats such as olive and coconut oil, can help to alleviate symptoms caused by food.

9) Poor Gastrointestinal Function

Supplementing with GI nutrients such as hydrochloric acid, digestive enzymes and probiotics may help to support gastrointestinal function in those with Lyme.

10) Environmental Toxicity

Sauna therapy, rebounding, coffee enemas, liver cleanses, and taking toxin binders such as zeolite, chlorella, EDTA, activated charcoal—among others, are just a few ways to remove toxins from the body.  Ideally, you’ll want to work with a practitioner who can test your body for toxins and prescribe a regimen in conjunction with Lyme disease treatment based on your needs. The same holds for the other causes of symptoms described here.

This article was first published on ProHealth.com on April 26, 2016 and was updated on September 22, 2020.


Connie Strasheim is the author of multiple wellness books, including three on Lyme disease. She is also a medical copywriter, editor and healing prayer minister. Her passion is to help people with complex chronic illnesses find freedom from disease and soul-spirit sickness using whole body medicine and prayer, and she collaborates with some of the world’s best integrative doctors to do this. In addition to Lyme disease, Connie’s books focus on cancer, nutrition, detoxification and spiritual healing. You can learn more about her work at: ConnieStrasheim.

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**Comment**

Not mentioned is Lyme itself, and the many other potential players.  While parasites apart from Lyme is mentioned, dealing with the infections is paramount.  Of course these infections are indirectly affected by the things listed in the helpful article, but never underestimate the infection(s) themselves.  Good, effective, savvy treatment is required.

For more:

Could You Be Co-infected With Bartonella?

https://globallymealliance.org/could-you-be-co-infected-with-bartonella/

by Jennifer Crystal

I was bitten by a tick in summer 1997 while working at a camp in the woods of Maine. It would be another eight years, however, until I figured out that the rash I developed that summer was a result of a tick bite, and that my subsequent hypoglycemia, crushing fatigue, joint and muscle aches, and fever were caused by the tick-borne diseases Lyme, babesiosis, and ehrlichiosis. That fall of 1997, during my sophomore year of college, I fell ill with the aforementioned symptoms. I missed class. I couldn’t exercise. I could hardly walk to the dining hall.

Because of frequent low blood sugar reactions, I gained a lot of weight very quickly. I felt ashamed of my sudden, noticeable size change. Though I frequently sought care for my flu-like symptoms—often being told I was just run down or stressed—I did not consider that the weight gain might be related to my other symptoms. Medical practitioners didn’t, either; some just told me to go on a diet.

Part of my shame was about deep reddish-purple marks that developed on my chest and in my groin. I assumed these were stretch marks from my skin expanding to accommodate my weight.

Had I shown them to a Lyme Literate Medical Doctor (LLMD), they might have said that instead of stretch marks, lines on my skin possibly could have been striae caused by Bartonella henselae.

As noted on the GLA website, bartonellosis is a bacterial disease starting with a red mark that can become swollen and discolored or even look like “stretchmarks” or striations. Symptoms include swollen lymph nodes (especially under ears), often with conjunctivitis, heart or spleen problems, bone lesions, hepatitis, other eye problems and encephalitis (causing seizures and coma). There is indirect clinical evidence that this is a group of “Bartonella-like organisms” that can co-infect a Lyme patient. Identification of these organisms awaits further scientific study.

Many people with Bartonella henselae also experience pain in the soles of their feet. According to the National Institutes of Health, “This is associated with trauma to blood vessels in the soles of the feet with walking.” Furthermore, “Anemia can occur from Bartonella scavenging nutrients from red blood cells.”

At the time I developed striae, I was also experiencing pain on the soles of my feet when I ran (which I did when I was feeling up to it, as my symptoms waxed and waned). I thought the pain was from heel spurs, or simply because I needed new sneakers.

How easily we explain away symptoms, not realizing they could be related to actual illness.

Though my initial blood test for Bartonella henselae was negative, my LLMD always suspected I might have had it, because of the symptoms I described. The antibiotics he prescribed treated Lyme, ehrlichiosis, and bartonellosis, so our bases were covered regardless. I have not experienced striae or heel pain in years.

Not all patients know about bartonella, and not all doctors, even LLMDs, think to test for it. This oversight could be detrimental to patients, as they might not be receiving the right treatment, or enough of it. If you have other tick-borne illnesses and have not been tested for bartonella, it’s a good idea to ask your LLMD about it. If you have any of the symptoms I’ve described, consider whether bartonella could be the cause.

To read more blogs click here.


jennifer crystal_2

Opinions expressed by contributors are their own.

Jennifer Crystal is a writer and educator in Boston. Her memoir about her medical journey is on submission. Contact her at lymewarriorjennifercrystal@gmail.com.

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**Comment**

This article brings up some great points and reminds me of things I’ve forgotten in our own journey.

The hypoglycemia mentioned can be severe. My husband required food be immediately available. It seemed his body was on hyperdrive and he couldn’t consume enough calories. We had nuts and nut bars stashed everywhere – especially in the car because frightening hypoglycemic episodes would happen while he was driving, making him shake and feel like passing out. (I will add checking your thyroid is a good idea as most patients are typically deficient in thyroid hormones)

The pain in the feet can be severe as well and feel as if someone beat you with a mallet. We also noticed pain in the ankles and wrists – so bad you could drop whatever you were holding due to severe, stabbing pain that felt like a nerve impingement. Going down the stairs and walking is risky because the ankles feel like caving

Bartonella, although not mentioned here, can cause some pretty frightening psychological issues as well. My husband suffered with anxiety would come on like the wind leaving him visibly shaking – afraid for no logical reason. Used to meeting and speaking in front of hundreds of people he would have to periodically cancel meetings as his body rebelled against all logic and common sense. There’s no talking a person out of this. It just is. I had heart involvement that would wake me in the middle of the night with a heart flopping in my chest like a fish flops on the dock after you pull it out of the water. I would lay there and ponder why I was awake and feeling the way I did. This pondering, going through the triage of symptoms can cause an anxiety of its own – as your body seemingly is not communicating with your brain and has gone rogue.

Mainstream doctors haven’t a clue. If I had a dollar for every patient who told me a doctor said their symptoms were due to “anxiety or stress” I’d be a millionaire. These wild, rogue symptoms cause anxiety because they are so unbelievably frightening, but they are the problem and they need to be addressed.

This lack of bodily control is maddening and can be one of the most frustrating aspects of this illness. You become afraid to go anywhere or do anything as your body has a mind of its own. A prisoner in your own home.

For more: https://madisonarealymesupportgroup.com/category/bartonella-treatment/ In my experience, Bartonella is one of the most tenacious coinfections, yet it is completely ignored by mainstream medicine.

Bartonella is also very common in pets and many other bugs, including spiders and mites. Veterinarians are particularly at risk.

What Are Lyme Disease Co-Infections?

https://danielcameronmd.com/lyme-disease-co-infections/

WHAT ARE LYME DISEASE CO-INFECTIONS?

lyme disease co-infections

When Lyme disease was first discovered in 1975, it was the only known tick-borne illness recognized by clinicians. The disease, which is caused by an infection with the bacterium Borrelia burgdorferi, is transmitted through the bite of a black-legged (I. scapularis) tick.

Today, ticks harbor multiple infectious pathogens that can be transmitted to humans through a tick bite or tainted blood transfusion. The Centers for Disease Control and Prevention (CDC) now reports that “a single tick can transmit multiple pathogens, including bacteria, viruses, and parasites.” [1] This can result in patients developing what is referred to as Lyme disease “co-infections.”

In fact, between 2004 and 2016, the CDC identified 7 new tick-borne microbes capable of infecting humans. [1]

While most Lyme disease co-infections are acquired through the bite of an infected tick, several can be transmitted through contaminated blood transfusions. One investigation concluded, “Aside from a Babesia infection, Anaplasma is the most frequent transfusion-transmitted [tick-borne agent] with rapidly increasing clinical cases.” [2]

Ticks harbor multiple pathogens

According to a study in Suffolk County, Long Island, more than half (67%) of the ticks collected were harboring at least one pathogen. The causative agent of Lyme disease, Borrelia burgdorferi was the most prevalent (57% in adults; 27% in nymphs), followed by Babesia microti (14% in adults; 15% in nymphs).

Another study indicates that “co-infection occurs in up to 28% of black-legged ticks” in Lyme endemic areas of the United States.

Furthermore, researchers found that among infected ticks collected, 45% were co-infected and carried up to 5 different pathogens. The most prevalent co-infections included Bartonella henselae (17.6%) and Rickettsia of the spotted fever group (16.8%).

Lyme disease with co-infections

Researchers from Columbia University, Tufts Medical Center, and Yale School of Medicine examined the extent of co-infections in patients diagnosed with Lyme disease. Their findings are alarming.

  • 40% of Lyme disease patients had concurrent Babesia
  • 1 in 3 patients with Babesia had concurrent Anaplasmosis
  • Two-thirds of patients with Babesiosis experienced concurrent Lyme disease and one-third experienced concurrent Anaplasmosis

Recognizing and treating co-infections

As tick populations explode and expand into new geographic regions and cases of Lyme disease continue to soar, there is growing and warranted concern surrounding the medical communities’ ability to recognize, diagnose, and treat Lyme disease co-infections.

Sanchez-Vicente points out that nearly 1 in 4 black-legged ticks tested in their study had multiple infections. This finding “justifies the modification of the clinical approach to tick-borne diseases to cover all infection possibilities.”

Unfortunately, testing for co-infections rarely occurs. One study found that out of nearly 3 million specimens, only 17% were tested for non-Lyme tick-borne diseases.

Yet, an accurate diagnosis is critical, given that patients may require different treatment depending upon the type of co-infection. For instance, antibiotics prescribed for Lyme disease may be ineffective in treating parasitic or viral tick-borne diseases such as Babesia.

Most common co-infections

Lyme disease is the most common tick-borne illness in the United States. But it’s no longer the only threat. Lyme disease co-infections are becoming the norm, not the exception. The most frequently diagnosed tick-borne co-infections include Babesia, Anaplasmosis, Ehrlichia, Bartonella, Southern Tick-Associated Rash Illness (STARI), and Borrelia miyamotoi.

BABESIA

Babesia is a parasite that infects red blood cells. This parasitic infection is usually transmitted by a tick bite but can be acquired through a contaminated blood transfusion. There have also been reports of congenital transmission of Babesiosis, although rare.

Saetre describes two cases of infants with congenital babesiosis born to mothers with prepartum Lyme disease and subclinical Babesia microti infection. [3] Additionally, congenital transmission has been described in 7 previous cases, in which the infants presented with fever, anemia, and thrombocytopenia. [3]

Read more: Transfusion-transmitted Babesiosis popping up in more states in USA

Most cases of Babesia involve the strains: Babesia microti and Babesia duncani.

Symptoms typically include irregular fevers, chills, sweats, lethargy, headaches, nausea, body aches, fatigue, and in some cases, shortness of breath. But manifestations can vary.

A case series published in the Nurse Practitioner Journal demonstrates the difficulty in diagnosing the disease, as it can cause a wide range of clinical presentations.

Babesia and Lyme disease

Babesia is often present with Lyme disease and can increase the severity of Lyme disease. One study found patients co-infected with Lyme disease and Babesia experienced fatigue, headache, sweats, chills, anorexia, emotional lability, nausea, conjunctivitis, and splenomegaly more frequently than those with Lyme disease alone.

Listen to PODCAST: Delayed onset of Babesia in a Lyme disease patient

Babesia can also increase the duration of illness with Lyme disease. One study found that 50% of co-infected patients were symptomatic for 3 months or longer, compared to only 4% of patients who had Lyme disease alone.

Testing and treatment

Babesia can also be difficult to diagnose with current testing. The parasite was detected microscopically in as few as one-third of patients with Babesia. Specific amplifiable DNA and IgM antibody were more likely to be positive.

The reliability of tests for Babesia in actual practice remains to be determined.

Babesia is treated with a combination of anti-malaria medications and antibiotics such as Atovaquone with azithromycin.

EHRLICHIA

Ehrlichia is a tick-borne bacteria that infects white blood cells, but it has been found in spleen, lymph node, and kidney tissue samples. An infection with Ehrlichia can lead to Ehrlichiosis.

The infection is caused by Ehrlichia chaffeensis and Ehrlichia chagrins. The bacteria is transmitted by the Lone Star tick (Amblyomma americanum) and the black-legged tick (Ixodes scapularis).

Ehrlichia is typically transmitted by a tick bite. Only rarely, has the infection been associated with blood transfusion or organ transplant cases. According to the CDC, there have been two confirmed instances of infection occurring after kidney transplants from a common donor.

Symptoms and Treatment

Symptoms may include fatigue, fevers, headaches, and muscle aches. It can be treated with antibiotics doxycycline, minocycline, and Rifampin.

If left untreated, the disease can become severe and require hospitalization.

ANAPLASMOSIS

Anaplasmosis was previously known as Human Granulocytic Ehrlichiosis or HGE. The disease can be difficult to distinguish from Ehrlichiosis, Lyme disease, and other tick-borne illnesses.

This emerging infectious disease remains under-recognized in many areas of the United States. [4] It is caused by the bacteria Anaplasma phagocytophilum.

Anaplasmosis is spread by tick bites from the black-legged tick and western black-legged tick. Although it is reportedly rare, anaplasmosis has been transmitted through contaminated blood transfusions.

In fact, Mohan and Leiby contend that aside from a Babesia infection, “Anaplasma is the most frequent transfusion-transmitted [tick-borne agent] with rapidly increasing clinical cases.” [2]

In general, most infections with anaplasmosis are mild, “however, up to 36% of patients require hospitalization, with 3% of those having life-threatening complications.” [5]

Symptoms may include headaches, fevers, chills, malaise, and muscle aches. There have been a few reported cases describing pulmonary complications, as well. In fact, one study recommends that “anaplasmosis be included in the differential diagnosis for atypical respiratory presentations.” [5]

And although uncommon, there have been patients with anaplasmosis who did not exhibit any symptoms (asymptomatic). “It is, therefore, crucial for clinicians to be aware of potential asymptomatic anaplasmosis following a tick bite,” writes Yoo and colleagues. [6]

Anaplasmosis can be treated with antibiotics such as doxycycline, minocycline, and Rifampin.

BARTONELLA

Various Bartonella species have been found in black-legged ticks in northern New Jersey and in western black-legged ticks in California.

Bartonella can be contracted through a cat scratch or bite, causing “cat scratch fever.” But it can also be transmitted by a tick bite. In fact, “ticks and small rodents are known hosts of Bartonella and play a significant role in the preservation and circulation of Bartonella in nature.” [7]

Psychiatric presentations and other symptoms

Some patients exhibit a streak-mark rash that resembles stretch marks. Symptoms may include fever, headaches, fatigue, and swollen glands.

Several studies indicate an association between Bartonella and psychiatric symptoms. Investigators describe case studies of patients with new-onset psychiatric symptoms such as sudden agitation, panic attacks, and treatment-resistant depression possibly due to Bartonella.

Another case study highlights a young boy with a Bartonella infection who developed neuropsychiatric symptoms and was later diagnosed with pediatric acute-onset neuropsychiatric syndrome (PANS), a type of basal ganglia encephalitis. [8]

Bartonella can be treated with antibiotics such as doxycycline, minocycline, azithromycin, trimethoprim-sulfamethoxazole, clarithromycin, and Rifampin.

SOUTHERN TICK ASSOCIATED RASH ILLNESS (STARI)

STARI is an emerging tick-borne illness related to Lyme disease and was identified in the southeastern and south-central United States.

STARI is believed to be transmitted by the Lone Star tick; however, it is not officially confirmed as of yet.

The hallmark sign of STARI is an EM-like rash similar to that seen in Lyme disease. Symptoms may include fevers, headaches, stiff neck, joint pain, and fatigue.

The long term consequences and treatment of the illness have not been established.

It is not known whether antibiotic treatment is necessary or beneficial. Nevertheless, because STARI resembles early Lyme disease, physicians will often treat patients with oral antibiotics.

BORRELIA MIYAMOTOI

B. miyamotoi is increasingly being recognized as the agent of a nonspecific febrile illness often misdiagnosed as acute Lyme disease without rash, or as ehrlichiosis.” [9]

Borrelia miyamotoi (BMD) is a spiral-shaped bacteria that causes tick-borne relapsing fevers. However, investigators point out, Borrelia miyamotoi “should not be assumed to be biologically similar to the true relapsing fever spirochetes maintained by argasid (“soft”) ticks, nor to cause typical relapsing fever.” [9]

It appears to be a common infection in areas endemic for Lyme disease. [9]

Symptoms and prevalence

A 2011 study found the disease to generally present with more systemic signs and symptoms, particularly headache and fever, compared to Lyme disease. [10]

“Virtually all patients presented with fever … fatigue, and headache …. The next most common signs and symptoms were myalgia, chills, nausea and arthralgia, characterizing 30%–60% of the patients.” [10]

Other investigators report that “patients infected with B. miyamotoi in the United States typically do not have a rash.” But they may present with “a fever in conjunction with headache (96%), myalgia (84%), arthralgia (76%), and malaise/fatigue (82%).”

READ MORE: Tiny larval ticks can transmit Borrelia miyamotoi

The prevalence of the disease is unknown but investigators report that  “studies in New England suggest that Borrelia miyamotoi infection may be as common as anaplasmosis and babesiosis.

They also point out:

  • “Human cases are likely to be found wherever Lyme disease is endemic.”
  • “B. miyamotoi may cause serious complications, including meningoencephalitis in immunocompromised hosts.”
  • “Several studies suggest that B. miyamotoi may be transmitted through blood transfusion, consistent with the high levels of spirochetemia that occur with Borrelia species that cause relapsing fever.”

Borrelia miyamotoi is particularly concerning given that the bacterium can be transmitted to a person within the first 24 hours of tick attachment. And “the probability of transmission increases with every day an infected tick is allowed to remain attached.”

Diagnostic testing is limited. Although the CDC recommends using PCR and antibody-based tests to confirm a diagnose of B. miyamotoi, a recent study finds blood smears have poor sensitivity for confirming the disease. [9] And there is no FDA approved diagnostic test for the disease.

Treatment thus far is similar to that of Lyme disease. Studies show that doxycycline and amoxicillin have effectively treated B. miyamotoi infection in patients.

Remember, tick-borne co-infections are the norm, not the exception.

Editor’s Note: Practitioners should consider co-infections in the diagnosis when a patient’s symptoms are severe, persistent, and resistant to antibiotic therapy. Physicians have found that co-infections typically exacerbate Lyme disease symptoms.

References:
  1. CDC Vital Signs, Weekly / May 4, 2018 / 67(17);496–501. https://www.cdc.gov/mmwr/volumes/67/wr/mm6717e1.htm
  2. Mohan KVK, Leiby DA. Emerging tick-borne diseases and blood safety: summary of a public workshop. Transfusion. 2020 Jul;60(7):1624-1632. doi: 10.1111/trf.15752. Epub 2020 Mar 24. PMID: 32208532.
  3. Kirsten Saetre, Neetu Godhwani, Mazen Maria, Darshan Patel, Guiqing Wang, Karl I Li, Gary P Wormser, Sheila M Nolan, Congenital Babesiosis After Maternal Infection With Borrelia burgdorferi and Babesia microti, Journal of the Pediatric Infectious Diseases Society, Volume 7, Issue 1, March 2018, Pages e1–e5, https://doi.org/10.1093/jpids/pix074
  4. Rocco JM, Mallarino-Haeger C, McCurry D, Shah N. Severe anaplasmosis represents a treatable cause of secondary hemophagocytic lymphohistiocytosis: Two cases and review of literature. Ticks Tick Borne Dis. 2020 Sep;11(5):101468. doi: 10.1016/j.ttbdis.2020.101468. Epub 2020 May 23. PMID: 32723647.
  5. Jose E Rivera, Katelyn Young, Tae Sung Kwon, Paula A McKenzie, Michelle A Grant, Darrell A McBride, Anaplasmosis Presenting With Respiratory Symptoms and Pneumonitis, Open Forum Infectious Diseases, Volume 7, Issue 8, August 2020, ofaa265, https://doi.org/10.1093/ofid/ofaa265
  6. Yoo J, Chung JH, Kim CM, Yun NR, Kim DM. Asymptomatic-anaplasmosis confirmation using genetic and serological tests and possible coinfection with spotted fever group Rickettsia: a case report. BMC Infect Dis. 2020;20(1):458. Published 2020 Jun 30. doi:10.1186/s12879-020-05170-9
  7. Hao L, Yuan D, Guo L, et al. Molecular detection of Bartonella in ixodid ticks collected from yaks and plateau pikas (Ochotona curzoniae) in Shiqu County, China. BMC Vet Res. 2020;16(1):235. Published 2020 Jul 9. doi:10.1186/s12917-020-02452-x
  8. Breitschwerdt EB, Greenberg R, Maggi RG, Mozayeni BR, Lewis A, Bradley JM. Bartonella henselae Bloodstream Infection in a Boy With Pediatric Acute-Onset Neuropsychiatric Syndrome. J Cent Nerv Syst Dis. 2019;11:1179573519832014. Published 2019 Mar 18. doi:10.1177/1179573519832014
  9. Telford SR, Goethert HK, Molloy PJ, Berardi V. Blood Smears Have Poor Sensitivity for Confirming Borrelia miyamotoi Disease. J Clin Microbiol. 2019 Feb 27;57(3):e01468-18. doi: 10.1128/JCM.01468-18. PMID: 30626663; PMCID: PMC6425185.
  10. Telford SR, Goethert HK, Molloy PJ, Berardi V. Blood Smears Have Poor Sensitivity for Confirming Borrelia miyamotoi Disease. J Clin Microbiol. 2019 Feb 27;57(3):e01468-18. doi: 10.1128/JCM.01468-18. PMID: 30626663; PMCID: PMC6425185.

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For more:

Stealth Infections & Their Detection

Dr.-Schwarzbach-Stealth-Infections-and-their-Detection (1)  pdf here

iu-105

Armin Schwarzbach PhD

Medical doctor and Specialist for Laboratory Medicine

Augsburg, Germany

AONM Annual Conference London, November 19th 2017

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**Comment**

Excellent presentation on the following stealth pathogens:

  • Mycoplasma
  • Bartonella
  • Babesia
  • Ehrlichia/Anaplasma
  • Chlamydia pneumoniae
  • Yersinia
  • Coxsackie viruses (B1, A7, A16) and many others 
  • Borrelia burgdorferi , in all its forms

While Dr. Schwarzbach wants to blame “ecosystem disruption” for the mess we are in, I think it more likely to be due to laboratory experimentation/manipulation (bioweaponization), dropping ticks from airplanes, and migratory birds and animals transporting ticks far and wide:

https://madisonarealymesupportgroup.com/2020/09/25/why-should-we-care-about-lyme-disease-a-colorful-tale-of-government-conflicts-of-interest-probable-bioweaponization-and-pathogen-complexity/

Prevalence of Bartonella sp. in United States Military Working Dogs With Infectious Endocarditis: A Retrospective Case-Control Study

https://pubmed.ncbi.nlm.nih.gov/31830708/

Prevalence of Bartonella sp. in United States military working dogs with infectious endocarditis: a retrospective case-control study

Abstract

Objectives: Bartonella infection has been associated with endocarditis in humans, dogs, cats and cattle. In order to evaluate the importance of this pathogen as a possible source of endocarditis in United States military working dogs (MWDs), we performed a retrospective case-control study on 26 dogs with histological diagnosis of culture negative endocarditis (n = 18), endomyocarditis (n = 5) or endocardiosis (n = 3) and 28 control dogs without any histological cardiac lesions.

Methods: DNA was extracted from paraffin embedded cardiac valves and tissues from case and control dogs and submitted to PCR testing with primers targeting the Bartonella gltA gene. PCR-RFLP using four restriction endonucleases and partial sequencing was then performed to determine the Bartonella species involved.

Results:

  • Nineteen (73%) cases were PCR positive for Bartonella, including B. henselae (8 dogs), B. vinsonii subsp. berkhoffii (6 dogs), B. washoensis (2 dogs) and B. elizabethae (1 dog).
  • Only one control dog was weakly PCR positive for Bartonella.
  • Based on the type of histological diagnosis, 13 (72.2%) dogs with endocarditis, 3 (60%) dogs with endomyocarditis and all 3 dogs with endocardiosis were Bartonella PCR positive.

Conclusions: Bartonella sp. Infections were correlated with cardiopathies in US military working dogs. Systemic use of insecticides against ectoparasites and regular testing of MWDs for Bartonella infection seem highly appropriate to prevent such life-threatening exposures.

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**Comments**

Dogs are sentinels for human tick-borne diseases and should be a warning shot over the bow. This study clearly shows Bartonella is a huge player in heart issues and should always be considered.  Mainstream medicine continues to falsely believe this is a benign infection that will resolve on its own.  

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