LDN, Endorphins, and the Brain

When it was introduced in the mid-1980s, naltrexone was used for blocking opioid receptors. These receptors are meant to be activated by hormones produced by the body called endorphins and enkephalins. However, opioid drugs also stimulate these receptors.

Large doses of naltrexone were originally used for treating drug addiction by blocking the body’s opioid receptors, and therefore the effects of opioid drugs, completely. In doing so, however, it completely blocked the body’s endorphins and enkephalins as well. This was ultimately harmful to health since these hormones play critical roles in myriad parts of the body, such as the immune system.

In contrast, low doses of naltrexone act by temporarily blocking opioid receptors. This causes the body to increase its production of endorphins and enkephalins. In turn, these hormones work to relieve pain, reduce inflammation, and contribute to well-being while avoiding the adverse health effects associated with larger naltrexone doses.

Studies have shown that low-dose naltrexone (LDN) offers multiple health benefits. It has been used in a wide range of treatments for a variety of conditions, including:

  • Hashimoto’s disease
  • Chronic pain
  • Traumatic brain injury (TBI)
  • Cancer
  • Sjögren’s Syndrome
  • Autism
  • Dry Eye Syndrome

(See link for article)

LDN, Autoimmune Disorders, Cancer, Treating Pain, and More

The late Dr. Bernard Bihari discovered and developed the therapeutic use of low-dose naltrexone (LDN) in the mid-1980s while practicing internal medicine in New York City. He was treating drug addicts with a new drug, Naltrexone, which blocked the heroin “high.” Unfortunately, 50 milligrams daily had unpleasant side effects. When his addicts started dying from AIDS, he began to search for a drug that would help them.

Dr. Bihari knew that endorphins, small neurochemicals produced by the body, had pain-relieving, anti-inflammatory properties. Dr. Bihari and his colleagues hired a lab scientist to measure patient endorphin levels. He discovered that his HIV patients had sub-normal endorphin levels. His team determined that LDN doses ranging from 1.75 to 4.5 milligrams increased endorphin levels by two to three hundred percent. By blocking the body’s endorphin receptors, LDN caused an overproduction of endorphins.

Dr. Bihari then started a small foundation to study the use of LDN in HIV patients. After one year, he discovered that the patients who took LDN had an eight percent death rate while patients taking placebo had a thirty-three percent death rate. He and his colleagues went on to treat hundreds of patients with LDN.

Endorphins have a positive effect on the immune system by increasing T-helper and natural killer cells. Not only does LDN help people with autoimmune diseases like multiple sclerosis (MS), it also seems to be beneficial as an adjunct treatment for certain types of cancer.  (See link for article)

For more articles by Women’s International Pharmacy on LDN:



If you are a Lyme/MSIDS patient and do not know about LDN, please learn about it and talk about it with your doctor.  Many patients have benefitted from LDN which is an inexpensive, compounded drug that helps so many things patients struggle with.  For more:

S1E102 – Slyme – an interview with Jenna Luché-Thayer

Ms. Luché-Thayer is the 59-year-old founder and director of the Ad Hoc Committee for Health Equity in ICD11 Borreliosis Codes

Tick Boot Camp’s guest today is Jenna Luché-Thayer. Ms. Luché-Thayer is the 59-year-old founder and director of the Ad Hoc Committee for Health Equity in ICD11 Borreliosis Codes, and she’s from Florida. She first experienced the symptoms of a tick disease in 1976, when she was just 16 years old. She had a fever, extreme fatigue, joint pain, and Bell’s palsy. Her illness came and went, but it took over 35 years for Ms. Luché-Thayer to receive a Lyme diagnosis. This expert brilliantly details what it is like to be a woman on the Lyme journey. If you would like to learn more about the amazing work that Ms. Luché-Thayer has done to give back to the Lyme community since her diagnosis, then tune in now!

Thayer also recently wrote a very timely article on how we need to drop the term “post treatment Lyme disease” like a bad habit:

Reasons for Lyme Nonprofits to Disown Post Treatment Lyme Disease Syndrome: A Case Study

Jenna Luche-Thayer

Senior Advisor – US Government, United Nations, non-profits, corporate social responsibility programs


The denial of evidence showing persistent Lyme infection is a critical obstacle to adequate treatment. This case study demonstrates how funding Post Treatment Lyme Disease Syndrome (PTLDS) and Post Treatment Lyme Symptoms (PTLS) research may create further impediments to sufficient treatment. PTLDS/PTLS are terminology developed for ‘limited research constructs’. These research terms are frequently misappropriated as clinical diagnoses that wrongly infer underlying infection has been adequately treated —even when the patient has recurring symptoms [1].

Persons suffering from persistent Lyme infection, or any chronic illness, may develop secondary psychosomatic and psychiatric disorders. The misuse of PTLDS/PTLS in clinical settings often results in treatment limited to the secondary psychosomatic and psychiatric disorders and denial of adequate antimicrobials for the underlying infection.

This situation is encouraged by government funders of PTLDS/PTLS studies that tend to concentrate on possible psychosomatic and psychiatric aspects of PTLDS/PTLS and largely ignore infectious causes.

This case study is limited to the PTLDS/PTLS research focus by one influential Lyme patient advocacy organization, namely the Lyme Disease Association, Inc (LDA). This organization was chosen because they have the only patient advocate who is a voting member of the Federal Tick Borne Diseases Working Group. This assessment is based on information taken from the LDA website —53 Publications for LDA-Funded Research— and focuses on the 11 publications that use PTLDS/PTLS terminology. (See tables below for publication details —retrieved July 20, 2020)

(See link for article)


For more:


It only takes ONE viral particle to spread disease.  ONE!

New Health Problems Emerging from Continuous Mask Wearing, but “Attempted Murder” Charges Sought for Those Who Refuse to Wear Masks

Comments by Brian Shilhavy
Editor, Health Impact News

The NY Post published an article recently interviewing dentists who are claiming:

“We’re seeing inflammation in people’s gums that have been healthy forever, and cavities in people who have never had them before,” says Dr. Rob Ramondi, a dentist and co-founder of One Manhattan Dental. “About 50% of our patients are being impacted by this, [so] we decided to name it ‘mask mouth’ — after ‘meth mouth.’ ”

There is so much news on the topic of mandatory masks, that it is hard to keep up with it all. Countries and other large areas that do NOT mandate face masks are actually seeing FEWER new cases of COVID. (See the Liberty Report show video below.)

In Nashville, a Council Member has publicly stated that people who refuse to comply with government edicts to wear masks should be charged with murder or attempted murder. (Source.)

When are people going to wake up to the face mask scam?

Tyrants dictate their use, mainly for motives of profit (see: Booming Face Mask Business in U.S. Creating Instant Millionaires Using Government Funds to Buy Masks from China) or social engineering, and people don’t seem to be intelligent enough to ask basic questions about these mask mandates, such as,

  • if they are actually effective, then what type of mask?
  • How does one dispose of them as bio-hazard waste?
  • How often should one be worn before discarded?, etc.
The evidence is overwhelming now: face masks are harming people and protecting nobody.

Dr. Ron Paul covers these issues, and he has also written a new article about the rapid loss of civil rights as the police state tightens it grip on the public.

Coronavirus is the New ‘Terrorism’

by Dr. Ron Paul
Ron Paul Institute for Peace and Prosperity

House Speaker Nancy Pelosi has proposed the next multi-trillion dollar “coronavirus relief” spending bill that will support testing, tracing, treatment, isolation, and mask policies that have been part of a “national strategic plan” she has been advocating.

The Trump administration is not opposing Pelosi’s plan on principle. Instead, it is haggling over the price.

But, even if the strategic plan could be implemented at little or no monetary cost, it would still impose an unacceptable cost in lost liberty.

Pelosi’s plan will lead to either a federal mask mandate or federal funding of state and local mask mandate enforcement. Those who resist wearing masks could likely be reported to the authorities by government-funded mask monitors.

We can label this the “Stasi” approach to health policy, after the infamous East German secret police force.

Contact tracing could lead to forcing individuals to download a tracing app. The app would record where an individual goes and alert authorities that an individual has been near someone who has tested positive for coronavirus.

The strategic plan could eventually include Bill Gates’ and Anthony Fauci’s suggestion that individuals receive “digital certificates” indicating they are vaccinated for or immune to coronavirus.

A certificate would be required before an individual can go to work, to school, or even to the grocery store.

The need to demonstrate vaccination for or immunity to coronavirus in order to resume normal life would cause many people to “voluntarily” receive a potentially dangerous coronavirus vaccine.

The Trump administration has already spent billions of dollars to support efforts of companies to develop a coronavirus vaccine. Policymakers have stated that once a vaccine is developed it will be rushed into production and onto the market.

Supporters of expediting production and use of a vaccine should remember the 1976 swine flu vaccine debacle. The swine flu vaccine was rushed into production in response to political pressure to “do something.”

The result was a vaccine that was more of a danger than the flu.

Unfortunately, those who raise legitimate concerns regarding the safety of vaccines are smeared as “conspiracy theorists.” This is the equivalent of stating that anyone who dares criticize our interventionist foreign policy “hates freedom” and is probably a “terrorist sympathizer.”

Unique Patient Identifier

The coronavirus panic has given new life to the push for a unique patient identifier. The unique patient identifier was authorized in 1996, but appropriations bills since 1998 have contained a provision forbidding the federal government from developing and implementing the identifier.

Unfortunately, two weeks ago, the House of Representatives voted to repeal the ban. The unique patient identifier would aid government efforts to track and vaccinate every American, as well as to infringe in other ways on liberty in the name of “health.”

Politicians and bureaucrats cannot eliminate a virus any more than they can eliminate terrorism. What they can do is use terrorism, a virus, and other real, exaggerated, or manufactured crises to expand their power at the expense of our liberty.

Politicians will never resist the temptation to use crises as excuses to gain more power. Therefore, it is up to those of us who know the truth to spread the message of liberty and grow the liberty movement.

A strong liberty movement is the only thing that can force the politicians to stop stealing our liberty while promising phantom security from terrorists and viruses.

Read the full article at the Ron Paul Institute for Peace and Prosperity

Murder Charge For Not Wearing A Mask?

_______________________  Video interview here


Translation: You can wash your hands all you want or take a bath in hand sanitizer. Or not. You can wear any mask you want. Or not. It’s not going to matter. It won’t make any difference on whether you get Wuhan flu or not. That’s the science.





Reports of reinfection instead may be cases of drawn-out illness. A decline in antibodies is normal after a few weeks, and people are protected from the coronavirus in other ways.
Megan Kent of Salem, Mass., tested positive for coronavirus in March 30 after feeling sick. She got better, went back to work and then felt sick again in May, testing positive a second time for the virus.
Credit…Kayana Szymczak for The New York Times

The anecdotes are alarming. A woman in Los Angeles seemed to recover from Covid-19, but weeks later took a turn for the worse and tested positive again. A New Jersey doctor claimed several patients healed from one bout only to become reinfected with the coronavirus. And another doctor said a second round of illness was a reality for some people, and was much more severe.

These recent accounts tap into people’s deepest anxieties that they are destined to succumb to Covid-19 over and over, feeling progressively sicker, and will never emerge from this nightmarish pandemic. And these stories fuel fears that we won’t be able to reach herd immunity — the ultimate destination where the virus can no longer find enough victims to pose a deadly threat.

But the anecdotes are just that — stories without evidence of reinfections, according to nearly a dozen experts who study viruses.  (See link for article)



Important quote:

Dr. Mina had choice words for the physicians who caused the panic over reports of reinfections. “This is so bad, people have lost their minds,” he said. “It’s just sensationalist click bait.”

“Here, we review the evidence base on the effectiveness of nonpharmaceutical personal protective measures and environmental hygiene measures in non-healthcare settings and discuss their potential inclusion in pandemic plans. Although mechanistic studies [*] support the potential effect of hand hygiene or face masks, evidence from 14 randomized controlled trials of these measures did not support a substantial effect on transmission of laboratory-confirmed influenza. We similarly found limited evidence on the effectiveness of improved hygiene and environmental cleaning.”

For more:

Telling quote:

“The entire world simply claimed that there was no immunity…..that wasn’t science, but pure speculation based on a gut feeling that was then parroted by everyone.” Beda Stadler


The virus is gone now but he states will probably come back in winter but it will NOT be a second wave – just a cold.  He states the young walking around with face-masks on would be better off wearing a helmet because the risk of something falling on their head is greater than getting a serious case of COVID-19.According to John P A Ioannidis’s work, those below the age of 65 make up only .6 to 2.6% of all fatal COVID cases.

Important quote:

Scientists are getting away scot-free for causing billions of dollars’ worth of damage and this is something that cannot be allowed to happen. It’s not just the World Health Organisation. Ferguson wanted Sweden to lockdown, got Britain to lockdown, and when the numbers become normal, exactly what you would expect without lockdown. He then says, ah it’s because of lockdown. This is terrible science. This is science which should go on trial.. – Stanford biophysicist and Nobel Laureate Michael Levitt

Levitt states Sweden is the only country who did the right thing and that herd immunity occurs at 15% NOT 80%. He also states that these epidemiologists stirred up the same panic with Ebola and Bird Flu, but didn’t shut down society.  He states our mistake was listening to them.  He states that the level of stupidity has been amazing…..and that it’s exactly as dangerous as the flu.


Beth Goodman and Patricia Whitley-Williams

This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.

  1. Beth Goodman, MD*
  2. Patricia Whitley-Williams, MD
  1. *Department of Pediatrics, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ
  2. Department of Pediatrics and Division of Allergy, Immunology, and Infectious Disease, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ

    Drs Goodman and Whitley-Williams have disclosed no financial relationships relevant to this article. This commentary does not contain a discussion of an unapproved/investigative use of a commercial product/device.

Pediatricians are often familiar with cat-scratch disease (CSD), but many are not familiar with the other manifestations of Bartonella infection. The Bartonella genus of bacteria are fastidious and slow-growing gram-negative bacilli. From 1889 to the present, 8 different Bartonella species have been identified, with differing manifestations. This In Brief reviews the illnesses caused by 3 of the more common Bartonella strains: henselae, quintana, and bacilliformis.

CSD, caused by Bartonella henselae, is the most common Bartonella infection, but it is also a “newer” manifestation. CSD was first reported clinically in 1950, yet B henselae was not identified as the etiologic agent until 1983.

In immunocompetent patients, typical (uncomplicated) CSD is characterized by regional lymphadenopathy, the most common manifestation of B henselae infection, along with a history of cat exposure. For most patients with CSD, regional lymphadenopathy is the only symptom. In approximately 30% of patients with CSD, mild systemic symptoms are also present, including low-grade fever, fatigue, and headache. A skin papule, vesicle, or pustule may be present at the presumed site of inoculation, which is often a bite or scratch from an infected cat. Regional lymphadenopathy develops approximately 1 to 2 weeks after the inoculation. The affected nodes are most frequently in the axillary, cervical, and inguinal areas, and the skin overlying the affected lymph nodes is often tender, warm, erythematous, and indurated, consistent with a bacterial lymphadenitis. Approximately 10% of affected nodes suppurate spontaneously.

Atypical (complicated) CSD is a disseminated infection that develops in 5% to 14% of immunocompetent patients and may involve almost any organ system. Ocular manifestations of B henselae occur in 5% to 10% …

(See link for article you can purchase)



Due to the increasing prevalence of Bartonella, I hope doctors are utilizing articles like this one and learning what to look for.

Here’s 18 pediatric cases of Bartonella in a singular Hawaiian facility:  University of Hawaii study shows Hawaii keiki are more than three times more likely to get severe forms of cat scratch disease than mainland kids.

This adolescent had sudden onset schizophrenia caused by Bartonella:

For more: