Archive for the ‘Tularemia’ Category

Serendipitous Treatment of Tularemia in Pregnancy

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804751/

Serendipitous Treatment of Tularemia in Pregnancy

Published online 2019 Sep 24. doi: 10.1093/ofid/ofz413

Abstract

We present a young pregnant woman who developed ulceroglandular tularaemia following a bite wound from a kitten. She grew Francisella tularensis from the ulcer. While awaiting bacterial culture results and serology for Bartonella, she was treated with azithromycin, with resolution of fever and axillary tenderness. Treatment recommendations for tularemia are either gentamicin or doxycycline, both of which can be perilous to the fetus. A Centers for Disease Control and Prevention report on the macrolide susceptibility of North American isolates of this organism has been underappreciated. The unanticipated result from this patient may give another potential option for treatment of tularemia in pregnancy.

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Please know ticks transmit Tularemia:  https://madisonarealymesupportgroup.com/2019/02/18/tularemia-in-minnesotan-ticks/

https://madisonarealymesupportgroup.com/2016/10/25/of-rabbits-and-men/

It also kills: https://madisonarealymesupportgroup.com/2018/09/28/after-tularemia-death-experts-stress-education/

Now, Dr. Brown said an increasing number of cases of tularemia that were transmitted by a tick bite are being seen. Tularemia is transmitted by dog ticks, which also can transmit Rocky Mountain spotted fever. Lyme disease, babesiosis and erlichiosis, which are transmitted by tiny deer ticks, also occur on the Vineyard.

And with the relatively recent spread on the Island of lone star ticks, a new species, Dr. Brown said there is added concern about the potential for more disease transmission.

Sweden Reports Surge in Tularemia Cases

http://outbreaknewstoday.com/sweden-reports-surge-in-tularemia-cases-29406/

Sweden reports surge in tularemia cases

August 12, 2019

By NewsDesk  @infectiousdiseasenews

The number of reported cases of human tularemia has increased significantly in Sweden during the end of July and the beginning of August, according to the Public Health Agency of Sweden, or Folkhälsomyndigheten (computer translated).

Image/Folkhälsomyndigheten

A total of 212 confirmed cases have been reported, significantly more than reported during an average year, officials note.

Most cases of illness have been reported from Dalarna, Gävleborg and Örebro counties, but the last week also saw an increase in the counties of Västerbotten and Norrbotten. Since the number of illness cases is usually highest in September, the outbreak is expected to grow further in the coming weeks.

The animals most likely to carry the disease are wild hares, hence the name rabbit fever, aka tularemia and rodents, but it can also be transferred to humans via mosquito bites and occasionally tick bites.

Tularemia can be transmitted to people, such as hunters, who have handled infected animals. Infection can also arise from the bite of infected insects (most commonly ticks and deer flies); by exposure to contaminated food, water, or soil; by eating, drinking, putting hands to eyes, nose, or mouth before washing after outdoor activities; by direct contact with breaks in the skin; or by inhaling particles carrying the bacteria (through mowing or blowing vegetation and excavating soil).

Typical signs of infection in humans may include fever, chills, headache, swollen and painful lymph glands, and fatigue. If tularemia is caused by the bite of an infected insect or from bacteria entering a cut or scratch, it usually causes a skin ulcer or pustule and swollen glands. Eating or drinking food or water containing the bacteria may produce a throat infection, mouth ulcers, stomach pain, diarrhea and vomiting. Inhaling the bacteria may cause an infection of the lungs with chest pain and coughing.

Tularemia can be effectively treated with antibiotics. Untreated tularemia can lead to hospitalization and may be fatal if not diagnosed and treated appropriately.

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For more:  https://madisonarealymesupportgroup.com/2016/10/25/of-rabbits-and-men/

https://madisonarealymesupportgroup.com/2019/02/18/tularemia-in-minnesotan-ticks/

https://madisonarealymesupportgroup.com/2019/08/23/ticks-are-one-way-tularemia-can-be-spread-rabbits-are-another/

https://madisonarealymesupportgroup.com/2018/09/28/after-tularemia-death-experts-stress-education/

https://madisonarealymesupportgroup.com/2018/02/27/tularemia-infected-ticks-found-on-sorrento-valley-trail-in-ca

https://madisonarealymesupportgroup.com/2018/09/19/glandular-tularemia/

 

Ticks Are One Way Tularemia Can Be Spread. Rabbits Are Another

https://www.lymedisease.org/tularemia/

Ticks are one way tularemia can be spread. Rabbits are another.

North Central Integrated Pest Alert

https://www.ncipmc.org/projects/pest-alerts1/

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They have the following for ticks and specific diseases:

https://www.ncipmc.org/projects/pest-alerts1/brown-dog-tick-vector-for-rocky-mountain-spotted-fever/

https://www.ncipmc.org/projects/pest-alerts1/rocky-mountain-spotted-fever-rickettsia-rickettsii/

https://www.ncipmc.org/projects/pest-alerts1/ticks-and-tick-borne-diseases/

 

Other Arthropod-Borne Bacteria Causing Nonmalarial Fever in Ethiopia

https://www.ncbi.nlm.nih.gov/pubmed/31184993/

2019 Jun 10. doi: 10.1089/vbz.2018.2396. [Epub ahead of print]

Arthropod-Borne Bacteria Cause Nonmalarial Fever in Rural Ethiopia: A Cross-Sectional Study in 394 Patients.

Abstract

Bacterial arthropod-borne pathogens are a common cause of fever in Africa, but their precise impact is unknown and usually underdiagnosed in the basic rural laboratories of low-resourced African countries. Our aim was to determine the prevalence of arthropod-borne bacterial diseases causing fever among malaria smear-negative patients in a rural hospital located in Ethiopia. The study population included patients aged 2 years or older; referred to Gambo Rural General Hospital (West Arsi, Ethiopia), between July and November 2013, for fever or report of fever in the previous 48 h; attending the outpatient department; and testing negative for malaria by Giemsa-stained thin blood smears. We extracted DNA from 394 whole blood samples, using reverse line blot assays of amplicons to look for bacteria from the genera: Anaplasma, Bartonella, Borrelia, Coxiella, Ehrlichia, Francisella, and Rickettsia.

Thirteen patients showed presence of DNA for these pathogens: three each by Borrelia spp., the Francisella group (F. tularensis tularensis, F. tularensis holartica, and F. novicia), Rickettsia bellii, and Rickettsia Felis, and one by Bartonella rochalimae. Thus, in this rural area of Africa, febrile symptoms could be due to bacteria transmitted by arthropods. Further studies are needed to evaluate the pathogenic role of R. bellii.

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**Comment**

What if some of this is mosquito-borne as well? We frankly don’t know because the transmission studies are screaming to be done.

https://madisonarealymesupportgroup.com/2018/11/07/are-mosquitoes-transmitting-lyme-disease/

https://madisonarealymesupportgroup.com/2018/02/12/wolbachia-laced-mosquitoes-being-released-why-lyme-msids-patients-might-be-negatively-affected/