Archive for the ‘Lyme’ Category

Global Lyme Alliance Doing Kick-butt Research

https://globallymealliance.org/press-releases/global-lyme-alliance-reveals-several-drugs-drug-combinations-show-success-treating-lyme-disease/?

GLA’S PIONEERING RESEARCH FUNDING STRATEGY RESULTS IN PROMISING OUTCOMES THAT HELP PATIENTS SUFFERING FROM LONG-TERM LYME DISEASE

STAMFORD, CONN (April 12, 2019)—Global Lyme Alliance’s commitment to identify and fund innovative and promising Lyme disease research is unrivaled. A vital component to GLA’s leadership role in Lyme disease research is its success with early-stage funding. Discovering and supporting researchers who are new to Lyme but bring years of relevant disease work or are at the beginning of their careers, helps distinguish GLA’s approach to finding the evidence-based answers that will ultimately help patients.

In 2009, on a limited research budget, GLA had decided to proactively recruit scientists and fund research in new areas to further the understanding of Borrelia burgdorferi (the Lyme bacteria) that could lead to an improved diagnostic test and ultimately, a cure, for Lyme disease. GLA’s objectives were to:

  1. determine if the antibiotic evading technique of bacteria, like Escherichia coli, is being used by the Lyme bacteria and therefore explain the typical patient experience of symptom improvement followed by symptom relapse
  2. determine if such persistent or dormant cells were protected within biofilms
  3. identify existing drugs from a vast FDA library and find novel new treatments to eliminate persister (non-growing) and growing Lyme bacteria which could be a cure
  4. identify the surface proteins of the persister form of the bacteria to improve the current diagnostic tests. The first step in achieving these objectives was to fund a study conducted by Ying Zhang, M.D. at Johns Hopkins University in early 2010, to see if the Lyme bacteria could form persister or dormant cells in the test tube; and if they did, to proceed with the other aforementioned aims

Based on early findings of the Zhang/Johns Hopkins study that showed that the Lyme bacteria could ‘morph’ into persisters, GLA then recruited Kim Lewis, Ph.D., Director of the Antimicrobial Discovery Center at Northeastern University, who is an expert in the area of bacterial persistence and antibiotic tolerance. GLA worked with Dr. Lewis on developing a multi-year study design and agreed to fund it. This study would ultimately confirm the ability of Lyme organisms to become persisters and went on to then find existing and new drugs to kill these persister (non-growing) forms. Both Northeastern and Johns Hopkins were running parallel, independent experiments and drug discovery protocols backed by GLA.

By 2018, Dr. Ying Zhang and his team at Johns Hopkins made significant strides:

  • Confirmed the existence in vitro of the dormant, persister Lyme bacteria
  • Showed how the Lyme bacteria goes dormant and changes its protein composition and shape when exposed to antibiotics and then grows again when antibiotic treatment is stopped
  • Identified its protein components and a new diagnostic tool to recognize persistence in patients
  • Used high-throughput drug discovery and drug efficacy testing programs
  • Identified a powerful combination of Daptomycin + Cefuroxime + Doxycycline to eliminate growing and non-growing forms of the bacteria and identified essential oils from spice and culinary herbs (g., oregano, cinnamon bark, and clove bud) which also serve to eliminate persister bacteria as well as biofilm-like forms

By 2018: Dr. Kim Lewis and his team at Northeastern University, independently, also made considerable findings:

  • Confirmed the existence in vitro of the dormant, persister Lyme bacteria
  • Showed how the Lyme bacteria goes dormant when exposed to antibiotics and then springs back to a form capable of growing again
  • Using a separate drug screening tool, identified Daptomycin, Mitomycin C (an anticancer agent) and Ceftriaxone as a possible drug combination to eliminate dormant and growing cells
  • Discovered through Dr. Lewis’ pipeline discovery program that Disulfiram, used for treating alcoholism, was extremely effective in culture and in mice in to killing burgdorferi in all forms
  • Discovered an antibiotic through his proprietary approach to screen soil bacteria, known as Hygromycin A that could kill the Lyme bacteria in vitro and in mice
  • Proved that in vitro, Vancomycin was more powerful in clearing all forms of the Lyme bacteria than Doxycycline

The complete path from initial seed funding to results that will impact patients follows.

GLA Initial Seed Funding (2013)

  • GLA is the first to identify Dr. Lewis as a scientific expert looking at bacterial persister cells, antibiotic tolerance, and novel therapies who could apply his knowledge to the study of Lyme disease
  • GLA helps design and funds Dr. Lewis’ multi-year study, “Persister Cells and Antibiotic Tolerance in Bb” to investigate whether burgdorferi forms antibiotic-tolerant persister forms

GLA Annual Lyme Disease Research Symposium (2014)

  • In 2014, through regular progress reports to GLA Scientific Advisory Board and presenting at GLA’s annual Lyme Disease Research Symposium, Dr. Lewis shares his initial findings from GLA-funded study. At the Symposium are other top scientists, including Dr. Brian Fallon, Dr. Armin Alaedini, and Dr. John Aucott
  • Lewis finds that B. burgdorferi can go dormant to evade antibiotics and then restart replication once antibiotics are removed. He had then performed an initial screen of FDA drugs for novel compounds that could target persister forms of the Lyme bacteria
  • Lewis was honored at Global Lyme Alliance Greenwich Gala, along with Ying Zhang, M.D., Ph.D., of Johns Hopkins University for their work in discovering Borrelia persisters

Published Findings (2015): The Lyme bacteria morphs to evade antibiotics

  • Lewis publishes landmark paper on persisters in Antimicrobial Agents and Chemotherapy, “Borrelia burgdorferi, the Causative Agent of Lyme Disease, Forms Drug-Tolerant Persister Cells”, based on GLA funding from 2013. He showed that antibiotics killed most lab-grown B. burgdorferi, with a small surviving population that tolerated drug treatment. His team found that Mitomycin C efficiently killed persisters
  • Lewis noted that persisters play dead and then reawaken once treatment is completed in the context of recurrent urinary tract infections. “They start multiplying again, he explains, “and you get this relapsing, chronic infection.” It is possible a similar situation and explanation exists for chronic Lyme disease; however, more research is needed to test this hypothesis

GLA Fosters Collaboration & Continues Funding (2016, 2017, 2018)

  • In 2016, GLA funds Dr. Lewis’ well-regarded study “Discovery of new antibiotics and combinations”
  • Initial findings include results using Disulfiram (an FDA-approved drug for the treatment of chronic alcoholism and Hygromycin A (an antibiotic derived from soil bacteria)
  • In 2017 and 2018, a top Lyme-treating physician starts implementing Dr. Lewis’ findings using Disulfiram to treat post-treatment Lyme disease patients. To date, on a limited number of patients, Disulfiram is proving very promising
  • GLA-funded researcher and Lyme-treating physician Dr. Brian Fallon of Columbia University designs a clinical study to determine therapeutic efficacy of Disulfiram in 2019
  • Thanks to four years of financial backing by GLA, Dr. Lewis is able to deliver ground-breaking discoveries in Lyme disease, in particular, persisters and novel treatments, enabling him to attract attention from additional private foundation donors. This enables Dr. Lewis greater opportunity to investigate new therapies for chronic Lyme patients

Published Findings (2018): Vancomycin is the strongest antibiotic in treating Lyme disease

  • In 2018, Dr. Lewis publishes important paper on novel therapies in Antimicrobial Agents and Chemotherapy, “Identifying Vancomycin as an Effective Antibiotic for KillingBorrelia burgdorferi“, based on GLA funding.
  • Lewis’ team found that Vancomycin was effective against in vitro cultures of growing B. burgdorferi. However, this class of drugs is not expected to work on stationary persister cells, in which growth is very slow, and cell wall synthesis is expected to be minimal. Unexpectedly, when tested on stationary B. burgdorferi, they found that cell wall synthesis still occurred, and could be blocked by Vancomycin.
  • To extend their studies to an in vivo model, the group treated burgdorferi-infected, immunodeficient mice for five days. They found that Vancomycin and Ceftriaxone each completely blocked bacterial growth, compared with partial eradication by Doxycycline. These studies suggest that more effective antimicrobial drugs, used early in infection, may prevent or reduce the occurrence of persisting infection.

Clinical Trials & Helping Patients (2019)

  • In 2019, GLA helps facilitate clinical trials leveraging Dr. Lewis’ findings with respected Lyme-treating physicians. Clinical trials performed under the guidance of GLA’s rigorous peer-reviewed process will ensure valid results, to most effectively impact patients.

Lyme disease is extremely complex, and the challenge to understand it and ascertain how to most successfully treat patients impacted by it is a herculean task. Through an aggressive and innovative research strategy, backed by a world-renowned Scientific Advisory Board and top-notch in-house science team, GLA is finding the answers.


About Global Lyme Alliance
Global Lyme Alliance is the leading 501(c)(3) organization dedicated to conquering Lyme and other tick-borne diseases through research, education and awareness. GLA has gained national prominence for funding some of the most urgent and promising research in the field, while expanding education and awareness programs for the general public and physicians. We support those around the globe in need of information about tick-borne diseases. Learn more at GLA.org.

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**Comment**

Credit should be given where credit is due.  GLA is kicking butt in the world of Lyme/MSIDS research.

Currently, Disulfiram is being used on numerous Lyme/MSIDS patients in Mexico and many more in the U.S. with pretty astounding results. The herxes can be surreal so it takes an experienced practitioner, but, it has action against  malaria, HIV, cancer and Lyme (borrelia):

Malaria:

HIV:

Cancer:

Lyme (borrelia):

Do not self-treat. Talk to your practitioner about these findings and work with him/her.  While Disulfiram (Antabuse) is cheap, it can cause vast die-off and an inflammatory response that could put you in the ER.

Is Lyme Disease Sexually Transmitted?

https://www.bca-clinic.de/en/is-lyme-disease-sexually-transmitted/

Is Lyme Disease Sexually Transmitted?

Lyme disease is primarily transmitted by ticks; that much most people know. The link between the words ‘Lyme’ and ‘ticks’ is cemented in the public consciousness, so much so that in 2018, many will instinctively conjure images of ticks when they hear or read something concerning Lyme disease. This is certainly progress. The enigmatic disease was only discovered a mere 43 years ago, although it has been around for centuries. Since its discovery in the town of Old Lyme, Connecticut, the disease has had a hard time being taken seriously, or at least being considered as the debilitating threat it undoubtedly is. Now that Lyme is finally becoming more visible in the mainstream medical community, patients and doctors alike are looking at ways it can be transmitted. One of the areas up for discussion is the possibility of sexual transmission.

Many severe and extreme conditions can be transmitted sexually, and everyone is aware of the dangers of prominent STDs like AIDS, HIV, syphilis, gonorrhoea and herpes. But could Lyme disease also join the line-up of threats? It was previously thought that any type of human-to-human Lyme transmission was impossible, and only specific types of tick could spread the disease. Borrelia burgdorferi is the bacteria responsible for causing Lyme; it’s carried by deer ticks in North America, and sheep ticks in Europe. It is estimated that as many as one in three ticks are contaminated with Borrelia, making the likelihood of catching Lyme in tick-populated areas quite high. Many people dismiss Lyme disease as they believe it’s easy to tell if you’ve been bitten by a tick or not. However, it is not altogether straightforward. Ticks will often seek out sheltered or hard-to-reach places on the human body before biting, and their saliva is laced with a paralytic agent that further minimises the risk of detection.

BCA-clinic - couple
While the medical community put a lot of effort into researching, treating and attempting to cure common STDs, the research into whether Lyme disease can be sexually transmitted is very limited.

The appearance of a distinctive bullseye rash is one of the most concrete indicators of Lyme disease, although it can be quite hard to spot, and never appears in the first place in a minority of cases. This rash is accompanied by flu-like symptoms as the disease spreads in its acute stage. When these symptoms subside, the bacteria settle into the body, and the condition mutates into its chronic stage, which is notoriously hard to both diagnose and treat, and remains a point of contention between Lyme experts and other medical professionals. If the offending bacteria remains in a person’s system for many years, then it’s logical to assume that they can potentially transmit Lyme disease to their sexual partner(s) at any point during the prolonged infection. Therefore, it’s crucial to know if and how this type of transmission is possible.

According to the CDC (the Centres of Disease Control and Prevention), the case is crystal clear: their website officially states that ‘there is no credible scientific evidence that Lyme disease is spread through sexual contact’, going so far as to say that ‘the biology of the Lyme disease spirochete is not compatible with this route of exposure’. However, the CDC hasn’t got a great track history of Lyme expertise. Their position on the chronic form of Lyme is still a grey area at best, and their website also states that, in relation to the transmission of Lyme disease from mother to child during pregnancy, ‘no negative effects on the foetus have been found’. In fact, the transmission of Lyme during pregnancy is well-documented by Lyme experts and researchers, and although it’s a rare scenario, it is still possible.

BCA-clinic
The CDC say that there is no discernible evidence that Lyme disease can be sexually transmitted, experts have theorised that it is a possibility.

So how do the experts see it? Dr. Carsten Nicolaus, head of Lyme specialists BCA-clinic in Augsburg, thinks that the question is not easily answered, and although it’s a probability, the risk seems very low. He cites a study conducted by Marianne Middelveen and Dr. Ray Stricker in 2014, which confirmed the presence of Borrelia burgdorferi in the genital secretions of Lyme-positive heterosexual couples. In one case, a couple was found to secrete an identical strain of Lyme spirochete in their separate samples, strongly indicating that the bacteria can be transmitted through unprotected sex. However, the study conducted is far too small to be of any diagnostic use; although the findings are interesting and alarming, more research and studies need be conducted to produce a concrete answer.

In theory, certainly, sexual transmission of Lyme disease is possible. The corkscrew-shaped Lyme spirochete shares many traits with Treponema pallidum, the microbe that causes syphilis. The latter is well-versed in the sexual transmission pathway, and has honed the method to near perfection. Borrelia has repeatedly been shown to be both opportunistic and insidious in the way it infects and survives in its host; it follows that if the opportunity for a new method of infection arose, it would almost certainly take it. As Lyme disease becomes more visible all over the world, it is important to remember that we know startlingly little about it, in comparison to other disorders. As such, it is crucial that meticulous study and tests continue, so we can rule out certain methods of transmission, or devise new ways to fight them.

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**Comment**

Although this was written 4 months ago, it still demands an answer.

Isn’t it interesting that the small 2014 study barely raised eye-brows except for in the Lyme world?  That should tell you something right away.

Authorities don’t want to know the answer to this question because first they’d have to admit stupidity & that they were wrong, and second, they’d have to do something about it….and heaven forbid either of those two things happen.

I’m quite open about the fact I believe I got this STD from my infected husband. All my initial symptoms were gynecological, it’s just I didn’t know anything about Lyme/MSIDS at the time. I went down the rabbit-hole of transmission fairly quickly in my journey due to my own case and I write about it, with tons of links to studies and experts disagreeing with the accepted narrative here: https://madisonarealymesupportgroup.com/2017/02/24/pcos-lyme-my-story/

Nothing is going to happen unless we demand it to happen. I find it highly interesting that at the first whiff of Zika being sexually transmitted, authorities followed through and it was the shot heard around the world – even though mosquitoes can’t even carry it in Wisconsin and many, many other states.

Here’s the map of places in the U.S. where the mosquitoes capable of transmitting Zika live:

skeetermap_3d30eb2906fee062c217d550899919fa.fit-560w

Here’s where the black legged tick able to transmit Borrelia burgdorferi and B. mayonii (which cause Lyme disease), Anaplasma phagocytophilum (anaplasmosis), B. miyamotoidisease (a form of relapsing fever), Ehrlichia muris eauclairensis (ehrlichiosis), Babesia microti (babesiosis), and Powassan virus (Powassan virus disease) lives:

lgmap-blacklegged_tick

Here’s where the American dog tick capable of transmittingTularemia and Rocky Mountain spotted fever lives:

CS4_Tick Basemap_v8.ai

Here’s where the brown dog tick capable of transmitting Rocky Mountain spotted fever lives:

CS4_Tick Basemap_v8.ai

Here’s where the lone star tick capable of transmitting Ehrlichia chaffeensis and Ehrlichia ewingii(which cause human ehrlichiosis), Heartland virus, tularemia, and STARI live:

lgmap-lone_star_tick-2

Here’s where the Rocky Mountain wood tick capable of transmitting Rocky Mountain spotted fever, Colorado tick fever, and tularemia lives:

CS4_Tick Basemap_v8.ai

Here’s where the Gulf Coast tick capable of transmitting Rickettsia parkeri rickettsiosis, a form of spotted fever lives:

CS4_Tick Basemap_v8.ai

And lastly, where the Western black-legged tick capable of transmittingAnaplasmosis and Lyme disease lives:

CS4_Tick Basemap_v8.aiTick distribution maps found:  https://www.cdc.gov/ticks/geographic_distribution.html

In total – 7 types of ticks spreading deadly diseases in every single state in the U.S. but we know more about a tropical disease that in 80% of those who contract it have ZERO symptoms, and 1 out of 5 will have mild symptoms that last a week.  https://madisonarealymesupportgroup.com/2016/12/21/how-zika-got-the-blame/. Call me crazy, but the disparity of risk between the two diseases couldn’t be greater.

Not to mention that migrating birds are transporting ticks worldwide:

https://madisonarealymesupportgroup.com/2019/03/09/danish-study-shows-migrating-birds-are-spreading-ticks-their-pathogens-including-places-without-sustainable-tick-populations/

https://madisonarealymesupportgroup.com/2019/04/11/african-tick-found-on-untraveled-u-k-horse/

https://madisonarealymesupportgroup.com/2018/06/08/hemorrhagic-fever-virus-found-on-ticks-on-migratory-birds/

https://madisonarealymesupportgroup.com/2017/08/17/of-birds-and-ticks/

https://madisonarealymesupportgroup.com/2016/10/02/the-role-of-birds-in-tickborne-illness/

https://madisonarealymesupportgroup.com/2018/11/05/hawk-found-carrying-asian-long-horned-tick-the-one-that-drains-cattle-of-all-their-blood/

I literally could go on and on with this….

Time to focus on things that are side-lining Americans.

NY TV Reporter Tells Her Own Lyme Disease Story

https://www.lymedisease.org/new-york-tv-reporter-tells-her-own-lyme-disease-story/

New York TV reporter tells her own Lyme disease story

https://www.localsyr.com/news/local-news/living-with-lyme-newschannel-9-reporter-nicole-sommavilla-opens-up-about-her-health-journey/1914141778

4 Min News Video here of Ms. Sommavilla’s story.  

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**Comment**

Again, we need to keep sharing our stories until authorities listen and change things.  Another great example of a person who NEVER saw the tick or rash.  With all the people I work with – hardly anybody does, yet they make it sound as if it’s a prerequisite.  Please know the percentages seeing the rash very from 27-80% – hardly a sure thing:  https://madisonarealymesupportgroup.com/2019/02/22/why-mainstream-lyme-msids-research-remains-in-the-dark-ages/  And in the 1st ever patient group in Lyme, Connecticut, only a quarter had the rash.

Notice how severe this case is.  I assure you there are thousands more just like this that never got the proper diagnosis.

Thank God for doctors WHO USE THEIR GOD-GIVEN BRAINS!

For a wonderful 5-part series by NBC NY on Lyme/MSIDS:

https://madisonarealymesupportgroup.com/2017/10/24/lyme-wars-part-1-julias-story/

https://madisonarealymesupportgroup.com/2017/10/25/lyme-wars-part-2-kyra-overcomes-chronic-lyme-diagnosis/

https://madisonarealymesupportgroup.com/2017/10/26/lyme-wars-part-3/

https://madisonarealymesupportgroup.com/2017/10/27/lyme-wars-part-4/

https://madisonarealymesupportgroup.com/2017/10/28/lyme-wars-part-5-coinfections/

 

Neuro-Lyme is Like Hitting My Head Against a Fog Wall

https://www.lymedisease.org/starling-fog-wall/

Neuro-Lyme is like hitting my head against a fog wall

April – Lyme Prevention Month for Dogs: A Pet Owner’s Guide

https://www.avma.org/public/PetCare/Pages/lyme-disease.aspx

Lyme Disease: A Pet Owner’s Guide

Rolo
Rolo has Lyme disease, but thanks to early diagnosis and regular veterinary care, she lives a happy, healthy life with her family.
Lyme disease (Lyme borreliosis) is an illness that affects both animals and humans – what is known as a zoonotic disease – and is the most commonly reported vector-borne illness in the United States, according to the U.S. Centers for Disease Control and Prevention (CDC). Transmitted through tick bites, the disease can be difficult to detect and can cause serious and recurring health problems. Therefore, it is best to prevent infection by taking appropriate measures to prevent tick bites and, for dogs, possibly vaccinating against the disease.

 

The bacterium that causes Lyme disease – a worm-like, spiral-shaped bacterium called Borrelia burgdorferi  – is carried and transmitted primarily by the tiny black-legged tick known as the deer tick. Deer ticks are found in forests or grassy, wooded, marshy areas near rivers, lakes or oceans. People or animals may be bitten by deer ticks during outdoor activities such as hiking or camping, or even while spending time in their back yards. 

Named after numerous cases were identified in Lyme, Conn., in 1975, the disease has since been reported in humans and animals across the United States and around the world. Within the U.S., it appears primarily in specific areas including the southern New England states; eastern Mid-Atlantic states; the upper Midwest, particularly Wisconsin and Minnesota; and on the West Coast, particularly northern California. The CDC maintains a map detailing confirmed cases of Lyme disease throughout the years.

Lyme disease is a reportable disease – which  means that health care providers and laboratories that diagnose cases of laboratory-confirmed Lyme disease are required to report those cases to their local or state health departments, which in turn report the cases to the CDC.

How to prevent Lyme disease

The best way to protect pets from Lyme disease is to take preventive measures to reduce the chance of contracting the disease. Even during the last weeks of summer, it’s important to remember that pets and people are at greater risk of being infected with Lyme disease and other tick-borne diseases such as anaplasmosis, ehrlichiosis, or Rocky Mountain Spotted Fever.

People with pets should:

  • Use reliable tick-preventive products. Speak with your veterinarian about what tick preventive product is right for your pet.
  • Work with your veterinarian to decide whether to vaccinate your dog against Lyme disease. Your veterinarian’s advice may depend on where you live, your pet’s lifestyle and overall health, and other factors.
  • When possible, avoid areas where ticks might be found. These include tall grasses, marshes and wooded areas.
  • Check for ticks on both yourself and your animals once indoors.
  • Clear shrubbery next to homes.
  • Keep lawns well maintained.

As noted above, there are preventive Lyme disease vaccines available for dogs, but they aren’t necessarily recommended for every dog. Consult your veterinarian to see if the vaccination makes sense for your pets. If your veterinarian does recommend that your dog be vaccinated against Lyme disease, the typical protocol will involve an initial vaccination followed by a booster 2-4 weeks later and annual boosters after that.

Lyme disease in pets – symptoms and treatment

Pets infected with Lyme disease may not show any signs for 2-5 months. After that time, typical symptoms include:

  • Fever
  • Loss of appetite
  • Lameness
  • Joint swelling
  • Decreased activity

Recurrent lameness also is possible, and the involved extremity may be tender. Inflammation of the joint can last from days to weeks, and may migrate from one extremity to another.

Horses with Lyme disease can develop lameness, joint pain, neurologic disease, eye problems and dermatitis.

Symptomatically, Lyme disease can be difficult to distinguish from anaplasmosis because the signs of the diseases are very similar, and they occur in essentially the same areas of the country. Lyme disease is diagnosed through a blood test that shows whether an animal has been exposed to the bacterium.

Antibiotics usually provide effective treatment for Lyme disease. However, it’s important to follow your veterinarian’s advice regarding follow-up care after your pet has been diagnosed with and treated for the disease.

Lyme disease is not communicable from one animal to another, except through tick bites. However, if you have more than one pet and one is diagnosed with Lyme disease, your veterinarian might recommend testing for any other pets who may have been exposed to ticks at the same time. In fact, because people and their pets often can be found together outdoors as well as indoors, a Lyme disease diagnosis in any family member – whether human or non-human – should serve as a flag that all family members might consult their physicians and veterinarians, who can advise about further evaluation or testing.

It’s a “One Health” problem

Because people and their pets often spend time in the same environments where Lyme and other disease-transmitting ticks are found, the American Veterinary Medical Association (AVMA) and the American Academy of Pediatrics (AAP) are working together to offer advice to households with both children and pets. People who have been diagnosed with Lyme disease should consult their veterinarian to determine their pet’s risk based on the animal’s lifestyle and possible environmental exposures. Likewise, people whose animals have been diagnosed with Lyme disease may want to consult their physician about their own or their children’s risk if they have concerns that the animals and family members might have been exposed to similar environmental risks.
Thousands of cases of Lyme disease have been reported in humans and animals across the United States and around the world. By knowing about Lyme disease and how to prevent it, you can help keep all members of your family — human and animal — safe.

Lyme disease in people

In humans, often the earliest indication of infection is a “bullseye” rash at the site of the tick bite – so named because it resembles a target. As the infection develops, symptoms include fever, headache, fatigue, and muscle and joint pain. The disease can progress to cause chronic joint problems as well as heart and neurological problems. As with pets, Lyme disease is not contagious from one person to another.

There are many things people can do to avoid exposure to tick bites. These include:
  • Avoid areas where ticks are found
  • Cover arms, legs, head and feet when outdoors
  • Wearilight-colored clothing
  • Use insecticides
  • Checking for ticks once indoors.

The American Academy of Pediatrics has more information about Lyme disease in people.

Related information

More from other sources

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**Comment**
  1. Our dog’s case of Lyme disease was picked up on a yearly routine test. He was fine and didn’t show any signs of infection. Our vet insisted that he be treated with over a month’s worth of antibiotics. Meanwhile, my husband spiraled down the vortex of doom for years. No blood test would pick it up. He tested negative on the two-tiered CDC testing. Thankfully, a wise “out of the box” doctor tested him for inflammation which was off the charts high. She said, “The CDC says you don’t have Lyme, I say you do,” and she treated him with two antibiotics – of which he improved immediately. Shortly after, I developed symptoms but also tested negative with CDC testing. By this time, I contacted a Lyme support group and became educated on the polarization within the medical community and had the list of WI LLMD’s in hand. We’ve been in and out of treatment ever since, having spent over $150K out of pocket, but have our lives back.
  2. Throw the CDC maps in the garbage.  This is a pandemic and in every continent but the Antarctica.
  3. Far fewer are getting the EM rash than is touted:  https://madisonarealymesupportgroup.com/2019/02/21/lyme-disease-dont-wait-for-blood-tests-where-patients-have-bullseye-rash/ (read comment as well)
  4. Read up on the Lyme vaccine.  It caused Lyme-like symptoms in people and it’s done that to animals as well: https://www.dogsnaturallymagazine.com/lyme-vaccine-dogs/
  5. While authorities keep saying this can’t be transmitted person to person, Lida Mattman PhD has gone on record saying something entirely different and she studied spirochetes for decades: https://madisonarealymesupportgroup.com/2019/04/02/transmission-of-lyme-disease-lida-mattman-phd/
  6. There’s more than Lyme to worry about:  https://madisonarealymesupportgroup.com/2018/10/30/study-shows-lyme-msids-patients-infected-with-many-pathogens-and-explains-why-we-are-so-sick/
  7. For more on prevention:   https://madisonarealymesupportgroup.com/2019/04/12/tick-prevention-2019/

WLN Newsletter – April, 2019

At_a_Glance_Newsletter_4-16-19

Highlights

  • Recap of March WLN Lyme Workshop held in La Crosse. Over 60 from across the state attended!
  • Great article by WLN president Sherry Sievewright on  the importance of addressing microbes in Lyme/MSIDS treatment.
  • WI Lyme Walk for 2019 tabled.
  • Permethrin Pretreated Socks for sale to raise funds for WI doctor education.
  • Upcoming Lyme Awareness Event in Madison:

Mark Jason Lim

 

‘Horror’ Summer of Blood-sucking Ticks That Can ‘Cripple and Blind You’ On its Way

https://www.mirror.co.uk/news/uk-news/horror-summer-blood-sucking-ticks-14235057

‘Horror’ summer of blood-sucking ticks that can ‘cripple and blind you’ on its way

A five-year-old boy from Llandudno, in Wales, has already caught Lyme disease and the Health Protection Agency say case numbers are soaring

By Jim Hardy & Libby McBride

If a bug latches on to a human it can pass on a germ which can cause blindness, paralysis and meningitis (Image: WESSEX NEWS AGENCY)

Britain could be in for a record-breaking “horror” summer of blood-sucking ticks which can cripple people and even make them blind.

Following a mild winter and with the balmy weather this spring, fears are growing that the insects could have survived their hibernation in vast numbers and could be ready to breed and multiply.

The ticks spread Lyme disease with their saliva as they gorge on people’s blood – but it’s incredibly early in the year for an outbreak.

If a bug latches on to a human it can pass on a germ which can cause blindness, paralysis and meningitis .

The nightmare vampire-like mites, which feast on flesh, have already left a five-year-old boy suffering from Lyme disease .

Doctors are monitoring William Bargate who was bitten twice within five days by two separate ticks after playing at a Conwy Council owned park in Llandudno, Wales.

Three days after the initial tick bite on March 22 – which is understood to have been attached to William’s head for up to 36 hours – he began to suffer flu-like symptoms including tiredness, muscle pain, headachesand a fever.

Open-air lovers are warned that sex in the grass could have consequences (Image: WESSEX NEWS AGENCY)

His mother Adelle Bargate, 37, took him to see a doctor but says that as he did not have the visible circular rash associated with the disease it was thought he had just contracted a viral infection.

But days later, William was taken to see the doctor for a second time after being bitten again.

As well as being unable to move his neck, he had also developed severe and worsened flu-like symptoms.

The disease most commonly affects the skin, joints, the heart and the nervous system and is generally treated with antibiotics but some patients claim the symptoms can continue after treatment.

William Bargate, 5, was bitten by two ticks (Image: Daily Post/Adelle Bargate)

“On the second visit, the doctor acknowledged the potential infection and gave him 10 days worth of antibiotics” Ms Bargate said.

“But his symptoms were worsening and I was really concerned so I took him to A&E in Bangor on Saturday.

“They took him straight to the children’s ward where he was immediately sent for blood tests and that’s when they said they were treating it as Lyme disease.

“It’s really difficult to get a positive test of Lyme disease so as a precaution to his nasty symptoms he is now on a three week course of antibiotics.”

William was discharged from hospital on Sunday with three weeks worth of antibiotics, and his mum was told he will need to go for further tests this week to monitor the suspected disease.

A tick gorged with blood (Image: WESSEX NEWS AGENCY)

Mum Adelle continued:

I’ve lived on the Orme for more than 16 years and I never had ticks pulled off me as a child, it only seems to have become a bigger problem over the last two years.

“I don’t think it’s being taken seriously enough in the area, I feel as though I am the only person who is making a noise about the number of them around here.

“Nobody seems to be doing anything about it and I’m worried more children will become sick because of them.

“Every time my children play outside I have to strip them and check them for ticks.”

Her son’s illness comes after she also found a tick on her eight-year-old daughter Briony’s head in June last year, which she suspects had been there for around two days.

He was prescribed antibiotics (Image: Daily Post/Adelle Bargate)

It was the second tick she had found on her daughter in a week.

At the time, a number of families also reported finding the tiny blood sucking insects attached to their child’s skin after they were playing in and around the same park.

Public Health Wales declined to comment due to patient confidentiality.

Now it’s feared that billions of the blood-sucking bugs which can send you blind or cripple you for life are ready to creep across the country.

How to avoid getting bitten by ticks

  • Stick to paths – Try not to stray from paths and avoid overhanging vegetation unless
    necessary. Ticks do not jump or fly so sticking to clear areas without tall
    grass or shrubs will decrease the chances of being bitten. If in an area
    where there is no footpath, try and avoid tall grass or shady areas that are
    surrounded by shrubs.
  • Light Clothing – When in areas of woodland remained covered, wear long sleeve tops and full-length trousers. Protect areas such as the back of the knees, armpits
    and the groin area. Opt for light coloured clothing in order to easily
    identify any ticks present that may become attached.
  • Footwear – Wellies are not only reserved for rainy days and are perfect when in high risk areas, as you can tuck trousers into the wellie boots. Tucking trousers
    into socks is also a great defence mechanism if wellies are not an option.
  • Regular checks – Ticks are very small and hard to identify when not paying attention. Check regularly whilst outside and also when home in order to remove any feeding ticks. The longer a tick is left attached the harder it is to remove.
  • Right tools – Avoid any home remedies to try and remove ticks such as covering the
    affected area of the body in Vaseline or nail varnish or even burning them
    off. Instead, use a tick removal tool, which are sold in outdoor shops and some
    supermarkets and pharmacies. This will help avoid aggravating the tick and
    lower the risk of secondary infection. When removed, use an antiseptic wipe
    and be aware of any symptoms of Lyme disease

They love to lurk in lush long grass and woodland glades, so couples getting frisky in the fresh air face getting bitten.

The Health Protection Agency says there are 2,000 cases of Lyme disease every year in the UK, but the number is soaring.

TV Question of Sport star Matt Dawson, the former England rugby international, needed heart surgery after he was bitten by a tick in a London park in 2015 and Lyme Disease spread through his body.

Matt Dawson on This Morning
Matt was bitten by a tick while walking in a park in 2016 (Image: Rex)

According to The Big Tick Project – a nationwide research survey in collaboration with Bristol University that looks at the number of ticks on dogs – the numbers are on the increase for several reasons.

“Many factors may have contributed to the increase in tick numbers across the UK” they said.

“Changing weather patterns mean prolonged periods where conditions are favourable for tick survival, particularly wetter summers and warmer winters.

“A lack of awareness amongst pet owners, leading to inadequate treatment and prevention may also play a significant role in contributing to problems for dogs.

“However, despite the growth of tick populations across the country, only 12 per cent of people are actually concerned by the risk posed by ticks.

“More worryingly, 47 per cent of pet owners were not aware that they too are at risk of infection from tick-borne diseases.”

Last summer mum Emily Porter warned parents to be on their guard after she spotted this tick embedded in her three-year-old son’s scalp after their trip to Lyme Park in Disley, Manchester.

The mum-of-two, from Marple,believes she was lucky to spot the tick so soon and managed to get it out with a tick remover.

She said at the time “I saw it whilst washing his hair. It stood out against the blond.

“I probably wouldn’t have spotted it in my other son’s hair and I only knew what it was as I am on high alert as we have a dog who has had them.

Someone else would have probably thought it was a scab or a bit of dirt as they are so tiny at first.”

In a statement at the time, a spokesperson for National Trust-owned Lyme Park advised visitors to wear long trousers and check themselves afterwards to reduce the risk of infection.

The first symptom when someone is bitten by an infected tick is a red circular ‘bullseye’ skin rash which may subside after a week or two.

A high temperature, muscle and joint pain may then follow.

Most infections are not serious but in extreme cases it can cause paralysis, encephalitis and meningitis.

It is caused by the bacteria Borrelia burgdorferi, found in the digestive system of deer, pheasants and mice.

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For more on prevention:  https://madisonarealymesupportgroup.com/2019/04/12/tick-prevention-2019/

Please know, the number of folks getting the “classic” bullseye EM rash is much smaller than is being touted:  https://madisonarealymesupportgroup.com/2019/02/21/lyme-disease-dont-wait-for-blood-tests-where-patients-have-bullseye-rash/  Read comments at end of article as well.

This whole weather issue is a bunch of bunk. Independent Canadian researcher, John Scott, as proven tick proliferation and therefore the spread of disease has absolutely NADDA to do with the weather:  https://madisonarealymesupportgroup.com/2018/08/13/study-shows-lyme-not-propelled-by-climate-change/

It’s the birds

https://madisonarealymesupportgroup.com/2018/11/07/ticks-on-the-move-due-to-migrating-birds-and-photoperiod-not-climate-change/

And, according to a UW Madison PhD in Climatology, there’s only ONE climate change computer model even slightly close to the truth and it shows the least amount of “change.”  He also claims the debate over climate change is infused with political games played to create policy.  https://madisonarealymesupportgroup.com/2018/11/17/uw-madison-phd-in-ecological-climatology-climate-change-computer-models-fudged-except-russian-model/

Lyme/MSIDS is hardly the only issue with a political motivation behind it