The gut microbiome consists of a complex set of microbial communities that shape human physiology in multiple ways, both subtle and profound. Two-thirds of the body’s lymphocytes reside in gut-associated lymphoid tissue (GALT) or traverse GALT and return home to other organs. Interaction between gut microbes and GALT creates a basal state of immune activation that starts at the mucosal surface and impacts the entire body. The composition and metabolic activity of intestinal microbes yields effects that promote inflammation and that help resolve inflammation. These effects result from the impact of structural components of microbial cells (e.g., lipopolysaccharides) and metabolites of microbial enzyme activity (e.g., butyrate, hydrogen sulfide).
Recent studies have shown that T-lymphocyte function is especially sensitive to the bacterial composition of the microbiome. The structure and function of the gut microbiome is molded by personal genetics, diet, co-habitation, environmental toxins, hygiene, personal care products, psychosocial stress, intercurrent infections, vitamin D, tryptophan metabolites, nutritional status, medications, herbs, probiotics, and prebiotics. Disturbances in the ecology of the microbiome/host relationship create a condition called dysbiosis, which influences the development and the outcome of many different diseases. The ability to recognize and correct dysbiosis is a skill that can help clinicians improve the outcomes of infectious, allergic, and autoimmune disorders and may aid the immunotherapy of malignancy.
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N-acetylcysteine (NAC) is a powerful antioxidant which contains the amino acid cysteine, a precursor to glutathione, that was approved as a drug in 1963 and has been widely used as a nutritional supplement since it is not found in food. It is also used in prescription form as an antidote for acetaminiphen-induced toxicity as well as for depression, precancers, HIV & AIDS, to alleviate cancer treatment side-effects, and as a mucolytic agent for upper respiratory conditions such as COVID.
The FDA abruptly decided in 2020 that NAC should suddenly require a doctor’s prescription and issued a warning to seven companies who were illegally selling hangover products with NAC in them. Amazon then completely stopped selling it.
The timing of this abrupt decision is suspicious at best, since NAC very well may help lower the risk of COVID and the fact those with glutathione deficiencies have worse outcomes. Many doctors have recommended NAC as part of an early at-home treatment that is safe, cheap, and effective. Within this article is a video where a pulmonologist explains NAC is necessary to reduce the oxidative stress associated with severe COVID and thus may significantly impact the sales of antiviral drugs. Drugs, in fact, which our conflict-riddled public health ‘authorities’ have a stake in.
Natural Products Insider reports, the warning letters stated that NAC could not be “lawfully marketed in dietary supplements because it was first studied as a drug in 1963.” The Council for Responsible Nutrition (CRN) sent a letter in December 2020 to the FDA’s Office of Dietary Supplement Programs describing the position as “legally invalid.”
To appear reasonable, the FDA announced they wanted more information on how NAC has been marketed as a dietary supplement.
Quick to respond, numerous associations have submitted proof to the FDA of numerous NAC-containing products sold pre-DSHEA and that the FDA is misapplying the prior drug-restriction to NAC, and that it can’t be applied retroactively from the date of DSHEA’s enactment. They also submitted comments, countering FDA’s safety concerns, noting that NAC has been in use for decades and that FDA had access in that time to its own Adverse Event Reporting System, to manufacturing facility inspections, and other tools, as well as data from publicly available research studies conducted on NAC or NAC-containing formulations. CRN pointed to data provided by Pure Encapsulations, a brand marketed by Nestlé Health Science, which includes nine years of adverse event data for the company’s supplement containing NAC:
In a press release, Megan Olsen, CRN’s VP and Associate General Counsel, commented:
“The agency’s continued failure to address the singular legal issue on the table is inexplicable. Their refusal to act is causing harm to consumers and businesses.”
A press release summarized The United Natural Products Alliance’s (UNPA) position on the matter as of January 25, 2022:
The FDA appears to be in hot-water these days and is embroiled in yet another fiasco. The FDA has long been accused of corruption, and ties to Big Pharma which has resulted in unsafe pharmaceuticals. Interestingly, while it approves and promotes toxic drugs like remdesivir and COVID injections which aren’t vaccines and have caused more adverse reactions and death than any other vaccine in the history of VAERS, it squashes safe supplements and proven drugs like NAC, vitamins D, C, zinc, and ivermectin which could improve cases and remove the need altogether for COVID injections. If you have less than 4 minutes, go here to listen to Dr. Kory passionately explain the situation. It literally brought tears to my eyes. Doctors who are truly attempting to help patients are bullied, censored, and shouted down. Kory’s frustration is tangible.
The current top-down, “one-sized fits all” approach to medicine puts everyone into a 4-cornered box regardless of medical history, health status, and individual needs. I highlight how this current dangerous, singular approach, which also includes mainstream media and Big Pharma colluding with public health officials, is removing our precious medical freedoms in this article, as well as is causing a shortage of medical professionals in the U.S. Front-line workers, who were heroes a year ago but are currently being bullied and summarily dismissed without a job or pay simply for not taking an experimental, fast-tracked gene therapy that doesn’t stop infection or transmission.
Reviewed by Bill Rawls, MD
Medical Director of Vital Plan
To say that your lymphatic system has a lot of responsibility for your well-being is a huge understatement. This intricate “highway” of specialized vessels moves lymphatic fluid from the tips of your toes to the top of your head and to centralized lymph nodes. It helps regulate the balance of all fluid in your body. And its most important function? Detoxification.
It’s the lymph system’s job to pick up and dispose of cellular “trash” like white blood cells, bacteria, viruses, toxins, and other molecular debris from every tissue in your body. That’s crucial, since all cells make waste as a byproduct of their normal processes. “Lymphatic fluid carries all that waste to lymph nodes, which act like garbage disposals to destroy it,” says Dr. Bill Rawls, M.D., Medical Director of Vital Plan.
Unfortunately, there are a number of things that can slow down the system and flow of fluid, resulting in symptoms such as fatigue and sluggishness, brain fog, puffy skin, swollen and stiff joints, chronic headaches, and inflammation. The main cause, says Dr. Rawls, is illness. Which makes sense: There’s simply more cellular junk to dispose of when you’re sick — not unlike how an onslaught of cars during rush hour causes slow traffic.
“Chronic illness, in particular, causes congestion throughout the whole body,” Dr. Rawls explains. “When microbes in tissues are flourishing, and more white blood cells are present trying to kill them, they fill up the lymph nodes, causing the nodes to swell, which backs up the whole system.” But it’s not just chronic illness that impedes lymph flow — even a simple cold can trigger swollen lymph nodes, and part of the reason you feel sluggish may be the extra waste your body is trying to dispose of.
Other key causes of lymph fluid slow-down include lack of physical activity and falling short on water intake. That’s because the lymph system is primarily composed of water — if you’re dehydrated, the fluid slows down and inhibits waste removal from the body. Movement of lymph fluid depends on pressure from breathing and muscle movement to move fluid around. So being sedentary or dehydrated is kind of like construction on the highway — it can slow things down to a crawl.
Meanwhile, maintaining a healthy lymphatic system is one of the best ways to support your immune system by quickly and efficiently ridding your body of garbage — and it’s something we have a lot of control over. “That’s empowering when you can say, ‘I can do these few things every day to help keep the lymphatic fluid flowing and keep myself healthy,’” says Vital Plan health coach Belinda Macri, a yoga teacher, Ayurveda practitioner, and health coach.
Here are some simple, everyday ways to clear up lymphatic congestion in your body and boost your immunity in the process.
While you can find professional therapists who specialize in lymphatic massage to get fluids in motion again, both Macri and Dr. Rawls point to these inexpensive DIY strategies for effectively keeping your lymphatic system moving and your body’s natural detoxification process humming.
A big chunk of your body’s hydration needs should come from water-dense fresh fruits and vegetables, Macri says. This fluid, along with sipping water throughout the day, helps keep your lymphatic “pipes” lubricated and draining properly. For better hydration, Dr. Rawls recommends drinking alkaline water to quell free radicals and decrease inflammation.
Fresh produce and other minimally processed, healthy foods also help maintain a strong gut-blood barrier, which prevents toxins and food irritants from leaking into the bloodstream (aka leaky gut syndrome). The result is less inflammation and a lower potential influx of toxins that might otherwise clog up your lymphatic system.
“At night between 10pm and 2am is when the body naturally goes through a major detoxification process, so make sure you’re allowing the lymphatic fluid the most freedom to move,” Macri says. Garments that dig into skin or are restrictive, especially under the arms or groin area where you have lymph nodes, might partially cut off the natural flow, she says.
Not only do muscle contractions initiated by deep breathing help move lymphatic fluid, the mindfulness practices that go along with deep breathing are some of the best ways to manage stress. And when it comes to factors that congest the lymph system, “Stress is a biggie,” Macri says.
If you can spend a chunk of time each day in meditation — great. But even taking mini time-outs throughout the day to focus on breathing is beneficial. Macri suggests scheduling 5 minutes of time at 10am, 2pm, and 5pm, and using that time to close your eyes and take three to five deep belly breaths. Here’s how to do it:
“When you inhale, simply allow your belly to fully expand out like a balloon,” Macri says. “It’s a huge de-stresser — truly one of the most powerful things you can do.” Indeed, research suggests slow, deep, conscious breathing helps decrease feelings of anxiety in stressful situations, it may lower blood pressure and heart rate, and it can even boost the immune system. A study in the journal Frontiers in Psychology also found that belly breathing reduces stressful feelings and levels of the stress hormone cortisol.
Any sort of movement increases the pressure in lymphatic vessels, which is needed to help manually move the fluid along, Dr. Rawls says. Walking, biking, yoga, tai chi, and qigong are some of his top choices.
“If you’re walking, try moving your arms up and over your head and out to the sides,” Macri says. “Even if you’re at your desk, do some squats and move your arms up and down to get the flow going.”
As for yoga poses, sun salutations are an effective sequence, or try individual poses, she says. Poses that invert a part of your body are especially effective as they recruit gravity to help move fluid. Macri recommends the following:
Rebounding — jumping on a small, circular trampoline — also uses gravity and movement to your lymph’s benefit. A mild aerobic workout, it’s often touted as an effective way to get your heart pumping and your lymph fluid moving.
“As you’re jumping, bring your arms up and over your head to create even more movement,” Macri says. It’s also less strenuous — and easier on joints — than jogging, it may help improve balance, and there’s little technique required. “Just jump and jump,” Macri says.
Dry brushing has long been used for lymphatic drainage and to improve flow. “The pressure on the skin pressurizes the tissues, which helps push fluid through the system,” Dr. Rawls says.
Macri suggests using a natural bristle brush or loofah for the daily ritual, which is traditionally done first thing in the morning or before a shower. It also helps exfoliate skin, stimulate sweat and oil glands, and boost circulation, all of which invigorate the body, she says.
Start by brushing the sole of one foot using swift, upward, and circular strokes. Move up to your ankle, then the front and back of your lower leg. “You always want to brush up, or in the direction of your heart or belly button,” Macri says. Move up to the front and back of your thigh and your hip, and then repeat on the other leg, starting again with the bottom of your foot.
Repeat this practice on each arm, starting at your wrists and moving up to your shoulders, neck, and chest. Then move to your abdomen, and continue to brush toward your heart. “It only takes three to five minutes, and you just feel nice and tingly all over afterward,” she says.
Look to those that are known to help break down, bind to, and dispose of proteins, bacteria, toxins, and other substances that can lead to dysfunctional lymphatic flow, including:
Burdock root: A gentle herbal remedy, burdock root has been used for thousands of years in traditional Chinese medicine to detoxify the blood and boost circulation. It also has a long history of use for clearing lymphatic congestion and enlarged lymph nodes.
Andrographis: This well-known antimicrobial herb contains antiinflammatory properties and is a bitter digestive tonic. Andrographis decreases inflammation, and promotes bile flow, relieving stress on the lymphatic system and facilitating healthy detoxification.
Dandelion root: Like burdock root, dandelion root is known in herbalism as an alterative herb, which means it gently increases elimination of metabolic wastes through all of the major organs of elimination, including the lymphatic system.
Bromelain, papain, and peptidase: All are protein-digesting enzymes, and having these in your system helps break down some of the proteins that contribute to inflammation.
Turmeric: Responsible for the bright yellow color in curry, turmeric helps balance inflammatory responses. Additionally, the curcumin in turmeric has liver-protectant qualities and inhibits oxidative damage caused by solvents, alcohol, medications, or viruses.
Sarsaparilla: Derived from the bark of a thorny vine found in South America, sarsaparilla binds to and helps dispose of endotoxins that are released from microbes during die-off.
Red root: This herb is another one that binds to toxins and flushes the system. A word of caution: red root is a coagulant and can mildly thicken the blood, so it’s best to avoid it if you have a history of cardiovascular disease.
As you can see, detoxing your lymphatic system is a relatively easy and enjoyable way to maintain or restore overall health and wellness. Follow these simple steps, and it won’t be long before you experience a noticeable uptick in energy, focus, and mobility.
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1. Choi, Inhu et. al. “The new era of lymphatic system: No llonger secondary to the blood vascular system.” Cold Spring Harbor Perspectives in Medicine. 2012 Apr; 2(4): a006445.
2. Paul, Gina et. al. “A longitudinal study of students’ perception of using deep breathing meditation to reduce testing stresses.” Teaching and Learning in Medicine. 19:3, 287-292
3. Joseph, Chacko N. et. al. “Slow breathing improves arterial baroreflex sensitivity and decreases blood pressure in essential hypertension.” Hypertension. 2005;46:714-718
4. Bhasin, Manoj K. et. al “Relaxation response induces temporal transcriptome changes in energy metabolism, insulin secretion and inflammatory pathways.” PLOSone 2013 May 1;8(5):e62817
5. Ma, Xiao et. al. “The effect of diaphragmatic breathing on attention, negative affect and stress in healthy adults.” Frontiers in Psychology 2017; 8: 874
I had the opportunity to attend ECO 2021 held online on October 28-30, 2021. ECO stands for Exponential Clinical Outcomes. This is one of the most forward-thinking events I have attended.
The event is the brainchild of Dr. Todd Watts and Dr. Jay Davidson who also created CellCore Biosciences and Microbe Formulas. I’m grateful for their products, and I take several of them daily.
CellCore Biosciences is their practitioner line while Microbe Formulas is their consumer line. While many of the products are available from both companies, there are some differences in some products in terms of formulation or availability in the Microbe Formulas product line.
Disclaimer: Nothing in this text is intended to serve as medical advice. All medical decisions should be made only with the guidance of your own personal licensed medical authority.
Disclaimer: This information was taken as notes during the training course and may not represent the exact statements of the speakers. Errors and/or omissions may be present.
Note: As this information may be updated as any errors are found, I kindly request that you link to this single source of information rather than copying the content below. If any updates or corrections are made, this will help to ensure that anyone reading this is getting the most current and accurate information available. ~ The Better Health Guy