Archive for the ‘Supplements’ Category

Nutrigenomics, Epigenetics, & Stress Tolerance 101 – Rhonda Patrick PhD

Recently I discovered that for $10 you can plug your genetic data into a very practical website http://foundmyfitness.com/ that will help you understand your genetic data as well as give you practical steps you can take to improve it. 

In this talk Rhonda Perciavalle Patrick, Ph.D. hits on vitamin D (an important hormone in brain function and dysfunction) as well as the MTHFR polymorphism (results in high homocysteine requiring supplementation with L methyfolate) which many Lyme patients have.  She also discusses limiting food intake as a method of affecting gene suppression in a positive way (calorie restriction & intermittent fasting).  She also discusses how using a sauna and exercise increases longevity. 

 Approx. 1 hour

Nutrigenomics, Epigenetics, and Stress Tolerance

Our genes influence the way we absorb and metabolize micronutrients. Nutrigenomics looks at the influence genetic variation has over micronutrient absorption/metabolism and the biological consequences of this dynamic relationship. Our diet also influences which of these genes are turned on or off! Emerging evidence in the field of epigenetics has demonstrated that not only can we change the expression of our own genes within our own lifetime; sometimes these changes are heritable and affect our children and grandchildren. This talk explores the intersection between genetics, nutrition, and environment: how your diet, micronutrients, exercise, heat stress, and sleep can change the expression of your genes and how this has profound effects on the way your body functions and ages.

For a brief explanation on Vitamin D by Rhonda:    Approx. 4:30
  • 30-80ng/ml the Sweet spot
  • Fish is a great source of D
  • Get your D levels tested regularly

Rhonda Perciavalle Patrick, Ph.D. is an assistant scientist at Children’s Hospital Oakland Research Institute and is a science communicator for a broad lay audience via her web and video presence found at FoundMyFitness.com.  It is Rhonda’s goal to challenge the status quo and encourage the wider public to think about health and longevity using a proactive, preventative approach.

Rhonda earned her Ph.D. in biomedical science from the University of Tennessee and performed her graduate research work at St. Jude Children’s Research Hospital. She also has a Bachelor’s of Science degree in biochemistry/chemistry from the University of California, San Diego. She has done extensive research on aging, cancer and nutrition, and metabolism.

________________

For more on MTHFR and methylation:

https://madisonarealymesupportgroup.com/2018/03/23/altered-dna-methylation-mental-illness-lyme-msids/

https://madisonarealymesupportgroup.com/2018/04/09/3-part-series-on-genetic-mutations/

https://madisonarealymesupportgroup.com/2018/08/01/methylation-what-you-need-to-know/

 

Toxic Metal Pollution Linked With Development of Autism Spectrum Disorder

https://m.medicalxpress.com/news/2018-09-toxic-metal-pollution-linked-autism.html

Toxic metal pollution linked with development of autism spectrum disorder

September 14, 2018 , RUDN University
Environmental metal and metalloid pollution (lead, mercury, aluminum, and arsenic) may induce autism spectrum disorders (ASDs) Credit: Vyacheslav Sheludkov

Russian researchers, together with their foreign colleagues, have demonstrated that environmental metal and metalloid pollution (lead, mercury, aluminum, and arsenic) may induce autism spectrum disorders (ASDs), and have considered possible mechanisms of exposure to these substances. The study may be useful for the prevention and therapy of ASD. The article is published in the journal Environmental Research.

Autism spectrum disorder is a group of disruptive neurodevelopmental disorders that cause problems in communication, socialization, and limited interests. They appear usually at the age of three years. Over the past 20 years, the prevalence of ASD has increased by 30 percent globally, although scientists have not yet reached a consensus on the causes and mechanisms of the disorder. Genetic mutations correspond to approximately 7 percent of cases of ASD. Such mutations can occur under the influence of in the first months of prenatal and postnatal life, when the nervous system is especially sensitive to toxic environmental pollutants. This hypothesis is confirmed by recent studies. For example, scientists from RUDN University with their colleagues from Saudi Arabia and Norway have observed increased lead and mercury levels in association with selenium deficiency in erythrocytes of children with ASD. A large Korean study including 458 mother-child pairs showed a clear link between exposure to mercury in early childhood and autistic behavior at the age of five.

But how, exactly, can toxic metals cause ASD? Researchers of the RUDN University and Yaroslavl State University, under the guidance of Prof. Anatoly Skalny, believe that the main mechanism underlying the onset of ASD is in brain . The latter is related to increased levels of pro-inflammatory cytokines—signaling peptide molecules. In addition, arsenic disrupts the metabolism of neurotransmitters and promotes epigenetic changes. Finally, aluminum can cause dysfunction of glia – non-neuronal auxiliary cells of the nervous tissue, which play an important role in the functioning of the nervous system. These assumptions are confirmed by the results of the authors’ studies, which demonstrated a tight association of the level of toxic elements in the blood serum of children with ADS and neuroinflammatory markers.

Researchers from the RUDN University considered the link between exposure to three toxic metals (lead, mercury, aluminum) and arsenic with the emergence of ASD in children. They proposed three main processes that occur under the influence of toxic metals and contribute to the development of autism: neuroiflammation, apoptosis (programmed cell death), and excitotoxicity. In addition, the scientists proposed preventive measures and approaches that reduce the risk of ASD.

“Unfortunately, the contemporary methods of metal detoxification do not allow to achieve ASD remission, especially since their effectiveness in ASD is not confirmed from the positions of evidence-based medicine,” noted the co-author of the article Alexey A. Tinkov, M.D., Ph.D., senior lecturer of the Department of Medical Elementology of the RUDN University.

In the case of acute intoxication, the use chelating agents (DMPS, DMSA, CaEDTA and BAL) is recommended, but in the case of ASD, chronic metal overload usually takes place. Moreover, chelators also have a significant number of side effects. In the case of chronic intoxication, toxic metals can be successfully eliminated from the body by functional foods. A number of phytochemicals (polyphenols, etc.) decrease lead toxicity. In turn, laboratory data demonstrate that zinc and selenium compounds significantly reduce toxicity of lead, arsenic and cadmium.

Researchers recommend the use of a comprehensive approach for the correction of metal overload in ADSs. Particularly, in addition to elimination of metals exposure, it is proposed to use antioxidants and anti-inflammatory compounds, as well as supplements containing heavy metal antagonists (selenium, zinc), and adhere to a diet.

More information: Geir Bjørklund et al. Toxic metal(loid)-based pollutants and their possible role in autism spectrum disorder, Environmental Research (2018). DOI: 10.1016/j.envres.2018.05.020

Provided by: RUDN University

**Comment**

A prominent Wisconsin Lyme doctor states 80% of his Autistic patients also have a Lyme/MSIDS infection.

For more on the metal issue:

https://madisonarealymesupportgroup.com/2017/09/19/autism-aluminum-adjuvant-link-corroborated/

https://madisonarealymesupportgroup.com/2018/06/15/canadian-data-more-autism-where-vaccine-coverage-is-highest/

https://madisonarealymesupportgroup.com/2018/06/01/immunoexcitotoxicity-as-the-central-mechanism-of-etiopathology-treatment-of-autism-spectrum-disorders-a-possible-role-of-fluoride-aluminum/

https://madisonarealymesupportgroup.com/2017/11/28/biological-mechanisms-of-vaccine-injury/

In depositions in a trial in Tennessee, scientists from the Kennedy Krieger Institute at Johns Hopkins University make it clear that children really should be screened before their first vaccination. If screening for individual susceptibility were done, many vulnerable children would be spared from being harmed by vaccines.”  https://articles.mercola.com/sites/articles/archive/2018/09/16/how-to-end-the-autism-epidemic.aspx?

For those who believe the CDC’s rhetoric that “vaccines do not cause Autism,” please see slide #5 of James Lyons Weiler’s work showing at least 12 studies showing an association:  vials-health-summit-slides-james-lyonsweiler-magic

The Russian study stated that genetic mutations are responsible for 7% of children with Autism. The study in this link https://madisonarealymesupportgroup.com/2017/10/26/clinical-trial-shows-most-kids-with-autism-are-not-born-with-it/ showed a similar finding that most children with Autism are NOT born with it:  Autologous Cord Blood Infusions Are Safe and Feasible in Young Children with Autism Spectrum Disorder: Results of a Single-Center Phase I Open-Label Trial  

https://madisonarealymesupportgroup.com/2018/09/05/pans-autism-the-immune-system-an-interview-with-expert-neurologist-dr-richard-frye/

 

 

 

 

 

 

Prebiotics & Probiotics: Do They Really Work For Gut Health?

https://vitalplan.com/blog/do-prebiotics-and-probiotics-really-work-for-gut-health?utm_campaign=September+15+VP+newsletter%3A+Pre%2Fprobiotic

Prebiotics-and-Probiotics-for-Gut-Health

Prebiotics + Probiotics: Do They Really Work for Gut Health?

by Beth Janes | Posted September 12, 2018

Prebiotics and probiotics have been trending for a while now, but lately they’re getting even more attention — and showing up in more and more products, from packaged foods (pizza crust!) to topical skin-care products. It’s no surprise consumers are interested: As scientists learn more about the trillions of bacteria that inhabit our bodies and the role they play in our health, some have touted beneficial bugs as a cure-all for digestive distress and other health problems.

But there are still many unknowns among researchers, and a lot of questions and confusion among the rest of us about what prebiotics and probiotics are, and what exactly they can and can’t do, says Bill Rawls, M.D., medical director of Vital Plan. Here, he answers some of the questions he hears most often.

What’s the difference between prebiotics and probiotics?

“Prebiotics are types of fiber, such as inulin, that are known to promote the growth of healthy microflora in the gut,” Dr. Rawls says. In other words, prebiotics feed the good bacteria already living in your gut, which allows them to multiply, thrive, and better do their job of keeping you healthy.

Probiotics, on the other hand, are actual strains of friendly bacteria or yeast that populate your gut. Ideally, probiotics maintain or restore a healthy balance of microflora, either by keeping bad bacteria in check or giving a hand to the good bacteria so they can function and flourish.

What are the best sources of both?

For prebiotics, the best sources are vegetables, hands down, Dr. Rawls says. Certain veggies such as sunchokes, mushrooms, garlic, artichokes, dandelion leaves, onions, and chicory contain high amounts of inulin, but you needn’t be overly selective.

More than anything else, eating a range of vegetables will cultivate the growth of normal bacteria,” Dr. Rawls says. “Because it’s not just about feeding the good bacteria: All vegetable fiber helps ensure normal digestion and that you’re evacuating the gut properly and regularly, which prevents the buildup of harmful bacteria.”

As for probiotics, fermented foods such as sauerkraut, kimchi, kombucha, kefir, and yogurt are naturally rich sources of live and active cultures (as well as digestive enzymes, which may be equally important for normal digestion). “Humans have eaten lots of different kinds of fermented foods throughout our history, for many thousands of years,” says Dr. Rawls. “That’s where the original idea for probiotic supplements came from.”

Research also suggests real-food sources of probiotics may be more effective than probiotic supplements at maintaining a diverse and healthy gut microbiome, the collection of microbes that inhabit your digestive tract. That could be due to the bacteria themselves, or the fact that the foods also contain a plethora of other healthy nutrients, including prebiotics, Dr. Rawls says.

Can prebiotics and probiotics improve digestive symptoms?

Prebiotics do contribute to a happy, symptom-free gut in the sense that they serve as fuel for the good microbes that help keep the digestive process humming. So while on their own they don’t do much, you absolutely need prebiotics for gut microbiome support and healthy digestion. Natural foods are by far the best source — supplements aren’t necessary if you’re eating a healthy, balanced, and veggie-rich diet.

As for probiotics’ ability to improve digestive symptoms, the answer is possibly. Probiotic capsules seem to help most when they’re used short-term for acute GI upset (diarrhea, stomach cramps) from eating contaminated food, like a batch of chicken salad that sat out for too long, for example, Dr. Rawls says. They may also help protect your microflora while taking antibiotics, which kill off good bacteria along with the bad, or if you contract C. difficile, a dangerous bacterial infection that causes diarrhea and inflammation of the gut.

“Most probiotic supplements contain bacterial strains of lactobacilli or bifidobacteria, or a favorable yeast called saccharomyces boulardii,” Dr. Rawls says. “Those are the ones that seem to show the most benefit.”

As for other digestive conditions, it’s hit or miss, he says. “The gut contains 20,000-plus strains of bacteria, and bacterial counts in the trillions. A probiotic supplement may be just a drop in the bucket, so getting an effect can be really hard.”

Further complicating things is that the mix of bacteria in people’s guts varies widely — in fact, it’s probably unique to you, like a fingerprint. What’s more, your microbiome can change based on your diet or lifestyle, or due to illness, so what might work for one person with a certain condition or symptom might not won’t work for another, Dr. Rawls says.

In addition, while different brands may use the same species of bacteria (lactobacillus, for example), they usually contain slightly different strains. So unless human studies on that one specific strain or bacteria blend shows a benefit on your particular health concern, it’s difficult to know for sure whether it will help you.

For all those reasons, published research is also mixed. Some is promising; for example, one meta-analysis of 15 studies published in the World Journal of Gastroenterology reported that probiotic supplements reduced pain and symptom severity in those with irritable bowel syndrome compared with placebo.

But other research, especially in healthy adults, shows little benefit from taking probiotics. And in fact, it may even introduce new symptoms: One small study of 30 subjects, published in the journal Clinical and Translational Gastroenterology, showed that taking a lot of probiotics can result in symptoms like brain fog and bloating in those using them for GI complaints.

Still, many experts tend to agree that the supplements, when taken in moderate doses, pose little risk. “I think it’s fine if someone wants to try taking probiotics; the potential for harm is low,” Dr. Rawls says. “Some people — maybe 15 to 20 percent of folks – may even gain benefit from them long-term.”

The newest trend in probiotics is customized formulations that are said to be based on your unique microbiome needs. Companies develop them after testing your stool sample for different microbes, and then selecting probiotics they say you lack in your gut. “While it may be a step in the right direction, the science and technology have a long way to go before this is a viable option,” says Dr. Rawls.

If you want to try supplements, he suggests taking them daily for at least three months and keeping a journal to see if you notice any improvements. If you won’t remember to take them daily, however, don’t even bother. Because the strains of bacteria in supplements are not the same ones already living in your gut, it takes a few days for them to populate and build up in your gut, and then you must continue to deliver them via supplements to maintain any activity.

What are some alternatives to probiotics for microbiome balance?

Step one is eating a mostly plant-based diet that includes plenty of fermented foods. Getting plenty of sleep and exercise and keeping stress in check are also key, as too little sleep and activity and too much angst contribute to overgrowth of bad bacteria.

Beyond that, Dr. Rawls says herbs and botanicals are more reliably effective and beneficial than probiotic supplements in the long-term. A few to key ones to reach for:

  • Chlorella, a type of green algae, is thought to be one of the most nutrient-dense foods available. It contains chlorella growth factor (CGF), a complex of proteins, vitamins, and sugars that works with fiber in the GI tract to promote the growth of healthy intestinal flora. It also contains chlorophyll, a potent antioxidant that binds to toxins and helps remove them from the body. “Chlorella is known for detoxification, but I’ve found that it does wonders for promoting normal GI function,” Dr. Rawls says.
  • Berberine, a compound found in several bitter herbs and other plants that’s well known for helping to balance the gut microflora. It’s been used for centuries to address intestinal disorders and digestive problems. “Berberine works very nicely because it stays predominantly in the GI tract, isn’t absorbed, and it’s active against gut pathogens,” Dr. Rawls says. That helps tip the scales toward healthy bacteria, keeping the bad guys from taking over.
  • Andrographis is likewise known to help support a healthy microbiome, plus it offers immune system-supporting capabilities. Native to India, andrographis can help promote good bacteria in the gut for better total balance, Dr. Rawls says.

The bottom line: Keeping your gut microbiome balanced is vital for maintaining healthy digestion, promoting sleep and immune strength, and more – and natural approaches are the best way to achieve that balance, says Dr. Rawls. Feel free to give probiotic supplements a try if you like, but be sure to track your progress to make sure it’s worth the money. And know that supplementing with the right herbs and botanicals, along with eating plenty of natural sources of both prebiotics and probiotics, will likely deliver the results you seek much more quickly.

_________________

**Comment**

My LLMD has noticed a stark contrast in patients from when before he started using probiotics in their treatment regimen and after.  He states it’s important to use a reputable lab and a refrigerated probiotic/prebiotic with many strains.  Refrigerated ones should be “live” cultures.

In all the years we’ve been in and out of treatment with antibiotics, we’ve never had GI issues and much of that is do to a low/no sugar diet and good pre and probiotics.

 

EBV & Chronic Fatigue Connection Podcast – Dr. Rawls

 Aug. 2018, Approx 1 hour 20 Min.

The Epstein Barr Virus + Chronic Fatigue Connection with Dr. Bill Rawls

In this webinar replay, Dr. Bill Rawls shares his insights about the mysterious Epstein-Barr virus (EBV) and its close connection with chronic fatigue syndrome (CFS).

For more:  https://madisonarealymesupportgroup.com/2018/08/18/free-webinar-epstein-barr-chronic-fatigue-connection-dr-rawls/  (Other links found here)

EBV is ONE of nine herpes viruses.  Behind Mono, it is spread by contact with saliva and is highly contagious.  It infects immune cells like the White blood cells, B cells, T cells, NK cells and epithelial cells (linings).  Nearly everyone is infected but most are asymptomatic.  It does respond to antiviral therapy.  In my experience some patients with tick borne illness get better after anti-viral therapy.

____________________

**Comment**

Many with Lyme/MSIDS also struggle with chronic fatigue and/or EBV. In fact, people have been misdiagnosed with both but had Lyme/MSIDS. For more on EBV:
https://madisonarealymesupportgroup.com/2017/11/04/24514/
https://madisonarealymesupportgroup.com/2017/04/11/diagnosed-with-ebv-had-lyme/
https://madisonarealymesupportgroup.com/2018/04/25/ebv-protein-can-turn-on-genes-for-autoimmune-diseases/

The Facts About Candida Overgrowth & How to Overcome It

https://www.wakingtimes.com/2018/06/28/the-facts-about-candida-overgrowth-and-how-to-overcome-it/

The Facts About Candida Overgrowth and How to Overcome It

June 28, 2018
candida overgrowth

Anna Hunt, Staff Writer
Waking Times

Candida is an essential fungus, a form of yeast, that lives in the human body. You can find it in the mouth and the intestines. Although it is normal to have some of this fungus in the body, candida can also invade the body beyond what is acceptable. This is called candida overgrowth, and it can have some detrimental health effects.

Candida Overgrowth

Having too much candida in the body can result in several health problems. This includes all types of digestive issues because too much candida can break down the walls of the intestines. In addition, candida overgrowth may cause problems such as depression, lack of energy, and a whole lot of annoying ailments.

When the production of candida in the body is out of control, it can manifest the following problems:

  • Allergies, sensitivities and intolerance to anything or any place that’s damp or moldy.
  • Hay fever and asthma.
  • Higher sensitivity to typical allergens, such as perfumes, smoke, odors, pets, dust, molds, pollen, and other airborne substances.
  • Athletes’ foot or fungus growth on other parts of the body.
  • Low body temperature, resulting on cold hands and feet.
  • Cold-like symptoms, including excessive mucus, as well as flu-like symptoms.
  • Digestive problems, such as constipation, abdominal bloating or pain, acid reflux, and gas.
  • Ringing in the ears (tinnitus), ear infections, ear aches, and abnormal wax build-up.
  • Fatigue, chronic fatigue and general feeling of being drained of energy.
  • Swollen salivary glands, dryness in the mouth, and swollen lymph nodes.
  • Dry or itchy scalp, dandruff, scalp sores, and hair loss.
  • Headaches, migraines, brain fog, and dizziness.
  • Fungal infections of the skin or nails.
  • Joint stiffness, swelling or pain.
  • Lack of appetite.
  • Nasal congestion, postnasal drip, sinus inflammation or infections.
  • Muscle aches and pains, including numbness and tingling, as well as lack of strength and coordination.
  • Dry skin, acne, hives, itching skin, and rashes, including eczema and psoriasis.
  • Sleep problems, such as frequent waking up and restless sleep, as well as insomnia.

FREE ONLINE EVENT: The Candida Summit – register today

The sad part is that candida overgrowth may be easily mistaken for other illnesses. Therefore, medical professionals often treat the symptoms of candida overgrowth, and not the actual problem of candida.

Why Does Candida Get Out of Control?

One of the biggest culprits in candida overgrowth are antibiotics. These medications wipe out all bacteria, including beneficial bacteria in the digestive system. On the other hand, antibiotics do not affect candida, because it is a fungus. As a result, taking antibiotics can create an imbalance in the body.

Now, if the immune system is strong, it can usually handle the effects of candida overgrowth. Unfortunately, many people have a weakened immune system because the typical western diet lacks the nutrients necessary to maintain strong immune function.

The standard diet consists of lots of carbohydrates, hydrogenated oils, trans-fats, sugar, white flour products, and processed foods. In addition, food growers often treat live foods with pesticides and herbicides. As well, they grow these foods in nutrient-depleted soil and radiate them to extend shelf-live.

Consequently, mainstream food choices do not give us the nutrients and healthy probiotic properties necessary to maintain a healthy immune system. As a result, when candida overgrowth happens, the body frequently starts to break down.

Some other factors that may contribute to candida population growing beyond what is healthy are:

  • A diet high in sugar and refined carbohydrates,
  • Drinking too much alcohol, and
  • A stressful lifestyle.

Simple Home Test

The best way to know for sure if you have candida overgrowth is to see a holistic practitioner. However, you can try the following test at home:

  1. Make sure you conduct this test first thing in the morning, before you eat or drink anything.
  2. Fill a glass with room-temperature, filtered water.
  3. Work up some saliva and spit it into the glass of water.
  4. Wait 30 minutes (you may need to wait up to 60 minutes) and check the saliva. If you see string traveling down into the water from the saliva, or if cloudy saliva has sunk to the bottom of the glass, you may have a candida problem.
What You Should Do to Help with Candida Overgrowth

There is a process that you can follow to control candida overgrowth. The important thing is that you execute the following five steps simultaneously:

1. Eliminate sugary foods that feed candida.

These include foods with sweeteners such as honey and fructose. In addition, you may want to limit the intake of fruits because they are high in sugar.

When buying processed meats, always read the ingredients because many contain sugar. In fact, read the ingredients list for all processed foods. You’ll be surprised just how many contain sweeteners. Of course, don’t forget that alcohol and many drinks, like a chai latte and coffee drinks, also have lots of sugar.

2. Strengthen your immune system.

This requires a healthy diet, high in lean proteins, good fats and low carbohydrates. All the foods you eat should be fresh and as natural as possible. This means limit processed foods so you eat fewer additives, heavy metals, pesticides and other food industry chemicals.

Another step in supporting a healthy immune system is to supplement with essential vitamins and minerals. The best way to understand what supplements you need is to ask your healthcare practitioner to administer a blood test. Some typical supplements that typically help fortify the immune system are:

  • Chlorella, a whole food that has many vitamins and minerals. It helps the body purge heavy metals and pesticides.
  • Vitamin C, one of the biggest immune system boosters. Since we get lots of Vitamin C from fruit, you are more likely to be Vitamin C deficient when limiting fruit intake to eliminate sugar from your diet. Vegetables rich in Vitamin C include kale, spinach, and broccoli.
  • Vitamin E, a powerful antioxidant that helps the body fight off infection. Foods rich in vitamin E include nuts, seeds and spinach.

3. Kill off candida overgrowth.

The most effective way to start getting rid of excess candida is to fortify your diet with anti-fungal foods. These include the following:

  • Raw garlic, which contains Sulfur compounds with anti-fungal properties. Fresh garlic is most potent, especially if you first crush it and wait about 10 minutes before consuming it. Of course, you can eat the garlic with a meal to conceal the taste. Just keep it raw.
  • Raw unfiltered apple cider vinegar, preferably Bragg brand. It is best to dilute 1 tablespoon of apple cider vinegar in a glass of room temperature water. Then, drink 30-60 minutes before a meal.
  • Olive leaf extract, which contains a phenolic compound with antiviral and anti-fungal properties.
  • Pau d’arco, which is sold as a tea or as a capsule supplement.

Remember that taking too many supplements can be a strain on the liver, so always check with your healthcare provider if you plan to take several supplements at one time. The ideal way to supplement is to eat a large variety of organic raw vegetables.

4. Introduce more good bacteria into the digestive system.

It is essential that you re-establish the balance of candida and good bacteria in your body. The best way to do this is by eating foods rich in probiotics, or “friendly” bacteria. These are also called probiotics.

Probiotics are present in foods such as yogurt, sauerkraut, kimchi and kombucha. The best way to get high quality probiotics into your system is to make fermented vegetables at home. Probiotic drinks are also very easy to make at home.

As well, you can buy probiotic supplements with a minimum of 50 billion CFUs (colony forming units). If possible, purchase probiotic supplements that require refrigeration.

5. Stay calm and expect the best results from your healing process.

When your body is already compromised, the last thing you need is stress. Stress on its own can make all the other previous four steps ineffective. In fact, it may have been a culprit in candida overgrowth in the first place.

It is important to utilize several stress relieving techniques during your healing process to help you stay calm. These include exercise, meditation and yoga. Also, don’t forget to have some fun!

Another important aspect of staying stress-free is to take it easy on yourself. Do your best following the steps above, and always be patient and kind to yourself.

Finally, having the right mindset is just as important as following a healthy diet. If you believe that your self-care efforts will pay off in improved health, then that will be your end result. There is a reason why the placebo effect works! The mind is one of the most powerful healing tools, so don’t forget to use it.

About the Author
Anna Hunt is writer, yoga instructor, mother of three, and lover of healthy food. She’s the founder of Awareness Junkie, an online community paving the way for better health and personal transformation. She’s also the co-editor at Waking Times, where she writes about optimal health and wellness. Anna spent 6 years in Costa Rica as a teacher of Hatha and therapeutic yoga. She now teaches at Asheville Yoga Center and is pursuing her Yoga Therapy certification. During her free time, you’ll find her on the mat or in the kitchen, creating new kid-friendly superfood recipes.

Sources: 

mindbodygreen.com
nourishedmagazine.com
thecandidadiet.com
preventdisease.com

This article (The Facts About Candida Overgrowth and How to Overcome It) was originally created and published by Waking Times and is published here under a Creative Commonslicense with attribution to Anna Hunt and WakingTimes.com. It may be re-posted freely with proper attribution, author bio, and this copyright statement.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of Waking Times or its staff.

Jen Springer, 2016

3 Reasons You Can’t Get Rid Of Candida Yeast : HCL, estrogen, thyroid.
  1. The first thing most people miss is restoring the pH to the proper level in the stomach. pH of 2-4. If you don’t get to that level your stomach doesn’t catalyze the pancreas to make enzymes, the gallbladder to make bile, and the proper growth of acid loving good bacteria: acidophilus. Betaine HCL is what you need before any other supplements. SIBO is caused by low stomach HCL. Low good bacteria is from low stomach HCL. The right pH needs to be first before anything else.
  2. Estrogen dominance / imbalance. Many people have estrogen higher than testosterone and progesterone. Even excess environmental estrogenic toxins. This causes high insulin and blood sugar levels. High blood sugar is YEAST FOOD!!! Yeast loves sugar. You be come a puffy loaf of bread.
  3. The thyroid!!! The candida likes to grow when the body is not operating at 98.6. When the body is low, like 97.5, the body can’t cook off the pathogens and keep them in check.
________________________________________
In my search for answers I found this:
This chiropractor resolved her candida with this treatment:
  • 1 drop clove essential oil mixed with olive or coconut oil in a capsule in the am and pm (so twice a day)  
  • Increase to a maximum dose of 6 drops of clove in oil per capsule twice a day
  • Use for 14 days then take a break for a week or two
  • It might take a few cycles to resolve
  • She noticed a “yeast dump” on day 8 of the first cycle
  • Clove oil is supposedly 75% more effective than Nystatin
  • Make sure you use reputable sources for all ingredients
Please work with your medical practitioner on all treatment suggestions.

For more:  https://madisonarealymesupportgroup.com/2018/08/02/can-these-essential-oils-help-lyme-patients-overcome-chronic-candida/

https://madisonarealymesupportgroup.com/2018/07/16/understanding-candida-overgrowth-natural-solutions-for-yeast-infection/

https://madisonarealymesupportgroup.com/2018/07/05/candid-signs-you-have-it-what-to-do-the-candida-summit-online-free-july-9-15-2018/

https://madisonarealymesupportgroup.com/2014/10/17/candida-the-chameleon/

 

 

The Cocktail Effect

The following article is a reminder that we must be ever diligent about what we put into and onto our bodies and I would add into our minds.  It’s also a reminder that we need to consider everything we are taking and understand the possible synergistic effects of those substances.  It’s common for patients to not be completely honest with their medical professionals about everything they are taking.  They will be open about all the pharmaceutical agents but they often are reticent to mention the so-called “natural” substances as they fear the potential negative reactions; however, this is a mistake from numerous standpoints – 1) trained professionals can only truly help if they know everything the patient is taking 2) “natural” substances have effects as well 3) the combination or synergy of everything we are taking might interact into what Dr. Brogan calls “The Cocktail Effect.”

Be honest with yourself and your practitioners.

Also, remember that people have vested interests and it’s often about sales not you.  Only you truly care about you.  Take the time to learn.  Ask your pharmacist questions.  Learn.  Never quit learning.  It won’t be wasted.

And lastly, if you’ve read anything I’ve ever written, it’s become clear that scientists and researchers have vested interests as well.  And these interests do not concern primarily you.  Their heads have been turned by the bombshells in the corner:  money & power.

https://kellybroganmd.com/the-cocktail-effect/?

The Cocktail Effect

Be skeptical.

Be very skeptical when you are delivered platitudes of reassurance about the safety of chemicals and pharmaceutical products from those who stand to profit from their sales. It can take more than a decade for signals of harm to trickle into consciousness.  We have an even more complex problem at play here: scientists are not doing the right types of studies.

I specialized, in residency and fellowship, in the “safety” of psychiatric medications during pregnancy and breastfeeding. After memorizing every study on the subject, I furrowed my brow and said, “Hold on a minute…these studies aren’t asking the right questions!” They ask – are babies born on time, are they big or small, and are they born with ten fingers and ten toes.

In today’s modern day toxic soup, these questions miss the mark of establishing the risk of chronic disease and neurodevelopmental delay and dysfunction. These studies tend not to control for important variables of biochemical individuality such as inflammatory markers, the gut microbiome, and obesity. And they definitely don’t ask questions about synergy.

What’s Synergy?

It’s the dynamic effects of toxicants in combination. It’s the new toxicology. One that acknowledges that even low doses of chemicals, particularly when combined, can sabotage cellular processes. It also acknowledges the role of hormones in this reaction, from cortisol to estrogen.

A powerful new study published in Nature Communications meets the science head on, exploring the Cocktail Effect. It looks at the effect of a synthetic estrogen in the birth control pill  on the toxicity of a pesticide. The endocrine disrupting potential of the more than 150,000 chemicals in our environment may have the capacity to disrupt our metabolism when combined with pharmaceutical exposures as common as oral contraceptives.

Delfosse et al are the first to identify how this can happen by showing that independent chemical molecules can help each other plug into the same hormonal receptor and activate it in a supercharged way. The amazing fact is that these chemicals have this hormonal effect at doses at which they are inactive when separate. In their non-user-friendly jargon, they state:

Our results suggest that the formation of ‘supramolecular ligands’ within the ligand-binding pocket of nuclear receptors contributes to the synergistic toxic effect of chemical mixtures, which may have broad implications for the fields of endocrine disruption, toxicology and chemical risk assessment.

What this means is that one chemical/toxicant can make you more vulnerable to another, as we have seen with glyphosate, the active ingredient in Roundup, and that multiple chemicals can wreak more havoc than individual chemicals alone.

Here’s one more reason to ditch birth control, go organic, and clean up your products!

_________________

**Comment**

Great, great reminder.  If you haven’t begun this life “clean up” process, take a deep breath and realize it took you decades to develop your habits.  It’s going to take some time to change them.  Please, don’t beat up on yourself now, just start.  Take one thing and then when you are able, take another thing.

I remember feeling so overwhelmed when I first found out both my husband and I were infected with numerous tick borne illnesses.  I knew we were at the precipice of something monumental and my mind went crazy with the implications – from how we were going to pay the monumental out-of-pocket medical bills, to the implications of homeschooling 3 teenagers (something we were already doing but now were ill & broke to boot), to the timing of the plethora of medications, to considering dietary, and other changes that needed to be made.  It seriously made me want to scream in frustration as I was having trouble remembering why I walked into a room!  The insomnia was maddening and I couldn’t handle stress at all.  The pain sent me to the fetal position in bed, and trying to unravel my husband’s hallucinations made me feel as if I stepped into a Sci-Fy novel of the worst kind – the kind where reality and fantasy are inseparable.

So just begin by putting one foot in front of the other.

 

 

 

 

 

 

 

Methylation – What You Need to Know

https://vitalplan.com/blog/methylation-what-you-need-to-know?

Methylation: What You Need to Know

by Dr. Bill Rawls | Posted June 9, 2018

Methylation-What-you-need-to-know
If you haven’t yet heard the term methylation, there’s a good chance you’ll soon start hearing it a lot more. Many people are beginning to clue into the importance of this biochemical process, which is a key component of overall wellness, and yet myths and misconceptions are more common than facts. Understanding methylation, and knowing how to optimize it, can give you an edge on staying healthy as you age.
So what is methylation? In biochemical terms, methylation is when a “methyl group” consisting of three hydrogen atoms and one carbon atom are linked to another molecule. Attaching a methyl group to an organic molecule (a chemical compound that contains carbon) makes it less reactive.
In more laymen terms, methylation is a process of making molecules more stable, which is important for a wide range of metabolic functions in the body. For starters, it balances hormone and neurotransmitter activity, and regulates protein synthesis and cellular energy. It processes DNA/RNA, the molecules that are responsible for storing and reading our genetic information, and repairs DNA. And it optimizes the functions of T-cells, white blood cells that play a key role in immune response.
Methylation also helps neutralize toxic substances: When methyl groups attach to organic toxins such as heavy metals, it reduces their toxicity and allows for easier removal from the body. When you consider that the modern world is loaded with higher concentrations of artificial toxins than ever before in history, maintaining optimal methylation is increasingly vital.
One of the most important roles of methylation is regulating the expression of genes. At any given time, you are using only about 1% of your genetic material; the rest of it is in “off” mode. But there are certain factors notorious for turning on “bad” genes that are associated with chronic illness, many of which are unique to the modern world. These include eating a poor diet high in processed food products, exposure to environmental toxicants, dealing with chronic stress, and having a sedentary lifestyle.
This is where methylation comes in — the way the body turns off “bad” genes is by attaching methyl groups to genetic material. Of course, if you don’t change your diet and lifestyle, the bad genes will turn on and/or stay on. Keep stressing your genes, and all the methyl groups in the world aren’t going to help you stay well.

The role of poor methylation in chronic illness

This is a huge misconception: People with symptoms of chronic illness — typical ones being fatigue, neurological symptoms, mood disorders like anxiety, and insomnia, to name a few — are being told that poor methylation is the cause of their illness. But in fact, it’s those same stressors that activate bad genes that increase susceptibility to illness; poor methylation just compounds the problem.

The Western diet is the biggest culprit. The body relies on a steady stream of methyl donors from certain foods to support the metabolic functions that are dependent on methylation. (Methyl donors are any substance that can transfer a methyl group — three hydrogen atoms and one carbon atom — to another substance.) It can use a variety of methyl donors, but the four most important components are methionine (an amino acid) and the B vitamins: methylfolate (B-9), B-12, and B-6.

Unfortunately, modern grain- and meat-based diets are very poor sources of methylfolate and other B vitamins. Food companies often try to compensate for the loss of natural folate by adding folic acid to their products, but it’s not an adequate substitute. What’s more, people who over-consume processed foods tend to develop gastrointestinal problems and lose the ability to produce a substance called intrinsic factor, which is essential for absorption of vitamin B-12.

Genetics also play a role in methylation proficiency. About 50% of the population carries a mutated gene (MTHFR) for an enzyme called 5-MTHF reductase. This gene is necessary to convert homocysteine (an amino acid most abundant in meat) into methionine, an amino acid that’s essential for the methylation process. About 40% of the population carries one MTHFR mutation, and 12% of the population carries a double mutation.

Having MTHFR mutations, however, may be less of a factor in chronic illness than some experts suggest. The evidence linking concerns such as myalgic encephalomyelitis/chronic fatigue syndrome, fibromyalgia, and Parkinson’s disease to the presence of a mutated 5-MTHF reductase gene is mild at best. Scientific investigations have shown only a very slight increased incidence of chronic illnesses in affected individuals.

That’s because this genetic pathway is only one of a variety methylation pathways. The human body would never rely on a single option for a function like methylation which is so essential for life. In addition, for most of history, humans consumed large amounts of plant matter that provided all the components necessary for methylation (methionine, B-9, B-12, and B-6). It’s only in recent history, as our diet has become more plant- and nutrient-deficient, that this particular genetic methylation pathway has become “essential.”

How to know when it’s time to test

People often ask which symptoms indicate they should get tested for poor methylation, but there are no pure telltale signs. My answer is, if you have classic symptoms of chronic illness such as fibromyalgia or ME/CFS, and you eat a lot of processed foods and very few vegetables, it’s pretty safe to assume have poor methylation.

The biggest reason to have the test is to determine whether you have a double mutation, in which case supplementation with natural folates may be valuable. Determining whether you have a MTHFR mutation requires a simple blood test that costs about $150.

Checking for elevations of homocysteine in your blood can tell you the degree of the problem: The higher your homocysteine levels, the lower the formation of methylfolate for making methionine, if methylation mutations are present. More than anything else, elevations of homocysteine indicate over-reliance on grains and meat as a food source.

6 ways to support proper methylation

Maintaining proper levels of methylation is important for health, but it must be part of a more comprehensive strategy. Again, nothing can balance the damage that comes from eating a nutrient-poor diet, living in a toxic environment, allowing stress to get the best of you, and sitting all day. Follow the simple steps below to help ensure optimal methylation, and whether or not you carry a MTHFR mutation will become a non-issue:

1. Eat your veggies.


Focus especially on dark green leafy vegetables such as spinach and kale, as well as asparagus, broccoli, cauliflower, and peas and beans (preferably sprouted). A healthy, plant-based diet containing these foods is the number one way to ensure you take in plenty of methylfolate, one of the primary methyl donors.

2. Get plenty of B vitamins.


Folate is a B vitamin, but vitamins B6 and B12 can be important methyl donors, too. You’ll find them in salmon, eggs, nuts and seeds, plus bananas, avocados, and soy.

3. Look for active forms of B-vitamin methyl donors.


If you take daily vitamin and mineral supplements to support your health, check ingredient lists to be sure they contain bioactive forms of the B vitamin methyl donors, which means they’re in a form your body can actually use. Here’s what they’ll look like on the label:

  • Folate (active forms: 5-Methyltetrahydrofolate or l-Methylfolate) Note that folic acid found in most multivitamin products is not satisfactory. It is not absorbed and utilized in the body properly, especially if you have a MTHFR mutation. This is particularly true if you are pregnant, in which case supplement with methylfolate, instead of folic acid, and consume plenty of leafy greens.
  • B6 (active form: Pyridoxal 5-Phosphate)
  • B12 (active forms: Methylcobalamin or Hydroxocobalamin)

4. Supplement with glutathione, if needed.


Glutathione is an essential antioxidant and another methyl donor, and it’s important for a myriad of processes in the body. Supplementing isn’t as necessary for young, healthy people, but chronic illness and aging put extra pressure on the body, so extra glutathione can be beneficial. Taking SAMe is another way to support the methylation process, but again, it’s unnecessary for young, healthy people, or if you’re getting adequate bioavailable B vitamins.

5. Consider restorative herbs.


Opt for herbs that support your immune system, microbiome and other functions such as andrographis, Japanese knotweed, milk thistle and sarsaparilla. “Any of the restorative herbs will help counteract a wide spectrum of stress factors in the body, and therefore help take pressure off of detoxification and healing systems,” Dr. Rawls says. “Cordyceps and reishi are also good examples, because they support immune system functions.”

6. Stay active, manage stress, and cut back on alcohol.


It’s common sense that living a healthy lifestyle helps keep everything in your body running smoothly. But research has started connecting the dots between lifestyle factors such as sedentary behavior, stress, and toxins such as alcohol with changes in DNA methylation.

Proper methylation impacts so many health systems of the body, and the simple steps outlined above can help support and enhance the process — MTHFR gene mutation or not. Enjoy your favorite produce, take steps to stay active and keep stress in check, and supplement with the right nutrients and herbs, and you’ll be paving a path toward a long, healthy, vibrant life.

References
1. Richardson, B. “DNA methylation and autoimmune disease.” Clinical Immunology 2003 Oct;109(1):72-9
2. de Vega, WC et. al. “DNA Methylation Modifications Associated with Chronic Fatigue Syndrome.” PLoS One 2014; 9(8): e104757.
3. Sokratous, M. et. al. “Deciphering the role of DNA methylation in multiple sclerosis: emerging issues.” Autoimmunity Highlights. December 2016, 7:12
4. Varela-Rey, M. et. al. “Alcohol, DNA methylation, and cancer.” Alcohol Research. 2013;35(1):25-35.
5. Phillips, T. “The Role of Methylation in Gene Expression.” Nature Education 1(1):116
6. Jones, MJ et. al. “DNA methylation and healthy human aging.” Aging Cell. (2015) 14, pp 924-932
7. Jones, Meaghan J. et. al. “DNA methylation and healthy human aging.” Aging Cell (2015) 14, pp 924-932
8. De Vocht, F. et al. “DNA methylation from birth to late adolescence and development of multiple-risk behaviours.” Journal of Affective Disorders. 2018 Feb; 227: 588–594.

________________

For more:  https://madisonarealymesupportgroup.com/2018/03/23/altered-dna-methylation-mental-illness-lyme-msids/

https://madisonarealymesupportgroup.com/2018/04/09/3-part-series-on-genetic-mutations/