Archive for the ‘research’ Category

How Are MS & Chronic Lyme Related?

Although this article is about MS, I wanted to post this information from Dr. Makis on fibromyalgia since both have many similar symptoms:  https://makismd.substack.com/p/ivermectin-and-fibromyalgia-testimonials?

In short, fibromyalgia patients are experiencing great relief, and even cure with ivermectin.  Many are stating their pain is entirely or nearly gone.  A few MS patients claim ivermectin cured their MS.

https://www.lymedisease.org/multiple-sclerosis-chronic-lyme/

How are multiple sclerosis and chronic Lyme related?

By Bill Rawls, MD

April 21, 2025

Multiple sclerosis (MS) is a disease where the immune system attacks the protective covering (called myelin) around nerves in the brain and spinal cord.

Myelin acts like an insulator to keep nerves from touching each other and shorting out, much like the plastic coating on a copper wire.

This damage disrupts nerve signals, leading to symptoms such as fatigue, muscle weakness, numbness, vision problems, and coordination difficulties.

Undoubtedly, plenty of people who identify as having chronic Lyme disease struggle with these same symptoms. And demyelination of nerves has been documented for Lyme disease. Beyond that, many people with MS test positive for Borrelia, the Lyme bacteria. So what distinguishes MS from chronic Lyme?

The answer: arbitrary cut-offs.

So how do we differentiate?

There is no single test that is specific for MS. The diagnosis of MS is made using a combination of clinical evaluation, imaging, such as MRI, and laboratory tests of blood and spinal fluid.

If all of the findings are deemed significant enough by the clinician evaluating the patient, then the diagnosis of MS is made and the patient qualifies for treatment.

This means that a person could have all of the symptoms, and some or all of the findings, but not to the degree that would qualify for a diagnosis of MS.

That person might end up being diagnosed with some other neurological condition, fibromyalgia, or maybe wouldn’t get a diagnosis at all. Chronic Lyme disease is unlikely because it isn’t a diagnosis recognized by the conventional medical community.

No diagnosis, no treatment. But maybe that’s not such a bad thing.

Getting to the root cause

There are numerous drugs for treatment of MS. They work by blocking inflammation or blocking the immune system’s assault on myelin. The benefits are marginal at best and they carry significant side effects.

What the drugs don’t do is address why the body is attacking myelin in the first place. Without getting to the root causes of the problem, patients typically don’t get well. They live in a compromised state of relying on medications to mask the symptoms of their illness.

When you start looking for underlying causes, you’ll find that MS is listed as multifactorial. In other words, it’s not one specific cause, but rather multiple variable causes. This is also true of other chronic illnesses, including chronic Lyme disease.

A review paper published in the 2023 edition of the journal, NeuroSci, cataloged some of the known risk factors for MS that may be causative. These risk factors can be grouped into five categories.

  • Diets rich in processed foods and saturated fat, but low in vegetables and fruit
  • Chronic mental stress with inadequate sleep
  • Smoking or chronic exposure to other toxic substances
  • Sedentary lifestyle
  • Certain myelin-scavenging microbes, including (but not limited to) Chlamydia pneumoniae, Epstein-Barr Virus (EBV), Human Herpesvirus-6 (HHV-6), Mycoplasma pneumoniae and other mycoplasma species, and Borrelia burgdorferi

While the review didn’t go as far as defining how these factors might come together to cause MS, it doesn’t take much imagination to figure out a possible scenario.

A plausible explanation for MS

Myelin is contained within specialized cells called oligodendrocytes, which wrap around the shaft of a nerve to insulate it. Each of these microbes are known to invade oligodendrocytes to scavenge myelin as a resource for replication. While this provides one possible link to MS, that’s not the end of the story.

Evidence shows that the microbes can go dormant inside an oligodendrocyte after they invade it. Intracellular dormancy is a common survival mechanism used by many host-dependent microbes. It has been documented for borrelia and all the Lyme coinfections. Dormancy allows microbes to survive when conditions aren’t favorable for growth — in other words, when the cells they’ve invaded are healthy.

When cells are weakened by chronic stress factors — poor diet, chronic exposure to toxic substances, unrelenting mental stress and poor sleep, being sedentary — dormant microbes are able to reactivate, consume the cell, and then emerge to infect adjacent cells.

The immune system reacts by attacking the oligodendrocytes where microbes are emerging, in the process compounding the damage.

This is also a plausible explanation for chronic Lyme disease. The question remains: Why do some people progress to more advanced symptoms that are ultimately defined as MS?

The answer may be genetics. A variety of genetic mutations are common among people diagnosed with MS. You can’t do anything about genetic mutations, of course, but you can do something about the root causes of the problem.

A natural solution for MS and chronic Lyme

One obvious part of the solution is minimizing stress factors that weaken cells. Not surprisingly, there are many documented cases of people who went into stable remission from MS after modifying their health habits.

Improved health habits alone, however, don’t completely address the microbe factor. Fortunately, there is one thing that does — and it’s not antibiotics or other drugs.

Certain medicinal herbs demonstrate antimicrobial and immunomodulating properties that offer the potential for an ideal solution to support recovery from MS. They are already used widely for chronic Lyme disease and supported by sound evidence.

Among numerous studies, a study from Johns Hopkins University showed that certain herbs — cryptolepis, Japanese knotweed, and Chinese skullcap — were more effective for killing Borrelia than antibiotics.

Unlike an antibiotic, however, which is a single chemical agent specific for only certain microbes, an herb contains hundreds of chemical substances that act as a chemical defense system against a wide range of microbes, including bacteria, viruses, protozoa, and yeasts.

Never just one

This is important because it’s never just one microbe possibility. People identifying as having chronic Lyme disease typically test positive for co-infections. Chronic Lyme co-infections associated with demyelination include Chlamydia pneumoniae, Epstein-Barr Virus (EBV), Human Herpesvirus-6 (HHV-6), Mycoplasma pneumoniae and other mycoplasma species.

But these are just the ones that have been identified so far — there are probably many others.

Combining multiple herbs extends the range of coverage. This is possible because the potential for toxicity of the most commonly used herbs in Lyme protocols is inherently low.

Medicinal herbs and mushrooms that are commonly included in chronic Lyme protocols that could also be beneficial for MS recovery include:

  • Japanese knotweed (Polygonum cuspidatum)
  • Cat’s claw (Uncaria tomentosa)
  • Chinese skullcap (Scutellaria baicalensis).
  • Cryptolepis (Cryptolepis sanguinolenta)
  • Andrographis (Andrographis paniculata)
  • Reishi (Ganoderma lucidum)
  • Cordyceps (Cordyceps sinensis)
  • Berberine or berberine-containing herbs
  • Red sage (Salvia miltiorrhiza)
  • Rehmannia (Rehmannia glutinosa)

Very importantly, the complex chemistry of herbs and medicinal mushrooms also protects cells from a wide range of toxic threats, including free radicals, foreign toxic substances, and harmful radiation. This applies to all cells in the body, including cells that make up the nervous system.

Immunomodulators

The medicinal herbs and mushrooms listed are classified as immunomodulators, meaning they upregulate underactive parts of the immune system and downregulate overactive portions of the immune system. This is important for reducing inflammation and calming the autoimmune response.

A final advantage of antimicrobial herbs is specificity for pathogens. The antimicrobial properties of herbs and medicinal mushrooms are selective for pathogens, but do not disrupt normal flora in the gut and other areas of the body.

Low toxicity and low potential to disrupt the gut microbiome means that herbal therapy can be used for extended durations, months or even years, which is often what it takes for complete recovery.

What this all means is that therapy — with a targeted endpoint of wellness, not managed illness — can be started with or without having a formal diagnosis.

With over 30 years of medical experience, Dr. Bill Rawls specializes in the holistic treatment of chronic illnesses, particularly Lyme disease. His personal journey with Lyme disease inspired his mission to empower others with the knowledge and tools needed to regain their health naturally. Learn more about Dr. Rawls’ approach to treating chronic illness with herbal therapy at RawlsMD.com.

References

An X, Bao Q, Di S, et al. The interaction between the gut microbiota and herbal medicines. Biomed Pharmacother. 2019;118:109252.

Anderson C, Brissette CA. The Brilliance of Borrelia: Mechanisms of Host Immune Evasion by Lyme Disease-Causing Spirochetes. Pathogens. 2021;10(3):281.

Berer K, Mues M, Koutrolos M, et al. Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination. Nature. 2011;479(7374):538-541.

Bjornevik K, Münz C, Cohen JI, Ascherio A. Epstein-Barr virus as a leading cause of multiple sclerosis: mechanisms and implications. Nat Rev Neurol. 2023;19(3):160-171.

Branton WG, Lu JQ, Surette MG, et al. Brain microbiota disruption within inflammatory demyelinating lesions in multiple sclerosis. Sci Rep. 2016;6:37344.

Eisenreich W, Rudel T, Heesemann J, Goebel W. Persistence of Intracellular Bacterial Pathogens-With a Focus on the Metabolic Perspective. Front Cell Infect Microbiol.

Feng J, Leone J, Schweig S, Zhang Y. Evaluation of Natural and Botanical Medicines for Activity Against Growing and Non-growing Forms of B. burgdorferi. Front Med (Lausanne). 2020;7:6.

Fritzsche M. Chronic Lyme borreliosis at the root of multiple sclerosis–is a cure with antibiotics attainable? Med Hypotheses. 2005;64(3):438-448.

Greening C, Grinter R, Chiri E. Uncovering the Metabolic Strategies of the Dormant Microbial Majority: towards Integrative Approaches. mSystems. 2019;4(3):e00107-19.

Ivanova MV, Kolkova NI, Morgunova EY, et al. Role of Chlamydia in multiple sclerosis. Bull Exp Biol Med. 2015;159(5):646-648.

Kriesel JD, et al. Spectrum of Microbial Sequences and a Bacterial Cell Wall Antigen in Primary Demyelination Brain Specimens Obtained from Living Patients. Sci Rep. 2019 Feb 4;9(1):1387.

Landry RL, Embers ME. The Probable Infectious Origin of Multiple Sclerosis. NeuroSci. 2023;4(3):211-234.

Libbey JE, Cusick MF, Fujinami RS. Role of pathogens in multiple sclerosis. Int Rev Immunol. 2014;33(4):266-283.

Livengood JA, Gilmore RD Jr. Invasion of human neuronal and glial cells by an infectious strain of Borrelia burgdorferi [published correction appears in Microbes Infect. 2015 Jun;17(6):e1]. Microbes Infect. 2006;8(14-15):2832-2840.

Pender M. The essential role of Epstein-Barr virus in the pathogenesis of multiple sclerosis. Neuroscientist. 2011;17(4):351-367.

Rittershaus ES, Baek SH, Sassetti CM. The normalcy of dormancy: common themes in microbial quiescence. Cell Host Microbe. 2013;13(6):643-651.

Thakur A, Mikkelsen H, Jungersen G. Intracellular Pathogens: Host Immunity and Microbial Persistence Strategies. J Immunol Res. 2019;2019:1356540.

Toledo A, Benach JL. Hijacking and Use of Host Lipids by Intracellular Pathogens. Microbiol Spectr. 2015;3(6):10.1128/microbiolspec.VMBF-0001-2014.

_______________

**Comment**

A few points:

  • The Johns Hopkins study was in vitro, or the lab, which may not transfer over to the human body.
  • Antibiotics of daptomycin, doxycycline, and cefuroxime were used as controls at a final concentration of 5 μg/ml.  I’m not sure how this translates to oral dosages given patients, but according to Burrascano, dosages matter greatly.  It could be that these dosages were not high enough.
  • Doxy is a great front-line drug due to its action against many coinfections, but it is not the best and only drug to treat Lyme disease.
    • Eva Sapi found that while the use of doxy reduced spirochetal structures ~90%, round body forms increased about twofold.What this means is these round forms will simply lie and wait until conditions are better to reemerge. She found that tinidazole was the only antibiotic that reduced viable organisms by ~90%.  Recent research showed piperacillin effectively cured mice of Lyme at a dose 100 times smaller than doxycycline with virtually no impact on resident gut microbes.
So, for anyone paying attention, doxy has its limitations and all experienced Lyme literate doctors use multiple antibiotics in a combination therapy.

This, right here, is why mainstream medicine and research are worthless because this complex illness is treated as a one pathogen, one drug illness when typically more than one pathogen involved, and to complicate it further, the pathogens have multiple forms (pleomorphism) and strains that need to be addressed.

  • Daptomycin is an antibiotic that has been utilized recently in combination therapies. In a study through Johns Hopkins, when combined with doxycycline and ceftriaxone, daptomycin effectively cleared Lyme disease infection in vitro as well as in mice. However, daptomycin is relatively expensive and only available intravenously.  Notice it’s effectiveness is due to being used in a combo therapy.  I would say this is true of ALL antibiotics and why single antibiotics were not successful in the Johns Hopkins study Rawls refers to.
  • While cefuroxime has been found to have a minimum bactericidal concentration (MBC) similar to doxycycline; out of three borrelia species tested, two were susceptible while the third (borrelia hermsii) was less susceptible. The three antibiotics with similar MBCs in vitro, i.e., cefuroxime, doxycycline, and amoxicillin, demonstrated comparable activities in preventing borreliosis in B. burgdorferi-challenged hamsters (50% curative doses = 28.6, 36.5 and 45.0 mg/kg, respectively). So cefuroxime is far from perfect either when used alone.  Source

Using single antibiotics is really doing an injustice to what is known about successful treatment for Lyme since tindy is the most effective drug overall and combination drug protocols are by far the most effective.

Please remember too that Dr. Rawls manufactures and sells herbs and is financially compensated.

Don’t misunderstand – I’m not opposed to herbs.  I’ve used many myself and know of patients who have done well on them.  I just don’t want you to believe they are perfect or the only answer, either.  It takes everything AND the kitchen sink for this crap so keep an open mind.  And herbs are not harmless – there are interactions with other drugs as well as toxicity.

Nothing is ever simple.

For more:

Category:

Herbs, Lyme, research, Treatment

Why Doctor Treated Patient for Lyme – Even When His Test Was Negative

https://danielcameronmd.com/treated-lyme-negative-test/

Why I Treated Him for Lyme—Even When His Test Was Negative

Posted By: Dr. Daniel Cameron
May 13, 2025

Patients Deserve an Explanation

One of the most common—and most important—questions I hear from patients is:
“If my Lyme test is negative, why are you still treating me?”

It’s a fair question. And if you’re asking it, you deserve a clear and compassionate answer. The truth is, when it comes to Lyme disease, test results don’t always tell the full story.

Let’s break down why.

Lyme Disease Testing Isn’t Always Reliable

The standard test used to diagnose Lyme disease is called the two-tier system. It includes an ELISA screening test followed by a Western blot if the first result is positive. But this system is far from perfect—especially when the infection is in its early or late stages.

Here’s what you should know:

  • Early in the infection, your body may not have produced enough antibodies yet to trigger a positive result
  • Some patients never produce detectable antibodies at all
  • Co-infections like Babesia or Bartonella are not picked up by this test
  • Many rashes don’t appear in the textbook “bulls-eye” pattern—or don’t appear at all
So yes—you can absolutely have Lyme disease, even if your test is negative. And unfortunately, this is more common than many realize.

In Medicine, We Don’t Wait for Disease to Get Worse

In most areas of healthcare, we don’t wait for a serious event before we start treatment.

  • We don’t wait for a stroke to treat high blood pressure
  • We don’t wait for vision loss to manage diabetes
  • We don’t wait for full organ failure to address chronic kidney disease

We act early—because we know that early treatment improves outcomes. So why does Lyme disease often get treated differently?

When it comes to Lyme, many patients are told to “wait and see”—even when the symptoms are clear and distressing.

Waiting Is Not a Neutral Decision

Here’s what I tell my patients:
Waiting is not harmless. It’s a medical decision with consequences.

Delaying treatment can allow symptoms to worsen. It can allow the infection to persist or spread. In some cases, patients who were told to wait eventually end up with a label: Post-Treatment Lyme Disease Syndrome (PTLDS)—a condition where symptoms linger long after the initial infection was treated, or in some cases, never properly treated at all.

What if we had treated earlier? Could we have prevented months—or even years—of suffering?

In many cases, the answer is yes.

Clinical Judgment Is Not Guesswork

When I decide to treat someone for Lyme disease despite a negative test, it’s not a random decision. It’s based on:

• The full pattern of your symptoms

• Your medical history

• Your response to prior treatments

• Known or likely tick exposure

• And experience with thousands of Lyme patients

This is called clinical judgment. It’s a core part of good medical practice. I don’t ignore science—I apply it in context. Because Lyme doesn’t always follow the rules, and neither should we when those rules are failing real people.

You Know When Something Feels Wrong

I’ve met patients who’ve been told their symptoms are “just stress” or “hormonal” or “all in their head.” But they know their bodies. They’ve tracked their fatigue, their joint pain, their cognitive changes. They’ve seen something shift—and they’re right to speak up about it.

Many of those patients improve once treatment begins, even if their test results never confirmed the diagnosis. That’s not luck. That’s Lyme disease showing up in real life—even when it doesn’t show up in the lab.

It’s Time to Rethink How We Treat Lyme

We’re in a new era of medicine. Patients are more informed, more proactive, and more in tune with their own health than ever before. But too often, our Lyme diagnostic standards are stuck in the past—waiting for certainty while people lose months or years of their lives to untreated illness.

We need to bring clinical judgment back into focus. We need to listen more, wait less, and treat Lyme disease with the urgency it deserves.

Final Thoughts

If you’ve been told your test is negative, but you’re still struggling with symptoms—please know this:
You’re not imagining it. You’re not overreacting. And you’re not alone.

In my practice, I treat the whole patient—not just the lab result. Because when it comes to Lyme, early treatment can change everything.

Want to learn more? Follow my blog series for more insights on Lyme disease diagnosis and care—or reach out to my office if you’re looking for answers.
You deserve to be heard.

Related Articles:

Relying on a negative Lyme disease test can prove deadly

Don’t wait for a positive Lyme disease test

Can’t trust single dose of doxycycline to prevent Lyme disease

_______________

**Comment**

A very needed article with crucial information for all to understand.

Testing for Lyme/MSIDS is abysmal.  Clinical judgement is required; however, doctors receive little training for tick-borne infections and whatever training they do receive is antiquated and biased.  The fact the needle hasn’t budged in 40 years is proof of this fact.

Dr. Cameron is an example of an independent doctor who could save your life.  He’s also a Lyme-literate doctor who has studied under ILADS and who has years of experience treating this.  Like many of his colleagues, he’s been attacked by the state medical board – which is common for these doctors because they do not partake in the globalist idea for ‘consensus-based’ medicine – which turns doctors into robots who blindly follow dictates from bureaucrats who are profiting from conflicts of interests including patents, drugs, and other metabolomics. 

Due to the horrific lack of education on all things Lyme/MSIDS, there is a parallel group to the tyrannical IDSA (Infectious Diseases Society of America) called ILADS (International Lyme and Associated Diseases Society) which holds their own medical conferences to educate doctors on what is happening in reality with Lyme/MSIDS and through independent, global research that the IDSA simply ignores or maligns. Their next conference, “The Complexity of Lyme: Diagnosing and Treating Tick-Borne and Related Diseases,” is June 7-8 in Philadelphia.

Our conference will include:

  • Introduction to diagnosing and treating vector-borne diseases
  • Case discussions with experts
  • Advanced topics in clinical treatments such as PANS/PANDAS, Mold toxicity, MCAS, supportive natural therapies and more.
  • Exhibitors showcasing medical services
  • CME credit available

The conference is open to healthcare professionals. Students enrolled in a medical degree program and PhD candidates conducting Lyme-related research are also eligible to attend and qualify for discounted rates. Email conference@ilads.org for more information.

Category:

Lyme, research, Testing, Treatment

Tuttle Destroys NASEM’s Lyme Disease Report

https://www.change.org/p/the-us-senate-calling-for-a-congressional-investigation-of-the-cdc-idsa-and-aldf/

The IDSA’s Post Treatment Lyme Disease Syndrome was not good enough!

Carl Tuttle
Hudson, NH, United States
May 15, 2025

The IDSA’s Post Treatment Lyme Disease Syndrome was not good enough so now we have yet another distraction avoiding the elephant in the room (chronic Lyme) called Lyme IACI; “Lyme Infection-Associated Chronic Illness.”

That should add another decade to the denial of chronic Lyme allowing the pharmaceutical industrial complex to roll out its Lyme vaccine and payouts in the form of patent royalties to all those responsible for this crime against humanity. It was that rush to create a vaccine early in the discovery phase of the epidemic that led to the deliberate mishandling of the disease. All the eggs were put into the vaccine basket before a cure was researched and uncovered. We have been dealing with an antibiotic resistant/tolerant superbug but the vaccine money grab was far too lucrative to pass up. Covid proved to us all that our Public Health Officials will do or say anything for the sake of a vaccine; “Safe and Effective“??????

Please take a moment to read the following inquiry sent to Marcia McNutt, President of the National Academy of Sciences regarding a recent publication referencing the latest acronym “Lyme IACI.”

Image of McNutt was found here: https://www.nasonline.org/directory-entry/marcia-mcnutt-6apamq/

Inquiry to Marcia McNutt:

———- Original Message ———-

From: CARL TUTTLE <runagain@comcast.net>
To: “mmcnutt@nas.edu” <mmcnutt@nas.edu>, “vdzau@nas.edu” <vdzau@nas.edu>
Cc: “wkearney@nas.edu” <wkearney@nas.edu>, “dmay@nas.edu” <dmay@nas.edu>, “amacdonald@nas.edu” <amacdonald@nas.edu>
Date: 05/14/2025 8:50 AM EDT
Subject: The National Academies Press; Charting a Path Toward New Treatments for Lyme Infection-Associated Chronic Illness

The National Academies Press

Charting a Path Toward New Treatments for Lyme Infection-Associated Chronic Illness (“Lyme IACI”)
https://nap.nationalacademies.org/read/28578/chapter/1

Marcia McNutt

President of the National Academy of Sciences and Chair of the National Research Council

“Most of my current activity centers around meta science – how to shape the culture and conduct of science to build trust, excellence, inclusiveness, and integrity.” – Marcia McNutt

Dear Marcia McNutt,

After reading through your Biosketch you seem to have the capability to detect scientific fraud. Would suppressing evidence of antibiotic resistance (for the sake of a vaccine) constitute a crime? Please take a moment to read the following inquiry addressed to Grace E. Marx, MD Medical Epidemiologist, Centers for Disease Control and Prevention. If the scientific references/evidence I provide were not suppressed the focus would have been on finding effective antimicrobials to treat this antibiotic resistant/tolerant superbug.

Question: Has the National Academy of Sciences under your direction just had the wool pulled over their eyes?

A response to this inquiry is requested.

Carl Tuttle
Independent Researcher
Hudson, NH

Cc: Victor J. Dzau President, National Academy of Medicine

William Kearney Executive Director of the Office of News and Public Information

David May Director, National Academies Press

Alphonse MacDonald Publisher, National Academies Press

Inquiry to: Grace E. Marx, MD Medical Epidemiologist, Centers for Disease Control and Prevention

———- Original Message ———-

From: CARL TUTTLE <runagain@comcast.net>
To: “grace.marx@cuanschutz.edu” <grace.marx@cuanschutz.edu>, “gmarx@cdc.gov” <gmarx@cdc.gov>
Cc: “katrina.rouse@usdoj.gov” <katrina.rouse@usdoj.gov>, “jonathan.kanter@usdoj.gov” <jonathan.kanter@usdoj.gov>
Date: 10/25/2024 9:11 AM EDT

Subject: Tick-Borne Diseases and Associated Illnesses, Community Engagement Series: Mental Health and Neurological Effects

Tick-Borne Diseases and Associated Illnesses, Community Engagement Series: Mental Health and Neurological Effects
https://www.hhs.gov/oidp/initiatives/tick-borne-diseases-associated-illnesses-national-community-engagement-initiative/index.html

3:00 pm – 3:20 pm   A Clinician Toolkit: Improving Care for Patients with Prolonged Symptoms and Concerns about Lyme Disease By Grace E. Marx, MD Medical Epidemiologist, Centers for Disease Control and Prevention

Dear Dr. Marx,

I listened to your presentation yesterday with great interest and I must congratulate you for your outstanding performance in suppressing all evidence of persistent infection; chronic Lyme disease.

We have studies proving persistent infection after antibiotic treatment for mice, dogs, ponies,  monkeys, cows, iris biopsy, and ligamentous tissue but if you perform a simple Google search for the following statement, “There is no convincing scientific evidence that chronic Lyme exists” you will find the top search results are connected to “elements of academic medicine” involved in the denial of the late stage Lyme epidemic.

In 1991 the Lyme disease organism, Borrelia burgdorferi, was grown from the cerebrospinal fluid of Lyme patient Vicki Logan at the Centers for Disease Control in Fort Collins, Colorado despite prior treatment with intravenous antibiotics. The patient died when the insurer refused additional IV antibiotics. Here is a copy of Logan’s CDC positive culture report for your review.

(Vicky Logan’s Chronic Lyme Autopsy results Page #1, 2, 3, 4, 5, 6, 7)

There are 700 peer-reviewed publications referencing persistent infection and in a 2018 study all patients were culture positive even after multiple years on antibiotics so there was no relief from current antimicrobials. Some of these patients had taken as many as eleven different types of antibiotics.

Thirty-four years ago Dr. Allen Steere identified chronic Lyme disease which should have set off a red flag prompting an immediate search for better antimicrobials but then did a 180° as he became principal investigator (PI) of the Phase 3 clinical trial for the first Lyme disease vaccine. So all the eggs were put into the vaccine basket while a campaign was orchestrated to discredit the sick and disabled patient population along with the courageous clinicians attempting to help these patients. Apparently, a chronic relapsing seronegative disease did not fit the business model of patent royalties, vaccine development and pharmaceutical profits.

Here is Dr. Steere’s 1990 publication summary for your review:

The New England Journal of Medicine 

Published November 22, 1990

Chronic neurologic manifestations of Lyme disease
https://www.nejm.org/doi/full/10.1056/NEJM199011223232102

The chart below summarizes Lyme research funded by the NIH and only 2.5% has been allocated for treatment:

[Click on the link above to view the chart]

For the record there are many infections requiring long-term antibiotics so why Klempner stopped his NIH funded antibiotic treatment trials for Lyme after 90 days makes absolutely no sense whatsoever:

From the following publication:

Benefit of intravenous antibiotic therapy in patients referred for treatment of neurologic Lyme disease
https://www.dovepress.com/benefit-of-intravenous-antibiotic-therapy-in-patients-referred-for-tre-peer-reviewed-fulltext-article-IJGM

Infections requiring long-term antibiotics:

[Download the article and View Table 4 as there are nine infections listed] 

Lyme misdiagnosed/undiagnosed for months, years or decades is far more incapacitating than “acute” Lyme and 2-4 weeks of antibiotics does not scratch the surface of this well-established/immune suppressive infection. These are the patients who need help the most but have been excluded in research for decades. There are countless stories of patients seroconverting after the initial few doses of Doxycycline and now that a toxin has been identified that puts Lyme disease in an altogether different category of infection:

Toxins 

Published: 21 May 2024

Borrelia burgdorferi 0755, a Novel Cytotoxin with Unknown Function in Lyme Disease
https://www.mdpi.com/2072-6651/16/6/233

So it would appear that one way to get a medical association (AMA) to go along with the suppression of evidence is to throw them a boatload of money… five million taxpayer dollars to be exact for a so-called IDSA biased “Clinician Toolkit”  (CDC grant number  NU50CK000597)

This controlling of the narrative has caused unimaginable pain and suffering all across America as insurance companies refuse to pay for long-term treatment, personal bankruptcies from out-of-pocket expenses to treat chronic infection, suicides from despair all while Valneva Received FDA Fast Track Designation for its Lyme Disease Vaccine.

Chronic Lyme must be recognized and finally addressed with 100% attention to effective antimicrobials for all stages of disease.

Question:

Is collusion to control the narrative through suppression of the truth, facts and scientific references a criminal offense?

Carl Tuttle
Hudson, NH

Cc: Assistant Attorney General Jonathan Kanter, Attorney Katrina Rouse

Attorneys for the United States Antitrust Division

Assistant Attorney General Jonathan Kanter Announces Task Force on Health Care Monopolies and Collusion
https://www.justice.gov/opa/pr/assistant-attorney-general-jonathan-kanter-announces-task-force-health-care-monopolies-and

“Every year, Americans spend trillions of dollars on health care, money that is increasingly being gobbled up by a small number of payers, providers and dominant intermediaries that have consolidated their way to power in communities across the country,” said Assistant Attorney General Jonathan Kanter of the Justice Department’s Antitrust Division. “Led by Katrina Rouse, the task force will identify and root out monopolies and collusive practices that increase costs, decrease quality and create single points of failure in the health care industry.”

2nd email sent to Marcia McNutt:

———- Original Message ———-
From: CARL TUTTLE <runagain@comcast.net>
To: “mmcnutt@nas.edu” <mmcnutt@nas.edu>, “vdzau@nas.edu” <vdzau@nas.edu>
Cc: “wkearney@nas.edu” <wkearney@nas.edu>, “dmay@nas.edu” <dmay@nas.edu>, “amacdonald@nas.edu” <amacdonald@nas.edu>
Date: 05/15/2025 9:14 AM EDT
Subject: Re: The National Academies Press; Charting a Path Toward New Treatments for Lyme Infection-Associated Chronic Illness

Dear Marcia McNutt,

Please see the inquiry below addressed to Dr. Raymond Dattwyler …..

Dr. Raymond Dattwyler owns 24 patents for Lyme disease that include diagnostic testing and vaccines both live bacteria and oral. Raymond Dattwyler, Benjamin Luft, et al have some interesting comments in their application for a Lyme related patent… 

Dattwyler et al. United States Patent 7,605,248 October 20, 2009
https://www.dropbox.com/scl/fi/1yxcrwjfhhw4q47999dug/Raymond-Dattwyler-Grant-2R01AI37256-05A1-from-the-National-Institute-of-Allergy-and-Infectious-Diseases..docx

“Currently, Lyme Disease is treated with a range of antibiotics, e.g., tetracyclines, penicillin and cephalosporins. However, such treatment is not always successful in clearing the infection. Treatment is often delayed due to improper diagnosis with the deleterious effect that the infection proceeds to a chronic condition, where treatment with antibiotics is often not useful. One of the factors contributing to delayed treatment is the lack of effective diagnostic tools.”

2022 Inquiry to Dr. Raymond Dattwyler: 

———- Original Message ———-
From: CARL TUTTLE <runagain@comcast.net>To: Raymond_Dattwyler@nymc.eduCc: npjvaccines@nature.com, abarrett@utmb.edu, R.W.Titball@exeter.ac.uk, mgomesso@uthsc.eduDate: 01/06/2023 2:46 PM EST
Subject: The year that shaped the outcome of the OspA vaccine for human Lyme disease

npj Vaccines Jan 2022

The year that shaped the outcome of the OspA vaccine for human Lyme disease
https://www.nature.com/articles/s41541-022-00429-5
Raymond J. Dattwyler & Maria Gomes-Solecki

Department of Microbiology and Immunology
New York Medical College
Valhalla, NY
Raymond J. Dattwyler, Corresponding Author

Dear Dr. Dattwyler,

I read your manuscript with great interest as you call attention to a treatment-resistant Lyme arthritis with “no evidence of DNA” found in the joints of patients after antibiotic treatment.

For some strange reason however, I could not find the following 1995 publication within your paper identifying treatment-resistant neuroborreliosis: 

European Neurology 1995

Seronegative Chronic Relapsing Neuroborreliosis
https://www.karger.com/Article/Abstract/117104
Lawrence C., Lipton R.B., Lowy F.D., Coyle P.K.d

Abstract

We report an unusual patient with evidence of Borrelia burgdorferi infection who experienced repeated neurologic relapses despite aggressive antibiotic therapy. Each course of therapy was associated with a Jarisch-Herxheimer-like reaction. Although the patient never had detectable free antibodies to B. burgdorferi in serum or spinal fluid, the CSF was positive on multiple occasions for complexed anti-B. burgdorferi antibodies, B. burgdorferi nucleic acids and free antigen. 

In fact, Dr. Dattwyler there seems to be a great deal of “treatment-resistant” evidence published in multiple journals over the past three decades:

Peer Reviewed Evidence of Persistence of Lyme Disease Spirochete Borrelia burgdorferi and Tick-Borne Diseases (700 References)
https://www.dropbox.com/s/n09sk90eo6xz7ua/700%20articles%20LYME%20EvidenceofPersistence-V2.pdf?dl=0

So that brings me to the reason for this email…

Question:

Does a chronic relapsing seronegative disease fit the vaccine model? If not, would that, in and of itself, be the hidden reason for denying chronic (treatment-resistant) Lyme disease for almost three decades? In other words, patent royalties and pharmaceutical profits over lifesaving care?

A response to this inquiry is requested.

Carl Tuttle
Hudson, NH

Cc: Alan D.T. Barrett, PhD Editor-in-Chief
Rick Titball, PhD, DSc, Deputy Editor

Letter to the Editor of the BMJ published June 2020
https://www.bmj.com/content/369/bmj.m1041/rr-1

_______________

**Comment**

Once again, kudos and a big ‘thank you’ go out to Lyme advocate Carl Tuttle for being a junk yard dog that refuses to let go of the jugular vein.

Tuttle has been tireless in writing letters and exposing Oz behind the Lyme curtain: repeated denial and cover-up of chronic, relapsing Lyme disease.

I posted the ‘new treatments for Lyme Infection-Associated Chronic Illnesses’ here:   https://madisonarealymesupportgroup.com/2025/05/09/charting-a-path-towards-new-treatments-for-chronic-lyme-disease/

I had a sinking feeling then that this would amount to nothing but further entrenchment in the old, antiquated and unscientific Lyme narrative.  It appears I was correct.  I included the old 2014 interview with Willy Burgdorfer, which I repost here, where he states research must be started over at square one because the same people have been doing the research and coming up with the same results – nothing!

http://  Approx. 5 Min

Willy Burgdorfer 2014

“Money goes to people that have for the past 30 years produced the same thing.  Nothing.” ~  Willy Burgdorfer

Well, it’s now been a total of more than 40 years and the same thing is being produced, which is nothing.

For more:

Category:

Activism, Lyme, research

‘Must Hear’ Dr. Hatfill Interview

http://  Approx. 1 Hour

Dr. Steven Hatfill Blows Whistle on COVID Treatments, Gene Therapy Injections, and Research Fraud

“They lied!”

Podcast by Dana Parish

May, 2025

This is one of the most shocking interviews I’ve ever done. Dr. Steven Hatfill, renowned virologist, bioweapons expert, author, and senior scientific adviser to HHS, joins me to reveal the debacle behind COVID, the ‘vaccine,’ early treatments, and what really happened behind the scenes during the pandemic.

Hatfill was wrongfully accused of the anthrax attacks in the early 2000s and later exonerated, earning a multi-million dollar settlement from the US Government. But that didn’t stop him from stepping back into the fire. During the first Trump administration, he became a fierce advocate for early COVID treatment while the mainstream medical establishment tried to silence him.

In this episode, he lays out the evidence on how COVID was bioengineered, early treatments were suppressed, the vaccines were entirely misrepresented, and much more.

_____________

**Comment**

No, you are not losing your mind.  I’ve posted this podcast before here:  https://madisonarealymesupportgroup.com/2025/05/14/study-confirms-covid-shots-laced-with-cancer-causing-dna/

I just felt it important enough to repost as some might have missed it.

And you don’t want to miss this one.

Dr. Hatfill answers all of Parish’s questions humbly and honestly.  I’m happy to report that everything posted on this website on the COVID chapter aligns with what Dr. Hatfill says in this interview.  I am indebted to doctors and researchers who shared prolifically on Linkedin early on.  Many of these experts are retired or not employed by the government and could speak freely.  Unfortunately, one by one, Linked in kicked these truth-tellers off the platform until one day I too was ‘disappeared.’  

Shame on platforms for censoring experts sharing information that could have saved lives.

The entire COVID chapter was mishandled from the start and there’s many people and organizations who need to be brought to justice over the fraud, deceit, and damage done in virtually every area.

And now, the IPAK-EDU White Paper 2025-ENDEUA states that when corrected efficacy curves and suppressed risks are taken into account, the mRNA covid shots fail the EUA standard.  The shots were based upon interim data from large-scale Phase III trials. The legal standard under §564 of the Federal Food, Drug, and Cosmetic Act requires that a product may be authorized for emergency use only if it is “reasonable to believe” that the product “may be effective” against a life-threatening condition, that the known and potential benefits outweigh the known and potential risks, and that no adequate alternatives are available. This report demonstrates, through a rigorous retrospective analysis, that these criteria were never met.

Trust me when I say, you need to hear this interview.  Please also share this widely, particularly to those who are still in the dark or need to hear it from an ‘expert.’  Hatfill knows his stuff.

For articles on the many topics Hatfill covers:

COVID is lab made:

Suppression of early, successful treatment:

How spike protein behaves in the body:

Is the shot gene therapy?  YES

Why was mRNA the government choice for COVID?

    • There are 9,613 patents licensed to giants in biotech and the US government
    • BARDA and DARPA have had a torrid love affair with mRNA for decades
    • A retrospective cohort study found the US government invested at least $31.9B to develop, produce, and purchase mRNA covid-19 shots, including sizable investments in the three decades before the pandemic through March 2022. 
    • While the study claims “millions of lives were saved,” the truth is the experimental, COVID gene therapy injections saved ZERO lives.

Links between COVID shots & Cancer

Nasal sprays to prevent COVID:

Persecution of doctors & health professionals who defied the global narrative:

Category:

Activism, research, Treatment, vaccines, Viruses

German Study Confirms COVID Shots Laced With Cancer-Causing DNA & Japanese Study Demonstrates Regulatory Failure: Autopsy-Proof ‘Vaccine’ Deaths Clearly Being Systemically Ignored

https://slaynews.com/news/major-investigation-confirms-covid-vaccines-laced-cancer-causing-dna/

Major Investigation Confirms Covid ‘Vaccines’ Laced with Cancer-Causing DNA

Frank Bergman

A major investigation by a group of renowned German researchers has confirmed that Pfizer’s Covid mRNA “vaccines” are laced with dangerous levels of DNA contaminants.

While the presence of DNA contamination in Covid injections is not a new discovery, this latest study uses advanced techniques for more reliable quantification, making it the most significant investigation to date.

As Slay News has previously reported, leading scientists have been warning for some time that surges in deadly cancers among the Covid-vaccinated were caused by DNA fragments in the mRNA injections.

The study was led by Jürgen O. Kirchner, an Independent Researcher in Hamburg, and Professor Brigitte König of the University of Leipzig.

The results of the study were published in the Preprints journal.  (See link for article)

_____________

Important excerpt:

The researchers confirm that their findings reveal that DNA contaminations exceeded safe levels by approximately 300 to 500 times.

Kevin McKernan, a former director of the Human Genome Project, described the findings as a “bombshell.”

“Chronic activation of the cGAS-STING pathway could paradoxically fuel cancer growth,” McKernan warned.

“Repeated exposure to foreign DNA through COVID-19 boosters may amplify this risk over time, creating conditions conducive to cancer development.”

While the authors concluded that these fragments were “non-replication-competent” meaning they cannot replicate in humans, McKernan disagreed.

“To assert that the DNA fragments are non-functional, they would need to transfect mammalian cells and perform sequencing, which wasn’t done here,” McKernan stated.

“Moreover, the methods used in this study don’t effectively capture the full length of DNA fragments,” he added.

“We’re in the stage where we’re scanning through tumors to look for integration events and looking for evidence of this in cancer biopsies,” McKernan said.

“And we can find them now.

“They found one that had really high spike [protein] sent to us for sequencing.

“And we can find components of Pfizer’s vaccines inside this thing a year after vaccination.”

_______________

Dr. Steven Hatfill, senior medical advisor at HHS, just gave an explosive interview with Dana Parish.  You will recognize Parish’s name as she’s a patient which has done numerous podcasts with Lyme literate doctor Steven Phillips.

Hatfill is a virologist and biodefense expert, serving as a special advisor in the Administration for Strategic Preparedness and Response (ASPR) under HHS Secretary Robert F. Kennedy Jr. since early this month. He also worked in the first Trump administration who has seen the cover-ups firsthand, and he’s calling out the mRNA vaccines for what they are: a dangerous experiment.

The interview focuses on the mRNA shots causing cancer.  You can tell Parish is having a hard time accepting that the ‘vaccine,’ vs the virus, is what is behind the explosion in cancer as it is my understanding she took the jab herself as many well-known Lyme literate doctors unfortunately promoted the hastily made experimental gene therapy injections.  (I could be wrong on this but I feel I read it somewhere) She also is a proponent of ‘Long COVID’ despite the unfortunate truth that the shot itself is most probably behind a majority of these cases.  While she wants to be non-polarizing, it’s imperative that each ‘long covid’ case is monitored for ‘vaccine’ involvement to properly determine causality.  Thankfully, she is reporting on the devastating effects of the shots now.

https://worldcouncilforhealth.substack.com/p/sensational-new-study-demands-urgent?

Sensational New Study Demands Urgent Re-evaluation of mRNA Vaccines

Immunodeficiency, excess deaths, and Japan’s dangerous replicon experiment.

May 14, 2025

A groundbreaking commentary published in Discover Medicine has exposed critical flaws in global vaccination programs, particularly concerning mRNA COVID-19 vaccines and their long-term immunological consequences. The peer-reviewed, open-access study (Yamamoto, 2025) highlights alarming trends:

  • Vaccine-induced immunodeficiency is linked to repeated mRNA dosing
  • Japan is the only country still aggressively promoting boosters—including self-amplifying RNA (replicon) vaccines
  • Excess deaths now surpass 600,000 in Japan post-vaccination, with no clear explanation beyond aging demographics
  • Three infant deaths within 24 hours of routine vaccination have been dismissed as “unable to evaluate” by regulators

Here’s what you need to know about Yamamoto’s findings and their urgent implications for public health policy.

Key points
1. mRNA vaccines cause immune dysfunction

Yamamoto notes research showing three key ways that mRNA vaccines screw up immune systems:

  • IgG4 antibody class switching. Repeated mRNA vaccination shifts immune responses toward non-inflammatory IgG4 antibodies, potentially blunting protection against infections (Irrgang et al., 2023).
  • Lymphocyte depletion. Studies report post-vaccination lymphopenia (Seban et al., 2022), raising concerns about temporary immunosuppression.
  • Vaccine-Acquired Immunodeficiency Syndrome (VAIDS). Some researchers warn that frequent boosters may erode natural immunity (Seneff et al., 2022).
2. Japan is taking more risks on this genetic tech than other nations

While most nations halted mRNA boosters by mid-2022 due to safety concerns, Japan continues administering 8th doses, including:

  • Self-amplifying mRNA (saRNA) vaccines—untested in humans until now.
  • Simultaneous administration with flu shots, obscuring adverse event causality.
  • Regulatory capture: vaccine review committees include pharma-funded members, while autopsy-confirmed deaths post-vaccination are routinely classified as “unable to evaluate” (γ).
3. Baby deaths and injuries are going unacknowledged

Yamamoto notes that three infants died within 24 hours of routine vaccinations.

While autopsies were performed, no causal link was officially acknowledged. This is symptomatic of a wider systemic failure to acknowledge vaccine harms. Japan’s compensation system has historically recognized 150+ vaccine-related deaths—but none from COVID-19 vaccines, despite 932 reported fatalities.

4. Japan’s excess mortality and hidden data

Some interesting observations from Yamamoto here:

  • The 600,000+ excess deaths in Japan since 2021 cannot be explained by COVID-19 alone.
  • Similar trends have been observed in highly vaccinated Western nations (Mostert et al., 2024).
  • Japan’s Ministry of Health (MHLW) misclassified vaccinated individuals as “unvaccinated” in early statistics, skewing efficacy data.

______________

**Comment**

Despite this information and a plethora of research now showing how dangerous the ineffective shots are, the new leadership supposedly in charge of MAHA (Make America Healthy Again) flip flop more than a waffle maker. The FDA will meet on May 22, 2025 to discuss and make recommendations on the selection of the 2025-2026 formula for COVID gene therapy injections for use in the U.S.

It appears that Podcaster Shannon Joy is completely correct: RFK & Trump is a ‘Deal With the Devil That Betrayed Medical Freedom.’

http:// Approx. 9 Min

MAHA FDA Chief, Marty Makary, Flip-Flops on COVID Shots

The Jimmy Dore Show

May 11, 2025

Newly minted FDA Chief Marty Makary is sending what some would consider “mixed” signals about his support for COVID boosters and mRNA technology. During a recent TV interview Makary said he wasn’t sure whether young, healthy children should be receiving booster shots. Whereas Makary has up to this point been among the most vocal critics of the COVID vaccine. Jimmy and former HUD Assistant Director Catherine Austin Fitts discuss why Makary would be changing his tune this way and whether he has been absorbed into “the box” that co-opts anti-establishment voices once they become insiders.

Even HHS Secretary Robert F. Kennedy recently supported the measles vaccine after an outbreak in Texas, despite saying in the past that US has measles outbreaks ‘every year,’ and that there are safety concerns about the live measles vaccine, saying testing was inadequate. He also raised safety concerns about the vaccine for pertussis. Just today Stanford scientists confirm a fatal case of vaccine-associated measles encephalitis in an immunocompromised child.

In this case, the vaccine measles virus hypermutated to a fatal strain that invaded the brain and killed the child.

If the child was unvaccinated, the AML would have been treated in the usual fashion, with a good chance at survival. Source

You won’t hear about this little factoid from mainstream media.

It will be interesting to see if the new FDA head of biologics, vaccines division, Dr. Vinay Prasad, waffles back and forth as well, as he was a vocal critic of all things COVID.

Sadly, much of the world will never come to grips with the COVID psyop that according to one expert had policy that is ‘completely stupid’ & unethical.’

Despite the MAHA rhetoric, until its leaders come clean, much of the public will remain shrouded in the dark, led by emotions rather than truth, and completely vulnerable to it all happening over and over.

Category:

Activism, Cancer, research, vaccines