Archive for the ‘Treatment’ Category

Chronic Lyme Disease Patients Want to Be Treated, Not “Managed” By Physicians

https://danielcameronmd.com/recommendations-to-clinicians-on-how-to-handle-chronic-lyme-disease-patients/

CHRONIC LYME DISEASE PATIENTS WANT TO BE TREATED, NOT ‘MANAGED’ BY PHYSICIANS

Over the past month, a series of articles, focusing on multiple aspects of Lyme disease, from pediatric Lyme to chronic Lyme to life after Lyme, have been published in the May and June issues of Infectious Disease Clinics of North America and Clinical Infectious Diseases. The articles echo messages that, for the most part, minimize a disease that impacts hundreds of thousands of people each year — many of whom are children.

“Minds are like parachutes. They only function when open.” This particular quote by Thomas Dewar came to mind after reading an article, Chronic Lyme Disease (1) in the June issue of Infectious Disease Clinics of North America.

In it, the author writes, “the scientific community has largely rejected chronic, treatment-refractory Borrelia burgdorferi infection.” This is based on “the failure to detect cultivatable, clinically relevant organisms after standard treatment.”

The intention of the Chronic Lyme Disease article is evident — convince readers that chronic Lyme disease does not exist, and that antibiotics prescribed for more than 14- to 28-days are of no benefit and most patients have no lingering symptoms.

It is particularly troublesome that the author, Paul Lantos, MD, a Duke University Medical Center researcher, is co-chair on a panel responsible for updating the Infectious Disease Society of America’s (IDSA) treatment guidelines for Lyme disease. Dr. Lantos holds a position not to be taken lightly. The IDSA recommendations will determine, for the most part, the types of treatment patients diagnosed with Lyme disease will receive.

Additionally, Dr. Lantos includes a section entitled, “Clinical Approach to Patients with Chronic Lyme Disease Diagnosis,” in which he offers suggestions to physicians on how to ‘manage’ patients complaining they have chronic Lyme disease. Recommendations include listening patiently during the consultation and then explaining to the patient why their symptoms are not related to Lyme disease.

“…a certain amount of time must be spent reviewing past experiences and past laboratory tests … then explaining why Lyme disease may not account for their illnesses.”

“Even if chronic Lyme disease lacks biological legitimacy, its importance as a phenomenon can be monumental to the individual patient,” says Lantos. “Many have undergone frustrating, expensive, and ultimately fruitless medical evaluations. And many have become quite disaffected with a medical system that has failed to provide answers.”

Managing patients, who insist they have chronic Lyme disease can be challenging, he warns. This subset of patients can have “great variation in their ‘commitment’ to a chronic Lyme disease diagnosis. Some patients are entirely convinced they have chronic Lyme disease, they request specific types of therapy, and they are not interested in adjudicating the chronic Lyme disease diagnosis.”

Should a clinician have a patient who believes they have chronic Lyme disease, there are several ways to manage the evaluation, he explains. First, “the physician needs to suppress preconceptions or biases about such patients.”

Second, “the process of clinical information gathering in medicine … is no different in the context of chronic Lyme disease. Even if much discussion is centered on chronic Lyme disease.”

And, lastly, “it is of utmost importance to not seem to be impatient, dismissive, or rushed. Many patients who seek care for chronic Lyme disease already have accumulated frustration. … Each patient’s clinical story and personal history is unique and valid, even if one concludes that they do not have Lyme disease.”

For the patients who do remain chronically symptomatic, Dr. Lantos explains, there has been “little evidence of active infection, and their symptoms do not respond to antibiotics any better than to placebo.”

When dealing with complex, chronic illnesses, physicians need to develop a trusting and understanding relationship with their patients. It is impossible for a clinician to provide the highest level of care to their patients, which includes a thorough evaluation, if they enter into the doctor-patient relationship with preconceived notions, not only about an extremely complex disease but about the patient who is reporting the symptoms, which are often subjective.

Should the patient not have any of the three objective signs of Lyme disease — the bulls-eye rash, swollen knee and/or Bell’s Palsy, identifying the infection is dependent on a strong evaluation. Patients want physicians to provide effective treatments. They don’t want to be ‘managed.’

It is time for a new narrative. One that recognizes the complexity of the Lyme spirochete and acknowledges the ineffective simplicity of the ‘one-size fits all’ treatment approach.

References:

  1. Lantos PM. Chronic Lyme Disease. Infect Dis Clin North Am, 29(2), 325-340 (2015).

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**Comment**

Lantos is obviously unaware of this which showed a 70% complete remission of symptoms:   https://madisonarealymesupportgroup.com/2023/07/24/paralyzed-by-lyme-they-were-helped-with-combo-treatments/

Also, it’s imperative to point out that coinfections are rarely taken into consideration, yet chronically infected patients are notoriously coinfected with other pathogens.  The fact they don’t improve is most probably due to the fact they are not treating these coinfections which can be as bad if not worse than Lyme.  Bartonella and Babesia are two such pathogens that can knock you off your feet but require very different medications than Lyme meds.  This is simply never discussed.

My husband and I are two chronically infected patients that have improved vastly with extended antimicrobial treatment.  Without this treatment, I’m not sure either of us would be alive.  I know many others in this boat as well.  We don’t make the research papers because none of us fit the criteria to even enter a study:

These parameters that continue to be used will continue to give a preconceived outcome: no chronic/persistent infection.  It’s circular reasoning of the worst kind that hasn’t budged in over 40 years.

Compare this to Dr. Lee Merritt’s informative talk where she describes experiments done on prisoners in the 1900’s that would see them deliberately infected with the Spanish Flu.

The experiments would see some of the prisoners injected with infected lung tissue from sick or deceased patients, have infected tissue dropped in their eyes, and sprayed in the nose and mouth with infectious aerosols. Others would see mucus taken from critically ill patients and put it into the noses and throats of prisoners. In other parts of the trials, experimenters would take the blood of the sick and inject it into the healthy, to see if it was spread through infectious microorganisms in the blood.

As well as the various fluid exchanges mentioned above, a further part of the experiments saw ten healthy prisoners taken into a hospital for patients who were dying of the disease. There, they were asked to stand over the sick and dying, lean over their faces and breathe in heavily while they exhaled. Just to be sure of exposure, the flu patients would cough into the face and mouths of the prisoners.

Ponder this for a moment.  
I mean, what is the likelihood?
Yet, despite this fact, we are told that the Spanish Flu is the most deadly virus on the planet.
According to many experts, this lack of proof of viral infectivity is a big deal but has resulted in a massively lucrative “vaccination” program that only worsens with time – now forcing people to concede to these injections or lose their jobs.
Meanwhile, back in Lymeland, lack of definitive proof stops the show.  Experts claim, “If we can’t see it, smell it, touch it, it doesn’t exist.” 
Anyone with half a brain would see this comparison and acknowledge that something is truly rotten in Denmark.

******

Genetics & Susceptibility to COVID

**UPDATE**

All of this was written about back in March when it was discovered that China has been purchasing the DNA of Americans. China’s BGI – a large manufacturer of one of the most popular prenatal tests in the world developed with the military, has been harvesting data from millions of women, and analyzing the data with AI.  So far 8 million women have taken BGI’s prenatal tests globally. One BGI study used a military supercomputer to re-analyze data and map the prevalence of viruses in Chinese women, look for indicators of mental illness in them, and single out Tibetan and Uyghur minorities to find links between their genes and their characteristics.

But wait, there’s more.
  • 60 Minutes learned that BGI offered to build COVID testing labs in at least six states and Chinese companies are investing in biotech companies which gives them access to health data.
  • Reuters reported that BGI, partnering with the PLA, share a dozen patents for DNA tests and one 2015 patent is for a “low-cost kit to detect respiratory pathogens, including SARS (Sever Respiratory Syndrome) and coronaviruses
  • BGI’s chief infectious disease expert is listed as an inventor on the patent while also being one of the 1st scientists to have sequenced COVID-19 samples from a Wuhan military hospital.
  • BGI, worth a market value of around $9 million and known for creating a cloned pig, has sold millions of their COVID-19 test kits around the world.
This should frighten everyone, but particularly immunocompromised Lyme/MSIDS patients as many of them get genetic testing done to try and help them fine-tune their treatment.

In April, 2021 this website posted an article showing that a relationship between the Gates Foundation and BGI goes back nearly a decade, with the Gates Foundation actually funding BGI projects relating to genome sequencing. The former president of the Bill & Melinda Gates Foundation’s global health program, serves as the Chairman of BGI’s Scientific Advisory Board.

One American genetic testing company widely used by Lyme/MSIDS patients called 23andme announced it would become a publicly traded company with the help of billionaire Richard Branson. A spider-web exists which includes Branson, Jeffrey Epstein, Bill Gates and the BGI Group.  Another little known web includes the CEO of 23andMe, her sister who is CEO of Youtube, and her former husband – one of the founders of Google (which owns Youtube) and president of Alphabet Inc. until 2019.

And frighteningly, work done by UW researchers here in Wisconsin could also be used for nefarious reasons.

In the video, UW researchers who in 2004 figured out how to safely and effectively get therapeutic DNA inside cells were mentioned.  But a Colonel in the People’s Liberation Army states:

University of Wisconsin scientists have made exogenous naked DNA and injected it into the veins for easy access into muscle cells for gene therapy.  By combining this knowledge and particle-gun technology, we could create a micro bullet out of a 1 micron tungsten or gold ion, on whose surface plasmid DNA or naked DNA could be precipitated, and deliver the bullet via a gunpowder explosion, electron transmission, or a high-pressured gas to penetrate the body surface. We could then release DNA molecules to integrate with the host’s cells through blood circulation and cause disease or injury by controlling genes.

While China amasses genetic information from around the world, it has banned the collection or preservation of its citizen’s genetic information.

All of a sudden, the following article does not seem so far fetched and makes a lot of sense.

https://thevaccinereaction.org/2023/07/genetics-may-predispose-susceptibility-to-covid/

Genetics May Predispose Susceptibility to COVID

It is generally accepted that COVID-19 (coronavirus disease 2019) is caused by an infection with the virus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). The virus enters human cells via a protein coding gene known as ACE2 (angiotensin converting enzyme 2). It is also largely accepted that COVID can affect different people in different ways, ranging from asymptomatic infection to severe disease, which can include respiratory failure and death. Some studies note, “risk factors for severe COVID-19 include male sex, older age, ethnicity, obesity and cardiovascular and respiratory diseases, among others.”1 2 3 4

Additionally, genetic factors have been shown to play a role in a person’s susceptibility to infection with SARS-CoV-2 and to developing severe symptoms of COVID.

Studies Suggest Genetic Factors Determine Reactions to COVID

Numerous studies have been undertaken to try and understand how host genetic factors can predispose someone to COVID. One study, for example, published in the journal Biochemistry and Biophysics Reports in December 2020 investigated how different “coding variants” of ACE2 among certain populations decreased or increased the SARS-CoV-2/ACE2 “electrostatic attention” or “binding energy.”2 5 6 

The authors stated:

Here, we combined ACE2 coding variants’ analysis in different populations and computational chemistry calculations to probe the effects on SARS-CoV-2/ACE2 interaction. ACE2-K26R; which is most frequent in Ashkenazi Jewish population decreased the SARS-CoV-2/ACE2 electrostatic attraction. On the contrary, ACE2-I468V, R219C, K341R, D206G, G211R increased the electrostatic attraction; ordered by binding strength from weakest to strongest. The aforementioned variants are most frequent in East Asian, South Asian, African and African American, European, European and South Asian populations, respectively.6

In another study published in the journal BMC Medicine in July 2020, researchers investigated genetic susceptibility to COVID by examining DNA polymorphisms (two or more variant forms) in ACE2 and the gene TMPRSS2 (transmembrane protease, serine 2). They identified 63 “potentially deleterious” variants in ACE2 and 68 “deleterious” variants in TMPRSS2, and they found that the “distribution of deleterious variants in ACE2” differs among nine populations. The researchers wrote:

Specifically, 39% (24/61) and 54% (33/61) of deleterious variants in ACE2 occur in African/African-American (AFR) and Non-Finnish European (EUR) populations, respectively Prevalence of deleterious variants among Latino/Admixed American (AMR), East Asian (EAS), Finnish (FIN), and South Asian (SAS) populations is 2–10%, while Amish (AI) and Ashkenazi Jewish (ASJ) populations do not appear to carry such variants in ACE2 coding regions.7

There are many other similar studies that indicate that genetic factors within different geographic and ethnic groups can play a role in the susceptibility of these populations to SARS-CoV-2 infection and the manifestation of COVID symptoms. This may explain why COVID has affected certain people disproportionately.8 9 10

Biology Can Also Determine Reactions to Other Diseases, Toxins and Vaccination

This realization, however, should come as no great surprise. After all, we are all different genetically, epigenetically. Consequently, each of us can react differently to diseases, environmental toxins and medical interventions such as vaccination.

“Each one of us is born with different genes and a unique microbiome influenced by epigenetics that affects how we respond to diseases and pharmaceutical products like vaccines,” says Barbara Loe Fisher, co-founder and president of the National Vaccine Information Center.11

One of the best examples of how genetic variation can determine the susceptibility of a race or ethnic group to disease is sickle-cell disease, which is more common in African and Mediterranean populations than in northern European populations. The opposite is the case for the genetic disorder cystic fibrosis and the condition known as hemochromatosis (iron overload).12

According to the Susan G. Komen Foundation, the chances of a woman developing breast cancer can be determined by her ethnic background. For example, white and black women are more likely to get breast cancer than Asian/Pacific Islander or Hispanic women.13

We are biologically diverse, and that can be a strength or a weakness, depending on the threats we face. This has perhaps never been more true than with the COVID pandemic and the COVID shots.

Many people, regardless of their limited exposure to the SARS-CoV-2 virus or vaccination status, came down with COVID. On the other hand, there were many people who, despite heavy exposure to SARS-CoV-2, never got COVID. “There are numerous examples of couples in which one partner got seriously ill, and the spouse was taking care of them yet did not get infected,” said András Spaan, MD, PhD, a clinical microbiologist at the St. Giles Laboratory of Human Genetics of Infectious Diseases at New York’s Rockefeller University.14

The same can be said for the COVID shots. Approximately 81 percent of the people in the United States received at least one dose of the available COVID shots. Some 70 percent of the people in the U.S. were “fully vaccinated,” meaning at least two doses or equivalent. Many of those people experienced no noticeable short-term harm from the shots. However, many of them did and were left with Long COVID Vaccination Syndrome (LCVS) or died.15 16 17

References:

1 GeneCards. ACE2 Gene – Angiotensin Converting Enzyme 2.
2 Horowitz JE. Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe diseaseNature Mar. 3, 2022.
3 National Library of Medicine. ACE2 angiotensin converting enzyme 2 [ Homo sapiens (human) ] July 16, 2023.
4 U.S. Centers for Disease Control and Prevention. COVID-19.
5 Rabaan AA. Genetic Variants and Protective Immunity against SARS-CoV-2Genes (Basel) Dec. 13, 2022; 13(12): 2355.
6 Ali F et al. ACE2 coding variants in different populations and their potential impact on SARS-CoV-2 binding affinity Biochem Biophys Rep December 2020; 24: 100798.
7 Hou Y et al. New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysisBMC Medicine July 15, 2020.
8 Bakhshandeh B. Variants in ACE2; potential influences on virus infection and COVID-19 severityInfect Genet Evol June 2021; 90: 104773.
9 Beyerstedt S. COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infectionEur J Clin Microbiol Infect Dis May 2021: 40(5): 905-919.
10 Ren W. Susceptibilities of Human ACE2 Genetic Variants in Coronavirus InfectionJ Virol Jan. 12, 2022; 96(1): e0149221.
11 Fisher BL. Vaccine Culture War Myths. National Vaccine Information Center.
12 Jorde LB, Wooding SP. Genetic variation, classification and ‘race’Nature Oct. 26, 2004.
13 PIH Health. Ethnicity and Disease Risk: What’s the Connection? Apr. 21, 2021.
14 Boyle P. Are some people immune to COVID-19? AAMC News Jan. 19, 2023.
15 USAFacts.org. US Coronavirus vaccine tracker.
16 The Vaccine Reaction. Risk & Failure Reports.
17 Parpia R. “Long COVID Vaccination Syndrome” and “Long COVID” Illness Are SimilarThe Vaccine Reaction July 17, 2023.

________________

**Comment**

Despite this peer-reviewed research, those of you with ears to the ground heard about the “poo storm” when Robert F. Kennedy spoke of this research and was recorded at a dinner party.  He was promptly accused of being a racist conspiracy theorist at what was described as a booze and fart-filled dinner.”

Journalists have truly lost their way.

A reasonable sequitur would be: since the injections use the same spike protein as COVID, the injections could also be potentially racially targeting.

But there’s another reason people are having different outcomes after the COVID shots:  the entire DOD program is an ongoing clinical experiment with different arms.  This simply means some people were told they got the gene therapy injection but actually got a placebo.  Others received a lower dose and other a higher dose.  However, no matter how you cut it, the shots are bad all around with 75% of deaths causally related to the shots.

But this research has been conveniently censored by The Lancet, because it too is an inconvenient truth.

A lot can be explained due to the microclotting being seen by doctors who are using D-dimer tests of “vaccinated” patients with adverse reactions. Embalmers are also finding arteries filled with clots in the “vaccinated”.  The most implicated organ system in COVID vaccine-associated death was the cardiovascular system (53 percent), followed by the hematological (blood) system (17 percent), the respiratory system (8 percent) and multiple organ systems (7 percent). The mean time from vaccination to death was 14.3 days, with most deaths occurring within a week from last administration of a shot.1

Research has also shown “vaccine” induced thrombocytopenia and thrombosis (VITT) and increased heart attacks.

This is also why aspirin and proteolytic enzymes like lumbrokinase, serrapeptase and nattokinase, (which has antiviral effects,) have been successful in helping to treat COVID as well as injuries caused by the injection.

It is high time these gene-therapy clot shots were banned

Wrongful Death Lawsuit Against Ascension Hospital

https://www.americaoutloud.news/grace-under-pressure-a-fathers-courage-to-face-the-biopharmaceutical-complex/

Grace Under Pressure – A Father’s Courage to Face the Biopharmaceutical Complex

by  | Apr 10, 2023

It is believed that Ernest Hemingway wrote that “courage [or guts] is grace under pressure.” What an intriguing way of putting it! In so many ways, this describes the relentless pursuit of a father seeking justice for his daughter’s death.

This week’s McCullough Report features an exclusive interview with Scott Schara, father of his late daughter, Grace. Scott and his family have been fighting for justice in order to help others who are facing similar situations. Here is an excerpt from a recent press release:

“March 29, 2023, Grace Schara, a 19-year-old with Down Syndrome, died at St. Elizabeth’s Hospital (Ascension) after medical personnel administered three drugs that, when given together, are known to hasten severe hypoxia– Precedex, Lorazepam, and Morphine. As Grace slipped into acute respiratory failure and Grace’s sister begged for help, instead of starting CPR immediately, the nurses refused; Grace’s physician had independently designated her as a “Do Not Resuscitate” (DNR). That DNR order was written without the family’s consent and in defiance of the Schara family’s express wishes that all lifesaving measures be deployed for their Down Syndrome daughter. As a result of the lethal cocktail of drugs and the fraudulent DNR order Grace died on Oct. 13, 2021. The Schara family will be filing a first of its kind lawsuit against St. Elizabeth’s Hospital (Ascension), and doctors and nurses related to the wrongful death of Grace Schara. The first step in the process is a request for mediation with the Director of State Courts, which will be filed on March 30. “St. Elizabeth’s not only breached the Standard of Care, but their unethical behavior led directly to Grace’s death,” stated father, Scott Schara. “It’s clear to me that this hospital was a dangerous place for Down Syndrome patients like my daughter. My Grace was discriminated against due to her disability and she received grossly subpar healthcare, in clear violation of the Americans with Disabilities Act.” Grace’s legal case will lay the groundwork for other hospital victims where their right to informed consent was denied and the patient suffered injury and death.”

See link for article and audio interview

_________________

**Comment**

I wrote about this unfortunate case which happened right here in Wisconsin:   https://madisonarealymesupportgroup.com/2022/02/14/stay-away-from-hospitals-if-you-can/

Excerpt:

An international lawyer with Disabled Rights Advocates and legal counsel to the Truth for Health Foundation describes how if a person goes into the hospital with even a broken arm, they will be tested for COVID, which has an extremely high false-positive rate.  If they don’t test positive immediately, they keep testing until they do. Then, the patient is admitted, put on an IV bag with a tranquilizer that lowers their oxygen absorption, which then justifies putting the patient into isolation and on the anti-viral remdesivir and then given morphine and fentanyl while being deprived of nutrition.

This completely evil racket comes from the WHO on down the line:

COVID protocols are passed down hierarchically from the World Health Organization (WHO) to Centers for Disease Control (CDC) and National Institute of Health (NIH), arising from the Public Readiness and Emergency Preparedness Act (PREP Act) and Health and Human Services authorization to release funding for the declared pandemic that sets the protocols in motion.

From there, hospitals that are federally funded through Centers for Medicare and Medicaid Services (CMS) use coding tied to NIH and CDC-written protocols. If hospitals take that funding, they must follow those protocols, starting with ICD-10 codes (International Classification of Diseases).

The CDC and NIH protocols are based on the WHO’s 2005 International Health Regulations that directs each of its 196 signatory countries to cede all sovereign powers to the WHO in the case of a declared health emergency.

The WHO then directs the various state health bodies—in this case, the CDC and NIH—on treatment, which is why every country is responding in the same way at the same time globally.

When these protocols are passed down to the hospitals that take funding, under the emergency declaration, patients’ rights are waived under the CMS COVID waiver program in conjunction with the PREP and CARES Act, giving participating hospitals legal immunity.

This is a perfect moment to insert a post from a 3rd year law student’s paper advocating for a “federal” solution to Lyme.  This isn’t just a “no,” this is a “hell no!”  I repeat: putting the power into the hands of the few will follow the ‘law of unintended consequences’ and will hurt patients and doctors in the end.  COVID is a PERFECT example.  Don’t do it!

Dr. Peterson Pierre explains the reason hospitals are killing COVID patients. The information is a reiteration of the excellent article written by Dr. Vliet. In short, in vast government overreach, the government is paying hospitals to do the wrong things.  The problem is so bad, some physicians have formed a new alliance, called the Pandemic Health Alliance and have drafted a “Physicians Declaration” and released it Sept. 12 at a global Covid summit in Rome, Italy.

This is also a perfect example why the ‘Pandemic Treaty’ would only make this worse as it hands over the keys to global government and pushes for global “vaccine” passports.  Especially now as the media have already begun their next “tripledemic” narrative in lockstep, but will never, ever, in a million years explain that the reason for concern over three viruses worsening is entirely due to the “vaccinated” and the subsequent ADE or pathogenic priming setting people up for immune overload and  more severe disease.

It’s a no-brainer.

July 29: World Ivermectin Day

Join our Twitter Space event this Saturday at 4pm UTC to hear real stories from real people that have successfully utilized Ivermectin!

Featuring: 🇬🇧 Dr Tess Lawrie, 🇿🇦 Shabnam Palesa Mohamed🇺🇸 Dr Pierre Kory🇨🇦 Dr Chris Shoemaker🇬🇧 Edmund Fordham, PhD🇿🇦 Terry Herholdt🇬🇧 Dr Tina Peers🇿🇦 Dr Shankara Chetty🇿🇼 Dr Jackie Stone🇮🇳 Dr Amitav Banerjee🇮🇳 Dr Lenny Da Costa, and many more!

Can’t make the live meeting? Don’t worry! You can find it in the Newsroom after the meeting or in the Video Library later this week.

Mind Health Meditation with Cameron Tukapua

Join us on Telegram this Wednesday for another guided meditation led by Cameron Tukapua.
After 10 years of acupuncture practice, Cameron was invited to teach at a Wellbeing retreat centre in Hawaii. She then started an Acupuncture College in Christchurch, New Zealand and also co-leads Wellbeing, Qigong, and Yoga retreats in China. Spreading holistic worldviews is the natural extension of her practice.

BWC Workshop with Dr Marik & Dr Myhill Now Available!

In this exclusive workshop, Dr Paul Marik and Dr Sarah Myhill share their extensive knowledge of what people can do to help recover from spike-induced vaccine injury.

Watch or share this important workshop now.

General Assembly Meeting #96 Now Available

General Assembly Meeting #96

On July 17, 2023, we heard from Cambel McLaughlinRev Dr Wai-Ching Lee, and Shabnam Palesa Mohamed at World Council for Health General Assembly Meeting #96.

Upcoming Events

General Assembly Meeting #97

Monday 24 July

Join us in the WCH Newsroom.

Mind Health Meditation

Wednesday 26 July

Join Cameron Tukapua on Telegram.

World Ivermectin Day 2023

Saturday 29 July

Learn more at WorldIvermectinDay.org.

Join our Twitter Space here.

Emerging Post Pandemic Diseases

29-30 August

Jam For Freedom Festival

An International Celebration of Music, Art and Life

3-6 August

Harlow, Essex

Learn more here. Jam for Freedom is now SOLD OUT.

Campout 2023

An International Celebration of Music, Art and Life

10-13 August

Oxfordshire, UK

Learn more and purchase tickets here.

MAAFIM International Conference

An International Celebration of Music, Art and Life

14-17 September

Kuala Lumpur, Malaysia

Learn more and purchase tickets here.

Click Here to Support the World Council for Health

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Paralyzed by Lyme, They Were Helped With Combo Treatments

https://www.lymedisease.org/remission-from-lyme-paralysis/

Paralyzed by Lyme, they were helped with combo treatments

By Lonnie Marcum

July 19, 2023

A new study from France looks at the use of combination antibiotics and anti-parasitic treatments in patients with limb paralysis as a result of tick-borne infections, including Lyme disease.

Approximately 70% of the patients in this study showed complete remission of symptoms after long-term treatment—a statistic that lines up with the MyLymeData treatment study.

The paper entitled, Complete Remission in Paralytic Late Tick-Borne Neurological Disease Comprising Mixed Involvement of Borrelia, Babesia, Anaplasma, and Bartonella: Use of Long-Term Treatments with Antibiotics and Antiparasitics in a Series of 10 Cases was published in Antibiotics.

The inclusion criteria for this study required a score of 4 or more on the Kurtzke EDSS disability scale; positive blood tests for one or more tick-borne pathogen (including Borrelia burgdorferi, Babesia, Anaplasma or Bartonella); and chronic general symptoms including fatigue, pain, and cognitive deficits lasting six or more months.

The Extended Disability Status Scale (EDSSis a tool commonly used to quantify the level of disability in patients with multiple sclerosis. The EDSS grades six bodily functions, including visual, brain, bowel/bladder and sensory functions, as well as the patients’ ability to walk and take care of themselves.

All 10 of the patients that qualified for this study were severely disabled with partial or complete paralysis in at least one limb. Five of the 10 required a wheelchair for mobility, and four required assistive devices like walking sticks to get around.

Complete remission for 7 out of 10

Following extended treatment, seven out of 10 patients (70%) showed complete remission of symptoms. Among the nine patients with positive Borrelia serology (along with co-infections), 77% obtained complete remission.

The treatment administered varied according to the patient’s infection profile. The majority of the patients received repeated oral regimens of azithromycin-doxycycline and azithromycin-doxycycline-rifampin plus a minimum of three 35-day cycles of IV ceftriaxone. The eight patients co-infected with Babesia (a parasite) were also administered anti-parasitic cycles of atovaquone–azithromycin. The mean duration of treatment was 20 months +/- 6 months. (Trouillas 2023)

Historically, patients with late-stage Lyme disease have poor outcomes to single regimens of 10-day IV ceftriaxone. (I’ve previously written about brain inflammation, and small fiber neuropathy found in patients with continuing symptoms after short-term treatment for Lyme disease.)

And we have decades of strong evidence that under-treatment with single antibiotics is consistent with persistent infection in animal studies. (Embers 2012)

Two weeks isn’t enough

As far back as 1990, Dr. Allen Steere co-authored a paper on patients with persistent late-stage neurological Lyme disease.

In this paper Dr. Steere and his co-authors state:

Months to years after the initial infection with B. burgdorferi, patients with Lyme disease may have chronic encephalopathy, polyneuropathy, or less commonly, leukoencephalitis. These chronic neurologic abnormalities usually improve with antibiotic therapy.

Six months after a two-week course of intravenous ceftriaxone (2 g daily), 17 patients (63 percent) had improvement, 6 (22 percent) had improvement but then relapsed, and 4 (15 percent) had no change in their condition.

Six months after treatment, more than one third of the patients either had relapsed or were no better. In addition, more than half had previously received antibiotic therapy thought to be appropriate for their stage of disease and still had progression of the illness. The likely reason for relapse is failure to eradicate the spirochete completely with a two-week course of intravenous ceftriaxone therapy. (Logigian 1990)

MyLymeData

In fact, the MyLymeData study validates that longer antibiotic treatment durationare associated with moderate to a very great deal of improvement. (Johnson 2020)

MyLymeData is currently the largest observational study of patients using real-world data to analyze the response to treatment of chronic Lyme disease patients. The majority of patients (57%) reported treatment durations of four or more months,

The results of this new French study demonstrate the importance of clinicians being able to continue treatment until a patient’s symptoms have resolved. It is clear, at least in this study, that the presence of co-infections greatly compounds one’s disease progress and treatment options.

LymeSci is written by Lonnie Marcum, a Licensed Physical Therapist and mother of a daughter with Lyme. She served two terms on a subcommittee of the federal Tick-Borne Disease Working Group. Follow her on Twitter: @LonnieRhea  Email her at: lmarcum@lymedisease.org.

References

Embers ME, Barthold SW, Borda JT, Bowers L, Doyle L, Hodzic E, et al. Persistence of Borrelia burgdorferi in Rhesus Macaques following Antibiotic Treatment of Disseminated Infection. PLoS ONE. 2012;7(1):e29914. Available at: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0029914.

 Johnson, L.; Shapiro, M.; Stricker, R.B.; Vendrow, J.; Haddock, J.; Needell, D. Antibiotic Treatment Response in Chronic Lyme Disease: Why Do Some Patients Improve While Others Do Not? Healthcare 2020, 8, 383. https://www.mdpi.com/2227-9032/8/4/383

Logigian EL, Kaplan RF, Steere AC. Chronic neurologic manifestations of Lyme disease. N Engl J Med. 1990 Nov 22;323(21):1438-44. doi: 10.1056/NEJM199011223232102. PMID: 2172819.

Trouillas P, Franck M. Complete Remission in Paralytic Late Tick-Borne Neurological Disease Comprising Mixed Involvement of Borrelia, Babesia, Anaplasma, and Bartonella: Use of Long-Term Treatments with Antibiotics and Antiparasitics in a Series of 10 Cases. Antibiotics. 2023; 12(6):1021. https://doi.org/10.3390/antibiotics12061021

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