Archive for the ‘vaccines’ Category

Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 in Vitro in Human Liver Cell Line

**UPDATE March 2022**

https://www.bitchute.com/video/l9DzGzNa5vM4/  Video Here (Approx. 6 Min)

The following scientific study has conclusively shown the mRNA spike protein coding from COVID shots are copied into human DNA. The process is called intracellular reverse transcription of mRNA.  Long-term consequences of the shots are unknown.

https://www.mdpi.com/1467-3045/44/3/73/htm

Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line

1Department of Clinical Sciences, Lund University, 20502 Malmö, Sweden
2Infection Medicine, Department of Clinical Sciences, Lund University, 22362 Lund, Sweden
*Author to whom correspondence should be addressed.
Academic Editor: Stephen Malnick
Curr. Issues Mol. Biol. 2022, 44(3), 1115-1126; https://doi.org/10.3390/cimb44030073 (registering DOI)
Received: 18 January 2022 / Revised: 19 February 2022 / Accepted: 23 February 2022 / Published: 25 February 2022
Abstract
Preclinical studies of COVID-19 mRNA vaccine BNT162b2, developed by Pfizer and BioNTech, showed reversible hepatic effects in animals that received the BNT162b2 injection. Furthermore, a recent study showed that SARS-CoV-2 RNA can be reverse-transcribed and integrated into the genome of human cells. In this study, we investigated the effect of BNT162b2 on the human liver cell line Huh7 in vitro. Huh7 cells were exposed to BNT162b2, and quantitative PCR was performed on RNA extracted from the cells. We detected high levels of BNT162b2 in Huh7 cells and changes in gene expression of long interspersed nuclear element-1 (LINE-1), which is an endogenous reverse transcriptase. Immunohistochemistry using antibody binding to LINE-1 open reading frame-1 RNA-binding protein (ORFp1) on Huh7 cells treated with BNT162b2 indicated increased nucleus distribution of LINE-1. PCR on genomic DNA of Huh7 cells exposed to BNT162b2 amplified the DNA sequence unique to BNT162b2. Our results indicate a fast up-take of BNT162b2 into human liver cell line Huh7, leading to changes in LINE-1 expression and distribution. We also show that BNT162b2 mRNA is reverse transcribed intracellularly into DNA in as fast as 6 h upon BNT162b2 exposure.

Important excerpts from Discussion section:

In the assessment report on BNT162b2 provided to EMA by Pfizer, the pharmacokinetic distribution studies in rats demonstrated that a relatively large proportion (up to 18%) of the total dose distributes to the liver [26].

In the current study, we employed a human liver cell line for in vitro investigation. It is worth investigating if the liver cells also present the vaccine-derived SARS-CoV-2 spike protein, which could potentially make the liver cells targets for previously primed spike protein reactive cytotoxic T cells. There has been case reports on individuals who developed autoimmune hepatitis [39] after BNT162b2 vaccination. To obtain better understanding of the potential effects of BNT162b2 on liver function, in vivo models are desired for future studies.
In the BNT162b2 toxicity report, no genotoxicity nor carcinogenicity studies have been provided [26]. Our study shows that BNT162b2 can be reverse transcribed to DNA in liver cell line Huh7, and this may give rise to the concern if BNT162b2-derived DNA may be integrated into the host genome and affect the integrity of genomic DNA, which may potentially mediate genotoxic side effects. At this stage, we do not know if DNA reverse transcribed from BNT162b2 is integrated into the cell genome. Further studies are needed to demonstrate the effect of BNT162b2 on genomic integrity, including whole genome sequencing of cells exposed to BNT162b2, as well as tissues from human subjects who received BNT162b2 vaccination.
The Pfizer EMA assessment report also showed that BNT162b2 distributes in the spleen (<1.1%), adrenal glands (<0.1%), as well as low and measurable radioactivity in the ovaries and testes (<0.1%) [26]. Furthermore, no data on placental transfer of BNT162b2 is available from Pfizer EMA assessment report. Our results showed that BNT162b2 mRNA readily enters Huh7 cells at a concentration (0.5 µg/mL) corresponding to 0.5% of the local injection site concentration, induce changes in LINE-1 gene and protein expression, and within 6 h, reverse transcription of BNT162b2 can be detected. It is therefore important to investigate further the effect of BNT162b2 on other cell types and tissues both in vitro and in vivo.
Conclusions: Our study is the first in vitro study on the effect of COVID-19 mRNA vaccine BNT162b2 on human liver cell line. We present evidence on fast entry of BNT162b2 into the cells and subsequent intracellular reverse transcription of BNT162b2 mRNA into DNA.
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**Comment**
Remember when Covidians stated that those who believe the shots are gene therapy are “conspiracy theorists?”
For more:

Florida First State to Allow Doctors to Use Off-Label Drugs for Early Treatment of COVID-19 & Recommend Against COVID Shots For Kids

https://www.theepochtimes.com/florida-first-state-to-allow-doctors-to-use-off-label-drugs-for-early-treatment-of-covid-19

Florida First State to Allow Doctors to Use Off-Label Drugs for Early Treatment of COVID-19

By Meiling Lee
March 3, 2022

Repurposed drugs that have been shown to prevent or treat COVID-19 may be prescribed by physicians, the Florida Department of Health said in its new COVID-19 guidance for health care practitioners.

The guidance, published on Feb. 24, says that health care practitioners are encouraged to provide early treatment for COVID-19 patients with federally approved generic drugs that they find to work. This is in addition to the outpatient treatments granted emergency authorization usage (EUA) for people at risk of developing a serious illness.

“When recommending COVID-19 treatment options for patients’ individualized health care needs, physicians should exercise their individual clinical judgment and expertise based on their patient’s needs and preferences,” the guidance states. “These options may include emerging treatments backed by quality evidence, with appropriate patient informed consent, including off-label use or as part of a clinical trial.”

The new guidance is an effort by Republican Gov. Ron DeSantis to offer health care practitioners protection from lawsuits. He said that it’s important for doctors to be able to have access to these drugs.  (See link for article)

__________________

SUMMARY:

  • DeSantis also paves a way for doctors to report to the Agency for Health Care Administration if their hospital prevents them from treating their patients who wish to try medications not recommended by the federal health agencies.
  • Florida is the first and only state go go against the CDC’s recommendation to ‘get sicker.’
  • Dr. Pierre Kory, president of FLCCC states many have died needlessly and that the government’s only focus is pushing gene therapy injections. He also states effective treatments have been available for 2 years but the government is still injecting people with a 2-year old shot against a variant which is extinct.
  • Kory states the EUA antiviral drugs (Paxlovid and molnupiravir) are toxic and poisonous.
  • Further, there are concerns COVID may develop resistance to these EUA antivirals because each only attacks 1 part of the virus instead of the multifaceted approach like ivermectin.
  • An article in Nature shows the importance of an antiviral targeting a polymerase and a protease to successfully eliminate a virus.
  • Then there’s the cost issue.
    • Molnupiravir costs the government $530 for 2 pills a day for 5 days
    • Paxlovid costs the government $700 for 2 pills a day for 5 days
    • ivermectin costs as low as $30 and as high as $94 for 20 tablets
  • In an ICER report (pdf) examining the outpatient treatments for COVID-19 the authors raised concerns about the effectiveness and safety of the drugs due to lack of long-term data and lack of peer review.  Yet, the FDA issued EUA for these expensive, questionable, toxic drugs while recommending against ivermectin and still states the most effective way to limit the spread of COVID is by the gene therapy injections which don’t stop transmission or infection, keep you from being hospitalized or from dying, and have caused more adverse reactions and death than any other vaccine in the history of VAERS.

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https://www.theepochtimes.com/florida-to-become-first-state-to-recommend-against-covid-19-vaccines-for-healthy-children

Florida to Become First State to Recommend Against COVID-19 Vaccines for Healthy Children

By Zachary Stieber
March 7, 2022

Florida officials on March 7 said the state would be the first to formally recommend that healthy children shouldn’t get a COVID-19 vaccine.

Dr. Joseph Ladapo, the state’s surgeon general, made the announcement during a roundtable discussion titled “The Curtain Close on COVID Theater.”

“The Florida Department of Health is going to be the first state [department] to officially recommend against the COVID-19 vaccines for healthy children,” Ladapo said.  (See link for article)

Every single state needs to pass legislation exactly like this.
Medicine needs to be decentralized.  Doctors need to be given back their power to treat patients.

But, true to form, White House press secretary Jen Psaki, who is NOT a doctor or health expert, condemned Ladapo as a “politician” who is “peddling conspiracy theories,” despite being a Harvard trained MD/PhD who has worked at NYU, UCLA, the FDA, and the University of Florida.  Psaki presents a perfect example of what Weinstein and Heying (both PhD’s) discuss in a recent video where we must get used to living in a world where things are labeled upside down (up is down, right is left, and inclusive is exclusive, etc.).  And the corrupt IDSA also accuses Florida of putting “politics over the health and safety of children.”

Doctors need to freely treat without fear of persecution. This would also help more doctors be willing to learn and willing to treat Lyme/MSIDS as well as other politicized diseases.  Regulatory agencies and public health are captured agencies that are completely corrupt. A perfect example: the AMA had no trouble when the Biden Administration gave pharmacists, dentists, optometrists, podiatrists, and even veterinarians the power to administer COVID-19 injections, with the Prep Act protecting them from lawsuits if the injected person dies or is injured, but now is complaining that Biden’s “Test to Treat” plan “flaunts patient safety and risks significant negative health outcomes,” by allowing the nations largest pharmacy chains with onsite clinics, long-term care centers, community health centers, and veterans’ health centers to dispense anti-virals to people who test positive. They are all of a sudden worried about a patient’s medical history for treatment but don’t give a fig about considering this same medical history for experimental injections that have caused more adverse events and death than any vaccine in the history of VAERS.  Anyone else smell a rat?  The antivirals; however, will not be ivermectin or HCQ, but FDA “approved” drugs by Pfizer and Merck, which have 6 pages of drug interactions and use restrictions, not to mention are expensive. When listening to both sides it becomes evident that behind it all is a power grab with a lot of money involved.  Once again, patients are way down the priority list.

Wisconsinites: Action Needed for AB 316 – Prohibit Discrimination Based on Vaccination Status

Dear Wisconsin NVIC Advocacy Team Members,

You have the opportunity to support a good bill, AB 316,  which would prohibit governmental entities in Wisconsin from discriminating against individuals based on their COVID-19 vaccination status or whether they have proof of receiving a COVID-19 vaccine. AB 316 is on the Senate Calendar for Tuesday, March 8th, 2022. 

ACTION NEEDED:

1) Contact your Wisconsin State Senator and ask him or her to vote in favor of AB 316! Please see talking points below. If you do not know who your Wisconsin state senator is, login to the NVIC Advocacy Portal at http://NVICAdvocacy.org. Click on “Who Represents Me” on the home page or “My State” on the STATE TEAMS tab. Your personal state legislators are listed on the bottom of the page. You can click on your legislators’ names to get phone numbers, emails, and even links to their social media to connect to them. You can also find your state senator at this link: https://maps.legis.wisconsin.gov/

2) Please share this email with family and friends, or you can tell them to go to http://NVICAdvocacy.org and click on the alert for Wisconsin AB 316.

3) Login to the NVIC Advocacy Portal OFTEN to check for updates.  http://NVICAdvocacy.org. We review bills and make updates daily. Bills can change many times over the legislative process and your timely visits, calls, and emails directed at the correct legislators are critical to this process.

TALKING POINTS (Please personalize to share how this bill affects you and your family):

  • AB 316 would prohibit discrimination based on COVID-19 vaccination status by the state and other governmental entities in Wisconsin.
  • Any form of discrimination against individuals unvaccinated against COVID-19 is essentially a form of coercion to try and get them vaccinated by implementing barriers to navigate life.
  • It is unreasonable to penalize perfectly healthy individuals who simply have not received a particular vaccine.
  • This bill would prohibit government-sponsored COVID-19 vaccine discrimination, allowing residents of Wisconsin to freely participate with their state and local governments.
  • It would also ensure that the residents of Wisconsin are allowed to access needed state and local government facilities and services without fear of discrimination based on their COVID-19 vaccination status.
  • State and local governments are taxpayer-funded and exist to serve the public. Since there is no vaccine requirement for paying taxes, there should be no chance of a vaccine requirement for accessing or using government facilities and services, or as a prerequisite for any other type of interaction with the government.
  • Passing this bill would also clarify that there is no state requirement or expectation of private persons and entities in Wisconsin to mandate COVID-19 vaccines or to require proof of vaccination.
  • Even individuals who are vaccinated against COVID-19 can still spread and catch it. COVID-19 vaccine requirements or mandates reduce the focus from health to mere vaccine status.
  • Our American system of government was founded upon protecting the rights of individuals. This protection entails prohibiting the intrusion upon these rights from other individuals and entities, including the government itself.

Sincerely,

NVIC Advocacy Team
National Vaccine Information Center
http://NVIC.org and http://NVICAdvocacy.org
https://nvicadvocacy.org/members/Members/ContactUs.aspx

Make A Difference, support NVIC. NVIC is a certified 501(c)3 Charity.

The National Vaccine Information Center (NVIC) works diligently to prepare and disseminate our legislative advocacy action alerts and supporting materials.  We request that organizations and members of the public forward our alerts in their original form to assure consistent and accurate messaging and effective action. Please acknowledge NVIC as originators of this work when forwarding to members of the public and like-minded organizations. To receive alerts immediately, register  at http://NVICAdvocacy.org, a website dedicated to this sole purpose and provided as a free public service by NVIC. 

For a rousing pro-medical freedom, anti-segregation speech by a civil rights attorney who flatly states “vaccine” mandates are illegal and a form of medical rape:  https://rumble.com/vs33yz-tricia-lindsay.html

Former WHO Consultant Exposes Ivermectin Takedown

Again, Lyme/MSIDS patients need to understand that when corrupt public health authorities and governmental agencies censor and ban what they consider ‘misinformation,’ patients will be negatively impacted as dissenting opinions will not be allowed.  This has happened for 40 years in Lymeland and now is being seen in COVID. The following information is an important lesson that is imperative to know or we will find ourselves without any help whatsoever from medicine.  As it is, we must find Lyme literate doctors (LLMDs) who defy the accepted narrative that Lyme is hard to catch, and easy to treat and that uses abysmal testing that misses nearly everyone, leaving thousands upon thousands to suffer in silence.  Please share this info widely so people are educated on what is happening.

https://thehighwire.com/videos/former-w-h-o-consultant-exposes-takedown-of-ivermectin/  Video Here (Approx 55 Min)

FORMER W.H.O. CONSULTANT EXPOSES TAKEDOWN OF IVERMECTIN

Del sits down for a one-on-one with the former W.H.O. consultant & research scientist, Tess Lawrie MD, PhD, who was a critical part of the Ivermectin trials over a year ago with overwhelmingly positive conclusions. See data and recorded personal zoom calls that reveal how a key review was attacked from within, keeping the safe, life-saving drug out of the hands of millions of dying Covid patients for more than a year.
This is a mind-blowing expose on how Ivermectin was covered up. There have been too many scenarios, just like this one, where a well-meaning doctor or scientist appears to be doing the right thing, trying to show the truth about the efficacy (or non-efficacy) of a drug, until suddenly, they start acting very strangely, they are no longer being ethical, and won’t admit why.  Money and coercion are typically at the root of these scenarios, and sadly, this is just one more case where – what do you know – as it turns out, The Gates Foundation seems to have been one of the major factors in this cover-up.  Source  (I highly recommend utilizing this sourcelink as there is a plethora of information within it including interviews and data.)
For more:

‘Truly Frightening:’ Feds Give Tech Companies Until May 2 to ‘Turn Over COVID-19 Misinformation’

Lyme/MSIDS patients need to understand that when the government attacks free speech and dissenting medical opinions, it’s just a matter of time before the ‘eye or Mordor’ swings to any subject that they deem ‘misinformation,’ including but not limited to Lyme/MSIDS, vaccines, autism, MS, and more.

https://childrenshealthdefense.org/defender/feds-tech-companies-turn-over-covid-19-misinformation/

‘Truly Frightening:’ Feds Give Tech Companies Until May 2 to ‘Turn Over COVID-19 Misinformation’

Two U.S. Senators this week introduced a bill that could criminalize First Amendment rights, while the U.S. Surgeon General formally demanded tech companies turn over data on organizations and individuals who post “COVID-19 misinformation” on social media platforms.

Two news stories this week reveal how the federal government plans to treat COVID “misinformation” as a crime, and what role tech companies will play in rounding up the “criminal.”

This is truly frightening.

Two U.S. Senators this week introduced a bill to provide tech companies cover via legislation that could make it possible for Congress to “legalize” censorship and criminalize First Amendment rights to freedom of speech.

Here’s a press release describing the bill:

“U.S. Senators Ben Ray Luján (D-N.M.) and Chris Murphy (D-Conn.), both members of the U.S. Senate Committee on Health, Education, Labor and Pensions, on Wednesday introduced legislation to counter the threat that misinformation and disinformation pose to public health as evidenced by the widespread false narratives throughout the COVID-19 pandemic.

“The Promoting Public Health Information Act would support efforts across the U.S. Department of Health and Human Services and with outside stakeholders to communicate effectively during a public health emergency and address health misinformation.”

Here is what Murphy had to say about the bill:

“Throughout this pandemic, the impact of misinformation has been devastating. Rumors and conspiracy theories about the efficacy of masking or the safety of vaccines still run rampant on social media and have caused thousands of deaths that could have been prevented.

“This legislation will help us get smart about how to tackle misinformation and effectively promote science-based health information, especially as we continue fighting COVID-19 and prepare for future public health emergencies.”

In other words, the feds are asking detailed information about the demographics “exposed to misinformation,” allowing them to determine who’s reading what, and to obtain their names.

Next, in the last paragraph of this New York Times article, “The surgeon general calls on Big Tech to turn over Covid-19 misinformation data,” we learn that the federal government wants citizens to start “sharing” information on “misinformation:”

“‘We’re asking anyone with relevant insights — from original research and data sets to personal stories that speak to the role of misinformation in public health — to share them with us,’ Dr. [Vivek] Murthy said.”

Isn’t that sweet?

This is how they dress up the Stasi in 21st-century euphemism to encourage ratting out your friends and neighbors: “Please share with the feds. They care what you think.”

Sure they do.

According to the Times:

“President Biden’s surgeon general on Thursday formally requested major tech platforms submit information about the scale of COVID-19 misinformation on social networks, search engines, crowdsourced platforms, e-commerce platforms and instant messaging systems.

“The request for information from the surgeon general’s office demanded tech platforms send data and analysis on the prevalence of COVID-19 misinformation on their sites, starting with common examples of vaccine misinformation documented by the Centers for Disease Control and Prevention.

“The notice asks the companies to submit ‘exactly how many users saw or may have been exposed to instances of COVID-19 misinformation,’ as well as aggregate data on demographics that may have been disproportionately exposed to, or affected by, the misinformation.

“The surgeon general, Dr. Vivek Murthy, also demanded information from the platforms about the major sources of Covid-19 misinformation, including those that engaged in the sale of unproven Covid-19 products, services and treatments.

“‘Technology companies now have the opportunity to be open and transparent with the American people about the misinformation on their platforms,’” Murthy said in an emailed statement. He added: “‘This is about protecting the nation’s health.’”

“Companies have until May 2 to submit the data. Denying requests for information does not carry a penalty, but the notice is the first formal request from the Biden administration of the tech companies to submit COVID-19 misinformation data, according to the surgeon general’s office.

“Six months ago, Murthy used his first formal advisory to the U.S. to deliver a broadside against tech and social media companies, which he accused of not doing enough to stop the spread of dangerous health misinformation — especially about COVID-19. He called the misinformation “an urgent threat to public health.”

“The request for information is part of President Biden’s National COVID-⁠19 Preparedness Plan, which the White House detailed on Wednesday and which is a road map for a new stage of the pandemic where COVID-19 causes ‘minimal disruption,’ according to the White House.

Biden first revealed details of the plan during his State of the Union address Tuesday night.

“In addition to demanding misinformation data from the tech platforms, the surgeon general called on healthcare providers and the public to submit information about how COVID-19 misinformation has negatively influenced patients and communities.

“‘We’re asking anyone with relevant insights — from original research and data sets to personal stories that speak to the role of misinformation in public health — to share them with us,’” Murthy said.”

The views and opinions expressed in this article are those of the authors and do not necessarily reflect the views of Children’s Health Defense.