Archive for the ‘Testing’ Category

Royalties & Profits Over Patient Care Part 2

Go here for Part 1.

https://www.change.org/p/the-us-senate-calling-for-a-congressional-investigation-of-the-cdc-idsa-and-aldf

Patent royalties and pharmaceutical profits over lifesaving care? (Part 2)

Carl Tuttle

Hudson, NH, United States

JAN 12, 2023 — 

We have been shouting from the rooftops for decades!! No one listened.

Now through the current pandemic the rest of the world is waking up to a False Public Health Narrative.

What you are about to read set the stage for “Safe and Effective”

-Manipulated diagnostic tests

-Suppression of the truth, facts, and scientific references

-Persecution of doctors who did not conform to published IDSA treatment protocols

-False Public Health Narrative; “Hard to catch and easy to treat”

After experiencing Covid, Now do you believe us?

Patent royalties and pharmaceutical profits over lifesaving care? Sound familiar?

2nd letter to Dattwyler (See previous update for part1)

——— Original Message ———-
From: CARL TUTTLE <runagain@comcast.net>
To: “Raymond_Dattwyler@nymc.edu” <Raymond_Dattwyler@nymc.edu>
Cc: “npjvaccines@nature.com” <npjvaccines@nature.com>, “abarrett@utmb.edu” <abarrett@utmb.edu>, “R.W.Titball@exeter.ac.uk” <R.W.Titball@exeter.ac.uk>, “mgomesso@uthsc.edu” <mgomesso@uthsc.edu>
Date: 01/11/2023 10:46 AM
Subject: Re: The year that shaped the outcome of the OspA vaccine for human Lyme disease
Dr. Dattwyler

As a follow-up to my inquiry questioning patent royalties and pharmaceutical profits over lifesaving care, you failed to mention in your manuscript that Western blot reporting criteria was manipulated in 1995 to facilitate vaccine development. (Dearborn Conference)

That manipulation led to a reduction in diagnostic success rate to 31% as reported by Dr. Paul Fawcett during the 1995 Rheumatology Symposia:

1995 Rheumatology Symposia Abstract# 1254 Dr. Paul Fawcett et al.

See full Abstract here

Dr. Fawcett has been the head of the research and clinical immunology laboratories since 1986. In addition, he serves as Chair of the IACUC and is a member of the IRB.
Source: https://www.nemoursresearch.org/snap/node/11969

Even more significant is Dennis Parenti’s 1998 vaccine presentation (Lyme.org at 1 hr 9 minutes). Dr. Parenti, medical director of the vaccine trial – the largest Lyme trial in history, discusses the research findings of seronegative Lyme. At 36% it is a common presentation. This proves that a negative western blot is meaningless. Since their patients were culture positive and/or DNA positive for Borrelia infection and western blot negative. Those patients would never get treatment because of the false standard. Despite the CDC knowing this, HHS knowing this, physician harassment continued unabated. This means that our own government was cherry-picking scientific findings to force false science on public health and block the public from getting the medical care they needed.

Once again, patent royalties and pharmaceutical profits over lifesaving care.

Slide from Dennis Parenti’s 1998 vaccine presentation:

See slide here_________________________________________________________

Seronegative Lyme does not prove:
1. A vaccine prevented disease:
2. A patient does not have Lyme disease;
3. Malpractice by doctors who treat them for disease;
4. An antibiotic has eradicated the disease;
5. A relapse is not occurring.

Seronegative Lyme is another clue of how the pathogen disables the patient’s immune system. That is the message by the bacterium to researchers, not that the patient does not have Lyme disease.

“Every research study that uses and article referencing seronegative Lyme to indicate any of the above is fraudulent and should not be used. Almost all protocols ignore this fact!!!” -Karen Vanderhoof-Forschner, Lyme Disease Foundation (founded in 1988)

_______________________________________________
The pursuit of patent royalties and pharmaceutical profits has caused unimaginable pain and suffering all across America!
Carl Tuttle
Hudson, NH

Cc: Alan D.T. Barrett, PhD Editor-in-Chief

Rick Titball, PhD, DSc, Deputy Editor

Lyme Disease Foundation
Willy Burgdorfer
Lyme Disease Foundation
Please share as widely as possible, especially to member of state medical licensing boards and state health departments. Remember, Dave Dennis, the cdc Lyme project officer was allowed to consult $$ directly with SKB. He…

Thanks to your support this petition has a chance at winning! We only need 51,419 more signatures to reach the next goal – can you help?

Category:

Activism, Lyme, Testing, vaccines

Patent Royalties & Pharma Profit Over Lifesaving Care

https://www.change.org/p/the-us-senate-calling-for-a-congressional-investigation-of-the-cdc-idsa-and-aldf

Patent royalties and pharmaceutical profits over lifesaving care?

Carl Tuttle

Hudson, NH, United States
Dr. Raymon Dattwyler 

JAN 8, 2023 — 

Please see the following letter addressed to Dr. Raymond Dattwyler who owns 24 patents for Lyme disease that include diagnostic testing and vaccines both live bacteria and oral.

Gomes-Solecki co-owns 17 patents with Dattwyler.

To view these patents, go to…

Patent Public Search Basic
https://ppubs.uspto.gov/pubwebapp/static/pages/ppubsbasic.html

———- Original Message ———-

From: CARL TUTTLE <runagain@comcast.net>
To: “Raymond_Dattwyler@nymc.edu” <Raymond_Dattwyler@nymc.edu>
Cc: “npjvaccines@nature.com” <npjvaccines@nature.com>, “abarrett@utmb.edu” <abarrett@utmb.edu>, “R.W.Titball@exeter.ac.uk” <R.W.Titball@exeter.ac.uk>, “mgomesso@uthsc.edu” <mgomesso@uthsc.edu>
Date: 01/06/2023 2:46 PM
Subject: The year that shaped the outcome of the OspA vaccine for human Lyme disease

npj Vaccines Jan 2022

The year that shaped the outcome of the OspA vaccine for human Lyme disease
https://www.nature.com/articles/s41541-022-00429-5

Raymond J. Dattwyler & Maria Gomes-Solecki

Department of Microbiology and Immunology
New York Medical College
Valhalla, NY
Raymond J. Dattwyler, Corresponding Author

Dear Dr. Dattwyler,

I read your manuscript with great interest as you call attention to a treatment-resistant Lyme arthritis with “no evidence of DNA” found in the joints of patients after antibiotic treatment.

For some strange reason however, I could not find the following 1995 publication within your paper identifying treatment-resistant neuroborreliosis:

European Neurology 1995

Seronegative Chronic Relapsing Neuroborreliosis
https://www.karger.com/Article/Abstract/117104

Lawrence C., Lipton R.B., Lowy F.D., Coyle P.K.d

Abstract

We report an unusual patient with evidence of Borrelia burgdorferi infection who experienced repeated neurologic relapses despite aggressive antibiotic therapy. Each course of therapy was associated with a Jarisch-Herxheimer-like reaction. Although the patient never had detectable free antibodies to B. burgdorferi in serum or spinal fluid, the CSF was positive on multiple occasions for complexed anti-B. burgdorferi antibodies, B. burgdorferi nucleic acids and free antigen.

____________________________________________

In fact, Dr. Dattwyler there seems to be a great deal of “treatment-resistant” evidence published in multiple journals over the past three decades:

Peer Reviewed Evidence of Persistence of Lyme Disease Spirochete Borrelia burgdorferi and Tick-Borne Diseases (700 References)
https://www.dropbox.com/s/n09sk90eo6xz7ua/700%20articles%20LYME%20EvidenceofPersistence-V2.pdf?dl=0

So that brings me to the reason for this email…

Question:

Does a chronic relapsing seronegative disease fit the vaccine model? If not, would that, in and of itself, be the hidden reason for denying chronic (treatment-resistant) Lyme disease for almost three decades?  In other words, patent royalties and pharmaceutical profits over lifesaving care?

A response to this inquiry is requested.

Carl Tuttle
Hudson, NH

Cc: Alan D.T. Barrett, PhD Editor-in-Chief
Rick Titball, PhD, DSc, Deputy Editor

Letter to the Editor of the BMJ published June 2020
https://www.bmj.com/content/369/bmj.m1041/rr-1

________________

**Comment**

We can thank Tuttle for doggedly pursuing fraud and corruption that is truly shackling thousands of sick patients to an obsolete model that is neither scientific nor logical.

BTW: the corruption continues:

Category:

Activism, Lyme, Testing, vaccines

Genomic Confirmation of Borrelia garinii, United States

https://wwwnc.cdc.gov/eid/article/29/1/22-0930_article

Volume 29, Number 1—January 2023
Natalie RudenkoComments to Author , Maryna Golovchenko, Ales Horak, Libor Grubhoffer, Emmanuel F. Mongodin1, Claire M. Fraser, Weigang Qiu, Benjamin J. Luft, Richard G. Morgan, Sherwood R. Casjens, and Steven E. Schutzer
 
 

Abstract

Lyme disease is a multisystem disorder primarily caused by Borrelia burgdorferi sensu lato. However, B. garinii, which has been identified on islands off the coast of Newfoundland and Labrador, Canada, is a cause of Lyme disease in Eurasia. We report isolation and whole-genome nucleotide sequencing of a B. garinii isolate from a cotton mouse (Peromyscus gossypinus) in South Carolina, USA. We identified a second B. garinii isolate from the same repository. Phylogenetic analysis does not associate these isolates with the previously described isolates of B. garinii from Canada.

_________________

Important excerpt:

How and when B. garinii arrived in South Carolina remains unknown. There were no reported Lyme disease outbreaks in the southeastern United States in humans at the time the strains were deposited in the repository or during the subsequent 2 decades. This finding minimizes the urgency for an immediate new search for B. garinii in this region. Nonetheless, clinical vigilance for B. garinii in humans in this region seems warranted.

 

True to form, the CDC downplays the finding of a new strain which very well could explain why sick patients continue to be mis or undiagnosed due to faulty testing and strain diversity, which will never be picked up using current 2-tiered CDC testing because it doesn’t look for other strains.

But, truth be damned.  It just doesn’t matter to corrupt public health.

Category:

Lyme, research, Testing, Ticks

3 Reasons Lyme/MSIDS Patients Remain Sick: Dormancy/Persisters, Biofilm, Co-Infection

https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-019-3495-7

Metamorphoses of Lyme disease spirochetes: phenomenon of Borrelia persisters

Parasites & Vectors volume 12, Article number: 237 (2019) Cite this article

Abstract

The survival of spirochetes from the Borrelia burgdorferi (sensu lato) complex in a hostile environment is achieved by the regulation of differential gene expression in response to changes in temperature, salts, nutrient content, acidity fluctuation, multiple host or vector dependent factors, and leads to the formation of dormant subpopulations of cells. From the other side, alterations in the level of gene expression in response to antibiotic pressure leads to the establishment of a persisters subpopulation. Both subpopulations represent the cells in different physiological states. “Dormancy” and “persistence” do share some similarities, e.g. both represent cells with low metabolic activity that can exist for extended periods without replication, both constitute populations with different gene expression profiles and both differ significantly from replicating forms of spirochetes. Persisters are elusive, present in low numbers, morphologically heterogeneous, multi-drug-tolerant cells that can change with the environment. The definition of “persisters” substituted the originally-used term “survivors”, referring to the small bacterial population of Staphylococcus that survived killing by penicillin. The phenomenon of persisters is present in almost all bacterial species; however, the reasons why Borrelia persisters form are poorly understood. Persisters can adopt varying sizes and shapes, changing from well-known forms to altered morphologies. They are capable of forming round bodies, L-form bacteria, microcolonies or biofilms-like aggregates, which remarkably change the response of Borrelia to hostile environments. Persisters remain viable despite aggressive antibiotic challenge and are able to reversibly convert into motile forms in a favorable growth environment. Persisters are present in significant numbers in biofilms, which has led to the explanation of biofilm tolerance to antibiotics. Considering that biofilms are associated with numerous chronic diseases through their resilient presence in the human body, it is not surprising that interest in persisting cells has consequently accelerated. Certain diseases caused by pathogenic bacteria (e.g. tuberculosis, syphilis or leprosy) are commonly chronic in nature and often recur despite antibiotic treatment. Three decades of basic and clinical research have not yet provided a definite answer to the question: is there a connection between persisting spirochetes and recurrence of Lyme disease in patients?

______________

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287027/

The Emerging Role of Microbial Biofilm in Lyme Neuroborreliosis

Enea Gino Di Domenico,1,* Ilaria Cavallo,1 Valentina Bordignon,1 Giovanna D’Agosto,1 Martina Pontone,1 Elisabetta Trento,1 Maria Teresa Gallo,1 Grazia Prignano,1 Fulvia Pimpinelli,1 Luigi Toma,2 and Fabrizio Ensoli1
Author information Article notes Copyright and License information Disclaimer
 

Abstract

Lyme borreliosis (LB) is the most common tick-borne disease caused by the spirochete Borrelia burgdorferi in North America and Borrelia afzelii or Borrelia garinii in Europe and Asia, respectively. The infection affects multiple organ systems, including the skin, joints, and the nervous system. Lyme neuroborreliosis (LNB) is the most dangerous manifestation of Lyme disease, occurring in 10–15% of infected individuals. During the course of the infection, bacteria migrate through the host tissues altering the coagulation and fibrinolysis pathways and the immune response, reaching the central nervous system (CNS) within 2 weeks after the bite of an infected tick. The early treatment with oral antimicrobials is effective in the majority of patients with LNB. Nevertheless, persistent forms of LNB are relatively common, despite targeted antibiotic therapy. It has been observed that the antibiotic resistance and the reoccurrence of Lyme disease are associated with biofilm-like aggregates in B. burgdorferi, B. afzelii, and B. garinii, both in vitro and in vivo, allowing Borrelia spp. to resist to adverse environmental conditions. Indeed, the increased tolerance to antibiotics described in the persisting forms of Borrelia spp., is strongly reminiscent of biofilm growing bacteria, suggesting a possible role of biofilm aggregates in the development of the different manifestations of Lyme disease including LNB.

________________

https://www.fortunejournals.com/articles/serological-and-pcr-evidence-of-infection-in-105-patients-with-sppt.html

Serological and PCR evidence of Infection in 105 Patients with SPPT

Alexis Lacout1*, Marie Mas4, Michel Franck2, Véronique Perronne3, Julie Pajaud2, Pierre Yves Marcy5, Christian Perronne3

*Corresponding Author: Alexis Lacout, Centre de diagnostic ELSAN, Centre Médico–Chirurgical, 83 avenue Charles de Gaulle, 15000, Aurillac, France

Received: 11 December 2020; Accepted: 22 December 2020; Published: 05 January 2021

Citation: Alexis Lacout, Marie Mas, Michel Franck, Véronique Perronne, Julie Pajaud, Pierre Yves Marcy, Christian Perronne. Serological and PCR evidence of Infection in 105 Patients with SPPT. Archives of Microbiology & Immunology 5 (2021): 139-150.

Abstract

Introduction: The main aim of this study is to determine the nature of the exposure of patients presenting with polymorphic signs and symptoms to the parasite Babesia, through the study of serology. The secondary aim is to report the different serological or PCR results observed in these patients.

Material and methods: The following serologies were performed in all patients looking for: Babesia divergens, Borrelia, Bartonella, Coxiella burnetii, Anaplasma phagocytophilum. The following PCRs were performed looking for: Borrelia spp, Babesia spp, Bartonella (Bartonella spp, B. quintana, B. Henselae,) Coxiella spp, Anaplasma spp, Ehrlichia spp, Rickettsia spp, most often on several matrices (venous blood, capillary blood, urine and saliva).

Results: In this study, 105 patients were included, 62 females and 43 males, sex ratio F/M was 62/43 = 1.44; mean age was 45.5 year old (range; 5 years, 79 years old).

  • Of the 105 serologies for B. divergens, 41% were found to be positive.
  • Of the 104 serologies for Borrelia, 19.2% were found to be positive.
  • Of the 95 serologies for Anaplasma, 27.3% were found to be positive.

Borrelia spp, Babesia spp, Bartonella spp, Coxiella spp, Anaplasma spp, Ehrlichia spp, Rickettsia spp were found by using rtPCR.

Conclusion: Our study has shown that patients with SPPT/PTLDS, a syndrome close to fibromyalgia, could harbor several tick borne microorganisms. Microbiologic analyses should thus not be merely limited to Borrelia’s research alone.

______________

**Comment**

These relatively recent studies (within the past few years) reveal what Lyme literate doctors and their patients have been experiencing from the beginning.  They also reaffirm what many independent researchers have globally been writing about for years.  There are many other reasons patients remain ill as well but these three are biggies.

Yet, reality is best summed up by the following quote from the first study listed above:

Three decades of basic and clinical research have not yet provided a definite answer to the question: is there a connection between persisting spirochetes and recurrence of Lyme disease in patients?

Isn’t that sad?

The same, of course, can be said of biofilm and coinfections as well. Decades have gone by with no definitive answers because The Cabal doesn’t want the truth to be known. Why? Quite simple: a chronic, relapsing illness doesn’t fit their “vaccine” narrative which is the favored golden calf and cash cow of research institutions and our government, which have a cozy relationship with Big Pharma and Big Media.  This is quite convenient for all of them as they control all the messaging as well as threaten, censor, and ban doctors who dissent.

This has been blatantly exposed during the time of COVID but is nothing new.  Lymeland has been riddled with the exact same issues for 40 years.  Unfortunately, even well-meaning advocates and patients evidently can not see this and continue to demand more money and become giddy when they get it from the very agencies behind this debacle, who are incidentally profiting from it.

It’s a hot-mess for sure, but one thing is certain: we must stop playing into their hands by being ignorant or filled with “hopium,” a term I use to describe how hope can become a drug that stops you from thinking critically, logically, and honestly.

For more:

Category:

Anaplasmosis, Babesia, Bartonella, Biofilm, Ehrlichiosis, Lyme, research, Rickettsia, Testing

Lyme Disease Videos From Leading LLMDs

https://www.lymedisease.org/members/resources/resources-lyme-disease-videos/

Preview of Member Videos from Leading Lyme Literate Physicians

Full videos available to members on the account page. You must be logged in to view.
Videos cover:
  • Diagnosis and Treatment
  • Using Integrative Medicine for Lyme
  • Treatment Protocols
  • Basic Lyme for Patients, Family, and Friends

Category:

Activism, Lyme, Testing, Treatment