Archive for the ‘Lyme’ Category

STEP RIGHT UP: Get Your Lyme Vaccine Here! (And Booster After Booster)

https://www.change.org/p/the-us-senate-calling-for-a-congressional-investigation-of-the-cdc-idsa-and-aldf/

STEP RIGHT UP… Get your Lyme vaccine here! (And booster after booster)

Carl Tuttle

Hudson, NH, United States

JAN 6, 2023 — 

Facts you may not know…

The FDA fast tracked Valneva’s Lyme disease vaccine in 2017 (Now purchased by Pfizer) which is based on outer surface protein A (OspA) of the Borrelia spirochete. LYMErix, the previous vaccine (OspA based as well) was pulled from the market with the manufacturer claiming poor sales.

A class action lawsuit:

“The people who have contacted us were, prior to vaccination with LYMErix, healthy, active and energetic. Indeed, the very reason they sought the LYMErix vaccine was their desire to preserve their healthy, active lifestyle. However, what they experienced was a dramatic degradation of their health and quality of life. As will be described below, these previously healthy individuals are now afflicted with painful, at times debilitating arthritic symptoms, including joint pain and swelling, as well as extremely severe Lyme-disease-like symptoms which have persisted to this day.”

To my knowledge, there were no studies to determine why this class of people experienced serious reactions to OspA based LYMErix. And we are to believe Pfizer will bring a “safe and effective” product to market? A company that paid the highest fine for health care fraud:

Justice Department Announces Largest Health Care Fraud Settlement in Its History

Pfizer to Pay $2.3 Billion for Fraudulent Marketing (Wednesday, September 2, 2009)

https://www.justice.gov/opa/pr/justice-department-announces-largest-health-care-fraud-settlement-its-history

A chronic relapsing seronegative disease does not fit the vaccine model so deny the chronically infected and your patents for vaccines and diagnostic technology continue to reap patent royalties as evidence of persistent infection (following the one-size-fits-all IDSA mandated treatment protocol) must be concealed/ignored at all costs.

In the interest of time I have shortened the evidence to five points below with most reference links taken from the NH COMMISSION TO STUDY TESTING FOR LYME AND OTHER TICK-BORNE DISEASES of which I was a member appointed by Governor Chris Sununu:

1. Barbara Johnson of the CDC put Advanced Laboratory Services out of business after the lab was reporting 80% positive culture results. If contamination was an issue as Johnson claimed,[1] why didn’t the CDC work with Advanced Laboratory Services to correct the problem? Culture is the gold standard for definitive diagnosis of bacterial and fungal infections worldwide but when it threatens the existing paradigm suddenly it becomes “not particularly useful.” Johnson by the way filed her own patent  [2] a year earlier for the detection, diagnosis and/or treatment of Lyme disease.

2. Dr. Sin Lee had been working with the CDC on a project to develop proficiency testing for his DNA sequencing-based tests for Lyme Borreliosis (Approved by the New York Dept. of Health) When Dr. Lee reported a case of chronic [3] Lyme through Sanger sequencing suddenly all communication stopped. A positive DNA test is irrefutable evidence of active infection.

3. The CDC refuses to recognize the mountain of publications identifying persistent infection after extensive antibiotic treatment. A chronic relapsing seronegative disease should have set off a red flag but its misclassification as a simple “nuisance disease” has left hundreds of thousands if not millions worldwide in a debilitated state.

4. The CDC refuses to recognize the disabling stage of Lyme disease as reported by the Lyme patient population worldwide because it contradicts the CDC 30yr Official Narrative; “Lyme is hard to catch and easily treated with 2-4wks of antibiotics.” Social Security disability compensation is denied leaving patients to fend for themselves.

5. Serology (Western blot) was manipulated to facilitate vaccine development. The two most significant bands, 31 (Outer surface protein A) and band 34 (Outer surface protein B) of the spirochete were removed as those who were vaccinated would test positive. Humans do not produce antibodies to Lyme disease for 4-6 weeks after a tick bite so serology has always been the wrong diagnostic tool but absolutely essential to deceptively prove vaccine efficacy.

Patent royalties and pharmaceutical profits [4] over lifesaving care.

Unimaginable pain and suffering for the sake of a vaccine while our public health officials ignore the evidence that we are dealing with an antibiotic resistant/tolerant superbug.

Where is the outrage???

Carl Tuttle
Hudson, NH

To TBDWG: “The CDC has propagated a false Lyme disease narrative”
https://www.lymedisease.org/tuttle-tbdwg-false-narrative/

Re: Lyme borreliosis: diagnosis and management (Published letter to the editor of the BMJ)
https://www.bmj.com/content/369/bmj.m1041/rr-1

Additional References
[1] Assessment of New Culture Method for Detection of Borrelia Species from Serum of Lyme Disease Patients

Barbara J. B. Johnson, Mark A. Pilgard, and Theresa M. Russell

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957795/

[2] COMPOSITIONS AND METHODS RELATING TO LYME DISEASE

Johnson Patent

https://patents.google.com/patent/WO2013110026A1/en?oq=ininventor:%22Barbara+J.B.+JOHNSON%22

[3] Lyme disease caused by Borrelia burgdorferi with two homeologous 16S rRNA genes: a case report

https://pubmed.ncbi.nlm.nih.gov/27186082/

[4] Valneva Receives FDA Fast Track Designation for its Lyme Disease Vaccine Candidate VLA15

https://valneva.com/wp-content/uploads/2019/06/2017_07_24_VLA_Lyme_FDA_Fast_track_PR_EN.pdf

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**Comment**

The same fraudulent testing, denial of life saving treatments, and patents on virtually every aspect of the disease in Lymeland, has also been seen with COVID, and has served as a clear worldwide example of collusion, fraud, and malfeasance perpetrated by corrupt government agencies, research institutions, mainstream medicine & media, and Big Pharma.

Category:

Activism, Lyme, vaccines

Lyme Arthritis Symptoms In Young Child Emerge Years After Tick Bite

https://danielcameronmd.com/lyme-arthritis-symptoms-child-years-after-tick-bite/

LYME ARTHRITIS SYMPTOMS IN YOUNG CHILD EMERGE YEARS AFTER TICK BITE

lyme-arthritis-children

Symptoms of Lyme disease may not present immediately following a tick bite. As this case report highlights, taking a thorough medical and travel history can be crucial in diagnosing and treating the illness.

By Dr. Daniel Cameron

In their article, “Ten-year-old Omani Girl with Lyme Arthritis,” Mughaizwi and colleagues describe a young child who had lived in the United States for 5 years before moving to Oman.¹ One year after her return to Oman, she developed symptoms of Lyme arthritis.

“We report a 10-year-old girl who presented with acute arthritis of the left knee, which was confirmed as Lyme arthritis by serology and molecular assay,” the authors wrote.

The patient had lived in upstate New York for several years and recalled having 2 tick bites. The bites occurred 2-3 years prior to her onset of symptoms.

One year after returning to Oman, the young child began experiencing pain and swelling in her left knee, which worsened over the course of a week. She reportedly had no other physical complaints or joint pain.

“Our patient gave a history of tick bites at least a year prior to her current presentation.”

An examination “revealed marked left knee swelling, mildly tender and warm to touch, extending 2 cm above and below the knee joint,” the authors wrote. Additionally, “There was mild erythema at the superolateral aspect of the joint.”

After MRI test results showed a “large knee joint effusion with diffuse thickening of the synovium,” the patient underwent a knee joint aspiration, which quickly improved knee mobility.

The child, initially treated for septic arthritis, was eventually diagnosed with Lyme arthritis based on her history of tick bites.

Further testing revealed she was positive for Lyme disease by ELISA and PCR. “Polymerase chain reaction (PCR) identified Borrelia burgdorferi in the joint fluid,” the authors wrote.

The young girl made a complete recovery following 4 weeks of treatment with IV cefuroxime.

The authors point out:

  • The stages of Lyme disease can overlap. As this case demonstrates, the late stage presented without any noticeable early-stage manifestations.
  • Symptoms may not appear until months after the tick bite. “Our patient gave a history of tick bites at least a year prior to her current presentation,” the authors explain.
  • Consultations should include a thorough history, including geographical exposure to Lyme endemic regions, which can be crucial in the early recognition and diagnosis of Lyme arthritis. “The patient lived in the US for five years and her symptoms developed about a year after her return to Oman… This case indicates the need to suspect Lyme disease in patients presenting with compatible symptoms and a history of recent travel to endemic regions,” the authors wrote.

How do you distinguish Lyme arthritis from septic arthritis?

Related Articles:

Diagnosing Lyme arthritis of the hip in children

Lyme arthritis in children can present throughout the year

Will steroid injections help children with Lyme arthritis of the knee?

References:
  1. Al Mughaizwi T, Al Rawahi H, Elamin N, Al Hinai Z, Al Muharrmi Z, Al Yazidi LS. Ten-year-old Omani Girl with Lyme Arthritis. Oman Med J. 2022 Nov 30;37(6):e446. doi: 10.5001/omj.2022.31. PMID: 36458239; PMCID: PMC9644041.

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For more:

Category:

Lyme, research

Senate Passes 2023 Omnibus Appropriations Bill

https://www.appropriations.senate.gov/imo/media/doc/Division%20H%20-%20LHHS%20Statement%20FY23.pdf

Senate Passes 2023 Omnibus Appropriations Bill

Below Article Update 12/23/2022: Following Senate passage by a 68-29 vote on Thursday, Dec. 22, the House passed an omnibus appropriations bill by a 221-205-1 vote on Friday, Dec. 23.  The President is expected to sign the measure.  To allow more time for full enactment of the omnibus, Congress passed a third continuing resolution for FY 2023 through Dec. 30, which the President signed on Friday, Dec. 23. 

Alert: Senate Releases 2023 Omnibus Appropriations Bill:  The Senate has just released the 2023 Omnibus Appropriations Bill.2023 Omnibus Appropriations Bill The Explanatory Statement includes, under Emerging & Zoonotic Infectious Diseases, $26M for Lyme, as well as much language on Lyme/VBD. It also incorporates activities in HR117-403 which includes Lyme language LDA provided to Congress.

The passage of an Omnibus through the end of FY23 is uncertain at this time.

**Comment**

Don’t expect much, if anything, to come of this.  Just more money going into the hands of The Cabal to do more of the same – line their pockets at the expense of sick patients. 

Category:

Activism, Lyme

Genomic Confirmation of Borrelia garinii, United States

https://wwwnc.cdc.gov/eid/article/29/1/22-0930_article

Volume 29, Number 1—January 2023
Natalie RudenkoComments to Author , Maryna Golovchenko, Ales Horak, Libor Grubhoffer, Emmanuel F. Mongodin1, Claire M. Fraser, Weigang Qiu, Benjamin J. Luft, Richard G. Morgan, Sherwood R. Casjens, and Steven E. Schutzer
 
 

Abstract

Lyme disease is a multisystem disorder primarily caused by Borrelia burgdorferi sensu lato. However, B. garinii, which has been identified on islands off the coast of Newfoundland and Labrador, Canada, is a cause of Lyme disease in Eurasia. We report isolation and whole-genome nucleotide sequencing of a B. garinii isolate from a cotton mouse (Peromyscus gossypinus) in South Carolina, USA. We identified a second B. garinii isolate from the same repository. Phylogenetic analysis does not associate these isolates with the previously described isolates of B. garinii from Canada.

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Important excerpt:

How and when B. garinii arrived in South Carolina remains unknown. There were no reported Lyme disease outbreaks in the southeastern United States in humans at the time the strains were deposited in the repository or during the subsequent 2 decades. This finding minimizes the urgency for an immediate new search for B. garinii in this region. Nonetheless, clinical vigilance for B. garinii in humans in this region seems warranted.

 

True to form, the CDC downplays the finding of a new strain which very well could explain why sick patients continue to be mis or undiagnosed due to faulty testing and strain diversity, which will never be picked up using current 2-tiered CDC testing because it doesn’t look for other strains.

But, truth be damned.  It just doesn’t matter to corrupt public health.

Category:

Lyme, research, Testing, Ticks

3 Reasons Lyme/MSIDS Patients Remain Sick: Dormancy/Persisters, Biofilm, Co-Infection

https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-019-3495-7

Metamorphoses of Lyme disease spirochetes: phenomenon of Borrelia persisters

Parasites & Vectors volume 12, Article number: 237 (2019) Cite this article

Abstract

The survival of spirochetes from the Borrelia burgdorferi (sensu lato) complex in a hostile environment is achieved by the regulation of differential gene expression in response to changes in temperature, salts, nutrient content, acidity fluctuation, multiple host or vector dependent factors, and leads to the formation of dormant subpopulations of cells. From the other side, alterations in the level of gene expression in response to antibiotic pressure leads to the establishment of a persisters subpopulation. Both subpopulations represent the cells in different physiological states. “Dormancy” and “persistence” do share some similarities, e.g. both represent cells with low metabolic activity that can exist for extended periods without replication, both constitute populations with different gene expression profiles and both differ significantly from replicating forms of spirochetes. Persisters are elusive, present in low numbers, morphologically heterogeneous, multi-drug-tolerant cells that can change with the environment. The definition of “persisters” substituted the originally-used term “survivors”, referring to the small bacterial population of Staphylococcus that survived killing by penicillin. The phenomenon of persisters is present in almost all bacterial species; however, the reasons why Borrelia persisters form are poorly understood. Persisters can adopt varying sizes and shapes, changing from well-known forms to altered morphologies. They are capable of forming round bodies, L-form bacteria, microcolonies or biofilms-like aggregates, which remarkably change the response of Borrelia to hostile environments. Persisters remain viable despite aggressive antibiotic challenge and are able to reversibly convert into motile forms in a favorable growth environment. Persisters are present in significant numbers in biofilms, which has led to the explanation of biofilm tolerance to antibiotics. Considering that biofilms are associated with numerous chronic diseases through their resilient presence in the human body, it is not surprising that interest in persisting cells has consequently accelerated. Certain diseases caused by pathogenic bacteria (e.g. tuberculosis, syphilis or leprosy) are commonly chronic in nature and often recur despite antibiotic treatment. Three decades of basic and clinical research have not yet provided a definite answer to the question: is there a connection between persisting spirochetes and recurrence of Lyme disease in patients?

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287027/

The Emerging Role of Microbial Biofilm in Lyme Neuroborreliosis

Enea Gino Di Domenico,1,* Ilaria Cavallo,1 Valentina Bordignon,1 Giovanna D’Agosto,1 Martina Pontone,1 Elisabetta Trento,1 Maria Teresa Gallo,1 Grazia Prignano,1 Fulvia Pimpinelli,1 Luigi Toma,2 and Fabrizio Ensoli1
Author information Article notes Copyright and License information Disclaimer
 

Abstract

Lyme borreliosis (LB) is the most common tick-borne disease caused by the spirochete Borrelia burgdorferi in North America and Borrelia afzelii or Borrelia garinii in Europe and Asia, respectively. The infection affects multiple organ systems, including the skin, joints, and the nervous system. Lyme neuroborreliosis (LNB) is the most dangerous manifestation of Lyme disease, occurring in 10–15% of infected individuals. During the course of the infection, bacteria migrate through the host tissues altering the coagulation and fibrinolysis pathways and the immune response, reaching the central nervous system (CNS) within 2 weeks after the bite of an infected tick. The early treatment with oral antimicrobials is effective in the majority of patients with LNB. Nevertheless, persistent forms of LNB are relatively common, despite targeted antibiotic therapy. It has been observed that the antibiotic resistance and the reoccurrence of Lyme disease are associated with biofilm-like aggregates in B. burgdorferi, B. afzelii, and B. garinii, both in vitro and in vivo, allowing Borrelia spp. to resist to adverse environmental conditions. Indeed, the increased tolerance to antibiotics described in the persisting forms of Borrelia spp., is strongly reminiscent of biofilm growing bacteria, suggesting a possible role of biofilm aggregates in the development of the different manifestations of Lyme disease including LNB.

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https://www.fortunejournals.com/articles/serological-and-pcr-evidence-of-infection-in-105-patients-with-sppt.html

Serological and PCR evidence of Infection in 105 Patients with SPPT

Alexis Lacout1*, Marie Mas4, Michel Franck2, Véronique Perronne3, Julie Pajaud2, Pierre Yves Marcy5, Christian Perronne3

*Corresponding Author: Alexis Lacout, Centre de diagnostic ELSAN, Centre Médico–Chirurgical, 83 avenue Charles de Gaulle, 15000, Aurillac, France

Received: 11 December 2020; Accepted: 22 December 2020; Published: 05 January 2021

Citation: Alexis Lacout, Marie Mas, Michel Franck, Véronique Perronne, Julie Pajaud, Pierre Yves Marcy, Christian Perronne. Serological and PCR evidence of Infection in 105 Patients with SPPT. Archives of Microbiology & Immunology 5 (2021): 139-150.

Abstract

Introduction: The main aim of this study is to determine the nature of the exposure of patients presenting with polymorphic signs and symptoms to the parasite Babesia, through the study of serology. The secondary aim is to report the different serological or PCR results observed in these patients.

Material and methods: The following serologies were performed in all patients looking for: Babesia divergens, Borrelia, Bartonella, Coxiella burnetii, Anaplasma phagocytophilum. The following PCRs were performed looking for: Borrelia spp, Babesia spp, Bartonella (Bartonella spp, B. quintana, B. Henselae,) Coxiella spp, Anaplasma spp, Ehrlichia spp, Rickettsia spp, most often on several matrices (venous blood, capillary blood, urine and saliva).

Results: In this study, 105 patients were included, 62 females and 43 males, sex ratio F/M was 62/43 = 1.44; mean age was 45.5 year old (range; 5 years, 79 years old).

  • Of the 105 serologies for B. divergens, 41% were found to be positive.
  • Of the 104 serologies for Borrelia, 19.2% were found to be positive.
  • Of the 95 serologies for Anaplasma, 27.3% were found to be positive.

Borrelia spp, Babesia spp, Bartonella spp, Coxiella spp, Anaplasma spp, Ehrlichia spp, Rickettsia spp were found by using rtPCR.

Conclusion: Our study has shown that patients with SPPT/PTLDS, a syndrome close to fibromyalgia, could harbor several tick borne microorganisms. Microbiologic analyses should thus not be merely limited to Borrelia’s research alone.

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**Comment**

These relatively recent studies (within the past few years) reveal what Lyme literate doctors and their patients have been experiencing from the beginning.  They also reaffirm what many independent researchers have globally been writing about for years.  There are many other reasons patients remain ill as well but these three are biggies.

Yet, reality is best summed up by the following quote from the first study listed above:

Three decades of basic and clinical research have not yet provided a definite answer to the question: is there a connection between persisting spirochetes and recurrence of Lyme disease in patients?

Isn’t that sad?

The same, of course, can be said of biofilm and coinfections as well. Decades have gone by with no definitive answers because The Cabal doesn’t want the truth to be known. Why? Quite simple: a chronic, relapsing illness doesn’t fit their “vaccine” narrative which is the favored golden calf and cash cow of research institutions and our government, which have a cozy relationship with Big Pharma and Big Media.  This is quite convenient for all of them as they control all the messaging as well as threaten, censor, and ban doctors who dissent.

This has been blatantly exposed during the time of COVID but is nothing new.  Lymeland has been riddled with the exact same issues for 40 years.  Unfortunately, even well-meaning advocates and patients evidently can not see this and continue to demand more money and become giddy when they get it from the very agencies behind this debacle, who are incidentally profiting from it.

It’s a hot-mess for sure, but one thing is certain: we must stop playing into their hands by being ignorant or filled with “hopium,” a term I use to describe how hope can become a drug that stops you from thinking critically, logically, and honestly.

For more:

Category:

Anaplasmosis, Babesia, Bartonella, Biofilm, Ehrlichiosis, Lyme, research, Rickettsia, Testing