Archive for the ‘Lyme’ Category

Post-Treatment Lyme Disease Syndrome & Language Fluency Deficits

https://academic.oup.com/acn/advance-article-abstract/doi/10.1093/arclin/acac095/6955887?

Language Fluency Deficits in Post-treatment Lyme Disease Syndrome

Archives of Clinical Neuropsychology, acac095, https://doi.org/10.1093/arclin/acac095
Published:  22 December 2022

 

Abstract
Objective

Recent neurocognitive studies of patients with post-treatment Lyme disease syndrome (PTLDS) find consistent deficits in memory and processing speed. Language fluency deficits are observed as well but may be secondary to poor memory and slowing rather than an independent deficit.

Method

This study performed a secondary analysis of data presented previously, including individuals with PTLDS and comparison samples of healthy volunteers (HC) and patients with major depressive disorder (MDD), to determine if language fluency deficits could be accounted for by poor performance in these other neurocognitive domains.

Results

Basic verbal abilities, memory, and processing speed were all significantly associated with fluency performance. MDD patients’ fluency deficits relative to HC were accounted for by these covariates. However, PTLDS patients’ poorer fluency performance relative to both other groups was not.

Lyme Literate Docs Needed in Pennsylvania

https://www.lymedisease.org/ilads-pa-lyme-conf-march-24-25/

Inform your doctors about ILADS/PA Lyme conference March 24-25

A Message from PA Lyme Resource Network

We need your help!

Pennsylvania urgently needs more Lyme-literate healthcare practitioners.  We’ve been the #1 state for instances of Lyme disease and tick-borne illness for seven consecutive years, yet we’re losing more LLMDs than we’re gaining.

Working to change that, we’re partnering with ILADS to bring an important Lyme & Tick-Borne Disease Medical Conference to Hershey, PA on March 24-25.

The more doctors and medical practitioners we can bring to the conference, the better for our Pennsylvania communities. This is why we’re asking you to personally invite your primary care practitioner and any other doctors you can reach.

Ways to take action:

About ILADS

About PA Lyme Resources Network

Patent Royalties & Pharma Profit Over Lifesaving Care

https://www.change.org/p/the-us-senate-calling-for-a-congressional-investigation-of-the-cdc-idsa-and-aldf

Patent royalties and pharmaceutical profits over lifesaving care?

Carl Tuttle

Hudson, NH, United States
Dr. Raymon Dattwyler 

JAN 8, 2023 — 

Please see the following letter addressed to Dr. Raymond Dattwyler who owns 24 patents for Lyme disease that include diagnostic testing and vaccines both live bacteria and oral.

Gomes-Solecki co-owns 17 patents with Dattwyler.

To view these patents, go to…

Patent Public Search Basic
https://ppubs.uspto.gov/pubwebapp/static/pages/ppubsbasic.html

———- Original Message ———-

From: CARL TUTTLE <runagain@comcast.net>
To: “Raymond_Dattwyler@nymc.edu” <Raymond_Dattwyler@nymc.edu>
Cc: “npjvaccines@nature.com” <npjvaccines@nature.com>, “abarrett@utmb.edu” <abarrett@utmb.edu>, “R.W.Titball@exeter.ac.uk” <R.W.Titball@exeter.ac.uk>, “mgomesso@uthsc.edu” <mgomesso@uthsc.edu>
Date: 01/06/2023 2:46 PM
Subject: The year that shaped the outcome of the OspA vaccine for human Lyme disease

npj Vaccines Jan 2022

The year that shaped the outcome of the OspA vaccine for human Lyme disease
https://www.nature.com/articles/s41541-022-00429-5

Raymond J. Dattwyler & Maria Gomes-Solecki

Department of Microbiology and Immunology
New York Medical College
Valhalla, NY
Raymond J. Dattwyler, Corresponding Author

Dear Dr. Dattwyler,

I read your manuscript with great interest as you call attention to a treatment-resistant Lyme arthritis with “no evidence of DNA” found in the joints of patients after antibiotic treatment.

For some strange reason however, I could not find the following 1995 publication within your paper identifying treatment-resistant neuroborreliosis:

European Neurology 1995

Seronegative Chronic Relapsing Neuroborreliosis
https://www.karger.com/Article/Abstract/117104

Lawrence C., Lipton R.B., Lowy F.D., Coyle P.K.d

Abstract

We report an unusual patient with evidence of Borrelia burgdorferi infection who experienced repeated neurologic relapses despite aggressive antibiotic therapy. Each course of therapy was associated with a Jarisch-Herxheimer-like reaction. Although the patient never had detectable free antibodies to B. burgdorferi in serum or spinal fluid, the CSF was positive on multiple occasions for complexed anti-B. burgdorferi antibodies, B. burgdorferi nucleic acids and free antigen.

____________________________________________

In fact, Dr. Dattwyler there seems to be a great deal of “treatment-resistant” evidence published in multiple journals over the past three decades:

Peer Reviewed Evidence of Persistence of Lyme Disease Spirochete Borrelia burgdorferi and Tick-Borne Diseases (700 References)
https://www.dropbox.com/s/n09sk90eo6xz7ua/700%20articles%20LYME%20EvidenceofPersistence-V2.pdf?dl=0

So that brings me to the reason for this email…

Question:

Does a chronic relapsing seronegative disease fit the vaccine model? If not, would that, in and of itself, be the hidden reason for denying chronic (treatment-resistant) Lyme disease for almost three decades?  In other words, patent royalties and pharmaceutical profits over lifesaving care?

A response to this inquiry is requested.

Carl Tuttle
Hudson, NH

Cc: Alan D.T. Barrett, PhD Editor-in-Chief
Rick Titball, PhD, DSc, Deputy Editor

Letter to the Editor of the BMJ published June 2020
https://www.bmj.com/content/369/bmj.m1041/rr-1

________________

**Comment**

We can thank Tuttle for doggedly pursuing fraud and corruption that is truly shackling thousands of sick patients to an obsolete model that is neither scientific nor logical.

BTW: the corruption continues:

What’s Preventing Your Recovery From Lyme Disease?

https://www.lymedisease.org/maderis-whats-preventing-recovery/

What’s preventing your recovery from Lyme disease?

By Todd Maderis, ND

Jan. 3, 2023

As we begin a new year, I have spent time reflecting on what is preventing many people with complex chronic illnesses, including Lyme disease, from getting better.

If you’re one of the many people struggling to recover from chronic illness, I offer some thoughts for your consideration.

So, what is preventing people with chronic illnesses from getting better?

Access to physicians with experience treating Lyme disease

According to LymeDisease.org’s patient-driven research platform, MyLymeData, a significant obstacle to an accurate diagnosis is patient access to care by a healthcare provider experienced in Lyme disease and associated infections.

Almost 50% of respondents in the MyLymeData registry reported they saw over seven physicians before being diagnosed with Lyme disease. Treatments for Lyme disease are more effective the earlier they are implemented. Unfortunately, for 73% of respondents, it took over a year for a correct diagnosis.

In a MyLymeData survey of Lyme-treating doctors, physicians report the top three reasons patients receive a delayed diagnosis of Lyme disease are inadequate physician education about tick-borne diseases, false-negative lab results, and a prior misdiagnosis.

Barriers that contribute to a delayed or accurate diagnosis include poor insurance coverage for Lyme disease, healthcare costs, and a limited number of healthcare providers that diagnose and treat persistent Lyme disease.

As cases of Lyme disease rise in the United States and research studies demonstrate a clear need for improved diagnostics and treatment, we will likely see increased recognition and awareness by healthcare agencies and improved insurance coverage.

Where do people with chronic illnesses turn when they don’t have access to quality care?

When people do not have access to a physician experienced in treating Lyme disease, they often turn to online patient support groups for guidance. While these groups can be valuable sources of information and provide emotional support, the suggestions offered by one person may not be what is best for another.

Has the person seeking help been adequately tested for Lyme disease and all associated infections by a reputable tick-borne infection testing laboratory? Do they have additional variables undermining their health, such as high environmental toxin levels or immune system dysregulation, that must be addressed? What is the correct order of treatment?

Physicians treating complex chronic illnesses are challenged to identify all the possible underlying causes of a patient’s symptoms and implement effective treatment strategies. It would be difficult for a member of a support group who is not a physician to know what is best for another person.

Obtaining an accurate diagnosis

If you do not have a map, how do you get to where you want to go? Recovering from illness works the same way. An effective treatment strategy is only as good as the accuracy of the diagnosis. Nuances associated with Lyme disease lab tests create a challenge to getting an accurate diagnosis.

I only rely on reputable Lyme specialty laboratories to make a diagnosis. Testing for chronic viral infections, mold illness, heavy metal toxicity, digestive disorders, and more presents the same obstacle.

Conventional labs like LabCorp and Quest are fine for general markers like blood counts, chemistry panels, and thyroid hormones, but specialized labs need to be used for all the conditions mentioned above. Even within specialized laboratories, some provide more accurate data than others.

The labs that provide me (and my patients) with the best “map” change over time based on advances in testing and my clinical observations. If you tested for tick-borne infections or the above conditions over a year ago, the tests should be repeated because testing has improved. It’s essential to know the current status of the results.

Receiving effective treatments

If you have access to care from a physician experienced in treating Lyme disease and have identified all the underlying causes(s) of your symptoms, the next hurdle is employing effective treatments.

With correct diagnoses, the therapies need to be specific and intentional. Patients tell me they have been prescribed successive treatments for a diagnosis when each treatment did not work. This is like throwing the proverbial spaghetti at the wall and hoping it sticks. Of course, identifying efficacious therapies is challenging, but having a clear direction and using proven treatments is an effective strategy.

Losing hope of healing

People lose hope they will recover from their illness the longer they remain sick. It is disheartening to see patients feeling hopeless because they have been sick for years, have seen many doctors, and have tried dozens of treatments. Hopelessness results from one (or more) of the above reasons.

Some patients I see are mentally unable to move forward once they have an accurate diagnosis and access to effective treatments. It could be that they don’t believe they will ever recover because they have been down multiple dead-end roads of treatment. Some people are traumatized by their illness and have fear or anxiety about an adverse reaction to another treatment. Others do not have the support of their family or partners, possibly due to the invisible illness that is Lyme disease. As the saying goes, “if nothing changes, nothing changes.”

As we begin  a new year, I encourage you to reflect upon your health to consider what prevents you from fully recovering from your chronic illness. The general challenges I outlined can serve as an algorithm to help you identify the obstacles to healing so you can take action that moves you closer to optimal health.

Dr. Todd Maderis is Founder and Medical Director of Marin Natural Medicine Clinic in Larkspur, CA. He blogs at DrToddMaderis.com.

_________________

For more:

Are Parasites Making You Sick? Here’s Everything You Need to Know If You Have Lyme/MSIDS

https://rawlsmd.com/health-articles/are-parasites-making-you-sick-heres-everything-you-need-to-know-if-you-have-lyme

Are Parasites Making You Sick? Here’s Everything You Need to Know If You Have Lyme

by Stephanie Eckelkamp
Posted 1/5/22

Chances are you’ve heard someone boast the benefits — or even the necessity — of doing a parasite cleanse. They’ve probably listed some talking points about how parasites are more common than you think, that they’re driving your mystery symptoms, or that they tend to crop up in people with chronic ailments like Lyme disease. It’s enough to make anyone feel a little, well, squirmy. But how realistic is it that you’re truly playing unintentional host or that getting rid of these invaders is your secret to wellness?

According to Dr. Bill Rawls, MD, medical director of RawlsMD and Vital Plan, the logic doesn’t totally stack up. While it’s always possible you could have a parasite — depending on your living conditions, travel history, and eating and cooking habits — he is doubtful that they’re wreaking too much havoc on your health if you live in the United States or another high-income country.

Below, we cover the basics of parasites, who could be at greater risk for complications, and some basic preventative measures.

What are Parasites, Anyway?

“All living organisms that depend on a host are parasites. So technically all the microbes (bacteria, viruses, protozoa) in our bodies are parasites — but generally, what people refer to when they say parasites are worms,” says Dr. Rawls. (Think: roundworm, hookworm, flatworm.)

While microbes can replicate by cell division (or, in the case of viruses, by commandeering your own body’s cells), parasitic worms (or “helminths”) are multicellular organisms that reproduce a bit differently. They typically enter the body as eggs or larvae via contaminated water, soil, or food. Then, they make their way to your intestines, where they attach and suck blood and nutrients from your body — which could contribute to issues like anemia, nutrient deficiencies, gastrointestinal distress, fatigue, and weight loss.

Eventually, these parasitic worms reproduce sexually or asexually and shed eggs. Thankfully, the eggs pass through your stool and hatch outside the body — so you won’t continue accumulating more worms in your system.

Even though worms won’t multiply inside of you, some species can survive in the body for a couple of years, so it’s important to get treated if you suspect something is amiss. Still, having worms doesn’t always mean you’ll have negative health consequences: “Unless you’ve got a significant load of parasites, you may not have much in the way of symptoms at all,” says Dr. Rawls. “And the only way you’ll have a high parasitic load is if you continue ingesting new eggs or larvae from a contaminated source, which is unlikely in the U.S. and other developed countries.”

Beyond worms, three notable intestinal parasites in the protozoa category are giardiacryptosporidium (or “crypto”), and toxoplasmosis. Giardia and crypto are more common in the U.S. and are typically contracted from fecal-contaminated lakes or streams. Unlike worms, these do have the ability to multiply in the body. Some individuals may experience no symptoms at all, but for others, the main symptoms include diarrhea, stomach cramps, vomiting, and dehydration. Often, symptoms clear up on their own in a few weeks, but if not, medications are available.

young adult woman at home, holding hands to stomach in discomfort

Toxoplasmosis affects various bodily tissues. It’s estimated to infect 11% of the population over age six, and it’s often contracted by eating undercooked, contaminated meat or shellfish. Toxoplasmosis may cause flu-like symptoms that resolve in weeks to months, or you might have no symptoms. Either way, it remains in the body inactive and could be reactivated (potentially becoming problematic) if a person becomes immunosuppressed.

Who’s Most Likely to Contract Parasites?

You’re far more likely to get parasitic worms if you live in or visit an economically-developing country. Helminths are typically transmitted via fecal contamination of food and drinking water or from walking barefoot on fecal-contaminated soil. This is more common in places without modern toilets or sewage systems.

For example: “If you live in a country where your outhouse is near your drinking supply or where you grow your food, there’s a good chance that some of those eggs or larvae will get into things you’re ingesting,” says Dr. Rawls. “You could also be at risk of reinfecting yourself.”

In the U.S., you could also pick up parasites from eating undercooked meat or fish and handling contaminated cutting boards or utensils without properly washing your hands. You may also be exposed to them from eating contaminated produce like leafy greens (although, these are more likely to be contaminated with a pathogen like E. coli or norovirus). You may also contract giardia or cryptosporidium from ingesting contaminated water from lakes, ponds, or rivers.

Pets could be a sneaky source of parasites, too. Puppies and kittens are more likely to be infected with roundworms, hookworms, or giardia. Cats who spend time outdoors and consume infected rodents or birds can contract toxoplasmosis and pass it in their feces, so changing litter boxes poses a potential risk for exposure. Pregnant individuals need to be particularly cautious about avoiding toxoplasmosis exposure early in pregnancy because it has been linked to miscarriages, stillbirths, and health problems for the baby.

That said, “the research does not show that people in the U.S. have heavy parasite loads,” says Dr. Rawls. “Everyone’s situation is different, and maybe people are picking stuff up here and there, but that’s not average.” Given our good sanitation practices, treated water supplies, and monitoring of food products by governmental agencies, serious parasitic infections are rare.

Are You More Likely to Get a Parasite if You Have Lyme?

The state of your immune health does have an impact on your ability to clear parasites and keep symptoms at bay. “The research in developing countries shows that the biggest parasite loads are found in people with compromised immune health,” says Dr. Rawls.

Additionally, if you have a condition like HIV/AIDS or cancer, or you’re taking certain immunosuppressive drugs, you may be at a greater risk for more severe complications from a parasitic infection, warns the Centers for Disease Control and Prevention (CDC). Pregnancy or those young or old in age can also be states where the body is considered immunosuppressed, and treating parasitic infections with medications is much more likely to be necessary.

What does this mean for people with chronic Lyme disease? It’s unclear. Lyme patients may be less able to tolerate and neutralize parasites than their Lyme-free counterparts, says Dr. Rawls. But the research just isn’t there to show that people with Lyme end up with heavy parasite loads. So it’s difficult to say with certainty if Lyme poses an increased risk of parasites or if parasites are actively inhibiting your ability to heal from Lyme.

What Steps Can You Take to Protect Yourself from Parasites?

If you have a strong immune system, eat clean food, and filter your water, the chances that you’re being exposed to big parasite loads are pretty slim, says Dr. Rawls. Here are some basic practices to keep yourself safe (spoiler: you may not want to jump right to an intense parasite cleanse you find on the internet):

1. Practice Good Hygiene for You and Your Pet.

Wash your hands regularly, especially after touching soil, using the bathroom, touching animals, or disposing of animal feces. Keep your pets current on dewormer treatments, too. They should ideally be on a monthly, year-round preventative product for intestinal parasites and heartworm.

2. Follow Safe Food Prep Practices.

Thoroughly wash fruits and vegetables and cook meat to the safe minimum internal temperature. Avoid consuming undercooked meat and fish, particularly if you’re immunocompromised.

3.Avoid Ingesting Water from Lakes, Ponds, or Streams.

This is a must for curbing your risk of giardia and cryptosporidium. Always bring your own filtered water and be careful not to ingest water while swimming.

4. Protect Yourself in High-Risk Areas.

Contact your local health department before traveling to another country for information on the parasites and diseases you may encounter, and see if prophylactic medication is recommended. If you’re going somewhere without modern sewage systems, only drink bottled water.

5. Take Steps to Support Immune Health.

Any steps you can take to support overall health — getting enough sleep, moving your body regularly, eating a nutrient-dense diet loaded with colorful veggies, minimizing stress — will support your body’s immune system in neutralizing foreign invaders, parasites or otherwise.

6. Regularly Consume Gentle Herbs.

Several herbs with gentle, antiparasitic properties are safe to take on a regular basis, says Dr. Rawls. GarlicandrographisJapanese knotweedcat’s claw — all of these have been traditionally used for their anti-helminth properties,” he says. “They help create an environment that makes it more difficult for parasites to exist or reproduce.” The good news: These are all beneficial herbs for suppressing Lyme-related microbes, too, and they’re commonly found in herbal therapy protocols.

7. Be Cautious with Herbal Parasite Protocols.

Often, the parasite cleanses you read about online involve the classic combo of clove, wormwood, and black walnut, but using these without medical supervision is not advised. “These are strong enough that I don’t use them routinely,” says Dr. Rawls. “Clove can be irritating to the gut, long-term use of wormwood can cause neurological issues, and black walnut can make you feel terrible.”

Other herbal products that have gained popularity for their potential antiparasitic properties include papaya seeds and Mimosa pudica — but their safety and optimal dose is still unclear. Papaya seeds were shown in a small 2007 study to effectively clear intestinal parasites from a group of Nigerian children, but the research pretty much stops there. Studies are also scant on Mimosa pudica. While it’s been traditionally used in Ayurvedic medicine to manage diarrhea and infections, it contains “anti-fertility” properties, so it should be avoided if you’re pregnant or trying to become pregnant.

What Should You Do If You Suspect a Parasite?

Symptoms will vary depending on the parasite and your baseline level of health, but contact your doctor if you experience diarrhea, abdominal pain, bloating, rashes, itching around the rectum, fatigue, weight loss, or if you notice a worm in your stool. Tell them if you’ve consumed undercooked meat or fish, been in contact with potentially contaminated water, or if you’ve taken a trip abroad within the past two years (since parasites may take time to trigger symptoms).

Your doctor will likely order an ova and parasite test (O&P), which looks for parasitic worms and protozoa. For this test, the CDC recommends at least three stool samples, collected on separate days, be examined. Testing for toxoplasmosis, on the other hand, can be a bit trickier and may involve testing blood or cerebrospinal fluid for antibodies or the presence of parasites. If you do have a parasite, there are a variety of medications that should alleviate your infection.

If you’re tempted to try a natural approach with herbs such as clove, wormwood, black walnut, papaya seeds, or Mimosa pudica, be sure to do so in conjunction with a doctor familiar with natural remedies for parasites.

Bottom Line.

Parasitic infections are rare in high-income countries like the U.S. If you do contract something, there’s a good chance your body might clear it on its own; but if you have troubling symptoms, contact your doctor.

While there’s no clear connection between Lyme disease and an increased risk or severity of parasitic infections, there are ways to protect yourself if you’re worried — from healthy food prep to immune-supporting lifestyle habits to gentle, antiparasitic herbs. Just avoid trying popular “quick fixes” on your own, which could wind up doing more harm than good.

Dr. Rawls is a physician who overcame Lyme disease through natural herbal therapy. You can learn more about Lyme disease in Dr. Rawls’ new best selling book, Unlocking Lyme. You can also learn about Dr. Rawls’ personal journey in overcoming Lyme disease and fibromyalgia in his popular blog post, My Chronic Lyme Journey.

REFERENCES
1. Ahmad H, Sehgal S, Mishra A, Gupta R. Mimosa pudica L. (Laajvanti): An overview. Pharmacogn Rev. 2012;6(12):115-124. doi:10.4103/0973-7847.99945
2. Ascariasis. Cleveland Clinic website. ​​https://my.clevelandclinic.org/health/diseases/14071-ascariasis
3. Cryptosporidium: General Information for People With Weakened Immune Systems. Centers for Disease Control and Prevention website. 
https://www.cdc.gov/parasites/crypto/gen_info/infect_ic.html
4. Cryptosporidium. Centers for Disease Control and Prevention website. https://www.cdc.gov/parasites/crypto/index.html
5. Do Papaya Seeds Get Rid of Intestinal Parasites? Cleveland Clinic website. https://health.clevelandclinic.org/papaya-seeds-parasite-cleanse/
6. Giardia. Centers for Disease Control and Prevention website. https://www.cdc.gov/parasites/giardia/index.html
7. Lettuce, Other Leafy Greens, and Food Safety. Centers for Disease Control and Prevention website. https://www.cdc.gov/foodsafety/communication/leafy-greens.html
8. Okeniyi JA, Ogunlesi TA, Oyelami OA, Adeyemi LA. Effectiveness of dried Carica papaya seeds against human intestinal parasitosis: a pilot study. J Med Food. 2007;10(1):194-196. doi:10.1089/jmf.2005.065
9. Parasites: Diagnosis of Parasitic Diseases. Centers for Disease Control and Prevention website. https://www.cdc.gov/parasites/references_resources/diagnosis.html
10. Parasites: Travelers. Centers for Disease Control and Prevention website. https://www.cdc.gov/parasites/travelers.html
11. Safe Minimum Internal Temperature Chart. USDA Food Safety and Inspection Service website. https://www.fsis.usda.gov/food-safety/safe-food-handling-and-preparation/food-safety-basics/safe-temperature-chart
12. Toxoplasmosis. Centers for Disease Control and Prevention website. https://www.cdc.gov/parasites/toxoplasmosis/
13. Transmission of Parasitic Diseases. Centers for Disease Control and Prevention website.
https://www.cdc.gov/parasites/transmission/index.html
14. Worms in humans. The National Health Service website. https://www.nhs.uk/conditions/worms-in-humans/
15. Ova and Parasite Test. MedlinePlus website. https://medlineplus.gov/lab-tests/ova-and-parasite-test/
_________________
**Comment**
I must disagree with this article.  I believe parasites are much more common than believed.  The fact is, they are rarely reported.  Big difference.
Lyme discoverer, Willy Burgdorfer, wrote of finding nematodes in tick guts way back in 1984, and in 2014 University of New Haven researcher, Eva Sapi, found 22% of nymphs and 30% of adult Ixodesticks carried nematodes.
So, technically you can be infected with worms and other parasites directly from a tick bite – and perhaps from other bugs as well.
But, I do agree that third world countries have far more experience with parasites than the U.S.  Ideally, we could all work with a physician from one of these countries as they are walking encyclopedias about parasites.
So, what to do?
Like nearly everything else with Lyme/MSIDS we are Guinea Pigs and we simply need to experiment.  The results will speak for themselves.  I highly recommend you talk about this issue with your LLMD who undoubtedly will have experience and/or opinions about this.  I do caution patients because herxing from parasite die-off can be brutal – even life-threatening so you don’t want to be doing this on your own.
For more:

Pathologist Alan MacDonald has done it again.

He found three strains of borrelia living in parasitic nematode worms, worm eggs, or larvae in the brain tissue of 19 autopsies.  

MacDonald states that both worms and borrelia can cause devastating brain damage and that

“while patients are wrongly declared free of Lyme and other tick-borne infections, in reality, too often they contract serious neurodegenerative diseases which can kill them.”