Author Archive

Lyme Disease Increases Risk for Multiple Gynecological Conditions

https://www.medrxiv.org/content/10.1101/2025.03.03.25323258v1

Lyme disease increases risk for multiple gynecological conditions

Paige S. Hansen Colburn, Grace Blacker, Sarah Galloway, Qingying Feng, Prasanna S. Padmanabham, Guido Pisani, Brandon T. Lee, Grace Loeser, Monika W Perez, Kunzan Liu, Jade Kuan, Emelia von Saltza, Satu Strausz, Lisa M. Mattei, Sophie VanderWeele, George R. Nahass, Amie Kitjasateanphun,  Rangarajan Bharadwaj, Hari-Hara SK Potula, Maia Atzmon Shoham, Finngen, Victoria L. Mascetti, Eric Gars, Hanna M Ollila, Kaylon L. Bruner-Tran, Irving Weissman,  Sixian You, Beth Pollack, Linda Griffith, Nasa Sinnott-Armstrong,  Michal Caspi Tal
doi: https://doi.org/10.1101/2025.03.03.25323258

This article is a preprint and has not been peer-reviewed [what does this mean?]. It reports new medical research that has yet to be evaluated and so should not be used to guide clinical practice.

Abstract

Lyme disease (LD) is an illness caused by the spirochete Borrelia burgdorferi (B. burgdorferi). Borrelia is known to disseminate through organs, including the skin, joints, spinal cord, bladder, and heart, leading to Lyme arthritis, neuroborreliosis, and Lyme carditis. While previous studies have investigated the impact of LD on pregnancy in both mice and humans and have found the presence of B. burgdorferi in the uterus of mice, we studied the impact of LD on the non-pregnant female reproductive tract. We use a mouse model for LD and find an ongoing and severe infection of the reproductive tract of female mice, which persists up to 15-months post-inoculation. This infection results in uterine glandular cysts and endometrial hyperplasia as well as vaginal epithelial thickening, polymorphonuclear and mononuclear cell epithelial infiltration, and epithelial desquamation into the vaginal lumen. Strikingly, we find that age has an impact on the extent of gynecologic pathology such that aged female mice (1-year old) that are reproductively senescent have more gynecologic pathology with infection compared to young mice (15-weeks old) when infected for the same length of time. Using large-scale electronic healthcare record data, we report that LD additionally results in increased infection-associated risk of:

  1. menorrhagia (1.5-fold)
  2. miscarriage (1.62-fold)
  3. uterine fibroids (1.42-fold)
  4. endometriosis (1.93-fold)

Underreporting of gynecological outcomes is pervasive throughout many different infectious diseases, and LD-associated gynecological pathologies may have been similarly underappreciated in the field. This work suggests that further study of the female reproductive tract and the effects of B. burgdorferi infection therein will help clarify and expand the knowledge of myriad LD outcomes.

For more:

Category:

Lyme, research, Transmission

Society Reaches ‘Peak Insanity’: Trillions Invested in mRNA ‘Vaccines’ & Therapies

https://jamesroguski.substack.com/p/mrna-products-in-the-development?

mRNA Products in the Development Pipeline

Trillions of dollars are being invested in developing hundreds of mRNA “vaccines” and other mRNA-based “therapies.” Our society has reached “Peak Insanity.”

 
James Roguski
Mar 06, 2025
 
 

Moderna CEO Wants mRNA Factory on Every Continent

Moderna has dozens of mRNA “vaccines,” and cancer therapies, in their development pipeline:

Moderna’s dozens of mRNA ‘vaccines’ in development:

  1. mRNA-1010 (Flu) CLINICAL TRIAL NCT05606965

  2. mRNA-1011 (Flu) CLINICAL TRIAL NCT05827068

  3. mRNA-1012 (Flu) CLINICAL TRIAL NCT05827068

  4. mRNA-1018 (Pandemic Flu) CLINICAL TRIAL NCT05972174

  5. mRNA-1020 (Flu) CLINICAL TRIAL NCT05333289

  6. mRNA-1030 (Flu) CLINICAL TRIAL NCT05333289

  7. mRNA-1045 (Flu + RSV vaccine) CLINICAL TRIAL NCT05585632

  8. MRNA-1073 (COVID + FLU) CLINICAL TRIAL NCT05375838

  9. mRNA-1083 (Flu + COVID vaccine) CLINICAL TRIAL NCT06694389

  10. mRNA-1189 (EBV vaccine to prevent infectious mononucleosis) CLINICAL TRIAL NCT05164094

  11. mRNA 1195 (EBV vaccine to address EBV sequelae) CLINICAL TRIAL NCT05831111

  12. mRNA-1215 (Nipah vaccine) CLINICAL TRIAL NCT05398796

  13. mRNA-1230 (Flu + COVID + RSV vaccine) CLINICAL TRIAL NCT05585632

  14. mRNA-1273 (COVID-19 vaccine Spikevax®)

  15. mRNA-1273.815 (COVID-19 vaccine adolescents)

(See link for article)

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**Comment**

Similarly to ‘climate change,’ the world is clamoring for more mRNA – mostly due to greed.  There’s a lot of money to be made if you go with the flow, repeat the narrative, and only find what ‘the powers that be’ want you to find.  This has been going on in Lymeland for over 40 years and continues to this day.  It doesn’t matter how many reports of ineffectiveness,  fraud, corruption, danger, and bias come out against ‘climate change,’ or how many reports reveal the dangers of mRNA products. The band plays on….

This should tell you everything you need to know.

For more:

Category:

Activism, Treatment, vaccines

Study: Fatal Malignant Cardiac Tumors Following COVID-19 mRNA Injection

https://www.thefocalpoints.com/p/new-study-fatal-malignant-cardiac

NEW STUDY – Fatal Malignant Cardiac Tumors Following COVID-19 mRNA Injection

Growing body of evidence suggests COVID-19 mRNA injections are likely carcinogenic, contributing to the sharp rise in rapidly progressing, fatal cancers.

Mar 06, 2025

by Nicolas Hulscher, MPH

The study titled, Heart-breaking tumors: a case series of malignant pericardial effusion, was recently published in European Heart Journal – Case Reports:

Background

Malignant pericardial effusions are often linked to metastases from solid tumours, such as those in the lung or breast, or haematological diseases. Primary cardiac tumours are rare, occurring in only 0.02% of cases, with pericardial tumours comprising 6.7%–12.8% of all primary cardiac tumours.

Case summary

In Case 1, a 49-year-old Black African male presented with chest pain and breathlessness after a COVID-19 vaccine. Initially treated for pericarditis, he returned with worsening symptoms. Echocardiography revealed pericardial effusion and cardiac tamponade. Imaging confirmed a right atrial mass diagnosed as malignant biphasic mesothelioma. He died 4 months after diagnosis. In Case 2, a 43-year-old Caucasian male developed breathlessness and fever post-COVID-19 vaccine. Imaging identified a large posterior pericardial mass, later diagnosed as synovial sarcoma. Chemotherapy yielded minor tumour reduction, but he succumbed to his illness, spending his final days in a hospice.

Discussion

Initial clinical signs are critical in determining the origin of pericardial effusion. Malignancy should be suspected in cases with cardiac tamponade, unexplained haemorrhagic pericardial fluid, or recurrent symptoms. Negative cytology warrants further investigation with advanced imaging or biopsy to improve diagnostic sensitivity. Diagnosing rare tumours involves multiple imaging modalities, fluid analysis, biopsies, and an interdisciplinary approach, with pathological analysis being the gold standard. Treatment remains challenging due to the rapid progression of these tumours, with surgery often not feasible. A multi-pronged diagnostic approach is crucial, and clinicians must maintain suspicion for malignancy in persistent pericardial effusion cases, even in the context of other potential confounding factors.

As this study indicates, rapidly progressing fatal cancers shortly following COVID-19 mRNA injection are real, not “disinformation” as the mass media suggests. A growing body of evidence suggests that COVID-19 mRNA injections are likely carcinogenic and have contributed to the alarming rise in cancer rates.  (See link for article)

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For more:

“We must stop messenger RNA [mRNA] at all costs… it’s not only mad, it’s EVIL.” – Dr. Angus Dalgleish, world-renowned ocologist

Category:

Cancer, research, vaccines, Viruses

Metabolic Therapies: Reclaiming Cancer’s Achilles’ Heel Through The Ivermectin, Fenben, and Allulose Revolution

https://www.2ndsmartestguyintheworld.com/p/metabolic-therapies-reclaiming-cancers?

Metabolic Therapies: Reclaiming Cancer’s Achilles’ Heel Through The Ivermectin, Fenbendazole, and Allulose Revolution

WEEKEND FLASH SALE TARGETING CANCER’S METABOLIC CORE STARTS NOW!

2nd Smartest Guy in the World
Mar 07, 2025

The Warburg effect — Otto Warburg’s seminal observation that cancer cells preferentially ferment glucose into lactate even in oxygen-rich conditions — represents a metabolic vulnerability ripe as the perfect therapeutic target for cancer treatment.

Yet, a century after its elucidation, oncology remains tethered to genetic paradigms, sidelining metabolic strategies in favor of cytotoxic and targeted interventions that work at best on about 15% of cancers, representing an abysmal “treatment” model.

Early anecdotal findings of thousands upon thousands of patients show that administering a synergistic combination therapy of repurposed miracle drugs across a large variety of cancers is efficacious in about 80%+ of patients, representing the all-elusive until now ‘holy grail’ cancer cure.

This willful neglect of the cure in plain sight, rooted in Rockefeller Eugenics, allopathic BigPharma, and industrial influences traceable to the early 20th century, has perpetuated a cancer “care” model that prioritizes profit over lives that is designed to relieve patients of the maximum amount of money en route to torturous iatrogenic outcomes, and/or being sent home to die.

Emerging metabolic therapies, including repurposed drugs like Ivermectin (IVM) and Fenbendazole  (FBZ), alongside the rare sugar allulose, challenge this orthodoxy by directly targeting the glycolytic dependency of malignant cells. (Cancer cells are sugar dependent, whereas healthy cells use mostly oxygen to convert to energy stores.)

This highlights the Ivermectin Fenbendazole Allulose revolution sweeping the planet, with recent supply chain strains of IVM and FBZ from India with huge increases in Worldwide demand.

Hundreds of thousands of late stage cancer prognoses are being declared full remission as borders across the world are doing there level best to seize IVM and FBZ on behalf of the corrupt governmental agencies that are bought and paid for by BigPharma and their Deep State partners-in-crime.

We will now explore the mechanisms underlying these agents (Ivermectin, Fenbendazole and Allulose) with Warburg’s insights, and their broader implications for cancer, type 2 diabetes, and obesity—conditions united by metabolic dysregulation.  (See link for article)

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For more:

Category:

Cancer, diet and nutrition, Parasites, Supplements, Treatment

Treating Bartonella: Medical Detective Pts 1-5

https://medicaldetective.substack.com/p/bartonella-the-second-great-imitator

Bartonella: The Second “Great Imitator” Underlying Many Chronic Illnesses – Part 1 of 5

Richard Horowitz
Feb 05, 2025

Bartonella is the third “B” of the triad found in the vast majority of my chronically ill patients who suffer from chronic Lyme disease/PTLDS, along with Borrelia and Babesia.A gram-negative intracellular bacteria, it’s controversial and misunderstood and has been throwing a monkey wrench into my treatments for decades. I barely remember learning about it in medical school, except when they were teaching me about cat scratch fever in children that would cause small, localized rashes (papules) at the site of the scratch with swollen lymph nodes and fevers. It would be treated with a short course of antibiotics like azithromycin. These images show classical cat scratch disease before and after treatment when the lesions are starting to crust up.  (See link for article)

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https://medicaldetective.substack.com/p/bartonella-establishing-the-diagnosis

Bartonella: Establishing the Diagnosis, and the Role of Multiple Bartonella Species and MSIDS Factors in Chronic Illness – Part 2 of 5

Richard Horowitz
Feb 12, 2025

As you learned last week in Bartonella Part 1, this is a very tricky bacteria, with symptoms overlapping many of those associated with chronic Lyme disease and other co-infections. Since there are so many species of Bartonella, the first step is to determine if Bartonella is actually in your body. As a Medical Detective, I know that there are certain clues to follow, but what exactly are they?

Clues to the Existence of Lyme and Bartonella in Chronic Illness

Let’s start at the beginning. You’ve been diagnosed with chronic Lyme disease–you had a prior EM rash and/or filled out the questionnaire and scored above 63, implying a high likelihood of exposure. See the prior Medical Detective Substacks on using this HMQ questionnaire:

https://cangetbetter.com/wp-content/uploads/2021/02/MSIDS-QUESTIONNAIRE-FINALR.pdf

(See link for article)

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https://medicaldetective.substack.com/p/effective-treatments-for-bartonella

Effective Treatments for Bartonella Infections – Part 3 of 5

Richard Horowitz
Feb 19, 2025

Bartonella is an intracellular biofilm/persister bacteria, like Borrelia burgdorferi, the bacterial agent of Lyme disease. For years, many doctors were using single drug therapies for Cat Scratch Disease (CSD), even in the chronic persistent phases of the infection (some may still). This was before we understood the complexity of how this bacteria persists.

Years ago, however, I did recognize that at least 2 intracellular antibiotics were more effective than one for difficult-to-treat intracellular infections. So for many years I treated Bartonella with doxycycline/rifampin or Zithromax/rifampin. Although they helped to knock down symptoms, Bartonella would invariably return after antibiotics were stopped. Persisters persist! (See link for article)

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https://medicaldetective.substack.com/p/treating-bartonella-double-dose-dapsone

Treating Bartonella: Double Dose Dapsone Combination Therapy (DDDCT) – Part 4 of 5

Richard Horowitz
Feb 26, 2025
 
In Bartonella Parts 1, 2, and 3, you learned the basics of Bartonella testing, symptoms, and treatment options, with a detailed discussion of laboratory work needed before starting the protocol, and how/why the medication and support supplements are being used to increase the tolerability and safety of DDDCT and HDDCT. Please review this information with your doctor before proceeding with the antibiotic protocol listed below.  (See link for article)
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https://medicaldetective.substack.com/p/treating-bartonella-2-week-pulses

Treating Bartonella: 2-Week Pulses of Antibiotics for Chronic Bartonellosis – Part 5 of 5

Richard Horowitz
Mar 05, 2025
 
Bravo! You’ve made it to Part 5, the final Medical Detective Substack on diagnosing and treating chronic Bartonella infections. As you read in the previous 4 Substacks, Bartonella is often found in my chronic Lyme patients, at least 80% of the time, right behind active Babesia infections–watch for unexplained fevers, day/night sweats, chills, flushing, “air hunger,” and an unexplained cough if you have ongoing Babesia. (See link for article)
 
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For more:
 

Category:

Bartonella, research, Treatment