Archive for the ‘Activism’ Category

10/4/23 FEMA Emergency Broadcast System Test – Routine or Not?

https://fox59.com/video/fema-fcc-nationwide-alert-test-scheduled-for-oct-4/9045670/  Fox 59 News Story Here  Forbes is already making fun of “conspiracy theories.”

You be the judge.

Keep in mind that many have already stated that EMF, as in 5G, can be used to create almost all the symptoms of COVID or other illnesses.  It can also be targeted to selected individuals and geographical areas. It is also important to note the perfect timing of wide-spread rollout of radiation pumping Smart Meters, with no opt-out option despite many reports of explosions, fires, as well as health problems and people protesting and suing utility companies.

https://justusrhope.substack.com/p/october-4th-fema-test-warning-updated

October 4th FEMA Test Warning

Prepare Without Fear but Don’t Ignore

SEP 30, 2023
The FEMA Test of the Emergency Broadcast System scheduled October 4, 2023 at 2:22 Eastern Time is billed as another routine test. It is likely not.

Why?

For many reasons, contained in my original posts on this subject. The first concerns the dangers of normal 3G and 4G compared to massively increased risks with 5G.

However, the date is rapidly approaching and many if not most remain unaware of the potential dangers. Please carefully listen to Attorney Todd Callender’s [14:05] two interviews where he lays out these issues.

Where is the evidence that we may be dealing with a problem during the October 4 FEMA test?

The short answer contains two points as follows: [I’ve added important points]

#1. Attorney Callender notes this is part of the same MO – Modus Operandi – the Globalists have used these past few years, first with the COVID-19 man-made Bioweapon virus, second with the mRNA ‘vaccine’ which is actually another Bioweapon, and third the Microwave attack on Lahaina Maui. See this link to an article by Sasha Latypova. [Also see this article on the use of 5G, geoengineering, and weather warfare for the globalist agenda as well as possible repurposed drugs useful for Marburg. Please notice the use of antioxidants, NAC and chloroquine.  Remember that the antimalarial hydroxycloroquine is the newer, slightly altered form of chloroquine which has fewer side effects and is considered to be safer.  It was heavily censored/banned but worked for COVID].

They planned Marburg and its subsequent activation with 5G including announcing a Marburg Emergency on December 9, 2020 via a Congressional Act. They added sequences in the designer virus and vax containing Marburg. And they have been steadily building out 5G towers these past few years – with no clear purpose – certainly not for profit or connectivity and not in the Cell Phone Company’s corporate interests. And when 5G was rolled out in China in 2019, we saw reports of numerous sudden deaths among the Chinese. This is massive circumstantial evidence. Not absolute proof, but an  undeniable and robust pattern of circumstantial evidence. It would be foolish to ignore it.

#2. Mainstream Media has not spun this to generate panic. If this were something designed by the Globalists to falsely instill fear – like the COVID-19 Pandemic – it would be part of the narrative. It is not. The media is eerily silent about the details of this test and how it differs from prior ones. This suggests the FEMA test potential danger is being covered up as it is billed as ‘routine’ test and nothing more.

Why is the signal planned to continue for a full two hours? A usual emergency broadcast system test usually lasts less than a minute – for sufficient time to generate a cell phone text. Why two hours? Could it be so Americans are fully exposed to sufficient EMF to accomplish their agenda with regard to the lipid nanoparticles? While citizens go about their daily routine in the middle of the week, during the middle of a workday, all the while unsuspecting and being exposed to two hours of not only 5G, but additional frequencies that target computers, television, and radio. Why are whistleblowers – who have additional knowledge – coming forth and warning?

For both of these reasons, the FEMA test on October 4th is not an innocent and routine measure and likely is something far worse.  (See link for article)

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**Comment**

A FEMA whistleblower came forth and told Callender about the FEMA emergency broadcast test (Oct. 4, 2023 at 2:22 Eastern Time or 1:22 in Wisconsin) which I posted about here:  https://madisonarealymesupportgroup.com/2023/09/25/un-faces-resistance-but-implements-7-year-global-agenda-wef-doubles-down-marburg-via-5g-next/  Scroll down to the article about Attorney Todd Callender which contains an important interview where he discusses how the lipid nanoparticles (filled with all kind of pathogens including 3 different HIV proteins, Ebola, Marburg, staph, e.coli, & are chimeric in nature which means both bacterial and viral) in connection with 5G (18 GHz) will swell causing the pathogens to be released.

This frightening “MUST SEE” 4 minute video also features Callender explaining:

  • after “Operation Warp Speed” excess mortality is up 84%
  • excess diseases are up 1,100%
  • by broadcasting a 18GHz signal for a minute, three times, the Marburg pandemic they’ve already spent the money on will be unleashed
  • the 1P36 gene deletion, also one of the side-effects of the Pfizer shots, will cause those affected to have a disease with “zombie”-like symptoms: violent behavior including abusive-self-injury, hitting or biting people, and extreme, insatiable hunger
  • the CDC published a “Preparedness 101: Zombie Apocalypse” in 2011 supposedly as an example of educational entertainment.  That same year “CONPLAN 8888-11 “Counter-Zombie Dominance” was published.  The Zombie Task Force ended in 2012
  • popular online personality Jason Shurka recently posted a warning that on Oct. 4, 2023 at 2:22 pm Eastern time, FEMA will be using a high frequency signal on the Emergency Broadcasting System (through smart phones, radios, TVs, etc) across the U.S., under the guise of a “test,” to activate graphene oxide and other nanoparticles that have been inserted into billions of humans via the COVID shots.  If the Oct. 4 date does not occur, the backup plan will be to do it on Oct. 11, 2023 at the same time.  He’s states that if this is not stopped, people should shut off their smart phones and all other affected devices at 2 pm Eastern time for two hours to be safe.

All of this begins to make more sense when you consider Dr. McMillan’s recent video on research that has been ignored or ridiculed:  https://madisonarealymesupportgroup.com/2023/10/02/hidden-codes-in-spike-protein-revisiting-snake-venom/  In short, toxin-like peptides found in COVID patients were not produced in human cells but in bacteria.  When they cultured stool from infected patients they found increased levels of RNA in the stool with the bacteria.  When they used specific antibiotics they could reduce or eliminate the bacteria all together.  This strongly suggests the bacteria were making the RNA or pieces of it as well as the unusual toxin-like proteins present in the feces, plasma, and urine.

McMillan states that if all of this was designed to create harm, there is no more effective way than to turn the microbe against the person. 

Let’s all pray this is a big nothingburger, but if it isn’t the author recommends unplugging all computers, TVs, radios and other devices as well as turning 5G cell phones off and placing them in a Faraday cage or a turned-off microwave oven. Use landlines or non-5G flip phones to communicate between 11:00 am and 5:00 pm. If FEMA cancels the October 4th test and reschedules on the backup date of October 11th, all the foregoing still apply.

Hidden Codes in Spike Protein? Revisiting Snake Venom

The following 2021 Italian research is revisited by Dr. McMillan in the video below on how toxin-like peptides were found in samples from COVID patients.  This research which seemed so outlandish at the time causing some to hypothesize that COVID is a type of venom poisoning, has simply been ignored or ridiculed.  Now, after observing patients clinically for two years McMillan postulates, as others have, that this entire mess could have been done on purpose.

Toxin-like peptides found in COVID patients were not produced in human cells but in bacteria.  When they cultured stool from infected patients they found increased levels of RNA in the stool with the bacteria.  When they used specific antibiotics they could reduce or eliminate the bacteria all together.  This strongly suggests the bacteria were making the RNA or pieces of it as well as the unusual toxin-like proteins present in the feces, plasma, and urine.

This website has posted numerous times on how the spike protein itself is toxic and research has now proven that at least half of the “vaccinated” have circulating spike protein systemically within their bodies for at least six months, accumulating in organs and even breast milk  which is causing inflammation in every organ and tissue of the body. Research that has found both spike protein and mRNA persisting in axillary lymph nodes and blood for weeks or even months after vaccination.  Autopsies have also shown mRNA in the hearts of the “vaxxed” in those who died suddenly from cardiac arrests and there is evidence that they are promoting and/or causing turbo cancers.  Also see:  COVID Cancer_CompressPdf

http://

Could There Be Hidden Code in the mRNA Spike Sequence?

Dr. McMillan

Sept. 25, 2023

Dr. McMillan aptly points out that in order to treat someone who has taken a poison, you need to know what that specific poison is. He also states that if this was designed to create harm, there is no more effective way than to turn the microbe against the person.  These codes need to be understood – urgently, and every stone needs to be turned over as an ongoing sickness could be unleashed on entire populations and understanding these codes is required in order to mitigate the damage.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772524/

Version 2.  2021; 10: 550.
Published online 2021 Oct 14. doi: 10.12688/f1000research.54306.2
PMCID: PMC8772524
PMID: 35106136

Toxin-like peptides in plasma, urine and faecal samples from COVID-19 patients

Carlo Brogna, Conceptualization, Formal Analysis, Funding Acquisition, Investigation, Methodology, Project Administration, Resources, Supervision, Writing – Original Draft Preparation, Writing – Review & Editing,#1 Simone Cristoni, Conceptualization, Data Curation, Formal Analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing,#a,2 Mauro Petrillo, Conceptualization, Data Curation, Formal Analysis, Investigation, Methodology, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing,#b,3 Maddalena Querci, Conceptualization, Funding Acquisition, Methodology, Project Administration, Resources, Supervision, Validation, Writing – Original Draft Preparation, Writing – Review & Editing,3 Ornella Piazza, Conceptualization, Methodology, Supervision, Writing – Original Draft Preparation, Writing – Review & Editing,4 and Guy Van den Eede, Conceptualization, Funding Acquisition, Project Administration, Resources, Supervision, Validation, Writing – Original Draft Preparation, Writing – Review & Editing5

Abstract

Background: SARS-CoV-2 that causes COVID-19 disease and led to the pandemic currently affecting the world has been broadly investigated. Different studies have been performed to understand the infection mechanism, and the involved human genes, transcripts and proteins. In parallel, numerous clinical extra-pulmonary manifestations co-occurring with COVID-19 disease have been reported and evidence of their severity and persistence is increasing. Whether these manifestations are linked to other disorders co-occurring with SARS-CoV-2 infection, is under discussion. In this work, we report the identification of toxin-like peptides in COVID-19 patients by application of the Liquid Chromatography Surface-Activated Chemical Ionization – Cloud Ion Mobility Mass Spectrometry.

Methods: Plasma, urine and faecal samples from COVID-19 patients and control individuals were analysed to study peptidomic toxins’ profiles. Protein precipitation preparation procedure was used for plasma, to remove high molecular weight proteins and efficiently solubilize the peptide fraction; in the case of faeces and urine, direct peptide solubilization was employed.

Results: Toxin-like peptides, almost identical to toxic components of venoms from animals, like conotoxins, phospholipases, phosphodiesterases, zinc metal proteinases, and bradykinins, were identified in samples from COVID-19 patients, but not in control samples. 

Conclusions: The presence of toxin-like peptides could potentially be connected to SARS-CoV-2 infection. Their presence suggests a possible association between COVID-19 disease and the release in the body of (oligo-) peptides almost identical to toxic components of venoms from animals. Their involvement in a large set of heterogeneous extra-pulmonary COVID-19 clinical manifestations, like neurological ones, cannot be excluded. Although the presence of each individual symptom is not selective of the disease, their combination might be related to COVID-19 by the coexistence of the panel of the here detected toxin-like peptides. The presence of these peptides opens new scenarios on the aetiology of the COVID-19 clinical symptoms observed up to now, including neurological manifestations.

Lyme Disease Patients Detail Treatment-Denial Conspiracy at Fifth Circuit

https://www.courthousenews.com/lyme-disease-patients-detail-treatment-denial-conspiracy-at-fifth-circuit/

Lyme disease patients detail treatment-denial conspiracy at Fifth Circuit

Lyme disease sufferers say they had trouble finding doctors willing to treat them due to a scheme to deny care by insurers and infectious disease experts.

Article Excerpts:

(CN) — A group of Lyme disease patients asked the Fifth Circuit on Thursday to revive their lawsuit against a medical society they claim issued bogus guidelines that insurers used to deny them coverage, forcing some to pay hundreds of thousands of dollars for their care.

Lisa Torrey and 27 others sued the Infectious Diseases Society of America, or IDSA, seven health insurance companies and several medical doctors in 2017 in Texarkana, Texas, federal court.

Bringing RICO Act and antitrust claims, the plaintiffs claim several major health insurers decided treating Lyme disease was too expensive, so they paid IDSA-affiliated doctors to establish arbitrary guidelines, first published in 2000, that said the illness could be treated with 28 days of antibiotics.

After reaching confidential settlements with the insurers, the plaintiffs filed a second amended complaint in January 2021, adding fraudulent and negligent misrepresentation claims against the IDSA and its panelists who wrote the guidelines. (See link for article)

__________________

SUMMARY:

  • A U.S. District Judge sided with the IDSA and dismissed the case
  • Although appealed, the IDSA convinced the appellate court to dismiss it as premature since the settlement hadn’t been finalized
  • The plaintiffs filed another appeal and a 3-judge panel of the 5th circuit heard arguments recently
  • The judge is leaning toward dismissing the lawsuit as it is about a scientific issue that needs a forum for debate
  • The challengers’ lawyer made the argument that more than 12 states have passed legislation to protect physicians’ ability to prescribe long-term treatment proving that in reality doctors are bound by IDSA “guidelines,” as well as the fact insurance companies hide behind these “guidelines” which have become mandates allowing them to deny payment for treatment

UN Faces Resistance But Implements 7-Year Global Agenda, WEF Doubles Down, & Marburg Via 5G Next

**UPDATE**

Before 2030, there was Agenda 21.  Please watch the following 12 minute video for historical background on the UN Agenda and the fact it started in 1992 and has been steadily worked on since. We were warned way back then by those paying attention. 

http://

Wilderness Areas Connected By Corridors Protected by Buffer Zones But No Humans Allowed

The United Nation’s documents are very clear.  For any community that opposed their diabolical ecosystem management concept, all 20 federal agencies descended upon the community and began inspections and writing tickets. According to U.S. State Department documents as well as UNESCO documents, the ‘man in the biosphere’ program is the first step in implementing the convention on biological diversity, and there are 47 of these ‘man in the biosphere’ programs around this nation that occupy about 51 million acres of U.S. soil.  

Once again, similarly to the WHO ‘Pandemic Treaty,’ this plan is a global monopoly with the taxpayer completely in the dark but footing the bill.
The document, ‘The Future We Want’, recognizes that there will be significant impacts on all societies; that they have economic, cultural and social drivers; and that they are likely to be accentuated in the coming decades. The global community is advancing towards the and implementation of a comprehensive set of related Sustainable Development Goals (SDGs) and targets to simultaneously address human needs and environmental change. These explicitly take into account other global imperatives, such as the targets set under the United Nations Framework Convention on Climate Change (UNFCCC) and its protocols, and the Convention on Biological Diversity’s (CBD) Strategic Plan for Biodiversity 2011-2020, including the Aichi Biodiversity Targets.  Source
This is why ‘climate change’ must be pushed at all costs, even if it’s wrong.  There’s a long on-going agenda and in order to achieve an end-goal, the climate must be seen as an ’emergency.’

https://themostimportantnews.com/archives/while-barely-anyone-was-watching-leaders-at-the-un-made-a-7-year-agreement-to-implement-a-single-global-agenda

While Barely Anyone Was Watching, Leaders At The UN Made A 7 Year Agreement To Implement A Single Global Agenda

Article Excerpts:
On Monday and Tuesday, officials from all over the world gathered in New York City to commit their nations to fully implement the 2030 Agenda and the Sustainable Development Goals over the next 7 years.  If you are not familiar with the 17 Sustainable Development Goals, you can find them right here.  They are essentially a blueprint for how the globalists want the world to be run.  Just about every area of human activity is covered by the 17 Sustainable Development Goals, and it would take extreme measures over the next 7 years in order to achieve all of them by the deadline.

The “Political Declaration” is 10 pages long, and you can read it for yourself right here.

The globalists are absolutely determined to meet their climate goals, and all the rest of us will suffer as a result.

On the tenth page of the document that the global leaders at the UN just adopted,  “the Summit of the Future in 2024” is referenced…

We look forward to the Summit of the Future in 2024 as an important opportunity to, inter alia, accelerate the implementation of the 2030 Agenda and its SDGs.

This exceedingly important meeting will be held just two months before the next presidential election in the United States.

At that gathering, UN member states are scheduled to adopt something called “a Pact for the Future”.

You can read about “the Summit of the Future” and the “Pact for the Future” on the official UN website right here.  (See link for article)

__________________

**Comment**

Our current administration is fully behind all of this.

In short, the Pact will give the UN overarching power when a “global shock” occurs. A UN policy paper explained that for a future pandemic, a “major event in outer space” or even “unforeseen risks” would all qualify.

Go here for graphic and article about what is behind Agenda 2030 & a one world government.

https://shabnampalesamohamed.substack.com/p/united-nations-faces-power-grab-resistance

United Nations faces power grab resistance from countries refusing to be bulldozed

International law professor Francis Boyle said “This is very dangerous. We cannot underestimate its significance. It’s like a stick of dynamite ready to be exploded.”

SEP 23, 2023
Article Excerpts:

“Regardless, acting as the UN’s general assembly, its 78th president Dennis Francis tried to irregularly and unlawfully approve a ‘historic’ but currently non-binding political declaration on pandemics and other areas related to health, free speech and national sovereignty”. International renowned law professor Francis Boyle said “This is very dangerous. We cannot underestimate its significance. It’s like a stick of dynamite ready to be exploded.”

By Shabnam Palesa Mohamed

The United Nations is facing one of the worst scandals in its controversial history, caused by its brazen tendency to defy democratic principles and disrespect national sovereignty. This time, given significant socio-political developments, the world is paying attention.

During the latter part of this September, the UN held its SDG Summit and its 78th General Assembly. At the top of its agenda for the 19th and 20th, was, inter alia, the adoption of a high level political declaration on pandemic prevention, preparedness, and response.

What was the response from the United Nations and World Health Organization?

• Blatantly ignoring the official letter to the UN, the WHO Director-General Adhenom Tedros Ghebreyesus incorrectly said “As you know, this morning, the 193 Member States of the United Nations approved the political declaration on pandemic prevention, preparedness and response. The declaration is a strong signal from countries that they are committed to learning the lessons of the COVID-19 pandemic, and to strengthening the world’s defenses against pandemics.”

• He continued with almost delusional dishonesty “In the declaration approved today, Member States have demonstrated that even at this time of division and polarization, it’s still possible for countries to come together to agree on a shared response to shared threats. It is that same spirit of collaboration that we urge countries to demonstrate as they continue their negotiations on the Pandemic Accord and the amendments to the International Health Regulations.”

Francis Boyle, J.D., Ph.D., a bioweapons expert and professor of international law at the University of Illinois, who drafted the Biological Weapons Anti-Terrorism Act of 1989, stated:

“The danger here is that this is a Statement by Heads of State and Heads of Government, either one of whom can bind their states under international law and all of whom together could arguably create customary international law. That is what the Drafters of this Statement intended. This is very dangerous. We cannot underestimate its significance. It’s like a stick of dynamite ready to be exploded. This is all part of the Globalists Strategy to create a Worldwide Totalitarian Medical and Scientific Police State under the guise of the WHO. Thanks. Then if the 11 vote this way against it, then that will prevent this Declaration being adopted by Consensus and thus arguably becoming part of customary international law, which is what those behind the Declaration intend.”

Call to Action:

1. Raise your voice against the UN – WHO power grab. CHD Africa will deliver names and countries (only) to UN and WHO leaders (1 minute)
2. Share this article with your family, community, organisations, and media on all sides of the fence (as often as you can)
3. Share this article with your country’s political and diplomatic representatives (with urgency and please follow up)
4. Sign up to CHD Africa’s newsletter for news, analysis, updates and calls to action (immediately for full access)
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(See link for article)

____________________

https://thepeoplesvoice.tv/wef-calls-for-free-speech-concentration-camps-to-jail-first-amendment-terrorists/  Video Here

WEF Calls For Free Speech Concentration Camps To Jail ‘First Amendment Terrorists’

Article Excerpts:
The world has reached a critical juncture according to Klaus Schwab who has ordered world governments to begin jailing and re-educating anybody who opposes the globalist agenda.

According to Schwab, human history is now officially over and anybody who disagrees with the globalist agenda must be canceled, de-platformed, arrested and imprisoned as an example to the rest of society.

It is no surprise that New York is the first US state to forge ahead with the instructions.

As Rochester First reported this week, oral arguments were held in an appeal case over quarantine regulations by the NY Department of Health over a regulation that would allow the Commissioner of Health to issue isolation or quarantine orders to control the spread of a communicable disease. (See link for article and video)

__________________

https://rumble.com/v3hpvti-todd-callender-govt-will-trigger-deadly-marburg-pandemic-with-5g-covid-was  Video Here (Approx. 57 Min)

Attorney Todd Callender: Gov’t Will Trigger Deadly MARBURG Pandemic With 5G…

Covid Was a Trial Run

Despite only 10 Marburg deaths in 40 years our government has a Marburg Pandemic Declaration, Dec. 2020 Fed Register (PDF) by Congress:
https://www.govinfo.gov/content/pkg/FR-2020-12-09/pdf/2020-26972.pdf

This was done because because it has an effect upon the applicable law.  There are stand-by laws which are in place after a pandemic declaration is given.  These declarations suspend our Constitutional and human rights, including informed consent.

When Biden declared a national emergency in March, 2020 – our Constitutional rights were suspended.  It also solidified all power to the Executive Branch, which is essentially martial law.  When he declared a public health emergency, our human rights were suspended, which is why they legally are getting away with experimenting upon humans with the COVID shots.

Callender is the first attorney to sue the DOD, HHS, and FDA due to “vaccine” mandates and has acquired 400,000 military plaintiffs, thousands of which have provided whistleblower evidence.

Starting at 11:00, Callender discusses how the lipid nanoparticles (filled with all kind of pathogens including 3 different HIV proteins, Ebola, Marburg, staph, e.coli, & are chimeric in nature which means both bacterial and viral) in connection with 5G (18 GHz) will swell causing the pathogens to be released.

This frightening 4 minute video also features Callender explaining numerous important points:

  • after “Operation Warp Speed” excess mortality is up 84%
  • excess diseases are up 1,100%
  • by broadcasting a 18GHz signal for a minute, three times, the Marburg pandemic they’ve already spent the money on will be unleashed
  • the 1P36 gene deletion, also one of the side-effects of the Pfizer shots, will cause those affected to have a disease with “zombie”-like symptoms: violent behavior including abusive-self-injury, hitting or biting people, and extreme, insatiable hunger
  • the CDC published a “Preparedness 101: Zombie Apocalypse” in 2011 supposedly as an example of educational entertainment.  That same year “CONPLAN 8888-11 “Counter-Zombie Dominance” was published.  The Zombie Task Force ended in 2012
  • popular online personality Jason Shurka recently posted a warning that on Oct. 4, 2023 at 2:22 pm Eastern time, FEMA will be using a high frequency signal on the Emergency Broadcasting System (through smart phones, radios, TVs, etc) across the U.S., under the guise of a “test,” to activate graphene oxide and other nanoparticles that have been inserted into billions of humans via the COVID shots.  If the Oct. 4 date does not occur, the backup plan will be to do it on Oct. 11, 2023 at the same time.  He’s states that if this is not stopped, people should shut off their smart phones and all other affected devices at 2 pm Eastern time for two hours to be safe.

Show Links:
The Role of Law Enforcement in Public Health Emergencies (PDF)
https://www.ojp.gov/pdffiles1/bja/214333.pdf

Lyme Pain

https://danielcameronmd.com/lyme-pain/

LYME PAIN

Lyme pain

Welcome to another selection from my book “An Expert’s Guide on Navigating Lyme disease.” The books highlights the findings of my first 600 Lyme disease Science blogs.  In this episode, I will discuss Lyme pain.

Reported pain associated with Lyme disease includes headaches, eye pain, neck pain, chest pain, abdominal pain, bladder pain, joint pain, and neuropathy. More recently, central sensitization syndrome (CSS) has been described. Pain medication may not be as effective as when used for other illnesses. Thankfully, pain often improves upon successfully treating Lyme disease.

CENTRAL SENSITIZATION SYNDROME AND LYME DISEASE.

Chronic pain, debilitating fatigue, and heightened sensory disturbances are common in Lyme disease patients. In the article “Post-Treatment Lyme Syndrome and Central Sensitization,” it is suggested that in some cases, such symptoms may be due to central sensitization syndrome (CSS) (Batheja et al., 2013). Central sensitization syndrome (CSS) involves changes in the central nervous system, particularly the brain and spinal cord. This syndrome “is thought to involve hyperactivation of central neurons, leading to various synaptic and neurotransmitter/ neuromodulator changes” (Batheja et al., 2013).

“Notably, in relation to Lyme disease, infections, in general, are known to activate central sensitization in some patients, possibly through the release of inflammatory cytokines,” Batheja points out. Read more.

LYME PRESENTING AS ABDOMINAL PAIN IN A BOY.

At age 8, a boy was hospitalized for severe abdominal pain and underwent extensive testing, but the results were negative. His abdominal pain remitted over the next two months (Savasta et al., 2020).

One year later, the boy was admitted with learning difficulties including attention deficit, difficulty speaking, irritability, and difficulty walking due to an ataxic gait.

He was diagnosed with abdominal neuroradiculopathy. Additional laboratory and radiological findings confirmed the diagnosis of late Lyme disease.

He was treated with six weeks of oral and IV antibiotics. Three months after treatment, the boy’s gait and scholastic performance had improved and entirely resolved after one year. Read more.

A WOMAN WITH A HISTORY OF LYME WITH PAIN REFRACTORY TO TREATMENT.

Lyme disease patients often suffer from ongoing illness following treatment. A study found that 31% of patients remained in significant pain for months after a three-week course of doxycycline to treat an erythema migrans rash (Bechtold et al., 2017).

Researchers describe a 31-year-old woman with Post-Treatment Lyme disease Syndrome (PTLDS) “whose pain was refractory to treatment options such as radiofrequency ablation, vitamin infusion therapy, opioid analgesics, and other pharmacotherapies.” Her pain began gradually, three years prior and a short time after being diagnosed and treated for Lyme disease. “The patient complained of diffuse body pain (6–7/10), fatigue, headache, and brain fog (7–8/10)” (Hanna et al. 2017).

The patient was prescribed off-label Ketamine for pain, reducing her pain by 71%. Read more.

BREAST CANCER PATIENT DEVELOPS LYME DISEASE.

A 61-year-old woman was diagnosed with stage II breast cancer with lymph node metastasis. She underwent a lumpectomy, followed by chemotherapy, radiation, and anti-estrogen treatment, letrozole.

One year later, the woman complained of radicular leg and back pain followed by a foot drop on one foot and right-sided facial palsy in two weeks. Moreover, she was in severe pain despite narcotics.

A spinal tap was performed due to unexplained neurologic findings. Lyme disease tests by blood and spinal fluid were positive.

She was diagnosed with Lyme disease and treated with intravenous ceftriaxone for 14 days. As a result, she became pain-free despite her history of severe pain despite narcotics. Read more.

LYME PRESENTING WITH SEVERE NEUROPATHIC PAIN.

A 36-year-old man suffered from a chronic pain syndrome associated with Post-Treatment Lyme Disease Syndrome (PTLDS) (Karri and Bruel, 2020). The doctors did not offer antibiotic treatment.

The patient described severe neuropathic pain in both feet and categorized the pain at a level 10 out of 10 despite treatment with methadone 5 mg every 4 hours as needed. The doctors assumed that the tick-borne infection had resolved, and elected not to treat it with antibiotics.

Instead, they treated the patient’s symptoms. The pain remained severe despite trials of gabapentin, duloxetine, bupropion, and narcotics. Two surgical procedures were performed, which improved the patient’s pain.

Author’s note: I might have retreated with an antibiotic. Read more.

LYME DISEASE CASE WITH SEVERE PAIN FOR 9 YEARS.

In an article published in Saudi Journal of Anaesthesia, doctors describe the case of a 23-year-old woman who suffered from severe chronic pain for 9 years due to post-treatment Lyme disease syndrome (PTLDS). Her pain intensified and became more difficult to manage after she underwent dental extractions and required hospitalization.

Out of 19 symptoms associated with Post-Treatment Lyme Disease Syndrome (PTLDS), 9 were especially significant and included fatigue, joint pain,  focusing/concentration, muscle pain, memory, finding words, sleep, neck pain, and irritability. The remaining symptoms were paresthesias (tingling sensations), low back pain, headache, photophobia, dizziness, visual clarity, chills, coordination, sweats, fasciculations (muscle twitches), breathing difficulties, urination changes, and nausea (Rebman et al., 2017).

Two participants met the criteria for postural orthostatic tachycardia syndrome (POTS). Results from the physical exam and laboratory testing of our sample of patients with PTLDS did not show a pattern of significant objective abnormalities.” However, “the most notable exception was the higher rate of diminished vibratory sensation on physical exam among participants with PTLDS. Read more.

LYME DISEASE PAIN AFTER DENTAL SURGERY.

Despite an uneventful extraction of four molars, a woman complained of severe widespread pain. Her pain medication list was extensive. The woman’s oral pain was minor, while her main issue was overall body pain (Lim and Kinjo Lim 2018).

Although the physicians used a multimodal pain regimen during surgery, they could not prevent her Lyme disease symptoms from recurring after surgery. Finally, the patient’s pain became so severe that she was transferred to the Intensive Care Unit (ICU). “A multimodal pain regimen was used for two days that include ketamine infusion, acetaminophen, ketorolac, oxycodone, and hydromorphone” (Lim and Kinjo Lim 2018).

Author’s note: It would be reasonable to revisit the woman’s PTLDS clinical history to determine whether she was adequately treated for her infection. Read more.

COMPLEX REGIONAL PAIN SYNDROME (CPRS) FROM LYME.

A review from Raigmore Hospital in the UK discussed autonomic dysfunction due to infectious diseases. “Complex regional pain syndromes [CRPS] and reflex sympathetic dystrophy (RSD) with regional sympathetic hyperactivity have also been reported in some patients with Lyme disease” (Artal 2017). CRPS is characterized by considerable pain (allodynia, hyperalgesia), edema, trophic changes of the skin and muscles, and sudomotor disorders.

Artal discussed a case first described by Sibanc et al. (2002). A 46-year-old man reported increasing pain and swelling in his left foot. The pain eventually caused his leg to become dysfunctional. “Even the slightest contact with the skin of the affected area caused the patient unbearable pain” (Sibanc and Lesnicar, 2002). The man improved after four weeks of intravenous ceftriaxone. Read more.

FATIGUE AND COGNITION FROM CENTRAL SENSITIZATION SYNDROME?

Fatigue and cognitive impairments are prominent features of central sensitization syndrome. Patients with Post-treatment Lyme disease Syndrome or chronic Lyme disease often have persistent insomnia and fatigue. While fatigue can have a central or peripheral origin, “central fatigue often has the significant correlate of cognitive impairment” (Batheja et al., 2013).

Studies of patients with Post-treatment Lyme disease Syndrome “have shown that problems with memory, working memory, processing speed, and verbal fluency are common” (Batheja et al., 2013).

Central sensitization syndrome has been described in several illnesses characterized by fatigue with similar presentations to Lyme disease, including fibromyalgia and chronic fatigue syndrome (Batheja et al., 2013). Read more.

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