Tonight: “Lyme Brain & Fibro Fog” With Dr. Rawls
|
|
|
|
https://tickbootcamp.com/episode-300-ahead-of-the-curve-an-interview-with-dr-alan-mcdonal Interview Here (Approx. 2 hours 13 min)
Dr. Alan MacDonald is an Ivy League educated Medical Doctor who worked as a hospital pathologist in the eastern Long Island, New York area at the outset of the modern Lyme disease pandemic. He and his pioneering work were first featured on episode 171 of the Tick Boot Camp Podcast.
In this comprehensive interview, Dr. MacDonald discusses his groundbreaking and yet to be published research findings on topics such as the Lyme disease connection to suicide, brain cancer, Leukemia, dementia, Alzheimer’s disease, and Parkinson’s disease, in addition to how acute Lyme disease disrupts liver function and why and how Lyme disease testing is flawed.
PS you can also view an exclusive Tick Boot Camp presentation created by Dr. MacDonald with photos of Lyme under a microscope and descriptions highlighting the various topics discussed in this interview
Check out his GoFundMe page to help him continue his groundbreaking work.
McDonald has truly done ground-breaking work but has been vilified by many of his own colleagues who seemingly can’t think outside the box or accept new information. Go here to watch other videos where he shows parasitosis (Neural Larval Migrans) within MS patients as he discovered nematode worms, eggs and both larval forms and mating adult pairs present in the brain and spinal fluid of MS patients. These videos are circa 2016 and are revolutionary yet are quietly collecting dust and simply ignored in mainstream research.
At 5 min and 51 sec into the 2016 London lecture, you will see the discovery of worms in the brain and spinal fluid of EVERY MS patient tested. He also explains the difficulty in finding these worms as they move from one area to another.
CLICK HERE to view the research poster of Dr. MacDonald’s discovery of filarial (small roundworms) in the central nervous system of MS patients at their time of death.
CLICK HERE to view the research poster of Dr. MacDonald’s discovery of tapeworm larva and developing juvenile tapeworms in the central nervous system of MS patients at their time of death.
What this means regarding treatment, is that if you are one of those patients with these worms, you need to disable/kill the worms to get to the borrelia/MSIDS inside them. Anthelminitics such as ivermectin and Albenza are used to kill worms as well as natural medicines; however, this must be done under the supervision of a doctor as the inflammation and herxheimer reactions can be very great.
For more:
https://childrenshealthdefense.org/defender/depression-chemical-imbalance-theory-big-pharma-profits/
After reviewing decades of research, a group of University College London scientists concluded there’s no evidence changes in serotonin levels cause depression. But the chemical imbalance theory — which overnight gave drugmakers a highly profitable income stream, doctors a ready-made, patient-pleasing tool, the media, reliable new advertisers and Wall Street, hot new stocks — remains popular.
By Martha Rosenberg
“Lexapro appears to relieve the symptoms of depression and anxiety by increasing serotonin,” says an ad on the Bonkers Institute, a website that archives drug ads and also satirizes pharma claims and shaky science.
“Zoloft works to correct a chemical imbalance in the brain which may be related to symptoms of depression,” another ad says.
“Paxil CR blocks serotonin from being reabsorbed back into the sending nerve cell. This process increases the availability of serotonin to the receiving nerve cell and may help message [depression] transmission return to normal,” a third ad says.
As many Epoch Times readers may have heard, the serotonin “chemical imbalance” theory of depression was recently put to rest by a group of University College London scientists in the journal Molecular Psychiatry.
________________
SUMMARY:
Important quote:
As Mark Horowitz, co-author of the Molecular Psychiatry article, put it, “One interesting aspect in the studies we examined was how strong an effect adverse life events played in depression, suggesting low mood is a response to people’s lives and cannot be boiled down to a simple chemical equation.”
If depression comes from stress, trauma, grief, loneliness and social conditions such as poverty, as Horowitz suggests, it wouldn’t be amenable to medication treatment.
Regarding depression, and mental health in general, I found that my low mood paralleled with how I felt physically. In other words, the worse I felt physically, the worse I felt mentally. Getting to the root of the problem (infections) with appropriate, effective antimicrobial treatment is key and the best and first place to start; however, as always – we are all so very different.
Some patients will really have to deal with past trauma like my husband. The more trauma that happened to you before you became infected, the more this will rear its ugly head. Nobody really talks about this, but it is yet another crucial issue as we must deal with the body, mind, and spirit. Since Lyme/MSIDS infects the brain, it does a number on your emotions as well as your hormones, neurotransmitters, etc. – all of which can extrapolates out to having to deal with things you thought you had forgotten or dealt with long ago. Nope. It all comes back to haunt you in the wee hours of the night when you have unrelenting insomnia. Developing tools/skills to deal with this will be another challenge in this pot-holed riddled journey. I’m no expert in this but for us we talked and prayed a lot – often between the hours of 3-5 a.m. Here’s a few resources, particularly on fear as this is a common emotion of Lyme/MSIDS patients as they struggle with feeling no longer in control of their body and mind:
Inflammation appears to be a huge disease driver and lowering inflammation will help every other issue. There are many things you can experiment with at home and as always – bounce things off of your doctor to make sure what you add doesn’t have negative interactions with what you are already taking. Lyme literate doctors are versed in all of this as it’s a common problem for those struggling with infections.
My only advice is only try ONE thing at a time so you can track progress and know if it’s helping or not. No sense in paying for things that don’t work. If it doesn’t help – drop it and move on to experiment #2, 3, 4 and so on until you find something that helps. IF something helps BUT you can still improve, then it’s time to begin layering in other things ONE AT A TIME, making sure to keep track of responses. This has been how we have gotten to the other side of health. Effective, antimicrobial treatment for Lyme/MSIDS was the BIG important necessary step, but then we have had to add in many supplements/treatments to lessen and eliminate symptoms that remained.
Notice how the patient in the article had a mold problem. In my experience, patients who have tick-borne illness and mold are some of the sickest people I know. The mold MUST be dealt with or the patient will not improve. The same could be said about having MCAS, the inability to detox, and so many other issues.
https://www.lymedisease.org/neuropsych-symptoms-lyme-tbds/

Lyme disease and co-infections can bring on a variety of neuropsychiatric symptoms, such as pain, seizures, and cognitive impairment. Yet, patients often find that their doctors don’t understand the connection.
In a recent study, Sarah Maxwell, PhD, and co-authors compared official public health information, case reports, medical literature, and the self-reported symptoms of patients with Lyme and other tick-borne diseases. In the following article, she explains what the researchers found.
By Sarah Maxwell, PhD
Currently, the Centers for Disease Control and Prevention (CDC) does not recognize most neuropsychiatric symptoms of Lyme and other tick-borne diseases. This leaves medical providers with scant information regarding the full extent of possible symptom presentation, to the detriment of patients.
Patients would be better served by improved public health recognition and communication regarding the full spectrum of possible tick-borne disease related symptoms, some of which can be quite frightening, such as hallucinations.
In our recent lead article in Healthcare, we found that neuropsychiatric symptoms are prevalent in the medical literature and among patients’ self-reports, but are not recognized by public health officials, specifically the CDC’s: Tickborne Diseases of the United States: A Reference Manual for Health Care Providers.
In the article, we note that, “The complexity of diagnosis originates from patients presenting with non-specific and multisystem symptoms, with potential misattribution of symptoms by practitioners, regarding psychiatric and associated neurological problems.”
Our mixed-methods approach included a systematic review of the literature on psychiatric and neurological symptoms of tick-borne diseases. We then compared the medical literature to the CDC’s publication: Tickborne Diseases of the United States: A Reference Manual for Health Care Providers.
We found that out of all the neuropsychiatric symptoms reported in the medical literature for common tick-borne diseases, only a few were fully recognized by public health officials.
The table below summarizes the symptoms presented in our study. Column one lists symptoms. Column two lists the tick-borne diseases associated with those symptoms in the medical literature. The third column lists the tick-borne diseases that are associated with the symptom, if any, as recognized by the CDC. The final column shows symptoms that are reported in the literature but not recognized by the CDC.
For example, in the medical literature, the symptom, “difficulty with, or slurred speech (dysarthria),” is associated with five tick-borne diseases: Lyme disease, anaplasmosis, ehrlichiosis, Powassan virus disease (PVD), and Rocky Mountain Spotted Fever (RMSF).
However, the CDC does not recognize dysarthria as a symptom of any tick-borne disease, as noted in the fourth column.
Panic attacks and hallucinations are additional examples reported among Lyme disease patients, but also not recognized in public health guidance to physicians.
Table 1. Symptom comparison from medical literature and the public health reference manual for common tick-borne diseases.
(RMSF—Rocky Mountain spotted fever; BMD—Borrelia miyamotoi diseases; PVD—Powassan virus disease; TBRF—Tick-borne relapsing fever.)
| Symptom | Reported in Scientific and Medical Literature | Reported by the CDC | Reported in the Scientific Literature, but Not Recognized by the CDC |
| Headache | Lyme disease, BMD, babesiosis, ehrlichiosis, tularemia, anaplasmosis, RMSF, and PVD | Lyme disease, ehrlichiosis, babesiosis, anaplasmosis, RMSF BMD, PVD, and tularemia | None, headache is the most common presenting neurological symptom among all TBDs |
| Confusion/Altered Mental Status | Lyme disease, babesiosis, ehrlichiosis, anaplasmosis, and PVD | Confusion: BMD
Altered mental status: ehrlichiosis, babesiosis, RMSF, and PVD |
Lyme disease,
anaplasmosis |
| Pain | Lyme disease, babesiosis, ehrlichiosis, anaplasmosis, tularemia, RMSF, and PVD | Lyme disease, babesiosis, ehrlichiosis, anaplasmosis, tularemia, RMSF, and PVD | PVD |
| Seizures | Lyme disease, RMSF | PVD | Lyme disease, RMSF |
| Vertigo/Dizziness | Lyme disease, RMSF | None | Lyme disease, RMSF |
| Tingling/Numbness | Lyme disease | None | Lyme disease |
| Cognitive Function (concentration, memory difficulty, and word recall) | Lyme disease | None | Lyme disease |
| Paralysis: difficulty swallowing (dysphagia) or Bell’s palsy | Bell’s palsy: ehrlichiosis
dysphagia: Lyme disease |
Bell’s palsy: Lyme disease, ehrlichiosis, babesiosis
dysphagia: none |
Dysphagia: Lyme disease |
| Difficulty with, or slurred speech (Dysarthria) | Lyme disease, anaplasmosis, ehrlichiosis, PVD, and RMSF | None | Lyme disease, anaplasmosis, ehrlichiosis, PVD, RMSF |
| Low Blood Pressure (hypotension) | babesiosis, ehrlichiosis, and anaplasmosis (also present in TBRF) | babesiosis | ehrlichiosis, anaplasmosis, and TBRF |
| Fainting (syncope) | Lyme disease, babesiosis | None | Lyme disease, babesiosis |
| Depression | Lyme disease, babesiosis | babesiosis, but uncommon | Lyme disease |
| Anxiety | Lyme disease (also present in TBRF) | None | Lyme disease |
| Fatigue and malaise | Lyme disease, ehrlichiosis, anaplasmosis, and babesiosis | Lyme disease, ehrlichiosis, anaplasmosis, babesiosis, and tularemia (and other TBDs) | None, fatigue and malaise are commonly agreed upon as classic symptoms of TBDs |
| Mania, panic attacks, delusions, or hallucinations | Lyme disease | None | Lyme disease |
We also compared patient self-reported neuropsychiatric symptoms to those recognized by the CDC and the medical literature.
We discovered that patient self-reported symptoms aligned well with the medical case reports, but generally were not recognized by the CDC.
Through an online survey using a convenience sample of patients with self-reported tick bites and concomitant Lyme and other tick-borne diseases, we evaluated patient reports of neuropsychiatric symptoms.
Anxiety, depression, panic attacks, hallucinations, delusions, and pain—ranging from headaches to neck stiffness and arthritis—were common among patients who report a tick-borne disease diagnosis.
Overall, pain and psychiatric symptoms were dominant presentations among survey respondents across all TBD diagnoses, with the majority reporting anxiety, depression, and panic attacks.
Additional reported symptoms also included those not acknowledged by public health officials, including delusions, hallucinations, and Obsessive Compulsive Disorder (OCD).
In contrast, Bell’s palsy, often noted as a classic sign of Lyme disease by public health officials, was reported less frequently by the respondents than psychiatric presentations.
Public health guidance does not align with the medical literature or with patient self-reported symptoms in our study.
We conclude that, “Given the multitude of non-specific patient symptoms this study indicates the need for a revised approach to tick-borne disease diagnosis. Our findings suggest the need for improved awareness of the wide range of associated symptoms and communication from official public health sources regarding tick-borne diseases.”
Click here to read the full article.
Sarah Maxwell, PhD, is an assistant provost and associate professor at the University of Texas at Dallas. Her research and grants focus on tick-borne disease surveillance and patient experiences with Lyme disease. She also serves on the scientific board of the Texas Lyme Alliance.
Aug 2, 2022 —
Latest email to the Federal Tick-Borne Disease Working Group…
———- Original Message ———-
From: CARL TUTTLE <runagain@comcast.net>
To: “tickbornedisease@hhs.gov” <tickbornedisease@hhs.gov>
Cc: (All members of the TBDWG)
Date: 08/02/2022 9:40 AM
Subject: Borrelia burgdorferi spirochetal brain infection and Lewy Body Dementia
To the Tick-Borne Disease Working Group,
Please see the attached publication from Pathologist Alan MacDonald who has discovered borrelia burgdorferi spirochetal brain infection and Lewy Body Dementia.
Microbial DNA globular liquid crystal like deposits inside Lewy bodies in four Lewy dementia patients
https://www.dropbox.com/s/t38vv4vgx5wow5z/MacDonald%20A%20Lewy%20Body%20Dementia%20%26%20Lyme%20Neuroborreliosis%20Medical%20%26%20Clinical%20Rsearch%20Aug%202022.pdf?dl=0
Alan B MacDonald
Abstract
Four autopsy brains demonstrated concurrent evidence of Diffuse Cortical Lewy Body Dementia and active Lyme neuroborreliosis in adjacent brain sites. Lewy bodies In DCLBD contain microbial DNA. Alpha Synuclein proteins, which intrinsically bind to human nuclear DNA also bind to microbial DNA deposits inside Lewy bodies in the cytoplasmic compartment of diseased neurons. This is the first report of an association between spirochetal brain infection and Lewy Body Dementia.
This is just one additional piece of evidence as identified in my Verbal Public Comment that there has been a 30yr deliberate mishandling/avoidance of Lyme disease while refusing to recognize its severity.
Now would be a good time to review how the deception was pulled off using taxpayer dollars through a grant issued by the CDC; an open checkbook handed to Gary Wormser to produce his junk science focusing on the acute stage of disease with bulls-eye rash and early treatment under Grant# RO1 CK 000152
2019 Communication Sent to the TBDWG:
———- Original Message ———-
From: CARL TUTTLE <runagain@comcast.net>
To: gwormser@nymc.edu, tickbornedisease@hhs.gov, brett.giroir@hhs.gov
Cc: mark.dayton@state.mn.us, daniel.tillson@mail.house.gov, kvf1@comcast.net, olx1@cdc.gov, iturko@umd.edu, allen.l.richards.civ@mail.mil, scott.cooper@cms.hhs.gov, ddutko@hanszenlaporte.com, kalachakra108@aol.com, chris.smith@mail.house.gov, adam.durand@mail.house.gov, Anthony.Fauci@nih.hhs.gov, info@smith4nj.com, marisa.kovacs@mail.house.gov, dmartin@tulane.edu, w.robinson@stanford.edu, tamir.elnabarawy@mail.house.gov, matt.hadro@mail.house.gov, collin.peterson@mail.house.gov, smithr@mmc.org, dennis.dixon1@nih.hhs.gov, estella.jones@fda.hhs.gov, monica.herman@mail.house.gov, mary.noonan@mail.house.gov, james.berger@hhs.gov, vanila.singh@hhs.gov, lise.nigrovic@childrens.harvard.edu, sdonta@comcast.net, wendyadams1@gmail.com, ptourad1@jhmi.edu, members@tulane.edu, kbechto1@jhmi.edu, jaucott2@jhmi.edu, cbb0@cdc.gov, RSabatino@LymeSocietyInc.org, NMurawsky@HRMML.com, Schutzer@gmail.com, stillman@cshl.edu, witkowsk@cshl.edu, gtrpaul@aol.com, corey.garry@mail.house.gov, travis.krogman@mail.house.gov, Alex.Azar@HHS.GOV, tickbornedisease@hhs.gov, andrew.dillon@nice.org.uk, nice@nice.org.uk, gillian.leng@nice.org.uk, paul.chrisp@nice.org.uk, Judith.Richardson@nice.org.uk, david.haslam@nice.org.uk, Phil.Fontanarosa@jamanetwork.org, Howard.Bauchner@jamanetwork.org, Rosa.Miranda@jamanetwork.org, Lisa.Hardin@jamanetwork.org, LetEd@jamanetwork.org, Alan_Kadish@nymc.edu, Kathryn_Brady@nymc.edu, Michelle_Cho@nymc.edu, Carol_Scavarda@nymc.edu, Donna_McKenna@nymc.edu
Date: February 9, 2019 at 9:42 AM
Subject: Efficacy of a 14-day course of amoxicillin for patients with erythema migrans
ScienceDirect
Diagnostic Microbiology and Infectious Disease
Efficacy of a 14-day course of amoxicillin for patients with erythema migrans.
https://www.sciencedirect.com/science/article/pii/S0732889318303304
Wormser GP1, Brady KC2, Cho MS2, Scavarda CA2, McKenna D2.
Excerpt:
“….findings provide additional evidence that a 14-day course of 500 mg amoxicillin given 3 times per day is highly effective therapy for patients with early Lyme disease.”
Feb 9, 2019
Division of Infectious Diseases,
New York Medical College,
Valhalla, NY 10595
Attn: Gary P. Wormser, MD
Dr. Wormser,
Once again, as previously stated in the email below; “Your fixation on the acute stage of disease [with bulls-eye rash] after early treatment has done nothing to advance our understanding of how Lyme disease disables its victim.”
Early treatment of strep throat prevents patients from advancing to rheumatic fever which as you know causes irreversible heart damage. If we focused on the acute stage of strep we would never have realized that missed early treatment caused serious life-altering/life-threatening health consequences.
-Ignoring the late stage horribly disabled Lyme population which could total in the millions worldwide.
I noticed that your manuscript did not include the following reference:
July 2017- In Vitro Susceptibility of the Relapsing-Fever Spirochete Borrelia miyamotoi to Antimicrobial Agents.
https://www.ncbi.nlm.nih.gov/pubmed/28674060
Excerpt:
“We were able to show that both B. miyamotoi strains and B. hermsii demonstrated greater susceptibility to doxycycline and azithromycin, equal susceptibility to ceftriaxone and proved to be resistant to amoxicillin in vitro as compared to the B. burgdorferi s.l. isolates.”
Your retirement Dr. Wormser is highy, highly anticipated.
Carl Tuttle
Lyme Endemic Hudson, NH
NOTE: Wormser’s study was funded directly from the US Centers for Disease Control
Funding: RO1 CK 000152 which appears to be an open checkbook for his junk science.
(Wasteful taxpayer spending)
Cc: Tick Borne Disease Working Group
Assistant Secretary for Health, ADM Brett P. Giroir, M.D.
On January 4, 2019 at 10:48 AM CARL TUTTLE <runagain@comcast.net> wrote:
JAMA
Shapiro ED, Wormser GP. Lyme disease in 2018: what is new (and what is not).
https://jamanetwork.com/journals/jama/article-abstract/2696480
Jan 4, 2019
Division of Infectious Diseases,
New York Medical College,
Valhalla, NY 10595
Attn: Gary P. Wormser, MD
Dr. Wormser,
In reference to your response to my letter to the Editor published in the December 18th issue of JAMA, it would appear that you and your coauthor Dr. Shapiro conveniently ignored my question highlighted below:
Excerpt from my letter to the editor:
Controversies About Lyme Disease
https://jamanetwork.com/journals/jama/article-abstract/2718786
-Carl Tuttle
“It is well known that untreated streptococcal pharyngitis can progress to rheumatic fever, causing irreversible heart damage. Untreated syphilis leads to progressive disability and dementia, and untreated HIV infection progresses to AIDS with significant disability and death. What happens to the patient with Lyme disease who goes months, years or decades before diagnosis because of a false negative serological test?”
Untreated Lyme is destroying lives, ending careers while leaving the patient in financial ruin as reported by the disabled Lyme community for the past three decades. The absence of a bulls-eye rash after tick bite allows patients to progress to severe neurological disease instead of obtaining a prompt diagnosis and early treatment.
I would like to call attention to the following quote taken from an interview with Professor Willy Burgdorfer, the discoverer of the Lyme disease spirochete:
“The controversy in Lyme disease research is a shameful affair. I say that because the whole thing is politically tainted. Money goes to people that have for the past thirty years produced the same thing. Nothing.” – Willy Burgdorfer
Source: (Live interview)
Prof. Willy Burgdorfer Talks About Lyme Disease
https://www.youtube.com/watch?v=dCnrUmAPcOE
Your fixation on the acute stage of disease after early treatment Dr. Wormser has done nothing to advance our understanding of how Lyme disease disables its victim.
For example:
Subjective symptoms after treatment of early Lyme disease.
https://www.ncbi.nlm.nih.gov/pubmed/20102996
Gary Wormser, New York Medical College
(Financed by the U.S. Centers for Disease Control)
RESULTS:
“At 12 months after enrollment, only 5 (2.2%) of 230 evaluable patients reported new or increased symptoms, and in none of the patients were these symptoms of sufficient severity to be functionally disabling”
_____________________________
Summary of Wormser’s study: Anyone experiencing symptoms after the one-size-fits-all treatment approach is just experiencing nothing more than the “aches and pains of daily living.”
So basically Wormser’s results are then assumed to apply to the entire patient population; in other words, Lyme is no big deal which has wrongly influenced our nation’s response to this serious life-altering health threat. The research into how Lyme disables should have been completed by now but the misclassification of Lyme as a simple nuisance disease (hard to catch and easily treated) has paralyzed the response to this runaway plague.
Many infections as I continue to point out evolve into an entirely different and serious life-altering/life-threatening disease when left untreated.
Post Treatment Lyme Disease Syndrome (PTLDS) after early treatment and untreated Lyme of months, years or decades are two entirely different disease states; the latter being ignored for three decades. Patients who have had a prolonged exposure to the pathogen are almost always incapacitated.
Purposely avoiding the advanced stage of disease hides the horribly disabled and anyone unable to see this is somewhat naive.
So I ask the question Dr. Wormser, What is the motivation for downplaying the severity of Lyme disease while ignoring patient outcry for thirty years?
A prompt response to this inquiry is requested.
Please hit Reply-All as I have carbon copied the Tick Borne Disease Working Group and Assistant Secretary for Health, ADM Brett P. Giroir, M.D.
Carl Tuttle
Lyme Endemic Hudson, NH
_________________
For more: