Archive for the ‘Treatment’ Category

Podcast: Evidence Supporting HCQ & Azithromycin for COVID-19

COVID-19 PODCAST: HYDROXYCHLOROQUINE AND AZITHROMYCIN FOR COVID-19 MAY BE EFFECTIVE AFTER ALL.

Hydroxychloroquine and azithromycin for COVID-19

Welcome to my next Inside Lyme podcast. – I will examine the evidence supporting hydroxychloroquine and azithromycin for COVID-19.

Podcast:

https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5idXp6c3Byb3V0LmNvbS83NzI

You may be wondering why I am discussing COVID-19 during an Inside Lyme podcast. I am concerned for my children, grandchildren, and my patients. I want to share my understanding of COVID-19 through my eyes as a clinical epidemiologist.

COVID-19 is now a pandemic. We need an effective and safe drug to treat this virus.

Researchers have turned to existing drugs that might be effective without causing significant side effects. Hydroxychloroquine and chloroquine have been prescribed for the treatment and prophylaxis of malaria in addition to the treatment of autoimmune diseases. Hydroxychloroquine and azithromycin have also been prescribed for Lyme disease patients. Hydroxychloroquine and azithromycin have been marketed under the name Plaquenil and Zithromax, respectively in the US.

Both chloroquine and hydroxychloroquine have side effects. The most common side effect of hydroxychloroquine is nausea and diarrhea. In rare cases, hydroxychloroquine can lead to reduced white blood cells, platelets count, anemia, and retinopathy. Retinopathy can lead to color blindness and loss of vision. Both hydroxychloroquine and azithromycin can lead to sudden death from a prolonged QT interval.

ANTIVIRAL EFFECTS OF HYDROXYCHLOROQUINE AND CHLOROQUINE

Hydroxychloroquine and chloroquine have shown some antiviral benefits in vitro (Wang, 2020, letter) Both have been studied for other related viruses, including Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (Mers).

Chloroquine improved outcomes in a series of small studies in China. Gao and colleagues discussed the finding in the journal BioScience Trends .

“Thus far, results from more than 100 patients have demonstrated that chloroquine phosphate is superior to the control treatment in inhibiting the exacerbation of pneumonia, improving lung imaging findings, promoting a virus negative conversion, and shortening the disease course according to the news briefing.”

These findings led the State Council in China to approve chloroquine for COVIID-19

Hydroxychloroquine and azithromycin for COVID-19 may be effective after all. CLICK TO TWEETUnfortunately, this series of Chinese trials do not appear to have been published. It is hard to discuss these Chinese trials until they are published.

FIRST FRENCH CLINICAL TRIAL BY GAUTRET AND COLLEAGUES

Gautret and colleagues published a French trial evaluating the benefit and risks of hydroxychloroquine and Zithromax for the treatment of COVID-19.

The authors prescribed 600 mg of hydroxychloroquine to 26 patients with COVID-19. Two were asymptomatic. Ten had upper tract respiratory infections, and six had lower tract respiratory infections. The doctors prescribed azithromycin to 6 of their patients with COVID-19 to prevent bacterial superinfection.

The authors were able to show a significant reduction in the viral load in nasopharyngeal samples of their COID-19 patients treated with hydroxychloroquine compared to COVID-19 patients who were not treated.

The authors were able to show even a greater reduction in viral load in the six COVID-19 patients when Zithromax was added.

Only one of the 26 patients treated with hydroxychloroquine was dropped from the study due to an adverse event. That patient dropped out due to nausea.

The authors explained why they decided to share their findings early.

“For ethical reasons and because our first results are so significant and evident, we decide to share our findings with the medical community, given the urgent need for an effective drug against SARS-CoV-2 in the current pandemic context.”

FLAWS IN THE FIRST FRENCH TRIAL BY GAUTRET

The Gautret trial was small and flawed. They should have used controls from the same hospital with the same characteristics as the 26 treated patients. Instead, they enrolled 16 controls were from other centers.

The Gautret trial did not evaluate whether a reduction or elimination of the COVID-19 virus in saliva would prevent outcomes important to patients such as a transfer to an intensive care unit or death. Four of the 26 patients treated with hydroxychloroquine did poorly. Three were transferred to the intensive care unit. One died. None of the patients with a COVID—19 infection developed a QT prolongation.

The Gautret trial was not designed to determine if the absence if COVID-19 from the saliva meant the absence of COVID-19 from other tissues.

The Gautret trial could not determine if the benefits seen for the six COVID-19 patients treated with azithromycin were from an antiviral effect or an antibiotic effect.

SECOND FRENCH TRIAL

A recently published second French trial by Gautret and colleagues added further support for the hydroxychloroquine with azithromycin.

“In 80 in-patients receiving a combination of hydroxychloroquine and azithromycin we noted a clinical improvement in all but one 86 year-old patient who died, and one 74-year-old patient still in intensive care unit.”

PLANNED TRIALS

Researchers at the University of Minnesota are planning on a trial “to see whether malaria treatment hydroxychloroquine can prevent or reduce the severity of the coronavirus disease (COVID-19)” writes Gabe Gutierrez and Dennis Romero in NBCNews.

COULD CUTTING THE COVID-19 VIRAL LOAD BE HELPFUL?

Yes, according to Gautret. “hydroxychloroquine and azithromycin “can play a role in controlling the disease epidemic by limiting the duration of virus shedding, which can last for several weeks in the absence of specific treatment.” write Gautret.

COULD HYDROXYCHLOROQUINE AND AZITHROMYCIN FOR INDIVIDUALS WITH COVID-19 BE HELPFUL?

Yes, according to both Gautret trials. Hydroxychloroquine and azithromycin lowered the COVID-19 viral load patient. Moreover, most of the patients with a COVID-19 infection were improved or discharged in the second Gautret trial.

COULD HYDROXYCHLOROQUINE AND AZITHROMYCIN PREVENT COVID-19 INFECTION?

Neither Gautret trials assessed whether hydroxychloroquine with azithromycin would be effective for prophylaxis before an infection. The study only enrolled hospitalized patients already infected with the COVID-19 virus.

WHAT NOW?

For now, researchers and politicians are divided on whether to recommend hydroxychloroquine and azithromycin for the prevention and treatment of COVID-19. There is growing pressure on doctors to wait for science.

Doctors have patients who are sick now. Doctors have patients who want to prevent getting COVID-19.

“The Food and Drug Administration (FDA) on Sunday issued an emergency-use authorization for a pair of anti-malaria drugs as health officials work to combat the rapid spread of the novel coronavirus.” writes Jusin Wise in The Hill.

Stay tuned.

References:
  1. Wang M, Cao R, Zhang L, Yang X, Liu J, Xu M, Shi Z, Hu Z, Zhong W, Xiao G. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 2020 Mar;30(3):269-271.
  2. Gautret P, Lagier JC, Parola P, Hoang VT, Meddeb L, Mailhe M, Doudier B, Courjon J, Giordanengo V, Vieira VE, Dupont HT, Honoré S, Colson P, Chabrière E, La Scola B, Rolain JM, Brouqui P, Raoult D. Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial. Int J Antimicrob Agents. 2020 Mar 20:105949.
  3. Cai J, Xu J, Lin D, Yang Z, Xu L, Qu Z, Zhang Y, Zhang H, Jia R, Liu P, Wang X, Ge Y, Xia A, Tian H, Chang H, Wang C, Li J, Wang J, Zeng M. A Case Series of children with 2019 novel coronavirus infection: clinical and epidemiological features. Clin Infect Dis. 2020 Feb 28. pii: ciaa198
  4. Gao J, Tian Z, Yang X. Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies. Biosci Trends. 2020 Mar 16;14(1):72-73.
  5. Gautret P, Lagier JC, Parola P, and colleagues. Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: an observational study. To be published as of 3/20/20.
  6. Clinical trials on coronavirus drugs may take only months, researcher says. Gabe Gutierrez and Dennis Romero, From NBCNew.com Last accessed 3/29/20.

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**Comment**

I posted this recently, but “authorities” have been bad-mouthing HCQ because many of them are getting financial kick-backs from Gilead Science, the manufacturer of the anti-viral Remdesivir, which bombed for Ebola, so they dug it out of the drug graveyard and are repurposing it for COVID-19.  HCQ is a direct competitor and the CDC/NIH won’t have it.  They diss any test or treatment that competes with their own.  It’s all about profits. This is why nothing will change until these people can not have patents and conflicting interests.  See:  https://madisonarealymesupportgroup.com/2020/05/08/update-cdc-playbook-learning-from-lyme/

When I compare how the media writes about the anti-viral drug Remdesivir vs HCQ, it isn’t surprising to learn that NIAID is working with Gilead to conduct Phase II human trials on on it.  Dr. Fauci, who is supposed to be a gate-keeper of public health, often does business with Big Pharma:  https://www.fort-russ.com/2020/04/shedding-light-on-the-dishonorable-record-of-dr-fauci-a-real-mengele/

Please see Dr. Eric Berg‘s FB video explaining HCQ vs Remdesivir:  https://www.facebook.com/135796882846/posts/10158628517062847/?sfnsn=mo&d=n&vh=e

Even the White House economic adviser got into a massive argument with Fauci over his ongoing resistance to the use of hydroxychloroquine to treat COVID-19:  https://madisonarealymesupportgroup.com/2020/04/08/peter-navarro-explodes-at-fauci-in-heated-showdown-over-hydroxychloroquine/

https://principia-scientific.org/a-tale-of-2-drugs-deep-state-chose-money-power-over-lives/

Excerpt:

Approximately $70 million in U.S. taxpayer funding began Gilead’s partnership with the U.S. Army, Centers for Disease Control and Prevention (CDC) and National Institutes of Health (NIH) to develop remdesivir. Initially for treating Ebola, it failed to show benefit and was shelved. If remdesivir is used to treat COVID-19, Gilead shareholders, not the taxpayers, will profit.

Early results of the first clinical trial of remdesivir against placebo in coronavirus showed modest benefits, according to The New York Times. Surviving patients given remdesivir were discharged four days sooner than patients given placebo, though no criteria were given for determining improvement. Death rates were not significantly different. About 25% of patients receiving remdesivir had potentially severe side effects, including multiple organ dysfunction, septic shock, acute kidney injury and low blood pressure. Another 23% showed evidence on lab tests of liver damage.

Gilead’s own press release revealed the side effect of acute respiratory failure in 6% of patients in the remdesivir five-day treatment group, and 10.7% of patients in the 10-day treatment group, clearly ominous findings with a drug designed to treat respiratory failure caused by COVID-19.

Dr. Steven Nissen, a Cleveland Clinic cardiologist who has conducted dozens of clinical trials, explained to The New York Times:

The disclosure of trial results in a political setting, before peer review or publication, is very unusual. Scientists will need to see figures on harms associated with the drug in order to assess its benefits. … This is too important to be handled in such a sloppy fashion.”

Going back to 1997, Donald Rumsfeld chaired the Board of Directors at Gilead and after 2001 he held share packages valued at $5-25 Million. Gilead originally developed Tamiflu. George P Shultz, US Secretary of State also was on the board. He sold stocks at a value of more than $7 million. CA governor’s Pete Wilson’s wife also sat on the board.

‘I don’t know of any biotech company that’s’ so politically well-connected [as Gilead],‘ Andrew McDonald, of the analyst firm Think Equity Partners, told Fortune.” (Source: “Virus Mania, How the Medical Industry Continually Invents Epidemics Making Billion Dollar Profits At Our Expense”)

It’s looking very much like the CDC is helping Gilead reclaim its losses on Remdesivir’s failure in Ebola.  Let’s just whip it back out for COVID-19, the public won’t notice!

For more:  https://madisonarealymesupportgroup.com/2020/05/11/what-are-sars-covid2-patients-really-dying-from/  Details are given within this link as to WHY HCQ works so well in COVID-19.  This is NOT a virus which causes interstitial pneumonia as we’ve been told, but rather it causes disseminated intravascular coagulation (DIC).  

https://madisonarealymesupportgroup.com/2020/04/04/efficacy-of-hydroxychloroquine-in-patients-with-covid-19-results-of-a-randomized-clinical-trial/

https://madisonarealymesupportgroup.com/2020/04/24/dr-oz-interviews-dr-didier-raoult-on-hydroxychloroquine-study-for-covid-19/

Dr. Zelenko, a New York doctor, has successfully treated 1,450 COVID-19 patients with a 99% success rate using a cocktail of hydroxychloroquine, Zinc Sulfate and Azithromycin:  https://techstartups.com/2020/04/21/dr-vladimir-zelenko-now-treated-1450-coronavirus-patients-2-deaths-using-hydroxychloroquine-99-99-success-rate-latest-video-interview/  Video with Zelenko in link.

https://madisonarealymesupportgroup.com/2020/04/08/peter-navarro-explodes-at-fauci-in-heated-showdown-over-hydroxychloroquine/

 

 

 

 

 

 

**UPDATE** CDC Playbook – Learning From Lyme

This article is an addendum to this: https://madisonarealymesupportgroup.com/2020/04/26/cdc-playbook-learning-from-lyme/.

Details revealing why the CDC and hospitals promote remdesivir (a.k.a. “The Fauci Death Protocol) and bad-mouths hydroxychloroquine, ivermectin, and natural remedies have now come to light.  Regarding the current state of science:

  • It’s been shown studies have been rigged for a pre-determined outcome
  • Some fraudulent studies have been retracted but many more remain.
    •  Dr. Didlier Raoult states the RECOVERY Trial was “the Marx Brothers doing science,” and that the person in charge of the trial (Professor Landray from Oxford) used the “usual” dosage for amoebic dysentery – which HCQ isn’t usually used for. He states that Landray does not understand anything about infectious diseases or anti-infection drugs, but led an international trial anyway.
    • A Yale epidemiologist is on record stating that Fauci is running a misinformation campaign against HCQ. 
    • Here’s another well written article picking apart the Big Pharma sponsored Together Trial being used to discredit cheap generic treatments. A complicit media then blasts out click bait headlines to an unsuspecting public.
    • This thorough article states that the trials for generic antivirals show systematic, egregious selection bias, as well as highlights the success in virtually eradicating COVID in countries who buck WHO instructions and used ivermectin prophylactically.

A doctor group has sued the FDA for ‘irrational’ interference of life-saving treatment, and got a partial win by a court order requiring the FDA to remove false claims about ivermectin.

Authorities gave the anti-viral drug remdesivir an emergency use authorization (EUA) while requiring two months of successful use of hydroxychoroquine in China and South Korea to get a similar EUA. We keep being told HCQ needs to be in a large double-blind placebo controlled study because it has scary side-effects, despite being used safely for decades – even over the counter!  The same is true for ivermectin.  Why are they suddenly dangerous?

Please know remdesivir, which is truly ineffective against COVID, has horrific side effects, including liver toxicity but is the “golden child” of authorities due to profits.  Here’s the facts:

  • There were more than 500 deaths in the first year of remdesivir usage.
  • There have been 20 deaths in 19 years of ivermectin usage.
  • A world famous toxicologist can not find a SINGLE case of an ivermectin overdose death.

Yet, according to a FOIA request that proved the CDC can not prove even ONE COVID death in children younger than 16, the FDA has now approved remdesivir for babies!  Here’s the facts:

  • Gilead, the manufacturer of remdsivir, announced by press release, (which appears to be the way science is now done in the ‘new normal) that there was clinical improvement at day 10.
  • The study conveniently has no control group, making it impossible to compare effectiveness against standard of care and only included 53 children – three of whom died
  • Adverse events were reported in 72% of the children, with 21% experiencing serious adverse events:
    • elevated levels of liver enzymes
    • allergic reactions
    • fever
    • shortness of breath
    • rash
    • nausea
    • sweating
    • shivering
  • The drug is marketed under the name Veklury, but the clincher is that similarly to the COVID injections which are in a current clinical study with those receiving the injections being test subjects, a clinical study on infants using Veklury is also underway and also will not be completed until 2023. Is it really wise to allow an out of control, corrupt, conflict-riddled government agency to use your child as a test subject?
  • This article goes through 5 studies the FDA uses to support remdesivir.  All of them show little if any benefit to hospitalized patients with moderate or severe disease.  It’s important to note that none of these studies looked at children or infants and only 8 subjects were under 18 – which means the FDA has ZERO data to support remdesivir in children.
  • And please see this article where France’s long-time vaccine policy chief delineates how COVID policy is “completely stupid” and “unethical,” and clarifies that hundreds of publications prove that early treatment works and how trials have been rigged.
Nitpicking and blackballing treatments is common with Lyme/MSIDS too.

In the case of COVID-19, severe patients can quickly die, making treatments desperately needed now, not in six months. One doctor has stated that Big Pharma’s suppression of ivermectin has cost 500,000 lives.

Doctors and pharmacists go to school to learn about drugs and their interactions. How about ‘authorities’ just let doctors do their jobs? I don’t see these ‘authorities’ condemning severely toxic cancer treatments which kill as many good cells as bad cells.

Why the focus on HCQ & ivermectin?

  • One good reason is its effectiveness not only against COVID but against other viruses as well.
  • Now, they’ve been found to be effective against cancer.
  • This recent article also explains another reason why.  In essence, the CDC is in bed with Gilead Science as nine of the experts on the NIH COVID-19 Panel recommending treatment options have disclosed financial support from Gilead
  • Gilead Science created the anti-viral remdesivir which was unsuccessful for Ebola. They then dug it out of the drug graveyard and pushed it for COVID-19 to make up for lost profits.
HCQ and ivermectin, even though they’re clinically showing great success, stand in the way of their chosen profitable treatment.
So there you have it.  This is what our authorities care about.  Profits.

Natural Supplements vs. Coronaviruses

 Approx. 46 Min.

Natural Supplements vs. Coronaviruses

Katy Wallace, Traditional Naturopath at Human Nature presents a webinar on natural supplements for immune system support.

https://humannaturellc.com/pages/about

Katy Wallace, ND RYT

Katy Wallace founded Human Nature in 2006. She holds a Doctor of Naturopathy (ND) degree from Trinity College of Natural Health and became a Certified Natural Health Professional (CNHP) in 2007. In addition to two years of coursework in traditional naturopathy, she apprenticed for over 1,500 hours as a nutrition consultant with a naturopathic clinic. There she cultivated a special interest in the use of food to address health issues. She has since expanded her knowledge of holistic nutrition into the field of functional medicine. She also holds a Master’s degree from the Institute for Environmental Studies at the UW–Madison and a Bachelor’s degree in Geology and Environmental Sciences from Carleton College in Minnesota. Katy is available for individual and family sessions, and she teaches the Body Tune‑up Workshop.
Katy is also a Registered Yoga Teacher and is certified in Kundalini yoga.

 

For more:  https://madisonarealymesupportgroup.com/2020/03/15/herbal-treatment-for-coronavirus-infections-buhner/

https://madisonarealymesupportgroup.com/2020/03/20/herbal-treatment-for-covid-19-addendum-buhner/

https://madisonarealymesupportgroup.com/2020/04/06/a-plausible-penny-costing-effective-treatment-for-corona-virus-ozone-therapy/

https://madisonarealymesupportgroup.com/2020/03/27/the-truth-about-hydroxychloroquine-plaquenil-in-the-treatment-of-covid-19/

https://madisonarealymesupportgroup.com/2020/04/07/covid-19-integrative-support-in-prevention-early-interventions/

https://madisonarealymesupportgroup.com/2020/03/12/convalescent-plasma-therapy-tested-on-critically-ill-covid-19-patients/

https://madisonarealymesupportgroup.com/2020/02/28/coronavirus-how-bad-can-it-get-includes-treatments-disulfiram-is-one/

https://madisonarealymesupportgroup.com/2020/02/13/washington-doctors-successfully-treat-coronavirus/

 

 

 

Seronegative for Bb Yet Doxy Successfully Treated PCMZL

https://www.ncbi.nlm.nih.gov/pubmed/32323885

2020 Apr 23. doi: 10.1111/pde.14165. [Epub ahead of print]

Primary cutaneous marginal zone lymphoma treated with doxycycline in a pediatric patient.

Abstract

We present the third reported case of a primary cutaneous marginal zone lymphoma (PCMZL) treated with doxycycline in a pediatric patient with negative serology for Borrelia burgdorferi. A 14-year-old boy presented with multiple asymptomatic erythematous papules and nodules on his extremities and trunk which biopsy confirmed to be PCMZL. He was started on doxycycline and experienced a near-complete response. Given the favorable side effect profile of doxycycline and the indolent nature of PCMZL, we believe doxycycline is a possible therapy for PCMZL pediatric patients who have widely disseminated cutaneous disease.

___________________

**Comment**

Anyone in the Lyme world understands that a negative serology result for Bb means absolutely nothing.  The fact this young man had “near-complete response” utilizing doxy as the sole treatment can pretty much bet he had Lyme/MSIDS.

For a good read (with pictures) on PCMZL:  https://www.dermnetnz.org/topics/cutaneous-marginal-zone-lymphoma

Excerpt:

It remains unclear whether cutaneous marginal zone lymphoma is the result of a de novo neoplastic process (the beginnings of a tumour) or a reaction to exogenous and/or endogenous agents [3]. A small number of cases have been associated with Borrelia burgdorferi (the cause of Lyme disease), and hepatitis C infection [1–4].

 

 

Love is Medicine Project – FREE May 21-27, 2020

https://loveismedicineproject.com/?  Register Here

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The Love is Medicine Project FREE and online from
May 21 – May 27, 2020

This is not the same world it was six months ago…

  • Isolation
  • Fear
  • Uncertainty

These are symptoms. Symptoms from a pandemic that has cast the world in fear.

A fear of getting sick, a fear of spreading the virus. We are ordered to hunker down, stock up on provision and wait…not sure of what will happen.

We are still waiting.

These events disconnect us from our routines, our environment, from others, even ourselves.

This is why now more than ever it is important to turn to self care.

How we love and care for ourselves and how we love each other.not only impacts disease but also resilience, depression and anxiety, sleep issues and performance. Self-care is the true healthcare!

The naturopathic philosophy honors what is called the Vital Force, that invisible force that guides all living things towards growth, betterment, compassion and healing. It is love. I believe health is our God-given birthright, our natural set point and that we are designed to thrive and heal, and are given everything in nature to do so.

I have embarked on an enlightening journey of Love is Medicine that will help you get back to feeling a sense of normalcy and who you really t are through practicing self-care and self-accountability, even in times of self-isolation.

On my journey, I have met with some of the greatest teachers and healers on the planet that don’t offer a one size fits all answer, but have led me to discover the healing ability within.
I will show you how we can choose to take back the reins from fate or genetics and we can rewrite our stories… and in this self-awareness, we learn, heal, adapt, and ultimately thrive.

In this documentary, you will learn:

  • How to increase resiliency and immunity
  • How to overcome anxiety and depression, even during times of physical distancing
  • Learning tools and strategies to cope in healthy ways
  • How we can heal through our mindset
  • How to heal your relationship with your environment
  • To discover new motivations that create the optimal environment for the emotional and physical health of you and your family
In these isolated times, we can pivot, adjust and evolve into something more.  Right now, love heals fear.
EPISODE 1: It’s NOT all in your Head
EPISODE 2:  How We Get Sick
EPISODE 3: Where Healing Comes From
EPISODE 4:  Healing the Past, Healing the Present
EPISODE 5: Self-Love & Loving Others
EPISODE 6:  The Body’s Wisdom
EPISODE 7:  Love is Medicine

 

Razi Berry is the founder and publisher of the journal Naturopathic Doctor News & Review, which has been in print since 2005, and the premier consumer-faced website of naturopathic medicine, NaturalPath. She is the host of The Natural Cancer Prevention Summit and The Heart Revolution-Heal, Empower and Follow Your Heart, and the popular 10 week Sugar Free Summer program.

From a near death experience as a young girl that healed her failing heart, to later overcoming infertility and Chronic Fatigue Syndrome and Fibromyalgia through naturopathic medicine, Razi has lived the mind/body healing paradigm. Her projects uniquely capture the tradition and philosophy of naturopathy: The healing power of nature, the vital life force in every living thing and the undeniable role that science and mind/body medicine have in creating health and overcoming dis-ease.

Follow Razi on Facebook at Razi Berry and join us at Love is Medicine to explore the convergence of love and health.