A Clinical Diagnostic System For Late-Stage Neuropsychiatric Lyme Borreliosis Based Upon An Analysis of 100 Patients

January 6, 2020

https://www.mdpi.com/2227-9032/8/1/13

A Clinical Diagnostic System for Late-Stage Neuropsychiatric Lyme Borreliosis Based upon an Analysis of 100 Patients

by Robert C. Bransfield^1,*, Dylan M. Aidlen², Michael J. Cook³ and Sagar Javia⁴

Healthcare 2020, 8(1), 13; https://doi.org/10.3390/healthcare8010013 (registering DOI)

Received: 8 December 2019 / Revised: 23 December 2019 / Accepted: 3 January 2020 / Published: 6 January 2020

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Many late-stage chronic Lyme disease clinical findings are neuropsychiatric. A total clinical assessment is critical in diagnosis, especially since controversy surrounds the reliability of laboratory testing. The clinical findings of one hundred Lyme disease patients with chronic neuropsychiatric symptoms were entered into a database. The prevalence of each clinical finding pre-infection and post-infection was compared and calculated within the 95% confidence interval. Patients had minimal symptoms pre-infection, but a high post-infection prevalence of a broad spectrum of acquired multisystem symptoms. These findings included:

impairments of attention span
memory
processing
executive functioning
emotional functioning
behavior
psychiatric syndromes
vegetative functioning
neurological
musculoskeletal
cardiovascular
upper respiratory
dental
pulmonary
gastrointestinal
genitourinary
other symptoms

The most prevalent symptoms included:

sustained attention impairments
brain fog
unfocused concentration
joint symptoms
distraction by frustration
depression
working memory impairments
decreased school/job performance
recent memory impairments
difficulty prioritizing multiple tasks
fatigue
non-restorative sleep
multitasking difficulties
sudden mood swings
hypersomnia
mental apathy
decreased social functioning
insomnia
tingling
word finding difficulties
name retrieval
headaches
sound hypersensitivity
paresis
anhedonia
depersonalization
cold intolerance
body temperature fluctuations
light sensitivity
dysfluent speech

The average patient had five symptoms pre-infection and 82 post-infection. Pattern recognition is critical in making a diagnosis. This study was used to develop three clinical assessment forms.

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**Comment**

A simple perusal of these symptoms reveals how insidious this complex disease is. This is not what authorities have been telling us Lyme causes. Lyme/MSIDS is a systemic illness that can affect every single organ of the human body – and often collectively. The idea that 21 days of an antibiotic are going to take care of this is pure comedy if you study it for any length of time at all. It is not uncommon for patients to see numerous specialists for the wide array of issues they must contend with.