This excellent video has Dr. Jane Marke discussing psychiatric illness in TBI patients, and while the technical lecture is given to psychiatrists it will be highly illuminating to patients. If you only want to know about psychiatric symptoms associated with Lyme, skip to around minute 28.
“Many doctors are convinced that after a short course of antibiotics patients should be well. The huge number of people still ill years after a course of antibiotics belie this assertion.”
http://www.janemarkemd.com/services-provided/lyme-psychiatry/ Her website states:
“Patients with Lyme, and related tick-borne disease, can have symptoms which mimic every known psychiatric syndrome. Treatment aimed directly at symptoms can relieve suffering rather quickly. These symptoms include insomnia, anxiety, “brain fog”, obsessive-compulsive symptoms, depersonalization, depression, and rages. But antibiotics are needed to undermine the root cause of the illness: the bacteria that causes Lyme: Borrelia burgdorferi.”
Other noteworthy comments:
15:12 – Marke describes the flagella of borrelia is more like the winged arms on a wine bottle opener which powerfully propels the organism.
15:40 – She questions if psychiatric disorders are inflammatory diseases. She lists: Autism, Alzheimer’s, Schizophrenia, Bipolar, PTSD, Depression, Stress, Sleep Deprivation, Self-harm, and Suicid Attempts. She also describes a study in England observing children for over a decade in which children with a high IL-8 at age 8 have an 81% change of developing depression by age 18 and a 2-fold chance of becoming psychotic.
18:04 – She states that TBI’s (Tick Borne Illness) causes an impaired Hypopituitary Axis (HPA) which on a chronic basis decreases cortisol and increases inflammation.
20:40 – Neurotoxins in the brain contribute to mental illness by causing problems with Homosysteine metabolism, which supresses remethylation, but that apoptosis (cell death) which can be reversed by supplementing with SamE.
21:30 – She says Post Treatment Lyme Syndrome (PTLS) is like a “dog whistle,” and usually demonstrates a bias on behalf of the authors who believe that 3 weeks of antibiotics cures LD. She then goes on to tell of a study that revealed that nearly 50% of those labeled as PTLS (with persistent symptoms) had anti-brain antibodies compared to 16.5% of Post Treatment Healthy Controls (no symptoms).
23:15 – She points out that the Lyme vaccine was taken off the market due to people getting sick from it not from “poor sales” as the cabal keeps saying. http://www.nytimes.com/2002/02/28/business/sole-lyme-vaccine-is-pulled-off-market.html
25:34 – Babesia and Bartonella are of extreme interest to psychiatrists.
*Bartonella produces most of the psychiatric problems as well as photophobia, floaters, blurred vision, bone pain, pain in the soles of the feet, headaches, the hallmark rash that looks like stretch marks, migratory polyneuropathy (burning, weakness, and numbness, on both sides of the body that moves around) and POTS (a fast heart-rate when one goes from a lying position to a standing position). Patients tend to exhibit OCD, self-mutilating behaviors, seizures, rage attacks, and psychosis (bipolar under this).
https://madisonarealymesupportgroup.com/2011/09/25/the-bartonella-checklist-copyrighted-2011-james-schaller-md-version-11/ Dr. Schaller’s Bartonella Checklist
*Babesia patients present with day/night sweats, severe fatigue, and low blood pressure and exhibit anxiety, panic disorders, and depression.
https://madisonarealymesupportgroup.com/2011/09/25/the-babesia-checklist-copyrighted-2011-james-schaller-md-mar-version-20/ Dr. Schaller’s Babesia Checklist
26:35 Persisting atypical and cystic forms drive local inflammation
28:23 Shows an excellent slide of the percentage of patients with late Lyme and various impairments such as Encephalopathy, memory issues, cognitive impairment, motor issues, and more.
31:15 She sites a study in which researchers set out to prove that there is no such thing as Late Lyme causing psychiatric problems. Compared to controls, chronic lyme patients met criteria for adult onset ADHD (both inattentive type and hyperactive/impulsive types combined) more frequently. She encourages doctors to take “syndromes,” and try to find an etiology, rather than the reverse, which is what is typically done. In this specific case, she’s asking doctors to question and try to find solid reasons (etiology) why an adult would all of a sudden have ADHD.
33:30 She says TBI patients are the worst sleepers she’s encountered. This is important because it is when toxins are cleared in the brain.
35:30 Depression is common in TBI patients.
36:50 She has an informative slide on suicides from those with Lyme collected from newspapers.
38:55 Shows a slide on Case studies of Intrusive Symptoms such as musical hallucinations, intrusive thoughts, Cognitive Tics, catastrophising, OCD.
40:00 Pediatric Auto-Immune Neurological Disorder (PANDAS) – caused by a lot of different organisms, including TBI’s, and it can also occur in adults. These folks do extremely well on antibiotics or Immunoglobulin. http://www.mercurynews.com/2014/04/19/misdiagnosed-bipolar-one-girls-struggle-through-psych-wards-before-stanford-doctors-make-bold-diagnosis-and-treatment/
41:00 Depersonalization, Violence, self-harm, and schizophrenia can be a part of the picture with TBI’s. At 41:20 she tells the story of a little girl who would throw horrific temper tantrums in which she would destroy her room and then feel absolutely horrible after the fact. She also had a psychotic episode. Her MSIDS testing came back flagrantly positive.
42:21 Autism – There is vertical transmission of Lyme from mother to fetus. Those with Bb in a study made remarkable improvement taking antibiotics.
42:56 Finding Spirochetes in Alzheimer’s patients as well as other pathogens.
45:18 She points out the CDC guidelines and controversies, including the very poor testing and the vilification of small labs. She recommends CLIA certified labs and that there is NO SUCH THING AS AN FDA APPROVED LAB. She recommends IGeneX labs as they report the bands to you and uses more than 1 strain of Bb.
For more on IGeneX: https://madisonarealymesupportgroup.com/2016/12/07/igenex-presentation/
48:17 She shows a SPECT scan with marked improvement after treatment with antibiotics for Encephalopathy. She also states that minocycline probably crosses the blood brain barrier the best.
49:02 is a slide with supplements that directly help detoxification, inflammation, and more. (vitamins, glutathione, LDN, herbs, diet, and compounds such as NAC, etc). For info on LDN: https://madisonarealymesupportgroup.com/2016/12/18/ldn/ and on NAC: http://www.lifeextension.com/magazine/2010/5/n-acetyl-cysteine/page-01
50:40 Marke asks psychiatrists with treatment resistant patients to consider microbes.
For more information on psychiatric Lyme: https://madisonarealymesupportgroup.com/2015/10/18/psychiatric-lymemsids/
For a great article for on-line counseling: https://www.ruschellekhanna.com/onlinetherapy