Archive for the ‘Transmission’ Category

Transmission of Bartonella Within Rhipicephalus Sanguineus: Data on Potential Vector Role of the Tick

https://pubmed.ncbi.nlm.nih.gov/33001978/

 
  • Bartonella henselae

The article also mentions that Rhipicephalus sanguineus, aka, the brown dog tick, kennel tick or pan tropical tick, (found worldwide) may also transmit Bartonella as it carries it. Further studies are needed to prove vector competence:

http://entnemdept.ufl.edu/creatures/urban/medical/brown_dog_tick.htm

For more:  https://madisonarealymesupportgroup.com/2016/01/03/bartonella-treatment/

Bartonella: How to Protect Yourself From This Stealthy Intruder

https://www.linkedin.com/pulse/bartonella-how-protect-yourself-from-stealthy-jill-c-carnahan-md/?

Bartonella: How to Protect Yourself From This Stealthy Intruder

Jill C. Carnahan, MD

Founder, Medical Director, Flatiron Functional Medicine
 

A walk through the woods. Playing with your cat. Getting a spider bite. These things might all seem unrelated, but they have one important thing in common – they can all potentially expose you to a sneaky and possibly dangerous bacteria known as Bartonella. 

This stealthy intruder can be dangerous and is notoriously hard to treat. Today we’re going to dive into exactly what Bartonella is. And most importantly we’re going to cover practical and simple ways you can protect yourself from this foreign invader. 

What Is Bartonella?

Bartonella is a type of bacteria that infects your cells – causing a condition known as bartonellosis. It’s estimated that there are over 20 different strains of Bartonella, and that at least 14 of them have the ability to be transmitted to humans.1 Once contracted, Bartonella makes itself at home, particularly in the cells that line your blood vessels and within your red blood cells.

What makes Bartonella unique is its ability to evade your immune system’s defenses. You see, Bartonella has a stealthy infection strategy that goes something like this:2

  1. Adhesion: Once contracted, Bartonella adheres to your red blood cells.
  2. Deformation: After attaching to your red blood cells, Bartonella gets to work on deforming the surface of your cells by creating progressive indentations and invaginations.
  3. Invasion: As the integrity of the surface of your red blood weakens, Bartonella begins its invasion – essentially hijacking your red blood cells.
  4. Persistence: Once your red blood cells are hijacked, Bartonella is able to evade your body’s defenses – allowing this bacteria to thrive and replicate undetected by your immune system.
  5. Suppression: Protected by the camouflage of your red blood cells, Bartonella is able to manipulate your immune system – triggering the secretion of certain chemical messengers that suppress and dampen your immune response.

Bartonella’s deceptive and stealthy infection strategy makes this pathogen particularly skilled at not only persisting and hiding within its host’s body – but it also creates ideal conditions for transmission. Let’s dive into exactly how this deceptive microorganism is transmitted and contracted.

How Do You Contract Bartonella?

Bartonella can be carried by most mammals, including domestic animals like cats, dogs, horses, and cattle. Typically, if you’re exposed to Bartonella, it’s through transmission from an animal. This can occur if you’re scratched by a cat or bitten by a dog. But it’s most often spread through a number of insect vectors such as:3

  • Ticks
  • Fleas
  • Lice
  • Sandflies
  • Red ants
  • Spiders
  • Bed bugs

These blood-sucking insects are the perfect vehicle for Bartonella to spread from host to host. 

What Are the Symptoms of Bartonella?

Bartonella can cause several identifiable conditions such as:4

  • Cat scratch disease
  • Carrion’s disease
  • Trench fever
  • Encephalopathy
  • Pericarditis
  • Chronic bacteremia

But Bartonella can also cause a handful of vague symptoms that are much more difficult to pinpoint, such as:5

Exactly how a Bartonella infection manifests varies substantially depending on the status of your immune system. And what makes this pathogen even trickier, is the fact that it’s often seen as a co-infection with other vector-borne pathogens.

Bartonella as a Co-infection: Its Link to Lyme Disease

The problem with ticks and other insect vectors is that they often harbor multiple infectious organisms. Meaning if you get bitten by a tick or other insect vector, you’re likely to be exposed and potentially infected with more than one organism – such as Bartonella. When multiple pathogens are contracted simultaneously, they’re called co-infections.

In particular, Bartonella has been identified as a co-infection to Lyme disease, the most common tick-borne disease. A co-infection with Bartonella has been found to significantly exacerbate symptoms associated with Lyme disease and can make diagnosis and treatment challenging. 

So let’s take a look at exactly how Bartonella can be addressed and if treatment can eliminate this persistent pathogen.

Is Bartonella Curable?

Because Bartonella is so good at being deceptive and camouflaging itself among your own cells, curing Bartonella requires a multi-faceted approach. So far, our best efforts at eradicating a Bartonella infection involves:6

  • A combination of prescription and herbal antimicrobials that kill off not only actively replicating forms of Bartonella, but also target “persisters” that have set up camp within your cells. These persisters aren’t actively replicating, but are hiding out in your cells and have the potential to replicate later on. 
  • Herbal and/or prescription medications that can break down the protective barrier some bacteria and viruses create, known as a biofilm
  • Supplements to decrease inflammation and support a healthy balance of cytokines and other chemical messengers that modulate your immune response.
  • Steps to boost and support your entire immune system.

Oftentimes treatment can take anywhere from 4-6 months or longer to improve the symptoms of Bartonella. Because Bartonella and other tick-borne illnesses can be difficult and time-consuming to treat, it’s imperative to take steps to protect yourself and your loved ones. 

So, How Can I Protect Myself Against Bartonella and Other Tick-Borne Diseases?

The best way to protect yourself against Bartonella and other tick-borne diseases is to take a two-pronged approach. Firstly, you’ll want to take precautions to prevent and avoid tick and insect bites. And secondly, you’ll want to bolster your natural defenses by ensuring your immune system is firing on all cylinders. Here are the steps I recommend taking: 

Protect Yourself From Tick and Insect Bites

If you’re going somewhere that may put you at risk of insect bites, take steps to protect yourself in the following ways:7

  • Stay on trails and avoid walking in tall grass or through the woods where you’re likely to come into contact with ticks and insects
  • Wear long pants and closed shoes
  • Use insect repellent
  • Wear lightly-colored clothes so you can more easily spot ticks or other insects on you
  • Inspect your clothes and hair and immediately remove any ticks or other insects

But the truth is it’s impossible to entirely avoid the possibility of being bitten by an insect vector that could potentially be carrying Bartonella or other infectious microorganisms. So it’s important to take these precautions in conjunction with the next step – boosting your immune system.

Give Your Immune System a Boost

Your immune system is your most powerful weapon against any and all potentially harmful microorganisms. And the good news is, you have a lot of control over how well your immune system functions. Some of the easiest and most effective ways to support your immune system are:

  • Eat an anti-inflammatory diet: The food you eat either promotes inflammation or fights inflammation. Basing your diet around anti-inflammatory foods minimizes inflammation – that way your immune system can direct all of its energy and resources at any potential threats. The basis of an anti-inflammatory diet is simply building most of your meals around real, whole foods and limiting processed foods. 
  • Take immune-boosting supplements: Supplements are a potent way to get a concentrated dose of immune-boosting nutrients and to fill in any nutritional gaps in your diet. Supplements like Gut Immune, Immune Booster, and Vitamin C help supercharge your immune system. If you want to learn more about how certain supplements boost your immunity, head over, and read my article covering the best immune-boosting supplements.   
  • Decrease your toxic burden: Our never-ending and ever-increasing exposure to environmental toxins can put a serious damper on your immune system. If toxins begin to accumulate in your body, it can overload your body’s detoxification mechanisms and essentially burn out your immune system. To learn exactly how you can begin decreasing your toxic burden and boost your immune system, check out my article How to Boost Your Immune System by Reducing Your Toxic Burden
  • Show your gut some love: The health of your gut and the status of your immune system are directly and intricately linked. If your gut is unhealthy, you’re guaranteed to have a weakened immune system. So taking steps to keep your gut healthy and happy is another surefire way to improve your immune system. To learn more about how your gut health impacts your immune system, you can read my article How to Heal Your Gut for a Stronger Immune System.

Your immune system truly is your best defense against any and all potentially harmful pathogens. Prioritizing the health of your immune system is hands-down one of the best things you can do for your overall health.

You Are Your Own Best Advocate

Bartonella is stealthy and deceptive – making it a particularly persistent and challenging infection to address. And the complications from this bacteria can be damaging and life-altering. So protecting yourself from this tricky microbe is crucial. 

And when it comes to protecting yourself from Bartonella, and other pathogens, you are your own best advocate. Following the steps outlined in this article is the best way to keep yourself safe and bolster your defenses. I always say that when it comes to your health, you are in the driver’s seat – and knowledge is your most powerful tool.

That’s why I’m dedicated to delivering the best and most up-to-date research to my patients and readers. If you want to access more empowering information about your health, my blogis chock-full of articles and resources. And if you want to take it even deeper, I encourage you to sign up for my newsletter. You’ll get all my best advice and resources delivered directly to your inbox. All you have to do is enter your name and email in the form below.

References

  1. https://rarediseases.org/rare-diseases/bartonellosis/
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255967/
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630881/
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC415619/
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630881/
  6. https://www.treatlyme.net/guide/kills-bartonella-a-brief-guide
  7. https://kidshealth.org/en/teens/lyme-risk-teen.html
 
 
 
While mainstream entomologists often deny or downplay tick and insect/arachnid transmission of Bartonella:  
 
 
 
 
Considering the severity of Bartonella, I’ve never understood why ‘authorities’ do not err on the side of caution regarding transmission of Bartonella by all insects and arachnids that feed on blood.  In my opinion, anything that feeds on blood should be suspect until proven otherwise.
 
Regarding persistence, Dr. Ericson has shown Bartonella to survive in tissues where a PIC line was removed:  https://madisonarealymesupportgroup.com/2019/02/27/advanced-imaging-found-bartonella-around-pic-line/
 
And mainstream medicine completely ignores the severe psychiatric manifestations that Bartonella can cause:  https://madisonarealymesupportgroup.com/2020/08/30/new-case-report-neuropsychiatric-symptoms-and-bartonella-associated-skin-lesions/
 

Possibility of Brown Dog Ticks Transmitting Bartonella to Humans

https://pubmed.ncbi.nlm.nih.gov/33001978/

Transmission of Bartonella henselae within Rhipicephalus sanguineus: Data on the Potential Vector Role of the Tick

Free article

Abstract

Bartonella henselae is a fastidious intraerythrocytic, gram-negative bacteria that causes cat scratch disease in humans. Ixodes ricinus (castor bean tick) has been confirmed to be a competent vector of B. henselae, and some indirect evidences from clinical cases and epidemiological studies also suggested that some other tick species, including Rhipicephalus sanguineus (brown dog tick, pantropical dog tick or kennel tick), may transmit the bacteria. B. henselae has been detected in R. sanguineus but no experimental investigations have been performed to evaluate the vector competency of this tick species regarding B. henselae transmission.

To this end, this work aimed to assess the transstadial transmission of B. henselae between larvae and nymphs of R. sanguineus as well as transmission by nymphs infected at the larval stage. Four hundred B. henselae negative larvae were fed with B. henselae-infected blood by using an artificial membrane feeding system.

After five days of feeding:

  • B. henselae was detected by PCR in 57.1% (8/14) of engorged larval pools
  • 66.7% (4/6) of semi-engorged larval pools
  • 66.7% (2/3) of larval feces pools
  • after molting, B. henselae DNA was also detected in 10% (1/10) of nymph pools, but not in tick feces
  • after a pre-fed step of nymphs infected at the larval stage on non-infected blood meal, B. henselae was detected by PCR in blood sample from the feeder, but no Bartonella colonies could be obtained from culture

These findings showed that B. henselae could be transstadial transmitted from R. sanguineus larvae to nymphs, and also suggest that these nymphs may retransmitted the bacteria through the saliva during their blood meal.

This is the first study that validated the artificial membrane feeding system for maintaining R. sanguineus tick colony. It shows the possibility of transstadial transmission of B. henselae from R. sanguineus larvae to nymphs.

_______________________

**Comment**

For decades now, ‘authorities’ have denied ticks can transmit Bartonella.  Since so many Lyme/MSIDS patients have Bartonella it’s always seemed highly likely to me that ticks play a role. This study adds to the growing body evidence that yes, in fact, ticks play a significant role.  For more:  https://madisonarealymesupportgroup.com/2020/09/02/bartonella-found-in-ticks-biting-midges-and-moose/

https://madisonarealymesupportgroup.com/2017/04/18/bartonella-vectors/

The other theory is that the tick’s ability to suppress the immune system reactivates a latent Bartonella infection already within the body.  Bartonella is prolific and can be obtained in many, many ways besides the bite or scratch of a cat:  https://madisonarealymesupportgroup.com/2016/01/03/bartonella-treatment/

To date, Bartonella isn’t even on mainstream doctor’s radar for those bitten by ticks. This must change.  Bartonella can be a severe, chronic infection that causes untold damage both physically and mentally.

Psychiatric issues and Bartonella:  https://madisonarealymesupportgroup.com/2020/08/30/new-case-report-neuropsychiatric-symptoms-and-bartonella-associated-skin-lesions/

Work is being done on the connection between Bartonella and cancer:  https://madisonarealymesupportgroup.com/2020/09/11/bartonella-is-an-entity-often-diagnosed-in-breast-imaging-department-during-axullary-lymph-node-assessment/

Bartonella can cause encephalitis:  https://madisonarealymesupportgroup.com/2020/07/30/bartonella-causing-encephalitis/

Great article showing the systemic manifestations:  https://madisonarealymesupportgroup.com/2019/04/24/human-bartonellosis-an-underappreciated-public-health-problem/

Two Exotic Disease-Carrying Ticks Identified in Rhode Island & First Case of Parasitic Soft Ticks Reported in New Jersey

https://www.sciencetimes.com/articles/27511/20200929/two-exotic-disease-carrying-ticks-identified-rhode-island.

Two Exotic Disease-Carrying Ticks Have Just Been Identified in Rhode Island

Sep 29, 2020

Local authorities in Rhode Island announced that two new tick species were identified on Block Island. The tick species were traced back to Eurasia and Asia origins.

Dr. Danielle Tufts from Columbia University identified the two species Haemaphysalis longicornis (Asian long-horned tick) and Haemaphysalis punctata (red sheep tick), reported the state’s Department of Environmental Management (DEM). (See link for article) 

Two Exotic Disease-Carrying Ticks Had Just Been Identified in Rhode Island

(Photo: Asian long-horned tick, adult female dorsal view climbing on a blade of grass – Photo by James Gathany; CDC)

____________________

**Comment**

Both ticks are considered live-stock pests but they can and do bite humans, transmitting diseases.  Farmers, hunters, and hikes are at greater risk.

  • The red sheep tick is identified with Tick paralysis, Tick Borne Encephalitis virus, Tribec virus, Bhanja virus, Crimean-Congo haemorrhagic fever virus, Babesia bovis, Theileria recondita, Coxiella burneti, Francisella tularensis.  http://www.bristoluniversitytickid.uk/page/Haemaphysalis+punctata/17/#.X3S-TS2ZOWgCattle: Babesia major, Babesia bigemina, Theileria mutans, Anaplasma marginale and Anaplasma centrale

    Sheep: Babesia motasi, Theileria ovis

H.-punctata-female-dorsal-0-300x225

Red sheep tick, Adult female dorsal view

https://medicalxpress.com/news/2020-09-jersey-1.html

Bat tick found for the first time in New Jersey

Bat tick found for the first time in New Jersey

A tick species associated with bats has been reported for the first time in New Jersey and could pose health risks to people, pets and livestock, according to a Rutgers-led study in the Journal of Medical Entomology.

This species (Carios kelleyi) is a “soft” . Deer ticks, which carry Lyme disease, are an example of “hard” ticks.

“All ticks feed on blood and may transmit pathogens (disease-causing microbes) during feeding,” said lead author James L. Occi, a doctoral student in the Rutgers Center for Vector Biology at Rutgers University-New Brunswick. “We need to be aware that if you remove from your belfry, attic or elsewhere indoors, ticks that fed on those bats may stay behind and come looking for a new source of blood. There are records of C. kelleyi biting humans.”  (See link for article)

___________________

**Comment**

A few important points:

  1. A related species, Carios jersey, was found in amber 2001
  2. C. kelleyi has been found in 29 states so far
  3. Public health risk remains unknown, but it has been found to be infected with harmful pathogens in other states
  4. There are reports of this tick feeding on humans
  5. The bat it feeds on regularly roosts in attics and barns
  6. It has been identified with rickettsia and borrelia (Lyme):  https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/carios
I can’t help but notice the bat connection, as well as the following:

https://www.newsbreak.com/news/2058858379813/first-case-of-parasitic-soft-ticks-reported-in-new-jersey  The current pandemic has been accompanied by cases of other illnesses and diseases such as African Swine Flu, Ebola, Bubonic Plague, West Nile Virus, Dengue outbreaks around the world.

Tick-borne Virus: All You Need to Know About the Disease That Has Killed 7 in China

https://economictimes.indiatimes.com/news/international/world-news/tick-borne-virus-all-you-need-to-know-about-the-disease-thats-killed-7-in-china/

Tick-borne virus: All you need to know about the disease that has killed 7 in China

**Comment**
While the world is fixated on COVID, there are other viruses that are deadly, and SFTS is one of them.
Important points:
  1. Symptoms include fever, coughing, thrombocytopenia (low platelets), leukcytopenia (love white blood cells), neurological issues and gastrointestinal disorders.
  2. SFTS has a 30% fatality rate.
  3. The Asian Longhorned tick appears to be the culprit which is now spreading across the U.S. ,despite the weather, by migrating birds.
  4. They don’t know if human to human transmission occurs.
  5. Since this was first isolated in 2011 you would think we would have better answers for something that kills 30% of the people it infects….

For more:  https://madisonarealymesupportgroup.com/2017/08/11/death-from-tick-borne-virus-sfts/  This article states the woman may have been infected by the bite from a cat.  If this is true, human to human transmission is highly probable.

https://madisonarealymesupportgroup.com/2018/09/12/three-surprising-things-i-learned-about-asian-longhorned-ticks-the-tick-guy-tom-mather/  We need answers on this tick fast because they line up on a blade of grass like a cluster-bomb.  Brush against it and you have hundreds if not thousands of ticks on you all at once.
And while researchers are quick to report it transmits Lyme disease rarely, it’s still a possibility:  https://madisonarealymesupportgroup.com/2019/10/26/researchers-conclude-asian-longhorned-tick-contributes-minimally-to-lyme-disease-in-the-u-s/
uninfected H. longicornis larvae could acquire B. burgdorferi s.s. while feeding on infected Mus musculus mice (infection prevalence >50% in freshly fed larvae) but that the infection was lost during the molt to the nymphal stage. None of 520 tested molted nymphs were found to be infected, indicating that transstadial passage of B. burgdorferi s.s. is absent or rare in H.
This tick should be a grave concern to all of us.