Archive for the ‘research’ Category

Cancer, MS, And Repurposed Drugs

For a video that ties much of this together, listen to Dr. Lee Merrit discuss cancer and COVID and the success of anti-parasitic medications.  Go here for a brief summary, but take the time to listen to Merrit.

Lyme/MSIDS patients have already been warned by Dr. McDonald that there is a connection between Lyme and cancer.  Now, with new Turbo cancers on the rise, it’s more important than ever to have effective treatments.  The establishment has essentially failed again in treating this monster and doctors/researchers that have had success are “disappeared.”  

https://justusrhope.substack.com/p/celebrity-beats-stage-4-cancer-with

Celebrity Beats Stage 4 Cancer with Repurposed Drugs

Fenbendazole Cocktail Gets the Credit

 
JUSTUS R. HOPE
FEB 5, 2024
 
Article Excerpts:

When Captain Kevin Hennings, Florida Keys Fishing Guide to the Stars, contracted Stage 4 Colon Cancer, his world collapsed.

He tells his story to comedian Jim Breuer between fits of laughter about how he went from a televised celebrity to a dying patient, and how he now has become a better person for it.

He shared the dire news with his wife and family, and they supported his decision to undergo the conventional treatments of surgery, radiation, and chemotherapy. While the official 5-year survival rates are around 13%, Kevin fought the cancer like he would fight a military opponent – to beat it.

Unfortunately, sometime in September of 2021, despite three years of grueling chemotherapy, his medical team informed him that he was going to lose the battle. They told him to begin hospice and prepare for the worst, as they had no further treatment options.

His spiritual sister explained that an acquaintance from church had a friend with Stage 4 colon cancer who had opted out of chemotherapy. Instead, he took Fenbendazole, an antiparasitic agent. And she explained, he fully recovered.  (See link for article and interview)

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https://www.mdpi.com/2673-4087/4/3/19

The Probable Infectious Origin of MS

by 1,2 and 1,2,*

NeuroSci 2023, 4(3), 211-234; https://doi.org/10.3390/neurosci4030019
Submission received: 18 July 2023 / Revised: 17 August 2023 / Accepted: 25 August 2023 / Published: 7 September 2023

Abstract

Multiple sclerosis (MS) is an immune inflammatory disease that causes demyelination of the white matter of the central nervous system. It is generally accepted that the etiology of MS is multifactorial and believed to be a complex interplay between genetic susceptibility, environmental factors, and infectious agents. While the exact cause of MS is still unknown, increasing evidence suggests that disease development is the result of interactions between genetically susceptible individuals and the environment that lead to immune dysregulation and CNS inflammation. Genetic factors are not sufficient on their own to cause MS, and environmental factors such as viral infections, smoking, and vitamin D deficiency also play important roles in disease development. Several pathogens have been implicated in the etiology of MS, including Epstein–Barr virus, human herpesvirus 6, varicella-zoster virus, cytomegalovirus, Helicobacter pylori, Chlamydia pneumoniae, and Borrelia burgdorferi. Although vastly different, viruses and bacteria can manipulate host gene expression, causing immune dysregulation, myelin destruction, and neuroinflammation. This review emphasizes the pathogenic triggers that should be considered in MS progression.

https://justusrhope.substack.com/p/ivermectin-cancer-study-begins?

Ivermectin Cancer Study Begins

Observing the Effects of Ivermectin on Turbo Cancers

 
JUSTUS R. HOPE
FEB 2, 2024
 

Dr. Harvey Risch, one of the world’s most esteemed epidemiologists, has stated that Turbo Cancers represent a new and different type of condition. For example, Dr. Risch explains that the sudden development of colon cancer in a young person with no known family history means that something completely novel is now happening to cause this.

Dr. Harvey Risch is a Professor Emeritus of Epidemiology at Yale University.

“Cancer as a disease takes a long time to manifest itself from when it starts, from the first cells that go haywire until they grow to be large enough to be diagnosed or to be symptomatic, can take anywhere from two or three years for the blood cancers, like leukemias and lymphomas, to five years for lung cancer, to 20 years for bladder cancer, or 30, 35 years for colon cancer, and so on.”

We know that colon cancers usually take decades to develop and begin with an adenomatous polyp. This polyp slowly undergoes malignant transformation under carcinogenic conditions – which might involve insulin resistance, diabetes, damage to mitochondria, an altered gut microbiome, lack of exercise, and an inflammatory diet. The cancer expands to gradually invade the mucosal wall, and then the surrounding tissues and lymph nodes. By the time this all plays out, the person is usually in their 50s or 60s.

In the rare cases of genetic colon cancer, like Familial Adenomatous Polyposis (FAP) or Hereditary Non-polyposis Colorectal Cancer (HNPCC), it can occur in young people. However, we are now seeing full-blown non-genetic colon cancers develop suddenly in 20, 30 and 40-year-olds in large numbers which is unprecedented.  (See link for article and video)

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**Comment**

Dr. Marik has taken the lead in using repurposed drugs which is why he has been heavily censored – especially about ivermectin, a cheap, safe, and effective COVID treatment, which just happens to also be working for cancer.  Go here for more, particularly about the responsive cancer types; however, Ivermectin has shown some degree of anti-cancer effect in every cancer type it has been tested on.

  • Two French researchers found that ivermectin could reverse multidrug resistance in tumors all the way back in 1995.
  • The drug targets tumor stem cells—a driver of cancer tumors and relapses—and promotes cancer death.
  • It enhances the effects of chemo and radiation therapy. It has a broad impact on the immune system, increasing immune offense against cancers.
  • It inhibits cancer cell cycles, helping prevent the formation of new cancer cells.
  • It promotes the killing of cancer cells by inducing mitochondrial stress and prevents cancer survival by preventing new blood vessels, which transport energy and fuel to cancers, from forming near cancer cells.
Dr. Peter P. Lee’s team has begun a clinical trial of ivermectin combined with the immunotherapy drug Pembrolizumab for women with metastatic breast cancer. They have also found ivermectin to be effective against other types of cancer cells. Therefore, additional patients may be included in future trials.  The interaction of the two therapies is a highly complex process dependent on timing, dosage, and drug combinations.

Marik and Dr. Kathleen Ruddy are undertaking an observational study which involves repurposed drugs and metabolic treatments for patients with advanced cancers. Ruddy has observed amazing results using ivermectin against a variety of malignancies. The new study will look at dose, timeline of administration and response to treatment.

Patients will determine the specific repurposed drugs and interventions they want and could include the following with or without traditional cancer treatments:

  • Mebendazole
  • Metformin
  • Vitamin D
  • Fish Oil
  • Curcumin
  • Green Tea
  • Melatonin
  • sunlight
  • overnight fasting
  • a ketogenic diet
  • daily resistance 
  • aerobic exercise

Expect Marik and Ruddy to be vilified as quacks. It’s what Big Pharma and its subsidiaries do to those who dare to color outside the lines. Just remember what they did to ivermectin, HCQ and those who dared to prescribe them:

Also see:  

Category:

Activism, Cancer, research, Treatment

Winter Ticks Threaten Moose

https://oodmag.com/winter-ticks-threaten-moose/

Winter ticks threaten moose

by Matthew Robbins | January 22, 2024

Across this province and beyond, ticks are an increasingly troublesome reality for sportsmen and women. These little bloodsuckers are more than just annoying — they carry a host of ailments to which outdoor enthusiasts are especially vulnerable. Along much of their southernmost range, moose are struggling to adapt to the growing influence of ticks, and Ontario is no exception.

Tick troubles

By and large, human-tick encounters involve one of two species: the dog tick (aka wood tick) or the black-legged tick (aka deer tick), the latter of which is responsible for a rising incidence of Lyme disease in humans. Despite their increasing prevalence, however, neither of these species appear to be an issue for moose.

Instead, the trouble for our iconic forest-giant comes almost exclusively from Dermacentor albipictus, otherwise known as the winter tick. These pesky parasites are slightly larger than other species of North American ticks and are considered unique for their use of a single host-animal. While most species of tick switch hosts during their various life stages, winter ticks catch a ride on an unsuspecting ungulate as larvae and remain there until the swollen females are ready to drop to the forest floor, lay their eggs, and die.  (See link for article)

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**Comment**

Obviously, such a long feeding by upwards of 40,000 ticks on a singular moose will cause severe blood loss, emaciation, and anemia.  

These poor, plagued moose will rub on trees rubbing their hair off leaving them grey earning them the title “ghost moose.”

The article then predictably pushes the ‘climate change’ propaganda, blaming warmer winters for tick explosions, when independent research has shown this notion to be false.  Nobody seems to ever mention our government’s involvement of experimenting and dropping ticks from airplanes.

More specifically, in this link is a 1967 U.S. Army report, on page 600 that shows that ticks were experimentally infected with various pathogens.  For instance, on page 301 Boophilus australis was experimentally infected with murine typhus rickettsia.  Dermacentor albopiotus (the exact winter tick affecting moose) with spotted fever, Dermacentor andersoni with typhus rickettsiae, and so on and so forth.  The link to the army report is conveniently broken (censored) as it incriminates our own government and military.

It’s just easier to blame the climate boogey-man.

Sadly, 90% of moose calves will die due to this blood-letting.

Category:

Lyme, research, Ticks, Transmission

Deciphering Lyme Disease

https://www.harvardmagazine.com/2024/01/right-now-lyme-disease

Deciphering Lyme Disease

by Jonathan Shaw

JANUARY-FEBRUARY 2024

WHOLE-GENOME sequencing of hundreds of samples of Borrelia burgdorferi, the tick-borne bacterium that causes Lyme disease, has revealed why the severity of the illness varies from place to place and person to person. The findings suggest new strategies for diagnosis, treatment, and prevention of Lyme—the most prevalent vector-borne disease in North America and Europe, and one of the fastest-growing infectious diseases in the United States.

Assistant professor of medicine Jacob Lemieux spearheaded the sequencing effort beginning in 2017. Lemieux had become interested in tick-borne disease several years earlier, when he was a postdoctoral researcher in the lab of professor of immunology and infectious diseases Pardis Sabeti. A colleague had mentioned the genetic similarities between the parasites that cause babesiosis (a disease also spread by ticks) and malaria, which Lemieux had studied previously. Intrigued, he and Sabeti, one of the world’s leading geneticists studying the biology and evolution of human disease, published the whole-genome sequence of the Babesia parasite in 2015.

On the heels of that success, they expected their sequencing of Lyme-causing bacteria to take perhaps six months. “It took more like six years,” says Lemieux. “It turned out that the genetic diversity of Lyme disease is orders of magnitude harder to handle than any other pathogen.” And that complexity is associated with the wide range of Lyme disease symptoms—from severe arthritis in children to fatigue and potentially debilitating joint, neurological, and cardiovascular symptoms in adults—that persist in some patients for months or even years after treatment.

Rather than being concentrated in one place, “The genome of the Borrelia spirochete [it is a spiral-shaped bacterium] is shredded,” he explains. “There is one chromosome,” the double-stranded linear sequence of DNA found in most living cells, “but then there are about 20 plasmids.” Plasmids are small, circular strands of DNA that can replicate independently of the DNA in the main chromosome. And though extremely difficult to sequence, they turned out to be critical to understanding variations in the severity of Lyme disease.  (See link for article)

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A few key points:

  • Patient samples were primarily from those with the “classic” bullseye rash, which while diagnostic of Lyme is highly variable and often not seen at all in many patients.
  • The group focused on strains that disseminate easily.
  • A study author who also studies COVID states BOTH diseases have plasmids that used to be viruses that infected bacteria.
  • Notably, the most severe cases had a surface protein with plasmids that occur only in certain strains that are associated with virus-derived plasmids. Some of the genes encode lipoproteins on the bacterial surface which appear to protect the bacteria against immune assault.
  • The authors state their discovery will allow for better diagnostic tests that can single out those at risk of severe disease, which could in turn help researchers test whether longer treatments are more effective against these more dangerous strains.
  • Predictably, the group is pushing for a “vaccine” to “block” the illness from ever occurring.
  • The team included none other than Allen Steere who first identified the disease affecting children in Lyme, Connecticut that he wrongly attributed to juvenile arthritis. His continued myopic focus on Lyme arthritis is worth noting as the disease(s) in the literature has shown it to cause dermatological, neurological, and neuropsychiatric manifestations since the 1800’s. He was also named in the racketeering lawsuit alleging he colluded to deny persistent infection. He is a pharma consultant, co-author of the antiquated and unscientific IDSA Lyme guidelines and a CDC/EIS biowarfare officer which is chartered with responding to biowarfare agents released on U.S. soil, as well as developing vaccines against them. He also worked for the private Yale Corporation that worked closely with the biowarfare tick lab in Connecticut. Steere personally oversaw the Lymerix vaccine trials and associated tests run by the company that licensed the vaccine from his previous employer.  Steere personally testifies against doctors who who treat chronic Lyme.  Source

Category:

Lyme, research, Testing, vaccines, Viruses

Decoding the Mysteries of Medically Unexplained Neurologic Diseases

https://www.rutgers.edu/news/decoding-mysteries-medically-unexplained-neurologic-diseases

Decoding the Mysteries of Medically Unexplained Neurologic Diseases

By Greg Bruno

Date  January 10, 2024

Using advanced research techniques, Rutgers Health–led scientists have shed light on how chronic fatigue syndrome and fibromyalgia are related, paving the way to even bigger breakthroughs.

New research may create some respite for sufferers of two medically unexplained fatigue-inducing conditions: myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and fibromyalgia (FM).

The conclusion, and the methods used to reach it, could inform how these and other conditions – such as multiple sclerosis, long COVID, Alzheimer’s and post-treatment Lyme disease – are diagnosed and treated.

“Using mass spectrometry to analyze spinal fluid, the liquid that bathes the brain, we found that these two illnesses may fall along a common disease spectrum,” said Steven Schutzer, a professor of medicine at the Rutgers New Jersey Medical School and lead author of the study published in the Annals of Medicine.

“The results have implications for how the conditions can be investigated, while the technique may help advance treatment approaches with these diseases, and many others,” Schutzer said.

(See link for article)

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**Comment**

Due to advances in mass spectrometry, of 2,083 proteins quantified, 1,789 proteins were present in both samples of ME/CFS and fibromyalgia, and only ME/CFS, indicating there is a relationship between the two diseases.

For more:

Category:

Inflammation, Lyme, research

Big Pharma: Influences Diagnoses & Treatments & More Than Half of CDC Employees End Up Working For It

https://thevaccinereaction.org/2024/01/pharma-influences-diagnoses-and-treatments-in-bible-of-psychiatric-disorders/

Pharma Influences Diagnoses and Treatments in “Bible” of Psychiatric Disorders

by Barbara Cáceres

Published January 16, 2024

Article Excerpts:

A new study published in the British Medical Journal (BMJ) found that 55 of the 92 American doctors who determine what diagnoses and treatments are included in the American Psychiatric Association’s (APA) most recent edition of their Diagnostic and Statistical Manual (DSM) collectively received more than $14 million in previously undisclosed industry funding.1

The APA’s manual is often referred to as the “bible” of psychiatric disorders because of its enormous influence on clinical practice, affecting such disparate domains as jurisprudence and insurance claims. The APA also produces and disseminates clinical-practice guidelines directly tied to DSM diagnoses.2  The DSM’s fifth edition, the DSM-V, was published in May 2013; a text revision was published in March 2022 as the DSM-5-TR.

Transparency is Not the Answer

After the 1994 release of DSM-4, the APA instituted a policy requiring expert advisors to disclose drug industry ties. But the move toward transparency did little to cut down on conflicts of interest, with nearly 70 percent of DSM-5 task force members reporting financial relationships with pharmaceutical companies—up from 57 percent for DSM-4.7

(See link for article)

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A few points:

  • The study used info only from Open Payments which doesn’t include payments to doctors based outside the U.S. so the problem is worse.
  • Panel members with Pharma ties have introduced new diagnoses and revisions to treatment which have lacked scientific evidence but helps industry.
  • In 2019, 1 in 6 Americans over age 18 took medication for a psychiatric disorder.
  • The Institute of Medicine (IOM) is recommending that only independent experts without commercial ties be involved in clinical guideline decision-making.
One would hope this last point would be common practice, but alas, it isn’t.
As always, “Follow the money.”

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https://thevaccinereaction.org/2024/01/more-than-half-of-cdc-employees-end-up-working-for-pharma/

More Than Half of CDC Employees End Up Working for Pharma

by TVR Staff

Published January 14, 2024

Article Excerpts:

A study conducted by researchers at the University of Southern California (USC) and Harvard University and published in the journal Health Affairs found that 54 percent of the staff members, who were employed at the U.S. Centers for Disease Control and Prevention (CDC) and left the federal health agency during 2004-2020, went on to work for the pharmaceutical industry.1 2 3

According to the study:

Exiting staff went to not only biopharmaceutical and device manufacturers, but also health insurers, information and communication technology firms, real estate firms with medical property portfolios, and consulting firms.1

Current Laws and Regulations Have Little Impact on CDC/Pharma Conflicts of Interest

Current federal laws and regulations, which were supposed to reduce conflicts of interest that arise from the revolving door between the CDC employees and pharma, do not appear to adequately address the “pre- and post-departure risks.” Study authors Kanter and Carpenter cited 18 U.S. Code Section 207, which imposes a one- to two-year “cooling-off period” on former officials within the executive branch of the federal government and prohibits them from lobbying the government on behalf of private organizations.1 3

Kanter said that the cooling off period laws “do not cover much lobbying related to federal agency decision making, like regulations and drug authorizations, so they don’t necessarily deter that behavior.”3

Revolving Door Between CDC and Pharma a Serious Problem

The “sheer scale” of the revolving door between the CDC and other DHHS agencies, such as the U.S. Food and Drug Administration (FDA), is apparently serious enough that Kanter and Carpenter described it as a “troubling” and one that “merits further scrutiny.”1

For  more:

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**Comment**

Speaking of treatment “guidelines” and sordid history, investigative journalist Kris Newby uncovered the fact that a majority of those determining the Lyme treatment guidelines also had financial conflicts of interest with Big Pharma.

It’s important to note that these guidelines have remained frozen in time for over 40 years despite new science and reality.  This of course means the controversy continues making doctors too frightened to treat patients and depart from the accepted narrative.

Category:

Activism, Psychological Aspects, research