Archive for the ‘Treatment’ Category

Bartonella Presenting with Lymphadenopathy

Cat-Scratch Disease in an AIDS Patient Presenting with Generalized Lymphadenopathy: An Unusual Presentation with Delayed Diagnosis.

Mantis J, et al. Am J Case Rep. 2018.


BACKGROUND Bartonella infection is the causative organism of cat-scratch disease (CSD), which typically presents with self-limited localized lymphadenopathy. In HIV-infected patients, Bartonella infection can cause systemic illnesses with significant morbidity and mortality manifesting as bacillary angiomatosis (BA), hepatic peliosis, splenitis, bacteremic febrile illness, and other organ involvement. To the best of our knowledge, there have been no reports of HIV-infected patients presenting with generalized lymphadenopathy caused by Bartonella infection. We report an unusual case of CSD presenting with generalized lymphadenopathy in an AIDS patient with advanced immunosuppression.

CASE REPORT A 44-year-old woman with AIDS, advanced immunosuppression, and intermittent adherence to antiretroviral therapy and medical care, presented with cough and increased generalized tender lymphadenopathy. A lymph node biopsy 1 year earlier was non-diagnostic for tuberculosis, fungal infection, and lymphoproliferative disorders. She remained with generalized lymphadenopathy. A repeat biopsy with the addition of Warthin-Starry silver staining suggested the diagnosis of cat-scratch lymphadenitis. She responded well to a long course of azithromycin antibiotic therapy, with the resolution of lymphadenopathy. CONCLUSIONS Cat-scratch disease may present with prolonged generalized lymphadenopathy, an unusual presentation in HIV patients with advanced immunosuppression. Awareness of the possibility of CSD in a similar clinical scenario may prompt early recognition and management of this disease.



While this case study is on an HIV-infected patient, those infected with Lyme/MSIDS can have similar presentations with systemic illness, and significant morbidity and mortality due to the immunosuppressive nature of tick borne infections (TBI’s).

Both my husband and I had Bartonella yet no lymph-node involvement.  This checklist outlines most of the most prevalent symptoms & we had many:  (Checklist within link along with other symptoms and cases)

Notice that treatment was a “long course” of antibiotics that for some reason is acceptable for an immunosuppressed HIV patient but NOT an immunosuppressed Lyme/MSIDS patient.  It’s a head scratcher for sure.

Congenital transmission is highly likely:


High Prevalence, Diversity, & Coinfection of Bartonella in Saudi Arabian Gerbils

Molecular assessment of Bartonella in Gerbillus nanus from Saudi Arabia reveals high levels of prevalence, diversity and co-infection.

Kleynhans DJ, et al. Infect Genet Evol. 2018.


Bartonellae bacteria are associated with several re-emerging human diseases. These vector-borne pathogens have a global distribution, yet data on Bartonella prevalence and diversity in the Arabian Peninsula are limited. In this study we assessed the Bartonella infection status of the Baluchistan gerbil (Gerbillus nanus), a species associated with pastoral communities throughout the Middle East region, using a multi-gene PCR screening approach.

The results demonstrated that 94 (68.1%) of the 138 gerbils trapped on a monthly basis, over a period of one year, were PCR-positive. Sequencing of the gltA gene region confirmed the presence of four discrete Bartonella lineages (I-IV) and high levels of co-infection (33.0%). Each of the four lineages, varied in overall abundance (7.5%-47.9%) and had discernible seasonal peaks. Bartonella status was significantly correlated with ectoparasite presence, but not with sex, nor with season. Statistical analyses further revealed that co-infected individuals had a significantly higher relative body condition. Multi-locus sequence analysis (MLSA) performed with a concatenated dataset of three genetic loci (gltA, nuoG, and rpoB), 1452 nucleotides (nt) in length confirmed that lineage IV, which occurred in 24 PCR-positive animals (25.5%), is most closely related to zoonotic B. elizabethae. The remaining three lineages (I-III) formed a monophyletic clade which, on the basis of gltA was shown to contain bartonellae from diverse Gerbillinae species from the Middle East, suggestive of a gerbil-associated species complex in this region. Lineage I was identical to a Candidatus B. sanaae strain identified previously in Bushy-tailed jirds (Sekeetamys calurus) from Egypt, wherease MLSA indicate that lineages II and III are novel. The high levels of infection and co-infection, together with the presence of multiple Bartonella lineages indicate that Gerbillus nanus is likely a natural reservoir of Bartonella in the Arabian Peninsula.



Bartonella is highly prevalent in Lyme/MSIDS patients, yet, mainstream medicine isn’t even looking at it.  If they do look at it they make the mistake of downplaying its significance.  This article is yet another example of its proliferation and presence.  Ticks are also ectoparasites yet many deny its ability to transmit Bartonella.  This issue needs to be resolved; however, since so many Lyme/MSIDS patients have it, it’s either transmitted directly from ticks OR the tick bite and subsequent immune suppression causes asymptomatic cases to reactivate.  Either way, it is an important issue.  Fifteen species of gram-negative aerobic Bartonella are known to infect humans; however Dr. Ricardo Maggi’s statement is quite telling, “This case reinforces the hypothesis that any Bartonella species can cause human infection.”  If you suspect Bartonella, print off and fill out this checklist.  While the symptoms are many and varied, my husband had unexplained and sudden anxiety, irritability, rage, sudden knee-jerk reactions, skin tags & severe itching, and we both felt as if someone beat the bottoms of our feet with a hammer.  Proper treatment ameliorated all of these symptoms.

Wahls Protocol – Impact of Diet & Nutrition in MS & Other Neurological Diseases

Episode #87: Wahls Protocol with Dr. Terry Wahls, MD

By Better Health Guy

Why You Should Listen:

In this episode, you will learn about the Wahls Protocol and the impact of diet and nutrition in MS and other neurological diseases.

About My Guest: My guest for this episode is Dr. Terry Wahls. Terry Wahls, MD is an Institute for Functional Medicine Certified Practitioner and a clinical professor of medicine at the University of Iowa where she conducts clinical trials. In 2018 she was awarded the Institute for Functional Medicine’s Linus Pauling Award for her contributions in research, clinical care, and patient advocacy. She is also a patient with secondary progressive multiple sclerosis, which confined her to a tilt-recline wheelchair for four years. Dr. Wahls restored her health using a diet and lifestyle program she designed specifically for her brain and now pedals her bike to work each day. She is the author of “The Wahls Protocol: How I Beat Progressive MS Using Paleo Principles and Functional Medicine”, “The Wahls Protocol: A Radical New Way to Treat All Chronic Autoimmune Conditions Using Paleo Principles”, and the cookbook “The Wahls Protocol Cooking for Life: The Revolutionary Modern Paleo Plan to Treat All Chronic Autoimmune Conditions”. She conducts clinical trials that test the effect of nutrition and lifestyle interventions to treat MS and other progressive health problems. She teaches the public and medical community about the healing power of the Paleo diet and therapeutic lifestyle changes that restore health and vitality. She hosts a Wahls Protocol Seminar every August where anyone can learn how to implement the Protocol with ease and success.

Key Takeaways:

– How did Dr. Wahls go from four years in a wheelchair to riding her bike to work? – What is the 3/3/3 nutrition program?

– Why are greens, colored vegetables and fruits, and sulfur-containing foods so critical?

– How is the mitochondria and myelin supported through diet?

– Why are mushrooms and seaweed key components of the protocol?

– What protein sources are utilized?

– What is the role if intestinal hyperpermeability in autoimmune diseases?

– Are lectins a problem for those with neurological disease?

– What is the role of the microbiome in supporting health?

– Do infections play a role in MS?

– Does environmental toxicity need to be considered to maximize health potential?

Connect With My Guest: Related Resources: Diet: Papers: Interview Date: December 11, 2018 Additional Information: To learn more, visit

Disclaimer: The content of this show is for informational purposes only and is not intended to diagnose, treat, or cure any illness or medical condition. Nothing in today’s discussion is meant to serve as medical advice or as information to facilitate self-treatment. As always, please discuss any potential health-related decisions with your own personal medical authority.


More on Wahls:






Irish Farmers Talk of Agony From Undiagnosed Lyme

Farmers talk of agony from undiagnosed Lyme disease


Farmers have opened up about the agony of suffering silently with Lyme disease, which is notoriously difficult to diagnose.

There are around 200 new cases of Lyme Disease every year, but the true incidence is not known, as it can often be overlooked, due to varied symptoms.

Pop star Avril Lavigne, actor Richard Gere, and former US president George W Bush are all said to have experienced the horrors of the Borrelia bacteria, which is carried by infected ticks.

‘Ear to the Ground’ presenter Ella McSweeney, left, with Charlie Harkin, who had Lyme disease, and his wife, Serena.

It can cause a range of debilitating symptoms, from fatigue and joint pain to neurological problems.

It is transmitted by tiny ticks that live outside on animals. Farmers are particularly vulnerable to the condition.

Jack Lambert, a consultant specialist in infectious disease at Dublin’s Mater Hospital, believes the disease is more common in Ireland than previously thought.

“We actually have to open up our mind up to this new disease, which is much more common than we were previously aware of,” said Dr Lambert.

“We need to resource, to educate the GPs on the frontline, who are seeing these patients, to even think about Lyme.

“We need to educate the specialists, who are seeing these patients with fibromyalgia and chronic fatigue and rheumatological conditions and neurological conditions, to even consider Lyme, because it’s not on their radar screen at present.

“Not every case of rheumatoid arthritis is going to be Lyme disease, but you should at least think about it and do the test and take a history.

In Thursday’s episode of RTÉ’s farming series Ear to the Ground, a farmer speaks of the devastation of suffering the symptoms, such as chronic fatigue and joint pain, and the failure to have his condition diagnosed.

Charlie Harkin, a part-time farmer from Inishowen, began to feel unwell on Christmas day four years ago.

He suffered with Lyme disease for two years before being diagnosed following a blood test.

“I was jumping for relief that someone was telling me what I had,” he said.

I wouldn’t wish this on my worst enemy. It is savage. It was one of the scariest things I ever went through in my life and I never want to do it again.

Dr Lambert said the disease is very treatable.

“My belief, and my observation from treating patients, is that even if it has been in your system for five or ten years, if you do all the necessary treatment — antibiotics, immune supplements, anti-inflammatories, things to fix the immune system — it is curable,” he said.

“If you catch it early, within six months, I think, sometimes, even a three- to six-week course of antibiotics does it, or even two to three months of antibiotics does it.”

Farmers are urged to avoid tick-borne infections by wearing repellent and by checking for ticks at the end of the day, looking out for a bulls-eye rash, flu-like symptoms, and nerve pain.



I’ve previously posted articles on Dr. Lambert, a Scottish doctor who is currently working as an Infectious Diseases consultant in a public hospital in Dublin, Ireland. He has been treating Lyme Borreliosis patients for 20 years in the USA and during the last 5 years in Ireland. He has also successfully treated young women who fell ill after their HPV vaccination, which seems to have stimulated a latent Lyme infection.

For those articles:

Some telling quotes by Dr. Lambert:

We are in the very primitive stages of our understanding of Lyme and co-infections. This is what I sometimes would like to do. Lyme is a bacteria, a spirochete. It gets into your body and causes all sorts of damage. Immunological damage, inflammatory damage.

“But it’s the bacteria. Dummy.”

We should not be calling it Chronic Fatigue or MUS, when we know it is caused by a bacteria. And the bacteria is hard to grow. And the immune system starts to attack the bacteria and causes all this inflammation. The immune system eventually starts to wear down. But when you treat many of these patients with all of these ‘garbage bag’ diagnoses, they get better with the antibiotics.

Antibiotics work against bacteria, anti-virals work against viruses. So when I treat someone with antibiotics and they get better, my conclusion is that this is a bacterial effect (although disbelievers say antibiotics have ‘immunological effects’).

So, I say to the disbelievers ‘It’s the bacteria, dummy’ and find better diagnostic tests to identify these bacteria. Don’t tell patients it ‘post-infectious’ when you are unable to grow the bacteria before treatment, and then can’t grow it during or after treatment.

Treating this; however, takes finesse and a trained & experienced eye.  This is not a straight-forward illness like strep-throat.  For more on that, please see:

Essential concepts while treating Bb:

  • Treat all forms of Bb
  • Treat coinfections as this is typically a polymicrobial illness
  • Lyme/MSIDS is slow growing and persistent requiring longer treatment time
  • Dr. Burrascano recommends Cycling.  This means that after a person has been symptom-free for 2-4 months stop treatment.  If and when symptoms return, start treatment again.  In his experience, 3-4 of these cycles typically allow most patients to achieve wellness, with the worst herx on the 3rd cycle.
  • Lyme/MSIDS wreaks havoc on the entire body requiring supplementation where imbalances occur
  • Inflammation requires changes and substances to reduce it
  • Address pain
  • Address insomnia
  • Some patients require higher doses of drugs as research has shown their blood levels aren’t high enough.  Without high enough blood levels, they won’t be killing pathogens and run the risk of allowing the pathogens to mutate
  • Address psychological issues if present
As you can see, this is far from a “take this pill and call me in the morning.”


Your Liver is Your Detox Organ. Here’s Why & How to Support it

Your Liver Is Your Detox Organ. Here’s Why & How To Support It

Image by Marc Tran / Stocksy

We humans are alive because of brilliant biochemistry, and while each system of our body has its own unique function, they are all inextricably linked and work together to keep us alive and thriving. When one system goes awry, it often affects other seemingly unrelated aspects of our health. This is especially true when it comes to detox, which is one of the biggest factors of poor health that I see in my patients.

With research starting to show the link between our increased toxin exposure and autoimmune conditions, it’s more important than ever for your body’s detoxification systems to be working properly. As your body’s largest organ, your liver is also the main detoxifier.

Why your liver is your detox organ.

Working in constant communication with your stomach, pancreas, gallbladder, and the rest of your digestive system, your liver is responsible for storing and converting nutrients from the foods we eat for our bodies to utilize. Through its role in the metabolism of fat, protein, and carbohydrates, your liver works to ensure that blood glucose levels are stabilized to prevent blood sugar imbalances and other metabolic problems. It works to filter out toxins from the foods you eat and environmental exposures as well as acting as a blood purifier, clearing out your blood of these impurities and only utilizing the necessary nutrients. Needless to say, if your liver isn’t working well, your ability to detox is going to be greatly affected.

When your liver is overloaded with toxins, it creates a cascade of systemic chronic inflammation, which further affects your liver’s ability to rid itself of these toxins. It becomes a vicious cycle between toxin buildup and inflammation that can only be broken through limiting your toxin exposure and supporting your liver’s natural ability to detox.

Detox rituals that support your liver.

I’ve written in the past about various ways to make your life a cleanse. But to really boost your detox pathways and liver function, these targeted natural tools are my go-to for next-level liver and detox support:

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1. Dandelion tea

Methylation is your body’s biochemical superhighway that controls your body’s ability to detox. B vitamins act as fuel for methylation and are found abundantly in dandelions. Brew up a cup of dandelion tea to support methylation and help support optimal liver function.

2. Milk thistle

This plant is one of the most well-researched natural remedies for treating liver problems and has been used for years to treat a number of different liver conditions, including hepatitis and alcoholic liver disease. Milk thistle aids in eliminating toxins that have built up in the liver in addition to helping restore liver cells that have been damaged from increased toxin exposure. You can take it in a supplement capsule or as a tea.

Image by Yoyochow23 / iStock

3. Garlic

Garlic helps to activate liver detox enzymes that work to break down the toxins that enter your body in order to effectively eliminate them. Thankfully, garlic makes a delicious addition to almost any recipe, so don’t be afraid to load up while cooking your next meal!

4. Sulfuric vegetables

Vegetables such as broccoli, broccoli sprouts, mushrooms, Brussels sprouts, and cauliflower are considered sulfuric and contain the powerful antioxidant glutathione. This antioxidant is essential for activating phase 1 and phase 2 liver detoxification.

5. Beets

Beets are great for helping break down toxins through increasing enzyme activity so that your body can eliminate them quicker. I love roasting them as a side or adding them to a salad seasoned with garlic!

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6. Red clover

This is one of my favorites for its ability to rid toxins from not only your liver but your spleen and lymphatic system as well. You can take it in capsule form or as an herbal tincture.

7. Burdock root

As a tea or supplement, this root does wonders for removing toxins, specifically heavy metals. With its natural diuretic properties, it works to flush out toxins by increasing fluid excretion as well as boosting your lymphatic system.

You don’t have to adopt all these rituals to support your liver, but by making yourself a cup of dandelion tea, adding garlic and beets to your next meal, or taking a red clover supplement, you can support your detox pathways going into 2019.


More on Detoxification:

Briefly, MSM stands for Methylsulfonylmethane and is 34% sulfur by weight. Sulfur plays a crucial role in detoxification and is an important antioxidant for producing glutathione. If you aren’t getting enough sulfur, glutathione can not work. Even if you have a diet rich in sulfur (think cabbage, onions, garlic, broccoli, etc – essentially the stinky veggies – and many other food items as well) your body still could use supplementation.




Lyme Mexico & Plasmapheresis

TOUCHED BY LYME: A look at Lyme Mexico and plasmapheresis

By Dorothy Kupcha Leland

I first heard about Lyme Mexico, Dr. Omar Morales, and plasmapheresis from a friend—a father whose 22-year-old son had been gravely infected with Lyme disease, Babesia, Bartonella and related conditions.

Despite oral, IV and other treatments from top Lyme doctors in the US, the young man’s health worsened by the day.

“My son was overrun with Babesia and Bartonella infections in his blood stream,” the father told me later. “About 90% of his red cells were infected. This level of infection was giving him life-threatening psychiatric and physical symptoms.”

The experts they consulted recommended a procedure called plasmapheresis.

What is plasmapheresis?

The process filters the blood, removes harmful substances such as overactive cytokines, pro-inflammatory mediators, heavy metals and toxins, and then returns it to the body.

Plasmapheresis is used throughout the United States for a variety of conditions, including Guillain-Barre syndrome and sickle cell disease, but not typically for tick-borne diseases (TBDs).

But, although many US hospitals have the capability of performing this procedure, this family couldn’t find one willing to do it for their son. (I assume this was due to the weird and destructive medical politics that surround Lyme and TBDs in this country. But I digress….)

Who is Dr. Omar Morales?

Finally, they learned about Dr. Morales and his clinic in Puerta Vallarta, Mexico, and took the young man there. He received plasmapheresis and a therapy called red blood exchange over a period of 11 days. According to the father, “By the third treatment, my son was coming back.”

By the final day of treatment, my friend says the young man was better than he had been in years and at that point, really started on his road back to health. The father credits Dr. Morales with saving his son’s life.

Knowing this background, I was eager to hear Dr. Morales’ presentation at the recent ILADS conference in Chicago—and pleased to have some time to chat with him afterwards.

Omar Morales attended college in the United States and medical school at the University of Guadalajara. He also received a second degree in transfusion medicine, which is concerned with blood transfusion and other blood-related issues. He then began working with his father, Dr. Raul Morales, a hematologist and transfusion medicine specialist, in Puerto Vallarta.

The two doctors Morales soon found that more and more of the people who came to them for help were infected with TBDs and related problems.

That led the younger Dr. Morales to start attending ILADS conferences, consulting with diverse TBD specialists and exploring new ways of treating these conditions. This process in turn led him to open the Lyme Mexico clinic.

Four steps to healing from TBDs

In order to restore a patient to health, Morales says it’s important to address TBDs in the following areas:

  • Treat the active infection
  • Eradicate biofilms and persisting cells
  • Eliminate toxins
  • Stimulate (re-educate) the immune system

Depending on the person’s individual needs, Lyme Mexico offers a variety of therapies to accomplish those objectives. These include various forms of apheresis (cleansing the blood and returning to the body), assorted IV treatments (including IVIG), extreme whole-body hyperthermia (which heats the body to create an artificial fever), ozone, and UV light blood irradiation.

Dendritic cell vaccines

Dr. Morales’ presentation this year at ILADS explained dendritic cell vaccines, which are made from the patient’s own cells taken from the blood. When this vaccine is given to the patient, it boosts the immune system by activating white blood cells to kill the selected bacteria.

According to Dr. Morales, dendritic cell therapy re-educates and modulates the immune system. This allows the patient’s own body to eliminate the infection while also re-educating other cells such as B cells (a type of white blood cell) to create more IgG immunoglobulins (an antibody that binds to many kinds of pathogens).

In addition to Lyme disease, his clinic treats other tick-borne infections, parasites, viruses, PANS/PANDAS, and other conditions.

Lyme disease and TBDs in Mexico

Many of the patients who come there are from the US and Canada, though TBDs are problematic in Mexico as well.

According to Dr. Morales, rickettsial diseases (such as Rocky Mountain spotted fever and ehrlichiosis) are the #1 TBD in Mexico. He says different forms of rickettsia have infected as many as 10 million Mexicans so far, versus the almost two million confirmed cases of Borrelia burgdorferi (Lyme).

Unfortunately, Morales says, most Mexican healthcare providers follow the belief that Lyme disease is a simple, self-limiting problem or an easy-to-treat issue.

However, he says that doctors in Mexico are not forced to follow a specific, conventional course of action with unresponsive cases. Thus, he says,

“In Mexico, there is some room for experimentation and freedom for physicians to be creative without being harassed.

Dr. Morales continues to actively pursue research aimed at finding new and more effective treatments for Lyme and other TBDs. He firmly believes that a multidisciplinary and integrative approach is essential.

The father who originally told me about Dr. Morales and Lyme Mexico had another comment to offer.

“Transfusions have risks and are expensive. But in my son’s case, NOT having it done would have killed him. We decided to take the risk and it saved his life.”

Click here for more information about Lyme Mexico.  

Click here for more information about Lyme disease and co-infections.

TOUCHED BY LYME is written by Dorothy Kupcha Leland,’s Director of Communications. She is co-author of When Your Child Has Lyme Disease: A Parent’s Survival Guide. Contact her at


**Comment**  Numerous stories are told within this link as well as the effectiveness of plasmapherisis for certain conditions.  Considering the connection between PANS/PANDAS, Lyme/MSIDS, and other autoimmune conditions, it would behoove doctors to learn about and utilize this treatment.





PANS/PANDAS A Survivor’s Story

 Approx. 12.5 Min


PANS/PANDAS is still misunderstood and undiagnosed.  Many doctors are completely clueless.  According to one Wisconsin doctor, 80% of his PANS/PANDAS patients also have Lyme/MSIDS.  Often an infected tick bite can trigger it.  It’s a perfect storm of events that can hijack your child.  Please learn all you can and share the information prolifically.  Children are losing their childhoods to this monster.

For more: