Archive for the ‘research’ Category

How Safe Are Topical NSAIDs Like Voltaren Gel?

https://www.peoplespharmacy.com/articles/how-safe-are-topical-nsaids-like-voltaren-gel

How Safe Are Topical NSAIDs Like Voltaren Gel?

FDA’s warning on doctor-prescribed topical NSAIDs like Voltaren Gel is scary. Are gels as dangerous as oral NSAIDs like ibuprofen or naproxen?

Oral NSAIDS Come With Other Worrisome Side effects:

Americans are in a lot of pain! Medscape provides physicians and other healthcare professionals up-to-date medical news and information. It offered this overview of “Nonsteroidal Anti-inflammatory drug (NSAID) Toxicity” on Sept. 15, 2023:

“More than 70 million prescriptions for NSAIDs are written each year in the United States. With over-the-counter use included, more than 30 billion doses of NSAIDs are consumed annually in the United States alone.”

(See link for article)

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**Comment**

Important article for Lyme/MSIDS patients who deal with excruciating pain.

Many oral NSAIDs can cause heart attacks and strokes, hypertension, irregular heart beats, dizziness, blood clots, fluid retention, heart failure, tinnitus, and liver or kidney damage.

Regarding topical NSAIDs, a Cochrane review for ACUTE pain showed that they provide similar relief as orals with minimal adverse events. So topical NSAIDs used for a short period of time appear to work and are fairly safe; however, less than a year later some of the same authors published a new review for CHRONIC pain which found they only worked for 10% more people than those who got a placebo for osteoarthritis and that there is no evidence for other conditions. While the authors admit the quality of evidence was low, the side-effects were wide ranging but supposedly mild and included:

  • headache
  • diarrhoea
  • drowsiness
  • dyspepsia [heartburn]

Some patients wrote in that they experienced more serious side-effects like stomach pain, abdominal cramps, and high blood pressure.

The article author is puzzled as to why the FDA took so long to allow topical NSAIDs to be sold over the counter when orals have been available OTC despite scary warnings.

For more:

 

Immunosuppression Has Doubled & Immune Compromised Mice More Susceptible to Bartonella

Increased Immunosuppression in US Adults

JAMA Network (Martinson, M.L. and Lapham, J.) 02.15.2024, published “Prevalence of Immunosuppression Among US Adults.” In this study, researchers found that immunosuppression in adults has increased in the past 8 years (2013-2021) through self-assessment reporting. The previous national estimate from 2013 was 2.7%, while the 2021 national estimate increased to 6.6%. Authors suggest that COVID 19 may have played a role in this increase.

The patterns in the distribution were similar in 2013 and 2012 for immunosuppression by sex, race, and age. Immunosuppression prevalence for women (7.9%) was higher than for men (5.2%). The highest rates of immunosuppression were found for American Indian or Alaska Native respondents (8.4%); White respondents (7.4%); and aged 60 to 69 years respondents (9.5%).

Authors note, as this population is at increased risk from viral and bacterial infections, increase of prevalence is an important consideration for public health in the US that would benefit from further study.


For More Information: 

Read JAMA Network Article

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0297280

A comparison of Bartonella henselae infection in immunocompetent and immunocompromised mice

Rebekah L. Bullard, Mercedes Cheslock, Shiva Kumar Goud Gadila, Ricardo G. Maggi, Edward B. Breitschwerdt, Ahmad A. Saied, Monica E. Embers

Published: February 12, 2024

https://doi.org/10.1371/journal.pone.0297280

Abstract

Bartonellosis refers to disease caused by the Bartonella genus of bacteria. The breadth of disease manifestations associated with Bartonella is currently expanding and includes regional lymphadenopathy, rheumatic, ocular, and neurological disorders. The dearth of knowledge regarding diagnosis, treatment and pathogenesis of this disease can be partially attributed to the lack of a reliable small animal model for the disease. For this study, Bartonella henselae, the most common species associated with human disease, was injected into Swiss Webster (SW) mice. When the outcome indicated that productive infection did not occur, SCID/Beige (immune compromised) mice were inoculated. While SW mice may potentially harbor an acute infection, less than 10 days in length, the SCID/Beige model provided a sustained infection lasting up to 30-days. These data indicate that SCID/Beige mice can provide a model to study Bartonella infection, therapeutics, and vector dynamics in the future.

For more:

Transforming Health & Sanitation: The Breakthrough of Chlorine Dioxide Solution

https://worldcouncilforhealth.substack.com/p/chlorine-dioxide

Chlorine Dioxide & Electro-Molecular Medicine: A New & Hopeful Paradigm

Dr Tess Lawrie caught up with Dr Andreas Kalcker, a biophysicist who has spent the past 17 years researching chlorine dioxide, to set the record straight.

Innovative medicine

Our cells are based on electricity, or electrons moving within the cell that are able to create 100,000 chemical reactions per second in each cell!”

Conventional medicine is fixated on treating symptoms with pharmaceuticals (i.e. chemicals). As a Biophysicist, Dr. Kalcker recognises the limitations of this biochemical view of physiology and medicine, which ignores the electrical nature of energy production in our cells. More fundamental than molecules are sub-atomic particles – protons and electrons – and it is this perspective that makes what Dr Kalcker calls ‘electro-molecular medicine’, not just an ‘alternative’ to allopathic medicine but a truly novel and innovative approach.

Chlorine confusion

Chlorine dioxide has been used to purify water for over 100 years, but it is now also used internally.  Many people are wary of chlorine dioxide, confusing it with bleach or chorine. Dissolved in water, it forms Chlorine Dioxide Solution (CDS), a yellow gas in liquid that breaks down to oxygen and harmless chloride ions (as in table salt).

On the other hand, bleach is a transparent solution of sodium hypochlorite, which should definitely not be taken internally. Chlorine dioxide is also not molecular chlorine, which consists of two chlorine atoms and exists as a corrosive gas.

.Chlorine dioxide is a completely different molecule from either bleach or chlorine.

Why it works

Chlorine dioxide is known as an oxidant, and oxidants have a bad reputation, as they can damage cells through the production of free radicals and reactive oxygen species (ROS). But Dr Kalcker points out that viewing oxidation as something negative is irrational; it is a natural and necessary process of life that needs to be better understood and optimised.

Oxidants can be toxic or helpful in the body – it depends on voltage differences. Fluorine, for example, is a toxic oxidant due to its very high voltage (2,870 mV) and hydroxyl groups (OH-) that harm the cells. Our cells work best at voltages between 1,000 and 1,500 mV, and oxygen – an oxidant essential to life – falls within this range. At the lower end of the range, chlorine dioxide, with a voltage of 940 mV, does not produce hydroxyl groups and is safe for human cells; however, it destroys bacteria, fungi, and heavy metals, which have lower voltages and are therefore oxidised.

What’s interesting is that chlorine dioxide can work both as both an oxidant (neutralising pathogens) and an antioxidant (reducing damaging hydroxyl groups). It therefore plays the role of a modulator, restoring electrical charges within a voltage range that is perfect for the human cell.

Illness as a lack of energy

Dr Kalcker has come to view illness as a lack of energy related to poor mitochondrial function and metabolic acidosis. He sees chlorine dioxide as helping to address this by providing the cells with oxygen. While oxygen is normally transported to the tissues in red blood cells, chlorine dioxide is so tiny (three atoms only) that it can diffuse anywhere in the body. In effect, the chloride ion is the carrier that takes oxygen to tissues with an acidic pH and releases millions of oxygen molecules, supporting the cells to produce energy, and therefore to heal.

CDS and Covid-19

Despite mainstream media denials, large clinical trials during the Covid-19 period showed that CDS was highly efficacious in treating and preventing Covid-19 disease. A study of over 1,000 patients showed 99.3% efficacy, with recovery within only four days compared with nearly a month with standard treatments. While six percent of patients experienced minor side effects (dry mouth, headaches), there were no adverse effects. Another clinical trial of 1,000 people living with patients infected with coronavirus was over 98% effective prophylactically. One of the most exciting findings was that a number of people treated with CDS found that other serious conditions resolved, including high blood pressure, diabetes, and even end-stage cancers. Dr Kalcker feels that CDS and its mechanisms of action represent the biggest discovery in medicine over the past hundred years.  

How do you make CDS?

CDS is a concentrated 0.3% aqueous solution of chlorine dioxide with a neutral pH, lacking sodium chlorite (NaClO2). For step-by-step instructions on how to produce it yourself, see the video of Dr Kalcker’s protocol.

Remain sceptical … and open to learning

When we’re stuck in a well-established paradigm, it’s really hard to embrace radical change. Being sceptical of unfamiliar ideas is normal! But just as a shipbuilder working on one of Columbus’s caravels would never have imagined flying from the Old World to the New World in a winged metal tube, so we need to be willing to unlearn much of what we know in order to create a Better Way for medicine. Electro-molecular medicine offers many insights to help us forge a path beyond Big Pharma-captured medicine, which has clearly lost its way.

While there are still many aspects that need to be explored further when it comes to Chlorine Dioxide, the results seen thus far have indeed been promising.

Watch the full interview in the following link:

https://worldcouncilforhealth.org/multimedia/chlorine-dioxide-solution/  Video Here (Approx. 53 Min)

Scroll to about the 14:00 mark to hear the interview.

Transforming Health and Sanitation: The Breakthrough of Chlorine Dioxide Solution

You can also find this video on: Bitchute | Rumble | Facebook | Gettr | Twitter

Join us as Dr Tess Lawrie sits down with Dr Andreas Kalcker, a pioneer in alternative health solutions. Together, they explore the potential and controversies surrounding Chlorine Dioxide. Dr Kalcker shares his insights on Chlorine Dioxide, a compound that’s been the center of heated debates in the realms of health and sanitation.

With Dr Lawrie’s critical eye and Dr Kalcker’s extensive research, this interview promises to shed light on the science, the myths, and the real-world applications of this controversial solution.

About Dr Andreas Kalcker

  • Andreas Kalcker is a biophysicist of German origin who has lived a large part of his life in Spain and has been residing in Switzerland for several years.
  • He has researched and registered several international patents related to the therapeutic use of chlorine dioxide for hypoxia, inflammation, infection, sepsis, and SARS-CoV-2.
  • Dr Kalcker’s thesis and experience were extensively discussed in his first book, CDS – Health is Possible. Years later, the publication of his second book, Forbidden Health, demonstrates how the recovery of diseases from A to Z, once considered incurable, achieves remarkable success but sparks a wide controversy in the world of conventional science and the “establishment”.
  • Currently, Dr Kalcker, through the International ALK Foundation, continues the comprehensive research of the ClO2 molecule in the form of CDS. He is also developing multidisciplinary projects in vital areas for human well-being, such as water treatment, agriculture, veterinary medicine, sanitary hygiene, and potential therapeutics from an electromolecular approach.
  • Learn more at andreaskalcker.com.

(See link for article and video)

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For more:

A Significant Step Forward in Lyme Disease Research (Don’t Hold Your Breath)

https://giving.massgeneral.org/stories/a-significant-step-forward-in-lyme-disease-research

A Significant Step Forward in Lyme Disease Research

The newly funded multidisciplinary Lyme disease program will improve patient care and seek new breakthroughs in early detection, treatment and prevention.

By Nancy Kilburn

11/27/23

Excerpts:

To address this public health challenge, Mass General is establishing a Multidisciplinary Lyme Disease Clinical Research Program. Made possible with the support of Phillip H. Morse, Vice Chairman of the Boston Red Sox, the program will bring together experts from infectious diseases, neurology, rheumatology and other departments across the hospital to provide more coordinated care for patients and advance research toward new treatments and methods for early detection and prevention.

In all, the Morse family’s transformational gift provides funding for an endowed chair — recently awarded to Dr. Steere — and the creation of a multidisciplinary clinic with a Lyme disease research program.

The Morse Endowed Chair in Medicine, the highest academic honor Mass General can give, provides Dr. Steere with flexible funding to pursue high-impact work. As Chair, Dr. Steere is launching the Lyme disease clinical research program, alongside Jacob Lemieux, MD, PhD, a leading physician-scientist who studies the genetics of Lyme and other tick-borne illnesses. “Jake represents the next generation of Lyme research and this gift will help us realize the vision of what they can accomplish in the future,” says Dr. Steere.  (See link for article)

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SUMMARY:

  • One of the goals is that patients will receive “coordinated” care in one location.
  • The article erroneously states that a “small subset” of patients go on to suffer with persistent symptoms. (This myth must be destroyed or patients will never get the attention they deserve)
  • The article states patients are frustrated by the slow rate of progress in treating long-Lyme. (Ya think?!)
  • Regarding the NIH, research into persistent symptoms as been a “hard sell.” (This is the understatement of the year!)
  • Due to this FACT, research into persistent symptoms would not be possible without philanthropic support. (They fully admit that doing ANY research with government grants is a WASTE OF TIME.  Please remember this when you read about Lyme advocates clamoring for more government money/research. It is never yielded anything productive for patients and it never will unless the accepted narrative is replaced by reality)

It remains to be seen if this new interdisciplinary group is any different from the same-o-same-o of the past.  I’m not holding my breath.  The juggernaut of corrupt research institutions in academia as well as in ‘public health’ agencies is very real and only appears to be worsening.

For more:

I think we have our answer about this already. I’d love to be wrong.

Fraudulent Scientific Study Epidemic

For anyone in Lymeland, none of this should come as a shock. It is a perfect example of why Zooming with Congress for more Lyme funding is an absolute waste of time.  The Cabal has been designing flawed studies regarding Lyme/MSIDS for over 40 years by basing everything on known faulty 2-tiered testing and ‘classic’ symptoms which are not experienced by a majority of patients. Further, they simply ignore world-wide research showing pathogen resistance. COVID, once again, has pulled back the curtain to reveal the ugly world of bought-out science, science journals, government, and academia.

http://

Fraudulent Scientific Study Epidemic Destroying Credibility of Medical Research

The Hill

2/20/24

https://www.theguardian.com/science/2024/feb/03/the-situation-has-become-appalling-fake-scientific-papers-push-research-credibility-to-crisis-point

The situation has become appalling’: fake scientific papers push research credibility to crisis point

Last year, 10,000 sham papers had to be retracted by academic journals, but experts think this is just the tip of the iceberg

Tens of thousands of bogus research papers are being published in journals in an international scandal that is worsening every year, scientists have warned. Medical research is being compromised, drug development hindered and promising academic research jeopardised thanks to a global wave of sham science that is sweeping laboratories and universities.

Last year the annual number of papers retracted by research journals topped 10,000 for the first time. Most analysts believe the figure is only the tip of an iceberg of scientific fraud(See link for article)

“…..we lack a solid foundation of trustworthy findings. And it’s getting worse and worse.” ~ Professor Dorothy Bishop, Oxford University

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**Comment**

Bishop states that these sham papers are due to doctors and scientists seeking promotion and that shadow organizations known as “paper mills” fabricate work for publication in journals. Journal editors are bribed to accept articles and paper mills have embedded agents who publish false work.

She mainly blames China, but states it has spread to India, Russia, former Soviet Union states and eastern Europe.

The U.S. is hardly immune.

For more: