Archive for the ‘Lyme’ Category

Bella Hadid Explains ‘Truth’ About Symptoms of Her ‘Invisible’ Illness, Lyme Disease

https://people.com/health/bella-hadid-gets-candid-about-symptoms-of-her-invisible-illness-lyme-disease/?  Video Story Here

The model said she’s experienced various symptoms “since I was probably 14, but more aggressively when I turned 18”

By Benjamin VanHoose

August 26, 2020 0
NEW YORK, NY - OCTOBER 25: Model Bella Hadid attends Dior Beauty celebrates The Art of Color with Peter Philips on October 25, 2016 in New York City. (Photo by Nicholas Hunt/Getty Images for Dior Beauty)
Bella Hadid
NICHOLAS HUNT/GETTY

Bella Hadid is sharing the “truth” about her Lyme disease symptoms.

On Tuesday, the 23-year-old model opened up about battling Lyme disease daily, explaining to her followers on her Instagram Story what she typically experiences because of the “invisible” illness. Hadid re-posted diagrams and infographics about Lyme disease shared by chef Joudie Kalla’s Palestine on a Plate Instagram account.

Hadid, on one slide, drew arrows to point out nearly 30 common symptoms she faces, including headaches, brain fog, insomnia, and a sensitivity to light and noise. She also flagged anxiety, confusion, nausea, disordered eating, joint pain, and weight gain and loss as affecting her too.

“Every day I feel at least 10 of these attributes without fail … since I was probably 14, but more aggressively when I turned 18,” wrote Hadid.  (See link for article)

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**Comment**

The video lacks substance and impractically, but jokingly states, we shouldn’t go outside.  Please see the following for more practical advice on how to live while being exposed to ticks:  https://madisonarealymesupportgroup.com/2019/04/12/tick-prevention-2019/

Hopefully in the next few years we should have Nootkatone products available:  https://madisonarealymesupportgroup.com/2020/08/11/nootkatone-registered-by-epa-insect-repellent-products-could-be-available-by-2022/

The Need For An Alternative to Current Antibody-Based Lyme Disease Diagnostic Tests

https://globallymealliance.org/the-need-for-an-alternative-to-current-antibody-based-lyme-disease-diagnostic-tests/

by Timothy J. Sellati, Ph.D., Chief Scientific Officer, Global Lyme Alliance

An early and accurate test result is critical to effectively treat most diseases. Especially Lyme disease. The earlier one is diagnosed and treated, the better the odds are for recovery. Unfortunately, current Lyme disease diagnostics are highly inaccurate for early diagnosis, having a direct negative impact on patients’ health.

The most common means of laboratory diagnosis of Lyme disease is an indirect test that detects the immune response (antibodies) triggered by the presence of Borrelia burgdorferi, the causative agent of Lyme disease. The current standard two-tiered test (STTT) relies on a first-tier enzyme immunoassay (EIS), that is relatively sensitive but not extremely specific. If positive or equivocal the EIA is followed by a second-tier Western immunoblot assay, that shows improved specificity. Shortcomings associated with the STTT include missing as much as 60% of early Lyme cases due to no or low antibodies levels during the first few weeks of infection.  Moreover, the second-tier assay is technically difficult and time-consuming to perform and the results are prone to subjective interpretation resulting in both false negative and false positive results.  Beyond the tests’ limitations, detection of antibodies as a basis for diagnosis is confounded by the fact some patients may not produce antibodies against B. burgdorferi, while others will start and then stop producing them, and still others will continue to produce antibodies long after treatment and treatment/cure and resolution of symptoms.

As part of our mission to conquer Lyme disease, in 2017 Global Lyme Alliance was responsible for a report that publicly addressed the limitations of current two-tiered tests while simultaneously seeing the real potential of newer technologies to overcome many of the limitations. This finding supports GLA’s ongoing work with top researchers to develop a more accurate diagnostic test that will better serve patients and the community.

Also in 2017, GLA partnered with Ionica Sciences, a startup diagnostics company based at Cornell University’s McGovern Center life sciences incubator in Ithaca, New York, to accelerate the development of a highly sensitive direct Lyme disease diagnostic test. Called IonLymeTM, this novel testing strategy recognizes a specific bacterial protein [Outer surface protein A (OspA)] shed in minute quantities by B. burgdorferi into the bloodstream during early infection rather than waiting weeks for antibodies to be produced. OspA is thought to only be in the blood during active infection. So, IonLyme not only detects early Lyme disease much better than current solutions, it also allows testing for reinfection, and can help to determine if a person is cured of active Lyme disease.

While still in the validation phase of development Ionica Sciences has made a significant advance by demonstrating excellent diagnostic accuracy with IonLymeTM using biobanked blood samples. Currently, the assay generates statistically significant results with >90% clinical sensitivity and >95% clinical specificity. Thus, while other companies have made important strides in developing modified two-tiered tests (MTTTs), that rely on two EIAs rather than an EIA and Western immunoblot, which show increased sensitivity in diagnosing early Lyme disease, their approach is still limited by their focus on measuring antibody responses.

GLA is a strong believer that the more minds that work toward a goal, the better. Partnerships like we have with Ionica will speed the delivery of the tools and resources that will help patients, from diagnostics to treatment. If you are interested in supporting Ionica’s current endeavor and want to participate in their current fundraising campaign, click here.

Related posts:
Progress in New Ionica Sciences Lyme Disease Diagnostic Test Funded by Global Lyme Alliance
The Advantage of Public-Private Partnerships to Accelerate Progress for Patients
Global Lyme Alliance Partners with Ionica Sciences to Develop New Lyme Disease Diagnostic Test

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**Comment**

Testing has been problematic from the beginning, leaving thousands upon thousands undiagnosed or misdiagnosed.

Please notice a few things:  they state here that OspA is “thought” to only be in the blood stream during active infection.  So, this is an unknown that I’m sure mainstream medicine will point out.  Secondly, I’m not aware of what stage patients are included in the biobanked blood samples.

In other words, while this is a test for acute infection (early), what stage of patients’ blood are they using for validation?

And lastly, while we desperately need accurate tests so people can get diagnosed promptly and then receive prompt treatment, this will NOT include any coinfections present and of course completely leaves out the huge subset of patients that are chronically experiencing symptoms – which also needs testing to prove their condition so they too can receive appropriate treatment.

I remain hopefully skeptical.

Natural SIBO Solutions For Lyme Patients

https://rawlsmd.com/health-articles/natural-sibo-solutions-for-lyme-patients-how-to-overcome-this-painful-gut-problem?

Natural SIBO Solutions for Lyme Patients | RawlsMD

Natural SIBO Solutions for Lyme Patients: How to Overcome This Painful Gut Problem

by Jenny Lelwica Buttaccio
Posted 8/21/20

Does your belly feel bloated more often than not? Is abdominal pain disrupting your life to the point where you have to curb your activities, change up the foods you eat, or trade button-up pants for stretchy ones with a comfy, elastic waistband?

If you answered “yes” to these questions, you’re not alone. However, that doesn’t mean constant bloating and an irritated digestive tract are normal, even for those of us living with chronic Lyme disease or another chronic illness. Instead, these persistent gut symptoms are a sign you may be impacted by a distressing gut problem known as small intestinal bowel overgrowth (SIBO).

To manage and heal from this condition, it’s important to have a better understanding of the factors that foster SIBO, the inner working of your digestive tract, and how the balance of microbes in your body can be tipped from having mostly microorganisms that typically aid in digestion to favoring those that cause an onslaught of symptoms. Here’s what you need to know to restore a healthy gut and get your life back again.

SIBO, Defined

Your gut or gastrointestinal (GI) tract — which consists of the mouth, esophagus, stomach, pancreas, liver, gallbladder, small intestine, colon, and rectum — is home to trillions of microbes known as the microbiome, most of which are bacteria. Bacterial microflora can be beneficial to you because they aid in such functions as digesting food, enhancing immunity, and managing inflammation.

When good bacteria reside in the right locations of your GI tract, you’ll likely have a relatively easy digestive process that you may not even have to think twice about. But if you have an overgrowth of bacteria specifically in the small intestine, conditions are hospitable for the development of SIBO and subsequent disrupted digestion.

Intestinal bacteria, Gut flora

The small intestine is the place where your digestive juices break down the food you consume. From there, nutrients and minerals are absorbed through your gut walls into your bloodstream and delivered to your body’s tissues.

Typically, the small intestine contains very few bacteria because your stomach acid and the speed with which substances move through the small intestine make it an unwelcome environment for most microbes to survive. But there are some exceptions.

“People who have gut dysfunction like SIBO usually have poor gut motility,” says Dr. Bill Rawls, Medical Director of RawlsMD and Vital Plan. “That means that food is slow to make its way through the digestive tract, so it sits in the small intestine where it ferments, produces gas, and irritates the gut.” In short, the inability of food to move swiftly through the GI tract, combined with low concentrations of stomach acids, creates a hotbed for myriad bacteria to flourish.

Unfortunately, in a world filled with gut disruptors like high-carbohydrate foods and acid-reducing stomach medications like Tums or Pepcid, SIBO may be more common than many people realize. However, all roads lead back to the health of your immune system: “If your immune system is disrupted, you’re going to have less ability to keep the microbes in the small intestine or elsewhere in the gut in check,” says Dr. Rawls.

Let’s take a look at some of the symptoms, causes, and natural solutions to improve and alleviate SIBO and support your immune system.

Symptoms of SIBO

The symptoms of SIBO tend to be similar to those experienced with irritable bowel syndrome (IBS). In fact, bacterial overgrowth in the small intestine may be the cause of IBS in some individuals. However, not everyone who has IBS has SIBO and vice versa, suggests a review in the journal Gut and Liver. Estimates vary widely, with anywhere between 4% and 78% of people with IBS also having SIBO.

woman curled up in bed, holding stomach, stomach pain

The biggest symptoms that are attributed to SIBO are gas, bloating, and abdominal pain. The reason? “When bacteria in the small intestine ferments, there’s really nowhere for that air or gas to go, so it becomes trapped, causing intense pressure in your belly,” says Dr. Rawls. “It takes a long time for that gas to get out. Meanwhile, it causes cramping and discomfort.”

The list of top symptoms that might occur as a result of SIBO include:

  • Gas
  • Bloating
  • Abdominal pain
  • Diarrhea
  • Constipation
  • Feeling full
  • Decreased appetite
  • Nausea
  • Fatigue

In more severe cases, SIBO could result in involuntarily weight loss, anemia, or malnutrition.

Causes of SIBO

The three main contributors to SIBO are gastrointestinal dysfunction, low stomach acid production, and poor gut motility, says Dr. Rawls.

“Gastric dysfunction starts in the stomach, and if you don’t have good acid production, you’ll have poor digestion and an ample supply of undigested food to fuel the bacteria in your small intestine,” says Dr. Rawls. Structural issues, like those caused by intestinal scar tissue or diverticulosis (when small, bulging pouches form in the lining of the digestive tract), certainly contribute to gut dysfunction, as do autoimmune diseases such as Crohn’s disease, celiac, and multiple sclerosis.

Slow motility — originating from factors like vitamin deficiencies, medication side effects, and inflammation — along with eating high-carbohydrate and processed foods are chief offenders as well, says Dr. Rawls. Essentially, motility problems hinder digestion, while processed foods feed the bacterial overgrowth.

woman analyzing pills and instructions while laying in bed

Also, if you’ve taken antibiotics for Lyme disease, you may be wondering how likely they are to cause SIBO. Yes, antibiotics disrupt your microbiome’s flora, says Dr. Rawls, but it’s not the only driving agent. Other things that perpetuate gut dysfunction include chronic stress, poor sleep, immune dysfunction, as well as the compromised gut flora and highly-processed dietary considerations already mentioned. In short, it’s often difficult to pinpoint an exact cause for SIBO because there are a multitude of factors that affect gut health.

How to Test for SIBO

An evaluation for SIBO may involve breath or fluid testing. However, testing runs the risk of not being very reliable.

“I’ve found evaluating the symptoms to be most useful,” says Dr. Rawls. “If your belly is taut like a drum, and you have all kinds of cramping, you probably have SIBO.” However, if you’re not able to get a proper diagnosis, or if treatment isn’t producing positive outcomes, testing might be a logical step.

Typical SIBO tests include:

  • Breath test: This test is non-invasive and measures the amount of gas — such as hydrogen or methane — that you exhale after consuming a sugar-water solution. An increase in hydrogen or methane could be indicative of SIBO, though the test lacks some specificity for bacterial overgrowth.
  • Small intestinal aspirate: A sample of fluid is obtained from your small intestine by inserting a tube down your throat and maneuvering it through the upper portion of your digestive tract. Then, the fluid sample is cultured in a lab to watch for the growth of bacteria. There’s a chance this test could yield false positive results in some people, but it is indicated as the gold standard for SIBO testing. However, because of the invasive and expensive nature of it, the breath test is quickly becoming a popular alternative.
Natural Ways to Improve SIBO

There are a variety of natural tools to manage SIBO while also — and most importantly — working to address the underlying causes. It’s crucial to do these two things simultaneously, because the problem will likely come back if you choose an intervention that focuses solely on symptom management.

That’s why the primary conventional treatment for SIBO — antibiotics — really isn’t a great solution. Yes, antibiotics might help decrease the number of bacteria in your small intestine, but they don’t address the underlying reasons for bacteria being there in the first place. And once you stop taking the antibiotics, bacteria will make their way back to the small intestine and continue stirring up painful symptoms if you haven’t dealt with root causes.

While you can’t eradicate every threat to your digestive system, you can work to implement strategies that foster the health of your microbiome and immune system, curtail fuel sources to harmful bacteria, and decrease gut irritation. Luckily, with the right combination of diet, lifestyle modifications, and some herbal therapies, you can combat the discomfort associated with SIBO and restore your overall gut health.

1. Take Gut-Supporting Herbs and Foods.

“When trying to recover from SIBO, it’s important to enhance gut motility and digestion,” says Dr. Rawls. Notably, herbal therapy is well suited for this task, because plants have a variety of built-in antimicrobial, antioxidant, and detoxifyingqualities that support the health of your microbiome by shifting the balance in favor of beneficial microorganisms. Additionally, herbs help to normalize immune function, keeping gut microbes in check and managing unpleasant symptoms.

picture split in grid. berberine, dandelion, bitters, ashwagandha, apple cider vinegar

Dr. Rawls’ preferences for herbal therapy for the gut are as follows:

  • Berberine: As an excellent antimicrobial herb, berberine helps knock back pathogens throughout the small intestine and the digestive tract. Found in the stems, bark, roots, and rhizomes of a range of herbs, berberine helps to soothe irritated intestines and normalize bowel movements.
  • Bitters: Bitter herbs stimulate the production of saliva, enzymes, and bile we need for motility and gut function. Bitters that promote digestion include burdock, dandelion, fennel, and ginger. Fresh bitter herbs can make an excellent addition to salads and cooked dishes. However, the herbs are typically available in combination in many digestive support supplements as well.
  • Ashwagandha: This adaptogenic herb has antimicrobial, anti-inflammatory, and immunomodulating properties. Ashwagandha has been used as a medicinal herb in traditional Indian and African medicine for thousands of years. One of the reasons for its appeal is that it’s a multi-use herb that reinforces your resistance to stress, allowing you to cope with stressful circumstances and get a better night’s sleep — two areas of concern that are essential to address healing from SIBO.
  • Hydrochloric Acid (HCL): The less stomach acid you produce, the more trouble you’ll have digesting your food. A supplement containing HCL can be a cost-effective way to augment normal gastric activity and break down your food.
  • Apple Cider Vinegar (ACV): Taken at mealtime, ACV increases the stomach’s acidity for better digestion. ACV contains acetic acid, an antimicrobial agent that may be effective at quelling pathogenic microbes in the gut and reducing inflammation. However, the taste of ACV can be a bit shocking. To make it more palatable, Dr. Rawls recommends consuming 2 tablespoons of ACV in 6 ounces of water with a drizzle of honey.
2. Cook Your Food.

When SIBO (or chronic Lyme!) symptoms flare and you’re uncomfortable or in pain, toiling away in the kitchen over a hot stove might seem like the last activity on your mind. But eating cooked food gives your body a head start on digesting meals, allowing your gut more time to heal and repair.

To make cooking a less stressful part of your day, be sure to stock up on healthy staples (think: quality proteins, vegetables and greens, and healthy fats), have a go-to meal handy for your most challenging days, and prepare in bulk whenever possible. All it takes is a few simple tricks to make cooking a more pleasant experience for you.

3. Reduce Your Eating Window.

Digesting food places significant energy demands on your body. If your eating schedule is such that you’re grazing or snacking throughout the day, you’re not giving your irritated digestive tract a break and might be aggravating SIBO.

antique clock on white plate, beside for and knife

“Reducing your eating window and trying to eat less often prevents your small intestine from being inundated with more bacteria, and it allows time for it to empty, take a break, and starve the bacteria of the nutrients they need to flourish,” says Dr. Rawls.

To give your gut ample time to rest, Dr. Rawls recommends a 12- to 16-hour window without consuming food, a method similar to intermittent fasting or mini-fasting. For example, eating all of your meals between 10 am and 6 pm would allow you to have a window of 16 hours where your body can work on digesting the contents of the day and empty the small intestine. A schedule of 7 am to 7 pm would give your body 12 hours to complete the act.

However, a rigid schedule isn’t going to work for everyone, and if you’re really ill, you may not tolerate altering your eating times until you’re further along in your healing. “If you can keep your window at 12 to 16 hours, that would be great. But you have to find what works best for you,” suggest Dr. Rawls. “You have to enjoy life.”

4. Make Time for Sleep.

Sleep is a vital step to improving gut motility, normalizing immune function, and recovering from SIBO. The digestive process takes 6 to 8 hours to move food from the stomach through your small intestine. Therefore, the later you eat, the more your body will divert resources to the process of digestion late into the night, and all that activity can keep you awake.

But it’s also a catch-22: “If you have bad sleep, your body won’t be able to do what it needs to do, including facilitating the digestive process,” says Dr. Rawls.

woman asleep in bed, dark room

So how do you improve your sleep? In addition to reducing your eating window, the following sleep hacks can help:

  • Stick to a sleep schedule, so your body learns the rhythms of day and night.
  • Avoid using electronic devices after 9 pm to cut down on your exposure to stimulating blue light that can interrupt your ability to produce melatonin.
  • Tone down your nervous system and prepare for sleep by doing a calming activity such as gentle yoga, a warm bath, or breathing exercises.
  • Maintain a cool temperature in your bedroom — 67° to 72° is usually conducive to sleep for most people.
  • Wear a sleep mask to block out excess light that can keep you awake at night.

Though SIBO resides in the small intestine, it takes a whole-body approach to care for your gut. “Healing depends on getting things moving again, enhancing digestion, and restoring healthy immune function,” says Dr. Rawls. Support your gut and overall health with soothing herbs, cooking your food, reducing your eating window, and getting enough sleep to jumpstart your recovery.

Dr. Rawls is a physician who overcame Lyme disease through natural herbal therapy. You can learn more about Lyme disease in Dr. Rawls’ new best selling book, Unlocking Lyme.
You can also learn about Dr. Rawls’ personal journey in overcoming Lyme disease and fibromyalgia in his popular blog post, My Chronic Lyme Journey.

REFERENCES
1. Dukowicz AC, Lacy BE, Levine GM. Small intestinal bacterial overgrowth: a comprehensive review. Gastroenterol Hepatol (N Y). 2007;3(2):112-122.
2. Ghoshal UC, Shukla R, Ghoshal U. Small Intestinal Bacterial Overgrowth and Irritable Bowel Syndrome: A Bridge between Functional Organic Dichotomy. Gut Liver. 2017;11(2):196-208. doi: 10.5009/gnl16126
3. Rubio-Tapia A, Barton SH, Rosenblatt JE, Murray JA. Prevalence of small intestine bacterial overgrowth diagnosed by quantitative culture of intestinal aspirate in celiac disease. J Clin Gastroenterol. 2009;43(2):157-161. doi: 10.1097/MCG.0b013e3181557e67
4. Small intestine aspirate and culture. MedlinePlus website. https://medlineplus.gov/ency/article/003731.htm#:~:text=A%20sample%20of%20fluid%20from,of%20bacteria%20or%20other%20organisms.

 

62% Adult Taiga Ticks Found With Borrelia spp. in Finland

https://pubmed.ncbi.nlm.nih.gov/32727555/

. 2020 Jul 29;13(1):384.

doi: 10.1186/s13071-020-04259-z.

Questing abundance of adult taiga ticks Ixodes persulcatus and their Borrelia prevalence at the north-western part of their distribution

Abstract

Background: Because ixodid ticks are vectors of zoonotic pathogens, including Borrelia, information of their abundance, seasonal variation in questing behaviour and pathogen prevalence is important for human health. As ticks are invading new areas northwards, information from these new areas are needed. Taiga tick (Ixodes persulcatus) populations have been recently found at Bothnian Bay, Finland. We assessed seasonal variation in questing abundance of ticks and their pathogen prevalence in coastal deciduous forests near the city of Oulu (latitudes 64-65°) in 2019.

Methods: We sampled ticks from May until September by cloth dragging 100 meters once a month at eight study sites. We calculated a density index (individuals/100 m2) to assess seasonal variation. Samples were screened for Borrelia burgdorferi (sensu lato) (including B. afzelii, B. garinii, B. burgdorferi (sensu stricto) and B. valaisana), Borrelia miyamotoi, Anaplasma phagocytophilum, Rickettsia spp., Neoehrlichia mikurensis, Francisella tularensis and Bartonella spp., Babesia spp. and for the tick-borne encephalitis virus.

Results: All except one nymph were identified as I. persulcatus. The number of questing adults showed a strong peak in May (median: 6.5 adults/100 m2), which is among the highest values reported in northern Europe, and potentially indicates a large population size. After May, the number of questing adults declined steadily with few adults still sampled in August. Nymphs were present from May until September.

  • We found a striking prevalence of Borrelia spp. in adults (62%) and nymphs (40%)
  • B. garinii (51%) and B. afzelii (63%) being the most common species
  • 26% of infected adults were coinfected with at least two Borrelia genospecies, mainly B. garinii and B. afzelii, which are associated with different host species

Conclusions: The coastal forest environments at Bothnian Bay seem to provide favourable environments for I. persulcatus and the spread of Borrelia. High tick abundance, a low diversity of the host community and similar host use among larvae and nymphs likely explain the high Borrelia prevalence and coinfection rate. Research on the infestation of the hosts that quantifies the temporal dynamics of immature life stages would reveal important aspects of pathogen circulation in these tick populations.

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**Comment**

Yes, humans are hosts for Taiga ticks.

There is a misnomer in this article:  “As ticks are invading new areas northwards....”  This false narrative tries to make tick movement and disease proliferation a climate issue, when it’s not.

This makes it sound as if ticks are ONLY invading new areas to the North.  They are also invading new areas in the South (and everywhere else for that matter) and all of this despite the weather.  

For More:  https://madisonarealymesupportgroup.com/2019/06/17/ontario-public-health-officials-called-out-on-shoddy-biased-research-utilizing-an-erroneous-climate-change-model-to-program-a-futuristic-tick-problem/

https://madisonarealymesupportgroup.com/2018/11/07/ticks-on-the-move-due-to-migrating-birds-and-photoperiod-not-climate-change/

Department of Health: Lyme Disease, COVID-19 Share Symptoms

https://www.dailyitem.com/news/local_news/department-of-health-lyme-disease-covid-19-share-symptoms/

Department of Health: Lyme disease, COVID-19 share symptoms

Department of Health: Lyme disease, COVID-19 share symptoms
Robert Inglis/The Daily Item Ronald Keister of Laurelton recently contracted Lyme disease from a tick bite.
Ronald Keister late last month started feeling muscle and joint aches and developed a low-grade fever, making him wonder if he somehow contracted COVID-19.
The Laurelton resident, worried that his wife who has health problems was in danger, called his doctor to ask if he should be tested for the novel coronavirus. He was told to wait two days to see if the fever would go up; in the meantime, he and his wife noticed a big red welt on his shoulder. Keister had Lyme disease.
“We have woods out back, and I’m out there all the time,” said Keister. “I’ve had ticks before, and had no problems. I never saw the tick on this one.”