https://www.sciencedirect.com/science/article/pii/S096758682500195X?

Expression of SARS-CoV-2 spike protein in cerebral Arteries: Implications for hemorrhagic stroke Post-mRNA vaccination

https://doi.org/10.1016/j.jocn.2025.111223Get rights and content
Under a Creative Commons license
Received 31 January 2025, Accepted 31 March 2025, Available online 3 April 2025, Version of Record 3 April 2025.
Open access

Highlights

  • Spike protein expression was detected in 43.8% of vaccinated patients.
  • SARS-CoV-2 spike protein persists in cerebral arteries up to 17 months post-vaccination.
  • Spike protein was expressed in the intima of the cerebral arteries.
  • In situ hybridization confirmed vaccine- and virus-derived spike protein mRNA.
  • Findings highlight concerns about mRNA vaccine biodistribution and long-term safety.

Abstract

Background

The rapid deployment of mRNA vaccines for SARS-CoV-2, such as BNT162b2 (BioNTech-Pfizer) and mRNA-1273 (Moderna), provided a critical tool in combating the COVID-19 pandemic. While their short-term safety and efficacy were demonstrated in clinical trials, rare adverse events, including hemorrhagic strokes, have been reported after widespread use. However, the long-term biodistribution and effects of mRNA vaccines remain underexplored.
This study aimed to investigate the long-term presence of SARS-CoV-2 spike protein in brain tissues of patients with hemorrhagic strokes, examining its potential association with mRNA vaccination.

Methods

A total of 19 cases of hemorrhagic stroke from 2023 to 2024 were retrospectively analyzed. Immunohistochemical staining for SARS-CoV-2 spike protein and nucleocapsid protein was performed on tissue samples. In situ hybridization was conducted in selected cases to confirm the origin of spike protein expression (vaccine or viral infection). Vaccination history and SARS-CoV-2 infection status were documented for all cases.

Results

Spike protein expression was detected in 43.8 % of vaccinated patients, predominantly localized to the intima of cerebral arteries, even up to 17 months post-vaccination. While no active inflammatory changes were identified, infiltration of CD4-, CD8- and CD68- positive cells was observed in the spike protein positive vessels. In situ hybridization confirmed the presence of both vaccine-derived mRNA and SARS-CoV-2 virus-derived mRNA, which encode the spike protein, in select cases. Notably, spike protein positivity was observed exclusively in female patients (P = 0.015). None of the cases showed nucleocapsid protein positivity, supporting the absence of active viral infection.

Conclusion

Although the possibility of spike protein expression due to asymptomatic SARS-CoV-2 infection cannot be entirely excluded, this study demonstrated prolonged presence of SARS-CoV-2 spike protein in the cerebral arteries following mRNA vaccination. Additionally, some inflammatory cell infiltration was observed in spike-positive vessels. These findings raise significant concerns regarding the biodistribution of lipid nanoparticle-based vaccines and their long-term safety. Global replication studies are urgently required to validate these findings and ensure comprehensive safety evaluations of mRNA vaccines.
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**Comment**
While the authors insist that the clot shots provided a critical tool in combating the COVID-19 pandemic, data, a systemic review and reality show otherwise.  In fact in November 2024, a peer-reviewed study called for immediate global moratorium on these experimental gene therapy injections due to unprecedented adverse reactions including death.
They weren’t even tested for reduction in hospitalization, death, or transmission, rather they were tested for reduction in severe symptoms – which is not the proper endpoint for “vaccine” efficacy. To make matters even worse, they dropped the 50% efficacy requirement for Emergency use Authorization (EUA).  Then, they authorized boosters without consulting its vax panel.  Rubberstamping these shots is their modus operandi.

https://slaynews.com/news/who-monkeypox-side-effect-covid-mrna-vaccines/

WHO: ‘Monkeypox’ Is a ‘Side Effect’ of Covid mRNA ‘Vaccines’

The World Health Organization (WHO) has admitted that so-called “monkeypox” is actually a side effect of Covid mRNA “vaccines.”

The United Nations “health” buried the admission on the WHO’s VigiAccess website.

The website contains a database that lists all known side effects of all drugs and vaccines that have been approved for public use.

Under “potential side effects” for the Pfizer BioNTech COVID-19 vaccine, the WHO lists “monkeypox,” “smallpox,” and “cow pox” among hundreds of other disorders.

They are listed under “infections and infestations” that emerge as “side effects” of the Pfizer mRNA vaccine.  (See link for article)

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**Comment**

A new study of WHO data shows that ‘COVID deaths’ skyrocketed among the ‘vaccinated,’ and a study of 9 million also reveals brain damage.

Similarly to COVID, a Monkeypox outbreak followed a ‘Germ-Game’ preparation. A renowned German doctor has already spoken out to warn the public that the monkeypox “outbreak” is a hoax and the “symptoms” are actually side effects of Covid clot shots.  Another doctor states monkeypox is psychological bioterrorism being pushed by ‘evil.’

Take home: these shots are worthless and dangerous.
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