https://www.frontiersin.org/journals/child-and-adolescent-psychiatry/articles/10.3389/frcha.2025.1685016/full

ORIGINAL RESEARCH article

Front. Child Adolesc. Psychiatry, 05 November 2025

Sec. Developmental Psychopathology and Mental Health

Volume 4 – 2025 | https://doi.org/10.3389/frcha.2025.1685016

This article is part of the Research TopicSevere Mental Illnesses in Children: Unravelling Developmental Trajectories, Neuropsychiatric Impairments, and Chronic PainView all 3 articles

Investigating the frequency of tick-borne infections in a case series of 37 youth diagnosed with pediatric bipolar disorder

  • 1Medical Arts Psychotherapy Associates, P.A., Summit, NJ, United States
  • 2Overlook Medical Center, Summit, NJ, United States

Introduction: This retrospective chart review examined 37 youth with pediatric bipolar disorder from a private practice in the Lyme-endemic state of New Jersey, expanding on findings from 27 previously reported cases to explore the potential contribution of tick-borne infections to disease etiology.

Methods: Diagnoses were based on DSM-IV-TR and DSM-V criteria using parent and child interviews, questionnaires, and school reports. Initial screening evaluated for possible PANDAS/PANS, with testing for Group A beta-hemolytic streptococcus, Borrelia burgdorferiBabesiaBartonella, and Mycoplasma pneumoniae. Lyme disease testing included ELISA, Western Blot (IgM/IgG), and immunoblots, interpreted per CDC guidelines. Other pathogens were assessed via IgM/IgG titers, anti-streptolysin O, anti-DNAase B, fluorescent in situ hybridization, and blood cultures. A positive diagnosis required both laboratory evidence and clinician confirmation.

Results: Babesia was detected in 51% (19/37), Bartonella in 49% (18/37), Mycoplasma pneumoniae in 38% (14/37), Borrelia burgdorferi in 22% (8/37), and Group A Streptococcus in 19% (7/37).

Overall, 92% (34/37) had evidence of tick-borne exposure, with 81% (30/37) meeting both laboratory and clinical criteria.

Discussion: More than three-quarters of the cohort demonstrated confirmed tick-borne infections. Overlaps between bipolar disorder and tick-borne illness—such as immune dysregulation, chronic symptomatology, and responsiveness to treatments like minocycline and anti-inflammatory agents—support further exploration of infectious contributors to pediatric bipolar disorder. While limited by its single-practice retrospective design, these findings suggest that tick-borne pathogens may play a role in the pathogenesis of bipolar symptoms in youth, warranting larger, controlled studies.

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https://www.nature.com/articles/s41467-025-64326-w

Open access

Published: 

Targeted volume imaging reveals early vascular interactions of Lyme disease pathogen in skin

Abstract

Although the contours of the dissemination pathways of human pathogenic spirochetes in the vertebrate hosts are known, detailed high-resolution information on these processes remain lacking. In this study, we establish an efficient serial block-face scanning electron microscopy workflow incorporating semi-automatic AI-driven segmentation to investigate the architecture of early events following the deposition of Borrelia burgdorferi at the tick bite site in mice. We capture evidence of Borrelia penetrating the lymphatic endothelium via both transcellular and paracellular routes and observe its early presence within the lumen of the lymphatic vessel. The multistep process of transcellular migration is documented in detail, showing sequential invagination and encasement of shorter Borrelia segments by the lymphatic endothelial cells during intravasation. Our findings reveal that the first contact of B. burgdorferi and blood vessels is not random but involves close interactions with pericytes. We also capture the infiltration of immune cells in the skin and their interactions with invading bacteria. Altogether, these observations suggest that Borrelia strategically targets vascular regions with lower mechanical resistance to breach the endothelial barrier, thereby enhancing its dissemination.

https://www.cureus.com/articles/416304-relative-bradycardia-in-a-61-year-old-male-with-anaplasmosis-a-case-report#!/

Relative Bradycardia in a 61-Year-Old Male With Anaplasmosis: A Case Report

Jessica A. James • Melissa Brown • Samuel M. Segal • Maria Gutierrez-Castillo

Published: October 17, 2025

DOI: 10.7759/cureus.94785 

Peer-Reviewed

Cite this article as: James J A, Brown M, Segal S M, et al. (October 17, 2025) Relative Bradycardia in a 61-Year-Old Male With Anaplasmosis: A Case Report. Cureus 17(10): e94785. doi:10.7759/cureus.94785

Abstract

Human granulocytic anaplasmosis (HGA), or anaplasmosis, is a tick-borne illness caused by Anaplasma phagocytophilum, a gram-negative intracellular bacterium. A. phagocytophilum is primarily transmitted by Ixodes scapularis in the northeast United States and by Ixodes pacificus in California. Presenting symptoms typically include fever, chills, malaise, headache, myalgia, and rarely a rash. This case describes a 61-year-old Black male with a complex medical history, including prior tick-borne and arboviral infections (Lyme disease, dengue fever, and chikungunya), hypertension, mixed hyperlipidemia, bilateral carotid artery dissection, gastroesophageal reflux disease, atrial fibrillation with rapid ventricular response, and current tobacco use. This patient presented to an emergency department in upstate New York with a fever, fatigue, constipation, myalgia, and night sweats. Throughout the patient’s hospital course, he maintained a state of relative bradycardia. The patient reported that he had returned from Haiti and the Dominican Republic two weeks prior to presentation in the emergency department and received several mosquito bites while abroad. Initial guideline-based empiric treatment was started with doxycycline due to suspicion of tick-borne illness, given his history of Lyme disease and his onset of symptoms while in upstate New York. Treatment was continued to complete a 14-day course after confirming the diagnosis of anaplasmosis by PCR testing of whole blood. After completing treatment with doxycycline, the patient’s symptoms resolved completely. This case illustrates a unique finding of relative bradycardia and fever of unknown origin in the context of recent international travel and history of tick-borne and arboviral infections.

 

https://blog.maryannedemasi.com/p/breaking-cdc-quietly-rewrites-its?

BREAKING: CDC quietly rewrites its vaccine–autism guidance

In a stunning shift, the CDC now says its own “vaccines don’t cause autism” claim was not evidence-based.

For the first time in a generation, the US Centres for Disease Control and Prevention (CDC) has rewritten its official position on whether vaccines can cause autism.

This is a change that could reshape one of the most politically charged and emotionally fraught debates in modern medicine.

In a website update published on 19 November 2025, the agency now states that the long-standing claim “vaccines do not cause autism” is “not an evidence-based claim” because scientific studies “have not ruled out the possibility that infant vaccines cause autism.”

The page also acknowledges that “studies supporting a link have been ignored by health authorities.”

It’s difficult to overstate the significance of these statements. For nearly two decades, they would have been unthinkable for a federal public health agency.

The timing is equally striking.

The change arrives at a moment when the political and scientific landscape around vaccine safety is undergoing a marked shift inside the Trump–Kennedy administration.

For months, critics have accused Health Secretary Robert F. Kennedy Jr and several of the administration’s appointees of holding unconventional views on vaccine safety.

The CDC’s revised language now places the agency closer to Kennedy’s long-standing argument that federal agencies had ignored crucial evidence.

The CDC explains the shift by pointing to the Data Quality Act, which requires federal communications to accurately reflect the evidence.

Because studies have not excluded the possibility that infant vaccines could contribute to autism, the agency concedes that its long-standing categorical statement was not scientifically justified.

The update states plainly that scientific uncertainty remains, particularly for vaccines administered in the first year of life. (See link for article)

________________

https://www.midwesterndoctor.com/p/where-does-the-cdcs-dishonesty-come?

Where Does the CDC’s Dishonesty Come From?

Is a new era at last is dawning at the CDC?

Story at a Glance:

  • The widespread promotion of vaccination is predicated upon having profound benefits and no risks. As vaccines frequently injure their recipients, sustaining this paradigm requires suppressing all evidence of vaccine harm and psychologically programming vaccine supporters to be incapable of seeing injuries all around them.
  • Because of this, Senator Ron Johnson held a historic Senate hearing where discarded individuals with vaccine injuries could testify on their injuries.
  • The CDC has consistently used its authority to promote vaccination and support industry (e.g., soft drinks or lucrative therapeutics).
  • In many cases, these promotions have been directly tied to the CDC taking money from industry. Unfortunately, despite both CDC employees and members of Congress demanding investigations, the matter has been largely swept under the rug.
  • The CDC delegates vaccine recommendations to an impartial panel of (paid-off) experts who consistently support vaccination. Recently, RFK Jr. replaced them with scientists free of conflicts of interest.
  • At the first ACIP meeting, the CDC repeated its existing playbook, both making a number of truly remarkable statements defending the COVID vaccine at odds with public data, while simultaneously admitting they did not know numerous fundamental questions about the COVID vaccines that should have been figured out years ago.
  • Fortunately, times have changed, and many immediately saw these lies for what they were. Likewise, yesterday, the CDC made a historic pivot on a longstanding lie and acknowledged stating “vaccines do not cause autism” is a falsehood not supported by the existing evidence.

Important excerpts:

“….CDC corruption is so pervasive that it’s effectively been legalized. For example, a 1983 law authorized the CDC to accept gifts “made unconditionally…for the benefit of the [Public Health] Service or for the carrying out of any of its function,” and in 1992 Congress established A National CDC Foundation, which was quickly incorporated to “mobilize philanthropic and private-sector resources.”

“Since its inception, the CDC Foundation has been accused of egregious conduct and has received nearly 1 billion dollars from corporate “donors”(criticisms include a scathing editorial in one of the world’s top medical journals).

In 2016 CDC employees anonymously complained about this corruption…

….now that their halo of objective expertise has at last been broken (e.g., now only 61% of Americans trust the CDC), we are finally having a chance to seriously scrutinize their absurd claims, and the CDC is nearing the day when it can no longer operate as an unaccountable fiefdom steered by corruption rather than helping the American people. Each time we openly discuss their lies, their power weakens…..

(See link for article)

________________

**Comment**

It’s worth reposting a comment made after the article:

In 1986 the Federal government conceded that all vaccines are unavoidably unsafe, to such an extent that Congress and POTUS codified the (lack of) safety issue within the 1986 Childhood Vaccine Law.

There is no debate to be had since then about vaccine safety or effectiveness. The Feds have stipulated such.

Unavoidably unsafe is Codified.

Let me repeat.

The Federal government acknowledges that the (all) vaccines are so unavoidably unsafe that legal immunity is the ONLY way to protect Bigpharma from CAUSAL lawsuits that would force them to produce ONLY safe and effective vaccines…or go out of business.

Forget the science debate.

Forget the conflicts of interest.

None of that moves the needle.

None of that changes anything.

The 1986 Childhood Vaccine Law is THE prima facie evidence for the lack of safe and effective vaccine manufacturing practices.

The unconstitutional 1986 Law and the associated unlawful Childhood Vaccine Schedule mandate represent the keystone for the public health utilitarianism (aka gotta kill some to save some) ideology. As one or both goes, so does the unavoidably unsafe vaccine.

Either end the mandate or repeal the Law. Thats it. Its that simple. The rest will correct itself.

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Nov. 10, 2025

Chapters:
0:00 Introduction
1:32 Are All These Strange Streaks in the Sky Chemicals Being Released Into the Air?
12:26 Who Is Behind This?
16:09 What Is the Government’s Position on Climate Engineering?
23:42 Weather Control and Operation Popeye
31:47 The US Military’s Role in Climate Engineering
37:14 Why Is Wigington So Dedicated to This Research?
39:05 The Mass Death of Insects and Trees Around the Globe
44:56 The Government’s Biological Warfare Tests on Unknowing Americans 48:01 Wigington’s Meeting With Gavin Newsom
50:28 Is the Government Using Wildfires as a Climate Engineering Weapon?
52:41 Has Congress Ever Attempted to Pass Legislation to Fight This? 57:06 Is Climate Engineering Impacting Earth’s Animal Population?
1:00:30 Where Can People Learn More?
  • According to this, the DOD us using military bases and leased airliners to spray 40-60 MILLION Tons of toxic nanoparticles yearly.
  • According to Dane Wigington, DOD scientist, Dr. Ken Caldera, is on recording stating he ‘designed methods for spreading pathogens into clouds to infect the populations below.’  85 countries were infected with COVID in 3 days and Italian researchers found COVID attached to airbourne particulates indicating COVID was released via air-bourne dispersion.
  • In 1977, the U.S. Army publicly disclosed during Senate hearings that it had conducted 239 open-air biological tests between 1949 and 1969. These experiments released biological simulants—such as bacteria like Serratia marcescens and Bacillus globigii—over populated areas, including cities like San Francisco, New York, and Washington, D.C., to study the spread of potential bioweapons.
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