University of New Haven Professor and Her Students May Have Found a Cure for Lyme Disease

July 07, 2017

Could a common sweetener that’s already in the kitchen cupboards in many American homes — stevia — prove to be an effective treatment for a disease as debilitating and persistent as Lyme disease?

It’s too early to say that for sure, but research by Eva Sapi, a University of New Haven professor of cellular and molecular biology, and the students in her Lyme Disease Research Group looks promising.

In a paper published in the European Journal of Microbiology & Immunology, Eva Sapi and her students found that the most antibiotic resistant form of Borrelia burgdorferi, the bacteria that causes Lyme disease — called biofilm — actually increased in mass with individual antibiotics.

But liquid, whole-leaf stevia extract — not the powdered varieties that people most commonly use — reduced the biofilm mass by about 40 percent, they found.

UNH professor could have cure for Lyme disease

“Is it the one?” Sapi asked. “I don’t know.” But in confirmation test after confirmation test, “that is the one that jumped out.”

A small clinical trial based out of New York got underway just a few months ago, and researchers there are using stevia along with antibiotics to try and treat Lyme disease, while others are taking the extract themselves.

“I’ve got emails from people saying they’re getting better, but again, we need to have double-blind clinical trials before we say ‘yes’. Everybody is holding their breath to see if it helps, and let’s hope for it. That would be wonderful.” 
– Professor Eva Sapi, Ph.D

WFSB 3 CT News (Go to link at top of page for News video)

For more on Stevia:

Study excerpt:

In this study, we provided evidence that Stevia A, as an individual agent, was capable of eliminating the spirochetes and the persisters of Borrelia similar to the reported three-drug combination treatment. Our data also showed that the antibiotics in combination on the persist- ers of Borrelia was indeed consistent with the previous study [30]; this result further confirms the effectiveness of Stevia A.

**Please note Sapi tried numerous forms of Stevia and only some were effective.  The exact Stevia product is not mentioned.  Also, please remember all of this was done in vitro (test tube).  How that plays out in vivo (the human body) has yet to be determined.


In a study using a sugar alcohol, it was reported that xylitol acts as an antiplaque agent by disrupting the formation of biofilms in the oral cavity [54]. In another study, they showed that xylitol affects the production of adhesive polysaccharides of Streptococcus mutans [55].

It was previously shown that sugars prime the uptake of antibiotics in Staphylococcus aureus and Escherichia coli [56]. Based on these previous findings, we hypothesize that Stevia could act as a sugar derivative, which might prime the uptake of the phytochemicals responsible for the antimicrobial effect and, thereby, disrupt the biofilm structure.

I know of certain LLMD’s who use Stevia or Xylitol in their Lyme treatment regimens.  As always, work with your medical professional if you want to try it as some report significant herxes.

In one case, they take 2 tsp of Xylitol once daily along with 500 mg of Lactoferrin.  This regimen tells patients not to use any Stevia/Xylitol related products for the duration of treatment.  Dr. Mary Ross advises starting with 1 drop of Nutramedix brand liquid Stevia twice a day and increasing by 1 drop per dose until at 5 drops twice a day.  Others have stated to build up to 7 drops of Stevia in a glass of water on an empty stomach daily.

Dr. Horowitz has a blog on his Facebook page where patients compare notes on their use of Stevia:



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