Archive for the ‘Ticks’ Category

House Confirms Fiscal Year Spending 2020 For Lyme & Other Vector-Borne Diseases

https://lymediseaseassociation.org/government/federal-government/house-confirms-fiscal-year-spending-2020-for-lyme-and-other-vector-borne-diseases/

House Confirms Fiscal Year Spending 2020 for Lyme & Other Vector-Borne Diseases

The 116th Congress House Committee on Appropriations submitted a report in explanation of bill H.R. 2740, the Omnibus that funds Health and Human Services (HHS) including the National Institute of Health (NIH) and the Centers for Disease Control (CDC), and outlines the final legislative language and designation of funds for vector-borne diseases, including Lyme disease, for fiscal year ending September 30, 2020.

Highlights from the House Explanatory Statement include:

  • The Committee encourages NIAID to intensify research and development on Lyme and other tick-borne diseases, including research that will increase understanding of the full range of processes that cause Lyme disease infection. This should include research on the physiology of Borrelia burgdorferi and Borrelia mayonii, including the mechanisms of possible persistent infection, potential treatment protocols for extended or long-term symptoms attributed to Lyme and other tick-borne diseases, and development of more sensitive and accurate diagnostic tests for Lyme and tick-borne diseases, including next generation polymerase chain reaction (PCR) and new testing methodologies such as proteomics and metabolomics. The Committee directs NIAID to support research on the heightened incidence of Lyme Disease and vector-borne diseases due to global warming.
  • The Committee encourages NIH to improve early diagnosis and treatment of Lyme and other tick-borne diseases (TBD) to prevent the development of late stage disease and more serious and longer-term disability, but also intensify research on diagnosis and treatment of late stage and chronic disease. In addition to development of highly sensitive and specific diagnostics for all stages of disease, a goal should be to develop diagnostics with appropriate sensitivity and specificity for the detection of infection. Treatments also should be developed for all stages of Lyme and other TBD, determining optimal combinations of new candidate or older drugs and exploring novel combinations.

A statement from a Congressional spokesperson further clarifies that, “The agreement includes an increase and encourages CDC, in coordination with NINDS and NIMH, to include in its surveillance the long-term effects. CDC is also encouraged to coordinate with NIH on publishing reports that assess prevention, treatment, diagnostic advancements, and links between tick-borne disease and psychiatric illnesses. CDC is encouraged to focus efforts in endemic areas as well as areas not yet considered endemic.”

Thank you to Congressman Chris Smith (NJ-4) for working with LDA to get some of this language included. Thank you to other advocates and legislators who also provided input into the process.

The CDC received a $2,000,000 increase for Lyme disease.

Click here to view the full H. Rept. 116-62 Explanatory Statement

Click here to view HR 1865 Division A

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**Comment**

The heightened incidence of Lyme disease has nothing to do with “global warming”according to independent Canadian tick researcher John Scott, and is a red herring being used to divert our attention from important issues:  https://madisonarealymesupportgroup.com/2018/11/07/ticks-on-the-move-due-to-migrating-birds-and-photoperiod-not-climate-change/

https://madisonarealymesupportgroup.com/2018/08/13/study-shows-lyme-not-propelled-by-climate-change/

“For blacklegged ticks, climate change is an apocryphal issue.” -John Scott

PLEASE SPREAD THE WORD THAT CLIMATE DATA WILL NOT HELP PATIENTS ONE IOTA.

For an excellent interview with John Scott:  https://madisonarealymesupportgroup.com/2017/08/14/canadian-tick-expert-climate-change-is-not-behind-lyme-disease/ (He also explains the bogus Lyme vaccine as well)

Excerpt:

John explains, “The climate change range expansion model is what the authorities have been using to rationalize how they have done nothing for more than thirty years. It’s a huge cover-up scheme that goes back to the 1980’s. The grandiose scheme was a nefarious plot to let doctors off the hook from having to deal with this debilitating disease. I caught onto it very quickly. Most people have been victims of it ever since.”

“This climate change ‘theory’ is all part of a well-planned scheme. Even the ticks are smarter than the people who’ve concocted this thing,” he says.

“Climate change has nothing to do with tick movement. Blacklegged ticks are ecoadaptive, and tolerate wide temperature fluctuations. On hot summer days, these ticks descend into the cool, moist leaf litter and rehydrate. In winter, they descend into the leaf litter, and are comfortable under an insulating blanket of snow. Ticks have antifreeze-like compounds in their bodies, and can tolerate a wide range of temperatures. For instance, at Kenora, Ontario, the air temperature peaks at 36°C and dips to –44°C, and blacklegged ticks survive successfully.

“Ticks are marvellous eco-adaptors. They will be the last species on the planet. Do you see how silly this theory of climate change is as a way to rationalize what’s happening. It’s all a red herring to divert your attention,” he explains.

Please know that Lyme advocates can also fall prey to the draw of power and money and for some reason good, independent research is being ignored to the peril of patients. Diverting research dollars away from issues like transmission studies, studies for more sensitive and accurate testing, as well as effective treatments has been a ploy of authorities since the beginning. Research has been run by a Cabal who have rife conflicts of interest, controlling the narrative and setting faulty study parameters for a predesignated outcome:  https://madisonarealymesupportgroup.com/2017/01/13/lyme-science-owned-by-good-ol-boys/

https://madisonarealymesupportgroup.com/2019/02/22/why-mainstream-lyme-msids-research-remains-in-the-dark-ages/

Lyme patient and advocate Carl Tuttle writes about this diversion of funds away from important issues needing study such as borrelia persistence and appropriate treatment:  https://www.change.org/p/the-us-senate-calling-for-a-congressional-investigation-of-the-cdc-idsa-and-aldf/u/25690522?

Excerpt:

Per my email below which you were carbon copied on January 31st, wouldn’t it make better sense to fund research into finding a cure for this antibiotic resistant/tolerant superbug instead of financing those with a bias (racketeering scheme) against persistent infection?

NIH Funding: RO1 CK 000152 has been used to suppress evidence of persistent infection while avoiding the horribly disabled Lyme patient community. Isn’t this fraudulent use of taxpayer dollars? So why does it continue under the support of the Centers for Disease Control; an agency under your direct supervision?

https://www.change.org/p/the-us-senate-calling-for-a-congressional-investigation-of-the-cdc-idsa-and-aldf/u/25681241?

Excerpt:

One again we see Dr. Wormser unethically fixated on the acute stage of disease after bulls-eye rash. This does not represent the entire Lyme patient population!

Patients who have had a prolonged exposure to the pathogen and advance to late stage are almost always incapacitated. By avoiding the late stage horribly disabled Lyme patient population, you can perpetuate a forty year racketeering scheme to deny persistent infection.

Patient testimony all across America is describing a disease that is destroying lives, ending careers while leaving its victim in financial ruin.

https://www.change.org/p/the-us-senate-calling-for-a-congressional-investigation-of-the-cdc-idsa-and-aldf/u/25671214?

Excerpt:

The continuous stalling keeps the current dogma and direction intact because a chronic relapsing seronegative disease does not fit the vaccine model.

Direct detection methods have been avoided because they have the potential to identify chronic Lyme.

It’s all about the VACCINE!!!!!! Nothing has changed and the five year NIH STRATEGIC PLAN FOR TICKBORNE DISEASE RESEARCH is written by the same government agency responsible for funding all of the Junk Science aimed at suppressing evidence of persistent infection.
https://www.niaid.nih.gov/sites/default/files/NIH-Strategic-Plan-Tickborne-Disease-Research-2019.pdf

Time to become extremely focused and demand research for issues that will help patients. We don’t need more climate data.

 

 

 

 

 

Non-Anticoagulant Heparin As A Pre-Exposure Prophylaxis Prevents Lyme Disease Infection

https://www.ncbi.nlm.nih.gov/pubmed/31961652/

2020 Jan 30. doi: 10.1021/acsinfecdis.9b00425. [Epub ahead of print]

Non-anticoagulant Heparin as a Pre-exposure Prophylaxis Prevents Lyme Disease Infection.

Abstract

Lyme disease (LD) is caused by the spirochete Borrelia burgdorferi sensu lato (Bbsl). After transmission to humans by ticks, Bbsl spreads to multiple organs, leading to arthritis, carditis, and neuroborreliosis. No effective prophylaxis against human LD prior to tick exposure is currently available. Thus, a pre-exposure prophylaxis (PrEP) against LD is needed. The establishment of LD bacteria at diverse sites is dictated partly by the binding of Bbsl to proteoglycans (PGs) and glycosaminoglycans (GAGs) in tissues. The drug heparin is structurally similar to these GAGs and inhibits Bbsl attachment to PGs, GAGs, cells, and tissues, suggesting its potential to prevent LD. However, the anticoagulant activity of heparin often results in hemorrhage, hampering the development of this compound as LD PrEP.

We have previously synthesized a non-anticoagulant version of heparin (NACH), which was verified for safety in mice and humans. Here, we showed that NACH blocks Bbsl attachment to PGs, GAGs, and mammalian cells. We also found that

  • treating mice with NACH prior to the exposure of ticks carrying Bbslfollowed by continuous administration of this compound prevents tissue colonization by Bbsl.
  • Furthermore, NACH-treated mice develop greater levels of IgG and IgM against Bbsl  at early stages of infection, suggesting that the upregulation of antibody immune responses may be one of the mechanisms for NACH-mediated LD prevention.

This is one of the first studies examining the ability of a heparin-based compound to prevent LD prior to tick exposure. The information presented might also be extended to prevent other infectious diseases agents.

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**Comment**

I found this study fascinating on multiple levels and have had my thoughts on heparin for years due to it helping my husband’s Lyme/MSIDS case substantially.

For whatever reason he developed hyper coagulation (thick blood) after he became infected with tick-borne illness.  I’ve found that many other patients have experienced this as well.  Heparin is used as an anti-coagulant and is often the drug of choice for such patients.  My husband immediately improved on it due hyper coagulation’s ability to make you sluggish and tired as blood flow and oxygen delivery are impeded.  On top of that, thick blood impedes treatment, nutrients from food, and supplements from being distributed and utilized.  It’s a big deal.

The reason we even suspected hyper coagulation in the first place was due to visually seeing it clog blood catheters when he received blood ozone therapy and gave blood.  It looked like bloody snot and caused his blood to be a deep burgundy instead of a bright red.

After years of being on heparin and subsequently needing iron sucrose infusions due to low ferritin, he decided to try going off of it and taking systemic enzymes and fish oil instead.  He’s had no problem going off the heparin.  Read about enzymes here: https://madisonarealymesupportgroup.com/2019/11/18/link-between-inflammation-mental-sluggishness-shown-how-msm-systemic-enzymes-and-melatonin-can-help/  Please read comment section as I explain and have other links to enzymes and other substances which directly help inflammation. Enzymes are known to:

  • mop up debris within the blood
  • prevent and dissolve blood clots by dissolving fibrin
  • break down and remove circulating immune complexes
  • kill pathogens
  • control inflammation
  • improve alkalinity
  • help with detoxification

FYI: fish oil makes the blood more slippery:  https://heartmdinstitute.com/heart-health/is-it-safe-to-mix-fish-oil-and-blood-thinners/

Excerpt & warning when used with other blood thinners and anti-coagulants:

The omega-3 fatty acids in fish oil help make blood platelets less likely to clot; antiplatelet blood thinners do the same thing. Too much of both can increase the risk for excessive bleeding from minor, everyday cuts or from the gastrointestinal side effects of drugs like aspirin or NSAIDs, as well as bruising or injuries that may occur as the result of a fall. Blood that is too thin also raises the risk of hemorrhagic stroke, especially in patients over age 85.

Modest amounts of fish oil, say 1–2 grams daily, generally can be tolerated even if you are taking prescription blood thinners. However, doing this is not without some risk—so it’s absolutely essential that you be up front with your doctor about the fish oil products you’re taking and how much, to avoid unsafe drug interactions. I cannot emphasize this enough. You must work collaboratively with your physician and regularly monitor the clotting agents in your blood.

To read more about heparin:  https://www.mayoclinic.org/drugs-supplements/heparin-intravenous-route-subcutaneous-route/description/drg-20068726  He started out with self-injecting but it’s very painful and causes bruising.  He then used it sub-lingually with similar success and without the negative side effects of injections.

 

 

 

 

 

 

Tick-Borne Spirochetes in Tick & Small Mammals – CA

https://www.ncbi.nlm.nih.gov/pubmed/31943036

2020 Jan 15. pii: tjz253. doi: 10.1093/jme/tjz253. [Epub ahead of print]

Circulation of Tick-Borne Spirochetes in Tick and Small Mammal Communities in Santa Barbara County, California, USA.

Abstract

A diversity of Borrelia burgdorferi sensu lato (Johnson, Schmid, Hyde, Steigerwalt & Brenner) (Spirochaetales: Spirochaetaceae) genomospecies, including the Lyme disease agent, Borrelia burgdorferi sensu stricto (s.s.), have been identified in the western United States. However, enzootic transmission of B. burgdorferi s.l. in small mammals and ticks is poorly characterized throughout much of the region. Here we report prevalence of B. burgdorferi s.l. in small mammal and tick communities in the understudied region of southern California.

We found B. burgdorferi s.l. in 1.5% of Ixodes species ticks and 3.6% of small mammals. Infection was uncommon (~0.3%) in Ixodes pacificus Cooley and Kohls (Acari: Ixodidae), the primary vector of the Lyme disease agent to humans in western North America, but a diversity of spirochetes-including Borrelia bissettiae, Borrelia californiensis, Borrelia americana, and B. burgdorferi s.s.-were identified circulating in Ixodes species ticks and their small mammal hosts.

Infection with B. burgdorferi s.l. is more common in coastal habitats, where a greater diversity of Ixodes species ticks are found feeding on small mammal hosts (four species when compared with only I. pacificus in other sampled habitats). This provides some preliminary evidence that in southern California, wetter coastal areas might be more favorable for enzootic transmission than hotter and drier climates. Infection patterns confirm that human transmission risk of B. burgdorferi s.s. is low in this region.

However, given evidence for local maintenance of B. burgdorferi s.l., more studies of enzootic transmission may be warranted, particularly in understudied regions where the tick vector of B. burgdorferi s.s. occurs.

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**Comment**

Remember – they find ticks on beaches – it doesn’t get much hotter and drier than there.  I know dogs are picking up ticks in the sand dunes of Padre Island, TX – another inferno.  https://madisonarealymesupportgroup.com/2018/06/07/ticks-on-beaches/

Excerpt:

Rosenkranz explained, “Think about it, right now there’s a lot of seagulls and other birds flying and they can carry ticks. People who are walking their dogs they are still allowed to do that they can get a tick that falls off of a dog, it’s pretty common in that sense.”

When it comes to Assateague, ticks can actually fall off the ponies and latch on to you.

Kelly Taylor, an Assistant Public Information Officer at Assateague National Seashore said, “You know you come out, ticks can be on horses so you want to keep your distance from the horses. We always recommend school bus length is the safe length for you, the safe length for the horses.”

And remember, just because ticks are found anywhere in low numbers doesn’t mean they aren’t there and can’t infect you or your pets.

New Tick Threats & Control Tactics – 90 Min. Webinar: Feb. 4, 2020

https://register.gotowebinar.com/register/1996543094261897475  Register Here

NEW TICK THREATS AND CONTROL TACTICS – PANEL DISCUSSION (90-minute webinar)


Tue, Feb 4, 2020 1:00 PM – 2:30 PM CST


This webinar will feature a panel discussion dedicated to the growing threat
posed by ticks and new control tactics to address this expanding pest. Webinar participants will be able to pose questions, in real time, to a panel of entomologists
and other related experts who understand the health concerns posed by ticks to
individuals and their pets. Seize on this opportunity to ask experts about the newest tick
prevention and control measures. EPA is committed to protecting the privacy
and security of the information it holds. By clicking the “Register” button, you agree
to receive emails from EPA regarding this webinar. In addition, you consent to allow
EPA to use your information, in aggregate, to report on webinar attendance and participant demographics. EPA will not share your
information with any outside entities.
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Tick Paralysis in a Free-ranging Bobcat

https://avmajournals.avma.org/doi/abs/10.2460/javma.256.3.362?journalCode=javma

Abstract
February 1, 2020, Vol. 256, No. 3, Pages 362-364

Tick paralysis in a free-ranging bobcat (Lynx rufus)

Meredith E. Persky DVM1; Yousuf S. Jafarey DVM1; Sarah E. Christoff​‌1; Dewey D. Maddox​‌1; Stephanie A. Stowell​‌2 and Terry M. Norton DVM23
1Department of Animal Health, Jacksonville Zoo and Gardens, 370 Zoo Pkwy, Jacksonville, FL 32218. (); 2Georgia Sea Turtle Center, 214 Stable Rd, Jekyll Island, GA 31527. (); 3Jekyll Island Authority, 100 James Rd, Jekyll Island, GA 31527. ()
Address correspondence to Dr. Persky ().

 

CASE DESCRIPTION

A free-ranging male bobcat (Lynx rufus) was evaluated because of signs of pelvic limb paralysis.

 

CLINICAL FINDINGS

Physical examination of the anesthetized animal revealed tick infestation, normal mentation, and a lack of evidence of traumatic injuries. Radiography revealed no clinically relevant abnormalities. Hematologic analysis results were generally unremarkable, and serologic tests for exposure to feline coronavirus, FeLV, FIV, and Toxoplasma gondii were negative. Results of PCR assays for flea- and common tick-borne organisms other than Bartonella clarridgeiae were negative.

 

TREATMENT AND OUTCOME

Ticks were manually removed, and the patient received supportive care and fipronil treatment. The bobcat made a full recovery within 72 hours after treatment for ticks, and a presumptive diagnosis of tick paralysis was made. Identified tick species included Dermacenter variabilis, Amblyomma americanum, and Ixodes scapularis.

 

CLINICAL RELEVANCE

To the authors’ knowledge, tick paralysis has not previously been reported in felids outside Australia. This disease should be considered a differential diagnosis in felids, including exotic cats, with signs of neuromuscular disease of unknown etiopathogenesis.