Archive for the ‘research’ Category

New Research Shows Majority May Already Have Resistance to COVID-19

https://off-guardian.org/2020/06/12/study-80-of-people-naturally-resistant-to-coronavirus/

STUDIES: 60% of people naturally RESISTANT to SARS-COV2 New research suggests majority of people may already have resistance based on previous infections

OffG

June 12, 2020

A new study has found that Sars-Cov-2, the virus linked to Covid19, maybe five times more widespread than previously thought, and therefore five times less deadly.

The research, conducted by a team of scientists at the University Hospital in Zurich, is titled: “Systemic and mucosal antibody secretion specific to SARS-CoV-2 during mild versus severe COVID-19”, and found that Sars-Cov-2-specific antibodies only appear in the most severe cases, or about 1 out of 5.

____________________

**Comment**

Important quote:

Importantly, we detected SARS-CoV-2-reactive CD4+ T cells in ∼40%–60% of unexposed individuals, suggesting cross-reactive T cell recognition between circulating “common cold” coronaviruses and SARS-CoV-2.

The important take-away is that there is a close relationship between coronaviruses which are harmless to most but unfortunately can be severe, especially those with comorbidities.

For more:  https://madisonarealymesupportgroup.com/2020/04/06/wheres-the-evidence-supporting-the-drastic-measures-against-covid-19/

https://madisonarealymesupportgroup.com/2020/04/28/er-doctors-go-over-covid-19-statistics-why-are-we-in-lockdown-also-a-lesson-on-immunity/

https://madisonarealymesupportgroup.com/2020/06/06/lockdown-lunacy-the-thinking-persons-guide/

https://madisonarealymesupportgroup.com/2020/06/10/infectivity-of-asymptomatic-sars-cov-2-carriers-is-weak/

https://madisonarealymesupportgroup.com/2020/04/19/swedish-epidemiologist-lockdowns-are-not-evidence-based/

https://madisonarealymesupportgroup.com/2020/06/03/testing-for-covid-19-neither-necessary-nor-effective-covid-19-on-its-way-out/

 

 

Category:

research, Testing, Viruses

Oral Penicillin For Lyme Patients With EM Rash in the U.S.

https://pubmed.ncbi.nlm.nih.gov/32473319/?

. 2020 Apr 28;97(4):115071.

doi: 10.1016/j.diagmicrobio.2020.115071.Online ahead of print.

Evaluation of the Role of Oral Penicillin for Treating Lyme Disease Patients With Erythema Migrans in the United States

Gary P Wormser 1, Franc Strle 2
Affiliations

Abstract

Clinical trials of oral penicillin preparations in the United States for treating Lyme disease patients with erythema migrans are limited to 2 studies. The results of these studies demonstrated a less than optimal outcome of this treatment. However, there were serious methodologic concerns in both studies precluding the interpretation that phenoxymethylpenicillin specifically should be regarded as ineffective. Therefore, additional clinical trials should be conducted in the United States with close attention to the dose and duration of treatment that have been used very successfully in Europe.

____________________

**Comment**

I got news for you: there are serous methodologic concerns with most studies on Lyme – particularly regarding treatment. To hear it from the very people in charge of those studies is a bit like the pot calling the kettle black.

The next all important question is why are they even attempting to treat the rash?  The rash is just an outward sign of a inner systemic infection and just because you eliminate the rash doesn’t mean the inner systemic infection is gone.  So, no, we don’t need more research on this.  What we need is research on how to clear the infection once and for all.  Please note Wormser and Strle are behind this continuing focus on the rash and the acute phase of Lyme.

Move on gentlemen, this is a waste of money and time, and doesn’t help patients one iota.  

Category:

Lyme, research, Treatment

Formidable Evidence For Sexual Transmission of Lyme Disease – First Study to Document ACA Rashes in Canadian Patients

healthcare-08-00157-v2 Full study Here

Presentation of Acrodermatitis Chronica Atrophicans Rashes on Lyme Disease Patients in Canada

John D. Scott

International Lyme and Associated Diseases Society, 2 Wisconsin Circle, Suite 700, Chevy Chase, MD 20815-7007, USA; jkscott@bserv.com; Tel.: +1-519-843-3646 Received: 13 May 2020; Accepted: 29 May 2020; Published: 4 June 2020

Abstract:

Lyme disease (Lyme borreliosis) is a complex multisystem illness with varying clinical manifestations. This tick-borne zoonosis is caused by the spirochetal bacterium, Borrelia burgdorferi sensu lato (Bbsl) and, worldwide, presents with at least 20 different types of rashes. Certain cutaneous rashes are inherently interconnected to various stages of Lyme disease. In this study, five Canadian Lyme disease patients from a multi-age range presented various phases of the acrodermatitis chronica atrophicans (ACA) rash. In each case of ACA, the underlying etiological pathogen was the Lyme disease spirochete. Although ACA rashes are normally found on the lower extremities, this study illustrates that ACA rashes are not directly correlated with a tick bite, geographic area, age, Bbsl genospecies, exercise, or any given surface area of the body.

  • Case 4 provides confirmation for an ACA rash and gestational Lyme disease (club feet at birth).  Both parents tested positive for Bbsl.
  • One patient (Case 5) puts forth a Bbsl and Bartonella sp. co-infection with a complex ACA rash.
This study documents ACA rashes on Lyme disease patients for the first time in Canada.

**Comment**

The study states that about 63% of patients infected with Lyme develop chronic Lyme disease.  Authorities keep telling us it’s only 10-20%. It also states Lyme colonizes in many immune-privileged sides including bone, brain, eye, ligaments & tendons, heart, kidney, bladder, liver, muscle, synovial cells, central nervous system, claim and neuronal cells, and fibroblasts/scar tissue.  It states Lyme can be an insidious neurologic pathogenesis with demyelination, and even fatal.

The study points out that Bb is pleomorphic with diverse forms (spirochetes, round bodies, blebs, granules, and biofilms). The study also touches upon the hopelessness many patients can experience which can lead to despair and suicide. Lyme may be potentially transmitted via intimate relations as well as gestationally.

For more:  

Rashes-larger-blog-4Various studies showing how many get the EM rash.

Category:

Bartonella, Lyme, research, Testing

Infectivity of Asymptomatic SARS-CoV-2 Carriers is Weak

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219423/

. 2020 Aug; 169: 106026.
Published online 2020 May 13. doi: 10.1016/j.rmed.2020.106026
PMCID: PMC7219423
PMID: 32405162

A study on infectivity of asymptomatic SARS-CoV-2 carriers

Ming Gao,a,1 Lihui Yang,b,1 Xuefu Chen,c Yiyu Deng,d Shifang Yang,e Hanyi Xu,e Zixing Chen,e and Xinglin Gaoe,∗
Author information Article notes Copyright and License information Disclaimer
Associated Data

Abstract

Background

An ongoing outbreak of coronavirus disease 2019 (COVID-19) has spread around the world. It is debatable whether asymptomatic COVID-19 virus carriers are contagious. We report here a case of the asymptomatic patient and present clinical characteristics of 455 contacts, which aims to study the infectivity of asymptomatic carriers.

Material and methods

455 contacts who were exposed to the asymptomatic COVID-19 virus carrier became the subjects of our research. They were divided into three groups: 35 patients, 196 family members and 224 hospital staffs. We extracted their epidemiological information, clinical records, auxiliary examination results and therapeutic schedules.

Results

The median contact time for patients was four days and that for family members was five days. Cardiovascular disease accounted for 25% among original diseases of patients. Apart from hospital staffs, both patients and family members were isolated medically. During the quarantine, seven patients plus one family member appeared new respiratory symptoms, where fever was the most common one. The blood counts in most contacts were within a normal range. All CT images showed no sign of COVID-19 infection. No severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections was detected in 455 contacts by nucleic acid test.

Conclusion

In summary, all the 455 contacts were excluded from SARS-CoV-2 infection and we conclude that the infectivity of some asymptomatic SARS-CoV-2 carriers might be weak.

_____________________

**Comment**

A sample of 455 people is nothing to sniff at.

But, similarly to the face-mask issue, the WHO is waffling.  After saying asymptomatic spread is very rare, they now state there’s still too much that’s unknown.  Still, 455 people exposed to an asymptomatic carrier and not one got ill says a lot.

For more:  https://madisonarealymesupportgroup.com/2020/06/06/lockdown-lunacy-the-thinking-persons-guide/

https://madisonarealymesupportgroup.com/2020/06/01/real-covid-19-data-leaked-report/

https://madisonarealymesupportgroup.com/2020/04/11/hospitals-paid-extra-to-list-patients-as-covid19-3x-as-much-if-the-patient-is-on-a-ventilator/

https://madisonarealymesupportgroup.com/2020/06/02/successful-covid-19-critical-care-stonewalled-by-cdc/

https://madisonarealymesupportgroup.com/2020/05/27/cloth-masks-useless-against-covid-19/

https://madisonarealymesupportgroup.com/2020/05/15/social-distancing-is-snake-oil-not-science/

https://madisonarealymesupportgroup.com/2020/05/16/we-could-open-up-again-and-forget-the-whole-thing/

https://madisonarealymesupportgroup.com/2020/05/24/do-lockdowns-work-mounting-evidence-says-no/

Comic relief

http://

Why the Lockdowns Should Last Longer

Here’s why the lockdown should never end. In the global pandemic the lockdown has been used and extended. Many think it should end. Here’s why they’re wrong and it should potentially never end.

 

Category:

research, Viruses

Emerging Tick-Borne Diseases & Blood Safety: Summary of a Public Workshop

https://pubmed.ncbi.nlm.nih.gov/32208532/

. 2020 Mar 24.

doi: 10.1111/trf.15752. Online ahead of print.

Emerging Tick-Borne Diseases and Blood Safety: Summary of a Public Workshop

Krishna V K Mohan 1, David A Leiby 1
Affiliations expand

Abstract

Tick-borne agents of disease continue to emerge and subsequently expand their geographic distribution. The threat to blood safety by tick-borne agents is ever increasing and requires constant surveillance concomitant with implementation of appropriate intervention methods. In April 2017, the Food and Drug Administration organized a public workshop on emerging tick-borne pathogens (excluding Babesia microti and Lyme disease) designed to provide updates on the current understanding of emerging tick-borne diseases, thereby allowing for extended discussions to determine if decisions regarding mitigation strategies need to be made proactively. Subject matter experts and other stakeholders participated in this workshop to discuss issues of biology, epidemiology, and clinical burden of tick-borne agents, risk of transfusion-transmission, surveillance, and considerations for decision making in implementing safety interventions. Herein, we summarize the scientific presentations, panel discussions, and considerations going forward.

____________________

**Comment**

I only had access to the abstract, but Dr. Cameron writes more fully on the workshop here:  https://danielcameronmd.com/babesia-infection-transmitted-blood-supply/

Interestingly, according to the abstract, they excluded Babesia and Lyme, which are arguably two of the largest problems. It was pointed out that 200 cases of Babesia were transmitted through blood transfusions at the time of the workshop and that Anaplasma is next with increasing clinical cases.

Evidently there have been no reported cases of Lyme transmitted through the blood supply.

 

Other tick-borne pathogens have been transmitted through donated blood, but these occurrences are rare. (Or rarely reported)

  • 11 cases: A. phagocytophilum, responsible for Anaplasmosis (transmitted by the Ixodes ticks)
  • 2 cases: Tick-borne encephalitis virus complex (TBEV, Powassan virus, DTV), (transmitted by the Ixodes ticks)
  • 1 case: Colorado tick-fever virus (transmitted by Rocky Mountain wood ticks)
  • 1 case: Rickettsia rickettsii, the agent of Rocky Mountain Spotted Fever (transmitted by the Lone Star tick)
  • 1 case: Ehrlichia ewingii (transmitted by the Lone Star tick)

In addition, “two emerging [tick-borne agents] − B. miyamotoi and Powassan virus were discussed − for B. miyamotoi,cases have steadily increased since 2014.”

For more:  https://madisonarealymesupportgroup.com/2019/07/28/tick-borne-infection-risk-in-blood-transfusion/

https://madisonarealymesupportgroup.com/2018/10/11/transfusion-transmitted-babesiosis-one-states-experience/

https://madisonarealymesupportgroup.com/2017/08/08/transfusion-transmitted-babesiosis-in-nonendemic-areas/

https://madisonarealymesupportgroup.com/2019/05/26/fda-recommends-testing-for-tick-borne-illness-in-donated-blood-a-big-duh/

https://madisonarealymesupportgroup.com/2016/06/02/study-showing-results-testing-babesia-microti/

 

Category:

Anaplasmosis, Babesia, Ehrlichiosis, Lyme, research, Rickettsia, Rocky Mountain Spotted Fever, Testing, Transmission, Viruses