Archive for the ‘research’ Category

Study Shows Lyme, Helicobacter Pylori, and Cytomegalovirus Are Risk Factors for All-Cause Mortality in the Elderly

https://pubmed.ncbi.nlm.nih.gov/32648237/

. 2020 Jul 9.

doi: 10.1007/s11357-020-00216-x. Online ahead of print.

Seropositivity for pathogens associated with chronic infections is a risk factor for all-cause mortality in the elderly: findings from the Memory and Morbidity in Augsburg Elderly (MEMO) Study

Marius Zeeb123, Tobias Kerrinnes3, Luka Cicin-Sain4567, Carlos A Guzman4, Wolfram Puppe578, Thomas F Schulz578, Annette Peters19, Klaus Berger10, Stefanie Castell3, André Karch11

Abstract

Immunostimulation by chronic infection has been linked to an increased risk for different non-communicable diseases, which in turn are leading causes of death in high- and middle-income countries. Thus, we investigated if a positive serostatus for pathogens responsible for common chronic infections is individually or synergistically related to reduced overall survival in community dwelling elderly. We used data of 365 individuals from the German MEMO (Memory and Morbidity in Augsburg Elderly) cohort study with a median age of 73 years at baseline and a median follow-up of 14 years. We examined the effect of a positive serostatus at baseline for the following selected pathogens associated with chronic infections on all-cause mortality with multivariable parametric survival models:

  • Helicobacter pylori
  • Borrelia burgdorferi sensu lato
  • Toxoplasma gondii
  • cytomegalovirus
  • Epstein-Barr virus
  • herpes simplex virus 1/2, and human herpesvirus 6

We found a reduced survival time in individuals with a positive serostatus for the following pathogens after adjusting for potential confounders:

  • Helicobacter pylori (accelerated failure time (AFT) – 15.92, 95% CI – 29.96; – 1.88)
  • cytomegalovirus (AFT – 22.81, 95% CI – 36.41; – 9.22)
  • Borrelia burgdorferi sensu lato (AFT – 25.25, 95% CI – 43.40; – 7.10)
The number of infectious agents an individual was seropositive for had a linear effect on all-cause mortality (AFT per additional infection – 12.42 95% CI – 18.55; – 6.30).

Our results suggest an effect of seropositivity for Helicobacter pylori, cytomegalovirus, and Borrelia burgdorferi sensu lato on all-cause mortality in older community dwelling individuals. Further research with larger cohorts and additional biomarkers is required, to assess mediators and molecular pathways of this effect.

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**Comment**

Recently I posted this article and that Cytomegalovirus, EBV, and Herpes Virus 6 has been found in those with ME/CFS:  https://madisonarealymesupportgroup.com/2020/07/23/cytomegalovirus-ebv-and-human-herpesvirus-6-infections-in-patients-with-me-cfs/

Some have been misdiagnosed with EBV but had Lyme:  https://madisonarealymesupportgroup.com/2017/04/11/diagnosed-with-ebv-had-lyme/

Dr. Waisbren, an IDSA founder and Wisconsin Doctor found that his Lyme patients often had high EBV titers:  https://madisonarealymesupportgroup.com/2017/07/09/idsa-founder-used-potent-iv-antibiotics-for-chronic-lyme/

Another important finding: The more pathogens a patient tested positive for, the higher the mortality, demonstrating that coinfected patients are sicker.

 

 

 

 

Category:

Lyme, research, Viruses

Possible Role for Ascorbic Acid in COVID-19

A Possible Role for Ascorbic Acid in COVID-19

Jorge R Miranda-Massari
Michael J Gonzalez
Víctor A. Marcial-Vega
Jorge Duconge Soler

pdf here: A_Possible_Role_for_Ascorbic_Acid_in_COVID-19

Excerpt:

IV ascorbic acid has a long track record of safety. It has been used historically in the management of viral infections and more recently for sepsis. Ongoing clinical trials in the United States, Canada, China, Italy, and other countries will hopefully support its widespread use for patients with COVID-19 infection in the larger medical community. (See pdf link for entire paper)

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For more:  https://madisonarealymesupportgroup.com/2020/06/15/the-functional-medicine-approach-to-covid-19-virus-specific-nutraceutical-botanical-agents/

https://madisonarealymesupportgroup.com/2020/05/08/natural-supplements-vs-coronaviruses/

https://madisonarealymesupportgroup.com/2020/03/20/herbal-treatment-for-covid-19-addendum-buhner/

https://madisonarealymesupportgroup.com/2020/07/13/nutritional-supplements-for-covid-19-prophylaxis-and-symptom-de-escalation/

https://madisonarealymesupportgroup.com/2020/04/11/85-covid-patients-zero-hospitalizations-no-deaths/

https://madisonarealymesupportgroup.com/2020/06/02/successful-covid-19-critical-care-stonewalled-by-cdc/?

https://madisonarealymesupportgroup.com/2020/06/26/math-protocol-shows-profound-impact-on-survival-from-covid-19/

https://madisonarealymesupportgroup.com/2020/05/22/new-study-hcq-zinc-greatly-reduces-covid-19-health-risk/

In short, COVID is a virus, which means the stronger your body is the more powerfully it can fight to keep you healthy.  Lyme/MSIDS patients have to learn this simple truth in their journey.  If there’s a silver lining in the COVID debacle, it’s that the general population has an opportunity to become educated on health – IF and only IF they do not accept the COVID narrative that is being spun by ‘authorities,’  which essentially is – cower in fear, wear a mask, and wait for our lucrative vaccine.

These ‘authorities’ are the same ones behind the Lyme/MSIDS debacle, following the same narrative: malign everyone else’s tests and treatments and bully doctors into only using things ‘authorities’ approve of.  

I recently posted a paper by none other than Dr. Fauci himself who insists that “Big Science” is the only way to go – sending a clear message to doctors.

Chris Newton explains it here:  https://www.linkedin.com/pulse/god-precious-randomized-control-trials-rcts-chris-newton/?

My husband and I and thousands of Lyme/MSIDS patients would be dead if it weren’t for doctors willing to treat us without those precious randomized controlled trials.  Right now there are thousands of Lyme/MSIDS patients being treated with Disulfiram/Antabuse based mainly upon 3 case studies and clinical experience.  Many of which are finally getting their health back after decades of suffering.

 

 

Category:

Herbs, research, Supplements, Treatment, Viruses

Researchers Investigating Possible Link Between Vitamin D Deficiency and COVID-19

https://www.azcentral.com/story/news/local/arizona-science/2020/07/22/coronavirus-research-study-link-between-vitamin-d-deficiency-covid-19/

Researchers investigating possible link between vitamin D deficiency and COVID-19

Amanda Morris

Arizona Republic
Southwest College of Naturopathic Medicine lab technician Beverly McCall takes a sample of blood from a COVID-19 clinical study participant.

For months, many of us have stayed home on the advice of health experts, quarantining indoors to help slow the spread of the coronavirus. Now some researchers are investigating the possibility that spending a little more time in the sun could actually help prevent COVID-19.

That’s because sunshine is a key ingredient for our bodies to make vitamin D. 

After seeing a correlation between severe COVID-19 patients and vitamin D deficiency, the researchers hypothesized that the vitamin, absorbed through sunlight by the skin, could play a role in helping the body’s immune system fight the novel coronavirus. (See link for article)

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**Comment**

I posted on this back in April and considered it common sense, but I’m discovering common sense isn’t so common.  https://madisonarealymesupportgroup.com/2020/04/09/you-are-safer-outside-than-inside-disease-expert-criticizes-restrictions/

The article discusses a study of nearly 500 patients and found those with vitamin D deficiencies were nearly twice as likely to test positive for COVID.  I’m not impressed with these findings because the tests are abysmal and not to be trusted..  Plus, testing positive means nothing as you may never even develop symptoms.

What’s important is the  correlation between COVID severity and vitamin D deficiency.

This review https://onlinelibrary.wiley.com/doi/full/10.1111/apt.15777 found:

“When mortality per million is plotted against latitude, it can be seen that all countries that lie below 35 degrees North have relatively low mortality. Thirty‐five degrees North also happens to be the latitude above which people do not receive sufficient sunlight to retain adequate vitamin D levels during winter. This suggests a possible role for vitamin D in determining outcomes from COVID‐19 …

What is helpful in the article is that it reminds the reader that we make less vitamin D as we age and those with darker skin tones (higher melanin content) block UV rays which are required to make vitamin D.  This may explain COVID severity in the black population and why it’s imperative to know your vitamin D levels and to either get sun or supplement.  For those of us in the North, we can’t achieve the amount of sunlight necessary for most of the year and supplementation is required for us to have appropriate vitamin D levels.  Make sure you test before you supplement.

The article goes on to mention a study that showed the following percentages are at risk of low vitamin D

  • 21% of whites
  • 42% of hispanics
  • 73% of blacks

Interestingly, they state the higher rate of vitamin D deficiency in overweight people is due to the fact D is dissolved in fat and isn’t getting into the blood stream.  Another reason to keep your ideal weight.

I will add that not only is sunlight invaluable and the only way to increase vitamin D levels naturally, fresh air (oxygen) unimpeded by masks is also healthy..

Similarly to the attack on HCQ, ‘authorities’ are also coming down on vitamin D:  https://madisonarealymesupportgroup.com/2020/07/02/experts-criticize-government-review-of-vitamin-d-for-covid-19/

Here’s another example of misinformation:  https://articles.mercola.com/sites/articles/archive/2020/06/08/cnn-coronavirus-vitamin-d  Within this link Dr. Mercola highly advises you get your vitamin D levels optimal before fall and the seasonal flu.

That’s not to say there aren’t things to know.  Since Vitamin D is a fat soluble vitamin, it’s important to check your levels at least yearly.  For a great read on D and everything you need to know:  https://madisonarealymesupportgroup.com/2018/03/12/the-importance-of-vitamin-d-k-and-magnesium-for-lyme-msids-patients/

Category:

research, Supplements, Viruses

Paper Claiming 5G Induces Coronavirus in Skin Cells Silently Removed

https://scienceintegritydigest.com/2020/07/23/worst-paper-of-2020-5g-and-coronavirus-induction/

By Elisabeth Bik, for Harbers-Bik LLC.

Worst paper of 2020? 5G and Coronavirus induction

This paper made my jaw drop:

5G Technology and induction of coronavirus in skin cells – M Fioranelli et al. – J Biol Regul Homeost Agents 2020 Jul 16;34(4). doi: 10.23812/20-269-E-4.

The paper suggests that 5G waves (the latest cell phone technology) can spontaneously generate Coronaviruses in skin cells. Yet, there is nothing in this article that proves this extraordinary claim. It is absolute nonsense. (See link for article)

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**Comment**

Evidently the paper is removed from the journal’s website and after outrage, the journal silently removed it altogether – but the DOI link now leads to the wrong paper with a different DOI, which is problematic.  It it’s erroneous it needs to be retracted.

The plot continues to thicken…..

5G; however, definitely causes COVID-like symptoms:

https://madisonarealymesupportgroup.com/2020/05/06/evidence-of-5g-health-effects-mounts/

 

 

 

 

Category:

Activism, research, Viruses

Retraction to SARS-CoV-2 Article: Should Have Used Primary T Cells Instead of T-Cell Lines

https://www.nature.com/articles/s41423-020-0498-4?

Retraction Note to: SARS-CoV-2 infects T lymphocytes through its spike protein-mediated membrane fusion

Xinling Wang, Wei Xu, Gaowei Hu, Shuai Xia, Zhiping Sun, Zezhong Liu, Youhua Xie, Rong Zhang, Shibo Jiang & Lu Lu

Cellular & Molecular Immunology (2020)Cite this article

The original article was published on 07 April 2020

Retraction to: Cellular & Molecular Immunology https://doi.org/10.1038/s41423-020-0424-9, published online 7 April 2020

The authors have retracted this article1. After the publication of this article, it came to the authors attention that in order to support the conclusions of the study, the authors should have used primary T cells instead of T-cell lines. In addition, there are concerns that the flow cytometry methodology applied here was flawed. These points resulted in the conclusions being considered invalid.

[All authors agree with this retraction]

References

1. Wang, X., Xu, W., Hu, G. et al. SARS-CoV-2 infects T lymphocytes through its spike protein-mediated membrane fusion. Cell Mol. Immunol. https://doi.org/10.1038/s41423-020-0424-9 (2020).

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**Comment**

Cell lines offer an easy, inexpensive and stable platform. However, they often do not fully represent what is occurring in vivo. If you want to model the complex physiological behavior, human primary cells would be the better choice.  https://www.promocell.com/in-the-lab/human-primary-cells-and-immortal-cell-lines/

Interestingly, the initial research paper that implicated how the novel coronavirus might infect white blood cells akin to HIV has been described as the splashiest article to date for the journal and only took 3 days to be accepted.  It took over two MONTHS to be retracted but continued to get noticed and shared.  Leonardo Ferreira, Molecular Immunologist and Human Genome Engineer writes:

While I applaud the openness of the authors and the editor, what kind of system is this where it takes more than 20 times longer to amend the scientific record than to publish flawed articles?  https://retractionwatch.com/2020/06/15/a-journal-took-three-days-to-accept-a-covid-19-paper-its-taken-two-months-and-counting-to-retract-it/

Ferreira brings up a valid point – especially in a time of panic and overreaching governmental sanctions based on ‘science.’  I can’t tell you how many letters of reply I’ve received back from Wisconsin politicians stating they are just ‘following the science.’  I write them back and explain they are following popular propaganda, and they need to realize there are authorities with hidden agendas using ‘science’ and even creating ‘science’ to buttress their own narrative.

I sincerely pray the public wakes up and becomes educated on this very important issue before we find ourselves locked away at home with ankle bracelets on.

Authorities are also suppressing effective treatments such as the MATH+ protocol, HCQ with zinc and azithromycin, and a viral protocol of taking vitamins A, C, D, and Iodine: 

I think this quote explains why these inexpensive treatments have been suppressed:

“Quarantines are not great to experience and certainly not popular. But they buy us — and especially the researchers working on medication and vaccination — crucial time,” the narrator assures viewers. “So if you are under quarantine, you should understand why and respect it.”  https://madisonarealymesupportgroup.com/2020/04/06/wheres-the-evidence-supporting-the-drastic-measures-against-covid-19/

Our ‘authorities’ are pushing lucrative experimental vaccines and the very expensive anti-viral, Remdesivir – both of which they have financial interests in.

Then, because he can, Fauci recently writes up a paper stating that only randomized controlled trials are reliable and that non-randomized, observations trials, are essentially wasting time.  Chris Newton explains it here:  https://www.linkedin.com/pulse/god-precious-randomized-control-trials-rcts-chris-newton/?

My husband and I and thousands of Lyme/MSIDS patients would be dead if it weren’t for doctors willing to treat us without those precious randomized controlled trials.  This is why doctors go to school and why ‘authorities’ like Fauci are an enemy to Lyme patients.  He and others in high places vilify doctors who treat outside the box of their acceptability – and by vilify, I mean come after their medial licenses, fine them, and often put them out of business.

I’ve posted this before, but there is a similarity in how they’ve treated COVID and Lyme:  https://madisonarealymesupportgroup.com/2020/04/26/cdc-playbook-learning-from-lyme/  In it we learn the CDC insists upon using its own tests (even when they are horribly inaccurate), treatments (even if they are cost prohibitive), vaccines,and maligns anyone who opposes this dictatorship. I’ve seen it first-hand.

What’s truly sad about this is that people are dying – from both diseases, yet the CDC cares more about owning the patents on tests, treatments, and vaccines than they do about patient care. Health dictators like Fauci would rather sit on an ivory tower directing every aspect of a disease rather than humbly ask doctors who are having success how they do it and then utilizing their life-saving protocols.  This has happened in the Lyme world for over 40 years and is now taking place with COVID.

 Time to wake up and admit our ‘authorities’ care more about profit than patients.

 

Category:

Activism, research, Viruses