Bartonella Found in Dogs After Infection With Rickettsia

January 11, 2020

https://www.ncbi.nlm.nih.gov/pubmed/31891215/

2019 Dec 31. doi: 10.1111/jvim.15675. [Epub ahead of print]

Detection of Bartonella spp. in dogs after infection with Rickettsia rickettsii.

Lashnits E1, Neupane P2, Maggi RG2,3, Linder KE4, Bradley JM2, Balakrishnan N3, Southern BL5, McKeon GP2,5, Chandrashekar R6, Breitschwerdt EB2,3.

Abstract

BACKGROUND:

Dynamics of infection by Bartonella and Rickettsia species, which are epidemiologically associated in dogs, have not been explored in a controlled setting.

OBJECTIVES:

Describe an outbreak investigation of occult Bartonella spp. infection among a group of dogs, discovered after experimentally induced Rickettsia rickettsii (Rr) infection.

ANIMALS:

Six apparently healthy purpose-bred Beagles obtained from a commercial vendor.

METHODS:

Retrospective and prospective study. Dogs were serially tested for Bartonella spp. and Rr using serology, culture, and PCR, over 3 study phases: 3 months before inoculation with Rr (retrospective), 6 weeks after inoculation with Rr (retrospective), and 8 months of follow-up (prospective).

RESULTS:

Before Rr infection, 1 dog was Bartonella henselae (Bh) immunofluorescent antibody assay (IFA) seroreactive and 1 was Rickettsia spp. IFA seroreactive. After inoculation with Rr, all dogs developed mild Rocky Mountain spotted fever compatible with low-dose Rr infection, seroconverted to Rickettsia spp. within 4-11 days, and recovered within 1 week. When 1 dog developed ear tip vasculitis with intra-lesional Bh, an investigation of Bartonella spp. infection was undertaken. All dogs had seroconverted to 1-3 Bartonella spp. between 7 and 18 days after Rr inoculation. Between 4 and 8 months after Rr inoculation, Bh DNA was amplified from multiple tissues from 2 dogs, and Bartonella vinsonii subsp. berkhoffii (Bvb) DNA was amplified from 4 of 5 dogs’ oral swabs.

CONCLUSIONS AND CLINICAL IMPORTANCE:

Vector-borne disease exposure was demonstrated in research dogs from a commercial vendor. Despite limitations, our results support the possibilities of recrudescence (reappearance) of chronic subclinical Bartonella spp. infection after Rr infection and horizontal direct-contact transmission between dogs.

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**Comment**

Bartonella isn’t even on most GP’s radar, yet patients with tick-borne illness often have it.  This dog study shows how Bartonella can be chronic, subclinical, and reactivated by other pathogens.  Subclinical can mean a few things – either the patient appears asymptomatic (without symptoms) or it isn’t picked up on testing or both.

This issue highlights an important field of study that’s begging to be done.

Does a tick bite lower the immune system so that what was a subclinical issue now triggers an active infection?  It makes sense that a tick bite would do this, as vaccines have been shown to do this. Vaccines are designed to lower the immune system so the body mounts an immune response and creates antibodies to whatever is in the vaccine.

Dr. Burrascano, a highly experienced Lyme literate doctor, found that multiple tick bites caused greater disease severity:  https://madisonarealymesupportgroup.com/2019/02/22/why-mainstream-lyme-msids-research-remains-in-the-dark-ages/

Others have found that vaccines have reactivated dormant infections:  https://madisonarealymesupportgroup.com/2016/04/24/gardasil-and-bartonella/

Excerpt:

There is further damning evidence that Gardasil can produce life-threatening reactions in those who have been close to a cat, fleas, or ticks, since many of these animals are infected with Bartonella, Babesia, or Lyme (borrelia). Also, since many MSIDS patients (multi systemic infectious disease syndrome) also struggle with viruses such as Mono or active EBV, a cytokine storm can resultwith mucus being over manufactured in lungs and airways and well as wide-spread inflammation.

Asymptomatic girls after receiving Gardasil activated dormant Bartonella which was confirmed by testing.

https://madisonarealymesupportgroup.com/2017/12/02/scottish-doctor-gives-insight-on-lyme-msids/

Excerpt:

He has started treating Lyme Borreliosis patients 20 years ago in the USA and during the last 5 years in Ireland. He has also successfully treated a number of young women who fell ill after their HPV vaccination, which seems to have stimulated a latent Lyme infection to reactivate.

Here, we clearly see that vaccines caused active infection in previously asymptomatic patients.  It makes complete logical sense that a tick bite would do the same, yet mainstream medicine hasn’t a clue and continues to treat this as a simple disease requiring 21 days of doxycycline.

There are pressing answers needed by doctors and patients yet current research seems hell-bent on focusing on climate change.

More climate data will not help patients or doctors one iota.

Category:

Bartonella, research, Rickettsia, Uncategorized

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Russian Journals Retract More Than 800 Papers After ‘Bombshell’ Investigation

https://www.sciencemag.org/news/2020/01/russian-journals-retract-more-800-papers-after-bombshell-investigation

The Russian Academy of Sciences is trying to improve ethical standards in publishing.  ISTOCK.COM/MORDOLFF

Russian journals retract more than 800 papers after ‘bombshell’ investigation

By Dalmeet Singh Chawla

Academic journals in Russia are retracting more than 800 papers following a probe into unethical publication practices by a commission appointed by the Russian Academy of Sciences (RAS). The moves come in the wake of several other queries suggesting the vast Russian scientific literature is riddled with plagiarism, self-plagiarism, and so-called gift authorship, in which academics become a co-author without having contributed any work. (See link for article)

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**Comment**

I assure you, this is happening in the U.S. as well. In fact, I recall a highly unethical article in the MMWR intended to frighten doctors from using IV antibiotics for Lyme patients:  https://madisonarealymesupportgroup.com/2017/06/21/ilads-rebuttal-to-mmwr-article/

Excerpt:

According to Dorothy Leland of Lymedisease.org, the lead author, CDC’s Christina Nelson, essentially trolled for case studies to support her pre-determined conclusions by contacting the Infectious Disease Association of California, and possibly other states, asking doctors to provide examples of misdiagnosed people with chronic Lyme and/or had adverse effects due to treatment of chronic Lyme.  The fact she could only conjure up 5 caseswhen there are nearly 400,000 new cases of LD each year.

She even dangled a carrot by giving them co-authorship.  https://www.lymedisease.org/touchedbylyme-cdc-ignores-ethics/

So right here, we have a perfect example of people being given co-authorship and all they did was provide biased examples of misdiagnosed people with chronic Lyme and/or had adverse effects due to treatment of chronic Lyme.

This type of biased research is rife with Lyme/MSIDS and must stop.

According to investigative journalist Mary Beth Pfeiffer, research on Lyme/MSIDS is owned by a Cabal:  https://madisonarealymesupportgroup.com/2017/01/13/lyme-science-owned-by-good-ol-boys/

And many of these folks have patents on everything from test kits to vaccines:

https://madisonarealymesupportgroup.com/2019/06/28/who-owns-the-elisa-patents/

ConflictReport

Another glaring issue in the research world is the continuing fixation on the acute phase of the disease with perhaps up to 60% of patients struggle with chronic illness:  https://madisonarealymesupportgroup.com/2019/02/25/medical-stalemate-what-causes-continuing-symptoms-after-lyme-treatment/, as well as the continuing fixation on the moniker of climate change when research has shown ticks are oblivious to weather:  https://madisonarealymesupportgroup.com/2018/11/07/ticks-on-the-move-due-to-migrating-birds-and-photoperiod-not-climate-change/

There are many, many issues that need serious study yet the research world refuses to touch them and continues to do biased work with a preconceived outcome to the demise of extremely sick patients.

 

 

 

 

 

Category:

Activism, research

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Who is Lying to You?

Who is Lying to You?

WHO IS LYING TO YOU? Highlights from “The HighWire”
Top World Health Officials’ Shocking Admissions About Vaccine Safety.

Of course Youtube would censor this extremely important video.  I found it here.  Doctor after doctor expose the problems surrounding vaccinations.

For more: https://madisonarealymesupportgroup.com/2019/08/09/former-merck-scientist-explains-why-he-doesnt-vaccinate-his-children-due-to-lack-of-vaccine-safety-studies/

https://madisonarealymesupportgroup.com/2018/09/08/acip-vote-yes-for-new-vaccine-despite-no-safety-studies-on-cumulative-effect-with-other-vaccines/

https://madisonarealymesupportgroup.com/2019/01/22/bill-gates-former-doctor-says-billionaire-refused-to-vaccinate-his-children/

https://madisonarealymesupportgroup.com/2019/06/13/blast-from-the-past-cdc-vaccine-authors-destroy-evidence-of-vaccine-harm/

https://madisonarealymesupportgroup.com/2018/10/08/vaccine-safety-efficacy-studies-that-are-the-bases-for-marketing-authorizations-are-a-complete-methodological-mess/

https://madisonarealymesupportgroup.com/2019/12/03/fda-admits-vaccines-contaminated-with-seriousviruses-including-cancer/

https://madisonarealymesupportgroup.com/2017/10/15/vaccines-and-retroviruses-a-whistleblower-reveals-what-the-government-is-hiding/

https://madisonarealymesupportgroup.com/2017/09/19/autism-aluminum-adjuvant-link-corroborated/

https://madisonarealymesupportgroup.com/2018/06/15/canadian-data-more-autism-where-vaccine-coverage-is-highest/

Category:

Activism, vaccines

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Martine McCutcheon: Star Diagnosed With Serious Infection – Symptoms of Condition

January 10, 2020

https://www.express.co.uk/life-style/health/1223608/martine-mccutcheon-health-latest-lyme-disease-symptoms-uk-rash-me

Martine McCutcheon health: Star diagnosed with serious infection – symptoms of condition

Martine-McCutcheon-Lyme-disease-and-ME-1223608

Martine McCutcheon has been suffering with her illness (Image: Getty)

By CHANEL GEORGINA
MARTINE MCCUTCHEON, famous for playing EastEnders’ Tiffany Mitchell, revealed how her health struggle made her life a “living hell”. Battling two conditions, the actress – who also starred in Love Actually – fell into a dark depression trying to manage her illnesses.
Martine McCutcheon, 43, was first diagnosed with Chronic Fatigue Syndrome (ME) in 2011, and then was later diagnosed with Lyme disease. ME is a long-term illness that causes an overwhelming feeling of tiredness, and Lyme disease is an infectious bacterial condition passed on from being bitten by an infected tick…. (See link for article)
____________________
This article states England ranks as one of the worst nations in Europe for Lyme disease:  https://www.express.co.uk/news/uk/1124081/lyme-disease-south-east-england-london-kent-essex-sussex-symptoms-Mario-Stanchev.  However, it has nothing to do with the climate as the article contends, but rather to migrating birds and the amount of light ticks need to molt (photo period):  https://madisonarealymesupportgroup.com/2018/11/07/ticks-on-the-move-due-to-migrating-birds-and-photoperiod-not-climate-change/

Category:

Lyme

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Vitamin D Increases Protection Against Infection, New Model Suggests

https://medicalxpress.com/news/2019-12-vitamin-d-infection.html

DECEMBER 31, 2019

Vitamin D increases protection against infection, new model suggests

by Oregon State University

Vitamin D increases protection against infection, new model suggests

Oregon State University researchers have led the development of a new model for studying vitamin D’s role in infection prevention, and tests using the model suggest that vitamin D treatment can dramatically reduce the number of disease-causing bacteria in skin wounds.

In addition to shedding light on potential, the study is important because it established a new way to probe the mechanisms through which D regulates an important antimicrobial peptide in the body.

Findings were published in the Journal of Steroid Biochemistry and Molecular Biology.

Vitamin D, which is fat-soluble and present in very few foods—including the flesh of fatty fish, beef liver, cheese and egg yolks—promotes calcium absorption in the gut and is needed for bone growth. Vitamin D, manufactured by the body when triggered by sunlight, is also important for , neuromuscular function, and reduction of inflammation.

OSU scientist Adrian Gombart and collaborators have been probing the vitamin’s role in combating infection, with past studies involving loading wound dressings and sutures with vitamin D.

The current study examines the bioactive form of vitamin D’s role in promoting the body’s production of the cathelicidin antimicrobial peptide, typically abbreviated to CAMP. A peptide is a compound consisting of two or more amino acids linked in a chain, and CAMP is made by and cells that provide a barrier against infection, such as skin and gut cells.

The gene that codes for CAMP is present in humans and other primates. Other mammals including mice have a similar gene, Camp, but vitamin D does not trigger it.

To study how vitamin D and CAMP work together to help thwart infection, Gombart and his research team developed a line of mice that carry the CAMP gene but not Camp. They bred mice engineered to carry human CAMP to mice with their Camp gene knocked out, resulting in mice with an antimicrobial peptide gene regulated by the bioactive form of vitamin D.

The scientists believe the novel model will be useful as research into vitamin D-induced expression of CAMP progresses, involving diseases caused by microorganisms and also conditions that are “non-pathogenic,” such as .

In this study, researchers showed that the with the human CAMP gene had increased resistance to gut infections, and that staph infections on their skin could be successfully treated with the bioactive form of the vitamin.

“Vitamin D3 regulates the expression of the CAMP, and Staphylococcus aureus is an important human pathogen that causes skin infections,” said Gombart, professor of biochemistry and biophysics in OSU’s College of Science and a principal investigator at the university’s Linus Pauling Institute. “With our mouse model, we showed that treating a skin wound infected with S. aureus with the bioactive form of vitamin D significantly reduced the number of bacteria in the wound.”

The finding, Gombart said, suggests vitamin D can be used to increase protection against infection via increased CAMP levels.

Category:

research, Supplements

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