https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260789/

Published online 2020 May 30. doi: 10.1186/s12941-020-00364-0
PMCID: PMC7260789
PMID: 32473652

Presence of Borrelia miyamotoi infection in a highly endemic area of Lyme disease

Abstract

A series of cases in the Northeast of the US during 2013–2015 described a new Borrelia species, Borrelia miyamotoi, which is transmitted by the same tick species that transmits Lyme disease and causes a relapsing fever-like illness. The geographic expansion of B. miyamotoi in the US also extends to other Lyme endemic areas such as the Midwestern US. Co-infections with other tick borne diseases (TBD) may contribute to the severity of the disease. On Long Island, NY, 3–5% of ticks are infected by B. miyamotoi, but little is known about the frequency of B. miyamotoi infections in humans in this particular region. The aim of this study was to perform a chart review in all patients diagnosed with B. miyamotoi infection in Stony Brook Medicine (SBM) system to describe the clinical and epidemiological features of B. miyamotoi infection in Suffolk County, NY. In a 5 year time period (2013–2017), a total of 28 cases were positive for either IgG EIA (n = 19) or PCR (n = 9).

All 9 PCR-positive cases (median age: 67; range: 22–90 years) had clinical findings suggestive of acute or relapsing infection.

All these patients were thought to have a TBD, prompting the healthcare provider to order the TBD panel which includes a B. miyamotoi PCR test.

In conclusion, B. miyamotoi infection should be considered in the differential diagnosis for flu-like syndromes during the summer after a deer tick bite and to prevent labeling a case with Lyme disease.

__________________

**Comment**

https://madisonarealymesupportgroup.com/2018/09/04/borrelia-miyamotoi-in-immunocompetent-patient/

Dr. Cameron states:  “Until now, there have been no treatment guidelines for B. miyamotoi and regimes have been empirically based on the treatment for Lyme disease. ‘The antimicrobial susceptibility of B. miyamotoi has not yet been elucidated, due to difficulties with cultivation of B. miyamotoi spirochetes in vitro,’ according to Koetsveld.  http://danielcameronmd.com/best-antibiotics-treat-borrelia-miyamotoi/  The study authors demonstrated that B. miyamotoi is susceptible to doxycycline, azithromycin, and ceftriaxone but resistant to amoxicillin in vitro. The next step would be to show whether these drugs work in patients.”

For more:  https://madisonarealymesupportgroup.com/category/borrelia-miyamotoi-relapsing-fever-group/http://danielcameronmd.com/dont-count-on-a-relapsing-fever-to-diagnose-borrelia-miyamotoi/
“You might assume a patient infected with Borrelia miyamotoi, a relapsing fever spirochete, to present with a relapsing fever. However, your assumption would be wrong 48 out of 50 times, according to a case series published in the Annals of Internal Medicine. [1] The authors found that only 2 out of 50 patients infected with the relapsing spirochete B. miyamotoi actually presented with a relapsing fever. [1]….The individuals exhibited symptoms similar to those found in other tick-borne illnesses.
The majority presented with headaches, myalgias, arthralgias, and malaise/fatigue. ‘More than 50% were suspected of having sepsis, and 24% required hospitalization,’ states Molloy. [1]…..’Serologic testing using the rGlpQ EIA seems insensitive in diagnosing acute BMD infection given that it was positive for IgG or IgM in only 16% of the case patient samples at the time of clinical presentation,’ states Molloy. The rGlpQ was positive after the fact in 86% of the patients during convalescence. [1]….Elevated liver enzyme levels, neutropenia, and thrombocytopenia were common in 75%, 60% and 51% respectively.
‘Borrelia miyamotoi disease may be clinically similar to or be confused with human anaplasmosis,’ according to Molloy….B. miyamotoi has emerged as a leading cause of hard tick-transmitted infections but lacks a clear diagnostic criteria. According to Molloy, “Infection with B. miyamotoi is the fifth recognized Ixodes-transmitted infection in the northeastern United States and should be part of the differential diagnosis of febrile patientsfrom areas where deer tick–transmitted infections are endemic.’”

https://www.lymedisease.org/next-online-meeting-of-tbd-working-group-is-july-8/

Next online meeting of TBD Working Group is July 8

 “IF the CDC posts any Lyme treatment guidelines, that they include guidelines on persistent Lyme disease.

The recommendation regarding persistent Lyme disease was moved and seconded. Then, for unstated reasons, five panel members abstained from voting. The vote was announced as five abstaining, five yes votes and three no votes.”

tbdwg vote on persistent lyme

https://madisonarealymesupportgroup.com/2020/05/11/persistent-lyme-a-sticking-point-for-tbd-working-group/

Excerpt:

Remarks made after the vote made it clear that the abstainers felt they had defeated the measure, because “yes” votes didn’t comprise a majority of panel members. But, oops, guess what? Abstentions don’t count one way or the other. So, the recommendation passed, 5-3.

As that reality sank in, pandemonium broke out. Panelist Scott Commins stoutly announced that he wanted to change his abstaining vote to “no.” He was told that Robert’s Rules of Order don’t allow you to change your vote after the fact.

Things then got very bizarre very fast, with many people talking at once. Some wanted to vote on the original question again. Others didn’t. Some wanted to re-open discussion, others didn’t. It was confusing to the listener at home.

However, the five abstainers sure gave the impression they had been trying to game the system—to gain a “no” vote without having to publicly own up to it. When that ploy didn’t work, they scrambled to recoup their original objective— to deep-six the proposal regarding persistent Lyme disease.

The upcoming meeting should be entertaining.

Unfortunately, lives are at stake. We really don’t want entertainment – we need answers.

 

https://www.thegatewaypundit.com/2020/06/association-american-physicians-surgeons-sues-fda-irrational-interference-access-life-saving-hydroxychloroquine/

Association of American Physicians and Surgeons Sues FDA for “Irrational” Interference of Access to Life-Saving Hydroxychloroquine

The Association of American Physicians and Surgeons (https://aapsonline.org) filed a lawsuit against Department of Health and Human Services and the FDA for “irrational interference” by the FDA with timely access to hydroxychloroquine.

Never in history have we seen such a determined effort by the scientific community and pharmaceutical industry to downplay and lie about the use of a successful drug to treat a deadly disease.

Hydroxychloroquine is the first choice in a study of 6,000 doctors treating the coronavirus.  In the field and in independent testing hydroxychloroquine displayed amazing results in treating the COVID-19 virus.

But there was great pushback against hydroxychloroquine for two reasons. The first reason was because it was safe and very inexpensive. The second reason is because Donald Trump promoted its use. (See link for article)

___________________

**Comment**

Just today, the FDA just doesn’t care what works in the clinical setting and gives a big fat NO to HCQ:  https://www.medpagetoday.com/infectiousdisease/covid19/87066?xid=NL_breakingnewsalert_2020-06-

The purpose of recent HCQ paper in the Lancet was to create uncertainty and skepticism in the drug’s ability to treat COVID-19 because the authors have financial ties to big Pharma.  https://madisonarealymesupportgroup.com/2020/06/06/fraudulent-hcq-covid-19-study-in-lancet-exposed/

They, along with authorities who also have financial conflicts, want to promote more expensive pharmaceutical options – including Remdesivir. HCQ has shown success in studies around the world, is cheap, has been used safely for decades, and has clinical benefit to certain patients early in the disease process:  https://madisonarealymesupportgroup.com/2020/06/01/rebuttal-on-huge-hcq-study-in-lancet/

Science has been hijacked as well:  https://madisonarealymesupportgroup.com/2020/06/06/fraudulent-hcq-covid-19-study-in-lancet-exposed/

https://madisonarealymesupportgroup.com/2020/06/12/former-french-health-minister-blows-whistle-criminal-pressure-from-bigpharma-on-publications-means-theres-no-longer-any-real-science/

Excerpt:  

The Lancet’s boss, Horton, said:

“Now we are not going to be able to, basically, if this continues, publish any more clinical research data, because the pharmaceutical companies are so financially powerful today and are able to use such methodologies, as to have us accept papers which are apparently methodologically perfect but which, in reality, manage to conclude what they want to conclude…

Until the Bayh-Dole Act is repealed, our own government, which is entrusted with public health, is allowed to own patents competing with the private sector. They then are entrusted to set public policy including treatment guidelines despite this conflict of interest.  https://madisonarealymesupportgroup.com/2020/05/20/cdc-crimes-possible-sherman-provisions-clayton-acts-violated/ This link shows that our own government, regarding COVID-19, violated the Sherman Act by taking U.S. tax dollars to China to do coronavirus research as well as violated the Clayton Act by entering into trade among states.

Here’s the successful HCQ studies the FDA must not be looking at:  https://madisonarealymesupportgroup.com/2020/06/09/hcq-breakthrough-icmr-finds-its-effective-in-preventing-coronavirus-expands-its-use/

https://madisonarealymesupportgroup.com/2020/05/22/new-study-hcq-zinc-greatly-reduces-covid-19-health-risk/

https://madisonarealymesupportgroup.com/2020/05/11/podcast-evidence-supporting-hcq-azithromycin-for-covid-19/

https://madisonarealymesupportgroup.com/2020/04/24/dr-oz-interviews-dr-didier-raoult-on-hydroxychloroquine-study-for-covid-19/

Regarding effective COVID treatments, the CDC has stonewalled another one as well:  https://madisonarealymesupportgroup.com/2020/06/02/successful-covid-19-critical-care-stonewalled-by-cdc/

According to Kory, the FLCCCs MATH+ protocol has been delivered to the White House on four occasions, yet no interest has been shown. Worse, he says they continue to be stonewalled by the U.S. Centers for Disease Control and the National Institute for Health. Why?

Isn’t saving lives, right now, and by any means possible, more important than pushing for a vaccine? If the MATH+ protocol works with near-100% effectiveness, a vaccine may not even be necessary. The MATH+ protocol gets its name from:

Intravenous MethylprednisoloneHigh-dose intravenous Ascorbic acid

Plus optional treatments Thiamine, zinc and vitamin D

Full dose low molecular weight Heparin

You quickly come to the conclusion that there are people who would rather see patients remain sick.

https://www.journalnow.com/news/local/bourbon-virus-new-tick-borne-disease-may-be-in-north-carolina/article_

Bourbon virus? New tick-borne disease may be in North Carolina

https://thehighwire.com/fluoride-on-trial-cdcs-greatest-public-health-achievement-exposed/

Fluoride on Trial: CDC’s ‘Greatest Public Health Achievement’ Exposed

By Jefferey Jaxen

As Coronavirus fears have gripped the world for months, a litany of scientific scandals, inconsistencies and frauds have drawn the public’s attention to an underbelly of our agenda-driven scientific community.

From the flimsy Imperial Model that kicked off lockdowns in the U.S. and UK, to the Lancet’s hydroxychloroquine study retraction, corporate science is being scrutinized like never before, and with excellent reason.

And while the medical establishment community has experienced one egg on its face after another, and corporate media grasps at straws to report on whatever can amp up ratings and fear to “11,” you probably missed a BIG story.

On June 8, a lawsuit demanding that the Environmental Protection Agency (EPA) ban fluoride chemicals from U.S. water supplies went to trial in the U.S. District Court for the Northern District of California in San Francisco.

The case, Food & Water Watch, Inc. et al v. EPA, is the first in which plaintiffs have succeeded in going to trial after EPA denied their petition for regulating the substance under the Toxic Substances Control Act section 21.

Three groups brought the case against the EPA to court: Fluoride Action Network, Food and Water Watch, and Moms Against Fluoridation. The plaintiffs are requesting a prohibition on fluoride in U.S. water supplies under the Toxic Substances Control Act of 1976, which warrants the EPA to stop the usage of a chemical to protect public safety.

The U.S. Centers for Disease Control and Prevention (CDC) considers community water fluoridation one of the ten greatest public health achievements of the 20th century.  A self-proclaimed achievement, blindly backed by the medical community, lacking long-term scientific studies to prove it’s actually true.  

Those who’ve challenged this view in the past, whether from academia or the general public, have been quickly labeled quacks, conspiracy theorists and other PR industry terms. But gradually, over time and experience, attempts to distract away from inconvenient truths surrounding the fluoridation of public drinking water supply have failed.

A landmark shift in the dogmatic science of water fluoridation occurred in 2019. The highly respected Journal of the American Medical Association (JAMA) Pediatrics published a study: Association Between Maternal Fluoride Exposure During Pregnancy and IQ Scores in Offspring in Canada. 

Funded by the Canadian government and the U.S. National Institute of Environmental Health Science, the study examined the association between fluoride exposure during pregnancy and the IQ scores of the children at ages 3 and 4 years of age. It concluded

“…maternal exposure to higher levels of fluoride during pregnancy was associated with lower IQ scores in children aged 3 to 4 years. These findings indicate the possible need to reduce fluoride intake during pregnancy.”

Plaintiffs in the current EPA lawsuit called expert witness Dr. Bruce Lanphear, a professor of health sciences at Simon Fraser University in Canada, and author of the JAMA Pediatrics IQ study. He testified that higher exposure to fluoride during pregnancy “was associated with diminished IQ scores in children at 3 to 4 years of age.”

Lanphear testified that he was not being compensated for his work in the legal case, but that he believed it was part of his public service duty to participate in it.

“We’ve allowed children with rapidly growing brains to be exposed to toxins,” Lanphear told the court.

JAMA Pediatrics Editor-In-Chief Dimitri Christakis stated during an episode of Editors Summary podcast, “For me, before there were ‘anti-vaxers’ there were sort of ‘anti-fluoriders.‘”

He shared that while he was going through residency, the traditional teaching he received was that “fluoride is completely safe. All these people that are trying to take it out of the water are nuts.” He commented about the recent study’s findings saying they were “sizable” and “on par’ with the IQ drops seen in children exposed to lead.  When Christakis was asked what he would recommend as a pediatrician if a pregnant mother came into his office he replied “I would advise them to drink bottled water.”

Studies on fluoride’s effect on the brain include 65 IQ studies, 156 human studies, 286 animal studies, 36 cell studies and 40 review studies. Those who have questioned water fluoridation are regularly labelled anti-science, accused of ‘cherry-picking’ scientific studies to fit a narrative. A comparison below of agencies who oversee regulation and promotion of water fluoridation vs the grassroots organization Fluoride Action Network paints a different picture.

The trial has seen three days of testimony and is slated to restart Monday. Plaintiffs’ witnesses include four decorated and well-respected academics who have been used in the past by the EPA as go-to experts on the neurotoxicity of lead and mercury.

In the trial’s opening statements, plaintiffs lawyer Michael Connett said it ”will be undisputed in this case that babies who are bottle-fed with fluoridated water receive the highest doses of fluoride of any age group.” At the time of “their greatest vulnerability, we are exposing infants, often from the poorest, most disadvantaged communities, to a very high burden of fluoride,” Connett said.

Day two saw five hours of testimony by Philippe Grandjean, MD, ScD, an epidemiologist at the Harvard School of Public Health and head of the Environmental Medicine Research Unit at the University of Southern Denmark. Dr. Grandjean found “no reasonable doubt that developmental neurotoxicity” was “a serious human health risk associated with elevated fluoride exposure.” That exposure, he said, is “occurring at the levels added to drinking water in fluoridated areas.”

Reporting on the trial, LAW360.com writes:

Dr. Kris Thayer, director of the EPA’s Chemical and Pollutant Assessment Division, testified by video Wednesday that while there are limitations to the data collected in studies of the impact of fluoride exposure on animals, the animal studies support the conclusion that fluoride causes neurotoxic effects in humans. Thayer, who previously worked at the National Toxicology Program, said the human brain is more vulnerable to toxic agents at infancy than adulthood because infants don’t have fully developed blood-brain barriers.”

The court also watched the deposition video from Casey Hannan, director of the CDC’s Oral Health Division who confirmed that his agency agreed with the National Research Council’s 2006 findings that fluoride “interfere with the function of the brain and body by direct and indirect means…”

Another key piece of testimony came from Kathleen M. Thiessen, Ph.D., who was pivotal in creating the landmark 2006 National Research Council’s consensus study report ‘Fluoride in Drinking Water: A Scientific Review of EPA’s Standards‘. Dr. Thiessen admitted that sodium fluoride, the same version the EPA regulated as a pesticide, is being added to water supplies. She also conceded that the EPA has failed to assess the risk of fluoridation based on neurotoxicity.

From glyphosate to opioid painkillers. From talc to Risperdal. From vaccines to masks. Science is on trial in America and the public is taking notice. The outcome of the current fluoride trial has sweeping implications socially, culturally and scientifically too vast to cover in one article.

The trial is currently scheduled out through June 19. Follow The Fluoride Action Network’s Twitter page for live tweets during the trial proceedings. To listen or watch directly, use the links outlined by Fluoride Alert HERE.