https://www.womensinternational.com/how-do-hormones-affect-the-heart/

How Do Hormones Affect the Heart?

Written by Michelle Violi, PharmD – Women’s International Pharmacy

“How does hormone supplementation affect the heart?” This is a question that our pharmacists hear regularly. Much like the poor, maligned egg in the cardio-healthy diet, hormones have fallen in and out of favor with regard to their effect on the cardiovascular system over the years.

Although a number of studies examine hormonal effects on the cardiovascular system, these studies rarely distinguish between bioidentical and synthetic hormones. However, one study by Dr. Ferdinand Roefsena, Rebecca J. Yang, and Dr. Johannes Veldhuis looked specifically at the bioidentical hormones, estradiol, and progesterone, publishing their results in the Journal of the Endocrine Society. Let’s see what they found!

How Was the Study Designed?

Forty healthy postmenopausal women, ages 50-80, participated in the study. The women were divided into four treatment groups:

  1. Bioidentical estradiol (injection) and bioidentical progesterone (by mouth)
  2. Bioidentical estradiol (injection) and no bioidentical progesterone
  3. Bioidentical progesterone (by mouth) and no bioidentical estradiol
  4. No bioidentical estradiol and no bioidentical progesterone

After 23 days of using these therapies, the women’s blood was drawn and the researchers measured various markers.

What Did the Study Look At?

Because the study was only 23 days long, Dr. Roefsena et al. were unable to evaluate primary endpoints,such as heart attacks or strokes. Instead, they looked at various markers in the blood that have been associated with physical outcomes such as heart disease, stroke, and diabetes. The researchers looked at many significant markers, including:

  1. Total cholesterol
  2. Low-density lipoprotein cholesterol (LDL-C) (referred to as “bad” cholesterol by the American Heart Association)
  3. High-density lipoprotein cholesterol (HDL-C) (referred to as “good” cholesterol by the American Heart Association)
  4. Apolipoprotein B (Apo B)
  5. High sensitivity C-reactive protein (hsCRP)
  6. Adiponectin

With the exception of HDL-C and adiponectin, for which higher levels appear beneficial, decreased levels of the other markers listed above are generally considered favorable, according to the American Heart Association.

What Did the Study Find?

When compared to women who weren’t using any hormone therapies:

  1. Women who used bioidentical estradiol alone had lower levels of total cholesterol, LDL-C, and Apo B. They also had higher levels of HDL-C, which are considered beneficial differences. The researchers had expected this result, based on previous studies as described in the article The Bioidentical Hormone Debate: Are Bioidentical Hormones (Estradiol, Estriol, and Progesterone) Safer or More Efficacious than Commonly Used Synthetic Versions in Hormone Replacement Therapy? by Dr. Kent Holtorf.
  2. Women who used bioidentical progesterone alone had decreased adiponectin, but they were still well within the average reference range (below which would indicate risk).
  3. Women who used bioidentical estradiol and bioidentical progesterone together had lower levels of total cholesterol, LDL-C, Apo B, and HDL-C. While the reduced HDL-C levels are not considered beneficial, other studies, as discussed in Dr. Holtorf’s article, indicate that when synthetic progestins are used instead of bioidentical progesterone, the cholesterol and LDL-C-lowering effect of bioidentical estradiol is also blocked. Bioidentical progesterone did not block this effect!
  4. hsCRP levels were higher in women using bioidentical estradiol and bioidentical progesterone, but still well below the value above which indicates increased risk.

In Summary:

As the researchers expected, the women using bioidentical estradiol exhibited improved cholesterol levels (including decreased LDL-C and increased HDL-C). Even though the bioidentical progesterone was associated with reduced HDL-C levels, it allowed the positive effects of bioidentical estradiol on the other cholesterol levels to remain. Synthetic progestins have been seen to reduce the positive effects of bioidentical estradiol on cholesterol levels, as evidenced by the studies discussed in Holtorf’s article. These findings suggest that bioidentical hormones may be preferable to synthetic.

This study is not without its flaws, such as its short length and small group size. Its short length made it necessary to evaluate markers rather than primary endpoints, and the data was further limited by comparing the groups to each rather than evaluating the differences between the beginning and ending measurements. The patients in the bioidentical estradiol groups were treated with injectable bioidentical estradiol—a form which is rarely used in clinical practice—and used two doses ten days apart as opposed to the usual two- to four-week intervals.

Despite this study’s shortcomings, when we combine its results with information obtained in other studies, we see that bioidentical progesterone doesn’t appear to interfere with the positive effects estrogen has on cholesterol levels. By contrast, other studies have suggested that synthetic progestins do negate these effects. And this makes perfect sense! Why would we assume that a molecule that is similar, but not identical to what the body makes, should have the same effect in the body as a molecule that is identical to what the body makes?

Due to our differences as individuals, no study is perfect. Therefore, the question of whether hormones are good for your heart may never be answered definitively because the answer may differ from person to person. Through studies like that by Dr. Roefsena et al. and others, however, one thing is becoming clear: the difference between bioidentical and synthetic hormones may prove a significant factor in whether hormones are beneficial to the heart.

Additional Resources:

Women’s International Pharmacy has several other articles focused on how hormones affect heart health. Check them out at our Heart Health Resources page!

© 2019 Women’s International Pharmacy

Reviewed by Carol Petersen, RPh, CNP; Women’s International Pharmacy

https://articles.mercola.com/sites/articles/archive/2019/03/20/measles-vaccine-mandatory.aspx?

Measles Propaganda Can Have Dire Public Health Ramifications

Written by Dr. Joseph Mercola
measles vaccine mandatory

STORY AT-A-GLANCE

  • The annual numbers of reported measles cases since 2000 have ranged from a low of 37 in 2004 to a high of 667 in 2014. By March 7, 2019, a total of 228 measles cases had been reported across the U.S.
  • The last recorded measles-associated death in the U.S. occurred in 2015. Before the measles vaccine was developed, the annual death toll from reported measles cases in the U.S. was between 450 and 500
  • In 2016, 20,360 children aged 1 to 19 died. Motor vehicle crashes, firearm-related injuries, cancer, suffocation, drowning, drug overdoses, heart disease and chronic respiratory disease are the major causes of child deaths
  • Recent research shows that when measles infection is delayed, negative outcomes are 4.5 times worse than would be expected in a prevaccine era in which the average age at infection would have been lower
  • A March 5, 2019, U.S. Senate hearing on measles outbreaks and vaccine exemptions centered around the testimony of five witnesses in favor of vaccine mandates. Hundreds of people, a majority mothers of vaccine injured children, remained unheard, and Robert F. Kennedy Jr. was prevented from speaking on the grounds that the hearing was full

The following referenced information contains opinion and perspective on a health topic related to vaccine science, policy, law or ethics that is being discussed in public forums, including in medical, law and other professional journals; newspapers, magazines and other print; broadcast and online media outlets; state legislatures and the U.S. Congress.

Readers are encouraged to go to the websites of the U.S. Department of Health and Human Services (DHHS) for the perspective of federal agencies responsible for vaccine research, development, regulation and policymaking, including the U.S. Centers for Disease Control (CDC) for information on vaccine policymaking; to the U.S. Food and Drug Administration (FDA) for information on regulating vaccines for safety and effectiveness; and to National Institutes of Health’s National Institute of Allergy and Infectious Diseases (NIAID) for information on research and the development of new vaccines.

The World Health Organization has stated that “vaccine hesitancy” is one of the top 10 global public health threats.

Mandatory use of the first vaccine — the smallpox vaccine — became common in the 19th century because that infection had a mortality rate of 30 percent.1 Measles is not and was never as deadly as smallpox. In 1962, a year before the measles vaccine was licensed in the U.S., the measles death rate was reported to be 1 in 1,000 cases.2

However, that 20th century death rate has been challenged by Physicians for Informed Consent arguing that the case fatality figures are based on reported cases and most cases of measles are benign and go unreported.3

Recovery from measles confers lifelong naturally acquired immunity. There is evidence that whatever immunity the measles vaccine provides can wane over time and wear off completely within a decade4 or two.5,6

The answer, we’re told, is booster shots, and making sure every single individual is vaccinated in order to ensure “herd immunity” — a concept that historically applies to naturally-acquired immunity following the recovery from the disease.

Measles infection in developed countries like the U.S. very rarely involves complications that lead to injury or death. If you’re over 50, you might recall a time when measles was a common childhood illness, and most children experienced it and were immune by age 15.7

Parents were not extremely fearful of measles before the vaccine was widely used because, like chickenpox, it was accepted as a childhood rite of passage and complications were rare.

However, measles does have more serious complications for older children and adults, which is why parents in the past wanted their children to get the disease when they were young. Authors of a recent study8 in The Lancet Infectious Diseases reported that when measles infection is delayed, negative outcomes are 4.5 times worse “than would be expected in a prevaccine era in which the average age at infection would have been lower.”

Measles Statistics

According to U.S. Centers for Disease Control and Prevention (CDC) data9 published in 2018, the annual number of reported measles cases since 2000 has ranged from a low of 37 in 2004 to a high of 667 in 2014. As of March 7, 2019, a total of 228 measles cases have been reported across the U.S.10

You can see a graph of the exact number of measles cases for each year going back to 2010 on the CDC’s website.11 The National Vaccine Information Center (NVIC) also has a page detailing the history of measles in the U.S. and other countries with accompanying statistics and references.12

According to the CDC, the last recorded measles-associated death in the U.S. occurred in 2015.13 But even before the measles vaccine was introduced and given to children in the early 1960s, the annual death toll from measles in the U.S. was between 450 and 500,14 and never approached the high death rate of smallpox, which was a far more deadly disease, and which prompted calls for states to pass mandatory smallpox vaccination laws for children.15

While any death, for any reason, is tragic, it is reasonable to ask whether it makes sense to mandate that children receive vaccines for diseases with low mortality rates when there are many other causes of death that are not only easier to prevent but would save far more lives.

According to a special report16,17 on child mortality published 2018 in The New England Journal of Medicine, 20,360 children aged 1 to 19 died in 2016; it goes on to list the top 10 causes of death in this age group.

Twenty percent of deaths (4,074 children) were caused by motor vehicle crashes, which came in at No. 1, followed by firearm-related injuries at 15 percent (3,143 deaths). In terms of disease, cancer was the primary cause of death (1,853 deaths), followed by suffocation (1,430 deaths) and drowning (995 deaths). A total of 982 children died from drug overdoses. Heart disease killed 599 children and chronic lower respiratory disease took the lives of 274.

Where is the evidence that measles is a catastrophic public health concern comparable to smallpox that warrants forcing all children to get vaccinated or be barred from getting a school education?

Senators Paid by Big Pharma Lead Fight for Mandatory Vaccinations

The U.S. Senate Committee on Health, Education, Labor and Pensions held a hearing March 5, 2019 titled “Vaccines Save Lives: What Is Driving Preventable Disease Outbreaks?” 18 The entire hearing centered around the testimony of five witnesses, all of whom were in favor of vaccines.

Meanwhile, more than 500 people, a majority of them mothers of vaccine-injured children, remained unheard in a crowded hallway or overflow rooms, unable to enter the small hearing room.19 According to The Washington Post, Sen. Rand Paul, R-Ky., was the only senator or witness who made a statement questioning vaccine mandates and the threat they pose to autonomy and liberty.20

It’s worth noting that two of the most impassioned senators advocating for mandatory vaccinationsand the elimination of vaccine exemptions, Sens. Bill Cassidy, R-La., and Bob Casey, D-Pa., have also received the largest payments from the drug industry.21 Cassidy received $156,000 from the pharmaceutical industry in 2018, and Casey received $532,859 that year.

Fourteen other Republicans and 12 Democrats also received tens of thousands of dollars apiece from Big Pharma last year. For a complete listing of each member and the exact amount, see Matt Novak’s February 26, 2019, article in Gizmodo.22 Many other members of Congress have received hundreds of thousands of dollars from Big Pharma.23

How can we expect impartiality from lawmakers advocating that everyone should be forced to buy and use vaccines when so many members of Congress have financial conflicts of interest with Big Pharma?

Ironically, while defending the absolute safety of vaccines, Casey and Cassidy are cosponsors of the Vaccine Access Improvement Act (S.3253), introduced in 2018-2018.

This legislation aimed to streamline the taxation for new vaccines eligible for coverage under the federal Vaccine Injury Compensation Program (VICP), which was created by Congress in the 1986 National Childhood Vaccine Injury and expanded under the 21st Century Cures Act enacted in 2016. Cosponsor senator Johnny Isakson, R-Ga., commented on the bill in July 2018:24

“The Vaccine Access Improvement Act offers a commonsense solution to get vaccines to patients more quickly, helping to protect Americans against life-threatening diseases while ensuring that the small number of patients who experience side effects get the care they need.”

The Acts passed by Congress in 1986 and 2016, as well as the Vaccine Access Improvement Act (which died in committee in July 2018),25 acknowledge that damage occurs from FDA licensed and CDC recommended vaccines and that injured children and adults should receive financial aid.

So why were no individuals who have been personally affected by vaccine injuries and deaths allowed to speak at the hearing?

Healthy Eighteen-Year-Old Complains About Mother’s Decision to Not Vaccinate Him

One of the five witnesses was 18-year-old Ethan Lindenberger, whose mother made an informed decision and did not vaccinate him as a child. After doing his own online research, when he turned 18 he made the choice to get vaccinated. In his testimony, a transcript26 of which can be found on the U.S. Senate website, he talks about his mother’s views, saying:

“These beliefs were met with strong criticism, and over the course of my life seeds of doubt were planted and questions arose because of the backlash my mother received when sharing her views on vaccines. These questions and doubts were minor and never led to a serious realization of how misinformed my mother was.”

Repeating identical talking points offered by all of the invited witnesses and all but one senator on the committee, Ethan also stated confidently, “In its essence, there is no debate. Vaccinations are proven to be a medical miracle, stopping the spread of numerous diseases and therefore saving countless lives.”

“There is no debate?” Typically, only talking heads paid by industry take a denialist position like that. A rationally thinking person who has taken the time to look at all of the evidence quickly realizes that

the debate is far from over and vaccine science is nowhere near settled.

House Hearing on Measles Outbreak

The week before the senate’s hearing on vaccines, the U.S. House Energy and Commerce Oversight and Investigations Subcommittee held a hearing on the measles outbreak and response efforts.27 This hearing can be viewed in its entirety on C-SPAN’s website.28

As expected, the witnesses and members of the committee denied there are serious vaccine risks — or if there are, they are almost nonexistent — and pointed the finger at parents with unvaccinated children attending school as the reason for measles outbreaks.

However, according to the CDC, over 94 percent of kindergarten children nationwide have received two doses of measles-containing MMR vaccine and only about 2 percent of children attend school with vaccine exemptions.29

The herd immunity threshold for vaccine-acquired artificial immunity is thought to be between 80 and 95 percent,30 depending on the disease in question. For measles, it’s between 90 and 95 percent. Yet, the high vaccination rate in the U.S. isn’t enough to thwart outbreaks, and evidence suggest they would probably continue to occur even if vaccine coverage was at 100 percent.

Measles Outbreaks Repeatedly Occur in Highly Vaccinated Populations

One of the problems is that measles outbreaks occur even in highly-vaccinated populations.31,32,33,34,35,36A 1994 study37 looking at measles incidence in Cape Town, Africa, indicated that as vaccination rates increased, measles became a disease in populations where the majority of children had been vaccinated. The immunization coverage was 91 percent and vaccine efficacy was estimated to be 79 percent.

According to the authors,

“The epidemiology of measles in Cape Town has thus changed as evinced in this epidemic, with an increase in the number of cases occurring in older, previously vaccinated children. The possible reasons for this include both primary and secondary vaccine failure.”

By the early 1980s, about 95 percent of children entering kindergarten in the U.S. had received a dose of measles-containing vaccine but, in 1989-1990, there were outbreaks of measles among school-age children and college students.

Public health officials responded by recommending a second dose of MMR vaccine for all children. In an article published in Clinical Microbiology Reviews in 1995, researchers stated:38

“Measles, which was targeted for elimination from the United States in 1979, persisted at low incidence until 1989, when an epidemic swept the country. Cases occurred among appropriately vaccinated school-age populations and among unimmunized, inner-city preschool children.

In response to the epidemic, measles immunization recommendations have been modified. To prevent spread among school-age populations, a second dose of MMR vaccine is recommended at 5 to 6 or 11 to 12 years of age.”

Today, measles outbreaks are occurring even in populations that have received two or more doses of measles vaccine, and/or where vaccination rates are above the “herd immunity” threshold. Examples include:

• A 2017 measles outbreak in a highly vaccinated military population in Israel, ranging in age from 19 to 37. The first two patients identified had both received two doses of measles vaccine. Patient zero, a 21-year-old soldier, had documentation of having received three doses.39

• A 2014 study40 conducted in the Zhejiang province in China found that populations that have achieved a measles vaccination rate of 99 percent through mandatory vaccination programs are still experiencing consistent outbreaks far beyond what the World Health Organization expects.

What’s more, 93.6 percent of the 1,015 participants in this study tested seropositive for measles antibodies, which theoretically means they should have been protected against the disease.

Ignoring Vaccine Injuries Is What Causes Mounting Public Distrust

Parents who have experienced the pain of watching a perfectly healthy child decline shortly following vaccination, or who die or are left with disabilities and chronic poor health, are legitimately crying foul for being left out of congressional hearings that called for stricter mandatory vaccination laws, and which criticized parents of unvaccinated children while suggesting vaccine conversations about vaccine risks should be censored on social media.

Public concern about the safety of vaccines is indeed growing. There is a growing distrust of federal health agencies responsible for regulating the safety of vaccines and making vaccine policy, and it’s because Big Pharma and the government are trying to bury the evidence.

Where are the scientifically sound studies comparing the health outcomes of vaccinated and unvaccinated individuals?

When government officials flat-out deny the obvious, the seeds of public mistrust are planted. Today, many of us know someone who has been injured by a vaccine, and more and more people are sharing their stories in an effort to prevent others from having to live through the same pain. It is a reality that simply cannot be denied any longer. To learn more about vaccine injury reports, visit:

  • The NVIC International Memorial for Vaccine Victims,41 where you can search for vaccine injury reports by state and by vaccine or post a vaccine injury report yourself. You can also record your own video reporting a vaccine injury or death and post.
  • Vaccine Injury Stories on Vaxxed.com.42 Here, you can find nearly 7,000 written and recorded stories detailing people’s vaccine injuries, sorted by state or by vaccine. To submit your own story, use this online submission form.43
  • MedAlerts is a searchable database of vaccine injury reports made to the federal Vaccine Adverse Events Reporting System (VAERS) and can be accessed through the website of the National Vaccine Information Center at NVIC.org

__________________

For more:  https://madisonarealymesupportgroup.com/2019/03/15/medical-doctor-of-50-years-current-measles-hysteria-not-based-on-science-but-scientism-a-quasi-religious-faith-in-vaccines/

https://madisonarealymesupportgroup.com/2019/03/06/genetic-sequencing-science-breakthrough-just-proved-that-measles-outbreaks-are-caused-by-the-measles-vaccine/

https://madisonarealymesupportgroup.com/2018/10/27/measles-transmitted-by-the-vaccinated-gov-researchers-confirm/

https://madisonarealymesupportgroup.com/2019/02/01/cnn-forced-to-correct-piece-on-measles/

https://madisonarealymesupportgroup.com/2019/03/15/us-warship-quarantined-at-sea-due-to-virus-outbreak/

https://madisonarealymesupportgroup.com/2019/03/13/vaccine-injury-is-free-as-long-as-we-deny-it/

 

Sorry for the late notice.  Just got this.

What:  Rockford stateline Lyme Support Group meeting tonight (Wed. March 20,2019)
Where:  Mercy Hospital off of Riverside and tollway 9, Rm B3 downstairs next to the cafeteria in the basement

Time:  6pm
Subject:  guest speakers that are talking about Hemp oil and Lyme disease.
___________________

Webinar banner

Vibrant Presents Dr Jill Carnahan for Mold and Mycotoxins
Join us for this highly educational session with Dr Jill Carnahan, a leading expert in mold and mycotoxin illnesses while she discusses the available technology and testing methods for mold and mycotoxin exposure, walks through some case studies, and gives suggestions for pre-test measures and treatment.
Time:  Mar 26, 2019 6:00 PM in Central Time (US and Canada)

 

 

https://www.galaxydx.com/rickettsiosis_rocky_mountain_spotted_fever/

Rocky Mountain Spotted Fever is not the only Rickettsiosis