Archive for the ‘Treatment’ Category

Resolving Persistent Spike Protein Syndrome

https://townsendletter.com/resolving-persistent-spike-protein-syndrome/

Resolving Persistent Spike Protein Syndrome

Thomas E. Levy, MD, JD
Orthomolecular Medicine News Service

6/1/23

Article Excerpts:

As the acute cases of COVID have continued to decline, the prevalence of the Persistent Spike Protein (PSP) syndrome has continued to increase. The spike protein is that part of the COVID pathogen that attaches to ACE2 receptors throughout the body and permits the entry of the entire virus into the newly infected cell. There appear to be no cells, tissues, or organs in the body that are completely spared from this PSP attack once enough of it has been introduced into the body.

The persistent presence of the spike protein has been shown to be secondary to the inability to completely resolve a bout of COVID (chronic COVID or long-haul COVID) as well as the spike protein exposure from mRNA inoculation(s). And as more time has passed, the PSP syndrome following one or more mRNA shots has emerged as the most common reason for PSP, especially following a booster injection. Not surprisingly, the likelihood of developing a PSP syndrome relates directly to the total amount of spike protein exposure, and the amounts delivered by repeated inoculations substantially exceed the amounts that result from incompletely resolved cases of COVID.

The goal of any therapy designed to eliminate a chronic spike protein presence in the body needs to address its presence in the blood, its presence on the many ACE2 binding sites throughout the body, its presence inside the cells, and the mechanisms that allow it to replicate itself and keep it from being eliminated completely in the body. It has been shown that the sickest of PSP patients have intact spike protein circulating in the blood.1 

Multiple autopsy studies have revealed the presence of spike protein throughout the body, without any particular areas being spared.2,3

By itself, the spike protein is also toxic. As all toxins ultimately inflict damage by oxidizing biomolecules needed for normal metabolic function, any effective PSP protocol needs to include significant antioxidative capacity in order to repair damaged (oxidized) biomolecules. Spike protein has been shown to induce inflammation (acute oxidative stress) even without resulting in viral infection.4

Bio-Oxidative Therapies

While any therapy that can eradicate an infectious agent must involve its destruction via enhanced oxidation, the most prominent of these therapies involve the appropriate application of:

  • Vitamin C (multiple modalities)
  • Hydrogen peroxide (multiple modalities)
  • Ozone (multiple modalities)
  • Ultraviolet blood irradiation
  • Hyperbaric oxygen

While still not widely appreciated, these bio-oxidative therapies have been curing acute infectious diseases for very many years now.  (See link for article & references)

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**Comment**

Dr. Levvy states that a good protocol for PSP should include:

  • Ozone autohemotherapy, followed by
  • IV vitamin C (50 to 150 grams daily); or any oral form in the highest doses possible
  • IV or oral hydrocortisone (25 to 50 mg) in the IV or with the first oral dose of vitamin C
  • Ultraviolet blood irradiation if available
  • Hydrogen peroxide nebulization
  • Methylene blue, 25 to 50 mg two or three times daily
  • Proteolytic enzymes (bromelain, NAC, nattokinase)

Benefits of Ozone on Mortality in Patients with COVID-19: A Systematic Review and Meta-analysis

https://petermcculloughmd.substack.com/p/benefits-of-ozone-on-mortality-in?

Benefits of Ozone on Mortality in Patients with COVID-19: A Systematic Review and Meta-analysis

Small Studies Found Benefit Yet Adjunctive Therapy Not Advanced to Large, Multicenter Trials

By Peter A. McCullough, MD, MPH

I attended an integrative medicine meeting recently and one of the speakers said that ozone was one of the most important tools in his practice. While this is a very broad topic with > 4000 papers listed in the National Library of Medicine with the MESH term “ozone therapy,” Hu et al briefly summarized:

“Ozone is a molecule composed of three oxygen atoms and a component of the atmosphere in nature, which has a strong oxidizing action. Ozone has a high-energy, variable molecular structure under normal temperature and is quickly and spontaneously decomposed into O2 and a single oxygen atom (O). It has strong activity in oxidation and a strong bactericidal effect on bacteria and viruses.10,11  Ozone therapy inactivates bacteria by disrupting their cell envelope through oxidation of phospholipids and lipoproteins, inhibits fungi growth, damages the capsid of viruses, and upsets the reproductive cycle by disrupting the virus-to-cell contact with peroxidation.12  Oxygen-ozone therapy causes an increase in the rate of red blood cell glycolysis, causing the stimulation of 2,3-diphosphoglycerate, which leads to an increase in oxygen released to the tissues.13”

Innovative physicians, from many parts of the world trialed ozone in hospitalized patients some of whom had 4-6 weeks in the hospital with acute COVID-19. Shang et al performed a meta-analysis of very small studies…. (See link for article)

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https://pubmed.ncbi.nlm.nih.gov/36513208/

Benefits of ozone on mortality in patients with COVID-19: A systematic review and meta-analysis

Abstract

Background: The Coronavirus disease-2019 (COVID-19) pandemic continues, and the death toll continues to surge. Ozone therapy has long been used in the treatment of a variety of infectious diseases, probably through its antioxidant properties and the supply of oxygen to hypoxic tissues. This systematic review and meta-analysis aimed to determine the efficacy of ozone on mortality in patients with COVID-19.

Methods: A systematic search was made of PubMed, Embase, Cochrane Library, and clinicaltrials.gov, without language restrictions. Prospective controlled trials on treatment of COVID-19 with ozone, compared with placebo or blank, were reviewed. Studies were pooled to risk ratios (RRs) and weighted mean differences (WMDs), with 95% confidence intervals (CIs).

Results: Eight trials (enrolling 371 participants) met the inclusion criteria. Ozone therapy showed significant effects on mortality (RR 0.38, 95% CI 0.17-0.85; P = 0.02), length of hospital stay (WMD -1.63 days, 95% CI -3.05 to -0.22 days; P = 0.02), and polymerase chain reaction (PCR) positivity (RR 0.07, 95% CI 0.01-0.34; P = 0.001).

Conclusions: Ozone therapy significantly reduced mortality, PCR positivity, and length of stay in hospitalized patients with COVID-19. Ozone therapy should be considered for COVID-19 patients.

https://pubmed.ncbi.nlm.nih.gov/33169118/

All patients also were given antiviral agents and three were also treated with steroids.

Remdesivir: What You Should Know

Dr. Vernon Coleman: Remdesivir – What You Must Know

“Please share this article with everyone you know. And please send or show copies of this article to every doctor and nurse you can reach. “

By Dr. Vernon Coleman

Remdesivir is described as a `broad spectrum antiviral drug’. It is a RNA polymerase inhibitor which disrupts the production of vital RNA. It is said to prevent the multiplication of SARS-CoV-2.

Remdesivir was introduced for the treatment of covid-19 patients who were in hospital suffering from covid-19, with or without pneumonia. It is still being widely used. I have been researching and writing about drugs since 1970 and I am appalled at the way that it now appears that in some countries some hospitals and doctors (and even nurses) are now routinely giving remdesivir to patients – particularly elderly patients – who do not have severe signs and/or symptoms of the flu or a flu-like viral infection. You can form your own opinion on whether remdesivir ever has a value by reading the following information.

1. Remdesivir is officially used to treat patients who have symptoms of covid-19 or who have covid-19 according to the discredited PCR test which no one with any functioning brain tissue should use. Anyone who uses a PCR test to diagnose covid-19 is a moron and you can tell them I said that. Please see my two recent articles (on http://www.vernoncoleman.com) entitled `PCR: How the PCR test has killed millions’ and `The PCR test can kill you’. A positive PCR test does NOT prove that you have covid-19, dandruff, chilblains, covid-19 or anything else.

2. Remdesivir seems to be very, very popular with very, very stupid doctors who seem to think it is a panacea for all illnesses. If their Mercedes or BMW breaks down they probably give the car a shot of remdesivir.

3. Remdesivir is given directly into a vein. Doctors who tell you that giving drugs via a vein is an entirely safe procedure are stupid. No medical procedure is entirely safe. Giving drugs by injection into a blood stream requires skill and experience to avoid dangers.

4. The brand name of remdesivir is Veklury. (Brand names always begin with an initial capital but generic names are all lower case.) If you are being given Veklury, you are being given remdesivir.

5. Remdesivir should be prescribed by a doctor and given under a doctor’s supervision. (Nurses may wear stethoscopes round their necks, but they are not doctors.)

6. Remdesivir must be given slowly over a period of between 30 minutes and 120 minutes.

7. Hospital patients are usually given remdesivir once a day for up to 10 days.

8. Patients not in hospital are usually given remdesivir once a day for three days.

9. Patients who are given remdesivir MUST have regular blood tests to check that their livers are functioning properly. If a doctor gives remdesivir without doing regular liver function tests he or she is dangerous and, in my opinion, should have their medical licence revoked.

10. Liver function tests MUST be done before remdesivir is prescribed. Any doctor who does not do liver tests before starting treatment should be sacked and have their medical licence revoked.

11. Severe renal toxicity has been noted in animal studies. (Some doctors claim that animal studies are irrelevant. I agree. But why do them if they are irrelevant?)

12. No one should be given remdesivir if they are allergic to it.

13. Anyone who has ever had liver disease or kidney disease should inform their doctor if he/she suggests prescribing remdesivir.

14. Anyone who is pregnant or breastfeeding should tell their doctor. The UK’s National Institute for Health and Care Excellence (NICE) says that the safety of covid-19 antiviral treatment during pregnancy has NOT been established.

15. Remdesivir may interact, to your disadvantage, with other prescription medicines, with over the counter medicines, with vitamins and with herbal products. Doctors who prescribe remdesivir must ask patients about all the medicines they are taking.

16. Remdesivir has received a number of reviews on drugs.com, and of the reviews listed on 24th August 2024, 19.38% or reviewers had a `positive experience’ but 47% had a `negative experience’.

17. According to the journal `Science’, in October 2020,`The World Health Organisation’s Solidarity Trial showed that remdesivir does not reduce mortality or the time covid-19 patients take to recover.’ And `A second, smaller placebo-controlled study of remdesivir on hospitalised covid-19 patients in China, published online by The Lancet on 29th April 2020, found no statistically significant benefit from the treatment – and the antiviral surprisingly had no impact on levels of the coronavirus’. I find it difficult to see why the FDA, the EU and the UK’s drug regulator all approved remdesivir, though they appear to have done so without worrying too much about the research showing that it was pretty useless.

18. Side effects which may occur when remdesivir is injected include: fast, pounding heartbeats; trouble in breathing; wheezing, shivering, itching, sweating, facial swelling, severe headache, a feeling of being about to pass out. Side effects subsequently may include nausea and abnormal liver function tests.

19. NICE reports that there are twelve drugs with which remdesivir inter-reacts. Any doctor prescribing remdesivir should know of these interactions – which are listed on the NICE website. So, for example, the manufacturers advise that patients avoid taking remdesivir with chlorquine, hydroxychloroquine and phenytoin. I cannot put a link to the NICE website because such links are not allowed. The list of side effects below was NOT taken from the NICE website. (Since it is a public sector body and paid for by taxpayers, you’d think that NICE would be delighted to share information about drug dangers wouldn’t you?)

20. Side effects which can occur in patients taking remdesivir may include:

Back pain
Bleeding
Blistering
Burning
Chest tightness
Chills
Coldness
Cough
Dark coloured urine (a possible sign of liver problems)
Difficulty in swallowing
Discolouration of skin
Fast heartbeat
Feeling of pressure
Fever

Flushing
Headache
Hives and itching
Infection
Inflammation
Light coloured stools (a possible sign of liver problems)
Lumps
Nausea and vomiting
Numbness
Pain
Puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
Redness

Scarring
Seizures
Skin rash
Soreness
Stinging
Stomach pain, continuing
Swelling
Tenderness
Tingling
Trouble breathing
Ulceration
Unusual tiredness or weakness
Yellow eyes or skin (a possible sign of liver problems)

You will be relieved to know that not all patients would be expected to have all of these side effects, though a number of these side effects are classified as `common’.

Please share this article with everyone you know. And please send or show copies of this article to every doctor and nurse you can reach. Send copies to your GP and your local hospital.

Unlike NICE I like to share the information I obtain, and unlike YouTube and the mainstream media I believe that the truth should not be censored and must be shared as widely as possible. I suspect that this article will be suppressed and hidden by Google et al. And I am banned from all media (mainstream and online) so please help share this article.

Copyright Vernon Coleman August 2024

NOTE
My first two books `The Medicine Men’ and `Paper Doctors’ dealt with dishonesty and corruption in medicine. `The Medicine Men’ dealt with the relationship between doctors and the drug industry. `Paper Doctors’ dealt with medical research. Both were published in the 1970s and attracted much praise at the time (though not from the pharmaceutical industry or the medical establishment). You can purchase them both from the bookshop on www.vernoncoleman.com

The Defender just came out with two articles on how ‘huge’ financial incentives led hospitals to tragically use COVID treatments that killed patients, which included remdesivir and ventilators.

For more:

Can’t Afford a Lyme-Literate Doctor, Now What?

https://www.globallymealliance.org/blog/cant-afford-a-lyme-literate-doctor-now-what?

Struggling to afford a Lyme-literate doctor? Explore options like reimbursement, payment plans, and NP/PA care. Learn how to access affordable treatment and free resources for tick-borne diseases.

The best way to be appropriately evaluated and treated for tick-borne disease is to see a Lyme Literate Medical Doctor (LLMD). These practitioners are often trained by others in the Lyme field and specialize in the complexities of diagnosis, testing, and treatment of tick-borne disease. LLMDs can be pricey, however, because many of them don’t accept insurance (for information on why that is, see “Why Isn’t My Lyme Disease Treatment Covered by Insurance?”)

Perhaps you’ve been diagnosed with Lyme by your primary care doctor, but you aren’t feeling better after a short course of antibiotics, so now you’d like to see an LLMD. Maybe you have symptoms and risk factors for tick-borne disease, but your standard tests have come back negative, so you’d like to see an LLMD for a detailed clinical evaluation and specialized testing. Maybe you suspect you have a co-infection, but your primary care is only familiar with Lyme. You’ve done your homework and have found an LLMD in your area, but the price of an appointment is prohibitive.

Now what? There are several options you can explore:

Ask about reimbursement

Before just walking away due to sticker shock, ask the LLMD’s office if they offer a “super-bill” that you can submit to insurance for reimbursement. Though the office does not participate with insurance, you may be able to submit the “super-bill” yourself and get at least partial reimbursement for your out-of-pocket costs. Call your insurance company to learn how to submit a claim yourself and to find out what kind of coverage you can expect for an out-of-network provider (a provider who is not otherwise covered by your insurance network). If a claim is denied, ask your insurance company about the appeal process.

Ask about payment plans

Given the high cost of appointments, some providers may offer payment plans. Call the provider’s office to find out if that is an option.

Look into NPs and PAs

Many busy LLMDs have a Nurse Practitioner (NP) or Physician’s Assistant (PA) working in their practice. These practitioners see patients individually, under the guidance of the LLMD, who oversees the care of all patients in the practice and trains the NP or PA. NPs and PAs can order tests, make clinical evaluations, and write prescriptions. The cost for an appointment with an NP or PA is usually less than the cost for an appointment with the LLMD.

Shop Around

Different LLMDs have different appointment costs. The one in your area may be too expensive, but there could be another one just a little farther afield. Think about how far you’d be willing and able to travel to get good and affordable care. (You can search for an LLMD through GLA’s search engine.)

Advocate With Your Current Doctor

If your primary care doctor or other physician who is covered by insurance is not well-versed in Lyme disease, they may be willing to learn. Some doctors are set in their ways, but others are more open to collaborative care. Try gathering information about Lyme disease to bring and discuss with your doctor and talk together about the complexities of Lyme testing and the importance of a clinical diagnosis. You can do this with treatment protocols, too. (For more, see “How to Be an Advocate with Your Non-Lyme Doctor”.)

Explore Financial Assistance

There are several organizations that offer financial assistance for the high costs of Lyme disease appointments and/or treatment. On the Financial Assistance Resources page, GLA maintains a list of organizations that help with treatment access, reimbursement, and federal and state assistance programs.

Join a Support Group

Lyme disease support groups can offer more than emotional support, which is very important; members may also be able to recommend doctors or financial assistance resources. Groups come in different formats, from formal in-person meetings, to small in-person or remote discussions, to online Facebook groups. To find a support group, check out GLA’s Support Groups page.

Get One-on-One Support

Through the Peer-to-Peer Mentor Program, GLA can connect you with a fellow Lyme disease patient, or a knowledgeable caregiver of one, who can offer you one-on-one support. The mentor may have advice for you on finding or affording an LLMD. This program is free.

***

For more:

DMSO: Its History and Remarkable Properties

https://www.midwesterndoctor.com/p/the-remarkable-history-and-safety?

The Remarkable History and Safety of DMSO

Please share your experiences with DMSO with the readers here!

Note: this article has two primary purposes. First, it is a compilation of all the existing safety and toxicology data on DMSO for anyone planning to utilize it in a clinical setting. Second, it is meant to serve as a place to collect reader’s (often incredible) experiences with DMSO so individuals who are considering using DMSO can have testimonials to juxtapose with the wealth of data I am gradually presenting on DMSO.

My time in the medical field has led me to accept many medical practices are adopted because of politics or economics rather than because existing evidence shows they work. Nonetheless, certain instances of this happening still astound me to this day, particularly the blacklisting of DMSO (dimethyl sulfoxide) as:

  • This simple chemical is incredibly safe and effective and treats a wide range of challenging medical conditions that impact millions that still lack an effective therapy (outside of DMSO).
  • Because of its efficacy, once discovered, it took the country by storm, resulting in millions using it, the scientific community getting behind it and publishing thousands of studies on DMSO, numerous pharmaceutical companies making large investments to bring it market, professional athletes promoting it, numerous governors, congressional representatives and senators (on behalf of both themselves and their constituents) pressuring the FDA to give it a fair chance for decades and state legislatures independently legalizing it because the federal government would not.
  • Many approved pharmaceutical products take advantage of DMSO’s properties to work (e.g., in those products, DMSO is often classified as an inert “vehicle”). Similarly, DMSO is FDA approved for one condition (interstitial cystitis) and is approved for a wide variety of veterinary uses (e.g., the same conditions it treats in humans).
  • Over the past 40 years, more than 10,000 articles on the biological implications and 30,000 articles on the chemistry of DMSO have appeared in the scientific literature—much of which, as I’ve shown here is remarkably compelling and paradigm shifting in healthcare.
  • Yet, despite all of that, DMSO was effectively erased from history. It is now widely seen as an unproven and dangerous therapy, and even within the natural health field, most people do not know it exists.  (See link for article)

https://www.midwesterndoctor.com/p/dmso-could-save-millions-from-brain?

DMSO Could Save Millions From Brain and Spinal Injury

The decades of evidence showing DMSO revolutionizes the care of many “untreatable” circulatory and neurologic conditions.

Story at a Glance:

  • DMSO is a remarkably safe chemical that protects cells from otherwise fatal stressors (e.g., freezing, burning, shockwaves, ischemia). Since the heart, brain, and spinal cord are particularly vulnerable to injury, DMSO can produce miraculous results for those conditions.
  • The usage of DMSO completely transforms the management of strokes (including brain bleeds), heart attacks, and spinal cord injuries. As I will show here, had the FDA not sabotaged DMSO’s adoption, in addition to countless lives being saved, millions could have been protected from a lifetime of disability or paralysis.
  • DMSO has many other remarkable properties. For example, it stabilizes proteins, and thus treats many challenging protein disorders (e.g., amyloidosis and numerous genetic disorders).
  • Many conditions DMSO treats are typically considered to be incurable. In this article, I will focus on DMSO’s remarkable utility for the conditions that respond best to intravenous DMSO (e.g., a variety of circulatory disorders like varicose veins or Raynaud’s) and complex neurological disorders (e.g., Down’s Syndrome, Developmental Delay, ALS, Alzheimer’s, Parkinson’s), along with how to administer IV DMSO and DMSO stroke protocols.

If I were stranded on a desert island or knew the world was ending and I could only bring a few therapies with me, one of them, without a doubt, would be DMSO. This is because:

  • It treats a wide range of severe illnesses which are often otherwise incurable and frequently fatal or lead to a lifetime of permanent disability.
  • It effectively treats acute injuries and rehabilitates chronic musculoskeletal disorders (e.g., arthritis). Because of this, it’s one of the best “pain medicines” out there and has allowed many to get their lives back.
  • It has a variety of unique properties that open up a completely different dimension to how medicine can be practiced.
  • It is one of the safest medically active substances in existence.

Remarkably, in the 1960s, this was recognized and DMSO took the nation by storm (e.g., people everywhere were clamoring for it, gas stations would often advertise they sold it, and tens of thousands of research studies were conducted by enthusiastic scientists around the globe). Now however, outside of it being a laboratory chemical or an alternative therapy some people use for joint pain, few are even aware of DMSO’s existence.

This was due to the FDA waging a multi-decade long war against DMSO (despite widespread outcry from Congress and the public), which I believe was arguably the worst thing the FDA has ever done to the country.

Since I am uniquely positioned to present many of the forgotten sides of medicine to the public, I’ve long felt the DMSO story needs to be told. Simultaneously however, since there is a wealth of data on this topic, I wanted to ensure I honored the importance of this subject and accurately present it. For this reason, I’ve spent the last three months reading and arranging thousands of pages of literature. Since there is so much to say on this topic, this series will be broken into a few parts. In the first installment, I will cover the key properties of DMSO and the challenging conditions where it provides the most profound benefits. (See link for article & note there will be another part to it explaining where to get it, dosing, and non-IV protocols)

https://www.midwesterndoctor.com/p/dmso-is-a-miraculous-therapy-for

DMSO is a Miraculous Therapy for Chronic Pain and Musculoskeletal Injuries

The decades of evidence DMSO revolutionizes the practice of medicine

Story at a Glance:

•The standard approach for treating pain and musculoskeletal injuries typically involves giving NSAIDs (e.g., ibuprofen), and in more severe cases, opioids. Unfortunately, these drugs are extremely dangerous (e.g., each one kills tens of thousands of people each year), but nonetheless have remained the standard of care for decades.

•DMSO is a remarkably effective pain-killing agent, in many cases allowing individuals who’d been disabled for years by their pain (e.g., a failed spine surgery or severe arthritis—DMSO’s most popular use) to get their lives back. Furthermore, it can treat many types of pain other therapies do not work on (e.g., complex regional pain syndrome).

•DMSO is a highly effective therapy for healing wounds and creating healthy scars, making it particularly helpful for recovering from surgery.

•DMSO is incredibly effective for healing a wide range of acute and chronic musculoskeletal injuries (e.g., arthritis, headaches, neck and back strains, restless leg syndrome, sprained ankles, trigeminal neuralgia and numerous traumatic injuries). It typically has an 80-90% success rate and often has an instant and dramatic effect. This use was particularly popular with professional athletes, as it allowed many of them to quickly return to the field rather than be out for the rest of the season.

•In this article, I will review the scientific literature that explains how DMSO provides pain relief and healing, the vast body of evidence (comprising of thousands of patients) showing it indeed does, and our preferred DMSO home treatment protocols for pain, arthritis, and musculoskeletal injury (along with the best sources for procuring DMSO).  (See link for article)

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https://www.midwesterndoctor.com/p/how-dmso-treats-incurable-autoimmune

How DMSO Treats “Incurable” Autoimmune and Contractile Disorders

The decades of research that could have prevented an immense amount of human suffering

Article excerpts:

DMSO is a powerful (but safe) anti-inflammatory agent that is often extremely helpful for autoimmune conditions. For example, it’s frequently used to treat asthma, inflammatory bowel diseases (e.g., ulcerative colitis and irritable bowel syndrome), interstitial cystitis (painful bladder syndrome), ITP, lupus, multiple sclerosis, myasthenia gravis, scleroderma, Sjogren’s syndrome, and uveitis.

  • DMSO is also remarkably effective at stabilizing and refolding proteins. This allows it to treat a variety of “untreatable” genetic disorders, and conditions characterized by the abnormal accumulation of misfolded proteins in the body (e.g., amyloidosis) or chronic deposits of excessive contractile collagen (e.g., surgical scars, abdominal adhesions, Dupuytren’s contractures, and Peyronie’s disease). Two of the most dramatic examples of this are scleroderma and fibrodysplasia ossificans progressiva—both “untreatable” conditions where DMSO can provide truly lifesaving benefits.
  • In this article, I will present the wealth of evidence substantiating each of those uses, share my theory on how the unusual antimicrobial properties of DMSO explain some of these benefits, and present DMSO treatment protocols for many of those disorders. Additionally, since many readers requested it, I put together a simplified guide on how to use DMSO orally or topically.

One of DMSO’s remarkable properties is its ability to function as a chemical chaperone and stabilize the three dimensional structure proteins assemble (fold) themselves into. This is important as many complex illnesses (e.g., many genetic disorders) result from misfolded proteins and presently can only be (ineffectively) managed with expensive drugs that aim to normalize the function of the abnormal proteins.

In turn, a few drugs have been developed to refold misfolded proteins, and to my knowledge, the most helpful ones on the market were the ones developed to treat cystic fibrosis (after the Cystic Fibrosis Foundation gave 150 million to bring these medications to market which currently are priced at roughly 300,000.00 a year). However, unlike the existing pharmaceutical chaperones (which are very specific to the misfolded protein), DMSO’s effect is remarkably universal.

Studies have shown DMSO can improve the functionality of the dysfunctional proteins that are seen in genetic disorders like cystic fibrosis,1 hereditary nephrogenic diabetes insipidus,1,2 Machado-Joseph disease,1 Niemann–Pick disease,1,2,3,4,5,6 and a defective protein that causes motor disorders and early death in mice.1 Likewise, it can also treat a variety of complex diseases which result from misfolded proteins damaging surrounding tissue.  (See link for article.  He gives a study in which DMSO was used to treat Alzheimer’s, contractures, Peyronie’s disease, FOP, Scleroderma, & other autoimmune issues like lupus, asthma, IT, MS IBD, MG,& Sjogren’s syndrome) .  Also many patient testimonials are given, including the improvement of Downs Syndrome.)

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**Comment**

Some of the most thorough articles on DMSO yet.  I highly recommend making a pdf of them for your own usage.  This safe treatment has been attacked by the FDA so it may be nearly impossible to get good information on it in the future.

For more: