Archive for the ‘Treatment’ Category

Treatment-Related Complications in Children Hospitalized With Disseminated Lyme Disease

https://academic.oup.com/jpids/article-abstract/6/3/e152/4077162/Treatment-Related-Complications-in-Children?redirectedFrom=fulltext

Treatment-Related Complications in Children Hospitalized With Disseminated Lyme Disease

Journal of the Pediatric Infectious Diseases Society, Volume 6, Issue 3, 1 September 2017, Pages e152–e154,https://doi.org/10.1093/jpids/pix060
Published:  08 August 2017
Abstract
 

We describe here treatment approaches and treatment-related complications in 138 hospitalized children with disseminated Lyme disease. The patients who received parenteral antibiotics had a higher rate of complications than those who received oral therapy (15.4 vs 4.2 per 1000 days of therapy, respectively; P < .05). Oral therapy should be used preferentially if either route is supported by current guidelines.

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**Comment**

It’s no shocker that the children receiving IV antibiotics had more complications than those who used orals; however, IV antibiotics have saved many patients and should not be disregarded as too dangerous.  As gramma used to say, “Don’t throw the baby out with the bathwater.”

More on IV antibiotics: https://madisonarealymesupportgroup.com/2017/07/09/idsa-founder-used-potent-iv-antibiotics-for-chronic-lyme/

https://madisonarealymesupportgroup.com/2017/07/22/how-long-term-iv-antibiotics-saved-a-family/

https://madisonarealymesupportgroup.com/2017/06/26/important-example-of-iv-antibiotics-for-lymemsids/

https://madisonarealymesupportgroup.com/2017/09/02/lyme-disease-and-long-term-antibiotics-contagionlive/

https://madisonarealymesupportgroup.com/2017/09/08/another-lyme-patient-benefits-from-iv-treatment/

 

 

 

IV Ketamine in PTLS

https://www.dovepress.com/effects-of-intravenous-ketamine-in-a-patient-with-post-treatment-lyme–peer-reviewed-article-IMCRJ

Effects of intravenous ketamine in a patient with post-treatment Lyme disease syndrome

Authors Hanna AF, Abraham B, Hanna A, Smith AJ

Published 18 August 2017 Volume 2017:10 Pages 305—308

 

Video abstract presented by Ashraf F Hanna.

Department of Pain Management, Florida Spine Institute, Clearwater, FL, USA

Abstract: Post-treatment Lyme disease syndrome (PTLDS) is a pain disorder for which there remains no gold standard treatment option. Here, we report a case of PTLDS in a female patient whose pain was refractory to treatment options such as radiofrequency ablation, vitamin infusion therapy, opioid analgesics, and other pharmacotherapies. The patient commenced an experimental intravenous ketamine infusion therapy at the Florida Spine Institute (Clearwater, FL, USA) and achieved relief from her chronic pain, an improved quality of life, reduced depression and suicidal ideation, and reduced opioid consumption.

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**Comment**

While I am always on board for relief of patient’s symptoms, PTLS is defined as symptoms remaining after Lyme treatment.  Knowing that this treatment by the mainstream medical establishment is seriously lacking due to the ignorance of borrelia itself (the fact it shape-shifts and persists) as well as the ignorance of coinfection involvement (which necessitates numerous drugs, not just doxycycline) , I question the entire premise of PTLS.  Ketamine may very well be a bandaid covering serious infections that need to be dealt with.

 

Also, it’s important to note what Ketamine is:  http://www.medicalnewstoday.com/articles/302663.php

The drug has hallucinogenic, tranquilizing and dissociative effects, and is one of the recreational drugs used illegally in the club drug scene.

Here are some key points about ketamine:

  • Ketamine was first synthesized in 1962 by Parke-Davis and classified as a controlled substance in the US in 1999.
  • The US military used ketamine as a field anesthetic during the Vietnam War.
  • Ketamine blocks the neurotransmitter glutamate at the receptor, causing a trance-like state and disconnection from one’s environment.
  • Ketamine is the most widely used anesthetic in veterinary medicine.
  • Ketamine is often used as an anesthetic in parts of the world that have limited availability of resuscitation equipment.
  • Because it is odorless, colorless and can render the user unable to move, ketamine has been used as a date rape drug.
  • Ketamine abuse is associated with the use of other “club drugs” including ecstasy.
  • Ketamine is structurally similar to phencyclidine (PCP).
  • Most of the ketamine illegally distributed in the US is diverted or stolen from legitimate sources – particularly veterinary clinics.
  • The complicated, multistep process involved in synthesizing ketamine prevents illicit production of the drug.

A question that begs to be asked is how will Ketamine affect Lyme and other coinfections such as Bartonella which commonly give patients psychiatric symptoms including: hallucinations, anxiety, panic attacks, confusion, memory loss, suicidal ideations, depersonalization, and other cognitive issues similar to side-effects of the drug itself?

Before we simply raise our hands in surrender and take a drug that can put us in a stuporous trance I think we need to continue to do important research as to why patients continue to have debilitating symptoms.

LDA/Columbia 18th Annual Lyme CME Conference: Lyme & Tick-Borne Diseases: What Clinicians Need to Know about an Expanding Epidemic Sept 23-24, 2017

 

LDA/Columbia 18th Annual Lyme CME Conference
Lyme & Tick-Borne Diseases: What Clinicians Need to Know about an Expanding Epidemic

Sept 23-24, 2017
Hilton Penns Landing, Phila., PA. Hotel info

Looking for the real facts on Lyme disease and other tick-borne diseases− what’s happening with coinfections such as Powassan, B. miyamotoi and with Bartonella? What’s new with rickettsial diseases and with tick bite causing meat allergy? Why do Lyme patients often have low blood pressure–how does Lyme affect the heart, breathing, and digestive process when the autonomic nervous system is disrupted? Can Lyme cause optic neuritis? How does inflammation from Lyme affect the brain and how can it be treated? Biofilms and persisters, what are they and are they causing chronic Lyme disease? What are some prevention strategies and have we learned new information from big data?

  Pre-Conference Video, Approx. 3.5 Min

The conference is designed for doctors, nurses and researchers. Those who register for CMEs and CNE’s may receive credit, and the public is also invited to register. An included reception will enable conference attendees to network with the conference faculty.

Thanks to support from the Steven & Alexandra Foundation and IGeneX Labs for this conference.

Click here for Registration and Conference Information:  https://lymediseaseassociation.org/information

 

Questions about Lyme/MSIDS? Ask Dr. Rawls Live Webinar

https://rawlsmd.com/webinars/ask-dr-rawls/?utm_campaign=ask+dr+rawls+webinar+-+sept+2017+-+promo+1+%28HJHHRf%29&utm_medium=email&_ke=YWNhc2htYW5AY2hhcnRlci5uZXQ%3D&utm_source=master+rawlsmd+segment+-+%5Blive+-+2-26-17%5D  Go here to reserve your seat for free

 

No questions about Lyme disease are off the table.

Dr. Rawls is a former Lyme sufferer and author of  Unlocking Lyme. 

 

For more:  https://madisonarealymesupportgroup.com/2017/06/21/spector-rawls-interview-on-lyme-disease/

https://madisonarealymesupportgroup.com/2017/06/03/dr-neil-spector-and-dr-rawls-on-peoples-pharmacy-radio-program/

 

 

 

Dr. Fox: Cat-scratch Fever Warning

http://www.journalnow.com/relishnow/columnists/dr-fox-cat-scratch-fever-warning/article_00ca50bb-119f-5198-b678-7dc4dac77a6d.html

Dr. Fox: Cat-scratch fever warning

  • By Dr. Fox United Feature Syndicate

Dear Dr. Fox: Two years ago I started having short episodes of double vision, numbness on the right side of my face, diminished taste sensation and gait abnormality. For about a week, I had to walk with assistance and could not drive. My primary-care doctor diagnosed me with central origin vertigo and ordered an MRA (to check blood flow to the brain) and an MRI of the brain. The brain showed some spots. I was then referred to a neurologist, who did a lumbar puncture. This confirmed a diagnosis of multiple sclerosis.

The diagnosis was devastating, even though I had no outward signs of the disease. I started taking the oral medication Tecfidera. As time passed, I developed a severe anxiety disorder, and I had obsessive-compulsive tendencies. I had a lot of other psych symptoms that I somehow managed to keep under control. I developed fears of everyday things, such as being afraid to make a pitcher of iced tea, take a shower or do the dishes; if you asked me why I was afraid, I couldn’t tell you. I had turned into a person my husband didn’t recognize.

More symptoms started snowballing as time went on.

Having overcome Lyme disease about 10 years prior, I researched the various diseases and considered that I was infected with Bartonella, also known as cat-scratch fever. When I started reading about it, everything hit home with me.

 

I made an appointment with a vector-borne disease specialist and was tested for Bartonella, cat-scratch fever. The abnormalities in my spinal fluid, brain spots and constant inflammation are most likely caused by the infection.

My doctor and I discussed how I got infected. I do own a cat, and he has bitten and scratched me innocently during play. I recall one occasion when I got a deep bite on the thin skin on the back of my hand, so I figure that these bacteria had almost three years to multiply in my central nervous system. Oh, and it’s not just from cats. It can be contracted from a dog or any animal, plus many insects.

I will be on three different antibiotics daily for several months. Some of the psych and neuro symptoms have resolved, but I still have a way to go. My case may be atypical, but all possibilities have to be considered when it comes to these vector-borne diseases. — C.C., Cumberland, Maryland

Dear C.C.: I’m sure that many readers will sympathize with you and appreciate your call for greater vigilance concerning this bacterial disease transmissible from cats and other animals to humans. Your experience is a warning to all cat owners not to let their cats roam free because they may pick up fleas that have fed on infected cats.

United Feature Syndicate

Write to Dr. Fox c/o Universal Uclick, 1130 Walnut St., Kansas City, MO 64106.

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**Comment**

In my experience this presentation is NOT atypical, in fact, it is quite common at least here in Wisconsin.  And please know – the jury’s out on whether ticks can transmit Bartonella; however, prudence would err on the side of caution and it’s only logical to consider any pathogen in an animal that could be transferred to a tick which then could be transferred to a human.  Logical.

Dr. Ed Breitschwerdt, professor of internal medicine at North Carolina State University, has done the most work with Bartonella noting that nearly half of all cats might carry it and that each animal possibly has its own strain.  That’s a lot of strains.  How can testing keep up with that?  When you read about Bartonella, most articles make it out as a benign pathogen easily dealt with by the immune system.  More and more is coming out about how prevalent and destructive it is.  Certainly for anyone who is immunocompromised, such as Lyme patients, it is a key player.  

Please notice this person’s treatment was 3 antibiotics simultaneously.  That’s a hefty regimen for a benign pathogen that the immune system should be able to handle.  This type of treatment, by the way, is what an experienced ILADS doctor treating tick borne illness would prescribe.  They understand the complexity and interactions of these pathogens since it is rarely just one pathogen.  Since this person had Lyme previously, it might still be a player allowing the Bartonella to do more damage than a person who was not infected.  This is a key issue for health practitioners to get through their heads.  We are rarely infected with just one thing and all the doxycycline in the world is not going to fix this.

The South is really picking up cases, but please note the true infection rates are undoubtedly much, much higher:  https://madisonarealymesupportgroup.com/2016/12/29/cardinal-state-bartonella/

For more on Bartonella:

https://madisonarealymesupportgroup.com/2016/01/03/bartonella-treatment/

https://madisonarealymesupportgroup.com/2016/08/09/a-bartonella-story/

https://madisonarealymesupportgroup.com/2016/11/29/bartonella-seizures/

https://madisonarealymesupportgroup.com/2017/08/02/neurological-and-immunological-dysfunction-in-two-patients-with-bartonella-henselae-bacteremia/

https://madisonarealymesupportgroup.com/2017/07/31/shedding-light-on-bartonella/

https://madisonarealymesupportgroup.com/2017/08/09/bartonella-u-s-clinicians-experience-and-knowledge/

https://madisonarealymesupportgroup.com/2017/05/11/bartonella-henselae-in-children-with-congenital-heart-disease/

https://madisonarealymesupportgroup.com/2017/01/04/endocarditis-consider-bartonella/