We describe here treatment approaches and treatment-related complications in 138 hospitalized children with disseminated Lyme disease. The patients who received parenteral antibiotics had a higher rate of complications than those who received oral therapy (15.4 vs 4.2 per 1000 days of therapy, respectively; P < .05). Oral therapy should be used preferentially if either route is supported by current guidelines.
It’s no shocker that the children receiving IV antibiotics had more complications than those who used orals; however, IV antibiotics have saved many patients and should not be disregarded as too dangerous. As gramma used to say, “Don’t throw the baby out with the bathwater.”