Archive for the ‘Treatment’ Category

How to Overcome a Lyme Treatment Plateau: 4 Steps to Jumpstart Your Recovery

https://rawlsmd.com/health-articles/how-to-overcome-a-lyme-treatment-plateau-4-steps-to-jumpstart-your-recovery

How to Overcome a Lyme Treatment Plateau: 4 Steps to Jumpstart Your Recovery

How to Overcome a Lyme Treatment Plateau: 4 Steps to Jumpstart Your Recovery

by Jenny Lelwica Buttaccio
Posted 1/5/2021

Regardless of whether you’ve been treating chronic Lyme disease for a few months or several years, you’ve probably gone through tough times where you feel like nothing has moved the needle on your symptoms. It can raise all sorts of questions, the big one being, is any of this really helping me, or is it time to give up and move on? Lack of tangible progress is frustrating, but it doesn’t mean all hope for improvement is lost.

Treatment plateaus happen to everyone, and they may look a little bit different from person to person. One person may struggle with pain; for another, it may be lingering neurological symptoms. Whatever the symptoms are that leave you feeling stuck, the question at the forefront of your mind becomes, “Is there any way to move past this?”

By understanding some of the factors that contribute to plateaus, there’s a good chance you can get to the bottom of it, decide on a course of action, and start making progress again. Let’s take a look at four key ways to overcome a frustrating treatment plateau.

#1 Reassess the Five System Disruptors.

Revisiting your current protocol can clue you into areas that might be hindering progress. But if you’ve been treating for months or years, how do you even know where to begin?

First, take a look at the five system disruptors, says Bill Rawls, MD, Medical Director of RawlsMD and Vital Plan. “When you’ve lost momentum, that’s the time to systemically go through the five biggest variables that wreak havoc on the immune system and could affect recovery.”

The chief offenders most likely to impact progress include:

system disruptor-chronic stress

1. Chronic Stress

Constant stress is a biggie when it comes to roadblocks that hinder progress. Unmitigated stress takes its toll on the immune system’s ability to ward off infections. Although you can’t outrun stress, if you’ve recently been experiencing an uptick of it, that’s an area where you can begin to take steps to address it. Activities like vagus nerve stimulation, acupuncture, and deep breathing exercises can help bring on the calm, recalibrate an overworked nervous system, and get some balance back in your life.

system disruptor-poor diet

2. Poor Diet and Food Sensitivities

If you notice gastrointestinal (GI) symptoms like bloating, gas, or inflammation, your diet is the first place to look. The typical modern American diet is full of processed foods, refined carbohydrates, and artificial ingredients that our gastrointestinal systems aren’t built to process, which can cause all sorts of digestive distress. Not to mention, this way of eating is often deficient in the vitamins, minerals, and nutrients your body needs to promote healing.

Food sensitivities linked to the things we eat day in and day out are another factor that may be playing a role in stopping your progress, notes Dr. Rawls. Foods that tend to be the most problematic for people include:

  • Gluten: Found in wheat, rye, barley, and many pre-packaged foods, gluten is a plant protein with the ability to irritate the lining of the gut and cause inflammation.
  • Soy: Soy is a common allergen, and it shows up in a wide range of foods. Edamame, soybean oil, soy lecithin, and soy protein are a few of the soy variations to watch out for.
  • Lectin: Lectins are another type of plant protein found in grains, beans, legumes, tree nuts, and nightshade vegetables like peppers, tomatoes, and eggplant. Lectins may act as an irritant to the gut when they bind to molecules in the cell membranes, leading to irritation, inflammation, and leaky gut syndrome.
  • Mycotoxins: Mycotoxins are mold toxins that, in addition to being found in the environment, are also often found in foods like peanuts, processed meats, mushrooms, and most dairy products. Mycotoxins can induce a host of allergy symptoms and systemic symptoms like fatigue, brain fog, digestive issues, and pain.

Many people experience delayed reactions to the foods they’re sensitive to, so it’s not always easy to pinpoint the cause. If you think your health plateau may be due to food sensitivities, your best bet is to leave those foods out of your diet for a while and see if it yields improvements.

system disruptor-toxins

3. Your Environment

There are all sorts of toxins in the environment that can impair the function of the immune system and all systems of the body, one of the most common ones being mold. For people who have developed sensitivity to mold, mold mycotoxins can cause a barrage of multi-systemic symptoms.

Your body absorbs mycotoxins through the airways as well as the intestinal lining, says Dr. Rawls. “Once mycotoxins are inside of the body, they trigger inflammation and oxidative stress, which further leads to a disruption in immune system functions.”

Like food sensitivities, the effects of mold exposure might not appear for several days. Think back to when your treatment plateau began. Is it possible you’ve come in contact with mold or are dealing with hidden sources of it? If so, take action to try to lower the toxic load as best as you can.

In addition to mold, consider whether there are significant concentrations of other unnatural toxins in your environment and aim to minimize your exposure to those as well. Urban dwellers often have to deal with polluted air, but people living in rural areas can be exposed to high levels of toxic pesticides and herbicides from agriculture.

system disruptor-sedentary

4. Too Little Movement

When you’re feeling ill, exercise is probably the last thing on your mind. However, movement is critical to improve circulation, enhance detoxification, and boost endorphins — all much-needed functions to help you feel better. But don’t feel disheartened if you’re not up to aggressive exercise. Restorative activities like qigong, Pilates, or walking can get the blood flowing while minimizing the risks of a setback or flare-up.

When regular physical activity isn’t practical because of inflamed tissues, infrared sauna can be an adequate substitute. Infrared sauna (or any sauna, for that matter) stimulates blood flow, dilates blood vessels, and flushes debris from tissues. This enhances detoxification and reduces inflammation.

system disruptor-microbes

5. New Microbes

With chronic Lyme disease, there’s always the possibility that coinfections like bartonella, babesia, or mycoplasma may be factoring into the equation and causing symptoms. There’s also the potential for exposure to a new microbe like a virus, or perhaps you’ve had another tick bite. The presence of other stealth pathogens can further hinder the immune system’s ability to ward off infections and might be the hurdle that caused you to stall out on your recovery.

#2 See a Doctor If New Symptoms Pop Up.

medicine, technology and healthcare concept - african american young woman or patient having video chat with doctor on tablet pc computer at home

It’s not uncommon for people with Lyme disease to tough out the day-to-day symptoms. Patients become accustomed to the inability to predict how they’ll feel from one day to the next. But there are times, especially if you’ve undertaken self-treatment, where seeing a doctor is an appropriate step.

“Anytime you have unusual symptoms that are out of the ordinary — you haven’t had them before — you should see a doctor,” says Dr. Rawls. “If you’re having symptoms that are getting worse, you should see a doctor. It could be something other than Lyme, and sometimes, you need to be evaluated.”

Symptoms that should not be ignored include:

  • Chest pain
  • Heart palpitations
  • Shortness of breath
  • Severe or recurring pain somewhere in your body (for example, headaches, abdominal pain, pain with urination)
  • Sudden weight changes
  • Fainting
  • Persistent fevers or one that reaches 103℉ or higher
  • Confusion

These symptoms serve as a guideline; other concerns might arise that aren’t on the list. The bottom line? If something doesn’t feel right, it’s better to have it checked out and get some peace of mind rather than to brush it off.

#3 Change Up Your Herbal Protocol.

three wooden spoons with different colored herb capsules on each

Have you been using herbal therapy for a while and feel like your progress has halted? If so, it might be time to switch things up a little.

“When you’ve used something for a long time, even herbs, I do feel some people build up a tolerance to them,” says Dr. Rawls. “It might not happen to everyone, but it does happen to some people, and we’re not exactly sure why.”

To combat a potential tolerance to herbs, try the following steps to get back on the path to feeling better.

1. Increase Your Current Herbs.

Most herbs have a wide dosing range associated with taking them, meaning some people may need higher doses than others to be effective. If you’re stuck in a rut, but you’ve noticed some gains with your current herbal protocol, try bumping up the dosages — one herb or blend at a time — to see if you experience improvements. Since herbs have a low potential for toxicity, raising the dose is generally considered safe, with the most common side effect being mild GI discomfort.

Additionally, many herbs are warming herbs, which can generate heat in the body and may leave you feeling stimulated. When raising your dosages, Dr. Rawls advises making sure you’re supplementing with immune-modulating herbs like reishi mushroom, sarsaparilla, and ashwagandha as well. These herbs balance the immune system and keep it from kicking into overdrive.

2. Add Different Herbs to The Rotation.

Another question to consider: Could there be other microbes at play contributing to my symptoms? Though the foundational herbs in many protocols have some coverage against coinfections like bartonella, babesia, and mycoplasma, sometimes you need a more targeted approach to suppressing those microbes. To strengthen your defenses against stealth pathogens, Dr. Rawls recommends slowly adding in one new herb at a time. His herbs of choice include:

group of white bidens flowers growing on stems

Bidens

Bidens, specifically Bidens pilosa, is the species that has the most powerful action against malaria and malaria-like microorganisms like babesia. In addition to its antimalarial properties, Bidens pilosa is antibacterial, anti-inflammatory, and neuroprotective.

Suggested dosage: Bidens pilosa is most potent when prepared as an alcohol tincture. The dose may vary depending on the company you buy it from, but tinctures are an excellent way to begin at a low dose of the herb and increase drops as tolerated.

Side effects: There are no known side effects associated with Bidens pilosa, however, some plants can become contaminated with heavy metals. Make sure you purchase the product from a reputable company that takes steps to minimize exposure to heavy metals. Additionally, you should not take this plant if you have diabetes, as it can cause fluctuations in blood glucose or insulin levels.

white Houttuynia flower on green leaves

Houttuynia

Native to India and Nepal, houttuynia is a potent antiviral with activity also against mycoplasma.

Suggested dosage: The dose may vary depending on a company’s preparation.

Side effects: The herb can have a fishy smell but is otherwise well tolerated.

green Crytopleptis leaves and flower

Crytopleptis

Traditionally used to treat malaria in Africa, cryptolepis demonstrates systemic antibacterial properties and antiprotozoal properties. The herb is anti-inflammatory and provides antimicrobial activity against babesia.

Suggested dosage: Cryptolepis is available as a powder, tea, capsule, or tincture, so the dose varies depending on the preparation.

Side effects: It tends to be well-tolerated in most people.

green neem leaves on stem

Neem

Neem is native to India and offers potent antibacterial, antiviral, antifungal, anti-inflammatory, and antioxidant properties. It may contain antimalarial properties against babesia. Also, it has a protective effect on the liver and kidneys.

Suggested dosage: Dosing varies by preparation, so follow the recommendations provided by whatever product use.

Side effects: Most people tolerate the leaf and bark extracts well.

black cumin seeds in wooden spoon

Black Cumin Seed Oil

Native to the Middle East, Europe, and parts of Asia, black cumin seed oil contains antimicrobial, immune-balancing, and anti-inflammatory properties. The herb may be particularly potent against bartonella.

Suggested dosage: The dosing will vary depending on the preparation, so follow the recommendations on the product you choose.

Side effects: The herb is generally well-tolerated, but some mild GI upset has been reported in some people.

Oregano Essential Oil in bliss bottle and dropper

Oregano Essential Oil

As a potent antimicrobial, oregano essential oil has been shown to defend against persistent borrelia infections in patients with chronic Lyme disease symptoms. Oregano oil contains anti-inflammatory and antioxidant qualities as well.

Suggested dosage: Oregano is available as a capsule, liquid, and in liposomal form, and the dose varies depending on the preparation.

Side effects: Oregano oil can cause some GI discomfort, so it’s best to take the herb with food.

3. Know When to Scale Back.

Sometimes, hitting treatment hard for a while can lead to an intensification of symptoms, in which case it might be time to hit the pause button for a bit. Treatment with herbal therapy or other protocols is about finding the “sweet spot,” says Dr. Rawls. It’s a point at which the herbs are potent enough to be effective but not so strong that they cause a harsh Herxheimer reaction and make you miserable.

inside of heat sauna with a bucket of brushed and towels

Detox strategies like infrared sauna, yoga, and rebounding can support your body’s efforts to eliminate debris and toxic substances, so your cells can get the water, nutrients, and oxygen they need for optimal functioning. Plus, there’s no shame in backing off of treatment for a few days or even a couple of weeks until you begin to feel better. Once the intense symptoms subside, slowly ease back into your treatment protocol at lower doses.

#4 Consider Additional Testing.

If you’ve followed the above steps and find you’re still at a standstill, you might benefit from further testing for chronic infections or other lab tests your doctor may deem beneficial. “The more we test, the more we know, so there’s value in it,” says Dr. Rawls. “Testing may help use tailor herbs or other treatments a bit better.”

But testing for chronic infections has its drawbacks due to a lack of sensitivity and reliability. “If you do additional testing and find something, great! We can treat it,” explains Dr. Rawls. “But if you do testing, and it’s negative, you can’t assume other chronic infections aren’t there. So remember, testing is fair at best.”

Ultimately, the choice to test is a decision best made in partnership with you and your healthcare provider. If more information alters the course of treatment and helps you get over this bump in the road, it might be a good idea to pursue it.

The Bottom Line

When it comes to Lyme disease, a plateau can certainly be discouraging. But as you work through the different variables that might be interrupting your healing, you’ll likely discover an area or two in need of attention. As you address those concerns, you’ll begin to experience progress again. Soon, your recovery plateau will become a thing of the past.

Dr. Rawls is a physician who overcame Lyme disease through natural herbal therapy. You can learn more about Lyme disease in Dr. Rawls’ new best selling book, Unlocking Lyme.  You can also learn about Dr. Rawls’ personal journey in overcoming Lyme disease and fibromyalgia in his popular blog post, My Chronic Lyme Journey.

Learn About Dr. Rawls’ Herbal Protocol »
REFERENCES
1. Clancy JA, Deuchars SA, Deuchars J. The wonders of the Wanderer. Exp Physiol. 2013;98(1):38-45. doi: 10.1113/expphysiol.2012.064543
2. Feng J, Shi W, Miklossy J, Tauxe GM, McMeniman CJ, Zhang Y. Identification of Essential Oils with Strong Activity against Stationary Phase Borrelia burgdorferi. Antibiotics (Basel). 2018 Oct 16;7(4):89. doi: 10.3390/antibiotics7040089
3. Prevalence of Building Dampness. Indoor Air Quality Scientific Findings Resource Bank website. https://iaqscience.lbl.gov/dampness-prevalence
 
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**Comment**
 
Hopefully you are under the supervision of a Lyme literate doctor.  Two heads are better than one and the first place to start is to discuss this plateau with your practitioner.  LLMD’s treat many people and have experience and often know just what to use or try to take you to the next step.  For more on LLMDs:  https://madisonarealymesupportgroup.com/2020/11/25/what-makes-a-doctor-lyme-literate/
Another recommendation is to keep a monthly calendar with plenty of space to write down daily symptoms in the box.  Then, from this make a monthly  “executive summary” for your practitioner.  That way you can focus on exact symptoms (and the evolution of them) at your appointment.
 
I also realize many patients live in places where there aren’t any LLMDs.  This often necessitates a self-directed approach with herbs as the only option available.  There are also others where LLMD’s just aren’t affordable and cases where patients haven’t seen improvement on antibiotics – however, there can be many reasons for this:
 
  • wrong antibiotics are being used
  • wrong dosage is being used
  • patient is blaming the antibiotics when it’s often herxheimer reactions causing the horrible symptoms and they just need to push through or take steps to manage these
  • pathogens are causing the symptoms (Bartonella is known to cause GI symptoms)

Since this is unlike anything you’ve ever treated for in the past, it’s hard to understand that you typically feel a whole lot worse before you start feeling better.  It’s also imperative you go on a low or no sugar diet, take plenty of good quality refrigerators pre and probiotics.  

Then there’s the issue of all the other issues that can crop up that have nothing to do with antimicrobial treatment at all such as MCAS, mold, food sensitivities, etc.  These other issues are becoming more common now due to our toxic environment – including electromagnetic radiation.  Some patients have to avoid WiFi altogether.
 
Another point not mentioned in the article is that this really is best described as peeling an onion layer by layer.  You start out with a certain set of symptoms that changes over time.  For instance, when both my husband and I began treatment for Lyme disease, we didn’t notice any Babesia symptoms, but as time wore on and we knocked back a portion of the germ load, all of a sudden we were having air-hunger and chest pressure – common symptoms of Babesia.
 
In my experience few patients have just Lyme disease anymore – particularly if they are chronically/persistently infected.  These complex cases require time and many different antimicrobials in a layered fashion, and most of all – an open mind.

Category:

Herbs, Lyme, Treatment

Rising Geriatric Babesia Cases May Require Longer Treatment

https://danielcameronmd.com/geriatric-babesia-rising-longer-treatment/

GERIATRIC BABESIA CASES ARE RISING AND MAY REQUIRE LONGER TREATMENT

woman with geriatric babesia receiving medication from nurse

The number of Babesia cases among the elderly in the U.S. appears to be growing. According to a study by Menis and colleagues, published in the journal Open Forum Infectious Diseases, 19,469 Medicare beneficiaries had a Babesia diagnosis recorded between 2006 – 2017, with the highest rates occurring in babesiosis-endemic states. [1]

By

Overall, the number of individuals contracting Babesia is rising, as well. The annual number of cases per year climbed from 4 per 100,000 to 9 per 100,000 in the U.S. between 2006 and 2017. The annual number of cases of Babesia per year for individuals over the age of 85 was 4 out of 100,000. In comparison, the number of Lyme disease cases among the elderly was 15.98 per 100,000.

Most of the cases of Babesia occurred in the Lyme-endemic states of Massachusetts, Rhode Island, Connecticut, New York, and New Jersey, according to the authors. Other states recording Babesia cases included Florida, Pennsylvania, California, Maryland, and Virginia. Some cases of Babesia were also reported in New Hampshire, Maine, Vermont, Minnesota, Wisconsin, Texas, North Carolina, and Illinois.

The most common test used to diagnose Babesia was a blood smear in the institutional setting, wrote Menis in a related paper. [2] The intracellular parasite in the red blood cell clears after a few days. The most common tests used in a physician’s office involved antibody or PCR testing. [2]

Co-infections can be deadly

A Babesia infection can be serious for patients.

“Patients co-infected with Lyme disease experienced more symptoms and a more persistent episode of illness than did those (n=10) experiencing babesial infection alone,” wrote Krause and colleagues [3]. In another paper, the authors explain, “Immunocompromised people who are infected by B. microti are at risk of persistent relapsing illness.” [4]

For some patients, including the elderly, a Babesia infection can be more serious. “Babesiosis can be life threatening, particularly for persons who are asplenic, immunocompromised, or elderly,” wrote Krause et al. [4]

85-year-old dies from Babesia and Ehrlichia

Javed and colleagues describe the case of an 85-year-old man who died of a concurrent Babesiosis and Ehrlichiosis infection. [5]

He was an avid gardener and golfer in good health except for hypertension. He did not have a tick bite or rash. The man was hospitalized with weakness and jaundice. He had mild anemia, a very low platelet count, a mildly elevated bilirubin, and mildly reduced renal function.

The doctors diagnosed Babesia based on a bone marrow biopsy revealing intraerythrocytic inclusions (tetrads), typical of babesiosis. In retrospective, his admitting bloods from admission revealed parasitemia in 8% of the red blood cells. The Babesia antibody IgM and IgG were positive for Babesia.

READ MORE: Elderly Lyme disease patients more likely to have unfavorable treatment outcomes

The elderly man was treated with IV clindamycin and IV quinine. His anemia worsened despite transfusion of two units of blood and he was transferred to a tertiary hospital for possible exchange transfusion. The doctor added azithromycin but not Atovaquone.

His condition worsened. His oxygen saturation dropped to 84% and he subsequently developed bilateral pneumonia, renal failure, hepatic failure, and a coma. He was too ill to tolerate exchange transfusion.

He died within 60 hours of admission to the tertiary care center.

Post-mortem tests were positive for Human Monocytic Ehrlichiosis, the cause of Ehrlichia. He was never treated with doxycycline, the most commonly prescribed medication for Ehrlichia.

Treatment of Babesia

Krause and colleagues reported that a 10-day course of Mepron and Zithromax would be as effective as clindamycin and quinine and have less side effects. [3] The Medicare beneficiaries were far more likely to be prescribed Mepron with Zithromax than clindamycin and quinine. [1]

Some patients with Babesia require longer treatment. Krause and colleagues reported immunocompromised and elderly patients were more likely to need longer term therapy.” [4]

In another paper, the authors point out that,

“Such patients generally require antibabesial treatment for >or=6 weeks to achieve cure, including 2 weeks after parasites are no longer detected on blood smear.” [4]

More than one-third of elderly Babesia patients were not treated with anti-Babesia treatment during their evaluation. The study was not designed to determine if the elderly were subsequently treated.

IDSA position

The 2020 Infectious Diseases Society of America (IDSA) guidelines for Babesia highlighted concerns regarding severe Babesia in the elderly.

“Numerous immunodeficiencies and comorbidities have been associated with severe babesiosis, including asplenia and hyposplenism, cancer, congestive heart failure, HIV infection, immunosuppressive drugs, and advanced age.” [6]

For immunocompromised patients, we suggest monitoring Babesia parasitemia using peripheral blood smears even after they become asymptomatic and until blood smears are negative. PCR testing should be considered if blood smears have become negative but symptoms persist (weak recommendation, moderate-quality evidence).

In addition, the IDSA guidelines advised longer treatment for immunocompromised Babesia patients.

“A subgroup of highly immunocompromised patients reported in a case control study required at least 6 consecutive weeks of antibiotic therapy, including 2 final weeks during which parasites were no longer detected on peripheral blood smear.” [6]

However, some patients can relapse.

“A few cases of relapse despite at least 6 consecutive weeks of atovaquone plus azithromycin demonstrate that resistance to atovaquone and/or azithromycin can emerge in highly immunocompromised patients during an extended course of this antibiotic combination,” wrote Krause et al. [6]

Editor’s note: I share the same concerns regarding Babesia in the elderly, and I base the length of antibiotics on the patient’s response to treatment.

Related Articles:

Tick bite causes 3 diseases in elderly woman

Lyme disease mimics autoimmune disorder in elderly woman

Podcast: Confusion in elderly woman with anaplasmosis and babesia infection

References:
  1. Menis M, Whitaker BI, Wernecke M, et al. Babesiosis Occurrence among the U.S. Medicare Beneficiaries Ages 65 and Older, During 2006-2017: Overall, and by State and County of Residence. Open Forum Infectious Diseases. 2020
  2. Menis M, Forshee RA, Kumar S, McKean S, Warnock R, Izurieta HS, Gondalia R, Johnson C, Mintz PD, Walderhaug MO, Worrall CM, Kelman JA, Anderson SA. Babesiosis Occurrence among the Elderly in the United States, as Recorded in Large Medicare Databases during 2006-2013. PLoS One. 2015 Oct 15;10(10)
  3. Krause PJ, Telford SR, 3rd, Spielman A, et al. Concurrent Lyme disease and babesiosis. Evidence for increased severity and duration of illness. JAMA. Jun 5 1996;275(21):1657-60.
  4. Krause PJ, Gewurz BE, Hill D, et al. Persistent and relapsing babesiosis in immunocompromised patients. Clin Infect Dis. Feb 1 2008;46(3):370-6. doi:10.1086/525852
  5. Javed MZ, Srivastava M, Zhang S, Kandathil M. Concurrent babesiosis and ehrlichiosis in an elderly host. Mayo Clin Proc. May 2001;76(5):563-5. doi:10.4065/76.5.563
  6. Krause PJ, Auwaerter PG, Bannuru RR, et al. Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA): 2020 Guideline on Diagnosis and Management of Babesiosis. Clin Infect Dis. Nov 30 2020;doi:10.1093/cid/ciaa1216

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For more:  https://madisonarealymesupportgroup.com/2016/01/16/babesia-treatment/

Mainstream medicine still does not believe the seriousness of this complex illness that thousands upon thousands are suffering from.  The interaction of confections make cases extremely difficult to treat.  Do not mess around with this, get to a Lyme literate doctor asap:  https://madisonarealymesupportgroup.com/2020/11/25/what-makes-a-doctor-lyme-literate/  These doctors typically layer treatment to reduce any potential of resistance to treatment.  We often took 4 things simultaneously.

Category:

Babesia, research, Treatment

Understanding Mycoplasma: Symptoms, Testing, & Treatment

https://rawlsmd.com/health-articles/mycoplasma-the-most-common-lyme-coinfection

Understanding Mycoplasma: Symptoms, Testing, and Treatment | RawlsMD

Mycoplasma: The #1 Lyme Coinfection + How to Outsmart It

by Dr. Bill Rawls
Updated 12/9/20

Mycoplasma is the stealthiest of all stealth microbes. It may be a major player in many chronic diseases associated with aging, but remarkably, most people — including most doctors — have limited awareness of it.

If you have Lyme disease, fibromyalgia, chronic fatigue syndrome, autoimmune disease, or possibly any other chronic illness, however, mycoplasma is a microbe you should know about.

Mycoplasma: The Master Manipulator

Mycoplasma is a parasite, meaning it can’t live without a host. And it’s the smallest of all bacteria: 4,000 of them can fit inside a single red blood cell in your body. By comparison, only 10-15 average-sized bacteria would fit in the same cell.

Unlike other bacteria, mycoplasmas don’t have a protective cell wall, creating an interesting survival strategy: They can shape-shift and fit into areas where other bacteria can’t go. For example, it also allows them to slip inside cells of the host. The lack of a cell wall makes mycoplasma resistant to some commonly prescribed classes of antibiotics like penicillins, which normally work by interrupting a bacteria’s cell wall so that when the bacteria divides, it falls apart.

More than 200 known types of mycoplasma (and probably many yet to be discovered) can infect animals and plants. There are at least 23 different varieties of mycoplasma that can infect humans. A few of them are considered harmless normal flora, but most have the potential to cause disease.

image split in three: tick, flea, and mosquito

Mycoplasma is spread by biting insects (ticks, mosquitoes, fleas, biting flies), sexual contact, contaminated food, and airborne droplets. Most everyone has been exposed to some form of mycoplasma. Several mycoplasma species have been closely associated with many chronic degenerative diseases like multiple sclerosis and Alzheimer’s disease, according to publications like the International Reviews of Immunology and the British Journal of Medical Practitioners, respectively.

Even beyond its tiny size, shape-shifting qualities, and proliferous nature, mycoplasma is a master at manipulating and outmaneuvering the host’s immune system. Half of its genetic makeup is devoted to that exclusive purpose.

While it has little ability to cause direct harm, it can use the host’s immune function to its advantage: Mycoplasma generates chronic low-grade inflammation and steals vital nutrients from the body.

In fact, everything that this stealthy microbe needs for survival — vitamins, minerals, fats, carbohydrates, and amino acids — must be scavenged from the host; it makes nothing itself. Mitochondria, which are the energy powerhouses of cells, are prime targets to sustain the microorganism, which helps explain why fatigue is always a factor in mycoplasma infections.

Mycoplasma favors infecting the cells of tissues that line different areas of the body. Common sites of infection include:

  • Nasal passages
  • Sinuses
  • Lungs
  • Lining of the intestinal tract
  • Genital tract
  • Vesicles inside the brain
  • Synovial lining of joints

They also commonly infect white blood cells, red blood cells, and brain tissue. Different mycoplasma has a preference for certain tissues, but all mycoplasma species possess the ability to infect any type of tissue and all organ systems.

The most common mycoplasma, Mycoplasma pneumoniae, has a preference for lung tissue. Initial infection with M. pneumoniae typically causes pharyngitis (sore throat), cough, fever, headache, malaise, runny nose — all the common symptoms of a basic upper respiratory infection.

man wrapped in blanket, coughing

If the person’s immune system is not full strength, the infection can progress to bronchitis and even pneumonia (about 20% of pneumonias). The type of pneumonia caused by mycoplasma, often called “walking pneumonia,” is rarely severe enough to result in hospitalization, though it can drag on for weeks or even months.

But even when those respiratory symptoms are cleared, it may not be the end of the story. That’s because after mycoplasma enters the body, it also infects white blood cells. And once inside a white blood cell, it can be carried to all parts of the body, infecting tissues and organs.

The potential for widespread infection is very much influenced by the status of the host’s immune function. If immune function is optimal, the microbe is contained after the initial infection, and no long-term harm occurs. Approximately 30-70% of people carry at least one species of mycoplasma without having symptoms. It essentially becomes like normal flora of the microbiome, which are the non-threatening microbes found on the skin, in the gut, and body cavities.

But most mycoplasma species aren’t normal flora, and they are just waiting for an opportunity to gain a foothold. If immune function slips for whatever reason, chronic, systemic infection becomes possible. Mycoplasma begins stealing vital nutrients and causing a wide range of symptoms that are unrelated to the initial infection. The general breakdown of tissues by stealth microbes like mycoplasma accelerates the aging process and is likely a primary factor in many, if not most, chronic degenerative diseases.

Stealth Characteristics of Mycoplasma

Stealth microbes are a stronger force together than when alone. In other words, mycoplasma may not be a problem unless another stealth microbe (or microbes) is present. Lyme disease may be a good example of this phenomenon.

image split in half: borrelia and mycoplasma

Mycoplasma is a common Lyme coinfection: It’s present in 75% or more of Lyme disease cases. Mycoplasma is known to be carried and spread by ticks, but it is also possible that mycoplasma is already present in the body when a bite from a tickcarrying borrelia — the primary bacteria associated with Lyme — occurs.

Immune dysfunction caused by the new tick-borne infection or possible other coinfection allows mycoplasma to proliferate and cause multi-systemic symptoms throughout the body. Many symptoms that occur in Lyme disease can be caused by mycoplasma, too.

Body Systems Affected by Chronic Mycoplasma

woman in bed, face in hand, tired

Mycoplasma infection may be localized to certain areas of the body (such as the lungs), or it can be more widespread and systemic. Parts of the body where symptoms can manifest include:

  • Joints: Mycoplasma commonly infects the synovial lining of joints, the lining protecting the joints. Ninety percent of people with rheumatoid arthritis test positive for mycoplasma in the synovial fluid.
  • Muscles: Muscle pain from breakdown of muscle fibers is common with systemic mycoplasma infection.
  • Heart: Mycoplasma can lead to inflammation of the heart, such as endocarditis, myocarditis, pericarditis.
  • Nerves: Mycoplasma scavenges fats from the myelin sheath covering nerve tissue. Not surprisingly, mycoplasma (and other microbes, including chlamydiaand borrelia) has been linked to multiple sclerosis and other neurodegenerative diseases, including ALS (Mycoplasma fermentans is most common) and Parkinson’s disease.

    Nerve involvement can be associated with neuropathic pain like burning and tingling in the hands and feet. Brain inflammation, contributing to insomnia, brain fog, depression, and anxiety, is common with systemic mycoplasma infection.

  • Immune system: Mycoplasma is a top candidate for explaining autoimmunity; it stimulates host self-damage, and it can live inside cells while simultaneously turning off the ability of the immune system to recognize the cell as abnormal.
  • Lungs: Mycoplasma in the lungs contributes to respiratory symptoms like sore throat, cough, fever, headache, malaise, runny nose, bronchitis, and pneumonia.
  • Digestive tract: Intestinal mycoplasma infection destroys villi — fingerlike projections in the small intestine that aid food absorption — and compromises the intestinal barrier. This allows accelerated damage by lectins in grains (especially wheat), beans, soy, nightshade vegetables, and dairy.

    Mycoplasma may contribute to leaky gut, or increased intestinal permeability. Severe mycoplasma intestinal infection can lead to nutritional deficiencies and weight loss. Infection of the gastric mucosa (stomach lining) can cause chronic gastritis with nausea and stomach discomfort.

  • Ears: Mycoplasma infection has been associated with hearing loss and ringing in the ears.
  • Eyes: The eyes may be impacted by mycoplasma with such issues as conjunctivitis, eye swelling, and vision loss.
  • Reproductive system: Research suggests mycoplasma has been found in ovarian cancer tissue. It may also contribute to interstitial cystitis, a bladder condition marked by severe pain and urinary frequency.
  • Blood: Mycoplasma has been found in the bone marrow of children with leukemia.

Diagnosing Mycoplasma and the Limitations of Testing

When it comes to testing, PCR (polymerase chain reaction) is the most accurate method for testing mycoplasma. It’s cost-effective and evaluates for the presence of mycoplasma’s genetic material, a test that’s easy, sensitive, and quick test to obtain at most laboratories.

However, PCR testing has limits because it only tests for a handful of mycoplasma species and primarily focuses on diagnosing acute respiratory or genital mycoplasma infections — not chronic, low-grade infections.

Female forensic technician collecting biological specimen in DNA

Another problem with diagnosing mycoplasma is that conventional science does not recognize chronic mycoplasma infections as being significant. Even though mycoplasma is commonly found in association with chronic degenerative diseases, it’s also found in one-third to two-thirds of any population without causing symptoms. In other words, it is assumed that mycoplasma just happens to be there but isn’t really a contributing factor in disease.

This type of thinking is simply a reflection of not understanding how stealth microbes operate. Mycoplasma does not cause disease unless it has an opportunity to do so. Individuals with a healthy immune system can harbor mycoplasma and suffer few ill effects. If immune function is disrupted by environmental factors or a coinfection with other stealth microbes, however, mycoplasma can definitely contribute to chronic disease.

When testing for mycoplasma, it is best to order a complete PCR mycoplasma panel, which will include:

  • M. fermentans
  • M. genitalium
  • M. hominis
  • M. penetrans
  • M. pneumoniae
  • M. synoviae
  • Ureaplasma urealyticum

But these are only the commonly-known species of mycoplasma; other lesser-known species could also be present.

Another problem with testing is that other stealth microbes can be associated with chronic infections with similar symptoms of mycoplasma infection, adding confusion to the clinical picture of what’s making a person ill. The list of knowns includes:

  • Yersinia enterocolitica
  • Chlamydophila pneumoniae
  • Chlamydia trachomatis
  • Campylobacter jejuni
  • Babesia
  • Bartonella
  • Ehrlichia
  • Anaplasma

Laboratories that test for mycoplasma include Medical Diagnostic Laboratories (MDL)and Armin Labs. Your healthcare provider may have additional recommendations for you.

But complete testing for the full range of all stealth microbes can cost hundreds or even thousands of dollars. Possibly the best course of action is assuming mycoplasma and other stealth microbes are there.

Stealth microbes only cause problems when immune function is suppressed. Addressing the causes of the underlying chronic immune dysfunction that allowed mycoplasma to flourish in the first place is the most effective solution for overcoming chronic infections.

Conventional Medical Solutions

The nature of mycoplasma makes it very resistant to conventional therapies. Many antibiotics target cell walls; since mycoplasma doesn’t have one, several classes of antibiotics are ineffective against the microbe. Some other antibiotics (doxycycline, erythromycin, clarithromycin, or azithromycin), block internal functions of bacteria and have some activity against mycoplasma, but activity is limited by the fact that mycoplasma bacteria only live inside cells where antibiotics have minimal penetration.

When it comes to chronic mycoplasma infections, the best approach is supporting the body’s natural healing potential.

Natural Solutions for Mycoplasma

Natural herbal therapy is the best therapeutic alternative for chronic mycoplasma. Herbs (especially medicinal mushrooms) work by:

  • Suppressing cytokine cascades
  • Reducing inflammation
  • Restoring normal immune function
  • Suppressing a wide range of covert pathogens

Consider the following herbs to get you started:

Cordyceps mushroom

Cordyceps (Cordyceps sinensis)

Native to Tibet, cordyceps is a medicinal mushroom that reduces cytokines and normalizes immune system functions. It is highly protective of cells, which reduces invasion by microbes.

Suggested dosage: 1-3 grams (1,000-3,000 mg) of whole mushroom cordyceps powder or 400-800 mg extract (standardized to >7% cordyceptic acid is preferred) two to three times daily.

Side effects: Mild nausea can occur, but in general, side effects are rare, even with higher doses. Allergic reactions are rare.

Chinese Skullcap purple flowers

Chinese Skullcap (Scutellaria baicalensis)

When combined with other herbs, Chinese skullcap has potent synergist properties. Additionally, it has strong antimicrobial and immunomodulating properties that are beneficial for suppressing mycoplasma and protecting tissues and organs infected with the microbe.

Suggested dosage: 400-1,000 mg two to three times daily. Root extract standardized to >30% baicalin is preferred. Note: American skullcap does not offer the same antimicrobial properties and should not be substituted.

Side effects: Gastrointestinal upset can occur, but side effects tend to be rare, even at high doses.

white Bidens flowers

Bidens (Bidens pilosa)

The herb offers potent antimicrobial and anti-inflammatory properties against mycoplasma, affecting mucous membranes of the body.

Suggested dosage: Bidens is most potent when prepared as an alcohol tincture. The dose may vary depending on the company, but tinctures are an excellent way to begin at a low dose and increase drops as tolerated.

Side effects: Some plants can be contaminated with heavy metals, so make sure you purchase the product from a reputable company that takes steps to minimize exposure. You should not take this plant if you are diabetic, as it can cause fluctuations in blood glucose or insulin levels.

Houttuynia white flower

Houttuynia (Houttuynia cordata)

Native to India and Nepal, houttuynia is a potent antiviral with activity also against mycoplasma.

Suggested dosage: The dose may vary depending on a company’s preparations.

Side effects: The herb can have a fishy smell but is otherwise well tolerated.

budding Anamu stem

Anamu (Petiveria alliacea)

Found in tropical, Amazonian regions of Central and South America, anamu offers excellent antimicrobial coverage for mycoplasma.

Suggested dosage: The daily dose of powdered herb is 1,000-2,000 mg twice daily.

Side effects: Note that anamu will give urine and feces a strong garlic-like odor. Generally, the herb is safe and well-tolerated, but it should be avoided in pregnancy.

Mullaca leaf berry

Mullaca (Physalis angulata)

Mullaca is another Amazonian herb with antimicrobial qualities to fight mycoplasma, and it works well as a complement to anamu. It can be found online as a loose powder (add it to smoothies or make your own capsules) or a tincture.

Suggested dosage: The daily dose for powdered herb is 1,000-2,000 mg twice daily.

Side effects: The herb is generally regarded as safe, however, it should be avoided during pregnancy or breastfeeding.

The Bottom Line

In addition to herbal therapy, the optimal path to recovery from chronic mycoplasma involves eliminating artificially-processed foods in favor of whole, nutrient-dense meals, reducing exposure to toxins, and managing chronic stress — all of which disrupt immune function and pave the way for stealth microbes to flourish. By minimizing these factors and implementing a comprehensive herbal therapy protocol, you can begin to curb chronic mycoplasma infections and support your body in the healing process.

Dr. Rawls is a physician who overcame Lyme disease through natural herbal therapy. You can learn more about Lyme disease in Dr. Rawls’ new best selling book, Unlocking Lyme.
You can also learn about Dr. Rawls’ personal journey in overcoming Lyme disease and fibromyalgia in his popular blog post, My Chronic Lyme Journey.

Learn About Dr. Rawls’ Herbal Protocol »
REFERENCES
1. K Waites and D Talkington, Mycoplasma pneumoniae and its Role as a Human Pathogen, Oct 2004, Clinical Microbiology Reviews
2. Hakkarainen, Turrunen, Miettinen, Kaitik, and Jannson, Mycoplasmas and Arthritis, Ann Rheu Dis, 1992, Oct 5 (11): p. 1170-1172
3. Baseman, Joel, et.al., Mycoplasmas: Sophisticated, Reemerging, and Burdened by Their Notoriety, CDC, Journal of Infectious Diseases, Vol 3, No.1, Feb 1997
4. Leslie Taylor, ND, Mycoplasmas – Stealth Pathogens (Review article), Jan 2001
5. Razin, Yogev, Naot, Molecular Biology and Pathogenicity of Mycoplasmas, Microbiol Mol Biol Rev, 1998, Dec; 62(4): p. 1094-1156
6. J Rivera-Tapia, N Rodriguez-Preval, Possible role of mycoplasmas in pathogenesis of gastrointestinal diseases, Rev Biomed 2006 17: 132-139
7. Berghoff, W, Chronic Lyme Disease and Co-infections: Differential Diagnosis, Open Neurol J., 2012, 6, p. 158-178
8. Gilroy, Keat, Taylor-Robinson, The Prevalence of Mycoplasma fermentans in patients with arthritides, Rheumatology, Vol 40 (12), p. 1355-1358
9. Zhang et al, Mycoplasma fermentans infection promotes immortalization of human peripheral blood mononuclear cells in culture, Blood 104 (13), p. 4252-4259
10. Walter Berghoff, Chronic Lyme Disease and Co-infections: Differential Diagnosis, Open Neurol J, 2012, 6: p. 158-178
11. Buhner S H, Healing Lyme Disease Coinfections, Healing Arts Press, Copyright 2013 http://www.cdc.gov/pneumonia/atypical/mycoplasma/index.html
12. Libbey JE, Cusick MF, Fujinami RS. Role of pathogens in multiple sclerosis. Int Rev Immunol. 2014;33(4):266-283. doi: 10.3109/08830185.2013.823422
13. BJMP 2009:2(4) 20-28
14. Huang S, Li JY, Wu J, Meng L, Shou CC. Mycoplasma infections and different human carcinomas. World J Gastroenterol. 2001;7(2):266-269. doi: 10.3748/wjg.v7.i2.266
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Category:

mosquitoes, Mycoplasma, Testing, Ticks, Treatment

Fareed/Tyson COVID-19 Treatment Protocol

https://www.thedesertreview.com/news/dr-george-fareed-and-dr-brian-tyson-share-early-treatment-protocol/article

Dr. George Fareed and Dr. Brian Tyson share early treatment protocol

Updated

Dr. George Fareed, Imperial Valley frontline doctor fighting against the COVID-19 pandemic locally, has been fielding phone calls from across the nation helping those afflicted but unable to get early treatment from their medical establishments.

“I’m really busy, but I’m willing to help anyone,” Fareed said.

(See link for article)

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Excerpt:

Fareed/Tyson COVID-19 Treatment Protocol
  • HCQ 200 mg tabs #16 (HCQ = hydroxychloroquine)
  • Zinc sulfate 22O mg (or elemental Zinc 50 mg) # 15
  • Azithromycin 500 mg # 5 (or Z pack) or
  • Doxycycline 100 mg # 10)
  • Ivermectin 3 mg tabs #8
  • Aspirin 325 mg tabs #30 
Day 1
  • HCQ 2 tabs twice a day
  • Zinc sulfate tab twice a day
  • (Azithromycin tab one per day or doxycycline cap twice a day)
  • Ivermectin 12 mg on day 1 only
  • Aspirin 325 mg 
Days 2-5 
  • HCQ tab 3 times a day
  • Zinc sulfate 3 times a day
  • (Azithromycin tab daily or doxycycline cap twice a day)
  • Aspirin 325 mg daily
  • Ivermectin 12 mg on day 3 if symptoms warrant 
  • Prednisone 60 mg daily x 5-7 days or
  • Dexamethasone 4 mg bid if wheezing /SOB
  • Budesonide 0.5-1mg/2ml vía nebulizer bid 
  • Vitamin D3 5000 iu daily
  • Pepcid 20 mg daily
  • Continue daily Aspirin 325 mg
Over the counter prevention:
  • Elemental Zinc 25 mg once a day
  • Vitamin D 4000 iu once a day
  • Vitamin C 1000 mg once a day 
  • Quercetin 500 mg once a day. If Quercetin is unavailable, then use Epigallocatechin-gallate (EGCG) 400mg once a day

Protocols for low, medium, and high risk patients are also included.

For more on COVID treatments:  

 

Category:

Treatment, Viruses

Lyme & Morgellons Disease: The Growing Connection

https://rawlsmd.com/health-articles/lyme-morgellons-disease-the-growing-connection

Lyme + Morgellons Disease: The Growing Connection

Lyme + Morgellons Disease: The Growing Connection

by Jenny Lelwica Buttaccio
Posted 12/21/2020

On the surface, it has all the makings of a medical drama episode on a mystery illness: unexplained skin lesions, a widespread set of symptoms impacting physical and mental health, and contested medical debates over its validity. In real life, it’s known as Morgellons disease, an illness that affects 3.65 in 100,000 people each year, according to research in the online, peer-reviewed medical journal PLOS One.

In other words, it’s quite rare by medical community standards, but it’s no less distressing or life-altering for those who endure it. And while the cause of Morgellons is a matter of hot debate, emerging research suggests ties to Lyme disease and common coinfections.

A Closer Look at Morgellons Disease

Morgellons often presents with puzzling dermatological symptoms. Patients describe a variety of unusual skin problems such as unexplained sores containing colored, thread-like structures or filaments, intense itching, and sensations of crawling or being stung by insects. Patients may also report other phenomena like flecks or particles emerging from the skin that resemble sand, seeds, or other tiny granules.

Currently, the cause of the illness remains unknown, and arguments about whether the disease is psychological or physical have ensued. Some healthcare professionals believe Morgellons is psychological — the result of a kind of delusion known as “delusional parasitosis.”

Medical doctor and patient discussing and consulting in hospital examination room

In a delusion such as this, patients may hold an unwavering belief they have been infested with parasites, fleas, worms, lice, or other types of organisms. The problem with this theory, however, is that Morgellons patients often have multi-systemic symptoms that parasites alone don’t explain such as fatigue, joint pain, fibromyalgia, and difficulty sleeping, as stated in a case report in the Annals of Dermatology.

Previously, some clinicians believed the filaments in the skin might have come from textile fibers or, worse, placed there by the patients themselves. However, a 2013 study sheds new light on the illness by evaluating colored filaments from tissue specimens gathered from the calluses of four female patients. The findings revealed the filaments weren’t comprised of textiles or synthetic materials at all. Instead, they were made up of substances in the body, including keratin, melanin, collagen, and other proteins.

Moreover, researchers discovered the presence of borrelia species of spirochetes in the participants’ tissue samples, indicating an infectious process might be one of the underlying mechanisms behind this illness. The multi-symptom illness overlaps with the symptoms of chronic Lyme disease and coinfections, but with only small-scale research on the topic, there are many layers yet to peel back.

“It bothers me on all the accounts that some physicians have blown off Morgellons patients or accused them of putting fibers into their tissues,” says Bill Rawls, MD, Medical Director of RawlsMD and Vital Plan. “When you look at how microbes like borrelia work and how they destroy collagen, it’s plausible that they are an underlying factor in this illness.”

Immune reaction. Admirable worried pretty girl visiting her doctor who carefully studying red spots on her skin while wearing medical gloves

In a 2016 study, researchers suggest the “dermopathy” (patches, spots, or lesions on the skin) of Morgellons is connected to tick-borne diseases, and they’ve discovered several species of borrelia in skin specimens: Borrelia burgdorferi (the predominant species causing Lyme disease), Borrelia garinii, Borrelia miyamotoi, and Borrelia hermsii.

“Morgellons may be a variant of Lyme disease that happens to affect the skin,” says Dr. Rawls. But it may develop in only a fraction of people who contract the tick-borne disease.

To date, there is no consensus on what causes Morgellons or why it affects some people and not others. Despite an association with borrelia, many health experts remain skeptical that the illness is brought about by an infection. Though Morgellons is a misunderstood and controversial illness, funding is needed for research, and awareness is of the utmost importance so that patients can get an accurate diagnosis.

Let’s explore some of the signs, symptoms, diagnostics, and treatment strategies for Morgellons.

Symptoms of Morgellons Disease

People with Morgellons can have a variety of symptoms, affecting multiple systems of the body. The symptoms include:

Diagnosing Morgellons Disease

Morgellons can be difficult to diagnose, notes Dr. Rawls, especially if healthcare providers don’t know enough about the illness to look for it. The Charles E. Holman Morgellons Disease Foundation (CEHF), a nonprofit aimed at supporting awareness, education, and advocacy efforts, recommends seeing a Lyme-literate medical doctor (LLMD) to evaluate the presence of Lyme or other tick-borne diseases.

There isn’t a specific test to detect for Morgellons, but doctors may diagnose it if a person has slow or non-healing wounds, fibers in the lesions, or crawling or itching sensations of the skin. Skin samples may be tested for the presence of bacterial infections like Borrelia burgdorferi or Staphylococcus. Lyme specialists may also use testing from laboratories such as Igenex to confirm whether Lyme may be a factor in the illness.

Treatment of Morgellons Disease

There is no singular approach to the treatment of Morgellons that will work for everyone. Realistically, there’s a lot of trial and error to figure out what strategies will be most effective for the illness.

A good treatment approach focuses on comprehensive ways to improve multi-systemic symptoms and address pathogens such as borrelia and coinfections like bartonella and babesia. Treatment protocols may also include topical medications to address infections of skin lesions or referrals to mental health professionals if psychiatric manifestations of the illness occur.

Incorporating Herbal Therapy

Natural remedies might play a role in managing symptoms and helping you feel better as well. “Because borrelia may be a component of Morgellons disease, I think herbal therapy is an essential foundation to a recovery program,” says Dr. Rawls. Though there’s a lot we still don’t know about the illness, herbs suppress a variety of harmful microbes, balance the immune system, and improve energy — all of which will have a positive effect on symptoms.

Though herbs aren’t a proven method of treatment for Morgellons, they have a low risk for toxicity and side effects. So it might be worth discussing the benefits and risks with your healthcare provider to see if natural therapies could help restore your health. Some foundational herbs to explore include:

cats claw bark

Cat’s Claw

Cat’s claw is native to the Amazon region. The herb is a staple among Lyme disease protocols due to its antimicrobial qualities. It also contains immune-modulating properties to quiet an overactive immune system and reduce inflammation. It has historical use in alleviating the pain associated with arthritis, too.

Suggested dosage: 400-800 mg two to three times daily (inner bark standardized to 3% alkaloids or 10:1 concentrate inner bark is preferred). It is especially important to take this herb with food, as it is activated by stomach acid. If you take acid-blocking drugs, cat’s claw won’t have a significant impact on you.

Side effects: The herb is generally well tolerated, but occasional stomach upset has been reported.

andrographis white flower on green leaves

Andrographis

Native to India, andrographis has antibacterial, antiviral, and antiparasitic properties to defend against a spectrum of microbes. The herb has immune-enhancing, cardioprotective, and liver-protective qualities. Like cat’s claw, andrographis is a staple among natural Lyme protocols.

Suggested dosage: 200-800 mg (extract standardized to 10-30% andrographolides) two to three times daily

Side effects: Approximately 1% of people who take andrographis develop an allergic reaction with whole-body hives and itching skin. This is a higher percentage than most other herbs. The reaction will resolve gradually over several weeks once the herb has been discontinued.

red berberine berries hanging from steam

Berberine

Berberine is an antimicrobial herb and helps to restore balance to the microbiome.

Suggested dosage: The dose will vary depending on the preparation used.

Side effects: In most cases, berberine is generally well tolerated. Side effects may include gastrointestinal discomfort and low blood pressure.

full garlic bulbs

Garlic

Garlic has been used for medicinal purposes since the beginning of recorded time. The active ingredient in garlic is called allicin, and it has antiprotozoal, antiviral, and antifungal properties. Also, it assists in supporting the immune system and balancing the flora of the microbiome.

Suggested dosage: 180-1200 mg of a stabilized allicin product two to three times daily (dosage is dependent on the garlic preparation used)

Side effects: Raw garlic may cause stomach upset, but stabilized allicin products are associated with few side effects and are generally well tolerated.

orange reishi mushrooms

Reishi Mushroom

As a medicinal mushroom, reishi contains adaptogen properties and is antimicrobial and immune-modulating. The herb reduces inflammatory cytokines and supports the immune system’s ability to combat pathogens. Reishi supports the liver and heart as well.

Suggested dosage: 1-2 grams (1000-2000 mg) whole mushroom powder or 150-500 mg standardized extract (minimum 20% beta-glucans preferred) two to three times daily.

Side effects: Reishi tends to be well tolerated with rare side effects and no known toxicity.

purple chinese skullcap flowers

Chinese Skullcap

As a multi-purpose herb, Chinese skullcap has antimicrobial properties, dampens cytokines, and supports immunity. It works synergistically with other herbal remedies to enhance their effectiveness. It also has naturally-occurring melatonin, which may help to induce sleep.

Suggested dosage: 400-1000 mg two to three times daily. Note that American skullcap does not offer the same antimicrobial properties and should not be substituted.

Side effects: Even at high doses, side effects are rare and often limited to gastrointestinal discomfort.

Helpful Resources

The following list provides further information about Morgellons and helpful organizations. (A special thank you to CEHF, who assisted in compiling these resources.)

  • Charles E. Holman Morgellons Disease Foundation (CEHF): A nonprofit geared toward education, advocacy, and awareness of the illness
  • BCA Clinic: A clinic in Germany specializing in the treatment of tick-borne diseases, including Morgellons
  • Donovan Hair Clinic: A Canadian hair clinic led by dermatologist Jeff Donovan, MD, PhD, specializing in hair loss and Morgellons disease
  • Morgellons: The Legitimization of a Disease: A book aimed at separating fact from fiction regarding the condition and serving as a resource to patients and caregivers
  • Oklahoma State University Center for Health Sciences: Provides information and education and is advancing the knowledge of Morgellons through research
  • Skin Deep: The Battle Over Morgellons: A documentary chronicling a nurse’s quest to discover the truth about the disease as she confronts skeptics in the medical community

Final Thoughts

“We don’t know that much about Morgellons yet, and our perception is that it’s not that common,” says Dr. Rawls. Therefore, he warns that many patients will likely see several doctors before finding one who is willing to investigate the root cause more thoroughly and try various treatment approaches.

“When physicians are confronted with something they don’t know, they have two choices: One is to look further into it. The other is to try to make things go away as fast as possible,” says Dr. Rawls. “I hope we can become the type of medical community who looks further into it and seeks to help Morgellons patients as best as we can.”

Dr. Rawls is a physician who overcame Lyme disease through natural herbal therapy. You can learn more about Lyme disease in Dr. Rawls’ new best selling book, Unlocking Lyme.
You can also learn about Dr. Rawls’ personal journey in overcoming Lyme disease and fibromyalgia in his popular blog post, My Chronic Lyme Journey.

Learn About Dr. Rawls’ Herbal Protocol »
REFERENCES
1. Delusional Parasitosis. Merck Manual website.
https://www.merckmanuals.com/home/skin-disorders/parasitic-skin-infections/delusional-parasitosis
2. Latest Information. Charles E. Holman Morgellons Disease Foundation website. https://thecehf.org/
3. Middelveen MJ, Mayne PJ, Kahn DG, Stricker RB. Characterization and evolution of dermal filaments from patients with Morgellons disease. Clin Cosmet Investig Dermatol. 2013;6:1-21. doi:10.2147/CCID.S39017
4. Ohn J, Park SY, Moon J, Choe YS, Kim KH. Morgellons Disease. Ann Dermatol. 2017;29(2):223-225. doi:10.5021/ad.2017.29.2.223
5. Pearson ML, Selby JV, Katz KA, Cantrell V, Braden CR, Parise ME, Paddock CD, Lewin-Smith MR, Kalasinsky VF, Goldstein FC, Hightower AW, Papier A, Lewis B, Motipara S, Eberhard ML; Unexplained Dermopathy Study Team. Clinical, epidemiologic, histopathologic and molecular features of an unexplained dermopathy. PLoS One. 2012;7(1):e29908. doi: 10.1371/journal.pone.0029908
6. Savely VR, Stricker RB. Morgellons disease: Analysis of a population with clinically confirmed microscopic subcutaneous fibers of unknown etiology. Clin Cosmet Investig Dermatol. 2010;3:67-78. Published 2010 May 13. doi:10.2147/ccid.s9520
 
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Category:

Lyme, Morgellons, research, Treatment, Uncategorized