Madison Area Lyme Support Group

A North Carolina State University researcher has discovered that bacteria transmitted by fleas–and potentially ticks–can be passed to human babies by the mother, causing chronic infections and raising the possibility of bacterially induced birth defects.

Dr. Ed Breitschwerdt, professor of internal medicine in the Department of Clinical Sciences, is among the world’s leading experts on Bartonella, a bacteria that is maintained in nature by fleas, ticks and other biting insects, but which can be transmitted by infected cats and dogs as well. The most commonly known Bartonella-related illness is cat scratch disease, caused by B. henselae, a strain of Bartonella that can be carried in a cat’s blood for months to years. Cat scratch disease was thought to be a self-limiting, or “one-time” infection; however, Breitschwerdt’s previous work discovered cases of children and adults with chronic, blood-borne Bartonella infections–from strains of the bacteria that are most often transmitted to cats (B. henselae) and dogs (B. vinsonii subsp. berkhoffii) by fleas and other insects.

In his most recent case study, Breitschwerdt’s research group tested blood and tissue samples taken over a period of years from a mother, father and son who had suffered chronic illnesses for over a decade. Autopsy samples from their daughter–the son’s twin who died shortly after birth–contained DNA evidence of B. henselae and B. vinsonii subsp. berkhoffi infection, which was also found in the other members of the family.

Both parents had suffered recurring neurological symptoms including headaches and memory loss, as well as shortness of breath, muscle weakness and fatigue before the children were born. In addition, their 10-year-old son was chronically ill from birth and their daughter died due to a heart defect at nine days of age.

Results of the parents’ medical histories and the microbiological tests indicated that the parents had been exposed to Bartonella prior to the birth of the twins, and finding the same bacteria in both children, one shortly after birth and the other 10 years later, indicates that they may have  become infected while in utero.

Breitschwerdt’s research appears online in the April 14 Journal of Clinical Microbiology.

“This is yet more evidence that Bartonella bacteria cause chronic intravascular infections in people with otherwise normal immune systems, infections that can span a decade or more,” Breitschwerdt says. “Also this new evidence supports the potential of trans-placental infection and raises the possibility that maternal infection with these bacteria might also cause birth defects.”

The Department of Clinical Sciences is part of NC State’s College of Veterinary Medicine. Dr. Breitschwerdt is also an adjunct professor of medicine at Duke University Medical Center.

Note to editors: An abstract of the paper follows.

“Molecular evidence of perinatal transmission of Bartonella vinsonii subsp. berkhoffii and B.henselae to a child”
Authors: Edward B. Breitschwerdt, Ricardo G. Maggi and Patricia E. Mascarelli, NC State University; Peter Farmer, Department of Pathology, North Shore University Hospital
Published: April 14, 2010 in Journal of Clinical Microbiology

Abstract:
Bartonella vinsonii subsp. berkhoffii, Bartonella henselae or DNA of both organisms was
amplified and sequenced from blood, enrichment blood cultures or autopsy tissues from four family members. Historical and microbiological results support perinatal transmission of Bartonella species in this family.

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**Comment**

If it weren’t for the work of this singular man, we’d be clueless about the implications of Bartonella.  Heavily vested in finding answers due to his father’s death to Bartonella, Dr. Breitschwerdt is the only one currently looking at congenital transmission:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044516/#!po=1.02041

What’s is going to take? How many more have to become infected before transmission studies on ALL implicated pathogens in Lyme/MSIDS are done?

We’ve known about Lyme for over 40 years and we still don’t have good studies looking at this very real issue of sexual and congenital transmission.  Only one study on sexual transmission done in 2014 showed the Lyme organism in semen and vaginal secretions, but the medical world sniffed and rolled over in bed.  Nothing’s been done since.

Why?

As to congenital transmission (mother to baby), Canada recognizes it, but the U.S. still doesn’t: https://madisonarealymesupportgroup.com/2018/10/05/canada-acknowledges-maternal-fetal-transmission-of-lyme-disease/  There’s 33 years of documentation gathered by a ticked off Canadian mom who happens to be a nurse: https://madisonarealymesupportgroup.com/2018/06/19/33-years-of-documentation-of-maternal-child-transmission-of-lyme-disease-and-congenital-lyme-borreliosis-a-review/

I guess more moms have to get ticked off before something changes in Lyme-land. Frankly, if it weren’t for moms, we wouldn’t even know Lyme exists.

We need these transmission studies done on each and EVERY single organism implicated with Lyme/MSIDS.  We can talk tick prevention all the day long until we are blue in the face, but what if you can contract Lyme/MSIDS through a variety of means? Many say we can:  https://madisonarealymesupportgroup.com/2019/04/02/transmission-of-lyme-disease-lida-mattman-phd/

But what do I know?  I’m just a crazy gray-hair.

More on Bartonella:  https://madisonarealymesupportgroup.com/2016/01/03/bartonella-treatment/

https://madisonarealymesupportgroup.com/2019/04/24/human-bartonellosis-an-underappreciated-public-health-problem/

https://madisonarealymesupportgroup.com/2019/03/24/cat-scratch-disease-caused-teens-schizophrenia-like-symptoms-report-says/

https://madisonarealymesupportgroup.com/2019/04/08/case-series-bartonella-ocular-manifestations/

https://madisonarealymesupportgroup.com/2019/03/02/skin-inflammation-nodules-letting-the-cat-out-of-the-bag/

https://madisonarealymesupportgroup.com/2019/01/02/bartonella-langerhans-cell-histiocytosis-cancer/

https://madisonarealymesupportgroup.com/2018/11/10/neurological-presentations-of-bartonella-henselae-infection/

https://madisonarealymesupportgroup.com/2017/01/04/endocarditis-consider-bartonella/