Archive for the ‘Inflammation’ Category

Lyme & Herxheimer Reactions – Dr. Rawls

https://rawlsmd.com/health-articles/lyme-herxheimer-reactions-your-guide-to-feeling-good-again?

lyme-disease-and-herxiemer-reactions

Lyme + Herxheimer Reactions: Your Guide To Feeling Good Again

by Carin Gorrell & Dr. Bill Rawls
Updated 1/21/19

It’s one of life’s cruel jokes: You discover a new therapy for Lyme disease and are really optimistic about your odds of finally feeling better. Then, within a day or two of starting the regimen, your symptoms take a turn for the worse—intense fatigue washes over you, and you feel like you did during your last fight with the flu. Could it be the dreaded Herxheimer Reaction you keep hearing about from fellow Lyme sufferers?

Unfortunately, answering that question is no easy feat. So we asked Dr. Bill Rawls, author of the bestselling book Unlocking Lyme, to help explain Herx Reactions and the best ways to differentiate them from other possible issues. Keep reading for his advice, plus steps you can take now to feel better—without derailing your recovery.

Herxheimer Reactions, Defined

Herxing was first observed in syphilis patients by dermatologists Adolf Jarisch and Karl Herxheimer in the late 1800s and early 1900s, who noticed that sufferers receiving treatment often got worse before they got better. The phenomenon was dubbed the Jarisch-Herxheimer Reaction, and has since been shortened to Herxheimer Reaction or simply, herxing.

“The classic explanation of a Herxheimer Reaction in Lyme sufferers is that when Borrelia bacteria are killed off by an antibiotic or herbal therapy, parts of dead bacteria called endotoxins are shed,” explains Dr. Rawls. “These endotoxins then circulate throughout the body and cause an intense whole-body inflammatory reaction. And that makes the war against microbes that’s already going on inside your body worse.”

In general, Herx Reactions are more common and more intense with conventional antibiotic use than with use of herbs, says Dr. Rawls. “With herbs, the bacterial die‐off is more gradual and the immune response is less intense.”

Either way, the intensification of your symptoms can be disconcerting, and if you’re treating Lyme, the odds are good you’ll experience herxing: While there’s no clinical research on the prevalence of herxing, anecdotally it seems the majority of Lyme sufferers experience it at some point. And that’s actually good news: “It’s often a sign that the therapy is working,” says Dr. Rawls.

How To Tell If It’s Herxing—Or Something Else

Herx Reactions can feel like a red herring, for a few reasons.

For starters, symptoms vary from person to person, says Dr. Rawls, and they’re easy to confuse with other health concerns that are also highly likely in chronic Lyme sufferers, including a disease flare-up, adverse reaction to a new Lyme treatment, or food sensitivity (digestive issues are highly common in Lyme sufferers). What’s more, the timing of any of these issues can also overlap, making it difficult to track your symptoms to their source.

For help clearing up the confusion and determining what’s to blame for your symptoms, check out these helpful identifying characteristics from Dr. Rawls:

HERX REACTION

Symptoms: Intensified fatigue, muscle pain, and flu‐like symptoms such as headache, nausea, GI distress. You may also experience symptoms not listed here; Herx Reactions are highly variable between individuals.

Onset: Symptoms intensify in tandem with starting a new therapy.

Telltale signs: Symptoms may gradually improve with continuation of therapy, and worsen again when you increase the dosage or add a new therapy.

LYME FLARE-UP

Symptoms: Intensification of fatigue, arthritis (joint pain, swelling, and stiffness), flu-like feelings, GI distress, recurrence of your usual Lyme symptoms

Onset: Symptoms are often precipitated by any type of extra stress to your system (including emotional stress, poor diet, toxin exposure, physical stress, lack of sleep, or a new tick bite). Symptoms are not related to starting a new therapy, though the two may coincide if you experienced stress just before starting the therapy.

Telltale signs: Your best clue is timing: A Lyme relapse typically occurs while taking a stable dose of treatment and in reaction to some type of stress, so look for recent lifestyle changes (i.e., diet changes, travel, sleep deprivation, relationships trouble).

ADVERSE TREATMENT REACTION

Symptoms: An allergic-like reaction (hives, itching, skin rash, runny nose, watery eyes, wheezing). This is common in people with chronic Lyme disease, whose entire immune system is in disarray and more easily activated.

Onset: Symptoms develop within about an hour of taking a new medication or herb

Telltale signs: Your symptoms get better when you take an allergy remedy such as an antihistamine. *See your doctor as soon as possible if you experience signs or symptoms of a drug allergy. Call 911 if you experience signs of a severe reaction or suspect an anaphylaxis after taking a medication.

FOOD SENSITIVITY

Symptoms: Fatigue, joint pain, muscle pain, general achiness, brain fog, irritability

Onset: Symptoms occur within hours to a couple of days after an offending food is consumed.

Telltale signs: Your symptoms get better when you eliminate the food(s) from your diet. Doctors can order testing for food sensitivity and heavy metal toxicity, however the best determinant of food sensitivities is an elimination diet.

If these guidelines don’t describe your experience with herxing exactly, take heart. In the beginning, you may go back and forth between knowing whether what you’re experiencing is Herx Reaction or something else, but with time, you will become better at distinguishing herxing and riding it out.

It’s Herxing. When Will It End?

If you’ve determined (or strongly suspect) that you’re herxing, your next question is likely: How long will it last?

Unfortunately, there’s no cut-and-dry answer — everyone’s experience is individual, says Dr. Rawls. Some may feel better after a few days or a few weeks; others may experience herxing for as long as two to three months (though symptoms tend to wax and wane throughout that time).

The good news is, there’s a lot you can do to help ease a Herx Reaction and move beyond the symptoms more quickly. The quickest solution would be to discontinue your Lyme treatment. But that’s not necessarily the best solution, says Dr. Rawls.

“Fundamental advice with herx is to continue therapy at whatever dose you can tolerate. Sometimes you will have to reduce the dose to stay comfortable, but you can increase again later” says Dr. Rawls. “If your symptoms improve over days to a couple of weeks, that suggests confirmation that it’s a herx.And as your symptoms improve, you can gradually increase the dose until the desired therapeutic dose is reached.”

If your symptoms do not improve, it may be an indication that the therapy is not working. In this case, Dr. Rawls suggests either increasing the dose or adding other herbs or other therapy. If symptoms gradually start getting better, then you know you’re on the right track.

That said, if your symptoms are debilitating, back off on your treatment dosage or even stop altogether, advises Dr. Rawls. Then, once your symptoms are tolerable, you can gradually increase your dosage again.

Smart Ways to Ease Herxing

The number one way to find relief from herxing is to address the underlying cause for needing Lyme treatment in the first place: chronic immune dysfunction.

“An impaired immune system is what makes people vulnerable to chronic Lyme,” explains Dr. Rawls. “Restore your immune function, and not only will your body be better at battling Lyme microbes, it’ll be stronger at withstanding the side effects of treatment and overcoming herxing as well.”

To begin, work your way through what Dr. Rawls calls System Disruptors, factors that can contribute to inflammation and intensify either a Herx reaction or a Lyme relapse. These include poor nutrition, emotional stress, environmental toxins like air pollutants and mold, physical stress, and excessive exposure to radiation from modern sources like computers, cell phones, and microwave towers.

Once you’ve begun to take the pressure off of your immune system by decreasing your exposure to these disruptors, your body will be better equipped to handle both microbes and the endotoxins they create as they begin to die off. The result: You start to feel better.

From here, there are a number of additional lifestyle habits you can adopt to help alleviate a Herxheimer Reaction—all of which also contribute to restoring immune function and thus contribute to Lyme recovery, says Dr. Rawls. Here, his recommendations:

1. Hydrate with fresh ginger tea.

A lot of liquids in general is a good idea, but fresh ginger tea in particular has potent systemic anti-inflammatory properties for reducing Herxheimer symptoms.

2. Add some natural therapies to your regimen.

Some good ones to try:

  • Turmeric and Boswellia They’re excellent for reducing systemic inflammation associated with Herxheimer reactions, and it’s hard to take too much of either. Dr. Rawls recommends 175 mg of turmeric and 75 mg of Boswellia, twice a day for each.
  • Marine source omega-3 fatty acids They offer anti-inflammatory support, especially for high-fat tissues such as the brain. Both fish oil and krill oil reduce inflammation, but krill is better absorbed and also contains the antioxidant astaxanthin, which provides extra anti-inflammatory support. The suggested dose for krill oil is 500 mg, 1-3 times daily.
  • Red Root This herb is very good for stimulating clearing dead cellular debris from the lymphatic system. It also supports a healthy liver and spleen, optimal immune function, and swollen lymph nodes.
  • Chlorella Consistently taking this freshwater algae does wonders for healing an irritated stomach and restoring digestive function. It’s also great for detoxing and healing in general. The typical maintenance dose is 5 to 7.5g total a day. For additional support, we suggest 10g total a day. Chlorella can be taken any time of day. For best results, take with food. (Avoid products that also contain spirulina, a blue-green algae that potentially contains toxins.)
  • Adaptogenic herbs. These help reduce herxing and moderate the effects of stress. Some to try: Chinese skullcap (450 mg, twice a day), Cordyceps(450 mg, twice a day), Reishi mushroom (175 mg, twice a day), and Rehmannia (50 mg, twice a day).

3. Take enzymes.

There are a variety that will work to help break down immune complexes and reduce inflammation. Bromelain (from pineapple) is a good choice; the dose is 500-1000 mg, one to two times daily. It’s sometimes found in combination supplements for joint health. In general, it’s best to take enzymes on an empty stomach so they are absorbed directly.

4. Apply heat.

Heat can be very soothing during Herx reactions. A far infrared (FIR) sauna and/or a hot bath are excellent for removing toxins from the body. Adding Epsom salts to your bath can also help soothe muscles and joints.

5. Get outside and breathe fresh air.

Forests and beaches or shores alongside open water are especially beneficial. Take your shoes off and walk barefoot: called “grounding,” it’s a good practice for reducing inflammation in the body.

6. Relax.

Decreasing stress is key to normalizing the body’s adrenaline/cortisol response. Some ideas:

  • Meditate
  • Get a massage, or try abhyanga (the Ayurvedic practice of self-massage)
  • Practice Qigong or yoga
  • Try acupuncture or energy healing

7. Sleep.

Make 7-8 hours of shuteye a nightly goal.

8. Say “no” more often.

Only agree to doing what’s necessary, and let the rest go until you are back on your feet.

9. Avoid coffee and green and black tea.

They tend to dry and irritate the stomach lining.

10. Eat steamed cabbage.

It’s great for soothing an inflamed stomach.

11. Use lavender essential oil.

Research suggests it may be beneficial for easing insomnia, anxiety, stress, and postoperative pain. Apply it to the bottom of your feet before bed to help with sleep.

12. Laugh lots.

It raises your immune system and just makes you feel good.

Thoughts on Herx Prevention

There’s a decent chance that if you increase the dosage of your current treatment or introduce a new one to your Lyme regimen, the herxing may return. It’s not entirely avoidable, says Dr. Rawls, but there are steps you can take to help fend off and reduce symptoms.

A few days before you change up your therapy, Dr. Rawls recommends adding some turmeric and krill or fish oil to your daily routine; these help support a healthy immune response. He also suggests using calming essential oils such as lavender and frankincense to reduce your stress response.

And in general, the most successful approach to feeling your best is to focus on restoring healthy immune function. Do that, and you’ll rebound faster from herxing and most other maladies that may come your way.

Dr. Rawls is a physician who overcame Lyme disease through natural herbal therapy. You can learn more about Lyme disease and recovery in Dr. Rawls’ best-selling book, Unlocking Lyme. You can also learn about Dr. Rawls’ personal journey in overcoming Lyme disease and fibromyalgia in his popular blog post, My Chronic Lyme Journey.

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**Comment**

For those of you just starting treatment:  https://madisonarealymesupportgroup.com/2015/12/06/tips-for-newbies/

More on Herxing:  https://madisonarealymesupportgroup.com/2015/08/15/herxheimer-die-off-reaction-explained/

https://www.lymedisease.org/lymesci-herxing/

https://madisonarealymesupportgroup.com/2017/06/28/jarisch-herxheimer-a-review/

Enzymes:  https://madisonarealymesupportgroup.com/2016/04/22/systemic-enzymes/

https://madisonarealymesupportgroup.com/2018/03/05/how-proteolytic-enzymes-may-help-lyme-msids/

https://madisonarealymesupportgroup.com/2018/10/24/herbs-habits-to-revive-your-gut/

MSM – another detoxifier, gut support, & inflammation & pain reducer:  https://madisonarealymesupportgroup.com/2018/03/02/dmso-msm-for-lyme-msids/

One of the hardest things to understand about this complex disease(es) is that you feel a whole lot worse before you feel better and this can take considerable time.  Managing the herx is a challenging job.  Many find sauna’s to be of great help.

 

 

Acute Transverse Myelitis – A Clinical Manifestation of Lyme (That Nobody Has a Clue About Prevalence)

https://www.ncbi.nlm.nih.gov/pubmed/30622896

2018 Dec 29;15:e00479. doi: 10.1016/j.idcr.2018.e00479. eCollection 2019.

Acute transverse myelitis – A rare clinical manifestation of Lyme neuroborreliosis.

Abstract

Acute transverse myelitis (ATM) is a rare, potentially devastating neurological syndrome that has variety of causes, infectious being one of them. Lyme disease (LD) is the most common vector borne zoonosis in the United States (U.S.). While neurologic complications of LD are common, acute transverse myelitis is an exceedingly rare complication.

We present a case of a previously healthy 25-year-old man who presented with secondary erythema migrans, aseptic meningitis and clinical features of transverse myelitis including bilateral lower extremity motor and sensory deficits manifesting as weakness and numbness, urinary retention and constipation.

Despite negative serum antibodies against Borrelia burgdoferi, cerebrospinal fluid (CSF) was positive for Borrelia burgdorferi PCR.

Following treatment with methylprednisolone and ceftriaxone, he attained complete recovery apart from neurogenic bladder necessitating intermittent self-catheterization. We report rare manifestation of a common disease and emphasize the importance of considering LD in the differential diagnosis of acute transverse myelitis, particularly in residents of endemic areas.

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**Comment**

Nobody has a CLUE about how often anything is occurring in Lyme/MSIDS, when testing misses over half of all cases and folks are commonly misdiagnosed or undiagnosed for years.  Again, because words mean things, and research has been used against patients for over 40 years, a more accurate statement would be, “This is the first recorded case of ATM caused by Lyme Disease.”  And remember, just because something isn’t on record doesn’t mean it hasn’t happened.  Important distinction.

According to https://myelitis.org/living-with-myelitis/disease-information/afm/

The predominant presentation is weakness that may affect the limbs, face, oral or eye muscle. Weakness varies greatly ranging from subtle to very severe. AFM may result in total paralysis, partial paralysis, or weakness of just one limb. The combination of paralysis and how individuals present are widely variable. The limbs or muscle structures of individuals with AFM appear weak, flaccid, or limp and are not spastic as seen in classic cases of transverse myelitis. Since it is markedly the gray matter of the spinal cord that is inflamed in individuals with AFM, sensory, bowel and bladder functions can remain intact, however there are individuals that have both upper and lower motor neuron involvement.

The enterovirus (EV-D68) has been suspect in many of these cases however, it has not been definitively proven that it is this particular virus that has caused the paralysis,(1) although several cases of AFM occurred at around the same time as an outbreak of the EV-D68 virus.(2)

There has been a spike in AFM:  https://madisonarealymesupportgroup.com/2018/10/19/rise-in-acute-flaccid-myelitis-cases-and-the-link-to-vaccinations/

Within the above link, you will learn there are numerous theories on what causes AFM including viruses & vaccinations.  Lyme/MSIDS patients often have viral involvement, and reactivation of Lyme has been documented after vaccinations:  https://madisonarealymesupportgroup.com/2017/12/02/scottish-doctor-gives-insight-on-lyme-msids/, as well as Bartonella:  https://madisonarealymesupportgroup.com/2016/04/24/gardasil-and-bartonella/

https://madisonarealymesupportgroup.com/2016/11/07/connection-of-acute-flaccid-myelitis-and-vaccinations/  In this article, James Lyons Weiler states:

The US press has been pushing a view of acute flaccid paralysis as a mysterious condition of unknown etiology (unknown cause). Checking the scientific literature, however, tells us that AFP is most often Guillain Barre Syndrome (GBS), a condition that appears on the National Vaccine Injury Compensation Program as a “Table Condition” – i.e., one that the US HHS has no defense against when parents file in the NVICP for compensation for GBS as a vaccine injury in their children.  https://madisonarealymesupportgroup.com/2018/12/07/acute-flaccid-paralysis-is-most-often-guillain-barre-syndrome/

GBS is also often a player with Lyme/MSIDS:  https://madisonarealymesupportgroup.com/2019/01/09/transverse-myelitis-guillain-barre-associated-with-bartonella/

https://madisonarealymesupportgroup.com/2017/07/14/clinical-association-lyme-disease-and-guillain-barre/  In Dr. Waisbren’s book, Treatment of Chronic Lyme Disease, the majority of his 51 cases of chronic Lyme had high EBV titers.  He also states,

“As will be seen in other cases, the Epstein-Barr virus may be a candidate for a co-infection associated with LD.”  

Waisbren often treated this co-infected patients that had EBV with 1000mg of Valtrex three times a day with good success.  He also used gamma globulin (4cc twice a week).

So Lyme/MSIDS patients are at the top of the list for AFM for numerous reasons.  Personally, I had a MRI at one point due to the excruciating pain in my spine and occipital headaches.  This pain was unrelenting.  Borrelia burgdorferi (Bb) loves the brain and spinal column.  Many viruses hang out in the spine.  The MRI showed nothing abnormal and I was sent home with the same pain I came with.  While I believe proper antimicrobial treatment to be imperative, what finally relieved this pain for me was MSM:  https://madisonarealymesupportgroup.com/2018/03/02/dmso-msm-for-lyme-msids/

Along with swelling in the spine, patients can have brain swelling as well.  Within one week, I met 3 Lyme patients with Chiari, another supposed “rare” condition:  https://madisonarealymesupportgroup.com/2016/04/02/chiari/  While Chiari is often caused by structural defects in the brain and spinal cord that occur during fetal development, it can also be caused due to injury, exposure to harmful substances, or infection. 

When you study the Bb organism, along with the numerous coinfections, spine and brain swelling makes complete sense and needs to be studied further:  https://madisonarealymesupportgroup.com/2016/02/13/lyme-disease-treatment/

There is so much research begging to be done, yet main stream medicine wants to wrap Lyme into a pretty box with a bow on top.  Again, if there is any box involved with Lyme/MSIDS, it’s Pandora’s.

 

 

LDN & CBD

 Approx. 1 Min

LDN Plus CBD

In this video Dr. Liptan explains the additive effects of CBD (cannabidiol) when taken with LDN (low dose naltrexone) in reducing neuroinflammation and fibromyalgia pain. CBD can also ease some of the side effects caused by LDN.

 

 Approx. 20 Min

CBD for Fibro Pt 1

Dr. Liptan explains the science of CBD, and its uses in the treatment of fibromyalgia. This video also covers:
  • The difference between THC and CBD
  • The effects of CBD on the body based on human and animal studies
  • CBD’s benefits for pain, muscle tension, arthritis, anxiety, insomnia, and adrenal fatigue

To purchase Dr. Liptan’s medical grade, lab tested CBD products visit https://www.fridabotanicals.com Dr. Liptan is also an author of:  “The FibroManual: A Complete Treatment Guide For You And Your Doctor” http://amzn.to/1XP7ZMV “The Fibro Food Formula” https://amzn.to/2rggeZt

**Comment**
I am not affiliated with any products nor do I make a red cent on anything related to this website or the support group; therefore, I can recommend the following product strictly from personal experience and use:  Lidtke CBD Gold:  https://lidtkecbd.com
We use the 2500mg plain.  While it’s $189.00, I only take 2-6 drops at night.  Definitely helps with sleep and pain.
cbd-gold-plain-2500mg
Their CBD Gold line of tinctures blends the full-spectrum CBD extract with supplements such as iodine, GABA, 5-HTP, L-tryptophan, and a whole-food complex of the vitamin C component. Besides, the Lidtke brand indicates that their manufacturing process is from non-GMO, herbicide and pesticide-free hemp for those seeking assurance on the possibility of additives.
We also take LDN.  You titrate up from 1.5mg.  Our ending dose is 4.5mg but some patients need higher dosages.  We found LDN helps our immune systems generally but specifically with better sleep and pain reduction.
Very informative documentary put out by the LDN Research Trust on Lyme/MSIDS.  Dr. Horowitz, Dr. Toups, Dr. Schweig, Dr. Windham, Dr. Holtorf, & Dr. Schwarzback, speak on everything from testing, to diet, to inflammation, and how LDN can help patients.

Your Liver is Your Detox Organ. Here’s Why & How to Support it

https://www.mindbodygreen.com/articles/support-liver-detox-with-supplements-and-herbs?

Your Liver Is Your Detox Organ. Here’s Why & How To Support It

Image by Marc Tran / Stocksy

We humans are alive because of brilliant biochemistry, and while each system of our body has its own unique function, they are all inextricably linked and work together to keep us alive and thriving. When one system goes awry, it often affects other seemingly unrelated aspects of our health. This is especially true when it comes to detox, which is one of the biggest factors of poor health that I see in my patients.

With research starting to show the link between our increased toxin exposure and autoimmune conditions, it’s more important than ever for your body’s detoxification systems to be working properly. As your body’s largest organ, your liver is also the main detoxifier.

Why your liver is your detox organ.

Working in constant communication with your stomach, pancreas, gallbladder, and the rest of your digestive system, your liver is responsible for storing and converting nutrients from the foods we eat for our bodies to utilize. Through its role in the metabolism of fat, protein, and carbohydrates, your liver works to ensure that blood glucose levels are stabilized to prevent blood sugar imbalances and other metabolic problems. It works to filter out toxins from the foods you eat and environmental exposures as well as acting as a blood purifier, clearing out your blood of these impurities and only utilizing the necessary nutrients. Needless to say, if your liver isn’t working well, your ability to detox is going to be greatly affected.

When your liver is overloaded with toxins, it creates a cascade of systemic chronic inflammation, which further affects your liver’s ability to rid itself of these toxins. It becomes a vicious cycle between toxin buildup and inflammation that can only be broken through limiting your toxin exposure and supporting your liver’s natural ability to detox.

Detox rituals that support your liver.

I’ve written in the past about various ways to make your life a cleanse. But to really boost your detox pathways and liver function, these targeted natural tools are my go-to for next-level liver and detox support:

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1. Dandelion tea

Methylation is your body’s biochemical superhighway that controls your body’s ability to detox. B vitamins act as fuel for methylation and are found abundantly in dandelions. Brew up a cup of dandelion tea to support methylation and help support optimal liver function.

2. Milk thistle

This plant is one of the most well-researched natural remedies for treating liver problems and has been used for years to treat a number of different liver conditions, including hepatitis and alcoholic liver disease. Milk thistle aids in eliminating toxins that have built up in the liver in addition to helping restore liver cells that have been damaged from increased toxin exposure. You can take it in a supplement capsule or as a tea.

Image by Yoyochow23 / iStock

3. Garlic

Garlic helps to activate liver detox enzymes that work to break down the toxins that enter your body in order to effectively eliminate them. Thankfully, garlic makes a delicious addition to almost any recipe, so don’t be afraid to load up while cooking your next meal!

4. Sulfuric vegetables

Vegetables such as broccoli, broccoli sprouts, mushrooms, Brussels sprouts, and cauliflower are considered sulfuric and contain the powerful antioxidant glutathione. This antioxidant is essential for activating phase 1 and phase 2 liver detoxification.

5. Beets

Beets are great for helping break down toxins through increasing enzyme activity so that your body can eliminate them quicker. I love roasting them as a side or adding them to a salad seasoned with garlic!

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6. Red clover

This is one of my favorites for its ability to rid toxins from not only your liver but your spleen and lymphatic system as well. You can take it in capsule form or as an herbal tincture.

7. Burdock root

As a tea or supplement, this root does wonders for removing toxins, specifically heavy metals. With its natural diuretic properties, it works to flush out toxins by increasing fluid excretion as well as boosting your lymphatic system.

You don’t have to adopt all these rituals to support your liver, but by making yourself a cup of dandelion tea, adding garlic and beets to your next meal, or taking a red clover supplement, you can support your detox pathways going into 2019.

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More on Detoxification:  https://madisonarealymesupportgroup.com/2018/02/24/top-3-lyme-detox-myths-busted-dr-rawls/

https://madisonarealymesupportgroup.com/2018/03/02/dmso-msm-for-lyme-msids/

https://madisonarealymesupportgroup.com/2018/01/03/the-invisible-universe-of-the-human-microbiome-msm/

Briefly, MSM stands for Methylsulfonylmethane and is 34% sulfur by weight. Sulfur plays a crucial role in detoxification and is an important antioxidant for producing glutathione. If you aren’t getting enough sulfur, glutathione can not work. Even if you have a diet rich in sulfur (think cabbage, onions, garlic, broccoli, etc – essentially the stinky veggies – and many other food items as well) your body still could use supplementation.

 

 

 

Bartonella & Langerhans’ Cell Histiocytosis (Cancer)

https://www.ncbi.nlm.nih.gov/pubmed/30556266

2018 Dec 17:e27573. doi: 10.1002/pbc.27573. [Epub ahead of print]

Disseminated Bartonella henselae disease mimicking Langerhans’ cell histiocytosis.

Abstract

Bartonella henselae, the causative agent of cat-scratch disease, has been recognized to be responsible for a broad range of clinical syndromes. We report the case of a patient with disseminated B. henselae infection mimicking Langerhans cell histiocytosis at presentation and its successful management with neurosurgery, prolonged antibacterial therapy, and observation.

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**Comment**

Langerhans’ cell histiocytosis is a supposed “rare” disorder that looks like cancer (some say it is cancer).  The above case study implicates Bartonella.

Bartonella is known to cause granulomas

https://madisonarealymesupportgroup.com/2018/09/06/ocular-manifestations-of-bartonellosis/  Bartonella spp. infections continue to be a common cause uveitis with ophthalmic manifestations ranging from neuroretinits, vascular occlusions, to choroidal granulomas.

Blausen.com staff (2014). “Medical gallery of Blausen Medical 2014”. WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN 2002-4436. – Own work, CC BY 3.0, https://commons.wikimedia.org/w/index.php?curid=29025014

The choroid is the vascular layer of the eye, containing connective tissues, and lying between the retina and the sclera.

https://madisonarealymesupportgroup.com/2018/03/04/bartonella-erythema-nodosum-atypical-presentations/  The finding of bilateral enlarged axillary lymph nodes with necrosis and granulomas led to the diagnosis of Bartonella infection, an unusual cause of erythema nodosum.

Granulomas represents a chronic inflammatory response initiated by various infectious and noninfectious agents.  https://medical-dictionary.thefreedictionary.com/granuloma

Langerhans cell histiocytosis is a type of eosinophilic granuloma

https://ghr.nlm.nih.gov/condition/langerhans-cell-histiocytosis  Excerpt below:

Langerhans cell histiocytosis is a disorder in which excess immune system cells called Langerhans cells build up in the body. Langerhans cells, which help regulate the immune system, are normally found throughout the body, especially in the skin, lymph nodes, spleen, lungs, liver, and bone marrow. In Langerhans cell histiocytosis, excess immature Langerhans cells usually form tumors called granulomas. Many researchers now consider Langerhans cell histiocytosis to be a form of cancer, but this classification remains controversial.

In approximately 80 percent of affected individuals, one or more granulomas develop in the bones, causing pain and swelling. The granulomas, which usually occur in the skull or the long bones of the arms or legs, may cause the bone to fracture.

Granulomas also frequently occur in the skin, appearing as blisters, reddish bumps, or rashes which can be mild to severe. The pituitary gland may also be affected; this gland is located at the base of the brain and produces hormones that control many important body functions. Without hormone supplementation, affected individuals may experience delayed or absent puberty or an inability to have children (infertility). In addition, pituitary gland damage may result in the production of excessive amounts of urine (diabetes insipidus) and dysfunction of another gland called the thyroid. Thyroid dysfunction can affect the rate of chemical reactions in the body (metabolism), body temperature, skin and hair texture, and behavior.  In 15 to 20 percent of cases, Langerhans cell histiocytosis affects the lungs, liver, or blood-forming (hematopoietic) system; damage to these organs and tissues may be life-threatening.

Older names that were sometimes used for forms of Langerhans cell histiocytosis include eosinophilic granuloma, Hand-Schüller-Christian disease, and Letterer-Siwe disease.

More on Bartonella:  https://madisonarealymesupportgroup.com/2016/01/03/bartonella-treatment/

https://madisonarealymesupportgroup.com/2018/09/06/ocular-manifestations-of-bartonellosis/

https://madisonarealymesupportgroup.com/2017/01/04/endocarditis-consider-bartonella/

https://madisonarealymesupportgroup.com/2018/11/05/skull-infection-due-to-bartonella/

https://madisonarealymesupportgroup.com/2017/09/13/dr-fox-cat-scratch-fever-warning/

https://madisonarealymesupportgroup.com/2016/11/29/bartonella-seizures/

https://madisonarealymesupportgroup.com/2018/11/10/neurological-presentations-of-bartonella-henselae-infection/

https://madisonarealymesupportgroup.com/2018/11/05/skull-infection-due-to-bartonella/