Archive for the ‘Anaplasmosis’ Category

Do You Still Need to Worry About Ticks in the Winter? (YES)

https://www.southernliving.com/are-ticks-dormant-in-winter

Do You Still Need To Worry About Ticks In The Winter?

Here’s what to know about these parasites.
A close-up shows a tick moving across light-colored pants,
Credit: Getty Images

You typically don’t encounter as many insects while you’re outdoors in winter as you do the rest of the year. But that doesn’t mean everything  that bites is hunkered down until spring. “Many tick species will have adults active during the winter months,” says Sonja L, Swiger, PhD, professor, medical entomologist and extension specialist with Texas A&M AgriLife. “Since ticks are blood feeders, they do quite well throughout the winter months because they are on a host.”

Of course, ticks don’t just bite; they also carry diseases that make people and pets sick. “The most commonly encountered tickborne pathogen in the Southeast is Rocky Mountain spotted fever,” says Swiger. But Lyme disease is also a threat, though it’s not transmitted at the same rate as it is in places such as the Northeast. Other diseases that ticks can pass to people and pets include ehrlichiosis and anaplasmosis.

In addition, if you think a cold or snowy winter will knock down ticks, that’s just wishful thinking. Harsh weather doesn’t really impact the tick population as a whole. “Ticks have been around for millions of years and are very good at what they do. They know how to survive,” says Eric Benson, PhD, professor emeritus and extension entomologist with  Clemson University. “During winter, many species of ticks go into diapause, a state when they reduce their metabolism to conserve energy to survive.”

 Here’s what else you should know about ticks in winter:  (See link for article)

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**Comment**

Great reminder to stay vigilant.

The article points out what this website has been publishing for years: ticks are marvelously ecoadaptive and will simply hide under leaf litter or snow when weather becomes harsh. This also proves that the climate and/or ‘climate change‘ has nothing to do with tick survival and disease propagation.  They are simply built to survive.  About the only thing they can’t handle is fire!

The article then lists ways to prevent tick bitesGo here for a multi-pronged approach.  Pet owners have nearly two times the risk of finding ticks, so multiple areas need to be addressed.

For more:

More on the ‘climate change’ agenda:

Lyme Disease Co-Infections: What You Need to Know

https://danielcameronmd.com/coinfections-backup/

Lyme Disease Loneliness
Jan31

Lyme Disease Co-infections: What You Need to Know

Lyme disease co-infections occur when a single tick bite transmits multiple pathogens. Up to 40% of Lyme patients in some regions also carry Babesia, Bartonella, Anaplasmosis, or Ehrlichia—yet these infections are frequently missed.

When co-infections go unrecognized, patients don’t fully recover. Standard Lyme treatment won’t clear a parasite like Babesia or intracellular bacteria like Anaplasmosis. Understanding lyme disease co-infections is essential for anyone who isn’t getting better despite treatment.


Why Co-infections Matter

Ticks don’t carry just one pathogen—they can harbor several at once. A single bite can transmit:

  1. Bacteria — Borrelia (Lyme), Anaplasma, Ehrlichia, Bartonella
  2. Parasites — Babesia species
  3. Viruses — Powassan, others

Co-infections typically make symptoms more severe, treatment more complicated, and recovery longer. Patients with multiple infections often experience symptoms that don’t fit neatly into one diagnosis—which leads to confusion, misdiagnosis, and delayed care.

If you’ve been treated for Lyme disease but still feel sick, a co-infection may be the reason.


Babesia

Babesia is a malaria-like parasite that infects red blood cells. It’s the most common Lyme disease co-infection in the Northeast and Midwest, with up to 40% of Lyme patients in some areas also testing positive.

Key symptoms:

  1. Drenching night sweats
  2. Air hunger (shortness of breath with normal oxygen)
  3. Profound fatigue beyond typical Lyme exhaustion
  4. Cycling fevers and chills

Why it’s missed: Standard Lyme antibiotics don’t work against Babesia. Patients improve on doxycycline, then relapse—because the parasite was never treated.

Treatment: Requires antiparasitic medications (typically atovaquone + azithromycin), not standard Lyme antibiotics.

Babesia Resources

→ Babesia and Lyme: What Patients Need to Know — Comprehensive guide with 57 articles covering symptoms, testing, treatment, and more.


Bartonella

Bartonella species cause several human diseases, most famously “cat scratch fever.” While traditionally associated with flea bites and cat scratches, Bartonella has been found in ticks—including black-legged ticks that transmit Lyme.

Key symptoms:

  1. Streak-like rash (in some patients)
  2. Swollen lymph nodes
  3. Neuropsychiatric symptoms — anxiety, irritability, rage
  4. Fatigue, headaches, fever

Why it’s missed: Testing is unreliable, and many physicians don’t consider tick-borne Bartonella. Psychiatric symptoms may be attributed to stress or mental illness rather than infection.

Related Reading: Bartonella

  1. Case Reports: Bartonella Associated with Psychiatric Symptoms
  2. ALS and MS Suspected in Woman Later Diagnosed with Bartonella and Lyme
  3. Babesia Bartonella: Neuropsychiatric Symptoms in Children

Anaplasmosis

Anaplasmosis (formerly Human Granulocytic Ehrlichiosis) is caused by the bacterium Anaplasma phagocytophilum. It’s transmitted by the same black-legged tick that carries Lyme disease.

Key symptoms:

  1. High fever, chills
  2. Severe headache
  3. Muscle aches
  4. Fatigue, malaise

Why it’s missed: Symptoms overlap with Lyme and other flu-like illnesses. Without specific testing, Anaplasmosis is often overlooked—especially when Lyme is already diagnosed.

Treatment: Responds to doxycycline, the same antibiotic used for Lyme. However, treatment duration and monitoring may differ when co-infection is present.

Related Reading: Anaplasmosis
  1. Babesia Anaplasmosis: Cognitive Impairment in Co-infection
  2. Tick Bite Multiple Co-infections: One Bite, Many Pathogens

Ehrlichia

Ehrlichiosis is caused primarily by Ehrlichia chaffeensis and transmitted by the Lone Star tick. It attacks white blood cells, potentially causing severe illness if untreated.

Key symptoms:

  1. Fever, headache
  2. Fatigue, muscle aches
  3. Nausea, vomiting
  4. Confusion (in severe cases)

Why it’s missed: Similar presentation to Anaplasmosis and other tick-borne diseases. Geographic distribution differs—Ehrlichiosis is more common in the Southeast and South-Central U.S.

Treatment: Doxycycline is the treatment of choice. Delayed treatment can lead to hospitalization.


Other Tick-Borne Infections

The list of tick-borne diseases continues to grow:

  1. STARI (Southern Tick-Associated Rash Illness) — EM-like rash from Lone Star tick, causative agent unknown
  2. Rocky Mountain Spotted Fever — Severe, potentially fatal if untreated
  3. Powassan Virus — Rare but serious neurological infection
  4. Borrelia miyamotoi — Relapsing fever-like illness
  5. Rickettsiosis — Various spotted fever group infections

When to Suspect Co-infections

Consider lyme disease co-infections if:

  1. Symptoms are unusually severe
  2. You’re not improving with standard Lyme treatment
  3. You relapse after completing antibiotics
  4. Night sweats, air hunger, or high fevers are prominent
  5. Neuropsychiatric symptoms don’t fit the typical Lyme pattern

Co-infections don’t always show up on tests. Clinical judgment—based on symptoms, exposure history, and treatment response—often guides diagnosis.


Frequently Asked Questions

Can you get multiple infections from one tick bite?

Yes. A single tick can carry several pathogens simultaneously, transmitting them all in one bite. This is why co-infections are so common in Lyme patients.

Why don’t standard Lyme antibiotics work for all co-infections?

Lyme disease is bacterial, but Babesia is a parasite—it requires antiparasitic medications. Bartonella may need different antibiotics than those used for Lyme. Each pathogen requires targeted treatment.

How are co-infections diagnosed?

Testing exists for most co-infections, but sensitivity varies. Blood smears, PCR, and antibody tests each have limitations. Clinical diagnosis based on symptoms is often necessary.

Do co-infections make Lyme disease worse?

Yes. Studies show that patients with co-infections experience more severe symptoms, longer illness duration, and slower recovery than those with Lyme alone.

What if I’ve been treated for Lyme but still feel sick?

Undiagnosed co-infection is one of the most common reasons for persistent symptoms after Lyme treatment. Evaluation for Babesia, Bartonella, and other pathogens should be considered.


Related Resources

  1. Babesia and Lyme: What Patients Need to Know — Complete Babesia hub
  2. Lyme Disease Symptoms
  3. Post-Treatment Lyme Disease Syndrome (PTLDS)
  4. Autonomic Dysfunction in Lyme Disease
  5. Lyme Disease Misconceptions

If you’re struggling with persistent symptoms despite Lyme treatment, co-infections may be part of the picture. Identifying and treating all tick-borne pathogens is often the key to recovery.

For more:

Case Report of Male With Anaplasmosis

https://www.cureus.com/articles/416304-relative-bradycardia-in-a-61-year-old-male-with-anaplasmosis-a-case-report#!/

Relative Bradycardia in a 61-Year-Old Male With Anaplasmosis: A Case Report

Jessica A. James • Melissa Brown • Samuel M. Segal • Maria Gutierrez-Castillo

Published: October 17, 2025

DOI: 10.7759/cureus.94785 

Peer-Reviewed

Cite this article as: James J A, Brown M, Segal S M, et al. (October 17, 2025) Relative Bradycardia in a 61-Year-Old Male With Anaplasmosis: A Case Report. Cureus 17(10): e94785. doi:10.7759/cureus.94785

Abstract

Human granulocytic anaplasmosis (HGA), or anaplasmosis, is a tick-borne illness caused by Anaplasma phagocytophilum, a gram-negative intracellular bacterium. A. phagocytophilum is primarily transmitted by Ixodes scapularis in the northeast United States and by Ixodes pacificus in California. Presenting symptoms typically include fever, chills, malaise, headache, myalgia, and rarely a rash. This case describes a 61-year-old Black male with a complex medical history, including prior tick-borne and arboviral infections (Lyme disease, dengue fever, and chikungunya), hypertension, mixed hyperlipidemia, bilateral carotid artery dissection, gastroesophageal reflux disease, atrial fibrillation with rapid ventricular response, and current tobacco use. This patient presented to an emergency department in upstate New York with a fever, fatigue, constipation, myalgia, and night sweats. Throughout the patient’s hospital course, he maintained a state of relative bradycardia. The patient reported that he had returned from Haiti and the Dominican Republic two weeks prior to presentation in the emergency department and received several mosquito bites while abroad. Initial guideline-based empiric treatment was started with doxycycline due to suspicion of tick-borne illness, given his history of Lyme disease and his onset of symptoms while in upstate New York. Treatment was continued to complete a 14-day course after confirming the diagnosis of anaplasmosis by PCR testing of whole blood. After completing treatment with doxycycline, the patient’s symptoms resolved completely. This case illustrates a unique finding of relative bradycardia and fever of unknown origin in the context of recent international travel and history of tick-borne and arboviral infections.

 

Babesia Rates Surge 9% in U.S. & 42% of Patients Are Coin-Infected

https://www.lymedisease.org/babesiosis-rates-surge-in-us/

Babesiosis rates surge by 9% annually in US; 42% of patients are co-infected

Penn State College of Medicine News

Oct. 8, 2024

Rates of babesiosis, a tick-borne parasitic disease, increased an average of 9% per year in the United States between 2015 and 2022.  And four in 10 patients were found to be co-infected with another tick-borne illness such as Lyme disease.

These were findings of a new study led by researchers at Penn State Health Milton S. Hershey Medical Center and Penn State College of Medicine.

“These findings suggest that clinicians should have a heightened vigilance of co-infection of other tick-borne illness among patients admitted with babesiosis,” said Paddy Ssentongo, infectious disease fellow, Penn State Health Milton S. Hershey Medical Center and lead author of the study.

“Ticks can carry other bacteria that cause Lyme disease and other tick-borne diseases like anaplasmosis and ehrlichiosis.”

They have published their findings in the journal Open Forum Infectious Diseases.

Babesiosis, sometimes referred to as “American malaria,” is caused by the Babesia parasite and is transmitted from bites of black-legged ticks. It’s found primarily in northeastern and midwestern states.

Similar to malaria

Like malaria, the parasite infects red blood cells, and the condition shares many similar clinical symptoms. According to the U.S. Centers for Disease Control and Prevention (CDC), although some people do not develop symptoms, others experience flu-like symptoms. The disease can be deadly for older adults and those with certain health conditions, such as a weakened immune system or lack of spleen.

“Understanding the drivers, dynamics and control of endemic and emerging vector-borne diseases is critical for global health interventions,” Ssentongo said.

The prevalence of babesiosis has been rising, according to the CDC. Ssentongo explained that climate change may play a role. Changing factors like temperature, humidity, rainfall and length of season have influenced the population and distribution of vectors like ticks as well as the population of animals that serve as reservoir hosts, like deer. As a result, ticks may be present in a wider geographical area.

The team set out to assess the current prevalence of babesiosis and Babesia co-infections as well as the effect of Babesia co-infection on mortality risk.

Using the TriNetX, a large, national database of clinical patient data from over 250 million individuals, they identified 3,521 individuals who were infected with babesiosis between October 2015 and December 2022.

Co-infections: Lyme, ehrlichiosis and anaplasmosis

The researchers found that the incidence of babesiosis increased an average of 9% per year. The majority of cases peaked during the summer months and were reported in northeastern states. Of those diagnosed with babesiosis, 42% were infected with one or more additional tick-borne diseases. That is a higher rate than what’s been found in previous studies.

The greatest percentage of those patients, 41%, were co-infected with the bacterium responsible for Lyme disease. A smaller portion of patients were co-infected with bacteria that cause ehrlichiosis and anaplasmosis, 3.7% and 0.3%, respectively.

When the team examined if co-infection amplified the risk of complications or led to worse outcomes, they found that there were no significant differences between the babesiosis-only group and the co-infection group. However, when they looked at mortality risk, they found that the risk of death was higher among the babesiosis-only group.

“Having both babesiosis and Lyme disease seemed not to be associated with worse mortality,” Ssentongo said, noting the finding was surprising. “It’s speculated that the concurrent presence of other tick-borne infections in the blood could alter the immune response by possibly ‘boosting’ it to effectively fight infections.”

The role of doxycycline

The difference in outcomes may also have to do with how other tick-borne illnesses are treated, Ssentongo said. In their study, the team found that the co-infection group was more likely to be prescribed doxycycline, the first line antibiotic treatment for Lyme disease, anaplasmosis and ehrlichiosis, compared to the babesiosis-only group. Ssentongo said that it raises a compelling question: Is doxycycline also effective in treating the Babesia parasite?

Currently, the treatment of babesiosis depends on disease severity. Treatment typically includes a combination of the antibiotics azithromycin and atovaquone. Red blood cell exchange, where abnormal red blood cells are removed and replaced by healthy ones, can also be considered for severely ill patients such as those with serious organ dysfunction. However, the survival benefit of red blood cell exchange hasn’t been studied extensively.

“For patients with babesiosis, we add on doxycycline as we’re investigating whether or not the patient has Lyme disease or other tick-borne diseases. We’ve seen better outcomes at our medical center with this approach,” Ssentongo said.

He said that there are other case reports where babesiosis has been successfully treated with doxycycline. However, more research is needed to understand the physiological pathways that underlie co-infection and how that might influence treatment protocols.

The most effective treatment approach is preventing tick-borne diseases in the first place, according to Ssentongo.

“If you live in areas where babesiosis is endemic, mostly states in the Northeast and the Midwest, take precautions, especially during the summer months,” Ssentongo said. “Practice tick-bite prevention practices. Wear long-sleeved shirts and pants and light-colored clothes. Use tick repellent and check for ticks after spending time outdoors.”

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For more:

NYC Ticks Found to Carry 5 Different Infections

https://www.lymedisease.org/nyc-ticks-found-to-carry-5-different-infections/

NYC ticks found to carry 5 different infections