Archive for April, 2021

Miami School Asks Staff NOT to Take COVID Jab; Global Media Assault Follows; Pfizer Trial May Support School’s Concerns

Miami School Asks Staff Not to Take COVID Jab; Global Media Assault Follows; Pfizer Trial May Support School’s Concern

© [4/29/21] GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC. Want to learn more from GreenMedInfo? Sign up for the newsletter here //www.greenmedinfo.com/greenmed/newsletter.”

Written By:  Sayer Ji, Founder
 

Centner Academy, a private school in Miami, has made international headlines for directing its employees who have not yet received the experimental COVID-19 vaccine, to wait until the end of the school year, as a precautionary step to protect the health of their school community, given both concerning new anecdotal reports that the vaccinated can adversely affect the health of the un-vaccinated, and that that clinical safety and efficacy data for the mRNA vaccines will not be completed until sometime in 2023.

Thus far, mainstream media reporting has focused and railed against the following statement made by Leila Centner, co-founder and CEO of Centner Academy, to her employees (in an internal email later leaked to the press) as being the most controversial and contestable: 

“Tens of thousands of women all over the world have recently been reporting adverse reproductive issues simply from being in close proximity with those who have received any one of the COVID-19 injections, e.g., irregular menses, bleeding, miscarriages, post-menopausal hemorrhaging, and amenorrhea (complete loss of menstruation).

No one knows exactly what may be causing these irregularities, but it appears that those who have received the injections may be transmitting something from their bodies to those with whom they come in contact. Until more is known, we must err on the side of caution when it comes to the welfare of our students and the school team.”

You can read Leila’s entire letter and comment which she posted to Instagram here.

Leila Centner’s private communication, now a matter of global public scrutiny, even reaching the White House press secretary for comment on April 27th,1 came under fire by a number of conventional allopathic physicians, including Dr. Aileen Marty, a physician and infectious disease specialist with Florida International University’s Wertheim College of Medicine, who commented as follows: 

“But there’s not one citation, there’s not one physician or scientist whose name is spelled out in there. There’s no references. There’s nothing. There is no scientific evidence provided. Rumor is the only thing that’s there, and if you look at the reality, there’s zero, zero science behind those allegations.” “If they believe it, and they then share this big lie, it has a horrific impact on our entire community,” she said.

While these comments by Dr. Marty, and now hundreds of other mainstream media reports have attempted to dismiss Leila Centner’s statements as a ‘source of misinformation, without basis in science,’ we believe they have significant merit, and are at the least worth exploring further. 

Fact #1: Vaccines Make Some Sick; Sick People Are More Likely to Compromise the Health of Others

Whereas the mainstream media and government health authorities have been dogmatically pushing the unequivocal narrative that the Covid-19 (and all) vaccines are “safe and effective” a priori, it is undeniable that the Covid-19 vaccines are presently only approved for distribution to the public under an Emergency Use Authorization, in lieu of proper clinical safety and efficacy trial data being available, and which are not estimated to be completed until April 2023 for the Pfizer vaccine.2

This makes Covid-19 vaccines, by definition, experimental, as Leila Centner has repeatedly offered as an explanation for her precautionary stance as to their unintended, adverse effects they may have to the health and well-being of her school staff, faculty, children and larger community.

Human medical experimentation, as defined by the Nuremberg code of medical ethics (1947), must not only be voluntary, but the participant needs to be fully informed of both the risks and benefits, in order to be able to give their full legal consent. Also, if the medical experimenter has reason to believe an intervention may cause harm, disability, or death he or she must suspend the experiment immediately.

In the case of the experimental mRNA Covid-19 vaccine rollouts, government data reveals the Covid-19 vaccines are having profound, adverse health effects on a subpopulation of recipients, as documented in the Vaccine Adverse Events Reporting System (VAERS), which as of April 28th, 2021, lists a total of 85,926 reports of the vaccinated experiencing adverse effects, ranging from death to hundreds of other symptoms and life-threatening conditions.  Moreover, VAERS is known to be highly ineffective in capturing the true extent of the actual number of vaccine adverse events, due to its highly passive, post-marketing surveillance methodology. Peer-reviewed research indicates that the rate of report capture is as low as 1% for thrombocytopenic purpura (low blood platelet related bleeding disorder) following the MMR vaccine and hypotonichyporesponsive (bluish skin; reduced consciousness) episodes following the DTP vaccine.3

The implication is that the actual scale of adverse effects within the vaccinated, which include immune dysregulation and suppression, may be several orders of magnitude higher than the already alarming scale of events reported through the conservative numbers offered by VAERS — which are almost universally ignored by the very same media attempting to discredit, defame, and make an example out of the Centner Academy.

Given that those who are experiencing immune dysfunction as a result of being vaccinated are more likely to express virus reactivation, such as a cluster of cases recently reported for vaccine-induced Herpes Zoster, or may also experience a disrupted microbiome leading the the overgrowth of opportunistic bacteria, fungi, virusess, i.e. so-called “pathogens,” the health risks to those around them may also increase significantly. It should be noted that this phenomenon of vaccine-induced adverse health effects is not solely associated with the Covid-19 or mRNA vaccines.

Greenmedinfo.com has a database of over 1300 studies indicating over 150 potential adverse health effects from vaccines presently in the CDC vaccine schedule. Therefore any vaccine could, in theory, weaken or disrupt the immune system of a vaccine recipient, increasing the likelihood that they may transmit infection or disease-provoking aspects of either their microbiome or cell contents (mediated via extracellular vesicles) to those around them, which will be explained in greater detail in section #3. 

Fact #2: The Pfizer mRNA Vaccine Clinical Trial Study Design Warns Against Proximity (Shared Air Inhalation or Skin Contact) Between Vaccine Participants and the Unvaccinated As A Possible Vectors of Harm

Titled, “A Phase 1/2/3 Study to Evaluate the Safety, Tolerability, Immunogenicity, and Efficacy of RNA Vaccine Candidates Against COVID-19 in Healthy Individuals,” the Pfizer Covid-19 mRNA vaccine study protocol document explicitly identifies in section 8.3.5. the need for monitoring what it calls “Exposure During Pregnancy or Breastfeeding, and Occupational Exposure.” A concern they take seriously enough that they require any incident to be reported within 24 hours to the Pfizer Safety system. 

According to the document an EDP [environmental exposure during pregnancy] occurs if, for example: “a male vaccine recipient exposes a female partner prior to or around the time of conception.”

Exposure to the study intervention is defined as “inhalation or skin contact,” indicating that physical proximity between the vaccinated and unvaccinated is recognized by the Pfizer study protocol to be a cause for concern for transmission of potential side effects of the vaccine.

The document also gives the following example of an EDP scenario: “A male family member or healthcare provider who has been exposed to the study intervention by inhalation or skin contact then exposes his female partner prior to or around the time of conception.” Clearly, in this case Pfizer is acknowledging that something as simple as a healthcare provider or family member who has been exposed to an mRNA vaccine recipient through “inhalation or skin contact” (i.e. physical proximity) could generate an adverse event and/or affect the study outcomes. 

Another example provided in section 8.3.5.2 titled, “Exposure During Breastfeeding,” gives the following example of what constitutes such an exposure: 

“ An example of environmental exposure during breastfeeding is a female family member or healthcare provider who reports that she is breastfeeding after having been exposed to the study intervention by inhalation or skin contact.”

Finally, in section 8.3.5.3., an “Occupational Exposure” occurs,

“when a person receives unplanned direct contact with the study intervention, which may or may not lead to the occurrence of an AE. Such persons may include healthcare providers, family members, and other roles that are involved in the trial participant’s care.” 

Clearly, the Pfizer mRNA vaccine protocol design reveals that concerns for how the vaccinated may adversely affect the health, and even reproductive outcomes, of the unvaccinated simply by being within physical proximity, are being taken extremely seriously by the manufacturer of the vaccine itself. In light of this, Leila Centner’s expressed concerns quoted at the beginning of this article are, in fact, backed by the most authoritative document we have on the experimental vaccine, and the nature of the human experiments being conducted on their behalf. So far, there has been no acknoweldgment or reporting on this fact by the global mainstream media, the vaccine manufacturers, nor government health authorities. It will be up to the reader to share this article, and get the word out. 

Fact #3: There is a Plausible Epigenetic Molecular Mechanism in Biology Whereby the Vaccinated May Affect the Health Status of the Unvaccinated  

The third major substantiating factor behind identifying the potential harm the vaccinated may have on the unvaccinated concerns the discovery of so-called horizontal information transfer within biological systems mediated by extracellular vesicles (EVs), which include a virus-like phenomenon known as microvessicle shedding and/or exosome-mediated transfer of nucleic acids. This falls within the category of epigenetics, which the apologists and shills for the mRNA vaccines’ purported safety and efficacy conveniently ignore in order to make their claim that was debunked in 1970 with the discovery of the enzyme reverse transcriptase. Reverse transcriptase is able to transcribe RNA to DNA, essentially destroying the fundamental dogma of molecular biology, namely, the undirectional flow of information from the cell nucleus to mRNA to protein can not be reversed. This dogma is still being used half-a-century later to make the false claim that the only health risk a genetically modified vaccine has worth discussing is the possibility that it may affect the structure or function of nuclear, protein-coding genes. We’ve even seen, through the discovery of exosomes, that the Weismann barrier has been penetrated, and somatic cells can communicate heritable information to the germline cells in what amounts to real-time, essentially devalidating the risk models presently used by vaccine manufacturers and regulators which do not account for the power epigenetic processes have to amplify the unintended adverse effects of genetically modified technologies and interventions. 

While mRNA vaccines are designed using genetically modified processes not dependent on live cell substrates, thereby precluding conventional problems with shedding associated with first generation vaccines like the MMR, it is possible that they do, in fact, contribute to microvessicle shedding,4 which represents an even greater, more persistent threat than live-cell vaccine shedding when it comes to the persistent biological impact the vaccinated can have on the un-vaccinated. Microvessicles, which range in size between 0.1–1.0 μm  are a type of extracellular vesicle (EVs), that are secreted by many different cell types within the body, both in times of health and disease, and are known to reflect the antigenic content of the cell of origin.5 They have stunningly similar characteristics to viruses.6  For instance, like SARS-COV-2, microvessicles have a lipid bilayer formed from the budding off from host cell membranes, and they can incorporate and reproduce aspects of a vaccinated or infected cells’ immunogenicity, such as including functional mRNA, viral proteins, and other nucleic acids capable of profoundly altering the structure and function of the cells to which they are transmitted. For instance, it is theoretically feasible that a vaccine recipient’s cells expressing COVID-19 spike protein as a result of transfection with mRNA from a Covid-19 vaccine may secrete microvesicles containing components “originally alien to the cell, such as proteins and nucleic acids that are transiently or constitutively expressed via plasmid or viral vector. “7  These microvessicles, like viruses, and other extracellular vessicles known as exosomes, can be transmitted to other individuals (inter-individual transmission) through both normal or diseased physiological processes.8 Extracellular exosomes have even been found to transfer nucleic acids cross kingdoms (plant > animal, fungal > bacterial), affecting the phenotypal expression of the target species. Therefore, it is plausible that microvessicles can transmit mRNA from a recently vaccinated individual to those within close proximity, and therefore could, in fact, “shed” mRNA and related biomolecules induced from the mRNA vaccination process to non-vaccinated individuals, inducing symptoms similar to those experienced by the vaccinated. Indeed, microvessicles may have a profound affect on the immune status of those who both produce them, and are exposed to them. A recent study concluded that research “strongly suggests that MVs may function as strong regulator of both innate and adaptive immune systems.”9 Microvessicles and exosomes have also been researched and developed as vaccine candidates, further indicating that they are already being looked at by the scientific community as potential vectors of immunogenicity and carriers of viral-like and disease-modulating if not also disease-promoting bio-information. 

Given the plausible mechanism through which a COVID-19 vaccine recipient’s body produces vaccine antigen (e.g. spike protein), and can package and transmit these antigens through viral-like microvessicles (and perhaps also exosomes) to others, Leila Centner’s statement “it appears that those who have received the injections may be transmitting something from their bodies to those with whom they come in contact,” has a plausible mechanism of action. Especially considering the afforementioned fact that Pfizer’s study protocol itself acknowledges that an unknown factor or mechanism may cause the unvaccinated to be adversely affected by the vaccinated. 

Either way, Leila Centner’s decision was made in the spirit of the precautionary principle, and her call for further investigation and information on the vaccines before proceeding with what amounts to a reckless human medical experimentation should not be identified as “fringe,” “irrational,” nor “crazy.” To the contrary, the medical establishment and would-be government regulators should themselves be raising the red flag over the tens of thousands of adverse effects that have already been reported to the government VAERS database.  

We live in a time and age where protecting our children from coerced and increasingly mandatory medical interventions that carry the risk of death and disability, is perhaps the most important advocacy of our lives. It takes great courage, conviction, and love to stand up and make a decision that is in the best interest of your community, and not your bottom line or public relations image. The Centner Academy’s prioritization of the precautionary principle, and Leila Center’s call for more research into the exploding number of adverse events that the mainstream media either ignores or actively covers up, is extremely honorable and worth everyone who follows our work and advocacy getting behind in support. 

Please support the Centner Academy through the following actions:
  1. Share this artcile with friends and family, in order to support our health freedom advocate, Leila Center, who is undergoing unprecedented media attack. 
  2. Do you have an experience to report of an adverse effect from the Covid-19 vaccines, or being exposed to someone who had it? 
  3. Support Instagram Leila Centner (send her some love). Comment here at Leila’s instagram account.
  4. Learn more about the incredibly positive philosophy of the Centner Academy, focusing on happiness as the centerpiece of a child’s success, and cultivating leaders with HEART.  

Also, please join us at www.StandforHealthFreedom.com, as we build a grassroots army of millions who believe in informed consent, parental rights, human and medical rights, for everyone. 

References

1 https://miami.cbslocal.com/2021/04/27/white-house-position-centner-academy-covid-vaccine/

2 https://fullfact.org/health/covid-19-vaccines/

3 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1615747/pdf/amjph00450-0108.pdf

4 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680703/

5 https://www.nature.com/articles/2404132

6 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233125/

7 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764926/

8 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816030/

9 https://www.frontiersin.org/articles/10.3389/fimmu.2018.02723/full

Sayer Ji is founder of Greenmedinfo.com, a reviewer at the International Journal of Human Nutrition and Functional Medicine,Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of the National Health Federation, Steering Committee Member of the Global Non-GMO Foundation.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of GreenMedInfo or its staff.

______________________

For more:

True to form, I woke up to this today.  It’s become quite obvious there are hired spin-doctors who do nothing more than counter information that is inconvenient for them.  

If you read it in full, they completely ignore the fact Pfizer mRNA Vaccine Clinical Trial Study Design Warns against proximity (Shared Air Inhalation or Skin Contact) between vaccine participants and the unvaccinated as a possible vectors of harm.  

Oop!s – that just doesn’t fit the accepted narrative so it must be avoided at all costs.  Instead, the article zeros in on “vaccine shedding” which doctors have already stated may not be the issue, but that somehow “vaccinated” people are transmitting something to the unvaccinated.  People are experiencing this and doctors are seeing it with their own eyes.

But similarly to Lyme/MSIDS, patient and doctor experience in reality just doesn’t matter to these people.  They will deny, deny, deny what is right in front of their faces.  We have experienced this for over 40 years in Lyme-land.  

Words and definitions matter, and the spin-doctors are busy at work to suppress/deny/malign anything that detracts from these experimental, fast-tracked injections that do not have historical data behind them, except for previous animal studies in which EVERY SINGLE ANIMAL DIED of ADE.

Category:

Activism, vaccines, Viruses

Doctor Defends ’80 Clinical Studies’ Showing Ivermectin ‘89% Effective’ At Preventing COVID

https://www.lifesitenews.com/news/doctor-defends-80-clinical-studies-showing-ivermectin-89-effective-at-preventing-covid

Doctor defends ‘80 clinical studies’ showing ivermectin ‘89% effective’ at preventing COVID

‘People are trying to scare us from taking ivermectin,’ Dr. Benigno Agbayani declared. ‘It’s one of the safest drugs in the world.’
Thu Apr 29, 2021 
Featured Image
Dr. Benigno Agbayani

By Michael Haynes

QUEZON, Philippines, April 29, 2021 (LifeSiteNews) — A doctor from the Philippines strongly defended the use of ivermectin for preventing and treating COVID-19, pointing to “80 clinical studies” which support his arguments, and alluding to “bias” and conflicts of interest, which have led medical bodies to be reluctant about promoting the drug.

Appearing on Philippine television channel ABS–CBN, Dr. Benigno Agbayani answered a range of questions about the efficacy and safety of the drug, as well as the peculiar reticence to recommend it for treating COVID-19.

Agbayani, the president of Concerned Doctors and Citizens of the Philippines, revealed that since last year, he had spent over five hours a day studying scientific literature on all things pertaining to COVID-19, including the non-effectiveness of lockdowns. “I think I’ve read more than anyone on COVID-19,” he stated. (See link for article)

______________________

**Comment**

Agbayani has successfully used ivermectin in over 300 of his own patients.

Important excerpts:

“As much as anecdotal [pieces of evidence] are good, and we have many, I really prefer that we stick to the science,” he said. “People are trying to scare us from taking ivermectin. It’s one of the safest drugs in the world.”

Mentioning a study from September 2020, Agbayani stated that ivermectin had been shown to actually block “the receptor sites of the virus onto our cells, therefore blocking it from ever getting to the cell.”

“You have over 26, as of today, randomized control trials showing effectiveness, even as high as 89% for prevention, and as high as 80% for treatment. So I think regardless of what the other groups are doing, you have so much science behind it, I do not see why we have to be so concerned.”

He alluded to the peculiar antagonism which has been levied against ivermectin, noting how scepticism regarding studies promoting ivermectin is not mirrored with other drugs: “[T]he same thing can be said of every drug that we tried. Even people who are taking remdesevir, they also try other drugs, and yet you don’t question that.”

The article points out that medical bodies are still resistant to the use of ivermectin with with Big Tech even weighing in and deleting videos which defends the drug. Thanks to the efforts of the Front Line Covid-19 Critical Care Alliance (FLCCC), the U.S. National Institutes of Health (NIH) upgraded their recommendation for the “miraculous” drug ivermectin, making it an option for use in treating COVID-19 within the United States, but only since January.

Agbayani states there is a clear bias and that ‘authorities’ do not want to look at certain studies:

“There is some kind of bias going on that we’d like to question. This is the time in our history when we should look at conflicts of interest.” Dr. Benigno Agbayani

The vaccine company Merck even issued a statement advising against the use of ivermectin for COVID, despite having developed it some 30 years prior. This was an “excellent example of conflict of interest,” stated Agbayani.

Evidently Merck is coming out with a NEW drug for COVID-19 – which means they will not make money off of it if ivermectin is the drug of choice.

Regarding safety, Agbayani states it has a 25-year safety record and that you could take ten times the NIH daily recommended amount and it would not yield side effects.

The article thankfully mentions Dr. Pierre Kory’s address to the Senate, which was censored by Youtube, defending ivermectin as well as the following quote:

“It literally destroys the virus in most people within 48 hours,” agreed fellow panelist Dr. Jean-Jacques Rajter, whose peer-reviewed study found 60% fewer deaths among patients given the drug.

Research done last year in Australia showed that a SINGLE dose could kill COVID-19 in a petri dish within 48 hours, and that after just 24 hours there was significant reduction of the virus.

I’ve written about our experience using ivermectin for COVID-19 here.  (Scroll to comment section) I must state our experience mirrors the research presented within this article that that we both felt significant relief within 24 hours and miraculous relief within 48 hours.  I freely admit that both IV C and blood ozone are also effective against viruses – which I also used.  My husband; however, only used blood ozone and ivermectin and had the same results as I.

The censorship of effective, lifesaving treatments should be a crime.  If it wasn’t for the efforts by many doctors and health practitioners defending ivermectin, and other effective treatments, they would have been completely bypassed for lucrative yet ineffective drugs like Remdesivir, which many of our public ‘authorities’ have a vested interest in, and obtain monies from its sale.  They had hoped to regain lost profits from this drug which also failed in the past.

Also, government-funded research on another effective treatment had to be retracted due to a fraudulent research.  And the misinformation continues to flow.
Until these conflicts of interest are addressed, we will never be told the truth.

Category:

Treatment, Viruses

They Shall Not Be Left to Rot: The Emerging Law of Lyme Disease

https://www.belmontlawreview.org/articles/volume-8-issue-1-2020/

transparent-law-logo-retina

VOLUME 8, ISSUE 1: 2020

Creighton R. Meland, Jr.

They Shall Not Be Left to Rot: The Emerging Law of Lyme Disease

For the excellently written paper for the Belmont Law Review, on the state of affairs with Lyme disease, please see this pdf:  https://cpb-us-w2.wpmucdn.com/blogs.belmont.edu/dist/8/25/files/2020/11/Meland_95-163.pdf

Table of Contents:

INTRODUCTION 96

I. WHAT IS LYME DISEASE AND WHY IS IT MEDICALLY CONTROVERSIAL? 97

     A. What is Lyme Disease? 97

     B. Lyme Disease Detection and Diagnosis 101

     C. Lyme Disease Treatment Regimens 104

          1. IDSA v. ILADS 104

          2. Coinfections and their Effect on Treatment 106

     D. Lyme Disease is not a Research Priority 107

II. LYME DISEASE LEGAL ISSUES 108

     A. IDSA and CDC Set Treatment Standards 108

          1. Effects on Quality and Availability of Care 108

          2. Antitrust Implications 112

     B. State Lyme Disease Legislation 122

          1. Health Insurance Coverage Mandates 122

          2. Professional Standards 125

          3. Lyme Testing Disclosures 127

          4. Safe Harbors 130

          5. Awareness, Prevention, and Government Support 133

**J.D. University of Michigan; B.S. Economics, Major in Finance, Wharton School, Undergraduate Division, University of Pennsylvania.**

I am grateful to Belmont Law Review for the opportunity to critique laws designed to redress health care problems presented by Lyme disease. Despite a pervasive presence and severe symptoms, Lyme disease is widely misunderstood by the medical community and too often goes untreated or improperly treated. While we await advances in medical science, the law can help those who suffer. I recognize and thank the International Lyme and Associated Diseases Society and its many contributors, who have deepened my understanding of medical problems associated with Lyme disease.  These insights have influenced positively the form of the work I now submit.

Category:

Activism, Lyme, Prevention, research, Testing, Treatment

Mushroom Power: Five Therapeutic Properties of Medicinal Mushrooms

https://www.greenmedinfo.com/blog/mushroom-power-five-therapeutic-properties-medicinal-mushrooms1?

Mushroom Power: Five Therapeutic Properties of Medicinal Mushrooms

Written By:

Dr. Diane Fulton

© 4/22/21] GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC. Want to learn more from GreenMedInfo? Sign up for the newsletter here:  //www.greenmedinfo.com/greenmed/newsletter.

Mushrooms have recently gained popularity in culinary circles, but their far-reaching therapeutic properties should get your attention for a longer and healthier life

Although mushrooms have been part of the healer’s toolbox since ancient times, the medicinal power of mushrooms is gaining momentum in evidence-based journals.

Medicinal mushrooms come in a wide variety and shapes such as white button, reishi, maitake, shiitake, oyster, cordyceps, cauliflower, tiger tail and lion’s mane, and most have health benefits that range from fighting cancer and boosting your immunity and memory to preventing diseases like diabetes and arthritis.

Five Therapeutic Properties of Mushrooms

1. Anticancer

Reishi (in Japanese) or lingzhi (in Chinese) mushrooms are well known in Asia for their anticancer properties. In a meta-analysis by scientists of 23 trials involving 4,246 cancer patients, reishi mushrooms enhanced longevity and quality of life in cancer patients.[i]

Therapy with white button mushrooms impacted prostate-specific antigen (PSA) levels and inhibited prostate cancer by decreasing immunosuppressive factors.[ii]

Polysaccharides from Cordyceps cicadae mushrooms inhibited the growth of cancer cells and induced cancer cell deaths showing its effectiveness as a low cost and safe treatment for cervical cancer.[iii]

A peptide from the shiitake mushroom showed promising results in growth arrest, cell death and cleaning out damaged cells in a breast cancer in vitro study.[iv] In both in vitro and in vivo studies, results showed that mice with induced testicular cancer treated with the Cordyceps sinensis mushroom had significantly smaller and fewer tumors than the control group.[v]

Cordyceps cicadae mushroom treatment prevented testicular damage and tumors caused by the chemotherapy drug cisplatin via inhibition of oxidative stress and inflammation in rats.[vi]

In a lung cancer-induced study of mice, treatment with reishi mushrooms inhibited cell viability and mobility of lung cancer cells in vitro.[vii] In a cell study of reishi mushroom extract, the treatment offered high antitumor and liver protection with low toxicity on human liver cancer cells.[viii]

2. Immunomodulatory

In a meta-analysis of 20 animal disease studies, grifola frondosa, or maitake mushroom, polysaccharide showed strong immune function by enhancing T cells, natural killer cells and macrophages in mice and increasing the secretion of two important immune factors, TNF-α and INF-γ.[ix]

In a clinical study of 105 cancer patients undergoing chemotherapy or radiation treatments, a combination of reishi mushroom extract and geraniums improved immunity and fought the cancer and secondary infections that could have compromised treatment and health.[x]

In a study of 18 patients diagnosed with low and intermediate myelodysplastic syndrome, which can lead to leukemia if not managed well, maitake mushroom extract treatment of three milligrams (mg) twice a day for 12 weeks increased immunity, positively affecting neutrophil, monocyte and free radical production.[xi]

In a clinical study of asymptomatic children from 3 to 5 years old, treatment with beta glucans from reishi mushrooms showed increased immune system cells in the peripheral blood — signaling a strong defense against childhood infections.[xii]

Reviewing in vivo and in vitro studies on mice and human cell lines using lion’s mane (Hericium erinaceus) and tiger tail (Trametes versicolor) mushrooms, treatments showed immunomodulatory, anticancer, anti-inflammatory and neuroregenerative effects.[xiii]

3. Antioxidant

Polysaccharide beta glucan extracted from reishi mushroom was shown to be a powerful antioxidant in 37 high risk and 34 stable angina patients; those who were treated with 750 mg per day for three months had significantly decreased oxidative radicals and improved progression of atherosclerosis.[xiv]

In a study of 42 healthy subjects, another intervention with beta glucan from reishi mushrooms of 225 mg per day for three months demonstrated its antioxidative effects — enhanced total antioxidant capacity and enzyme activities as well as reduced mild fatty liver condition to normal by suppressing oxidative stress were observed.[xv]

4. Anti-inflammatory 

Crohn’s disease is a chronic inflammatory disease of the gastrointestinal tract. Treatment with a triterpene compound from reishi mushrooms showed that the inflammatory cytokines were significantly inhibited in a study of children with Crohn’s disease.[xvi]

Sixty patients with moderate persistent asthma were studied and those who took the cordyceps sinensis mushroom capsule for two months had reduced airway inflammation caused by their chronic asthma.[xvii]Cordycepin from medicinal mushrooms showed strong effects on many anti-inflammatory diseases.[xviii]

In a study of 32 patients with active rheumatoid arthritis, supplementation of medicinal mushroom and Chinese herbs — reishi (4 grams) and San Miao San (2.4 grams) daily — lowered arthritic pain for patients.[xix] The data in a mice study support a model where white button mushrooms regulate immunity in vitro and protect the colon from inflammation-induced injuries in vivo.[xx]

The brain is susceptible to inflammation as well. In an Alzheimer’s disease model of rats, treatment with medicinal mushroom extracts delayed disease progression, improved learning and memory functions and stopped neural cell deaths and brain atrophy.[xxi]

Chaga mushrooms administered to mice successfully protected against Alzheimer’s disease by modulating oxidative stress, Nrf2 signaling and mitochondrial cell deaths while improving memory and cognition.[xxii]Cordycepin from the Cordyceps sinensis mushroom alleviated Parkinson’s disease motor disorder symptoms by lowering oxidative stress and inflammation in vivo and in vitro.[xxiii]

Lion’s mane mushrooms were supplemented for 12 weeks and were effective in preventing dementia and cognitive decline.[xxiv] Lion’s mane supplementation for four weeks in a study of 30 females also reduced depression and anxiety.[xxv]

5. Antidiabetic

Dyslipidemia, high blood cholesterol and triglycerides is often a harbinger of future diabetes. In a rat model, white button mushrooms and a probiotic were found to lower dyslipidemia and decrease oxidative stress.[xxvi] In a study of 89 diabetic patients, oyster mushroom consumption significantly reduced blood glucose, blood pressure, triglycerides and cholesterol without ill effects on the liver or kidneys.[xxvii]

Polyphenols from Phellinus igniarius, or willow bracket, mushroom extract were used in vitro and in vivo studies of induced Type 2 diabetes mice and showed improved glucose tolerance, reduced hyperglycemia and normalized insulin levels.[xxviii]

Diabetic nephropathy, kidney disease caused by Type 2 diabetes, was studied in vitro with disease-induced rats and treatment with Cordyceps cicadae resulted in improved insulin resistance and glucose tolerance, suppressed inflammation and balanced gut microbiome thus stopping the diabetes-related progression of renal disease and tumors.[xxix]

In an animal study, maitake mushroom prevented the progression of kidney fibrosis in diabetic nephropathy rats, significantly decreased fasting blood glucose levels, reduced inflammatory cytokines and lowered renal fibrosis indexes indicating its effectiveness in the treatment or prevention of nephropathy.[xxx]

In their meta-analysis of 623 articles and 33 randomized controlled experiments using cauliflower mushroom extract (S. Crispa), researchers found statistically significant differences in diabetic symptoms including decreased serum insulin levels and wound rates and an increase in nutrient intake content.[xxxi]

Mushrooms and Their Medicinal Powers

Medicinal mushrooms are widely researched and used as treatment in the prevention and progression of many diseases from cancer and asthma to diabetes and dementia. Mushrooms protect you due to their anti-inflammatory, antitumor, antidiabetic, immune boosting and antioxidant activities. To learn more, see GreenMedInfo.com’s database on mushrooms.

References

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[ii] Przemyslaw Twardowski, Noriko Kanaya, Paul Frankel, Timothy Synold, Christopher Ruel, Sumanta K Pal, Maribel Junqueira, Manisha Prajapati, Tina Moore, Pamela Tryon, Shiuan Chen. A phase I trial of mushroom powder in patients with biochemically recurrent prostate cancer: Roles of cytokines and myeloid-derived suppressor cells for Agaricus bisporus-induced prostate-specific antigen responses. Cancer. 2015 Sep 1 ;121(17):2942-50. Epub 2015 May 18. PMID: 25989179

[iii] Jiao Xu, Zhi-Cheng Tan, Zhong-Yuan Shen, Xing-Jia Shen, Shun-Ming Tang. Cordyceps cicadae polysaccharides inhibit Human cervical cancer Hela cells proliferation via Apoptosis and Cell Cycle Arrest. Food Chem Toxicol. 2021 Jan 6:111971. Epub 2021 Jan 6. PMID: 33421460

[iv] Syed Riaz Ud Din, Mintao Zhong, Muhammad Azhar Nisar, Muhammad Zubair Saleem, Akbar Hussain, Kavish H Khinsar, Shahid Alam, Gohar Ayub, Sadia Kanwal, Xingyun Li, Wei Zhang, Xiaoli Wang, Anhong Ning, Jing Cao, Min Huang. Latcripin-7A, derivative of Lentinula edodes C, reduces migration and induces apoptosis, autophagy, and cell cycle arrest at Gphase in breast cancer cells. Appl Microbiol Biotechnol. 2020 Dec ;104(23):10165-10179. Epub 2020 Oct 12. PMID: 33044599

[v] Ming-Min Chang, Siou-Ying Hong, Shang-Hsun Yang, Chia-Ching Wu, Chia-Yih Wang, Bu-Miin Huang. Anti-Cancer Effect of Cordycepin on FGF9-Induced Testicular Tumorigenesis. Int J Mol Sci. 2020 Nov 6 ;21(21). Epub 2020 Nov 6. PMID: 33172093

[vi] Ling Wang, Yigang He, Yudi Li, Chengbin Pei, Opeyemi Joshua Olatunji, Jian Tang, Ademola C Famurewa, Hongyan Wang, Bei Yan. Protective Effects of Nucleosides-Rich Extract from Cordyceps cicadae against Cisplatin Induced Testicular Damage. Chem Biodivers. 2020 Nov ;17(11):e2000671. Epub 2020 Nov 3. PMID: 33007148

[vii] Wei-Hung Hsu, Wei-Lun Qiu, Shu-Ming Tsao, Ai-Jung Tseng, Mei-Kuang Lu, Wei-Jyun Hua, Hsin-Chung Cheng, Hsien-Yeh Hsu, Tung-Yi Lin. Effects of WSG, a polysaccharide from Ganoderma lucidum, on suppressing cell growth and mobility of lung cancer. Int J Biol Macromol. 2020 Oct 1. Epub 2020 Oct 1. PMID: 33011264

[viii] Liping Zhu, Min Wu, Peng Li, Yanfei Zhou, Jinyi Zhong, Zhiqiang Zhang, Ye Li, Weixi Yao, Jianhua Xu. High-Pressure Supercritical COExtracts ofFruiting Body and Their Anti-hepatoma Effect Associated With the Ras/Raf/MEK/ERK Signaling Pathway. Front Pharmacol. 2020 ;11:602702. Epub 2020 Dec 14. PMID: 33381043

[ix] Zhang T, Zhao F, Wu KN, Jia Y, Liao XL, Yang FW, Zhang JH, Ma B. Meta-analysis on effect of Grifola frondosa polysaccharide in regulating in vivo immunoregulatory function on animal disease models. Zhongguo Zhong Yao Za Zhi. 2019 Dec;44(23):5174-5183. Chinese. doi: 10.19540/j.cnki.cjcmm.20190823.401. PMID: 32237355.

[x] Zhuang SR, Chen SL, Tsai JH, Huang CC, Wu TC, Liu WS, Tseng HC, Lee HS, Huang MC, Shane GT, Yang CH, Shen YC, Yan YY, Wang CK. Effect of citronellol and the Chinese medical herb complex on cellular immunity of cancer patients receiving chemotherapy/radiotherapy. Phytother Res. 2009 Jun;23(6):785-90. doi: 10.1002/ptr.2623. PMID: 19145638.

[xi] Wesa KM, Cunningham-Rundles S, Klimek VM, Vertosick E, Coleton MI, Yeung KS, Lin H, Nimer S, Cassileth BR. Maitake mushroom extract in myelodysplastic syndromes (MDS): a phase II study. Cancer Immunol Immunother. 2015 Feb;64(2):237-47. doi: 10.1007/s00262-014-1628-6. Epub 2014 Oct 29. PMID: 25351719; PMCID: PMC4317517

[xii] Sandra Lorena Duque Henao, Sergio A Urrego, Andrea M Cano, Edwin A Higuita. Randomized Clinical Trial for the Evaluation of Immune Modulation by Yogurt Enriched withβ-Glucans from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), in Children from Medellin, Colombia. Int J Med Mushrooms. 2018 ;20(8):705-716. PMID: 30317947

[xiii] Mateusz Winder, Weronika Bulska-Będkowska, Jerzy Chudek. The use of Hericium erinaceus and Trametes versicolor extracts in supportive treatment in oncology. Acta Pharm. 2021 Mar 1 ;71(1):1-16. PMID: 32697746

[xiv] Djanggan Sargowo, Nadia Ovianti, Eliana Susilowati, Nizamuddin Ubaidillah, Adriyawan Widya Nugraha, Vitriyaturrida, Kartika Siwi Proboretno, Mirza Failasufi, Fadhli Ramadhan, Hesti Wulandari, Yoga Waranugraha, Dinarsari Hayuning Putri. The role of polysaccharide peptide of Ganoderma lucidum as a potent antioxidant against atherosclerosis in high risk and stable angina patients. Indian Heart J. 2018 Sep – Oct;70(5):608-614. Epub 2017 Dec 14. PMID: 30392496

[xv] Hui-Fang Chiu, Hui-Yu Fu, Yan-Ying Lu, Yi-Chun Han, You-Cheng Shen, Kamesh Venkatakrishnan, Oksana Golovinskaia, Chin-Kun Wang. Triterpenoids and polysaccharide peptides-enriched Ganoderma lucidum: a randomized, double-blind placebo-controlled crossover study of its antioxidation and hepatoprotective efficacy in healthy volunteers. Pharm Biol. 2017 Dec ;55(1):1041-1046. PMID: 28183232

[xvi] Changda Liu, David Dunkin, Joanne Lai, Ying Song, Clare Ceballos, Keith Benkov, Xiu-Min Li. Anti-inflammatory Effects of Ganoderma lucidum Triterpenoid in Human Crohn’s Disease Associated with Downregulation of NF-κB Signaling. Inflamm Bowel Dis. 2015 May 19. Epub 2015 May 19. PMID: 25993687

[xvii] Ning-qun Wang, Liang-duo Jiang, Xiao-mei Zhang, Zong-xin Li. Effect of dongchong xiacao capsule on airway inflammation of asthmatic patients. J Hypertens. 2005 Sep;23(9):1699-706. PMID: 17972591

[xviii] Tan L, Song X, Ren Y, Wang M, Guo C, Guo D, Gu Y, Li Y, Cao Z, Deng Y. Anti-inflammatory effects of cordycepin: A review. Phytother Res. 2020 Oct 8. doi: 10.1002/ptr.6890. Epub ahead of print. PMID: 33090621.

[xix] Edmund K Li, Lai-Shan Tam, Chun Kwok Wong, Wai Ching Li, Christopher W K Lam, Sissi Wachtel-Galor, Iris F Benzie, Yi Xi Bao, Ping Chung Leung, Brian Tomlinson. Safety and efficacy of Ganoderma lucidum (lingzhi) and San Miao San supplementation in patients with rheumatoid arthritis: a double-blind, randomized, placebo-controlled pilot trial. J Pediatr Gastroenterol Nutr. 2010 Feb;50(2):208-11. PMID: 17907228

[xx] Sanhong Yu, Veronika Weaver, Keith Martin, Margherita T Cantorna. The effects of whole mushrooms during inflammation. BMC Immunol. 2009;10:12. Epub 2009 Feb 20. PMID: 19232107

[xxi] Guoxiao Lai, Yinrui Guo, Diling Chen, Xiaocui Tang, Ou Shuai, Tianqiao Yong, Dongdong Wang, Chun Xiao, Gailian Zhou, Yizhen Xie, Burton B Yang, Qingping Wu. Alcohol Extracts FromDelay the Progress of Alzheimer’s Disease by Regulating DNA Methylation in Rodents. Front Pharmacol. 2019 ;10:272. Epub 2019 Mar 26. PMID: 30971923

[xxii] Yanqiu Han, Shanji Nan, Jia Fan, Qiuhui Chen, Yizhi Zhang. Inonotus obliquus polysaccharides protect against Alzheimer’s disease by regulating Nrf2 signaling and exerting antioxidative and antiapoptotic effects. Int J Biol Macromol. 2019 Mar 13 ;131:769-778. Epub 2019 Mar 13. PMID: 30878614

[xxiii] Chunyan Cheng, Xiaoying Zhu. Cordycepin mitigates MPTP-induced Parkinson’s disease through inhibiting TLR/NF-κB signaling pathway. Life Sci. 2019 Feb 18. Epub 2019 Feb 18. PMID: 30790609

[xxiv] Yuusuke Saitsu, Akemi Nishide, Kenji Kikushima, Kuniyoshi Shimizu, Koichiro Ohnuki. Improvement of cognitive functions by oral intake of Hericium erinaceus. Biomed Res. 2019 ;40(4):125-131. PMID: 31413233

[xxv] Nagano M, Shimizu K, Kondo R, Hayashi C, Sato D, Kitagawa K, Ohnuki K. Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake. Biomed Res. 2010 Aug;31(4):231-7. doi: 10.2220/biomedres.31.231. PMID: 20834180.

[xxvi] Farhan Asad, Haseeb Anwar, Hadi M Yassine, Muhammad Irfan Ullah, Aziz Rahman, Zahid Kamran, Muhammad Umar Sohail. White Button Mushroom, Agaricus bisporus (Agaricomycetes), and a Probiotics Mixture Supplementation Correct Dyslipidemia without Influencing the Colon Microbiome Profile in Hypercholesterolemic Rats. Int J Med Mushrooms. 2020 ;22(3):235-244. PMID: 32479018

K Khatun, H Mahtab, P A Khanam, M A Sayeed, K A Khan. Oyster mushroom reduced blood glucose and cholesterol in diabetic subjects. Mymensingh Med J. 2007 Jan;16(1):94-9. PMID: 17344789

[xxvii] K Khatun, H Mahtab, P A Khanam, M A Sayeed, K A Khan. Oyster mushroom reduced blood glucose and cholesterol in diabetic subjects. Mymensingh Med J. 2007 Jan;16(1):94-9. PMID: 17344789

[xxviii] Sijian Zheng, Shihao Deng, Yun Huang, Mi Huang, Ping Zhao, Xinhua Ma, Yanzhang Wen, Qiang Wang, Xinzhou Yang. Anti-diabetic activity of a polyphenol-rich extract from Phellinus igniarius in KK-Ay mice with spontaneous type 2 diabetes mellitus. Food Funct. 2018 Jan 24 ;9(1):614-623. PMID: 29271444

[xxix] Junling Yang, Huibin Dong, Ya Wang, Yun Jiang, Wenna Zhang, Yongming Lu, Yan Chen, Lei Chen. Cordyceps cicadae polysaccharides ameliorated renal interstitial fibrosis in diabetic nephropathy rats by repressing inflammation and modulating gut microbiota dysbiosis. Int J Biol Macromol. 2020 Nov 15 ;163:442-456. Epub 2020 Jun 24. PMID: 32592781

[xxx] Tao Jiang, Liang Wang, Angjie Ma, Yi Wu, Qiwen Wu, Qiulin Wu, Jianwei Lu, Tian Zhong. The hypoglycemic and renal protective effects of Grifola frondosa polysaccharides in early diabetic nephropathy. J Food Biochem. 2020 Oct 11:e13515. Epub 2020 Oct 11. PMID: 33043487

[xxxi] Thi Nhu Ngoc L, Oh YK, Lee YJ, Lee YC. Effects of Sparassis crispa in Medical Therapeutics: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Int J Mol Sci. 2018 May 16;19(5):1487. doi: 10.3390/ijms19051487. PMID: 29772715; PMCID: PMC5983641.

DianeFulton

Dr. Diane Fulton is Emeritus Professor at Clayton State University. She holds Ph.D./MBA in Business (University of Tennessee – Knoxville) and B.S. with Math/Secondary Education majors (University of Wisconsin – Milwaukee). During her 45-year career as administrator/professor teaching research and business, she authored 10 books, over 50 articles, and is now writing children’s books about the body, mindfulness and cross-cultural awareness. Her passion is to share her knowledge to integrate a healthy body, mind and soul. To reach her: Clayton University’s Emeritus Professors  Diane Fulton LINKED IN or Diane Fulton FACEBOOK.

Category:

diet and nutrition, research, Supplements, Treatment

120 Doctors Ask JAMA to Retract Misleading Columbian Study Downplaying Efficacy of Ivermectin

https://www.theblaze.com/op-ed/horowitz-120-doctors-ask-jama-to-retract-misleading-colombian-study-downplaying-efficacy-of-ivermectin

Horowitz: 120 doctors ask JAMA to retract misleading Colombian study downplaying efficacy of ivermectin

OP-ED

Why is there such an agenda to discredit cheap, repurposed drugs?
DANIEL HOROWITZ

April 16, 2021

We knew this would happen. The health establishment didn’t use fabricated data from a study authored by a science fiction writer and porn star (later retracted), as they did with hydroxychloroquine, but it was almost as bad.

No, they didn’t find any harm from ivermectin, but after every study showing the amazing efficacy of ivermectin against SARS-CoV-2 at every stage of the disease, the media breathlessly promoted a Colombian study supposedly showing no statistically meaningful benefit among those COVID-19 patients who were treated with it.

Last month, a group of Colombian researchers published a study in the Journal of the American Medical Association (JAMA) concluding that, contrary to the findings of every other study, ivermectin showed no signs of bettering outcomes in COVID-19 patients in Cali, Colombia.

“Among adults with mild COVID-19, a 5-day course of ivermectin, compared with placebo, did not significantly improve the time to resolution of symptoms,” concluded the authors. “The findings do not support the use of ivermectin for treatment of mild COVID-19, although larger trials may be needed to understand the effects of ivermectin on other clinically relevant outcomes.”

(See link for article)

 
**Comment**
 
Once again the spin-doctors are hard at work discrediting a powerful, cheap drug that works on COVID.
 
The article points out:

After ignoring dozens of other studies on ivermectin for months, the New York Times got hold of this study the day it was published and penned an article titled, “Popular Drug Does Not Alleviate Mild Covid-19 Symptoms, Study Finds.”

Horowitz points out the study was flawed from the beginning and its results do not support the authors’ conclusions.
Thankfully, honest doctors are screaming bloody-murder and have written a letter  to JAMA:

The study’s flaws span subject population, design, execution and controls. The small sample size (n = 400) had a median age of 37 and a BMI of 26, making them extremely low risk for COVID-19 hard endpoints. Faced with this low-relevance study group, the study authors improperly changed primary endpoint midway, moving the main endpoint to full symptom resolution by day 21. This self-reported subjective endpoint, obtained through telephone survey, is not credible for avoiding nondifferential nullward bias of the results.

The authors incorrectly administered ivermectin on an empty stomach, reducing drug bioavailability in lung tissue, the critical drug target, by a factor of roughly 2.5. Additionally, ivermectin is readily available over-the-counter in Colombia, where sales have been ubiquitous (1.6 doses per COVID-19 case) in Cali during the study period.[2] Lack of serum testing in the study prevented identification of subjects who may have used the drug at intervals longer than the study lookback.

Thus, you literally had a placebo control group where they didn’t ensure they were not taking ivermectin! On top of this, the department of health in the state of Valle del Cauca – where this study took place – began distributing ivermectin to COVID patients right when the study period began.

Also, just from June to July of last year when the study period began, over-the-counter sales of ivermectin in the Cali region quintupled.

The doctors protesting this study originally sent this letter to JAMA to be published, but after JAMA declined, the authors posted it as an open letter on their own landing page.

Horowitz also points out they violated participant consent rules by not telling the study participants they were receiving ivermectin.

The Front Line COVID-19 Critical Care Alliance (FLCCC), which is the lead group in the United States promoting ivermectin as the staple of COVID early therapeutic treatment, wrote a paper calling into question the protocols of the study, noting that a labeling error substituted 38 ivermectin doses as part of the placebo group.

They also accuse the authors of a conflict of interest for receiving grants from “Sanofi Pasteur, a vaccine manufacturer; Janssen, a J&J vaccine partner; and GlaxoSmithKline, Merck, and Gilead, which manufacture COVID-19 drugs.”

Oops.  

Meanwhile, Gilead is raking in the dough through its sale of Remdesivir (over $3K per treatment) despite ZERO evidence of efficacy.  It’s still being used as the only major treatment, while the FDA is now going after anyone who mentions things like vitamin C, zinc, and other natural remedies.

And never, ever forget the atrocious, fraudulent, government funded study on HCQ which was finally retracted, and the fact the AAPS sued the FDA for “irrational” interference of Access to life-saving Hydroxychloroquine.”

All research needs independent scrutiny.  I’m eternally grateful for the doctors and researchers who do this work on their own dime.  Without this exposure, the world would blindly accept fraudulent studies.  It’s also up to us to educate others on this diabolical take-over of science and the need to question ALL OF IT.
We are living in 1984.
 
 

Category:

Treatment, Viruses