Fatigue, muscles aches, brain fog—are these symptoms of chronic Lyme disease, or merely side effects of the daily grind of human existence? It’s hard to tell.
Chronic Lyme disease, also known as post-treatment Lyme disease syndrome or PTLDS, is incredibly hard to diagnose because symptoms vary greatly, and there is currently no biological test to detect the disease.
Now, Kim Lewis, University Distinguished Professor of biology and director of the Antimicrobial Discovery Center at Northeastern, has proposed a new way to objectively diagnose this elusive disease by analyzing the microbes in a patient’s gut. (See link for article)
A few points of consideration:
- The article falsely states that 10-20% go on to suffer with symptoms – 800,000 by their estimation. It’s far, far more than that. Their number needs to be doubled to even get remotely close to reality according to microbiologist Holly Ahern: https://madisonarealymesupportgroup.com/2019/02/25/medical-stalemate-what-causes-continuing-symptoms-after-lyme-treatment/
- The author is obviously clueless as they have the audacity to compare this madness to the ‘side effects of the daily grind of human existence’ which historically came straight out of Gary Wormser’s mouth. Not being able to get out of bed is a far cry worse than ‘aches and pains of daily living!’
- Dr. Lewis more accurately states that Lyme prevents people from having a normal life.
- He also says some doctors don’t believe in chronic Lyme.
- The study compared fecal matter from healthy people, ICU patients, and PTLDS patients and found that people with PTLDS have two distinct differences in microbial levels compared to the other groups—an abundance of a type of bacteria called Blautia (usually seen in obesity, Alzheimer’s, and MS) and a suppression of a type of bacteria called Bacteroides (help regulates digestion, inflammation, immune responses and produces GABA, the neurotransmitter that wards off anxiety & depression).
- ICU patients on antibiotics did not experience these same changes suggesting antibiotics alone are not responsible for the difference.
- Lewis believes this will provide a potential diagnostic tool as well as new treatments.
“If we can fix the microbiome, then we could perhaps find an intervention for PTLDS,” Lewis says.
https://madisonarealymesupportgroup.com/2015/07/07/promising-new-research-for-persisting-lyme/ Interestingly, Lewis’ past research focused on borrelia persistence. This is what he found:
His team started by killing Borrelia (the causative agent of Lyme Disease) with antibiotics and waiting three weeks. He expected and found that persisters remained. He found this promising as it helps explain why many continue to have symptoms.
He tried numerous things against the persisters – all of which failed, until they focused on Borrelia’s weakness: it doesn’t develop antibiotic resistant “superbugs.” From this conclusion they decided to manipulate dosing by killing the Borrelia, waiting, and then going back and hitting them again. After doing this four times, the researchers discovered no bacteria in the petri dishes.
This is what Dr. Burrascano found clinically as well. He called it ‘cycling’ antibiotics and cured himself and many of his patients with this method. He also found blood levels of antibiotics were important as well: https://madisonarealymesupportgroup.com/2018/12/28/the-history-of-lyme-disease-dr-burrascano/