The People With Hidden Immunity Against COVID-19
The clues have been mounting for a while. First, scientists discovered patients who had recovered from infection with Covid-19, but mysteriously didn’t have any antibodies against it. Next it emerged that this might be the case for a significant number of people. Then came the finding that many of those who do develop antibodies seem to lose them again after just a few months.
In short, though antibodies have proved invaluable for tracking the spread of the pandemic, they might not have the leading role in immunity that we once thought. If we are going to acquire long-term protection, it looks increasingly like it might have to come from somewhere else. (See link for article)
The article points out that the researchers tested blood samples years before COVID and found T Cells specifically tailored to detect proteins on the surface of it. They found some could test negative for antibodies but positive for T cells that identify COVID. The finding is prevalent – 40-60% of unexposed individuals had these cells.
They now believe immunity is twice as common as previously thought.
Highly specific T cells hang around in the blood years after an infection and continue to identify and kill pathogens contributing to the immune system’s “long-term” memory, especially when it recognizes an old foe.
The article explains that the innate immune system, made up of white blood cells and chemical signals, is the first line of defense which then starts the production of antibodies weeks later. A little less than a week after infection, T cells get activated and start recognizing infected cells. The T cells or other parts of the immune system they recruit then eliminates the invaders before they can create viral factories that churn out copies.
This explains why antibody testing is fruitless at the beginning of infection, as Lyme/MSIDS patients are painfully aware. Also, here is a picture of borrelia (Lyme) living quite happily with a macrophage: https://madisonarealymesupportgroup.com/2019/06/26/fluorescent-image-of-borrelia-living-quite-happily-with-a-macrophage/
There are 4 types of T cells:
- Helper T cells cooperate with B cells in antibody production and activation of macrophages and inflammation.
- Memory T cells persist in the blood stream to provide protection for future infections.
- Suppressor T cells protect healthy tissues.
- Killer T cells kill virus infected cells directly.
When it is proven & accepted that Bb infects white blood cells, it will give a potential answer to some late-disseminated Lyme cases as an immune-deficiency syndrome demonstrating why some patients have frequent and prolonged infections and may acquire new allergies as well as Mast Cell issues.
This is extremely important work that must be done if the Lyme community is to move forward. We don’t need more climate data, we need research on pathogen persistence, better testing, better treatment, and a host of other crucial issues that will actually help Lyme patients. Make sure you express this to Congressman Frank Pallone as well as demanding a hearing on the issues of Lyme before HHS gets another dime of tax-payer money: https://madisonarealymesupportgroup.com/2020/08/02/house-approves-increased-funding-for-lyme-im-not-impressed-please-contact-congressman-pallone/