Entomologist Larry Dapsis, Deer Tick Project Coordinator, of Cape Cod Cooperative Extension presents information about numerous types of ticks and the diseases they carry in the following Tickology video series.

Tickology

 Approx. 9 Min

Tick Identification & Ecology

Take aways:

  1. Female American Dog Tick is easy to spot as she has a creamy white wide spot up by the head.
  2. Female Lone Star tick has a bright white spot in the center of her back.
  3. Female Deer Tick has a bright red abdomen.
  4. A lot of this info is shared again in part 3 below where I have more notes.

 Approx. 12:30 Min.

Tick Borne Diseases

Take aways:

  1. He considers the American Dog Tick more of a nuisance than a threat.  I disagree.  Just ask anyone who’s ever had RMSF or Tularemia, both of which can kill you.
  2. The Deer Tick (Black legged tick) is endemic in 80 countries and has been here for thousands of years.
  3. Lyme is found in 49 out of 50 states in the U.S. (absent only in Hawaii)
  4. In 2016 the CDC adjusted Lyme prevalence to 300,000 new cases of Lyme a year.
  5. Martha’s Vineyard has more cases than anywhere in the universe.
  6. Risk of infection is year round.
  7. Largest risk is from the nymph as they are smaller and the bite is difficult to detect.   He is finding about 25% to be infected with Lyme.  50% of adults are infected.
  8. In Massachusetts, children ages 5-9 have the highest rates of infection.  Adults aged 50-70 has a surge of infection as well.
  9. Babesiosis, similar to Malaria, can be passed via blood transfusion with 50% of Massachusetts cases found in the south eastern part of the state and virtually found in some degree in every county in the state.
  10. Anaplasmosis (HGA) can look similar to Lyme and is more broadly distributed in Mass.
  11. All these diseases are steadily increasing.  95% of cases are aged 65 and older.
  12. Borrelia miyamotoi, related to Lyme, is a relapsing fever.  3% of Cape Cod ticks have it but is expected to increase.
  13. Powassan can put you in the hospital with brain swelling.  They did surveillance and found Powassan in 4 out of 6 site sites with infection rates as high as 10% in the tick population.  In reading the literature, he feels it has been on Cape Cod for thousands of years but it hasn’t been on medical radar.

  Approx. 8 Min.

Lone Star Tick – The New Tick in Town

Part 3 of the Tickology video project.

Take aways:

  1. The Lone Star Tick, normally considered a Southern tick, is in Cape Cod, and has moved North, and yes, is in Wisconsin.
  2. The adult female has a white dot on her back
  3. These ticks can run and are aggressive, fast & will actually chase you.  
  4. While he mentions a warming climate, independent Canadian tick researcher, John Scott, states emphatically temperature has nothing to do with tick expansion:  https://madisonarealymesupportgroup.com/2018/08/13/study-shows-lyme-not-propelled-by-climate-change/
  5. He claims Lone Star ticks have been established in Sandy Neck Beach Park and Shining Sea Bike Trail for a long time – it’s just nobody was looking for them.  I suspect this to be true for many other areas as well.
  6. He claims these areas are “perfect flyways” for migratory birds for transporting ticks.
  7. Lone Star ticks prefer intermediate size hosts.  He put out video surveillance and picked up wild turkeys in areas where these ticks were established.  Rabbits & coyotes are good hosts as well
  8. The adult female lays a cluster of 4,000-5,000 eggs,  which leaves a high concentration of larvae in late summer.  He claims when you find one, it could be a matter of minutes and you could have 200-300 bites.
  9. He claims Lone Star tick larvae do not transmit pathogens.
  10. The adults; however, can transmit Erlichiosis, STARI, Tularemia and Alpha Gal or meat allergy (all animal products).
  11. He claims you will not find deer ticks in an open lawn.  I was told otherwise by Susan Paskewitz, chair of the Department of Entomology at UW–Madison, whose crew is finding them in fields where kids are playing sports, and it’s here as well: https://newyork.cbslocal.com/2018/05/07/ticks-lyme-disease-cdc-putnam-county/
  12. He is finding Lone Star ticks in open spaces.  They don’t mind the heat.  Deer ticks will seek out leaf litter and/or snow when conditions are harsh.

 Approx. 13:22 Min

Permethrin Treated Clothing & Footwear

Take aways:

  1. Natural Pyrethrum is from the Aster Family, & is an extract from a type of chrysanthemum.  It has quick knockdown against insects but no residual control.  Breaks down in sunlight quickly.
  2. They manipulated it so now it has 4 weeks of residual control.
  3. You only use it on clothing and footwear.  He feels treating footwear to be crucial.  If a tick is on a treated surface with permethrin for 60 seconds it will die.  He feels strongly that using this product will reduce your exposure tick bites by upwards of 90%.  It is active thru 6 washings or 45 days which ever comes first.
  4. Pre-treated tick repellent clothing is also available.  EPA testing has shown it is active through 70 washings.  You can also send your clothing to “Insect Shield,” and they will treat your clothing and send it back with the 70 washing claim.  He says it’s about $10 per clothing item.
  5. It’s not the molecule that makes the poison, it’s the dosage.  As far as permethrin goes, there is low mammal toxicity except for cats.  It is 2,250 times more toxic to ticks than to humans.  According to the EPA, permethrin-treated clothing poses no harm to infants, children, pregnant women, or nursing mothers.
  6. Permethrin has low skin absorption and is metabolized quickly.
  7. National Research Council looked at long term exposure on the military wearing permethrin saturated clothing from head to foot for 18 hours a day for 10 years and found no reason for an adverse effect.
  8. The active ingredient is the same ingredient used for treating scabies and head lice and parents smear it on their kids from head to toe.
  9. He demonstrates how to apply it onto clothing and footwear.  Scroll to 10:00.  Make sure to wash these treated cloths away from other clothes.  Remember sunlight breaks it down so it lasts through 6 washings for 45 days, which ever comes first.
  10. He sprays the inside of the legs in case a tick gets underneath.  I tuck my pants into my white sprayed socks so ticks can not get inside.

 Approx. 6 Min

Skin Repellents

Take aways:

  1. The big distinction between repellents is the EPA registration.  Deet, Picaridan, IR 3535, and Oil of Lemon Eucalyptus have EPA registration with data on file for any claim being made.
  2. Go here for the EPA selection guide:  https://www.epa.gov/insect-repellents/find-repellent-right-you  (Fill in the questionnaire)
  3. Go to www.npic.orst.edu for pesticide information.
  4. Go to capecodextension.org for short factual answers on products.
  5. Naturals are not EPA registered so there is no data proving effectiveness.  Not all repel ticks.  Buyer beware.

__________________

For more on tick prevention:  https://madisonarealymesupportgroup.com/2017/05/11/tick-prevention-and-removal-2017/

https://madisonarealymesupportgroup.com/2018/06/06/mc-bugg-z/

https://madisonarealymesupportgroup.com/2018/05/27/study-conforms-permethrin-causes-ticks-to-drop-off-clothing/  “All tested tick species and life stages experienced the ‘hot-foot’ effect after coming into contact with permethrin-treated clothing,” Eisen said. 

https://madisonarealymesupportgroup.com/2018/04/03/fire-good-news-for-tick-reduction/  Study found a 78-98% reduction in ticks.
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0112174 These data indicate that regular prescribed burning is an effective tool for reducing tick populations and ultimately may reduce risk of tick-borne disease.

 

 

Recently I discovered that for $10 you can plug your genetic data into a very practical website http://foundmyfitness.com/ that will help you understand your genetic data as well as give you practical steps you can take to improve it. 

In this talk Rhonda Perciavalle Patrick, Ph.D. hits on vitamin D (an important hormone in brain function and dysfunction) as well as the MTHFR polymorphism (results in high homocysteine requiring supplementation with L methyfolate) which many Lyme patients have.  She also discusses limiting food intake as a method of affecting gene suppression in a positive way (calorie restriction & intermittent fasting).  She also discusses how using a sauna and exercise increases longevity. 

 Approx. 1 hour

Nutrigenomics, Epigenetics, and Stress Tolerance

Our genes influence the way we absorb and metabolize micronutrients. Nutrigenomics looks at the influence genetic variation has over micronutrient absorption/metabolism and the biological consequences of this dynamic relationship. Our diet also influences which of these genes are turned on or off! Emerging evidence in the field of epigenetics has demonstrated that not only can we change the expression of our own genes within our own lifetime; sometimes these changes are heritable and affect our children and grandchildren. This talk explores the intersection between genetics, nutrition, and environment: how your diet, micronutrients, exercise, heat stress, and sleep can change the expression of your genes and how this has profound effects on the way your body functions and ages.

For a brief explanation on Vitamin D by Rhonda:    Approx. 4:30
  • 30-80ng/ml the Sweet spot
  • Fish is a great source of D
  • Get your D levels tested regularly

Rhonda Perciavalle Patrick, Ph.D. is an assistant scientist at Children’s Hospital Oakland Research Institute and is a science communicator for a broad lay audience via her web and video presence found at FoundMyFitness.com.  It is Rhonda’s goal to challenge the status quo and encourage the wider public to think about health and longevity using a proactive, preventative approach.

Rhonda earned her Ph.D. in biomedical science from the University of Tennessee and performed her graduate research work at St. Jude Children’s Research Hospital. She also has a Bachelor’s of Science degree in biochemistry/chemistry from the University of California, San Diego. She has done extensive research on aging, cancer and nutrition, and metabolism.

________________

For more on MTHFR and methylation:

https://madisonarealymesupportgroup.com/2018/03/23/altered-dna-methylation-mental-illness-lyme-msids/

https://madisonarealymesupportgroup.com/2018/04/09/3-part-series-on-genetic-mutations/

https://madisonarealymesupportgroup.com/2018/08/01/methylation-what-you-need-to-know/

 

https://drjaydavidson.com/root-canals-cavitations-lyme/?inf_contact_key=8636f3a3f9f27c5b6b9c66f743c1ca40e3a271ca1fcdcf412ea22981edb526d0

277716_Lyme-cavitation-article_1st-page_082918

By Dr. Jay Davidson

ARTICLE SUMMARY

  • Complications and infections following dental work, including infected root canals or areas of dead jaw bone called cavitations, can cause systemic harm throughout our bodies and impede healing from Lyme and related infections.
  • Infected root canals and cavitations don’t cause symptoms within the mouth, and often go undetected.
  • Cavitations, pockets of dead, infected jaw bone, are extremely common following dental procedures including tooth extractions and root canals. Up to 90% of tooth extractions lead to cavitations.
  • Infected cavitations keep treatment from reaching our brains, and can’t be accessed by our immune systems.
  • Cavitations are ideal breeding grounds for bacteria and infections that can spread throughout the body.
  • Cavitations are not detected during routine dental examinations, but can be searched for by biological dentists using a CAVITAT scanner.
  • Root canal treatments leave behind dentin tubules but cut off blood flow, creating a perfect breeding ground for harmful, anaerobic bacteria and Lyme-related microbes.
  • Root canal treatments have been linked to cancer and a number of chronic diseases but are still the go-to treatment for dying teeth.
  • It’s best to avoid root canal treatments if possible, in favor of less harmful options such as non-titanium implants, bridges, or partial dentures. If you’ve already had a root canal treatment, it should be removed if it’s been infected.
  • Cavitations can be addressed with surgery to clean out the jaw bone or x-tip ozone injections to kill harmful bacteria.
  • It’s extremely important to support the immune system before, during, and after treatment for cavitations, and to focus on detoxing.
  • For more in depth guidance on this and other critical steps towards recovery, sign up for my at-home Lyme disease program or apply for one-on-one coaching.

ARE ROOT CANALS OR HIDDEN JAW INFECTIONS KEEPING YOUR LYME DISEASE ALIVE?

We rarely think about our mouths or teeth contributing to illness in our bodies. After all, most of us have a dentist dedicated to the health of our teeth, and separate doctors to help us take care of the rest of our bodies. When we have a tooth problem that needs fixing, we go to see our dentists, undergo any necessary procedures, and then we move on. But what most people don’t know is that complications and infections following dental work can cause serious and systemic harm throughout our bodies… and because these infections rarely cause symptoms within the mouth, most of us don’t even know that they’re there.

If you are finding yourself stuck and unable to recover from Lyme or a chronic infection in spite of your best efforts, it may be time to look into the possibility of infections that are hiding behind your teeth.

THE MOUTH/BODY CONNECTION

The mouth is often talked about as being the gateway to the body. It is the point of entry not only for the food we eat and the water we drink but even for the air that we breathe. Because of the multitude of infections, pathogens, and toxins that can find their way into our bodies through our mouths, the immune system is active there, and we are equipped with an oral microbiome to help protect us. The mouth, in other words, houses our first line of defense.

Of course, it isn’t just food and water that we’re putting into our mouths. When we have dental work done, we are allowing any number of materials in. Amalgam (silver) fillings, crowns, retainers, and titanium implants can all contribute to toxicity and neurological symptoms associated with Lyme, Bartonella, and related infections.

Beyond metal in the mouth, cavitations– infected areas of jaw bone resulting from tooth extractions and root canals– can impede healing from Lyme and any number of other chronic infections.

WHAT ARE CAVITATIONS? 

So, what ARE cavitations? Basically, cavitations are areas of dead, infected jaw bone. These holes in the jaw bone commonly form after a tooth extraction, wisdom tooth removal, or root canal treatment, when periodontal ligaments from an extracted tooth are left behind and block the growth of new bone by cutting off circulation to the area. These areas of dead bone often become home to insidious bacterial infections.

Infected cavitations can create a barrier preventing treatment for Lyme from reaching the brain. Cavitations can occur in the lower or upper jaw, the latter of which is connected with the skull.

It is estimated that 77 – 90% of routine tooth extractions lead to cavitation infections 1. The trouble is that these infections rarely, if ever, cause localized symptoms (like tooth pain or swelling), and they are not detected during routine dental examinations or even on regular x-rays.

HOW CAVITATIONS KEEP LYME ALIVE

Cavitations create a perfect environment for Lyme and all kinds of bacteria and parasites to breed in hiding. Cavitations are considered focal infections, meaning that they originate in one place but can spread to other parts of the body. But although these bacterial infections can spread throughout the body, our immune system can’t reach them. Not only can we not fight the infection at its source, cavitations compromise the immune system overall: and when the immune system is already weakened because of Lyme or another chronic infection or disease, this affects us even more.

In addition to promoting systemic infection, cavitations actually create a barrier that prevents us from accessing and eliminating pathogens in the brain. So, you may be undergoing treatment for Lyme, but if you have a cavitation, that treatment may be unable to reach the head where it’s needed.

Cavitations are sneaky. They can cause chronic infection throughout the body and keep Lyme active and alive, but they often go undetected because one thing they don’t do is cause symptoms within the mouth.

 

Cavitations Barrier to Healing Dr. Jay Davidson

HOW TO DETECT CAVITATIONS

So, how can you determine whether or not you have a cavitation that’s holding you back from healing? If you’ve ever had a root canal treatment or a tooth extraction, including removal of your wisdom teeth, you may have a cavitation. Cavitation infections are extremely common, and are even more likely if your immune system has already been weakened because of another kind of infection.

Unfortunately, conventional dentists are not trained to look for or be concerned about cavitations, which are not obvious or visible during any kind of routine check-up. Biological dentists, who take a more natural and holistic approach that factors in connections between toxins, environmental exposures, the mouth, and the body, can usually help.

A biological dentist who is trained to detect cavitations will generally use a specific type of ultrasonic tool called a CAVITAT scanner to search for areas of dead and infected bone. If they do find a cavitation, don’t panic! Once they’ve found the area that’s been housing the infection, the next step is to help you to eliminate it, and enhance your overall healing.

It is recommended that you get checked for cavitations once every two years if you’ve had a tooth removed or a root canal.

HOW ROOT CANALS CAN KEEP LYME ACTIVE

Let’s zero in on root canals for a minute. Anyone who has ever had one will wince at the mention of this dental procedure. When a tooth is dead or dying, a root canal treatment is usually done. During this procedure, the pulp inside the tooth is removed. The tooth is cleaned out and disinfected, and then the root canal is shaped, and a filling is put in. The overall benefit of a root canal treatment is that you get to save your tooth (and get rid of the pain that it may have been causing you).

The problem is that although dentists are removing the part of the tooth that is infected, they are leaving behind the periodontal ligament, a connective tissue structure that is an ideal breeding ground for certain kinds of harmful bacteria2. The filling that is put into the tooth cuts off blood supply throughout the area. The dentin tubules (microscopic communication channels) that have been left behind are no longer a bi-directional highway for helpful microbes; they are now a direct route to a hiding place for harmful bacteria that thrive without oxygen. These bacteria, called anaerobic because of their ability to live and breed in environments without oxygen, can multiply like crazy and spread throughout our bodies, causing or contributing to chronic inflammation, neurological symptoms, and systemic infection.

Lyme-related microbes can make themselves right at home around a root canal, and other infections can aggravate and contribute to Lyme symptoms as they leak out into the bloodstream. Toxins, pathogens, and infections can leak and spread from dentin tubules, with the power to affect the whole body, but the immune system can’t get to them, and neither can any kind of treatment that we may be using to eliminate infection.

Unsurprisingly, the links between infected root canals and chronic disease do not end with Lyme and its co-infections. Diabetes, heart disease, kidney disease, Irritable Bowel Disease, arthritis, and lupus are among the other conditions with connections to root canals 3. Links between root canals and cancer have also been found, most famously by Dr. Josef Issels, a forward-thinking German physician who decades ago reported that 97% of his cancer patients had undergone at least one root canal procedure.

By some estimates, 75% of teeth that have had root canals develop tubule infections.

Dr. George Meinig, an endodontist (root canal specialist) who was one of the founders of the American Association of Endodontists and helped to popularize the procedure, learned later in his life and career about the high risk of infection and subsequent links to chronic disease that were associated with root canals, and began to advocate for putting an end to them. Dr. Meinig wrote a book on the subject, explaining the dangers involved in root canal treatments and exposing a cover-up of relevant research by the American Dental Association. Unfortunately, root canals continue to be the go-to treatment for dead and dying teeth within conventional dentistry, with an estimated 41,000 procedures performed every day 4.

INFECTED ROOT CANALS AND CAVITATIONS BLOCK LYME TREATMENT

So, practically speaking, how does this affect your healing process? You may be following a well-researched protocol to recover from Lyme involving a specific combination of herbs, antibiotics, and/or other treatments, but cavitations create an actual barrier blocking these treatments from reaching the head. Treatments are also unable to reach the dentin tubules where infections are often hiding, and where Lyme spirochetes may be silently breeding. If your protocol just doesn’t seem to be working, this may be why.

Infected root canals and cavitations can also hinder drainage, meaning that if you are undergoing treatment to cleanse Lyme and parasites, the toxins that are being released are not being eliminated properly. This can cause symptoms of die-off that may actually cause you to feel worse instead of better while you’re trying to heal.

These are some of the major reasons why cavitations and infected root canals need to be removed for complete recovery of Lyme. For comprehensive guidance and protocols on preparing the body for cavitation surgery or root canal removal and supporting the immune system throughout the process, as well as a protocol for amalgam filling removal which can be another huge hindrance to healing, sign up for my at-home Lyme disease program or apply for one-on-one coaching.

WHAT TO DO ABOUT ROOT CANALS

Of course, we want to try and avoid getting root canal treatments if we can. If a tooth is dying and cannot be repaired, other options including bridges, non-titanium implants, or partial dentures may be possible and can be discussed with your dentist (ideally a biological dentist).

If you already have one or more, it’s important to check for infection in the area, and discuss options with a biological dentist, who will take into account your Lyme disease and overall health when determining how to best move forward. Although the root canal itself may not cause problems if it isn’t housing an infection, the likelihood of infection now or in the future is high enough that your biological dentist may recommend removing the root canal no matter what. If a cavitation is found, then the root canal should be removed in order to allow treatment to progress.

WHAT TO DO ABOUT CAVITATIONS

If your biological dentist has found an infected cavitation, it’s time to tackle it so that you can regain control of your healing process! There are a few different options here, and they can be discussed with your dentist and any other practitioners who you’re working with.

Surgery is sometimes required in order to remove dead bone. Another possibility is x-tip ozone injections. This is a relatively simple and painless procedure that involves numbing the area and injecting ozone into the jaw bone to kill harmful bacteria and pathogens that are hiding there. This procedure may leave you with a sore jaw for a few days afterwards. Generally, 5-7 injections are necessary to completely kill off the pesky residents of your cavitation. Depending on the severity of your cavitation, ozone injections may be recommended in addition to or in place of surgery.

Low-level laser therapy is another method that is sometimes used for bone regeneration.

It’s important to make sure that your immune system is being supported before, during, and after surgery and/or ozone injections, as pathogens and infections are being released. It’s not uncommon to feel temporarily worse a few days after surgery as toxins pass through the body, but there are many ways to support your body through the process.

Detoxing may be recommended following surgery or an ozone treatment in order to give the immune system an extra boost. Supplementation with certain vitamins and minerals, as well as detoxification methods like coffee enemas or castor oil packs may be recommended after surgery.

TIPS FOR KEEPING YOUR MOUTH HEALTHY

In addition to trying to avoid root canals and repairing damage that may have been caused by dental work, there are a few things we can all do on a regular basis to support our overall health by way of our mouths and teeth.

Remember that microbiome in the mouth? Processed foods, artificial colors and flavors, and refined sugar will all disrupt its balance, weakening our body’s first line of defense. Hopefully you are already avoiding these things, but this is just another reason to!

Many toothpastes and mouthwashes also contain chemicals that harm our oral flora and disrupt our beneficial microbes. Switch to fluoride-free, natural toothpaste and natural mouthwash options to support friendly mouth microbes, and make sure that you are replacing your toothbrush regularly. Rinsing the mouth with sea-salted or ozonated water can also help to support your oral health.

It is also a good idea, regardless of whether or not you have cavitations or root canals, to work with a biological dentist if you can find one in your area.

Mouth Health Tips Dr. Jay Davidson

HOW TO FIND A BIOLOGICAL DENTIST

When it comes to repairing possible systemic damage caused by dental work and preventing future problems, it’s crucial to work with a dentist who takes a more holistic approach and is trained to view and work with your teeth in harmony with your body.

There is an excellent organization called the International Academy of Oral Medicine & Toxicology that is made up of biological dentists who understand and take into consideration factors like toxins and infections, and the many connections between oral health and overall wellness. This is a great place to start when you’re looking for a dentist who will work with you to address concerns related to cavitations and root canals as well as other serious inhibitors to healing like amalgam fillings, and who will help to advise you on supporting your body and immune system through any dental procedures.

When undergoing surgery or treatments to remove cavitation infections, you may want to work with a biological dentist in conjunction with your Lyme coach or practitioner to make sure that your body and immune system are being supported from all angles.

CONCLUSION

It can be overwhelming to think about damage that may already have been done because of past dental work, but there is always a way to work through and repair that damage. The most important thing is getting to the root (no pun intended) of the problem, and working on treating it and on healing.

If you feel like you’ve hit a wall in your Lyme recovery, addressing possible infected root canals and cavitations may be one of the most important steps that you take.

To learn more, watch my conversation with biological dentist Dr. Gerry Curatola.

For much more in depth guidance on this and other critical steps towards recovery, sign up for my at-home Lyme disease program or apply for one-on-one coaching, and get ready to regain control of your health!

  1. Huggins HA, Levy TE. Routine dental extractions routinely produce cavitations. J Adv Med. 1996; 9(4) Web.
  2. Nagaoka, Shigetaka, et al. “Bacterial Invasion into Dentinal Tubules of Human Vital and Nonvital Teeth.” Journal of Endodontics, vol. 21, no. 2, 1995, pp. 70–73., doi:10.1016/s0099-2399(06)81098-8. Web.
  3. Levy, Thomas E. “Oral Pathogens: A Common Cause of Chronic Disease.” Journal of Orthomolecular Medicine, vol. 31, no. 1, 2016. Web.
  4. Endodontic Facts, American Association of Endontists.

_________________

For more:  https://madisonarealymesupportgroup.com/2018/09/11/oral-surgical-procedures-chronic-illness/

https://madisonarealymesupportgroup.com/2017/10/01/bartonella-in-mouth-of-hiv-infected-man/

https://madisonarealymesupportgroup.com/2018/03/23/altered-dna-methylation-mental-illness-lyme-msids/

https://articles.mercola.com/sites/articles/archive/2015/08/22/mercury-toxicity-amalgam-fillings.aspx?

Story at-a-glance –

Amalgam, also called “silver fillings,” is a consumer fraud. By referring to the color of the compound rather than its content, consumers everywhere have been tricked into placing a known neurotoxin in their mouths
Because of this cover-up by organized dentistry, aided and abetted by the U.S. Food and Drug Administration, 57 percent of Americans are unaware that amalgam is a mercury filling; 23 percent believe amalgam is made of silver; and only 11 percent of people say their dentist ever told them that amalgam contains mercury
There is no known safe level of exposure for mercury. Ideally, exposure should be zero.

https://www.nytimes.com/2018/09/29/opinion/sunday/schizophrenia-psychiatric-disorders-immune-system.html

He Got Schizophrenia. He Got Cancer. And Then He Got Cured.

A bone-marrow transplant treated a patient’s leukemia — and his delusions, too. Some doctors think they know why.
By Moises Velasquez-Manoff, science writer

CreditCreditJesse Jacobs

The man was 23 when the delusions came on. He became convinced that his thoughts were leaking out of his head and that other people could hear them. When he watched television, he thought the actors were signaling him, trying to communicate. He became irritable and anxious and couldn’t sleep.

Dr. Tsuyoshi Miyaoka, a psychiatrist treating him at the Shimane University School of Medicine in Japan, eventually diagnosed paranoid schizophrenia. He then prescribed a series of antipsychotic drugs. None helped. The man’s symptoms were, in medical parlance, “treatment resistant.”

A year later, the man’s condition worsened. He developed fatigue, fever and shortness of breath, and it turned out he had a cancer of the blood called acute myeloid leukemia. He’d need a bone-marrow transplant to survive. After the procedure came the miracle. The man’s delusions and paranoia almost completely disappeared. His schizophrenia seemingly vanished.

Years later, “he is completely off all medication and shows no psychiatric symptoms,” Dr. Miyaoka told me in an email. Somehow the transplant cured the man’s schizophrenia.

A bone-marrow transplant essentially reboots the immune system. Chemotherapy kills off your old white blood cells, and new ones sprout from the donor’s transplanted blood stem cells. It’s unwise to extrapolate too much from a single case study, and it’s possible it was the drugs the man took as part of the transplant procedure that helped him. But his recovery suggests that his immune system was somehow driving his psychiatric symptoms.

At first glance, the idea seems bizarre — what does the immune system have to do with the brain? — but it jibes with a growing body of literature suggesting that the immune system is involved in psychiatric disorders from depression to bipolar disorder.

The theory has a long, if somewhat overlooked, history. In the late 19th century, physicians noticed that when infections tore through psychiatric wards, the resulting fevers seemed to cause an improvement in some mentally ill and even catatonic patients.
Inspired by these observations, the Austrian physician Julius Wagner-Jauregg developed a method of deliberate infection of psychiatric patients with malaria to induce fever. Some of his patients died from the treatment, but many others recovered. He won a Nobel Prize in 1927.
One much more recent case study relates how a woman’s psychotic symptoms — she had schizoaffective disorder, which combines symptoms of schizophrenia and a mood disorder such as depression — were gone after a severe infection with high fever.
Modern doctors have also observed that people who suffer from certain autoimmune diseases, like lupus, can develop what looks like psychiatric illness. These symptoms probably result from the immune system attacking the central nervous system or from a more generalized inflammation that affects how the brain works.
Indeed, in the past 15 years or so, a new field has emerged called autoimmune neurology. Some two dozen autoimmune diseases of the brain and nervous system have been described. The best known is probably anti-NMDA-receptor encephalitis, made famous by Susannah Cahalan’s memoir “Brain on Fire.” These disorders can resemble bipolar disorder, epilepsy, even dementia — and that’s often how they’re diagnosed initially. But when promptly treated with powerful immune-suppressing therapies, what looks like dementia often reverses. Psychosis evaporates. Epilepsy stops. Patients who just a decade ago might have been institutionalized, or even died, get better and go home.
Admittedly, these diseases are exceedingly rare, but their existence suggests there could be other immune disorders of the brain and nervous system we don’t know about yet.
Dr. Robert Yolken, a professor of developmental neurovirology at Johns Hopkins, estimates that about a third of schizophrenia patients show some evidence of immune disturbance.
“The role of immune activation in serious psychiatric disorders is probably the most interesting new thing to know about these disorders,” he told me.

Studies on the role of genes in schizophrenia also suggest immune involvement, a finding that, for Dr. Yolken, helps to resolve an old puzzle. People with schizophrenia tend not to have many children. So how have the genes that increase the risk of schizophrenia, assuming they exist, persisted in populations over time? One possibility is that we retain genes that might increase the risk of schizophrenia because those genes helped humans fight off pathogens in the past.

Some psychiatric illness may be an inadvertent consequence, in part, of having an aggressive immune system.

Which brings us back to Dr. Miyaoka’s patient. There are other possible explanations for his recovery. Dr. Andrew McKeon, a neurologist at the Mayo Clinic in Rochester, Minn., a center of autoimmune neurology, points out that he could have suffered from a condition called paraneoplastic syndrome. That’s when a cancer patient’s immune system attacks a tumor — in this case, the leukemia — but because some molecule in the central nervous system happens to resemble one on the tumor, the immune system also attacks the brain, causing psychiatric or neurological problems. This condition was important historically because it pushed researchers to consider the immune system as a cause of neurological and psychiatric symptoms. Eventually they discovered that the immune system alone, unprompted by malignancy, could cause psychiatric symptoms.

Another case study from the Netherlands highlights this still-mysterious relationship. In this study, on which Dr. Yolken is a co-author, a man with leukemia received a bone-marrow transplant from a schizophrenic brother. He beat the cancer but developed schizophrenia.

Once he had the same immune system, he developed similar psychiatric symptoms.

The bigger question is this: If so many syndromes can produce schizophrenia-like symptoms, should we examine more closely the entity we call schizophrenia?

Some psychiatrists long ago posited that many “schizophrenias” existed — different paths that led to what looked like one disorder. Perhaps one of those paths is autoinflammatory or autoimmune.

If this idea pans out, what can we do about it? Bone marrow transplant is an extreme and risky intervention, and even if the theoretical basis were completely sound — which it’s not yet — it’s unlikely to become a widespread treatment for psychiatric disorders. Dr. Yolken says that for now, doctors treating leukemia patients who also have psychiatric illnesses should monitor their psychiatric progress after transplantation, so that we can learn more.

And there may be other, softer interventions. A decade ago, Dr. Miyaoka accidentally discovered one. He treated two schizophrenia patients who were both institutionalized, and practically catatonic, with minocycline, an old antibiotic usually used for acne. Both completely normalized on the antibiotic. When Dr. Miyaoka stopped it, their psychosis returned. So he prescribed the patients a low dose on a continuing basis and discharged them.

Minocycline has since been studied by others. Larger trials suggest that it’s an effective add-on treatment for schizophrenia. Some have argued that it works because it tamps down inflammation in the brain. But it’s also possible that it affects the microbiome — the community of microbes in the human body — and thus changes how the immune system works.

Dr. Yolken and colleagues recently explored this idea with a different tool: probiotics, microbes thought to improve immune function. He focused on patients with mania, which has a relatively clear immunological signal. During manic episodes, many patients have elevated levels of cytokines, molecules secreted by immune cells. He had 33 mania patients who’d previously been hospitalized take a probiotic prophylactically. Over 24 weeks, patients who took the probiotic (along with their usual medications) were 75 percent less likely to be admitted to the hospital for manic attacks compared with patients who didn’t.

The study is preliminary, but it suggests that targeting immune function may improve mental health outcomes and that tinkering with the microbiome might be a practical, cost-effective way to do this.

Watershed moments occasionally come along in medical history when previously intractable or even deadly conditions suddenly become treatable or preventable. They are sometimes accompanied by a shift in how scientists understand the disorders in question.

We now seem to have reached such a threshold with certain rare autoimmune diseases of the brain. Not long ago, they could be a death sentence or warrant institutionalization. Now, with aggressive treatment directed at the immune system, patients can recover. Does this group encompass a larger chunk of psychiatric disorders? No one knows the answer yet, but it’s an exciting time to watch the question play out.

Moises Velasquez-Manoff, the author of “An Epidemic of Absence: A New Way of Understanding Allergies and Autoimmune Diseases” and an editor at Bay Nature magazine, is a contributing opinion writer.

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**Comment**

This article is important on so many levels for Lyme/MSIDS patients as behavior/cognitive issues as well as immune-related issues are often present in those affected.  Killing pathogens is only one arm of treatment, that while important, is only part of the picture.  Detoxifying these pathogens as well as supporting the immune system is just as important.  Dealing with imbalances is a must.

Also noteworthy is the hyperthermia potential for Lyme/MSIDS as well as the impact of minocycline that while on it, schizophrenia patients completely normalized but when stopped their psychosis returned and how he prescribed the patients a low dose on a continuing basis.

Hmmmmm, the state medical board should come after him for overprescribing antibiotics….like they do Lyme doctors.

I personally found minocycline to be one of the most effective drugs I took.

Just for the record, I hate antibiotics, but they work.  I continue to be a human Guinea Pig and try many, many things, but nothing yet compares to antibiotics.  Recently an experienced Lyme practitioner in Wisconsin told me her patients do well off treatment for a year or two but then they suffer a relapse requiring a stint of antibiotics and/or herbs.  This has certainly been our experience as well.  

More on Mino:  https://madisonarealymesupportgroup.com/2017/06/04/minocycline-for-ms-and-much-more/

More on the Immune system and schizophrenia:  https://madisonarealymesupportgroup.com/2018/09/20/schizophrenia-breakthrough-identifies-importance-of-immune-cells/

Other brain abnormalities with Lyme/MSIDS:  https://madisonarealymesupportgroup.com/2018/07/03/lyme-meningoencephalitis-masquerading-as-normal-pressure-hydrocephalus/

https://madisonarealymesupportgroup.com/2018/03/17/how-ld-affects-your-brain-abc27-podcast/

https://madisonarealymesupportgroup.com/2018/08/25/neuropsychiatric-lyme-borreliosis-an-overview-with-a-focus-on-a-specialty-psychiatrists-clinical-practice/

https://madisonarealymesupportgroup.com/2018/08/01/risky-business-linking-t-gondii-entrepreneurship-behaviors/

BTW: t. gondii has been found in ticks (Ixodes ricinus), and these ticks also transmit Lyme and tick-borne encephalitis virus:  https://www.researchgate.net/publication/40846277_The_occurrence_of_Toxoplasma_gondii_and_Borrelia_burgdorferi_sensu_lato_in_Ixodes_ricinus_ticks_from_Eastern_Poland_with_the_use_of_PCR, and https://ecdc.europa.eu/en/disease-vectors/facts/tick-factsheets/ixodes-ricinus

https://madisonarealymesupportgroup.com/2018/02/20/mysterious-disease-where-the-body-attacks-the-brain-more-common-than-initially-thought/
https://madisonarealymesupportgroup.com/2017/10/01/panspandas-steroids-autoimmune-disease-lymemsids-the-need-for-medical-collaboration/  The story of Susannah Cahalan as well as the story of how a boy’s Lyme Disease Morphs into Autoimmune encephalopathy. It took 10 years and 20 doctors to find out 12-year-old Patrik had Lyme disease. Just 4 months later the doctors discovered he also has a condition where his immune system attacks his brain.

https://madisonarealymesupportgroup.com/2017/10/08/misdiagnosed-how-children-with-treatable-medical-issues-are-mistakenly-labeled-as-mentally-ill/

https://madisonarealymesupportgroup.com/2018/01/05/scary-side-of-childhood-strep/

https://madisonarealymesupportgroup.com/2017/12/01/guidelines-for-treating-pans-its-real/ “According to a Wisconsin specialist, 80% of his PANS/PANDAS patients have Lyme and other coinfections. This is important to know and tell others about, remembering that tick borne illness testing is abysmal. Getting to a specialist who understands this complexity is paramount. Another helpful tip is printing out and going through checklists with the children as discussing symptoms is quite helpful. Children aren’t experienced in this type of verbal specificity, so be patient and listen.

 

https://www.liebertpub.com/doi/10.1089/vbz.2018.2323

Human-Biting Ixodes Ticks and Pathogen Prevalence from California, Oregon, and Washington

Published Online:https://doi.org/10.1089/vbz.2018.2323

Abstract

From July 2006 through August 2017, a passive surveillance study of Ixodes ticks submitted from California, Oregon, and Washington was conducted by the TickReport program at the University of Massachusetts, Amherst. In total, 549 human-biting Ixodes ticks were submitted comprising both endemic and nonendemic species. We found that 430 endemic ticks were from 3 Ixodes species: Ixodes pacificus, Ixodes spinipalpis, and Ixodes angustus, whereas Ixodes scapularis (n = 111) was the most common species among the 119 nonendemic ticks. The submission peak for nymphal I. pacificus and I. spinipalpis was June, while submission peak for adult I. pacificus and nymphal I. angustus was April and September, respectively.

Endemic ticks commonly attached to the lower extremities of their victims, and individuals younger than 9 years old were frequently bitten. The infection prevalence of Borrelia burgdorferi sensu lato, Borrelia miyamotoi, and Anaplasma phagocytophilum in I. pacificus ticks was 1.31%, 1.05%, and 0.52%, respectively, and the prevalence of B. burgdorferi s. l. and A. phagocytophilum in I. spinipalpis ticks was 14.29% and 10.71%, respectively.

Furthermore, two species within the B. burgdorferi s. l. complex were detected in West Coast ticks: B. burgdorferi sensu stricto and Borrelia lanei. I. spinipalpis had the highest Borrelia prevalence among endemic ticks, and it was caused exclusively by B. lanei. Borrelia mayonii, Babesia microti, and Ehrlichia muris-like agent were not detected in these endemic ticks. In this study, we show that many nonendemic Ixodes ticks (119/549) are most likely acquired from travel to a different geographic region.

We report cases of conventionally recognized nonhuman feeders (I. spinipalpis and I. angustus) parasitizing humans.

The highest pathogen prevalence in I. spinipalpis may indicate a larger public health threat than previously thought, and the enzootic life cycle and pathogenicity of B. lanei warrant further study.

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**Comment**

OOPS!  “We report cases of conventionally recognized nonhuman feeders (I. spinipalpis and I. angustus) parasitizing humans.”

Now just how did that happen?

As we have feared all along, the barrel full of monkeys keeps rolling out of Pandora’s box.  There are far more players in the game than is being let on.  

Stay tuned.  It’s going to get uglier and uglier.