Sacrificial Virgins: Part I – Not for the greater good
The HPV vaccine is a treatment in widespread use but its efficacy in preventing cancer is medically unproven, while unintended, adverse reactions are blighting and even ending the lives of girls and young women across the world. However, pharmaceutical manufacturers and many health authorities are refusing to acknowledge there is a problem and the medical community is continuing to offer the vaccine. This is the subject of a three-part series of films – Sacrificial Virgins – the first of which was launched on YouTube on 11 September 2017.
Rob Verkerk, PhD, explains how there is no good current informed consent information being given regarding the HPV vaccine, that many medical practitioners are NOT reporting adverse events, and the importance of having accurate information in order to be able to make an informed consent. In the UK, if a child is 12, they are deemed Gillick competent and can be vaccinated against the will of their parents.
In the U.S., currently as of 2016, there are no federal vaccination laws, but all 50 states have laws requiring vaccination against diphtheria, tetanus, and pertussis (DTaP), polio, and measles and rubella (MMR); however, exemptions exist but vary from state to state. All school immunization laws grant exemptions to children for medical reasons. Almost all states grant religious exemptions for people who have religious beliefs against immunizations. Currently, 18 states allow philosophical exemptions for those who object to immunizations because of personal, moral or other beliefs.
To find your state laws: https://vaccines.procon.org/view.resource.php?resourceID=003597 I am happy to report that in my state of Wisconsin, all three exemptions exist. Please discuss this with your medical professional and consider that if your child has Lyme/MSIDS, their bodies are in a war already.
A few months ago after reading the book Master Manipulator, I wrote an article about Poul Thorsen, MD, PhD, the Danish medical researcher who produced the ‘premiere safety study’ that vaccines do not cause Autism; however, the study was produced fraudulently, but the CDC still promotes it and has not retracted it from vaccinology research, as science protocol requires.
One of the questionable studies involved is “A population-based study of measles, mumps, and rubella vaccination and autism” co-authored by Poul Thorsen, See comment in PubMed Commons below N Engl J Med. 2002 Nov 7;347(19):1477-82. It’s the study CDC particularly likes to point to regarding vaccines and Autism, and is published online here. The research was about ethylmercury in Thimerosal attributing to and/or causing Autism.
Poul Thorsen apparently was many things and probably even at cad, at that. He ingratiated himself both personally and professionally with CDC employee, Diana Schendel, PhD, who apparently was able to ‘guide’ his research around the CDC’s Atlanta headquarters.
When the CDC was notified by Thorsen’s Denmark colleagues about inaccuracies regarding CDC grants and funding, further investigation resulted “in 22 federal criminal counts – 13 counts of wire fraud and 9 counts of money laundering,” which never have been acted upon by the USA or CDC. Thorsen is hiding in plain sight, working and publishing articles in Denmark, with no extradition apparently requested by the CDC! How strange?“The United States has had an Extradition Treaty with Denmark since the Nixon Administration (1974).” (Pg. 4)
Enter into the story, Attorney Robert F. Kennedy Jr., who has been investigating mercury in vaccines (ethylmercury in the preservative Thimerosal) and mercury elsewhere in the biosphere and medicine.
Mr. Kennedy founded the World Mercury Project, whose
…Mission of the World Mercury Project is to work aggressively to reduce exposure to all sources of mercury, hold accountable those who failed to protect our planet and people from these unnecessary exposures, restore health to those who have been harmed, and to establish necessary safeguards to prevent such tragedies from ever happening again.
Thimerosal is a vaccine preservative that still is in multi-dose flu vaccines and as a residual ingredient in vaccines, since during the manufacturing process, Thimerosal is used but then extracted. CDC and FDA admit there’s a residual amount in vaccines.
For two childhood vaccines, thimerosal is used to prevent the growth of microbes during the manufacturing process. When thimerosal is used this way, it is removed later in the process. Only trace (very tiny) amounts remain. The only childhood vaccines today that have trace amounts of thimerosal are one DTaP and one DTaP-Hib combination vaccine.
Mr. Kennedy even went so far as to post a science challenge regarding thimerosal: Robert F. Kennedy Jr., Esq., offered a $100,000 reward to any journalist who “can find a peer-reviewed scientific study demonstrating that thimerosal is safe in the amounts contained in vaccines currently being administered to American children and pregnant women.” Kennedy now, however, is turning his attention to getting Poul Thorsen extradited to the USA to face legal charges. In order to explain the “Thorsen Saga,” Kennedy engaged Beth Clay to produce an update and report about Thorsen and his legal standing.
I’ve been in contact with Beth and obtained her permission to cite verbatim information she so eloquently put together and about which I thought readers ought to know. There needs to be a public outcry directed to Congress and the U.S. Attorney General to get the fictitious science surrounding Autism and vaccines mainstreamed as such, plus retracted by HHS/CDC/FDA and other nation states, including the World Health Organization. Beth’s outstanding report can be found here.
The report is 21 pages plus two pages of Exhibits. What I’d like to bring to readers’ attention are the following facts:
The U.S. CDC apparently sank $16Million into a vaccine investment fraud in Denmark!
Thorsen, apparently from the very beginning of his CDC ‘stint’, had designs of grandeur and lived high off the hog, while raising flags with his expensive Harley Davidson and suburban Atlanta home. In Clay’s paper we find,
CDC-Danish Coverup of Ethics Violations: The next day, the beginning of an ethical crisis began to take shape. Coleen Boyle, Marshalyn Yeargin-Allsopp and Diana Schendel participated in a Denmark Grantees Autism/CP conference call. Poul Thorsen participated and presumably helped bring the two new principal investigators up to speed. He was asked to provide Aarhus University a copy of all permissions in his files ASAP. Coleen commented that from what they had discussed, most of the activities were completed. Diana began discussing additional projects. Soren raised the issue of bringing the CP biomarker data to Aarhus for safekeeping. Then, there was a discussion about who had the various data and whether it could be gathered and secured all in one place. Diana and Poul were asked to provide historical context to this. Marshalyn asked if Aarhus could work with the Danish Psychiatric Data on the autism project. Poul stated this was the registry based data on vaccines. He stated that permission should already be in place. (However, it would be confirmed later that no permissions were in place and that Thorsen had never applied for them.) [Pp. 18-19] [CJF emphasis]
Not only were the above lack of permissions going on, Clay says,
Marshalyn had more questions. She verified that there was no medical abstraction of the autism perinatal records. Carsten had not found original approvals and was looking to Poul to provide them. Carsten believed they did not have permissions for the autism disorder case control study. Poul suggested checking with Kristine. (Exhibit 40)
On the 30th of November 2009, Coleen Boyle, Diana Schendel, Marshalyn Yeargin-Allsopp colluded with Danish grantees to cover up a serious ethical violation in already published andabout to be published research. They sought to cover their tracks on their failure to ensure Poul Thorsen had obtained all the needed ethical approvals for the autism bio and genetic studies. Two studies were published in which legally required ethical permissions were apparently never applied for and granted according to their notes. When repeatedly asked to provide them, Thorsen did not.
In what are completely unethical acts by all involved, the team members went into damage control mode and decided that they likely could obtain permission for ongoing and future studies. They concluded that it would probably be impossible to get permission for research that was already finalized (and published). It is absurd that experienced federal grants management officials even discussed the idea of seeking a human subject safety review retroactively. These reviews, known as Institutional Review Boards (IRB) in the United States and Ethical Committees in Denmark are required before a study is initiated in order to protect patients and patient records from abuse. It would seem from the outset that the CDC was incompetent or inept in the management of this project. They also failed to do a site visit for the first three years. [CJF emphasis]
Collusion on the part of yet other CDC employees to commit fraud
How many times do we have to learn about a criminal collusion culture existing at the CDC/FDA before Congress, or whoever has proper oversight since Congress seems out-to-lunch, does anything to stop vaccine fraud?
Beth Clay ‘punctuates’ an apparent “Peter Principle” [2] promotion scheme within the CDC culture:
The Peter Principle is an observation that the tendency in most organizational hierarchies, such as that of a corporation, is for every employee to rise in the hierarchy through promotion until they reach the levels of their respective incompetence. [CJF emphasis]
Look what happened to Dr. Coleen Boyle!
Dr. Coleen Boyle, who has since been promoted to be Director of NCBDDD at CDC should have shut this grant down immediately upon being informed that ethical clearances were not in place. She should have immediately contacted the Office of Research Integrity, potentially even the Office of Inspector General. Funding should have been discontinued. She should have led the charge to have these papers retracted. There should have been, at a minimum, a press release from the CDC to inform the public. Instead, Dr. Boyle along with Dr. Marshalyn Yeargin-Allsopp, Joanne Wojcik and Dr. Diana Schendel colluded with their Danish Grantees to ‘fix it’ and retrospectively apply ethics approvals. Their next call on 14 December 2009 closed the case on Poul providing information to Aarhus. Joanne and Diana determined to go back through older grant applications to search for permissions.
Not only is this an egregious cover up, but it also points to poor grant management by CDC staff. The CDC staff responsible for this multimillion dollar grant, starting with Diana Schendel, should have had copies of all the legally required ethics permissions in hand before the Danish grantees were allowed to get started and before the first US taxpayer dollar was sent to Denmark. [CJF emphasis]
The Clay update on Thorsen is worth reading to understand how ‘legal sleight of hand’ goes on in federal bureaucracies and agencies where unelected bureaucrats apparently become ingrained and accepted culture ‘denizens’, knowing the CDC ‘has their backs’ (a la William Thompson, PhD’s whistleblowing [3]) and they will not be held accountable.
Well, Robert F. Kennedy Jr. apparently thinks differently and has shifted his attention to getting Poul Thorsen extradited to the U.S. to “face the music” and “pay the piper” for misappropriating between One and Two Million Dollars in CDC grant money.
However, who will make whole ASD children and their families as a result of Thorsen’s and other CDC researchers’ fraudulent work stating no association between Autism and vaccines, when in fact, there IS?
Catherine J Frompovich (website) is a retired natural nutritionist who earned advanced degrees in Nutrition and Holistic Health Sciences, Certification in Orthomolecular Theory and Practice plus Paralegal Studies. Her work has been published in national and airline magazines since the early 1980s. Catherine authored numerous books on health issues along with co-authoring papers and monographs with physicians, nurses, and holistic healthcare professionals. She has been a consumer healthcare researcher 35 years and counting.
The reason I post information about vaccines to Lyme/MSIDS patients is you are confronted on nearly a daily basis to get the poke, and if you are like any normal person this confrontation will leave you feeling guilty if you don’t sprint to your local pharmacy for the latest “free” vaccine.
Please know that similarly to the Lyme controversy, there is a very real vaccine controversy with more and more medical practitioners speaking out about the very real concerns for safety, efficacy, and implications. This is true for everyone, but particularly for those who are chronically ill with a pathogen invasion of the worst kind. Please be informed and take the time to learn about the debate just as you learn about the debate on Lyme/MSIDS. LLMD’s believe autoimmunity plays an important role in Lyme/MSIDS. No one knows what part vaccinations play in a chronically ill person who already has autoimmunity.
Dr. Suzanne Humphries July, 2017,
Approx. 5:30 Min
The Real Reason Aluminum is in Vaccines
Injecting Aluminum Official Trailer Approx. 2:30
https://madisonarealymesupportgroup.com/2017/09/19/autism-aluminum-adjuvant-link-corroborated/ Dr. Christopher Shaw and colleagues have established convincing biological evidence linking aluminum adjuvant used in vaccines to autism. “This is the paper I have been waiting for. This paper reports measurements of cytokines in the brains of animals injected with aluminum adjuvant as neonates. The same cytokines are elevated as in human autism. IL-6 and CCL2/MCP-1 are elevated for example. Male animals are more strongly affected. It’s a perfect match to human autism.”
Flawed assumptions fuel autoimmune disease: The Sorry State of Vaccine Safety Science Infection, Vaccination and Autoimmune disease
Wraith et al.1 observe that there is a high probability that microbial antigens can induce cross-reactive immune responses against self-antigens. They explain that we have evolved fail-safe mechanisms that usually protect us from developing autoimmune disease following infections.
They write: “Here we analyse our understanding of how infections can lead to autoimmune disease and thus assess the relative risk of autoimmune disease arising as a consequence of vaccination.” and “These fail-safe mechanisms apply equally to the host response to vaccination. ”
Mojsilovic2 writes: “Moreover, one must not overlook the fact that vaccines only mimic natural infections, and infectious agents themselves can elicit the same immune phenomena. Indeed, the risk of developing immunemediated diseases by acquiring natural infection is even greater than the risk of the same diseases to develop by vaccine- associated reactions.”
Unfortunately, neither Wraith et al. nor Mojsilovic, provide any explanation, evidence or reference to literature supporting this fundamental assumption that fail-safe mechanisms operative during infections are active during host response to vaccination.
This fundamental assumption is easily demonstrated to be false. Live attenuated influenza vaccine (LAIV, Flumist) and live oral rotavirus vaccines come closest to natural infection and have routes of administration that match natural infection. So the immune pathways triggered may be similar. Even so, considering that the vaccines do not cause disease, one cannot guarantee that all immune pathways triggered by natural infection are also triggered by the vaccine. So the autoimmune fail-safe mechanisms cannot be assumed to have been operational.
Many vaccines administered today are subunit vaccines. They are administered through intramuscular or subcutaneous routes. Neither matches the route of natural infection. So they trigger different immune pathways. Subunit vaccines primarily contain one or more antigens from the target organism. These antigens are poorly immunogenic and the host response is weak. This weak immune response is part of the autoimmune fail-safe mechanism at work.
To make the vaccine work, adjuvants such as aluminum salts or toxoids are needed to boost the immune response. In other words, adjuvants, by definition, defeat the fail-safe mechanism.
Mojsilovic writes: “The main role of adjuvants is to trick the immune system in perceiving vaccine antigen as a serious threat, and thus initiate innate and consecutively adaptive response mechanisms, including long-term immune memory to that antigen.”
This artificial immune response was NOT engineered to mimic a natural infection. It was a serendipitous discovery (immunology’s dirty secret), tuned empirically3,4. The mechanisms of action involved in an adjuvant induced response is still not understood and is an active area of research. So there is no scientific basis to make the claim that the natural autoimmune fail-safe mechanisms are operational in the case of adjuvanted subunit vaccines either.
Fever is common during natural infections5 . Fever is rare with subunit vaccines6 . Even the rare vaccine induced fever is suppressed with the (controversial and changing) recommendation of using acetaminophen following vaccination, to overcome injection site pain. Acetaminophen may affect inflammatory pathways.7,8 Fever impacts immune system behavior including IL-6 and heat shock protein related pathways5 . Clearly, natural infection and vaccines DO NOT produce the same immunological effect. Therefore autoimmune fail-safe mechanisms operational during natural infection, CANNOT be assumed to be operational during a vaccine-induced host response. So, the Wraith et al. observation that there is a high probability that microbial antigens can induce crossreactive immune responses against self-antigens, needs serious consideration in the context of vaccines. And we see strong evidence of vaccines inducing numerous autoimmune diseases.9–17
In Biotechnology and Safety Assessment (2003)18, immunotoxicology expert Dr. François Verdier with vaccine maker Aventis Pasteur (now Sanofi Pasteur), writes: “Helicobacter pylori catalase was excluded from the screening of vaccine antigens because first it showed sequence homology with human catalase and second human catalase is reported to be an autoantigen in inflammatory bowel disease”
If Wraith et al. were right about “These fail-safe mechanisms apply equally to the host response to vaccination. “, an H. pylori catalase vaccine should have the same risk of causing autoimmune disease as the H. pylori infection. But as Dr. Verdier points out, the H. pylori catalase vaccine was considered unsafe and was excluded.
But unfortunately, numerous other vaccines contaminated with catalase, were inexplicably approved and are in widespread use.19 This can explain the epidemic of inflammatory bowel disease.
Tricking the immune system gets tricky
We understand very little about the immune system but we have decided to trick it. It is not a story you expect to end well.
Mojsilovic writes: “The main role of adjuvants is to trick the immune system in perceiving vaccine antigen as a serious threat, and thus initiate innate and consecutively adaptive response mechanisms, including long-term immune memory to that antigen.”
Vaccines are of course contaminated with non-target viral, bacterial antigens, numerous growth media proteins including casein, ovalbumin, yeast, bovine serum albumin etc.20 Example: the Pandemrix vaccine contained influenza hemaggluttinin proteins (target) and influenza nucleoproteins (contaminant).16
By tricking the immune system into perceiving ALL of the above proteins as a serious threat, adjuvants predictably produce numerous off-target immune responses such as food allergies21, asthma22 and disable the autoimmune fail-safe mechanism, producing autism11,23 and other autoimmune disorders19 .
The fact that adjuvanted vaccines work is proof that they create allergy and autoimmune diseases as well. This is a fundamental flaw in current vaccines.
Vaccine safety recommendations are ignored
Wraith et. al. call for autoimmune serology during vaccine trials. Vaccine trials have ignored that recommendation. No autoimmune serology is performed during vaccine trials.6,24–26 .
Serology is used only to check titers of antibodies against the target antigen. Checking for other antibodies such as IgE and IgG4 against self and contaminating antigens could easily identify vaccine-induced allergies, asthma, autism and autoimmunity.10,27–30
The fact that Pandemrix induced narcolepsy was only discovered after sickening numerous patients is proof that safety mechanisms required during vaccine design and testing, to avoid autoimmune diseases, are absent or dysfunctional.
Wraith et al. say autoimmune disease manifestation takes years. Yet vaccine trials last a few months. And post-marketing manifestation is easily dismissed with the statement: “Because these events were reported voluntarily from a population of uncertain size, it is not possible to reliably estimate their frequency or to establish a causal relationship to vaccine exposure.”31
Adjuvant and vaccine safety claims are premature
Vaccines and the adverse events they induce can be separated by decades.
In one mechanism, vaccine induced autoantibodies in women, attack the fetal brain and cause autism.11 With decades between vaccine induced autoantibodies and the adverse event affecting a different individual than the one vaccinated, there is no chance that vaccine surveillance mechanisms will ever find this type of adverse event or help in determining root cause.
This is the fundamental limitation of the “safety by testing” methodology. We need “safety by design”. Testing should be used to catch design errors. But current vaccines are empirically derived using trial and error. The result is fundamentally unsafe vaccines.
Mojsilovic: “Some of the first adjuvants discovered back then, on empirical basis of trial and error, are still in widespread use today, but only recently some light on the molecular mechanisms of their action has been shed.”
Immunological effects of current adjuvants were not designed. They are empirical, trial and error based. So no claim can be made that autoimmune fail-safe mechanism operative during natural infection are active during adjuvanted vaccine driven immune responses.
Diseases like cerebral infarction (CI), diabetes mellitus (DM), cardiovascular diseases (CVD) develop over the long-term due to inflammation32. There is evidence that they may have an autoimmune basis12,33. These diseases may been caused by aluminum adjuvanted vaccines decades ago. So the safety claims being made for aluminum adjuvants or vaccines are premature. The real cause and autoimmune basis of these adverse events is just surfacing now.
The autoimmune basis of many diseases are still being elucidated and researched.9,34–39. How can we rule out aluminum adjuvant and/or vaccines being the causative agent? It is therefore premature to make any claim about the safety of aluminum adjuvants or vaccines.
Tissue damage
Wraith et al. “Based on first principles, one could argue that a killed vaccine would be less likely than a liveattenuated vaccine to activate the innate immune response or cause tissue disruption.”
Not true. A live-attenuated influenza vaccine can at least be administered without tissue disruption. On the other hand, killed or subunit vaccine administration through intramuscular or subcutaneous routes involve tissue disruption. Vaccine antigens mimicking self antigens being present in the vicinity of tissue damage is therefore a very common occurrence with current vaccines. So the risk of autoimmune disease induction is greater with killed or subunit vaccines.
Further, killed or subunit vaccines are poorly immunogenic. As Mojsilovic points outs, “Adjuvants do that by triggering the same evolutionary conserved mechanisms that innate immunity utilizes to detect danger. By inducing innate immune reaction, adjuvants can concurrently provoke some undesirable immune response”. Even if the killed or subunit vaccines by themselves were less likely to activate the innate immune response or cause tissue disruption as Wraith et al. claim, the adjuvant used to fix the problem of poor immunogenicity, works by activating the innate immune response and causing tissue damage.40
Intramuscular or subcutaneous vaccine administration results in tissue damage due to the injection itself and further tissue damage caused by adjuvants. This results in Danger Associated Molecular Pattern (DAMP) receptor signals being asserted. Next, vaccine antigens trigger Pathogen Associated Molecular Pattern (PAMP) receptor signals. With natural infection, the signaling is reversed. The pathogen is detected before any tissue damage occurs. Any tissue damage due to infection and associated DAMP signaling follows. This is another difference between vaccines and natural infection. What effect does this have on the immune response and the autoimmune fail-safe mechanism?
Atopy and autoimmune disease
Wraith et al. state that atopy is unrelated to autoimmunity. Again they provide no references. This is an incorrect notion. We know that IgE antibodies are created to just about every type of protein that is injected.41,42 Once sensitized to IgE, we know that prolonged exposure to the antigen causes the synthesis of IgG4 to the same antigen.43–46 We know that one cause of autism is folate receptor alpha autoantibodies (FRAA)34,36. A majority of FRAA are of the IgG4 isotype.36 Many vaccines are contaminated with cow’s milk that contains the folate receptor protein. So we have an example of atopy, where induction of IgE to folate receptor proteins in milk contaminated vaccines is the first step in an autoimmune disease. Continuing exposure to dietary milk results in the induction of IgG4 autoantibodies causing this type of autism which is an autoimmune disease.47
So there are no clear delineations between atopy and autoimmune diseases.
Similarly, injection of yeast (Saccharomyces cerevisiae) contaminated vaccines can be expected to cause IgE mediated sensitization. Atopic dermatitis patients react to S. cerevisiae.48,49 Subsequent prolonged exposure to yeast will result in IgG4 induction.50 Many autoimmune diseases are associated with anti-saccharomyces cerevisiae autoantibodies (ASCA)51–53,9 .
Pertussis vaccine and autoimmune disease
The FDA made the flawed assumption that the acellular pertussis vaccine prevented transmission of disease, when they approved the vaccine. The acellular pertussis vaccine does not prevent transmission. The vaccine does not provide mucosal immunity.54 Vaccinated individuals are colonized by B. pertussis and spread the disease to infants too young to be vaccinated.55 This B. pertussis airway colonization has been linked to multiple sclerosis, an autoimmune disorder.54 To protect neonates against pertussis via passive immunity, the Advisory Committee on Immunization Practices (ACIP) has recommended the Tdap vaccine for every pregnant woman. However, this increases the risk of autoimmune responses against the fetus.11,47
Vaccines are assumed safe until proven otherwise
The Infanrix vaccine package insert says: “The role of the different components produced by B. pertussis in either the pathogenesis of, or the immunity to, pertussis is not well understood.”6
The Flumist flip-flop by the ACIP, is more evidence that vaccines are poorly understood. So it makes no sense to assume that vaccines are safe until proven otherwise. Instead, with vaccines being powerful immunomodulatory interventions, we MUST assume that vaccines are unsafe until proven otherwise. Here’s an example of the unintended consequences. The pertussis vaccine enables subclinical colonization by B. pertussis. The consequences of colonization include Alzheimer’s disease. 56
In the WHO methodology described by Wraith et al. Vaccines are assumed safe until proven otherwise. This does not make any sense. With widespread molecular mimicry between vaccine antigens, contaminants and self antigens, vaccines can impact numerous functions in the human body. Therefore, if any disease occurs after vaccine administration, vaccines MUST be assumed to be the cause unless one can prove otherwise.
The only way to ensure that all the immune pathways required for natural autoimmune fail-safe mechanisms are triggered is to make the vaccine produce the disease. Therefore any useful vaccine cannot be guaranteed to trigger the autoimmune fail-safe mechanisms. Therefore, all vaccines must be considered autoimmune disease causal agents unless proven otherwise. The WHO approach of assuming vaccines are safe until proven otherwise is wrong and unsupported by scientific evidence.
The bar for vaccine safety has been set too low.
The scientific process has failed
Peer review has failed to identify these problems that have continued to persist for decades with devastating consequences. In the case of the acellular pertussis vaccine, reality’s rude awakening in the form of pertussis infections, at least led to the FDA/CDC acknowledging the problem.
Theory vs. Practice
Mojsilovic on an advantage of adjuvants:
“… including the possibility to restrict the number of antigens present in a vaccine, and thus further reduce any risk of undesired (cross-reactive) immune responses to self tissues.”
Pandemrix was adjuvanted but the manufacturer failed to restrict the number of antigens thus triggering narcolepsy. So a theoretical advantage of adjuvants backfired in practice due to a sloppy vaccine design. Coupled with sloppy vaccine testing which was not designed to catch such problems, the consequences were devastating.
Regulatory failure
Mojsilovic: “By carefully monitoring the rare adverse events and scrupulously studying their mechanism of development, regulatory agencies, vaccine manufacturers, and researchers are participating in a joint endeavor to identify the specific factors that contribute to these events and to develop even safer vaccines.”
Mojsilovic: “there are carefully elaborated regulatory mechanisms to ensure that risks of such adverse reactions are kept at minimum.”
Unfortunately, Mojsilovic cites no references to support these claims.
How can one assume that adverse events are rare? It may be as common and widespread as obesity or atherosclerosis caused by vaccine-induced autoantibodies.12,16,57,33 If above claims by Mojsilovic are true, why did Pandemrix induce narcolepsy? Why no autoimmune serology in clinical trials, as suggested by Wraith et al.? Wraith et al.
“Criteria underpinning the assessment of adverse events of vaccines have been established by the WHO”
But WHO has no criteria for designing vaccines to avoid autoimmune diseases in the first place?
Vaccine risk vs. disease risk
Wraith et al. “However, the degree of vaccine-related risk should always be compared with that associated with the corresponding natural infection, either for the whole population or for a specific subgroup.”
The touted benefit of a vaccine is the avoidance of natural infection and its sequelae. So it is unacceptable for a vaccine to have the same risk of autoimmune disease as the natural infection. Depending on the disease, natural infection may be rare (say tetanus). But everyone is going to get a tetanus vaccine, multiple times. This increased exposure must be accounted in risk evaluation.
Wraith et al. “potential molecular and immunological mimicry between vaccine antigens and host components should be extensively analysed through a combination of bioinformatics and immunological studies.”
Never happens. Pandemrix induced narcolepsy could have been avoided if this homework was done.17 Where are studies establishing safety of these cases of mimicry?11–16
Accounting for antigen exposure dependent autoimmune disease
Autoimmunity caused by molecular mimicry to food antigens could result in severe illness due to ongoing exposure to food antigens. An example of this is cow’s milk contaminated vaccines inducing folate receptor autoantibodies that block folate receptors and cause autism spectrum disorders.34,47 A milk-free diet reduces autism symptoms.34,58 Similarly, vaccine induced autoimmunity caused by molecular mimicry to bacterial or viral antigens could be transient and only manifest itself upon re-exposure to that bacteria or virus. Studies that don’t account for such details will come to the wrong conclusion.
Conclusion
Whitaker et al.59 write: “the promise of adversomics is to understand the mechanisms behind vaccine adverse events in order to improve vaccine safety”
200 years after Dr. Jenner’s vaccines, understanding the mechanisms behind vaccine adverse events remains a novel concept? Proof that root cause analysis is an alien concept in vaccine research and industry.
Whitaker et al. write: “If vaccine adverse events are noted, then further studies will need to be conducted to determine whether the adverse event is related to the adjuvant, to the antigens in the vaccine, or to an adjuvantantigen combination.”
Applying that statement to aircraft, accentuates the absurdity:
“If air crash occurrences are noted, then further studies will need to be conducted to determine whether the crash is related to the engine, to the airframe of the aircraft, or to an engine-airframe combination.”
Explains why Pandemrix caused narcolepsy. If “further studies” can be performed, you don’t wait for people to get hurt but you should perform them before the product hurts people.
With little root cause analysis, little design for safety, the vaccine industry has been stuck tinkering with trial and error for over 200 years. The devastating consequences are predictable. This is no way to build a product that has such an enormous impact on people’s lives. It is doubtful if any other safety critical industry can get away with such a callous disregard for human safety.
References
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4. Gayed PM. Toward a modern synthesis of immunity: Charles A. Janeway Jr. and the immunologist’s dirty little secret. Yale J Biol Med. United States; 2011 Jun;84(2):131–8.
5. Evans SS, Repasky EA, Fisher DT. Fever and the thermal regulation of immunity: the immune system feels the heat. Nat Rev Immunol. 2015 Jun 15;15(6):335–49.
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9. Rinaldi M, Perricone R, Blank M, Perricone C, Shoenfeld Y. Anti-saccharomyces cerevisiae autoantibodies in autoimmune diseases: From bread baking to autoimmunity. Clinical Reviews in Allergy and Immunology. 2013. p. 152–61.
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New Canadian study: Autism-Aluminum adjuvant link corroborated
BY J.B. HANDLEY September 18, 2017
In the December 2017 issue of the Journal of Inorganic Biochemistry and released online today, Dr. Christopher Shaw and colleagues at the University of British Columbia have established convincing biological evidence linking aluminum adjuvant used in vaccines to autism.
“This is the paper I have been waiting for.This paper reports measurements of cytokines in the brains of animals injected with aluminum adjuvant as neonates. The same cytokines are elevated as in human autism. IL-6 and CCL2/MCP-1 are elevated for example. Male animals are more strongly affected. It’s a perfect match to human autism.”
VANCOUVER, British Columbia — Just two weeks ago, I wrote about a study from France that raised major concerns about aluminum adjuvant used in vaccines. The French study authors wrote: “Concerns about its [aluminum adjuvant’s] safety emerged following recognition of its unexpectedly long-lasting biopersistence within immune cells in some individuals, and reports of chronic fatigue syndrome, cognitive dysfunction, myalgia, dysautonomia and autoimmune/inflammatory features temporally linked to multiple Al [aluminum]-containing vaccine administrations.”
In a nutshell, the French study found that when smaller doses of aluminum adjuvant were consistently injected over a short period of time — like during childhood vaccinations —the aluminum was more likely to end up in the brain, and the French scientists issued a stern warning about the use of aluminum adjuvant in vaccines:
In the context of massive development of vaccine-based strategies worldwide, the present study may suggest that aluminium adjuvant toxicokinetics and safety require reevaluation.
Canadian researchers establish direct link
In the December 2017 issue of the Journal of Inorganic Biochemistry and released online today, Dr. Christopher Shaw and colleagues have established convincing biological evidence linking aluminum adjuvant to autism. The study’s title alone should cause concern for parents everywhere:
“It thus appears that Al [aluminum adjuvant] triggered innate immune system activation and altered cholinergic activity in male mice, observations which are consistent with those in autism. Female mice were less susceptible to Al exposure as only the expression levels of NF-κB inhibitor and TNFA were altered. Regional patterns of gene expression alterations also exhibited gender differences, as frontal cortex was the most affected area in males and cerebellum in females. Thus, Al adjuvant promotes brain inflammation and males appear to be more susceptible to Al′s toxic effects.”
It’s critical to note that the researchers found gender differences in how the mice responded, with male mice showing higher susceptibility, which is consistent with what we are seeing in autism: roughly 80% of the cases are boys.
The Canadian researchers included a diagram in their study that showed how aluminum adjuvant can contribute to an inflammatory cascade in the brain that leads to autism.
What does this mean in plain English?
Six months ago, I wrote an article about how close it appeared international scientists were to establishing a clear biological basis for how aluminum adjuvant can create autism. My article has been read more than 250,000 times, and I have heard from scientists from all over the world (most unwilling to let me quote them in public, which is its own great tragedy), including a scientist who has created a great website called Vaccine Papers. I asked “VP” about the importance of this study, and words were not minced:
This is the paper I have been waiting for.
This paper reports measurements of cytokines in the brains of animals injected with aluminum adjuvant as neonates. The same cytokines are elevated as in human autism. IL-6 and CCL2/MCP-1 are elevated for example. Male animals are more strongly affected. It’s a perfect match to human autism.
The paper includes a number of strong statements about vaccine causality.
This paper is hugely important because it shows IL-6 elevation in the brain, which of course provides a firm link to the immune activation literature. It is strong evidence supporting the al adjuvant IL-6 autism hypothesis.
Vaccines are given to babies during key phases of brain development
A Clear Hypothesis
If you would like to understand this complex issue in greater detail, I hope you will consider reading my widely read article from six months ago:
For the sake of brevity, here are the four key scientific discoveries I discussed in this lengthy article, most of which has happened in the last thirty-six months, appearing to show a clear link between aluminum adjuvant from vaccines and autism.
Discovery #1: “Maternal Immune Activation” can cause autism
Some helpful quotes from the above research to help contextualize Discovery #1:
“As we learn more about the connections between the brain and the immune system, we find that these seemingly independent networks of cells are, in fact, continually talking to each other. As an adult, the activation of your immune system causes many striking changes in your behavior — increased sleep, loss of appetite, less social interaction — and, of course, headaches. Conversely, stress in your life (as perceived by your brain) can influence immune function — the brain regulates immune organs, such as the spleen, via the autonomic nervous system.
Recent evidence shows that this brain-immune conversation actually starts during the development of the embryo, where the state of the mother’s immune system can alter the growth of cells in the fetal brain. As we shall see, such alterations can lead to an increased risk of schizophrenia or autism in the offspring.” — Dr. Paul Patterson, CalTech
Dr. Paul Patterson, CalTech
“There is also very striking evidence of immune dysregulation in the brain itself. Just last year, a group led by Carlos Pardo at Johns Hopkins found what they’re calling a “neural inflammation” in postmortem examination of brains of patients with autism who died between the ages of eight and 44 years. But these people weren’t infected — they died of such things as drowning or heart attacks. The study found that the microglial cells, which act as the brain’s own immune system, were activated. The study also found amazing increases of certain cytokines in the brain, and of others in the cerebro- spinal fluid. This is is a landmark paper, in my opinion. It presents the first evidence that there’s an ongoing, permanent immune-system activation in the brains of autistic people. It’s a subclinical state, because there’s no overt infection. But it’s there.” — Dr. Paul Patterson, CalTech
“In conclusion, the present PET measurements revealed marked activation of microglia in multiple brain regions of young adults with ASD. The results strongly support the contention that immune abnormalities contribute to the etiology of ASD.” — Dr. Carlos Pardo, Johns Hopkins
“Cytokines are produced by the white blood cells, and their levels in the blood increase when we get an infection…We think that maternal immune activation alters brain circuits…there’s that permanent, subclinical, altered immune state in the autistic brain — those increased cytokine levels…are they [cytokines] actually interacting with the brain in an ongoing fashion, with consequences visible in the patients’ behavior? I favor [the cytokine] hypothesis.” — Dr. Paul Patterson, CalTech
“Here we show that the cytokine interleukin-6 (IL-6) is critical for mediating the behavioral and transcriptional changes in the offspring. A single maternal injection of IL-6 on day 12.5 of mouse pregnancy causes prepulse inhibition (PPI) and latent inhibition (LI) deficits in the adult offspring.” — Dr. Paul Patterson, CalTech
“In this rhesus monkey model, MIA yields offspring with abnormal repetitive behaviors, communication, and social interactions. These results extended the findings in rodent MIA models to more human-like behaviors resembling those in both autism and schizophrenia.” — UC Davis MIND Institute
“In summary, our study supports a critical role of IL-6 elevation in modulating autism-like behaviors through impairments on synapse formation, dendritic spine development, as well as on neuronal circuit balance. These findings suggest that manipulation of IL-6 may be a promising avenue for therapeutic interventions.” —Dr. Xiaohong Li, Shanghai Jiao Tong University School of Medicine
Discovery #2: Aluminum Adjuvant causes immune activation and is far more neurotoxic than previously thought
Some helpful quotes from the above research to help contextualize Discovery #2:
“In addition, the continued use of aluminum adjuvants in various vaccines (i.e., Hepatitis A and B, DPT, and so on) for the general public may have even more widespread health implications. Until vaccine safety can be comprehensively demonstrated by controlled long-term studies that examine the impact on the nervous system in detail, many of those already vaccinated as well as those currently receiving injections may be at risk in the future. Whether the risk of protection from a dreaded disease outweighs the risk of toxicity is a question that demands urgent attention.” — Dr. Christoper Shaw, University of British Columbia
“Overall, the results reported here mirror previous work that has clearly demonstrated that aluminum, in both oral and injected forms, can be neurotoxic. Potential toxic mechanisms of action for aluminum may include enhancement of inflammation (i.e., microgliosis)…” — Dr. Christoper Shaw, University of British Columbia
“…it is somewhat surprising to find that in spite of over 80 years of use, the safety of Al adjuvants continues to rest on assumptions rather than scientific evidence.For example, nothing is known about the toxicology and pharmacokinetics of Al adjuvants in infants and children…Yet, in spite of these observations children continue regularly to be exposed to much higher levels of Al adjuvants than adults, via routine childhood vaccination programmes.” — Dr. Lucija Tomljenovic, University of British Columbia
“However, continuously escalating doses of this poorly biodegradable adjuvant in the population may become insidiously unsafe, especially in the case of overimmunization or immature/altered blood brain barrier…” —Dr. Josette Cadusseau, Université Paris
“Thus alum and other poorly biodegradable materials taken up at the periphery by phagocytes circulate in the lymphatic and blood circulation and can enter the brain using a Trojan horse mechanism similar to that used by infectious particles. Previous experiments have shown that alum administration can cause CNS dysfunction and damage, casting doubts on the exact level of alum safety.” — Dr. Josette Cadusseau, Université Paris
“We conclude that Alhydrogel [aluminum adjuvant] injected at low dose in mouse muscle may selectively induce long-term Al cerebral accumulation and neurotoxic effects. To explain this unexpected result, an avenue that could be explored in the future relates to the adjuvant size since the injected suspensions corresponding to the lowest dose, but not to the highest doses, exclusively contained small agglomerates in the bacteria-size range known to favour capture and, presumably, transportation by monocyte-lineage cells. In any event, the view that Alhydrogel neurotoxicity obeys ‘the dose makes the poison’ rule of classical chemical toxicity appears overly simplistic.” —Dr. Romain K. Gherardi, Université Paris Est Créteil (UPEC)
“In the context of massive development of vaccine-based strategies worldwide, the present study may suggest that aluminium adjuvant toxicokinetics and safety require reevaluation.” — Dr. Romain K. Gherardi, Université Paris Est Créteil (UPEC)
Discovery #3: Aluminum can increase IL-6 in the brain
Some helpful quotes from the above research to help contextualize Discovery #3:
“The results also showed that aluminum administration increased the hippocampus pro-inflammatory cytokines TNF-α by 3.8-fold, IL-6 by 4-fold, and iNOS by 3.8-fold compared to the normal control group.” —Dr. Mosaad A. Abdel-Wahhab, Cairo University
Most vaccines contain aluminum, and aluminum is a proven neurotoxin, in amounts received from vaccines. Vaccines in combination can result in toxic aluminum overload. Even the aluminum in a single vaccine can be harmful because the aluminum is in a form that is more dangerous than ingested aluminum. Specifically, vaccine aluminum is in nanoparticulate form, which is harder for the body to eliminate, and because it is transported around the body differently than ingested aluminum.
It is natural and normal to ingest small doses of aluminum from food and water. Its not good for you, but the body has adequate defenses. Absorption of ingested Al is low, about 0.3%, so about 99.7% is eliminated in feces. Ingested aluminum is in ionic form (individual charged atoms), which is readily removed by the kidneys. Also, ionic aluminum is blocked from entering the brain by the blood brain barrier. The low absorption, rapid elimination by the kidneys and barrier to brain entry adequately protects the brain from aluminum.
However, nanoparticulate aluminum from vaccines cannot be removed by the kidneys. The particles are far too large to be filtered out by the kidneys. The Al nanoparticles do dissolve slowly (converting to ionic aluminum). But long before they can dissolve completely, the Al nanoparticles are “eaten” by immune system cells called macrophages. In other words, the particles wind up inside the macrophages. Once loaded with the Al nanoparticles, the macrophages spread aluminum as they travel through the body. This is dangerous, because the Al-loaded macrophages carry Al nanoparticles to tissues (e.g. the brain) that are damaged by very small amounts of aluminum. — Vaccine Papers
“Here we show that mice with elevated IL-6 in the brain dis- play many autistic features, including impaired cognitive abilities, deficits in learning, abnormal anxiety traits and habituations, as well as decreased social interactions. IL-6 elevation caused alterations in excitatory and inhibitory synaptic formations and disrupted the balance of excitatory/inhibitory synaptic transmissions. IL-6 elevation also resulted in an abnormal change in the shape, length and distributing pattern of dendritic spines. These findings suggest that IL-6 elevation in the brain could mediate autistic-like behaviors, possibly through the imbalances of neural circuitry and impairments of synaptic plasticity.” —Dr. Xiaohong Li, Shanghai Jiao Tong University School of Medicine
Discovery #4: Hepatitis B vaccine induces IL-6 in postnatal rats
Studies that support Discovery #4:
[Author’s note: This fourth discovery was really the subject of my extensive article, because it discussed a new paper that seemed to tie everything together. The Canadian paper above ties everything together even more tightly.]
Some helpful quotes from the above research to help contextualize Discovery #4:
“An important new study by Li et al. reports the effects of bacillus calmette-guerin (BCG) vaccine (for tuberculosis) and hepatitis B vaccine on brain development in infant rats. The study relates the observed brain changes to the type of immune activation (Th1 or Th2, explained below) stimulated by the vaccines. The BCG and hep B vaccines had opposite effects on the brain (BCG being beneficial, and hep B being detrimental), and a combination of both vaccines resulted in cancellation of the effects.
This is the first study to test the effects of immune activation by vaccination on brain development. All other studies of immune activation have used essentially pathological conditions that mimic infection and induce a strong fever. A criticism I have heard often from vaccine advocates is that the immune activation experiments are not relevant to vaccines because vaccines cause a milder immune activation than injections of poly-IC or lipopolysaccharide (two types of immune system activators).
This new study demonstrates that vaccines can affect brain development via immune activation. Hence, the immune activation experiments are relevant to vaccines…The hep B vaccine increased IL-6 in the hippocampus (the only brain region analyzed for cytokines).” — Vaccine Papers
Four discoveries, a clear path to autism
Here’s a simple graphic that I think spells out the process of triggering autism very clearly, as demonstrated by the published science I have shared with you above through the four discoveries.
The new Canadian study, just published, makes these findings even more clear, and more robust, and provides even greater detail into HOW aluminum adjuvant leads to autism.
Image created by Vaccine Papers.org
Now what?
When I published my article back in February, I heard from scientists from all over the world. I heard from pediatricians. I heard from board members at Autism Speaks. Many agreed with me: this was disturbing and important work, and it may well describe where all this autism is coming from. What’s happened since that time? Nothing.
There’s no mechanism for reviewing or putting all this published science together. The scientists doing this great work are perpetually nervous that they will lose their funding source or get “Wakefielded.” There’s no group responsible for putting all these published scientists in a room and figuring out what we do about this giant mess, and what all this information means. Every minute, a new child is diagnosed with autism, and every minute, it strikes me that autism may be completely AVOIDABLE. If you’re reading this, all I can ask is that you share the information widely, and that if you happen to be in a position of influence, please help save our kids.
In my opinion, we are much, much closer to understanding how autism has been triggered in so many children, and I hope this article is another step on the path to the truth. And, for so many of you out there doing everything you can to help you son or daughter with autism live the best possible life, perhaps a clearer understanding of how their autism was triggered will improve their chances for recovery.
I’m posting this because it should be important to everyone; however, whenever you talk about the immune system and cytokines, Lyme/MSIDS patients should sit up and take notice. Due to a pathogen storm, we have a cytokine storm, confusing our immune systems and giving us boatloads of pain among other horrific symptoms. This is also a sound warning about receiving any vaccinations while infected as they are designed to introduce many foreign substances into the body so the body mounts a response. Our immune systems are already confused by a pathogen invasion. In fact, the question truly begs to be asked, are vaccines ever safe for infected patients? Also, it is important to point out that it is believed that children can get infected congenitally, which means they come out of the shoot compromised. What does vaccination do to them?
So much is unknown and unproven. Our children are too important not to search out the answers as inconvenient as they may be.
Every Lyme/MSIDS patient I know has regressed after a vaccination. Food for thought.
Immunization of mice with Borrelia burgdorferi lp54 gene encoded recombinant proteins does not provide protection against tick transmitted infectious challenge
The Borrelia burgdorferi outer surface membrane proteins BBA65, BBA66, BBA69, BBA70, and BBA73 were tested for their ability to confer protection against B. burgdorferi infection challenge. Mice were immunized with recombinant forms of the proteins singly or in combinations. Following initial protein inoculation and booster injections, seroconversion was confirmed prior to B. burgdorferi challenge by tick bite. Despite mice having high antibody titers for each antigen, no significant protections against the challenge infections were observed. These results demonstrate that these recombinant proteins were not protective and reflects the challenges confronted to identify effective novel vaccine candidates for Lyme disease.
Madison Area Lyme Support Group 