Archive for the ‘Transmission’ Category

Risk of Transmission of Bartonella via Blood Transfusion – Chile

https://www.ncbi.nlm.nih.gov/pubmed/29488546

Rev Chilena Infectol. 2017 Dec;34(6):539-543. doi: 10.4067/S0716-10182017000600539.

Prevalence of Bartonella henselae in blood donors and risk of blood transmission in Chile

[Article in Spanish]
Núñez MA1, Contreras K1, Depix MS1, Geoffroy E1, Villagra N2, Mellado S3, Salinas AM1.

Abstract
BACKGROUND:
Bartonella henselae is the causal agent of cat scratch disease in immunocompetent persons and bacterial angiomatosis in immunocompromised patients. In Chile, the prevalence of antibodies against B. henselae in healthy children and adolescents is 13.3%, in persons with occupational risk 60.5%, and in cats 85.6%. There are no published data regarding the seroprevalence in blood donors in our country, so determining if B. henselae is present in the blood of donors at the time of donation is very important, since this microorganism can survive up to 35 days in the red blood cells stored in a blood bank at 4 °C.

OBJECTIVE:
To determine the prevalence of B. henselae in blood donors.

METHODOLOGY:
140 donor blood samples were analyzed to detect the presence of B. henselae, using the polymerase chain reaction technique.

RESULTS:
13.6% of the blood donors with positive polymerase chain reaction for B. henselae were obtained. The sequence of the amplified fragments showed an identity of over 98% with respect to B. henselae reference sequences.

CONCLUSION:
The risk of blood transmission is due to a country with high B. henselae infection.

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**Comment**

Although this study is a year old, it’s the first time I’ve seen it.  It brings up a very important point in that Bartonella can be transmitted via blood transfusion, and not only in Chile, I might add.  Authorities are still bickering about whether or not it is transmitted via ticks, but there’s no denying many Lyme/MSIDS patients have Bartonella, which points strongly to it being transmitted by ticks.  

It is not a reportable disease so again, nobody truly knows the infection rates.  https://wwwn.cdc.gov/nndss/conditions/notifiable/2018/infectious-diseases/

Recently, Babesia, a reportable disease, is being screened for before a blood transfusion.  https://madisonarealymesupportgroup.com/2018/03/07/babesia-tests-approved-by-fda-for-screening-purposes

Bartonella is just as deadly & flies under the radar:  https://madisonarealymesupportgroup.com/2017/05/11/bartonella-henselae-in-children-with-congenital-heart-disease/

https://madisonarealymesupportgroup.com/2017/01/04/endocarditis-consider-bartonella/

https://madisonarealymesupportgroup.com/2018/03/09/bartonella-outbreak-in-homeless/

https://madisonarealymesupportgroup.com/2017/08/02/neurological-and-immunological-dysfunction-in-two-patients-with-bartonella-henselae-bacteremia/

https://madisonarealymesupportgroup.com/2018/03/04/bartonella-erythema-nodosum-atypical-presentations/

 

 

Asian Tick Found in New Jersey Can Kill Cattle by Draining them of Blood

http://www.businessinsider.com/ticks-from-asia-that-self-clone-found-in-us-2018-2?r=DE&IR=T

These invasive ticks can appear in such numbers that they drain cattle of their blood — and they’ve now been found in the US for the first time

Kevin Loria
Mar. 8, 2018

The tick in question is known in East Asia and has become a problem in New Zealand and Australia. Is it now in New Jersey?  Zheng et al, Korean Journal of Parasitology, 2011:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279682/

  • New Jersey health officials got an unpleasant surprise when they found a sheep infested with hundreds of ticks from an East Asian species that can clone itself.
  • The ticks are from the Haemaphysalis longicornis species, an invasive pest that has been known to appear in such numbers that they’ve killed cattle by draining them of blood.
  • The researchers are hoping that any remaining larvae died during the winter. If not, the species could become a problem.

New Jersey residents know they need to look out for ticks. The state has one of the highest concentrations of Lyme disease in the country.

But one recent finding could lead Garden State residents to keep an even closer eye out for the bloodsuckers than normal.

Somehow, an east Asian tick that has the ability to essentially clone itself and is a noted invasive species in other parts of the world made its way to Hunterdon County.

And it wasn’t just an isolated tick. There were more than 1,000 found in the western area of New Jersey.

The story began in August 2017, when a resident showed up at the Hunterdon County Health Department with samples of the ticks that had started crawling on her arm while she’d been shearing a sheep.

Health department officials noticed that the resident’s clothes were covered with the creatures, all tiny larval specimens.

“I get this call from my assistant and he said, ‘We’ve got a resident here who showed up covered in ticks; she’s panicking; now we’re panicking and her pants are in our freezer,'” Tadhgh Rainey, the head of the health department and lead author on a report documenting the incident, told NPR.

“Intense infestations”

The sheep’s ear alone had samples from all life stages of the tick.  Rainey et al, Journal of Medical Entomology, 2018:  https://academic.oup.com/jme/advancearticle/doi/10.1093/jme/tjy006/4840594

The researchers were able to tell that the ticks belonged to the Haemaphysalis genus, but the specimens didn’t match any known Western Hemisphere species. After further analysis, they identified the culprit: Haemaphysalis longicornis, a tick native to East Asia. The species can be parthenogenetic, meaning the ticks can reproduce asexually, essentially cloning themselves (this study provides more details on the unique reproductive processes of these particular ticks:  https://www.sciencedirect.com/science/article/pii/S0304401712002191?via%3Dihub).

Other regions of the world have had serious problems with this tick, which is capable of “intense infestations,” according to the study. Sometimes the insects have even killed animals by draining them of blood, a phenomenon known as exsanguination.

Isolated individual ticks of this species have been captured at border quarantine stations in the past, but this is the first known full-blown infestation in the US.

The infested “patient” in New Jersey was a 12-year-old Icelandic sheep.

Several department officials headed over to assess the animal, and as soon as they entered the paddock, ticks started to cover their pants.

The sheep itself had hundreds, in all three life stages — larva, nymph, and adult. The bugs covered its ears and face and had burrowed through its thick coat.

In one sample batch, the researchers only found one male, making it likely that this collection was a self-cloning one. The paddock was filled with larvae.

Several permethrin washes later, the sheep was found to be parasite free. After several visits, the paddock was eventually found to be tick-free on November 15 and 16. But the temperature had already dropped below freezing by then, and no one knows whether that killed the ticks or whether they just retreated into the soil, awaiting spring.

Questions and concerns

Are researchers going to need to add another tick to the list of species to look out for?

The big mystery is how the ticks got there. The sheep itself “had no history of travel outside the country,” the report authors noted. It hadn’t even traveled locally for a few years, and no other domestic animals live on the property.

There are, however, signs that deer and rabbits pass through the area. These ticks are known to infect similar animals, a fact that unfortunately opens the possibility that the pests could be lingering on other nearby creatures —and could start to spread.

“Ultimately there is great concern about the potential for an H. longicornis infestation in NJ, and this is being actively investigated, although the issue will likely not be settled before the spring of 2018, when any surviving ticks would exit diapause and begin host seeking,” the report’s authors wrote.

If these ticks are capable of surviving a Mid-Atlantic winter, that would be an unfortunate scenario. Not only are the pests capable of appearing in such numbers that they can literally drain animals of their blood, they can also bite people and carry disease.

In rural China, a bite from one of these ticks can spread an emerging hemorrhagic fever that can be deadly. These ticks are also known to carry diseases like Anaplasma, Ehrlichia, Borrelia, and a form of spotted fever, according to the study. Some researchers have suggested that the tick can transmit Lyme disease, too.

So while we don’t know for sure that they’d spread local diseases here, they appear (like many other ticks) to be capable of carrying a host of different pathogens. And as we’ve seen with the spread of ticks that carry Lyme disease, red meat allergy, and other illnesses, we have a hard time getting rid of ticks.

“[W]e advocate continued vigilance because even if this species is not already established in the United States, suitable hosts and habitats are common and widespread here,” the report’s authors wrote.

____________

For More:  https://madisonarealymesupportgroup.com/2018/03/01/asian-ticks-mysteriously-turn-up-in-new-jersey/

https://madisonarealymesupportgroup.com/2017/11/24/new-tick-discovered/

They’ve now found ticks bite each other potentially spreading pathogens to each other:  https://madisonarealymesupportgroup.com/2018/03/07/tick-bites-tick-hyperparasitism/

https://madisonarealymesupportgroup.com/2018/03/11/range-expansion-of-tick-disease-vectors-in-north-america-implications-for-spread-of-tick-borne-disease/

Forget Dracula.  We have ticks….

 

 

 

 

 

 

 

 

The Eleven Year Old Boy Who Knows More About Lyme/MSIDS Than Most Doctors

  Approx. 6.5 Min

Published on Mar 6, 2018

An introduction to Lyme Disease, Symptoms, Treatment, Prevention, and challenges from the perspective of an 11 year old who started his own advocacy group. The information has been vetted for accuracy by biologists and doctors working in Lyme research and treatment.
Removal of Tick using tweezers: https://www.youtube.com/watch?v=27Mcs… (University of Manitoba)
Please check out these Lyme Organizations and Friends:

LivLyme Foundation: http://livlymefoundation.org LymeHope: http://www.lymehope.ca International Lyme and Associated Disease Society: http://www.ilads.org G. Magnotta Foundation http://www.gmagnottafoundation.com Lyme Out Loud Kids: https://www.facebook.com/lymeoutloudk…

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**Comment**

I am so impressed.  Kudos to Daniel Stimers for speaking out for patients too weak to do so themselves!

Don’t you find it a bit sad when a kid knows more than most doctors regarding the most common vector borne disease in the U.S.?

Infected Dogs With TBI’s Spreading Infection Across Borders

http://www.cbc.ca/news/canada/new-brunswick/dog-diseases-enter-new-brunswick-1.4209193 By Joseph Tunney, CBC News 

‘Trojan horse’: Veterinarian sees tick-borne diseases entering N.B. under radar

Dogs brought across the border are infected with bacteria that’s not native to New Brunswick

Dogs coming into New Brunswick from the U.S. are carrying diseases that can infect humans through tick bites, just as Lyme disease does, says a veterinarian who heads the animal welfare committee of New Brunswick vets.

Anaplasmosis, babesiosis and Ehrlichia are not native to New Brunswick, but the province has the conditions needed to make it a breeding ground for the bacteria, said Mary-Ellen Themens, whose committee is part of the New Brunswick Veterinary Medical Association, the group that regulates the profession.

mary-ellen-themensMary-Ellen Themens, chair of the animal welfare committee for the New Brunswick Veterinary Medical Association, says diseases are entering the province under the radar. (Mary-Ellen Themens/submitted)

“Naturally, if we’re importing the disease, it’s going to accelerate the problem,” Themens said.

The three diseases are rampant in parts of the southern United States and Cuba, and now all three have been found on the East Coast in dogs that crossed the border, some brought in illegally and others infected without their owners’ knowledge, she said.

“I have a file in front of me of a dog imported in February 2017 from Cuba,” she wrote in an email. “It tested positive for Ehrlichia.”

Anaplasmosis is spread to humans through the same tick as Lyme disease. In humans, it can cause vague symptoms such as fever, muscle pain and chills.

“It can be a serious illness if not treated properly, and the fatality rate is less than one per cent, but not zero, in people,” Themens said.

Babesiosis, carried by the same blacklegged tick, destroys red blood cells, she said.

And Ehrlichia, which can cause serious illness, is transmitted to humans by a tick not normally found in New Brunswick.

Birds also bring in ticks

The tick recently landed in the province, however, apparently coming in on migratory birds.

“The fatality rate is estimated at 1.8 per cent,” Themens said of Ehrlichia.

Rabies is the only federal reportable disease in domestic dogs that is regulated at the border and in Canada, Rod Lister, media relations for Canadian Food Inspection Agency, wrote in an email.

“Either the province of New Brunswick or municipal governments may regulate the (other) diseases,” he said.

But the risks posed by these tick-borne diseases are not on most people’s radar, said Themens, meaning no additional laws regulating them exist.

What’s also worrying, she said, is that parts of the province can sustain the ticks and the illnesses through the winter.

“And, again, these are not diseases we are currently looking for,” she said. “These are things we don’t normally see.”

“They can be fatal.”

The public health department has not had any reports of people getting anaplasmosis or babesiosis, said spokesperson Paul Bradley.

Public health does tests

According to Dr. Jennifer Russell, acting chief medical officer of Health, blacklegged ticks in the province are tested for Lyme disease, human anaplasmosis and human babesiosis.

No human cases have been recorded in New Brunswick, but all of these diseases are reportable to public health and are being monitored.

“Further, dogs may develop lameness and other clinical signs if infected with (Lyme disease),” Russell said in a statement. “Blacklegged ticks can transmit the bacteria to dogs. Animal owners should consult with their veterinarian about the many tick prevention products that are available.”

In the case of Ehrlichia and unlike the other two illnesses, breeding populations of the lone star tick have not been identified in New Brunswick.

For now, Themens just hopes people start taking the idea of checking any incoming shelter dogs, either before or directly after entering the province, seriously.

Ideally, before it’s too late.

“It’s like a Trojan horse,” she said. “You’re bringing in the problem.”

_____________

**Comment**

Researchers and public authorities are not connecting the dots that add up to a very sick and infected population.  This article points out just two dots:  infected dogs coming across boarders and birds.  There’s lots of other vectors & reservoirs crossing boarders as well.

Cumulatively, this could all explain the high infection rates, along with the very real probability much of this can be a STD & spread congenitally:  https://madisonarealymesupportgroup.com/2018/02/06/lyme-in-the-southern-hemisphere-sexual-transmission/ and https://madisonarealymesupportgroup.com/2018/02/26/transplacental-transmission-fetal-damage-with-lyme-disease/

And then there’s the added issue that most patients are coinfected with numerous pathogens:  https://madisonarealymesupportgroup.com/2017/05/01/co-infection-of-ticks-the-rule-rather-than-the-exception/ and https://madisonarealymesupportgroup.com/2017/07/01/one-tick-bite-could-put-you-at-risk-for-at-least-6-different-diseases/

For more:  https://madisonarealymesupportgroup.com/2017/08/17/of-birds-and-ticks/

https://madisonarealymesupportgroup.com/2016/10/02/the-role-of-birds-in-tickborne-illness/

 

 

 

Bartonella Outbreak in Homeless

https://patch.com/washington/seattle/3-disease-outbreaks-king-county-put-homeless-risk

3 Disease Outbreaks In King County Put Homeless At RiskFile photo by Neal McNamara/Patch

 

SEATTLE, WA – King County Public Health investigators are looking into outbreaks of three diseases that are especially harmful for the local homeless population – and a fourth outbreak may be emerging.

According to Health Officer Dr. Jeff Duchin, health officials are seeing a big increase of group A streptococcus infections and shigella, which causes gastrointestinal distress. There’s also a cluster of trench fever cases, a painful illness spread through body lice carrying the bacteria Bartonella quintana. There have been three trench fever cases among the homeless since mid-2017, according to Duchin.

Additionally, Duchin said, the department is monitoring for a possible Hepatitis A outbreak – a type of hepatitis that infects the liver and can be spread through contact with infected feces.

These illnesses are particularly tough on the homeless because they lack access to proper medical care. Hepatitis A, for example, can be prevented by taking a vaccine.

“People who lack permanent housing often also have limited access to medical care, so many people living homeless and with health problems have difficulty getting prompt treatment. Living conditions – like crowding and fewer opportunities for personal hygiene – can contribute to the spread of disease,” Duchin said in a blog post.

King County is working with the state Department of Health, the Centers for Disease Control, and Harborview Medical Center to address the strep problem. The county is also spreading information about the other illnesses through homeless outreach.

________________

**Comment**

There is conflicting information regarding Bartonella transmission by ticks; however, prudence would err on the side of caution.  Nearly every patient I work with has Bartonella – and I think it is far more prevalent than many think.  Even the CDC states that ticks carry some species of Bart.  In my experience if the CDC acknowledges something, it is far worse in reality.  https://wwwnc.cdc.gov/eid/article/16/3/09-0443_article

Somehow, Lyme patients are getting Bartonella.

The problem lies in the fact researchers state that the presence of a pathogen in a tick does not imply they can transmit it – and therefore is not epidemiologically important.  They typically do “reviews” of previous studies to only conclude transmission has not been established.

Please know these studies are approximately 10 years old and older.  And again, garbage in, garbage out.  They keep recycling old studies and regurgitating ancient information.

If I had a dime for every time I read the words, “rare,” or “atypical” regarding Lyme/MSIDS, I’d be a rich woman.  Trust me, this stuff isn’t rare.  Just look around.

More on Bartonella: https://madisonarealymesupportgroup.com/2016/01/03/bartonella-treatment/  (Checklist found in link)

https://madisonarealymesupportgroup.com/2016/08/09/a-bartonella-story/

https://madisonarealymesupportgroup.com/2018/02/07/finally-rt-pcr-detected-bartonella-henselae-dna-on-tissue-valve/

https://madisonarealymesupportgroup.com/2018/03/04/bartonella-erythema-nodosum-atypical-presentations/

https://madisonarealymesupportgroup.com/2018/02/08/anemic-dog-found-to-have-bartonella-resolved-with-prolonged-antibiotics/

https://madisonarealymesupportgroup.com/2017/08/02/neurological-and-immunological-dysfunction-in-two-patients-with-bartonella-henselae-bacteremia/

https://madisonarealymesupportgroup.com/2017/05/11/bartonella-henselae-in-children-with-congenital-heart-disease/

https://madisonarealymesupportgroup.com/2017/01/04/endocarditis-consider-bartonella/

https://madisonarealymesupportgroup.com/2017/07/31/shedding-light-on-bartonella/

I could go on and on to infinity.  Bartonella is a REAL PROBLEM.  Time for researchers to wake up from their stupor and do some current meaningful research.