Archive for the ‘Transmission’ Category

CDC Website Updated Today: Possibility of Mother to Fetus Transmission Of Lyme Disease

https://www.lymehope.ca/news-and-updates/cdc-website-updated-today-possibility-of-mother-to-fetus-transmission-of-lyme?

CDC Website Updated Today: Possibility of Mother to Fetus Transmission of Lyme Disease

1/31/2020

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The CDC has updated their website today in three different spots to address the very important issue of maternal-fetal transmission of Lyme disease, from an infected mother to her fetus/baby.

The first update is in the Transmissionsection under ‘Are there other ways to get Lyme disease‘  which states:  ​

‘Untreated Lyme disease during pregnancy can lead to infection of the placenta. Spread from mother to fetus is possible but rare. Fortunately, with appropriate antibiotic treatment, there is no increased risk of adverse birth outcomes. There are no published studies assessing developmental outcomes of children whose mothers acquired Lyme disease during pregnancy.’
The second update is in the Lyme Disease FAQ under the question ‘I am pregnant and think I have Lyme disease, what should I do? which states:
‘If you are pregnant and suspect you have contracted Lyme disease, contact your physician immediately.  Untreated Lyme disease during pregnancy can lead to infection of the placenta. Spread from mother to fetus is possible but rare. Fortunately, with appropriate antibiotic treatment, there is no increased risk of adverse birth outcomes.* There are no published studies assessing developmental outcomes of children whose mothers acquired Lyme disease during pregnancy.’* Silver HM. Lyme disease during pregnancy . Infect Dis Clin North Am. 1997 Mar;11(1):93-7.
The third update is to the Pregnancy and Lyme Disease poster.

Clearly addressing the possibility of transmission from an infected mother to her baby is so important and we hope and trust this will open new doors for families who have expressed concern that their children were infected in-utero, so as to access medical treatment, support, follow-up and care.  This update also provides confirmation of the necessity for urgent, dedicated, scientific and medical research, in this area.

It is clear that the issue of maternal-fetal transmission of Lyme disease requires urgent research and a collective, multi-disciplinary, ‘all-hands on deck’ approach to address this alternate mode of transmission.

We are thankful for CDC leadership on this specific issue. Other countries around the world will take note.

It is time that ALL voices are heard, validated and acted upon. We can and must work together for the sake of our children and future generations.

It is also important to note that the HHS Tick-Borne disease working group subcommittee Clinical Aspects of Lyme Disease, recently issued a report which also included a section:
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And, please remember, this is only about Lyme disease.  Most patients are infected with numerous pathogens which the CDC refuses to recognize.  Transmission studies on these pathogens hasn’t been done because they aren’t even considering them.  The effects of being infected with multiple things isn’t even on their radar, let alone being considered as an issue with maternal transmission.
They continue to tell us over and over ad nauseam that all of this is rare.

 

 

 

Illinois – 1st Person-to-Person Novel Coronavirus Spread in U.S.

http://outbreaknewstoday.com/illinois-reports-1st-person-to-person-novel-coronavirus-spread-in-us-13212/

Illinois reports 1st person-to-person novel coronavirus spread in US

January 30, 2020

By NewsDesk  @infectiousdiseasenews

Centers for Disease Control and Prevention Director, Dr Robert Redfield announced today the first person-to-person novel coronavirus (2019-nCoV) in the United States.

Image/Dr. Fred Murphy & Sylvia Whitfield/CDC

The case, from Chicago, Illinois, is the husband of the first novel coronavirus case in the state. The patient did not travel to Wuhan, China. He is currently in stable condition.

This is the sixth confirmed case in the US.

The Illinois Department of Health reports aggressively investigating contacts.

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For more:  https://madisonarealymesupportgroup.com/2020/02/01/on-the-origins-of-the-2019-ncov-virus-wuhan-china-experimental-vaccine-type/

Excerpt:

THE AVAILABLE EVIDENCE MOST STRONGLY SUPPORTS THAT THE 2019-NCOV VIRUS IS A VACCINE STRAIN OF CORONAVIRUS EITHER ACCIDENTALLY RELEASED FROM A LABORATORY ACCIDENT, PERHAPS A LABORATORY RESEARCHER BECOMING INFECTED WITH THE VIRUS WHILE CONDUCTING ANIMAL EXPERIMENTS, OR THE CHINESE WERE PERFORMING CLINICAL STUDIES OF A CORONAVIRUS VACCINE IN HUMANS.

IF THE CHINESE GOVERNMENT HAS BEEN CONDUCTING HUMAN TRIALS AGAINST SARS, MERS, OR OTHER CORONAVIRUSES USING RECOMBINED VIRUSES, THEY MAY HAVE MADE THEIR CITIZENS FAR MORE SUSCEPTIBLE TO ACUTE RESPIRATORY DISTRESS SYNDROME UPON INFECTION WITH 2019-NCOV CORONAVIRUS.

The implications are clear: if China sensitized their population via a SARS vaccine, and this escaped from a lab, the rest of world has a serious humanitarian urgency to help China, but may not expect as serious an epidemic as might otherwise be expected.

In the worst-case scenario, if the vaccination strain is more highly contagious and lethal, 2019-nCoV could become the worst example of vaccine-derived contagious disease in human history.

 

 

 

 

 

Borrelia Crocidurae in Vaginal Swab After Miscarriage

https://www.ncbi.nlm.nih.gov/pubmed/31863877

2019 Dec 18. pii: S1201-9712(19)30493-X. doi: 10.1016/j.ijid.2019.12.020. [Epub ahead of print]

Detection of Borrelia crocidurae in a vaginal swab after miscarriage, rural Senegal, Western Africa.

Abstract

Tick-borne relapsing fever (TBRF) borrelias are one of the main causes of fever in rural Africa and can cause miscarriages. Here, we detected, for the first time to the best of our knowledge, Borrelia crocidurae in a self-vaginal sampling as a probable cause of spontaneous miscarriage.

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**Comment**

When will mainstream medicine wake up?  When will they connect the dots that borrelia is all over genitilia?  That there is a real probability it can be sexually and congenitally transmitted?  When will they quit saying that because something is “rare” it doesn’t happen?  If you are the sorry sucker who contracted it that way – are you unimportant?

Borrelia is defying all boxes people attempt to put it into.

According to this paper written in 2013, Borrelia crocidurae, associated with tick-borne relapsing fever, is stated as being benign in one breath and then extremely neurotropic and can cross the blood/brain barrier and persist, as well as cause encephalitis and meningitis, in the next breath.  None of which are benign in my book:  https://wwwnc.cdc.gov/eid/article/19/2/12-1325_article

And now it’s been found in a vaginal swab after a miscarriage.
This is a perfect example of how research for all things tick related is still in the Dark Ages.

Malaria Hides In People Without Symptoms

https://researchblog.duke.edu/2019/11/11/malaria-hides-in-people-without-symptoms/?

Malaria Hides In People Without Symptoms

It seems like the never-ending battle against Malaria just keeps getting tougher. In regions where Malaria is hyper-prevalent, anti-mosquito measures can only work so well due to the reservoir that has built up of infected humans who do not even know they carry the infection.

In high-transmission areas, asymptomatic malaria is more prevalent than symptomatic malaria. Twenty-four percent of the people in sub-Saharan Africa are estimated to harbor an asymptomatic infection, including 38 to 50 percent of the school-aged children in western Kenya. Out of the 219 million malaria cases in 2017 worldwide, over 90%  were in sub-Saharan Africa….(See link for full article)

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**Comment**

I post this because Malaria is a protozoan similar to Babesia.  The question begging to be asked is, “Can people also have an asymptomatic Babesia infection that lies around for an opportune time to emerge?”

My educated guess is yes, it can.

Key quote:  “P. falciparum malaria is very diverse in the region,” she said. “It’s constantly mutating, which is why it’s so hard to treat….many study participants were infected with multiple, genetically-distinct malaria infections. Some carried up to fourteen strains of the parasite.

For more:  https://madisonarealymesupportgroup.com/category/babesia-treatment/

https://madisonarealymesupportgroup.com/2018/10/11/babesia-found-in-patient-with-persistent-symptoms-following-lyme-treatment/

https://madisonarealymesupportgroup.com/2019/09/05/babesia-subverts-adaptive-immunity-and-enhances-lyme-disease-severity/

We show that

  • burgdorferi infection attenuates parasitemia in mice while
  • B. microti subverts the splenic immune response, such that a marked decrease in splenic B and T cells, reduction in antibody levels and diminished functional humoral immunity, as determined by spirochete opsonophagocytosis, are observed in co-infected mice compared to only B. burgdorferi infected mice

Furthermore

  • immunosuppression by B. microti in coinfected mice showed an association with enhanced Lyme disease manifestations.
Due to the high prevalence of infection and the issues of congenital transmission and transmission through blood transfusion, the issue of concurrent infection and what it does to animal and human health is of paramount importance.

Detection & Transstadial Passage of Babesia Species and Borrelia Burgdorferi Sensu Lato in Ticks Collected From Avian and Mammalian Hosts in Canada

Detection and Transstadial Passage of Babesia Species and Borrelia burgdorferi Sensu Lato in Ticks Collected from Avian and Mammalian Hosts in Canada 

John D. Scott 1,*, Kerry L. Clark 2, Nikki M. Coble 2 and Taylor R. Ballantyne 2 

Received: 24 October 2019; Accepted: 26 November 2019; Published: 2 December 2019 

Abstract: Lyme disease and human babesiosis are the most common tick-borne zoonoses in the Temperate Zone of North America. The number of infected patients has continued to rise globally, and these zoonoses pose a major healthcare threat. This tick-host-pathogen study was conducted to test for infectious microbes associated with Lyme disease and human babesiosis in Canada. Using the flagellin (flaB) gene, three members of the Borrelia burgdorferi sensu lato (Bbsl) complex were detected, namely a Borrelia lanei-like spirochete, Borrelia burgdorferi sensu stricto (Bbss), and a distinct strain that may represent a separate Bbsl genospecies. This novel Bbsl strain was detected in a mouse tick, Ixodes muris, collected from a House Wren, Troglodytes aedon, in Quebec during the southward fall migration. The presence of Bbsl in bird-feeding larvae of I. muris suggests reservoir competency in three passerines (i.e., Common Yellowthroat, House Wren, Magnolia Warbler). Based on the 18S ribosomal RNA (rRNA) gene, three Babesia species (i.e., Babesia divergens-like, Babesia microti, Babesia odocoilei) were detected in field-collected ticks. Not only was B. odocoilei found in songbird-derived ticks, this piroplasm was apparent in adult questing blacklegged ticks, Ixodes scapularis, in southern Canada. By allowing live, engorged ticks to molt, we confirm the transstadial passage of Bbsl in I. muris and B. odocoilei in I. scapularis. Bbss and Babesia microti were detected concurrently in a groundhog tick, Ixodes cookei, in Western Ontario. In Alberta, a winter tick, Dermacentor albipictus, which was collected from a moose, Alces alces, tested positive for Bbss. Notably, a B. divergens-like piroplasm was detected in a rabbit tick, Haemaphysalis leporispalustris, collected from an eastern cottontail in southern Manitoba; this Babesia species is a first-time discovery in Canada. This rabbit tick was also co-infected with Borrelia lanei-like spirochetes, which constitutes a first in Canada. Overall, five ticks were concurrently infected with Babesia and Bbsl pathogens and, after the molt, could potentially co-infect humans.

Notably, we provide the first authentic report of I. scapularis ticks co-infected with Bbsl and B. odocoilei in Canada.

The full extent of infectious microorganisms transmitted to humans by ticks is not fully elucidated, and clinicians need to be aware of the complexity of these tick-transmitted enzootic agents on human health. Diagnosis and treatment must be administered by those with accredited medical training in tick-borne zoonosis. 

Full article: Scott et al., 2019, Babesia spp. and Borrelia spp., Canada

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). 

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**Comment**

Transstadial passage is the ability of an infection to pass from one one developmental stage of an organism to another, e.g.,from the larval to the nymph stage or from the nymph to the adult:  https://medical-dictionary.thefreedictionary.com/transstadial

In this report the authors confirm the transstadial passage of Bbsl in I. muris and B. odocoilei in I. scapularis (black legged deer tick).

According to the following 2000 article, Ixodes muris is also capable of transmitting Lyme disease:  https://bioone.org/journals/Journal-of-Medical-Entomology/volume-37/issue-5/0022-2585-37.5.766/Vector-Competence-of-Ixodes-muris-Acari–Ixodidae-for-Borrelia/10.1603/0022-2585-37.5.766.short

Also, the following 2014 article states, “early studies revealed a higher ratio of presumed nonpathogenic B. odocolei to B. microti in areas where these species co-exist.”  https://wwwnc.cdc.gov/eid/article/20/10/13-0938_article

I think it would be folly to presume anything, and the potential of B. odocoilei to be of concern to human health is relevant. In my opinion, far too much as been presumed about the ability of various ticks to transmit disease, the time it takes to transmit, as well as the ability of numerous strains of pathogens to be of human health concern.

A few things are for sure: more and more is coming out on the coinfection of ticks, that there are many strains and variations of these pathogens to be concerned with, and that current testing is abysmal in picking much of this up.  These issues are some of the factors as to why people remain ill.  Mainstream medicine must awaken from its coma to embrace the complexity of all of this or patients will continue to suffer.