Archive for the ‘Sleep’ Category

Can Microdoses of Psychedelics Effectively Treat Neuro-Lyme?

https://www.lymedisease.org/microdosing-psychedelics-lyme/

Can microdoses of psychedelics effectively treat neuro-Lyme?

Dr. Dan Kinderlehrer

By Daniel A Kinderlehrer, MD

Those of us dealing with Lyme disease are well aware that most symptoms reside in the musculoskeletal and nervous systems. And for many of us, the worst symptoms in the nervous system are neuropsychiatric. The severity of anxiety, panic attacks, depression, irritability and rage can be overwhelming.

Chronic tick-borne infections can also cause bipolar disease, addiction syndromes, eating disorders, obsessive compulsive disorder and psychosis.1-8 And of course, it is all compounded by impaired sleep, brain fog, fatigue and chronic pain, not to mention physician ignorance.

Neuroinflammation

It turns out that these mental health symptoms are primarily caused by inflammation from infection outside the nervous system.9

For example, kids with PANS—Pediatric Acute-onset Neuropsychiatric Syndrome—have infections in which antibodies to different microbes cross the blood brain barrier and attack the brain, resulting in severe mood and behavioral disturbances.10 A similar process occurs in adults with neuropsychiatric Lyme disease.11-13

There is increasing recognition that many mood disorders are linked to infections and autoimmune disorders, and the common link is neuroinflammation—brain on fire.14

It is no surprise that people with neuropsychiatric Lyme disease have elevated levels of inflammatory mediators including antineuronal antibodies, cytokines, chemokines and inflammatory lipoproteins.9  Think of neuropsychiatric Lyme disease as autoimmune inflammation of the brain. The primary legs of treatment are antimicrobials, psychotropic medications and anti-inflammatory agents. Ideally, an anti-inflammatory agent will decrease inflammation but not suppress immune function.

In March 2023, I published a report describing a patient with long standing Lyme disease, Babesia and Bartonella infections in which the primary symptoms were neuropsychiatric.15 He experienced anxiety with panic attacks, depression with suicidal ideation and sleeplessness.

These symptoms gradually came under control with appropriate treatment, but a change in his regimen resulted in a severe relapse. He could no longer tolerate even low dose antimicrobials without Herxheimer reactions, Zoloft was not helping and he could not tolerate Ativan for anxiety. In fact, any benzodiazepine increased his suicidality. That is when his daughter suggested he try microdosing.

A new approach: psychedelic microdosing

This is from the case study that I published:

After a 40-year prohibition in the US of lysergic acid diethylamide (LSD) and psilocybin, there has been renewed interest in their potential for therapeutic benefit. The preponderance of research in the past two decades has been in controlled clinical settings in which subjects are administered a single high dose of a hallucinogen while under the supervision of a therapist/guide. In 2018 the US Food and Drug Administration categorized psilocybin as ‘a breakthrough therapy’ in the treatment of depression, a designation the agency applies to drugs that in early trials demonstrate substantial improvement over existing treatments.16

There is compelling evidence that psilocybin has potential value in the treatment of some mental health conditions. Multiple studies have documented its effectiveness in patients with depression, anxiety syndromes, end of life anxiety, and suggested benefit in OCD and addiction disorders.17-23

Microdosing is the practice of consuming very low, sub-hallucinogenic doses of a psychedelic substance on a regular basis. The intention of microdosing is to offer similar benefits to full dose psychedelic therapy, but without perceptual distortions, the need for clinical oversight, or the risk of a bad trip.” 24

Microdosing has become increasingly popular. In one online microdosing forum that was begun in 2013, the number of subscribers rose to 40,000 in 2018 and 219,000 in October 2022.25 LSD and psilocybin continue to be listed as schedule I controlled substances, meaning legally they have no accepted therapeutic value. Nevertheless, possession of psilocybin has been decriminalized in many US cities and is on the ballot of many states to be legalized in clinical therapeutic settings; Oregon and Colorado have already done so.26

No longer suicidal

The subject of my case history began microdosing three times weekly at doses one-fiftieth of a typical hallucinogenic journey. Within two days he was no longer suicidal and within two weeks he felt well. He continues to microdose and feels well three years later.

No wonder they call psilocybin magic mushrooms. It is a potent stimulator of serotonin and may also have some influence on dopamine.27 But what may be more crucial is its anti-inflammatory action. It significantly inhibits pro-inflammatory cytokines such as tumor necrosis factor-alpha, interleukins IL-1b, and IL-6, and cyclooxygenase-2 concentrations in human macrophage cells.28-30

It turns out that most mental health disorders are caused by neuroinflammation. That’s right: most patients with anxiety, depression, bipolar disorder and even psychosis have inflammation in their brains driving their mood disorders.31

Neuroinflammation in these patients may be caused by undiagnosed tick-borne infections, but there are multiple other drivers of inflammation. Autoimmune diseases such as lupus, Sjögrens syndrome, rheumatoid arthritis and multiple sclerosis are well documented causes of neuropsychiatric illness.32-37  Stress by itself can result in inflammatory conditions.38 People with childhood histories of adverse events such as physical or sexual abuse have an increased risk of autoimmune problems.39

Patients with PTSD—Post Traumatic Stress Disorder—don’t just have hypervigilance and anxiety disorders. They develop the same nervous, immune and endocrine system dysregulation as patients with persistent tick-borne infections and neuropsychiatric disease.40

The role of genetics

Meanwhile, genetics plays a significant role in the development of autoimmune conditions. Add to this epigenetic transmission that alters gene expression without changing the underlying DNA expression, and allows for trauma to be handed down from one generation to the next41—just ask children and grandchildren of Holocaust survivors.

Microdosing psilocybin holds the potential to help patients suffering from these mental health issues. Numerous studies suggest that microdosing is effective in the treatment of anxiety and depression.42-46 Unfortunately, these studies are not controlled and are reliant on subject reporting—it is impossible to separate benefits from placebo effect. We clearly need better research on microdosing.

Presently Johns Hopkins University is recruiting for a study in which patients with PTLDS—Post Treatment Lyme Disease Syndrome—are treated with full hallucinogenic doses of psilocybin under the supervision of a therapist/guide.47 These ‘journeys’ last four or more hours in controlled settings. I hope this research finds positive benefits of treatment, but full dose psilocybin treatment demands excessive resources that will never be available to most patients with Lyme.

Those of us with “Chronic Lyme” know that PTLDS is actually persistent infection with Borrelia burgdorferi complicated by the existence of co-infections resulting in systemic inflammation—it is an autoimmune illness.48 In a review of the physiological effects of psychedelics, the authors Caitlin Thompson and Attila Szabo “…propose that psychedelics hold the potential to attenuate or even resolve autoimmunity.”

The bottom line is that microdosed psilocybin may be an important adjunct to the treatment of mental illness. It is time that we find the resources to perform properly controlled double-blind investigations into the impact of microdosed psilocybin on patients with neuropsychiatric Lyme disease as well as those suffering from the ever-increasing numbers suffering from mental health disorders.

Click here to read the entire case report.

Dr. Daniel Kinderlehrer is an internal medicine physician in Denver, Colorado, with a practice devoted to treating patients with tick-borne illness. He is the author of  Recovery From Lyme Disease: The Integrative Medicine Guide to the Diagnosis and Treatment of Tick-Borne Illness.

References
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  2. Bransfield RC. Lyme Disease, comorbid tick-borne diseases, and neuropsychiatric disorders. Psychiatr Times. 2007 Dec 1;24(14):59–61.
  3. Fallon BA, Nields JA, Burrascano JJ, et al. The neuropsychiatric manifestations of Lyme borreliosis. Psychiatr Q. 1992;63(1):95–117.
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  6. Bransfield RC. Aggressiveness, violence, homicidality, homicide, and Lyme disease. Neuropsychiatr Dis Treat. 2018 Mar 9;14:693-713. doi: 10.2147/NDT.S155143. PMID: 29576731; PMCID: PMC5851570.
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  11. Coughlin JM, Yang T, Rebman AW, et al. Imaging glial activation in patients with post-treatment Lyme disease symptoms: a pilot study using [11C]DPA-713 PET. J Neuroinflammation. 2018 Dec 19;15(1):346.
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  13. Fallon BA, Stobino B, Reim S, Stoner J, Cunningham MW. Anti-lysoganglioside and other anti-neuronal antibodies in post-treatment Lyme disease and erythema migrans after repeat infection. Brain Behav Immun. 2020;2:100015.
  14. Benros ME, Waltoft BL, Nordentoft M, et al. Autoimmune Diseases and Severe Infections as Risk Factors for Mood Disorders: A Nationwide Study. JAMA Psychiatry.2013;70(8):812–820. doi:10.1001/jamapsychiatry.2013.1111.
  15. Kinderlehrer DA. The Effectiveness of Microdosed Psilocybin in the Treatment of Neuropsychiatric Lyme Disease: A Case Study. Int Med Case Rep J. 2023 Mar 3;16:109-115. doi: 10.2147/IMCRJ.S395342. PMID: 36896410; PMCID: PMC9990519.
  16. approval-priority-review/breakthrough-therapy (Accessed October 10, 2022)
  17. Davis AK, Barrett FS, May DG, et al. Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2021 May 1;78(5):481-489. doi: 10.1001/jamapsychiatry.2020.3285. Erratum in: JAMA Psychiatry. 2021 Feb 10;: PMID: 33146667; PMCID: PMC7643046.
  18. Moreno FA, Wiegand CB, Taitano EK, Delgado PL. Safety, tolerability, and efficacy of psilocybin in 9 patients with obsessive-compulsive disorder. J Clin Psychiatry. 2006 Nov;67(11):1735-40. doi: 10.4088/jcp.v67n1110. PMID: 17196053.
  19. Khan AJ, Bradley E, O’Donovan A, Woolley J. Psilocybin for Trauma-Related Disorders. Curr Top Behav Neurosci. 2022;56:319-332. doi: 10.1007/7854_2022_366. PMID: 35711024.
  20. Bogadi M, Kaštelan S. A potential effect of psilocybin on anxiety in neurotic personality structures in adolescents. Croat Med J. 2021 Oct 31;62(5):528-530. doi: 10.3325/cmj.2021.62.528. PMID: 34730895; PMCID: PMC8596485.
  21. Yu CL, Yang FC, Yang SN, et al. Psilocybin for End-of-Life Anxiety Symptoms: A Systematic Review and Meta-Analysis. Psychiatry Investig. 2021 Oct;18(10):958-967. doi: 10.30773/pi.2021.0209. Epub 2021 Oct 8. PMID: 34619818; PMCID: PMC8542741.
  22. Griffiths RR, Johnson MW, Carducci MA, et al. Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial. J Psychopharmacol. 2016 Dec;30(12):1181-1197. doi: 10.1177/0269881116675513. PMID: 27909165; PMCID: PMC5367557.
  23. Johnson MW, Garcia-Romeu A, Cosimano MP, Griffiths RR. Pilot study of the 5-HT2AR agonist psilocybin in the treatment of tobacco addiction. J Psychopharmacol. 2014;28(11):983-992. doi:1177/0269881114548296.
  24. Hutten NRPW, Mason NL, Dolder PC, Kuypers KPC. Motives and Side-Effects of Microdosing With Psychedelics Among Users. Int J Neuropsychopharmacol. 2019 Jul 1;22(7):426-434. doi: 10.1093/ijnp/pyz029. PMID: 31152167; PMCID: PMC6600464.
  25. https://www.reddit.com/r/microdosing/ (Accessed October 10, 2022)
  26. https://www.pewtrusts.org/en/research-and-analysis/blogs/stateline/2022/07/15/more-states-may-legalize-psychedelic-mushrooms (Accessed October 10, 2022)
  27. Coppola M, Bevione F, Mondola R. Psilocybin for Treating Psychiatric Disorders: A Psychonaut Legend or a Promising Therapeutic Perspective? J Xenobiot. 2022 Feb 7;12(1):41-52. doi: 10.3390/jox12010004. PMID: 35225956; PMCID: PMC8883979.
  28. Nkadimeng SM, Steinmann CML, Eloff JN. Anti-Inflammatory Effects of Four Psilocybin-Containing Magic Mushroom Water Extracts in vitro on 15-Lipoxygenase Activity and on Lipopolysaccharide-Induced Cyclooxygenase-2 and Inflammatory Cytokines in Human U937 Macrophage Cells. J Inflamm Res. 2021 Aug 5;14:3729-3738. doi: 10.2147/JIR.S317182. PMID: 34385833; PMCID: PMC8352634.
  29. Kubera M, Maes M, Kenis G, et al. Effects of serotonin and serotonergic agonists and antagonists on the production of tumor necrosis factor alpha and interleukin-6. Psychiatry Res. 2005 Apr 30;134(3):251-8. doi: 10.1016/j.psychres.2004.01.014. PMID: 15892984.
  30. Flanagan TW, Nichols CD. Psychedelics as anti-inflammatory agents. Int Rev Psychiatry. 2018 Aug;30(4):363-375. doi: 10.1080/09540261.2018.1481827. Epub 2018 Aug 13. PMID: 30102081.
  31. Yuan, N., Chen, Y., Xia, Y. et al.Inflammation-related biomarkers in major psychiatric disorders: a cross-disorder assessment of reproducibility and specificity in 43 meta-analyses. Transl Psychiatry9, 233 (2019). https://doi.org/10.1038/s41398-019-0570-y
  32. Shen CC, Yang AC, Kuo BI, Tsai SJ. Risk of Psychiatric Disorders Following Primary Sjögren Syndrome: A Nationwide Population-based Retrospective Cohort Study. J Rheumatol. 2015 Jul;42(7):1203-8. doi: 10.3899/jrheum.141361. Epub 2015 May 15. PMID: 25979721.
  33. Meszaros ZS, Perl A, Faraone SV. Psychiatric symptoms in systemic lupus erythematosus: a systematic review. J Clin Psychiatry. 2012 Jul;73(7):993-1001. doi: 10.4088/JCP.11r07425. Epub 2012 May 1. PMID: 22687742; PMCID: PMC9903299.
  34. Mura G, Bhat KM, Pisano A, Licci G, Carta M. Psychiatric symptoms and quality of life in systemic sclerosis. Clin Pract Epidemiol Ment Health. 2012;8:30-5. doi: 10.2174/1745017901208010030. Epub 2012 Apr 20. PMID: 22550545; PMCID: PMC3339425.
  35. Bernstein CN, Hitchon CA, Walld R, Bolton JM, Sareen J, Walker JR, Graff LA, Patten SB, Singer A, Lix LM, El-Gabalawy R, Katz A, Fisk JD, Marrie RA; CIHR Team in Defining the Burden and Managing the Effects of Psychiatric Comorbidity in Chronic Immunoinflammatory Disease. Increased Burden of Psychiatric Disorders in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2019 Jan 10;25(2):360-368. doi: 10.1093/ibd/izy235. PMID: 29986021; PMCID: PMC6391845.
  36. Lwin MN, Serhal L, Holroyd C, Edwards CJ. Rheumatoid Arthritis: The Impact of Mental Health on Disease: A Narrative Review. Rheumatol Ther. 2020 Sep;7(3):457-471. doi: 10.1007/s40744-020-00217-4. Epub 2020 Jun 13. PMID: 32535834; PMCID: PMC7410879.
  37. Silveira C, Guedes R, Maia D, Curral R, Coelho R. Neuropsychiatric Symptoms of Multiple Sclerosis: State of the Art. Psychiatry Investig. 2019 Dec;16(12):877-888. doi: 10.30773/pi.2019.0106. Epub 2019 Dec 9. PMID: 31805761; PMCID: PMC6933139.
  38. Calcia MA, Bonsall DR, Bloomfield PS, Selvaraj S, Barichello T, Howes OD. Stress and neuroinflammation: a systematic review of the effects of stress on microglia and the implications for mental illness. Psychopharmacology (Berl). 2016 May;233(9):1637-50. doi: 10.1007/s00213-016-4218-9. Epub 2016 Feb 5. PMID: 26847047; PMCID: PMC4828495.
  39. Dube SR, Fairweather D, Pearson WS, Felitti VJ, Anda RF, Croft JB. Cumulative childhood stress and autoimmune diseases in adults. Psychosom Med. 2009 Feb;71(2):243-50. doi: 10.1097/PSY.0b013e3181907888. Epub 2009 Feb 2. PMID: 19188532; PMCID: PMC3318917.
  40. Bransfield RC. Adverse Childhood Events, Post-Traumatic Stress Disorder, Infectious Encephalopathies and Immune-Mediated Disease. Healthcare (Basel). 2022 Jun 17;10(6):1127. doi: 10.3390/healthcare10061127. PMID: 35742178; PMCID: PMC9222834.
  41. Yehuda R, Lehrner A. Intergenerational transmission of trauma effects: putative role of epigenetic mechanisms. World Psychiatry. 2018 Oct;17(3):243-257. doi: 10.1002/wps.20568. PMID: 30192087; PMCID: PMC6127768.
  42. Rootman JM, Kryskow P, Harvey K, et al. Adults who microdose psychedelics report health related motivations and lower levels of anxiety and depression compared to non-microdosers. Sci Rep. 2021 Nov 18;11(1):22479. doi: 10.1038/s41598-021-01811-4. PMID: 34795334; PMCID: PMC8602275.
  43. Lea T, Amada N, Jungaberle, H. Psychedelic microdosing: A subreddit analysis. Psychoactive Drugs. 2020;52:101-112. https://doi.org/10.1080/ 02791072.2019.1683260.
  44. Lea T, Amada N, Jungaberle H, et al. Perceived outcomes of psychedelic microdosing as self-managed therapies for mental and substance use disorders. Psychopharmacology. 2020;237:1521. https://doi.org/10.1007/s00213-020-05477-0.
  45. FadimanThe psychedelic explorer’s guide: Safe, therapeutic, and sacred journeys.  Simon and Schuster, New York, 2021.
  46. Johnstad PG. Powerful substances in tiny amounts: an interview study of psychedelic microdosing. Nordic Stud Alcohol Drugs. 2018; 35(1):39–51. https://doi.org/10.1177/1455072517753339
  47. https://classic.clinicaltrials.gov/ct2/show/NCT05305105 (Accessed June 30, 2023)
  48. Yehudina Y, Trypilka S. Lyme Borreliosis as a Trigger for Autoimmune Disease. Cureus. 2021 Oct 10;13(10):e18648. doi: 10.7759/cureus.18648. PMID: 34786243; PMCID: PMC8578812.
  49. Thompson C, Szabo A. Psychedelics as a novel approach to treating autoimmune conditions. Immunol Lett. 2020 Dec;228:45-54. doi: 10.1016/j.imlet.2020.10.001. Epub 2020 Oct 7. PMID: 33035575.

Category:

Inflammation, Lyme, Psychological Aspects, research, Sleep, Treatment

LDN For Lyme

https://www.treatlyme.net/guide/low-dose-naltexone-lyme-disease

Updated: 3/21/23

About Low-Dose Naltrexone for Lyme

Low-dose naltrexone (LDN) is very useful in Lyme disease. This low-cost medicine can

  • improve nerve, muscle, and inflammation pain,
  • decrease autoimmune illness triggered by Lyme,
  • improve mast cell activation symptoms,
  • lower cytokine inflammation, and
  • improve immune system function by increasing TRegs to balance Th1 and Th2.

In this article, I review the science and method for how LDN works. I describe how to use it in Lyme disease, and I review potential side effects.  (See link for article & video)

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For more:

Category:

Inflammation, Lyme, Pain Management, Sleep, Supplements, Treatment

Cancers Increasing Dramatically & Did the COVID Shot Worsen A Famous Doctor’s Cancer?

**UPDATE Oct. 2022**

An analysis of U.S. Morbidity and Mortality Weekly Report (MMWR) data suggests the CDC has been filtering and re-designating cancer deaths as COVID deaths since April, 2021 to eliminate the cancer signal. The signal is being hidden by swapping the underlying cause of death with the main cause of death.  And before it was manipulated, data from the Defense Medical Epidemiology Database (DMED) showed cancer rates in military personal and in their families TRIPLED after the shot rollout. Cancer patients have also gotten younger with the largest increase among 30-50 year olds, with dramatically larger, and multiple tumors, occurring in multiple organs as well as recurrence and metastasis increasing.

https://www.sciencealert.com/cancers-in-adults-under-50-have-increased-dramatically-around-the-globe

Cancers in Adults Under 50 Have Increased Dramatically Around The Globe

By Fiona MacDonald, 08 September 2022

(bymuratdeniz/Getty Images)

Cancer has long been part of the human story. But a new review has shown that, recently, something has shifted.

Since 1990, the number of adults under the age of 50 developing cancer has increased dramatically around the world.

What’s concerning is that the increase in early-onset cancers doesn’t seem to be slowing down – and improvements in screening alone don’t seem to be able to fully explain the trend.

“We found that this risk is increasing with each generation,” says one of the researchers, Shuji Ogino, a pathologist and epidemiologist at Brigham and Women’s Hospital in Boston.

(See link for article)

__________________

SUMMARY:

  • The researchers looked at 14 cancer types:  breast, colorectal (CRC), endometrial, esophageal, extrahepatic bile duct, gallbladder, head and neck, kidney, liver, bone marrow, pancreas, prostate, stomach, and thyroid cancer – all of which are on the rise according to global cancer data.
  • Then they reviewed any available studies that could shed light on possible risk factors for these cancers by looking for clues in the literature describing any unique clinical and biological characteristics of tumors of early-onset cancers.
  • They found that early-onset cancer is an emerging global epidemic.
  • They found the following issues contributed to the uptick:
    • increased screening, however even countries that don’t have screening programs have increased cancer rates.
    • Diet
    • lifestyle
    • weight (obesity)
    • environmental exposures
    • microbiome
    • sedentary lifestyle
    • alcohol consumption
    • type 2 diabetes
  • Among the types of cancers studied 14 are related to the digestive system.
  • Regarding children, they are getting a lot less sleep than in the past.

The research has been published in Nature Reviews Clinical Oncology.

While the article doesn’t mention it specifically, radiation from wireless devices such as cell phones which have become prominent today may be adding to this cancer surge as well.  It is commonly known that EMFs wreak havoc in the body and many Lyme/MSIDS are particularly vulnerable.

Another little discussed topic is glyphosate, the major ingredient in Bayer-Monsanto’s Roundup which is the most widely used pesticide in the U.S. WHO and CA scientists both agree it is linked to cancer, yet the EPA concluded it was “safe” and “not likely” to cause cancer. The EPA has been forced to review this due to a federal judge finding the agency ignored human health studies, expert advice, and the agency’s guidelines for determining cancer risk. Source

And a 2021 study links lung cancer with mask usage.

Similarly to research regarding tick-borne illnesses, Alzheimer’s and cancer research have been controlled by a Cabal and researchers are currently accused of doctoring images, plagiarism, and faking data.

The article also doesn’t mention the link between the COVID mRNA shots and cancer:

  • the lipid nanoparticle mRNA COVID injection goes systemically into the entire body and doesn’t remain in the arm as thought.
  • It continues to produce the spike protein at least 60 days out if not longer and is being found 15 months later.
  • It also interferes with cancer blocking genes and they are seeing an uptick in cancers as well as other viruses now after the shots
  • there’s been a 40% increase in deaths those ages 18-64 years of age and an 84% increase in the 25-44 age group according to insurance companies.

The following story is a perfect example of the very real potential link:

https://thehighwire.com/videos/renowned-physician-documents-aggressive-cancer-post-covid-vaccines/  Video Here (Approx. 14 Min)

RENOWNED PHYSICIAN DOCUMENTS AGGRESSIVE CANCER POST COVID VACCINES

Belgian immunologist and medical research icon, Michel Goldman, had his values challenged when a Covid booster shot appeared to rapidly accelerate his cancer. He decided to go public with his story and tell the world.

https://www.theatlantic.com/science/archive/2022/09/mrna-covid-vaccine-booster-lymphoma-cancer/671308/

Did a Famous Doctor’s COVID Shot Make His Cancer Worse?

A lifelong promoter of vaccines suspects he might be the rare, unfortunate exception.
By Roxanne Khamsi
 
Sept. 24, 2022
 
Excerpts:
 
On September 22 of last year, Michel Goldman, a Belgian immunologist and one of Europe’s best-known champions of medical research, walked into a clinic near his house, rolled up his sleeve, and had a booster shot delivered to his arm.
 
Just a few weeks earlier, Michel, 67, had been to see his younger brother, Serge, the head of nuclear medicine at the hospital of the Université Libre de Bruxelles, where both men are professors. Michel was having night sweats, and he could feel swollen lymph nodes in his neck, so his brother brought him in for a full-body CT scan. When the images came through to Serge’s computer they revealed a smattering of inky spots, bunched near Michel’s left armpit and running up along his neck. It was cancer of the immune system—lymphoma.
 

Given his own area of expertise, Michel understood this meant he’d soon be immunocompromised by chemotherapy. With another winter on the way—and perhaps another wave of SARS-CoV-2 infections—that meant he had just a narrow window of opportunity in which his body would respond in full to COVID vaccination. Having received two doses of Pfizer the prior spring, Michel quickly went to get his third. If he was about to spend months absorbing poison as he tried to beat a deadly cancer, at least he’d have the most protection possible from the pandemic.

Within a few days, though, Michel was somehow feeling even worse. His night sweats got much more intense, and he found himself—quite out of character—taking afternoon naps. Most worryingly, his lymph nodes were even more swollen than before. He conferred with Serge again, and they set up another body scan for September 30, six days before Michel was scheduled to start his cancer treatment. Once again he sat in the radiology waiting room while his brother waited for the pictures to appear on his computer.

Serge’s bushy eyebrows furrowed when he spoke with Michel after having seen the scans. (“I will always remember his face, it was just incredible,” Michel told me.) The pictures showed a brand-new barrage of cancer lesions—so many spots that it looked like someone had set off fireworks inside Michel’s body. More than that, the lesions were now prominent on both sides of the body, with new clusters blooming in Michel’s right armpit in particular, and along the right side of his neck.  (See link for article)

___________________

SUMMARY:

  • It is unusual to see such a swift progression in just 3 weeks
  • He hand his brother had a gnawing feeling the booster made him sicker
  • The article erroneously states this is a very rare life-threatening side effect.  Doctors have been reporting this finding all over the world but are ignored.
  • An avid proponent of the shots, going to far as to reassure others about their safety, he’s definitely having a red pill experience.
  • Unfortunately he bought and propagated the lie that any chance of serious complications from the shots pale in comparison to the chance of complications from COVID.
  • Michael threw him into researching the mechanisms of action of the COVID shots and did find clues suggesting the the mRNA shots might be risky for a subset of the population as they are effective at generating a message and spurring its passage through helper T cells, which could give such a jolt to helper T cells that they go berserk.  Overstimulation on those prone to forming tumors in those already with cancer, overstimulation could make it worse.
  • He learned that body scans of some of those who get vaccines, including cancer patients, have shown heightened activity in the lymph nodes near the armpit on the side where the shot was received.
  • A mouse study also corroborated his experience.
  • Michael wrote a paper, about his experience titled “Rapid Progression of Angioimmunoblastic T Cell Lymphoma Following BNT162b2 mRNA Vaccine Booster Shot”
  • Worried his study would fuel vaccine skepticism he labored over every word, yet his paper follows earlier reports also suggesting a possible link between the COVID shot and lymphoma
  • Another doctor also worried that writing about five patients who had a relapse of kidney disease and eight patients who were newly diagnosed after getting the shot would also fuel vaccine skepticism.
  • Michael’s immunologist stated that the vaccine appeared to be related to the cancer’s behavior and then reneged by stating it’s just a case report – one patient.

Category:

Activism, diet and nutrition, Gut Health, research, Sleep

7 Conditions Masquerading As Dementia

https://greenmedinfo.com/blog/7-conditions-masquerading-dementia

7 Conditions Masquerading As Dementia

Monday, May 30th 2022
Written By:GMI Reporter

7 Conditions Masquerading As Dementia

More than 40% of dementia diagnoses have been shown to be wrong.  Here’s what may really be going on.  

Imagine this nightmare. For the last few years your mother has had serious memory problems.  She gets lost driving.  She repeats the same question to you over and over again.  She can’t process new information.  She loses her train of thought in mid-sentence.  A CT scan comes back with a diagnosis of early Alzheimer’s disease.  The doctors offer a prescription with little encouragement it will work.

Do you despair?

A new program from UCLA and the Buck Institute for Research on Aging offers new hope.  In the first study of its kind, researchers have proved that natural therapies can not only slow the progress of dementia but can actually reverse it.

In a paper titled “Reversal of Cognitive Decline: A novel therapeutic program” Dr. Dale Bredesen showed how 9 out of the 10 subjects diagnosed with dementia got their minds back.[i]

(See link for article)

______________________

SUMMARY:

  • Study results were remarkable with 9 of the 10 showing improvement in memory within three to six months.
  • Treatment was a “systems approach” which included dietary changes, exercise, brain stimulation, sleep optimization, pharmaceuticals and vitamins, etc.  Specifically:
    • eliminating all simple carbohydrates;
    • eliminating gluten and processed food;
    • increasing vegetables, fruits, and non-farmed fish;
    • reducing stress with yoga and meditation;
    • taking melatonin each night;
    • increasing sleep from 4-5 hours per night to 7-8 hours per night;
    • taking methylcobalamin (vitamin B12), vitamin D, CoQ10, and fish oil each day;
    • optimizing oral hygiene using an electric flosser and electric toothbrush;
    • hormone replacement therapy;
    • fasting for a minimum of 12 hours between dinner and breakfast;
    • fasting for a minimum of three hours between dinner and bedtime;
    • exercising for a minimum of 30 minutes, 4-6 days per week.
  • The only side effect was improved health and weight
  • (www.sharpagain.org) educates the public and the medical community about the reversible causes of dementia.
They give 7 areas to investigate before accepting a dementia or Alzheimer’s diagnosis.
  1. Nutritional imbalances and deficiencies. Deficiencies of omega 3s, vitamin B12, vitamin C, magnesium, selenium, probiotics, and other nutrients frequently cause symptoms of Alzheimer’s and dementia.
  2. Artificial food colors, flavors, and sweeteners. Artificial additives of all kinds may cause dementia symptoms.
  3. Prescription medication side effects. Drugs, especially pain medications, and psychotropic drugs can severely disrupt cognition.
  4. Inflammation from low-level infections, mold, food allergies, and Lyme Disease. Inflammation is the body’s attempt to get rid of a toxic element or organism, and so it occurs in many different situations, even root canals and urinary tract infections.
  5. Stress and stagnation/inactivity. Stress elevates cortisol levels, leading to inflammation, and in turn to hormone imbalances, cognitive impairment, heightened blood sugar levels, hypertension, delayed healing time, and susceptibility to disease.
  6. Thyroid and other hormonal imbalances. Many people diagnosed with Alzheimer’s or dementia simply have low levels of T3 thyroid hormone. However, standard thyroid tests completely miss T3 levels, and Synthroid (T4) doesn’t help. It is estimated that 10 to 15% of all nursing home residents may be there because of low T3.
  7. Mercury and other heavy metal poisoning. So-called silver amalgam fillings contain 50 percent mercury, and that mercury is neither stable nor inert. It off-gasses, crosses the blood-brain barrier, and destroys neurons even without contact. Removing these fillings is hazardous unless done with mercury-safe protocols.  Annual flu shots are another source of these toxins.

Since doctors are not experts in dementia causes or how to treat it, Sharp Again Naturally is building a medical advisory board and a database. It also offers help finding functional medicine specialists, naturopaths, or doctors who practice integrative medicine who are familiar with these areas.

Click here for more information on natural approaches to preventing and overcoming dementia.

Additional References

[i] Dale E. Bredesen, “Reversal of Cognitive decline: A novel therapeutic program.” AGING, September 2014, Vol. 6, No. 9.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of GreenMedInfo or its staff.
© [5/30/22] GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC. Want to learn more from GreenMedInfo? Sign up for the newsletter here //www.greenmedinfo.com/greenmed/newsletter.

Category:

Alzheimer's, diet and nutrition, Lyme, Mold, research, Sleep, Supplements, Treatment, vaccines

Bartonella Infection in Mom and Both Sons: Anxiety, Panic Attacks, Insomnia, Inconsolable Crying, Irritability, ADHD, Rage, and of Course Pain

https://www.everywomanover29.com/blog/bartonella-infection-in-mom-and-both-sons-anxiety-panic-attacks-insomnia-inconsolable-crying-irritability-adhd-rage-and-pain/

Bartonella infection in mom and both sons: anxiety, panic attacks, insomnia, inconsolable crying, irritability, ADHD, rage and pain

By

bartonella infection

A mom and both her sons experienced a variety of emotional/mood and pain symptoms between them as a result of a Bartonella infection: anxiety, panic attacks, insomnia, irritability, inconsolable crying, ADHD, rage, eye pain, joint pain and pain in the legs. This family case study was published in Parasites and Vectors in 2013. I would love to see individual amino acids being used to ease some of these symptoms while the infection is being treated (more on this below).

Here are some of the emotional and mood-related symptoms they experienced:

  • the mother and both sons developed recurrent rash-like skin lesions, disruptive sleep patterns and both boys developed anxiety accompanied by episodes of inconsolable crying, irritability, and panic attacks
  • subsequent to the spider infestation of the apartment, [the mother] developed fatigue, memory difficulties, headaches, irritability, eye pain, insomnia, chest pain, blurred vision, shortness of breath, rash and skin lesions and anxiety attacks.
  • The youngest son… awakened at night crying and complaining of pain in his legs
  • The older son experienced increased irritability and rage episodes. In addition, the boy’s teacher indicated a lack of attention during class, and suggested that the child might have an Attention Deficit Hyperactivity Disorder (ADHD).

The youngest son also developed severe neurological symptoms and was diagnosed with Guillain-Barre syndrome and Chronic Inflammatory Demyelinating Polyradiculoneuropathy.

You can read the full investigation, timing, sequence of events and all the symptoms in the paper: Bartonella henselae infection in a family experiencing neurological and neurocognitive abnormalities after woodlouse hunter spider bites  (For more see link)

___________________

**Comment**

Fantastic article that needs to be shared widely.  I believe Bartonella is much more common than doctors believe, and as in these cases, quite severe and debilitating.

A few points:

  • Please note the spider infestation. See this article for more on transmission.
  • The author mentions Chinese herbs, which in my experience aren’t strong enough to fight this alone.  This is just my experience, and my husband’s and numerous other patients, but and I realize perhaps there are others with a different experience than ours.
  • For us, when we relapse, it’s clearly Bartonella that immediately responds to the combination of rifampin and clarithromycin.  Within 2-3 months of treatment we push the symptoms away.
  • The author also gets into amino acids to address symptoms – of which I have little experience.  When in the midst of the battle, I hear Dr. Hoffman telling me that if I address the infection(s), the symptoms will either disappear entirely or lessen considerably.  I have proven this dictum repeatedly with each successive, treated relapse.  When money is an issue, you must decide the best course of action as many things are needed to successfully fight MSIDS.  As with everything else; however, each case is individual and for those suffering with severe psychiatric, sleep, and other issues, learning about amino acids may be a key part of treatment.
  • My husband has definitely found relief with 5-HTP & Gabapentin for sleep issues.  Strong CBD and melatonin has helped as well as LDN.  Lyme/MSIDS related insomnia is very real.

Please read the article in its entirety, but here’s a highlight on the various amino acids:

Category:

Bartonella, Psychological Aspects, Sleep, Transmission