Archive for the ‘research’ Category

Pfizer Reboots Lyme Vaccine Linked to Lyme-Disease-Like Autoimmune Arthritis and Class Action Lawsuits

This needs to be a hard pass for everyone on planet earth …..

https://jonfleetwood.substack.com/p/pfizer-reboots-lyme-vaccine-linked?

Pfizer Reboots Lyme Vaccine Linked to Lyme-Disease-Like Autoimmune Arthritis and Class Action Lawsuits

Forces your body to flood bloodstream with antibody proteins that ticks consume during feeding.
Jon Fleetwood
Apr 20, 2026

Pfizer and Valneva have advanced their experimental Lyme disease vaccine, PF-07307405 (LB6V, formerly VLA15), using the same core biological mechanism that sparked autoimmune arthritis concerns, lawsuits, and the eventual withdrawal of the only previous Lyme vaccine, LYMErix.

The jab works by forcing the body to produce antibodies against a bacterial protein that resembles a protein found in your own joint tissue, meaning those antibodies may also recognize similar structures in your joints and trigger an immune response there.

That means a mechanism previously tied to immune responses against joint tissue—producing Lyme-like symptoms—is now being brought back and positioned for broad public rollout.

Moreover, current data tracks antibody levels in the bloodstream over months, but does not map where those antibodies distribute in human tissues or how repeated boosting affects immune activity over the long term.  (See link for article)

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**Comment**

Great article.  Really.  I wish I could have said it better.

If the above information doesn’t scare you enough – catch this: the vaccine forces the body to produce large quantities of anti-OspA IgG that remain inactive UNTIL a tick bites you, then the activity takes place INSIDE the tick.  Come again? 

To further the horror, the SAME molecular OspA mimicry in LYMRrix is in in the Pfizer Lyme vaccine, only this new vaccine expands the design across SIX borrelia serotypes.  Translation: even more than the estimated 30% of vaccinated people could get treatment resistant arthritis as a result of covering more serotypes of Bb AND due to the necessary boosters.

And to pound the nail in the coffin for good, reported adverse events were declared to be unrelated to the vaccine by investigators who all worked for Pfizer!  

Fleetwood does all of us a favor by critically looking at the study and exposing the fact there isn’t data showing tissue distribution and long term effects, especially after repeated exposure – the SAME exact blind spots LYMErix had…..

History repeats itself……yet again.

Category:

Activism, Lyme, research, Ticks, vaccines

Pfizer’s Tick ‘Vaccine’ Exposed

https://x.com/Maninamerica/status/2044051346907611250

Pfizer’s Tick Vaccine EXPOSED, Iran War Escalates & Trump’s Greatest Reset

By Man in America

April 14, 2026

It’s tick season again.

Time magazine says so. Climate scientists say so. And right on cue, within 72 hours of the headlines going out, Pfizer announced a Lyme disease vaccine candidate that “demonstrates strong efficacy.”

Isn’t that something.

I know what you’re thinking. You’re thinking I’m supposed to move on. Accept the timing as coincidence. Stop connecting dots. But here’s the thing: the dots aren’t mine to connect. They’re in the documents. Declassified. Public record. And what they show should make your blood run cold.

So bear with me, because I want to walk you through something that most people have never been told. Not because the information is hidden in some dark corner of the internet, but because the people who would normally tell you about it have every reason not to.

The Origin Story They Never Told You

In 1975, a cluster of children in Old Lyme, Connecticut were diagnosed with a mysterious arthritis condition nobody had ever seen before. Within years it spread across the Northeast. Today it’s the most common vector-borne illness in the country, roughly half a million new cases every year.

The official explanation? A naturally occurring tick-borne bacteria that humans simply hadn’t encountered before.

But the geography is strange. The timing is strange. And the town where this disease first appeared sits exactly 13 miles across the Long Island Sound from a secret U.S. government research island called Plum Island.

That’s not where the strangeness ends.

In 1968, seven years before the official “discovery” of Lyme disease, three separate tick-borne diseases emerged simultaneously in that same small region. Not one. Three. Babesiosis, Rocky Mountain spotted fever, and early Lyme arthritis. Three distinct pathogens, same geography, same narrow window of time.

That’s not a coincidence. That’s a statistical impossibility.

By the 1990s, the eastern end of Long Island had the highest concentration of Lyme disease anywhere in the world.  (See link for article)

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**Comment**

I’ve been harping the same exact things for decades.  Glad to be joined by more voices.

The author of the above article has personally seen with his own eyes the prevalence of this horror on steroids.  He dives into the biological weapons program including Project 112, involving every branch of the military and every intelligence agency, Operation Big Itch, Operation Big Buzz, as well as the fact the CIA was dropping infected ticks from airplanes and that 32 operational tasks are confirmed in declassified documents where the methodology sections remain heavily redacted. 

What I appreciate about the article is the fact he states, “It’s almost like they wanted these things to spread,” as well as the fact he doesn’t mince words by stating that the man who built the weapon got credit for discovering the disease.  That would be none other than Willy Burgdorfer – the man known for experimenting with ways to infect ticks with more than one pathogen simultaneously.

To this day, mainstream medicine ignores this very salient fact: Lyme rarely comes alone, significantly complicating cases.  Lyme/MSIDS remains in no-man’s land.

“The story doesn’t fit anything I trained for in my infectious disease fellowship. Even today, I’d posit that PTLD is like an island — it’s still not connected to a lot of the mainstream of medicine.” ~ Dr. John Aucott

There haven’t been any NIH funded RCTs for Lyme disease in the past 20 years and remains void of FDA-approved therapies, void of any consensus on the off-label use of medications, and without any current standard of care or proven mechanisms and pathophysiology, which in my opinion are all good things!  The reason for this is due to the fact the entire debacle needs a major do-over from the get-go. Pleomorphism and polymicrobialism must be taken into account.

Nobody has a clue how being infected with multiple things affects testing which everyone knows is abysmal and misses most cases.

I also appreciate the fact he shows that the institutional response to all inquiries into bioweaponization follows the same sequence every time:

Cooperation collapses into obstruction. Records get restricted or destroyed. A natural origin story gets promoted, a bat market, a warm winter, climate change. Investigators get their credibility attacked instead of their evidence engaged. The institution investigates itself. And then it clears itself.

Bingo.
And now, right on cue, Pfizer has a vaccine. Safe and effective. Say it with me.

For more:

Category:

Activism, Lyme, research, vaccines

Pendulum Ramming Back Against Those Who Stigmatize the Unvaccinated

**UPDATE**

A German court has ordered BioNTech to hand over 32 internal safety, toxicity, and manufacturing records on ‘Comirnaty’ COVID injection affirming injured patients’ right to access data, forcing disclosure. While this is not a final liability ruling, the decision affirms that individuals claiming harm are entitled to access manufacturer’s data.

Pfizer’s former chief toxicologist admits at the German COVID inquiry that the shots ‘should never have been approved.’

According to author and sociology professor Evelyn L. Bush, Ph.D.,  governments and media created a new pariah class: the unvaccinated.  Dr. Bush shows in her new downloadable book that detrimental, fear-driven policies divided families, workplaces, and communities during the COVID era.

Purposefully weaponized stigmatism was used to engineer the population’s participation in an ongoing colossal clinical trial using a completely new mRNA-based ‘vaccine‘ technology that continues to be proven to be dangerous and deadly and cancer causing.

The FREE book reveals the deep human cost of institutional power and gives valuable insights into the mechanics of social control, censorship, and scapegoating so by understanding the patterns, we can resist them better in the future and protect human dignity.

History shows that stigma is rarely accidental — and its consequences are far-reaching and are never temporary.

Pushing back against the tyranny, a Minnesota bill moves to ban medical discrimination by employers, hospitals, governments, and businesses against people for refusing vaccines, RNA, and gene-based products.  The bill shifts legal power away from institutions and back to individuals through enforceable protections and financial liability for violations.

The legislation includes a supremacy clause stating:

“the provisions of this section prevail over any conflicting provisions in general law”

Which means the protections would take precedence over existing laws that conflict with its provisions, unless explicitly exempted.

The bill also includes not only religious exemptions but personal, ethical, or philosophical objections.

What the bill lacks; however, is prohibiting institutions from requiring medical interventions in the first place and it only includes those 18 years of age or older – leaving school, daycare, and pediatric intervention policies outside the bill’s scope. The bill also does not explicitly address whether its protections apply during a public health emergency or executive health orders.

Tennessee lawmakers have also moved to ban forced vaccination and other medical treatments.  They, however, have made it clear with the Constitutional amendment that this holds true even during emergencies.

Former Cleveland Clinic Medical Director Dr. Daniel Neides fights back tears, apologizing to all his ‘vaccinated’ patients because he didn’t provide informed consent. He shares that the only thing doctors are taught about vaccines is to memorize the vaccine schedule in order to pass the medical exam.

Dr. Kelly Victory stated the entire COVID debacle could not have occurred…

“If all physicians had stood shoulder to shoulder with me when I was… suffering the slings and arrows very early on and spoken the truth, this would not have happened. It was precisely because they got physicians on board and willing to continue this that it happened.”

He’s not alone.  Go here to watch a video showing doctor after doctor expressing the limited training they receive about ‘vaccines,’ yet despite appropriate training and information on potential side-effects and injury, doctors often use wellness visits to coerce vaccination.

Doctors never hear:

Federally funded insurance companies are still giving doctors kickbacks for vaccinating patients.

Dr. Joseph Varon also recently wrote a paper titled: When War Teaches Medicine, demonstrating that while good innovations are sometimes forged in crisis, history is replete with examples that innovation can also occur under evil conditions where inhuman treatments and experimentation are state sanctioned, systematic, and organized.  This was experienced during the COVID era and many paid the ultimate price. The deadly hospital protocols alone caused nearly half a million excess deaths in 2020.  Nurses have formed their own network due to the brutally inhumane hospital protocols.

History records medical atrocities such as experiments on prisoners, often without anesthesia, consent or even scientific justification, committed during WWII under the Nazi regime.  In the U.S., the Tuskegee Syphilis study that spanned 4 decades deliberately left African-American men with syphilis untreated even when effective therapy became available.  Then, there’s the recently declassified documents linking Lyme disease to a bioweaponization program where ticks were stuffed with different pathogens and then purposely distributed via airplane.

The recent COVID era allowed ALL to experience this type of institutionalized evil.  Certain individuals were told they were ‘essential,’ and allowed to function, work, get a paycheck, and experience privileges that the ‘non-essential’ people were not. The unvaccinated were blamed for a ‘pandemic’ that wasn’t any worse than a normal flu season. Even German media admits the unvaxxed are ‘winners’ and has demanded the government to apologize for its false claims.

It was amazing to see so many people accept fear-based propaganda without a shred of scientific logic and without pause, despite all the years of being bombarded with education and talk of racism, sexism, and other isms.  Somehow, it became acceptable to mistreat those who questioned the tyranny and/or didn’t swallow the propaganda.

The good news: ‘vaccine’ skepticism in the U.S. is now widespread according to a Politico Poll.

Also, many researchers are taking it upon themselves to comb through studies to point out the many flaws used to take away our freedoms and to push a narrative. The word is out: public health, research and scientific journals are bought out and not to be trusted at face value. Researchers are also following the money and showing the web of deceit behind the curtain that’s being used to control the public.

For those paying attention, the results are in: masks never worked, social distancing was a farce, public figures took to bribing folks with french fries and burgers to get an experimental gene therapy never before used in humans, while there were effective, safe, cheap treatments for COVID that were maligned and even banned by our public health ‘authorities’ and professional medical groups.

Meanwhile, the experimental shots have caused more damage than any other vaccine in the history of VAERS yet are still on the market!

They said THALIDOMIDE was safe

They said CIGARETTES were safe

They said ASBESTOS was safe

They said MERCURY was safe

They said DDT was safe

They said GLYPHOSATE was safe

They said the COVID shot was safe

NOW THEY SAY 5G IS SAFE…..

But, the pendulum is beginning to swing.

Category:

Activism, research, Treatment, vaccines, Viruses

Twenty-Three Years of Unnecessary Suffering: How the Medical Establishment Got Away With Maligning Hormones

https://popularrationalism.substack.com/p/twenty-three-years-of-unnecessary?

Twenty-Three Years of Unnecessary Suffering: What the Women’s Health Initiative Actually Showed — and What the Medical Establishment Did With It

If you are a woman 40 to 50, your choice to pay attention to or ignore this information will – not may, WILL dramatically impact your quality of life.
James Lyons-Weiler, PhD
Apr 12, 2026

On November 10, 2025, the United States Food and Drug Administration quietly did something it almost never does: it reversed itself.

The FDA announced the removal of what it described as “misleading warnings” on hormone replacement therapy, stating in language that should be read carefully by every woman over forty in this country that “estrogen is a key hormone for women’s health where every single part of a woman’s body depends on estrogen to operate at its best — including the brain, bones, heart, and muscles.”

That sentence took twenty-three years to come out of a federal regulatory agency. Those twenty-three years have a body count — not of deaths from hormone therapy, but of preventable fractures, preventable cardiovascular events, preventable cognitive decline, and an incalculable accumulation of unnecessary suffering by women who were told, on the authority of science, to stop their treatment. Or to never start it.

The story of how this happened is the kind of story this publication exists to tell. It involves a landmark study whose design was unsuited to the question it was used to answer, relative risk inflation dressed up as settled science, a medical establishment that moved faster to alarm than to correct, and a generation of women who paid the cost.  (See link for article)

____________

**Comment**

Hormones are huge.  Huge.

Besides helping virtually everything physiologically, they are also drivers of behavior (or lack thereof). However, due to all the xenoestrogens in plastics, pesticides, and personal care products, our society is typically estrogen high – and the wrong, synthetic form at that, disrupting hormonal balance and affecting health negatively.  Just watch a film made in the 70’s or 80’s and then compare the bodies in it to the average population now.

BTW: I’m not a fan at all of equine estrogen due to the horrible way it is made, and I’m not a big fan of synthetic hormones created in a lab often from animal sources (unless for rare special circumstances).  In my opinion, bioidentical hormones that are chemically identical to the hormones naturally produced in the human body are more bioavailable as well as safer.

The sad truth is that the Women’s Health Initiative (WHI) was stopped early due to a small but statistically significant increase in breast cancer, cardiovascular events, and stroke in the hormone group compared to the placebo group.  From that point on, hormones were branded as killers and avoided like the plague by mainstream doctors.

Weiler points out the following problems with the study:

  • the average age of participants in the trial was 63
  • many had pre-existing cardiovascular risk
  • many were put on hormone therapy for the first time years AFTER their estrogen collapsed

Further, there’s the sticky problem of absolute risk – a problem  discussed regarding the COVID jabs as well, and a widely used technique to get a study to say what you want it to say.

The absolute risk increase for breast cancer in the combined hormone group — the number that actually describes what happened to real women in real terms — was approximately eight additional cases per ten thousand women per year, compared to placebo. That is a relative risk increase that translates, in absolute terms, to a risk that is smaller than the baseline absolute risk increase associated with drinking one alcoholic beverage per day, or with being sedentary, or with being obese.

Weiler further adds that while breast cancer is devastating and must be included in the conversation:

relative risk, stripped of its denominator, is a rhetorical instrument. When the baseline rate is small, a relative risk of 1.26 can be presented as a twenty-six percent increase in breast cancer — which is how it was widely framed — or as eight additional cases per ten thousand women per year in a specific, older population — which is what it actually meant. These are not equivalent framings. The first drives panic. The second permits informed decision-making.

The risks became headlines but the significant benefits in reduced hip fractures, colorectal cancer, and relief from vasomotor symptoms became the footnote.  This is how you rig a study.

Researchers now understand that  there is a critical window regarding HRT and the benefit-risk profile is different depending on when it is initiated.

I short, women who begin HRT within a ten year window of the onset of menopause (or before age 60) have cardiovascular outcomes that are neutral to favorable.  Women who start HRT a decade or more after menopause show a less favorable profile because the vascular and neural adaptation to estrogen withdrawal have already occurred.

Who benefits from this travesty?
Big Pharma of course

Women who stopped taking HRT switched over to individual pharmacological agents targeting individual symptoms – and there’s a bevy of them!  Since the systemic solution of hormone therapy that would have solved all the symptoms was maligned, Big Pharma now had a collection of targeted interventions bringing in separate revenue streams!

Weiler then drives the message home by showing the HRT saga is not an isolated event but a documented pattern of what happens when:

a large, expensive, federally funded study  conducted on a population that does not match the clinical target using a formulation or intervention that does not match the clinical practice being evaluated, producing findings that are communicated in relative rather than absolute terms, and whose findings are translated into guidelines and clinical practice with a speed and thoroughness that is never matched by the subsequent corrections.

And this, right here, is why I’m against ANY large, expensive, federally funded study for Lyme disease – and for the same reasons.

The WHI results changed clinical practice within months but took a decade and a half to change – yet, are still not uniformly reflected in practice.  

For more:

Category:

Activism, Hormones, research, Treatment

1 in 3 Cancer-Free: Ivermectin Trial Stuns, but RESET-5 Aims Even Higher

https://zenodo.org/records/19455636

Real-World Clinical Outcomes of Ivermectin and Mebendazole in Cancer Patients: Results from a Prospective Observational Cohort

Authors/Creators

Nicolas Hulscher, MPH1, 2, Kelly Victory, MD2, James A. Thorp, MD2, Drew Pinsky, MD2, Alejandro Diaz-Villalobos, MD2, Peter Gillooly, MSc2, Foster Coulson2, Melissa Annazone2, Chloe Radesi2, Jessica Brooks2, Peter A. McCullough, MD, MPH1, 2, Harvey Risch, MD, PhD3, 2

April 7, 2026

Description

Abstract

Background: Drug repurposing offers a pathway to identify accessible, low-toxicity cancer therapies. Ivermectin and mebendazole have demonstrated multi-target anti-cancer activity in preclinical models, including the inhibition of cancer cell proliferation and the targeting of cancer stem cells. This paper evaluates real-world patient-reported outcomes, safety, and adherence in a cohort of cancer patients utilizing this combination protocol.

Methods: We analyzed a prospective observational cohort of 197 cancer patients who were prescribed ivermectin and mebendazole off-label through a telemedicine platform by licensed U.S. healthcare providers. Participants received compounded oral capsules containing 25 mg ivermectin and 250 mg mebendazole. As part of a clinical program evaluation, data were collected via voluntary, standardized digital surveys at baseline and at approximately 6-month follow-up. Of the initial cohort (N = 197), baseline characteristics, including cancer type and disease status, were assessed. A total of 122 participants completed the follow-up survey (61.9% response rate) to evaluate self-reported cancer outcomes, medication adherence, and adverse events. 95% confidence intervals (CI) were calculated for primary outcome measures using the Wilson score method. Dose-stratified analyses for outcomes and safety were conducted using Chi-square statistics.

Results: The cohort represented a diverse clinical profile of cancer patients, with mean age of 67 years and nearly balanced sex distribution (52.3% male, 47.7% female). Cancer types included prostate (27.9%), breast (18.3%), lung (8.6%), colon (5.1%), urologic (4.6%), pancreatic (3.0%), liver (2.5%), gynecologic (2.5%), and hematologic (2.5%) malignancies. At enrollment, participants had a median duration since initial diagnosis of 1.2 years, with 37.1% experiencing active disease progression. At 6-month follow-up, medication adherence was high with 86.9% of participants completing the full initial 90-capsule ivermectin-mebendazole prescription and 66.4% remaining on the protocol at 6 months. The Clinical Benefit Ratio (CBR) was 84.4% (95% CI: 77.0–89.8%). Notably, 48.4% (95% CI: 39.7–57.1%) of the cohort reported the strongest positive outcomes, consisting of regression (15.6%; 95% CI: 10.2–23.0%) or no current evidence of disease (NED, 32.8%; 95% CI: 25.1–41.5%). Disease stability was reported to be maintained in 36.1% (95% CI: 28.1–44.9%) of participants, while 15.6% (95% CI: 10.2–23.0%) reported disease progression. While 25.4% reported mild side effects (primarily gastrointestinal), 93.6% of those affected continued treatment through minor dose adjustments. Some participants reported concurrent conventional therapies, including chemotherapy (27.9%), radiation therapy (21.3%), and surgery (19.7%), as well as adjunctive interventions such as supplement use (49.2%), dietary modification (37.7%), and other integrative approaches.

Conclusions: In this prospective real-world cohort, the combination of ivermectin and mebendazole was associated with high rates of self-reported clinical benefit, with nearly half of participants reporting tumor regression or no current evidence of disease across a heterogeneous population of cancer patients. These findings provide a compelling clinical signal that these well-tolerated, repurposed agents may offer therapeutic benefit. However, given the observational design, reliance on self-reported outcomes, and potential for selection bias and uncontrolled confounding, these findings should be interpreted as hypothesis-generating. Urgent prospective, randomized, placebo-controlled clinical trials are warranted to validate these observations and further define optimal dosing strategies. (Go to link for full-length study)

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**Comment**

http://

Could These Overlooked Drugs Be a Cancer Game-Changer?

Dr. Ken Stoller, April 12, 2026

For a wonderful breakdown of the study:  https://justusrhope.substack.com/p/1-in-3-cancer-free-ivermectin-trial?  Excerpt:

Dosages and Concurrent Therapies

Patients were prescribed the medications off-label through a telemedicine platform. They received compounded oral capsules containing:

  • 25 mg of Ivermectin
  • 250 mg of Mebendazole

The study noted that these were not strictly monotherapies. Many patients were undergoing concurrent conventional treatments, including chemotherapy (27.9%), radiation therapy (21.3%), and surgery (19.7%). Additionally, many used adjunctive interventions such as supplements (49.2%) and dietary modifications (37.7%).

Study Completion and Attrition

Of the initial 197 patients, 75 patients failed to complete the study (meaning they did not complete the 6-month follow-up survey).

  • A total of 122 participants completed the 6-month follow-up survey, resulting in a 61.9% response rate.
  • Among the 122 who responded, adherence was high: 86.9% completed the full initial 90-capsule prescription, and 66.4% chose to remain on the protocol at the 6-month mark.

Clinical Outcomes and Tolerability

The authors reported an overall Clinical Benefit Ratio (CBR) of 84.4% among the 122 patients who completed the survey. The self-reported outcomes broke down as follows:

  • No Evidence of Disease (NED): 32.8%
  • Disease Stabilization: 36.1%
  • Tumor Regression: 15.6%
  • Disease Progression: 15.6%

Within the article, Justuserhope asked AI to evaluate the benefit of adding one agent at a time from the RESET-5 Protocol (Mebendazole, ivermectin, sulforaphane, metformin, and aged garlic extract) to the Hulscher et. al study.  The full RESET-5 reduces the likelihood of resistance development, enhances immune function, and depletes tumors of a critical survival tool – compensatory glutathione production.

The full RESET-5 Protocol boosts improvement even further by 30-40%.

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**Comment**

For those of you studying this, 25 mg of ivermectin and 250mg of Mebendazole are considered pretty low dosages.  Many patients are taking much more than that, so the fact they are getting such great improvement with such low dosages is fairly amazing.  Lower dosages typically mean lower side-effects so this should be safe for nearly all to take.  Share with your doctor and work together to get the best fit.

For more:

Category:

Cancer, research, Treatment